Yeast Evolution Experiment Home

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  • How do I interpret the red and green images?
    The data for one gene corresponds to one row, and data points for each experiment are the columns. The ratio of induction/repression is such that the magnitude is indicated by the intensity of the colors displayed. If the color is black then the ratio of control to experimental cDNA is equal to 1, while the brightest colors (red and green) represent a ratio of 8 to 1. Ratios greater than 8 are displayed as the brightest color. In all cases red indicates an increase in mRNA abundance while green indicates a decrease in abundance in the experimental sample with respect to the control. Gray areas (when visible) indicate absent data, or data of low quality.
  • Why do some genes return more 'similar genes' than others?
    We calculated similarity scores using a correlation algorithm, and only consider as significant those correlation scores above 0.5, where two genes had data for all four experiments. One gene therefore may have many more significantly similar genes than another.
  • Problems viewing images
    We recomend that you upgrade to the latest browser versions. For Netscape this is version 4.6 for PowerPC Macintoshes, and Windoze 95/98/NT PCs. For 68K Macintoshes, and Windoze 3.1 PCs you should get Netscape version 4.08. If you use Internet Explorer you should use version 4.5 on a Mac, and version 5.0 on a PC. If you still have problems then it may be that your computer doesn't have enough memory, or a fast enough processor - buy a new G3.
  • Where can I find descriptions of the experiments?
    Full descriptions of all materials and methods are published in the paper.
  • If you still have a question that is not answerered here please email Tracy Ferea .