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Figure 8. Genes repressed specifically by MMS treatment. The expression of genes repressed by MMS treatment are shown following MMS exposure and ionizing radiation (IR). The genes are organized as seen in the hierarchical cluster of the entire DNA damage dataset. The response of these genes to ROX1 overexpression is also shown. Timepoints are the same as described in Figure 1, and the color scale key indicating the changes in transcript levels is shown at the bottom of the figure. Adjacent genes on this display that share high sequence similarity and may therefore be subject cross-hybridization in the microarray analysis are indicated by an asterisk. View the MEME (Bailey and Elkan, 1994) output of the putative Hap1p binding site. |