Here are a few web links that may be useful for
the tissue microarray community.
If you feel that there are other useful links to add to this list,
please email me and I will
add the link to this list. Also, please notify me if any links are broken.
Equipment and Software
Laboratories - makers of the BLISS microscope system designed
for tissue microarray image acquisition. (added 4-12-03)
Eisen Lab -
The laboratory of Dr. Mike Eisen, author of the Cluster and TreeView
software. Note: as of 4-12-03, the most recent of Cluster (2.2) has
some significant bugs; try to use Version 2.11 if available. (added
TMA Foresight (Premier Biosoft): a tissue microarray data analysis tool designed to
explore the relatedness of prognostic marker expression and clinico-pathological
variates with the outcome. It identifies important prognostic marker(s) that
influence the outcome and identifies
prognostically significant clusters of
patients. Based on the data provided it helps decide the risk group of a cohort.
TMA Foresight uses statistical techniques
such as Cox regression, Hierarchical Clustering and Kaplan-Meier plots to interpret
the results of a TMA experiment. (added 1-17-07)
Alternative TMA Data Acquisition/Processing Strategies
- a set of TMA tools, done in Microsoft Excel, is described by a group
headed by Dr. Giorgio Cattoretti.
These tools (which don't involve macros) may be helpful towards the
organization of the initial data acquisition and scoring of TMA images
and data, and is most suitable for those who work on a smaller scale
(e.g. single or a few arrays; array size of ~50-300 spots). Here's a link
to the lab website, which contains many other protocols related to
TMAs and in other areas. (added 4-12-03)
Message from Dr. George
McNamara, Image Core Facility at the Children's Hospital at Los
Angeles (associated with USC), suggesting a more inexpensive solution
to TMA image acquisition. He references this paper here: Pubmed;
Histochemistry and Cytochemistry (requires an online
subscription) (added 4-12-03).
Disclaimer: links provided here are for the benefit of the TMA
community. Their presence on this page does not constitute an
endorsement, nor lack thereof, of the indicated information by the
authors of the Stanford TMA system.