| Figure 8. The M/G1 clusters. Three clusters of M/G1 genes from Figure 3B are shown in more detail. Each contains genes involved in cell adhesion, chromosome metabolism and RAS signal transduction and is annotated as described in Figure 6. Cluster A, (NODE568X) contains 104 clones (33 ESTs and hypothetical proteins); 37% show peak expression in G2/M and 63% show peak expression in M/G1. Cluster B, (NODE688X) is comprised of 12 clones (3 ESTs), including CDK7, the cyclin dependent kinase (cdk) of the cdk-activating complex (CAK); 92% show peak expression in M/G1. Cluster C, (NODE988X) which peaks in late M/G1, contains 25 clones (8 ESTs and hypothetical proteins); 96% peak in M/G1. The full clusters with all gene names, phase assignments and annotations can be viewed in Supplementary Figure 14. |
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