URL: http://genome-www.stanford.edu/mammal/#orfs
DATA: p_150.dat
REFERENCE:
Botstein, D., Chervitz, S.A., and Cherry, J.M., (1997), "Yeast as a Model Organism", Science 277: 1259.
CONTACT: sac@genome.stanford.edu GENBANK UPDATE: 22 July 1997 236 unique yeast ORFs ORF NAME LOCUS PRODUCT/DESCRIPTION -------- ----- ---------------------------------------- YNR016C ACC1 acetyl-CoA carboxylase YLR304C ACO1 Aconitase, mitochondrial YFL039C ACT1 Actin YNL220W ADE12 adenylosuccinate synthetase YLR359W ADE13 Adenylosuccinate Lyase YLR028C ADE16 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR) transformylase/IMP cyclohydrolase YMR120C ADE17 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR) transformylase/IMP cyclohydrolase YGR204W ADE3 C1-5,6,7,8-tetrahydrofolate synthase YGL234W ADE5,7 glycinamide ribotide synthetase and aminoimidazole ribotide synthetase YOR335C ALA1 Cytoplasmic alanyl-tRNA synthetase gene YML035C AMD1 putative alpha-mannosidase YGL156W AMS1 vacuolar alpha mannosidase YHR018C ARG4 argininosuccinate lyase YJR065C ARP3 actin-relatedgene YMR301C ATM1 mitochondrial ABC transporter protein YBL099W ATP1 mitochondrial F1F0-ATPase alpha subunit YJR121W ATP2 F(1)F(0)-ATPase complex beta subunit, mitochondrial YLR175W CBF5 major low affinity 55 kDa Centromere/microtubule binding protein YIL142W CCT2 Cytoplasmicchaperonin of the Cct ring complex related to Tcp1p; subunit beta YJL014W CCT3 Cytoplasmic chaperonin subunit gamma YDL143W CCT4 mitochondrial adenine nucleotide carrier isoform, subunit delta YJR064W CCT5 subunit of chaperonin subunit epsilon YDR188W CCT6 Cytoplasmicchaperonin of the Cct ring complex (previously called TCP1 or TRiC), distantly related to Tcp1p and to Hsp60 YJL111W CCT7 Componentof Chaperonin Containing T-complex subunit seven YAL038W CDC19 Pyruvate kinase YDL102W CDC2 large subunit of DNA polymerase III YLR274W CDC46 Memberof complex that acts at ARS's to initiate replication YBR202W CDC47 Essentialfor initiation of DNA replication YDL126C CDC48 Microsomalprotein of CDC48/PAS1/SEC18 family of ATPases; full length homology to mammalian protein VCP; involved in secretion, peroxisome formation and gene expression YPR019W CDC54 essentialfor initiation of DNA replication; homolog of S. pombe CDC21 YGL190C CDC55 Protein phosphatase 2A regulatory subunit B YDL164C CDC9 DNA ligase YGL206C CHC1 clathrin heavy chain YER164W CHD1 transcriptional regulator YML057W CMP2 catalytic A subunit of calcineurin YLR433C CNA1 Calcineurin subunit A; Protein phosphatase 2B catalytic subunit A1 YJR109C CPA2 carbamyl phosphate synthetase YOR259C CRL13 ATPase; component of the 26S proteasome cap subunit YGR218W CRM1 Chromosome region maintenance protein YGL238W CSE1 Proteinrequired for accurate mitotic chromosome segregation YDR256C CTA1 catalase A YPL119C DBP1 putative ATP-dependent RNA helicase; Dead box protein YNL112W DBP2 ATP-dependent RNA helicase of DEAD box family YOR204W DED1 ATP-dependentRNA helicase of DEAD box family; suppressor of a pre-mRNA splicing mutation, prp8-1 YDL160C DHH1 PutativeRNA helicase of DEAD box family, required for Rap1p localization to telomeres YLL001W DNM1 Dynamin-related protein YLL018C DPS1 Aspartyl-tRNA synthetase, cytosolic YAL026C DRS2 Membrane-spanning Ca-ATPase (P-type),member of the cation transport (E1-E2) ATPases YKR054C DYN1 heavy chain of cytoplasmic dynein YEL030W ECM10 ExtraCellularMutant YOR133W EFT1 translation elongation factor 2 (EF-2) YDR385W EFT2 translation elongation factor 2 (EF-2) YGR254W ENO1 enolase I YHR174W ENO2 enolase YOR393W ERR1 enolase homolog YFL022C FRS2 Phenylalanyl-tRNA synthetase, beta subunit, cytoplasmic YPL262W FUM1 mitochondrial and cytoplasmic fumarase (fumarate hydralase) YER025W GCD11 gamma subunit of translational initiation factor eIF-2 YGL195W GCN1 translational activator of GCN4 through activation of GCN2 in response to starvation YER136W GDI1 GDP dissociation inhibitor YKL104C GFA1 Glutamine_fructose-6-phosphate amidotransferase (glucoseamine-6-phosphate synthase) YEL011W GLC3 1,4-glucan-6-(1,4-glucano)-transferase YER133W GLC7 protein phosphatase type I YHR183W GND1 6-phosphogluconatedehydrogenase, decarboxylating; converts 6-phosphogluconate + NADP to ribulose-5-phosphate + NADPH + CO2 YGR256W GND2 6-phosphogluconate dehydrogenase YPR160W GPH1 Glycogen phosphorylase YBR121C GRS1 Glycyl-tRNA synthase YFR015C GSY1 Glycogen synthase (UDP-gluocse--starch glucosyltransferase) YLR258W GSY2 Glycogen synthase (UDP-gluocse--starch glucosyltransferase) YJL033W HCA4 putative RNA helicase YMR207C HFA1 UNKNOWN YML075C HMG1 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase isozyme YPL204W HRR25 casein kinase I isoform YMR186W HSC82 constitutively expressed heat shock protein YLR259C HSP60 heat shock protein 60; chaperonin protein YPL240C HSP82 heat shock protein YPR033C HTS1 cytoplasmic and mitochondrial histidine tRNA synthetases YDL066W IDP1 Mitochondrial form of NADP-specific isocitrate dehydrogenase YLR174W IDP2 Cytosolic form of NADP-dependent isocitrate dehydrogenase YNL009W IDP3 peroxisomal NADP-dependent isocitrate dehydrogenase YBL076C ILS1 cytoplasmic isoleucyl-tRNA synthetase YJL034W KAR2 Homologue of mammalian BiP (GPR78) protein; member of the HSP70 gene family YGL173C KEM1 strand exchange protein 1, 5'->3' exoribonuclease YIL125W KGD1 alpha-ketoglutarate dehydrogenase YDR037W KRS1 lysyl-tRNA synthetase YFL018C LPD1 dihydrolipoamide dehydrogenase precursor (mature protein is the E3 component of alpha-ketoacid dehydrogenase complexes) YBL023C MCM2 Memberof complex that acts at ARS's to initiate replication YEL032W MCM3 Memberof complex that acts at ARS's to initiate replication YLR069C MEF1 mitochondrial elongation factor G-like protein YGR264C MES1 methionyl tRNA synthetase YOR330C MIP1 catalytic subunit of mitochondrial DNA polymerase YBR084W MIS1 mitochondrial C1-tetrahydroflate synthase YOL090W MSH2 mutS homolog involved in nuclear DNA repair YHR023W MYO1 myosin class V, alpha-helical middle YOR326W MYO2 myosin-1 YKL129C MYO3 myosin I YAL029C MYO4 myosin YLR382C NAM2 mitochondrial leucyl tRNA synthetase YMR080C NAM7 putative helicase YNL061W NOP2 90-kDa protein, located in nucleolus, that is homologous to a human proliferation-associated nucleolar protein, p120 YKL068W NUP100 Nuclear pore complex protein homologous to Nup116p YER165W PAB1 Poly(A) binding protein, cytoplasmic and nuclear YGR240C PFK1 phosphofructokinase alpha subunit YMR205C PFK2 phosphofructokinase beta subunit YBR196C PGI1 phoshoglucoisomerase YCR012W PGK1 3-phosphoglycerate kinase YBL022C PIM1 mitochondrial ATP-dependent protease YGL167C PMR1 Ca++-Pump, ATPase YNL102W POL1 DNA polymerase I YNL262W POL2 DNA polymerase II YDL134C PPH21 serine-threonine protein phosphatase 2A YDL188C PPH22 serine-threonine protein phosphatase 2A YKR086W PRP16 putative ATP-binding protein YER013W PRP22 helicase-like protein YHR216W PUR5 UNKNOWN YGL062W PYC1 pyruvate carboxylase YBR218C PYC2 pyruvate carboxylase YJR035W RAD26 Proteinhomologous to Cockayne syndrome B gene ERCC6 YER171W RAD3 DNAhelicase component of transcription factor b (yeast homolog of human TFIIH) YGL163C RAD54 Proteinrequired for recombination and repair of X-ray damage YOR207C RET1 second-largest subunit of RNA polymerase III YER070W RNR1 ribonucleotide reductase YJL026W RNR2 small subunit of ribonucleotide reductase YIL066C RNR3 Ribonucleotide reductase (ribonucleoside-diphosphate reductase) large subunit YOR151C RPB2 RNA polymerase II subunit YNL330C RPD3 Transcriptionmodifier YDL140C RPO21 RNA polymerase II large subunit YOR116C RPO31 RNA polymerase III large subunit YER125W RSP5 Suppressorof mutations in SPT3 YOR014W RTS1 highcopy suppressor of rox3 and a multicopy suppressor of hsp60-ts alleles YER043C SAH1 putative S-adenosyl-L-homocysteine hydrolase YLR180W SAM1 S-adenosylmethionine synthetase YDR502C SAM2 S-adenosylmethionine synthetase YKL148C SDH1 flavoprotein subunit of succinate dehydrogenase YBR080C SEC18 cytoplasmic protein involved in protein transport between ER and Golgi YPR181C SEC23 cytoplasmic GTPase-activating protein YDR238C SEC26 UNKNOWN YGL137W SEC27 UNKNOWN YIL075C SEN3 involvedin tRNA processing YDL168W SFA1 Long-chain alcohol dehydrogenase (glytathione-dependent formaldehyde dehydrogenase) YLR058C SHM2 serine hydroxymethyltransferase YLR398C SKI2 antiviral protein, putative helicase YOR290C SNF2 transcriptional regulator YNL189W SRP1 karyopherin alpha homolog of 60 kDa YAL005C SSA1 Heat shock protein of HSP70 family, cytoplasmic YLL024C SSA2 member of 70 kDa heat shock protein family YBL075C SSA3 member of 70 kDa heat shock protein family YER103W SSA4 member of 70 kDa heat shock protein family YDL229W SSB1 Heat shock protein of HSP70 family, cytoplasmic YNL209W SSB2 Heat shock protein of HSP70 family, homolog of SSB1 YJR045C SSC1 Mitochondrial matrix protein involved in protein import; subunit of SceI endonuclease YIL143C SSL2 DNA helicase homolog; homolog of human XPBC YLR389C STE23 UNKNOWN YIL126W STH1 helicase related protein, snf2 homolog YGL022W STT3 UNKNOWN YGL048C SUG1 ATPase YDR172W SUP35 putative translation factor YBR143C SUP45 Recessiveomnipotent suppressor YOR063W TCM1 ribosomal protein L3 YDR212W TCP1 chaperonin subunit alpha YJL052W TDH1 Glyceraldehyde-3-phosphate dehydrogenase 1 YJR009C TDH2 glyceraldehyde 3-phosphate dehydrogenase YGR192C TDH3 Glyceraldehyde-3-phosphate dehydrogenase 3 YPR080W TEF1 translational elongation factor EF-1 alpha YBR118W TEF2 translational elongation factor EF-1 alpha YDL185W TFP1 catalytic subunit of the vacuolar H(+)ATPase YIL078W THS1 Threonyl-tRNA synthetase, cytoplasmic YKR059W TIF1 translation initiation factor YJL138C TIF2 translation initiation factor YOL006C TOP1 topoisomerase I YNL088W TOP2 topoisomerase II YJR066W TOR1 phosphatidylinositol kinase homolog YKL203C TOR2 phosphatidylinositol kinase homolg YML085C TUB1 alpha-tubulin YFL037W TUB2 beta-tubulin YML124C TUB3 alpha-tubulin YKL210W UBA1 ubiquitin activating enzyme YLL039C UBI4 ubiquitin YJL130C URA2 carbamoyl-phophate synthetase, aspartate transcarbamylase, and glutamine amidotransferase YBL039C URA7 CTP synthase YJR103W URA8 CTP synthase YGR094W VAS1 mitochondrial and cytoplasmic valyl-tRNA synthetase YBR127C VMA2 VacuolarH-ATPase regulatory subunit (subunit b), 60 kDa subunit of V1 sector YOR270C VPH1 95 kDa protein required for assembly and activity of vacuolar H(+) ATPase YPR173C VPS4 defectivein vacuolar protein sorting YBR245C YBR245C UNKNOWN YDR135C YCF1 Metalresistance protein with similarity to human cystic fibrosis protein CFTR and multidrug resistance proteins YDL084W YDL084W UNKNOWN YDL145C YDL145C UNKNOWN YDR021W YDR021W UNKNOWN YDR091C YDR091C UNKNOWN YDR093W YDR093W UNKNOWN YDR190C YDR190C UNKNOWN YER073W YER073W UNKNOWN YER166W YER166W UNKNOWN YGL120C YGL120C UNKNOWN YGL201C YGL201C UNKNOWN YGL245W YGL245W UNKNOWN YHL035C YHL035C UNKNOWN YHR020W YHR020W UNKNOWN YHR027C YHR027C UNKNOWN YJL045W YJL045W UNKNOWN YJL050W YJL050W UNKNOWN YJL200C YJL200C UNKNOWN YKL035W YKL035W UNKNOWN YKL215C YKL215C UNKNOWN YLL015W YLL015W UNKNOWN YLL048C YLL048C UNKNOWN YLR369W YLR369W UNKNOWN YLR432W YLR432W UNKNOWN YML056C YML056C UNKNOWN YMR049C YMR049C UNKNOWN YMR109W YMR109W UNKNOWN YMR162C YMR162C UNKNOWN YMR189W YMR189W UNKNOWN YMR290C YMR290C UNKNOWN YMR323W YMR323W UNKNOWN YNL161W YNL161W UNKNOWN YNL247W YNL247W UNKNOWN YNR053C YNR053C UNKNOWN YOL097C YOL097C UNKNOWN YGR281W YOR1 ABC transporter YOR304W YOR304W UNKNOWN YOR347C YOR347C UNKNOWN YOR356W YOR356W UNKNOWN YOR374W YOR374W UNKNOWN YPL217C YPL217C UNKNOWN YPL281C YPL281C UNKNOWN YPR010C YPR010C UNKNOWN YPR081C YPR081C UNKNOWN YPR184W YPR184W UNKNOWN YLR277C YSH1 subunit of Polyadenylation factor I (PF I) YOR117W YTA1 Probable26S protease subunit and member of the CDC48/PAS1/SEC18 family of ATPases YDR394W YTA2 UNKNOWN YKL145W YTA3 UNKNOWN YDL007W YTA5 Probable26S protease subunit and member of CDC48/PAS1/SEC18 family of ATPases