URL: http://genome-www.stanford.edu/mammal/#orfs
DATA: p_40.dat
REFERENCE:
Botstein, D., Chervitz, S.A., and Cherry, J.M., (1997), "Yeast as a Model Organism", Science 277: 1259.
CONTACT: sac@genome.stanford.edu GENBANK UPDATE: 22 July 1997 1089 unique yeast ORFs ORF NAME LOCUS PRODUCT/DESCRIPTION -------- ----- ---------------------------------------- YMR056C AAC1 mitochondrial ADP/ATP translocator YBR085W AAC3 mitochondrial ADP/ATP translocator YHR047C AAP1' arginine/alanine aminopeptidase YKL106W AAT1 aspartate aminotransferase, mitochondrial YLR027C AAT2 aspartate aminotransferase, cytosolic YGL119W ABC1 multicopysuppressor of a cytochrome b mRNA translation defect, essential for the electron transfer in the bc1 complex YNR016C ACC1 acetyl-CoA carboxylase YLR304C ACO1 Aconitase, mitochondrial YJR095W ACR1 protein related to mitochondrial carriers YFL039C ACT1 Actin YDR448W ADA2 Transcriptionaladaptor required for function of certain acidic activation domains; forms a complex with GCN5 and ADA3 (NNG1) YNL220W ADE12 adenylosuccinate synthetase YLR359W ADE13 Adenylosuccinate Lyase YLR028C ADE16 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR) transformylase/IMP cyclohydrolase YMR120C ADE17 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR) transformylase/IMP cyclohydrolase YGR204W ADE3 C1-5,6,7,8-tetrahydrofolate synthase YMR300C ADE4 phosphoribosylpyrophosphate amidotransferase YGL234W ADE5,7 glycinamide ribotide synthetase and aminoimidazole ribotide synthetase YGR061C ADE6 5'-phosphoribosylformyl glycinamidine synthetase YDR226W ADK1 cytosolic adenylate kinase YER170W ADK2 Adenylate kinase (mitochondrial GTP:AMP phosphotransferase) YCR011C ADP1 ATP-dependent permease YLR397C AFG2 homology to the CDC48 gene product YER017C AFG3 ATP-dependent metalloprotease YOR335C ALA1 Cytoplasmic alanyl-tRNA synthetase gene YMR170C ALD2 aldehyde dehydrogenase, (NAD(P)+), likely cytosolic YMR169C ALD3 similarityto aldehyde dehydrogenases (NAD(P)+) YPL061W ALD6 cytosolic aldehyde dehydrogenase YBR243C ALG7 UDP-N-acetyl-glucosamine-1-P transferase (GPT) YML035C AMD1 putative alpha-mannosidase YGL156W AMS1 vacuolar alpha mannosidase YJR047C ANB1 anaerobically expressed form of translation initiation factor eIF-5A YKL157W APE2 aminopeptidase yscII YJR005W APL1 beta-adaptin, large subunit of the clathrin-associated protein complex YKL135C APL2 beta-adaptin, large subunit of clathrin associated protein YPL259C APM1 medium subunit of the clathrin-associated protein complex YOL062C APM4 Clathrin associated protein, medium subunit YLR170C APS1 clathrin-associated protein complex, small subunit YJL024C APS3 similar to Aps1p and mammalian small subunit (sigma-2 adaptin) of plasma membrane-associated clathrin assembly complex (AP-2) YHR013C ARD1 subunit of the major N alpha-acetyltransferase YDL192W ARF1 ADP-ribosylation factor YDL137W ARF2 ADP-ribosylation factor 2 YOR094W ARF3 GTP-binding ADP-ribosylation factor YOL058W ARG1 arginosuccinate synthetase YJL088W ARG3 Ornithine carbamoyltransferase YHR018C ARG4 argininosuccinate lyase YDR376W ARH1 adrenodoxin oxidoreductase homolog YBR164C ARL1 ADP-ribosylation factor-like protein 1 YGL202W ARO8 aromatic amino acid aminotransferase YHR129C ARP1 actin-relatedprotein of the dynactin complex YDL029W ARP2 actin-related protein YJR065C ARP3 actin-relatedgene YPR145W ASN1 asparagine synthetase YGR124W ASN2 asparagine synthetase YMR301C ATM1 mitochondrial ABC transporter protein YBL099W ATP1 mitochondrial F1F0-ATPase alpha subunit YJR121W ATP2 F(1)F(0)-ATPase complex beta subunit, mitochondrial YBR039W ATP3 gamma subunit of mitochondrial ATP synthase YPR122W AXL1 putative homolog of human insulin-degrading endoprotease YHR208W BAT1 Branched-Chain Amino Acid Transaminase YJR148W BAT2 Branched-Chain Amino Acid Transaminase YLR399C BDF1 nuclearprotein required for sporulation; possible component of chromatin; bromodomain protein which affects synthesis of snRNA YMR116C BEL1 G-betalike protein YPR176C BET2 Geranylgeranyltransferase Type II beta subunit YER177W BMH1 Homolog of mammalian 14-3-3 proteins YDR099W BMH2 Homolog of mammalian 14-3-3 proteins YCR032W BPH1 BeigeProtein Homologue 1 YGR246C BRF1 RNA polymerase III transcription factor with homology to TFIIB YML102W CAC2 p60 subunit of the yeast Chromatin Assembly Factor-I (CAF-I) YPL048W CAM1 Calciuim and phospholipid binding protein homologous to translation elongation factor-1 gamma (EF-1 gamma) YIL034C CAP2 beta subunit of capping protein YPL111W CAR1 arginase YLR438W CAR2 ornithine aminotransferase YML042W CAT2 Carnitine O-acetyltransferase, peroxisomal and mitochondrial YOR125C CAT5 UNKNOWN YLR175W CBF5 major low affinity 55 kDa Centromere/microtubule binding protein YDR270W CCC2 Copper-transportingP-type ATPase with similarity to human Menkes and Wilsons genes YIL142W CCT2 Cytoplasmicchaperonin of the Cct ring complex related to Tcp1p; subunit beta YJL014W CCT3 Cytoplasmic chaperonin subunit gamma YDL143W CCT4 mitochondrial adenine nucleotide carrier isoform, subunit delta YJR064W CCT5 subunit of chaperonin subunit epsilon YDR188W CCT6 Cytoplasmicchaperonin of the Cct ring complex (previously called TCP1 or TRiC), distantly related to Tcp1p and to Hsp60 YJL111W CCT7 Componentof Chaperonin Containing T-complex subunit seven YJL008C CCT8 Componentof Chaperonin Containing T-complex subunit eight YCR002C CDC10 conserved potential GTP-ginding protein YJR076C CDC11 Component of 10 nm filaments of mother-bud neck YHR107C CDC12 Component of 10 nm filaments of mother-bud neck (septin) YAR019C CDC15 protein kinase domain YKL022C CDC16 potential metal-binding, nucleic acid-binding protein YAL038W CDC19 Pyruvate kinase YDL102W CDC2 large subunit of DNA polymerase III YGL116W CDC20 beta-transducin homolog YOR074C CDC21 Thymidylate synthase YBL084C CDC27 Proteinrequired for cell cycle YBR160W CDC28 protein kinase catalytic subunit YLR314C CDC3 Component of 10 nm filaments of mother-bud neck YOR257W CDC31 Calcium-bindingprotein of spindle pole body YLR229C CDC42 member of the Rho subfamily of Ras-like proteins YLR274W CDC46 Memberof complex that acts at ARS's to initiate replication YBR202W CDC47 Essentialfor initiation of DNA replication YDL126C CDC48 Microsomalprotein of CDC48/PAS1/SEC18 family of ATPases; full length homology to mammalian protein VCP; involved in secretion, peroxisome formation and gene expression YMR001C CDC5 protein kinase which functions at the G(sub)2/M boundary YDL132W CDC53 Celldivision cycle blocked at 36 degree C YPR019W CDC54 essentialfor initiation of DNA replication; homolog of S. pombe CDC21 YGL190C CDC55 Protein phosphatase 2A regulatory subunit B YDL017W CDC7 protein kinase required for initiation of mitotic DNA synthesis YDL164C CDC9 DNA ligase YBR029C CDS1 CDP-diacylglycerol synthase, CTP-phosphatidic acid cytidylyltransferase, CDP-diglyceride synthetase YGL206C CHC1 clathrin heavy chain YER164W CHD1 transcriptional regulator YPL008W CHL1 kinetochore protein in the DEAH box family YEL061C CIN8 Kinesin-relatedprotein involved in establishment and maintenance of mitotic spindle YIL035C CKA1 alpha subunit of casein kinase II YOR061W CKA2 alpha' subunit of casein kinase II YGL019W CKB1 casein kinase II beta chain YOR039W CKB2 Casein kinase II, beta' subunit YNL298W CLA4 protein kinase YGR108W CLB1 G(sub)2-specific B-type cyclin YPR119W CLB2 G(sub)2-specific B-type cyclin YDL155W CLB3 G(sub)2-specific B-type cyclin YLR210W CLB4 G(sub)2-specific B-type cyclin YGR109C CLB6 B-type cyclin YBR109C CMD1 Calmodulin YFR014C CMK1 calmodulin dependent protein kinase YOL016C CMK2 calmodulin dependent protein kinase YML057W CMP2 catalytic A subunit of calcineurin YLR433C CNA1 Calcineurin subunit A; Protein phosphatase 2B catalytic subunit A1 YKL190W CNB1 catalytic B subunit of calcineurin YAL058W CNE1 Calnexin and calreticulin homolog YOR316C COT1 Proteininvolved in cobalt accumulation; dosage dependent suppressor of cobalt toxicity YPL172C COX10 Putative farnesyl transferase required for heme A synthesis YPL132W COX11 Putative heme A biosynthetic enzyme involved in forming the formyl group at position 8 of the porphyrin ring YOR303W CPA1 Carbamoyl phosphate synthetase, arginine specific YJR109C CPA2 carbamyl phosphate synthetase YDR155C CPH1 cyclophilin peptidyl-prolyl cis-trans isomerase YML078W CPR3 cyclophilin-3 (cyclosporin-sensitive proline rotamase-3) YLR216C CPR6 acyclophilin related to the mammalian CyP-40; physically interacts with RPD3 gene product YOR259C CRL13 ATPase; component of the 26S proteasome cap subunit YGR218W CRM1 Chromosome region maintenance protein YCR031C CRY1 ribosomal protein rp59 YJL191W CRY2 Ribosomal protein CRY1 (rp59) (human S14) (rat S14) (CRY1 and CRY2 code for nearly identical proteins) YGL238W CSE1 Proteinrequired for accurate mitotic chromosome segregation YKL049C CSE4 high similarity to histone H3 and to human centromere protein CENP-A YDR256C CTA1 catalase A YKL139W CTK1 putativekinase subunit of the kinase complex that phosphorylates the RPO21 CTD (carboxy-terminal domain); also called CTDK-I alpha subunit YBR291C CTP1 citrate tranporter in mitochondrial inner membrane YGR088W CTT1 cytoplasmic catalase T YEL027W CUP5 Vacuolar ATP synthase 16 Kda proteolipid subunit; dicyclohexylcarbodiimide binding subunit YGL027C CWH41 anovel endoplasmic reticulum membrane N-glycoprotein involved in beta-1,6-glucan assembly YML054C CYB2 Cytochrome b2 [L--lactate cytochrome-c oxidoreductase] YJR048W CYC1 iso-1-cytochrome c YEL039C CYC7 iso-2-cytochrome c YGL103W CYH2 ribosomal protein gene YHR057C CYP2 Peptidylprolyl isomerase (cyclophilin) ER or secreted YDR304C CYP5 Cyclophilin D, Peptidyl-prolyl cis-trans isomerase D YAL012W CYS3 cystathionine gamma-lyase YGR155W CYS4 Cystathionine beta-synthase YOR065W CYT1 Cytochrome c1 YHR028C DAP2 Dipeptidyl aminopeptidase B (DPAP B) YPR111W DBF20 kinase required for late nuclear division YPL119C DBP1 putative ATP-dependent RNA helicase; Dead box protein YNL112W DBP2 ATP-dependent RNA helicase of DEAD box family YOR046C DBP5 RNA helicase YOR204W DED1 ATP-dependentRNA helicase of DEAD box family; suppressor of a pre-mRNA splicing mutation, prp8-1 YDL160C DHH1 PutativeRNA helicase of DEAD box family, required for Rap1p localization to telomeres YKL017C DIP1 DOM34Interacting Protein YER179W DMC1 Meiosis-specificprotein related to Rad51p and RecA and required for spore formation YHR164C DNA2 DNA replication helicase YOR005C DNL4 ATP dependent DNA ligase YLL001W DNM1 Dynamin-related protein YKL213C DOA1 requiredfor normal intracellular ubiquitin metabolism and for normal rates of proteolysis of ubiquitin-dependent proteolytic substrates in vivo YDR069C DOA4 ubiquitin isopeptidase YLL018C DPS1 Aspartyl-tRNA synthetase, cytosolic YLL008W DRS1 putative ATP dependent RNA helicase YAL026C DRS2 Membrane-spanning Ca-ATPase (P-type),member of the cation transport (E1-E2) ATPases YDL101C DUN1 protein kinase YBR208C DUR1,2 Urea amidolyase (contains urea carboxylase and allophanate hydrolase) YBR252W DUT1 dUTP pyrophosphatase (dUTPase) YKR054C DYN1 heavy chain of cytoplasmic dynein YHR068W DYS1 Deoxyhypusine synthase YEL030W ECM10 ExtraCellularMutant YHR132C ECM14 ExtraCellularMutant YMR128W ECM16 ExtraCellularMutant YHL030W ECM29 ExtraCellularMutant YLR299W ECM38 gamma-glutamyltransferase homolog YAL003W EFB1 Translation elongation factor EF-1beta, GDP/GTP exchange factor for Tef1p/Tef2p YOR133W EFT1 translation elongation factor 2 (EF-2) YDR385W EFT2 translation elongation factor 2 (EF-2) YLR083C EMP70 integral membrane protein; p24a protein YDR040C ENA1 plasma membrane protein; putative Na+ pump; P-type ATPase; Ca2+ ATPase YDR039C ENA2 plasma membrane protein; putative Na+ pump; P-type ATPase YDR038C ENA5 UNKNOWN YGR254W ENO1 enolase I YHR174W ENO2 enolase YBR247C ENP1 Putative 57 kDa protein with an apparent MW of 70 kDa by SDS-PAGE YBL040C ERD2 encodes the HDEL receptor required for retention of ER proteins YGR175C ERG1 Squalene monooxygenase YPL028W ERG10 acetoacetyl CoA thiolase YHR007C ERG11 cytochrome P450 lanosterol 14a-demethylase YJL167W ERG20 Farnesyl diphosphate synthetase (FPP synthetase) YNL280C ERG24 sterol C-14 reductase YGR060W ERG25 C-4 sterol methyl oxidase YLR056W ERG3 C-5 sterol desaturase YGL012W ERG4 Sterol C-24 reductase YHR072W ERG7 2,3-oxidosqualene-lanosterol cyclase YHR190W ERG9 squalene synthetase YOR393W ERR1 enolase homolog YGR029W ERV1 Proteinessential for mitochondrial biogenesis and cell viability YBR136W ESR1 Proteinrequired for mitotic growth, DNA repair and mitotic recombination YOR317W FAA1 long chain fatty acyl:CoA synthetase YER015W FAA2 Acyl-CoA synthetase (fatty acid activator 2) YIL009W FAA3 Acyl CoA synthase YMR246W FAA4 long-chain fatty acid--CoA ligase and synthetase 4 YBR041W FAT1 Fatty acid transporter YLR377C FBP1 fructose-1,6-bisphosphatase YJL155C FBP26 Fructose-2,6-biphosphatase YMR229C FMI1 GeneFacilitating the Mitochondrial Import of hydrophobic proteins YGR267C FOL2 GTP-cyclohydrolase I YKR009C FOX2 peroxisomal multifunctional beta-oxidation protein YNL135C FPR1 peptidylprolyl cis-trans isomerase YFL022C FRS2 Phenylalanyl-tRNA synthetase, beta subunit, cytoplasmic YJL221C FSP2 homology to maltase(alpha-D-glucosidase) YPL262W FUM1 mitochondrial and cytoplasmic fumarase (fumarate hydralase) YAL019W FUN30 Showshomology to SNF2 transcriptional regulator YAL017W FUN31 Containsserine/threonine protein kinase domain and shows homology with the SNF1 serine/threonine protein kinase YBL016W FUS3 cdc2+/CDC28 related kinase with positive role in conjugation YBR020W GAL1 galactokinase YBR019C GAL10 UDP-glucose 4-epimerase YDR009W GAL3 galactokinase YBR018C GAL7 galactose-1-phosphate uridyl transferase YER025W GCD11 gamma subunit of translational initiation factor eIF-2 YGR083C GCD2 translational repressor of GCN4 protein YDR211W GCD6 Translation initiation factor eIF-2B (a guanine nucleotide exchange factor) YLR291C GCD7 negative regulator of GCN4 expression YGL195W GCN1 translational activator of GCN4 through activation of GCN2 in response to starvation YKR026C GCN3 negative regulator of GCD12, thereby serving indirectly as a positive regulator of GCN4 YGR252W GCN5 positive regulator of GCN4 expression and activity of the HAP2--HAP3--HAP4 transcriptional activation complex YDR019C GCV1 glycine cleavage T protein (T subunit of glycine decarboxylase complex YOR120W GCY1 Similar to mammalian aldo/keto reductases YER136W GDI1 GDP dissociation inhibitor YJR040W GEF1 putative transport protein involved in intracellular iron metabolism YKL104C GFA1 Glutamine_fructose-6-phosphate amidotransferase (glucoseamine-6-phosphate synthase) YEL011W GLC3 1,4-glucan-6-(1,4-glucano)-transferase YER133W GLC7 protein phosphatase type I YCL040W GLK1 Glucokinase YPR035W GLN1 glutamine synthetase YOR168W GLN4 glutaminyl-tRNA synthetase YPL091W GLR1 Glutathione oxidoreductase YHR183W GND1 6-phosphogluconatedehydrogenase, decarboxylating; converts 6-phosphogluconate + NADP to ribulose-5-phosphate + NADPH + CO2 YGR256W GND2 6-phosphogluconate dehydrogenase YHR005C GPA1 alpha subunit of G protein coupled to mating factor receptors YER020W GPA2 nucleotide binding regulatory protein YDL022W GPD1 glycerol-3-phosphate dehydrogenase YOL059W GPD2 Glycerol-3-phosphate dehydrogenase (NAD+) YPR160W GPH1 Glycogen phosphorylase YKL152C GPM1 Phosphoglycerate mutase YLR075W GRC5 Ubiquinol-cytochrome C reductase complex subunit VI requiring protein YBR121C GRS1 Glycyl-tRNA synthase YJL101C GSH1 gamma-glutamylcysteine synthetase YOL049W GSH2 Glutathione Synthetase YLR293C GSP1 GTP-binding protein YOR185C GSP2 GTP-binding protein YFR015C GSY1 Glycogen synthase (UDP-gluocse--starch glucosyltransferase) YLR258W GSY2 Glycogen synthase (UDP-gluocse--starch glucosyltransferase) YML121W GTR1 putative GTP binding protein YMR217W GUA1 GMP synthase YDR454C GUK1 guanylate kinase YHL032C GUT1 glyerol kinase (converts glycerol to glycerol-3-phosphate YIL155C GUT2 glycerol-3-phosphate dehydrogenase, mitochondrial YBL021C HAP3 transcriptional activator protein of CYC1 YEL056W HAT2 subunit of a cytoplasmic histone acetyltransferase YKR084C HBS1 Proteinrelated to translation elongation factor EF-1alpha and to Suf12p/Sup2p/Gst1p/Sup35p YJL033W HCA4 putative RNA helicase YDR232W HEM1 5-aminolevulinate synthase YDR044W HEM13 Coproporphyrinogen III oxidase YOR176W HEM15 ferrochelatase (protoheme ferrolyase) YGL040C HEM2 delta-aminolevulinate dehydratase (porphobilinogen synthase) YDL205C HEM3 phorphobilinogen deaminase (uroporphyrinogen synthase), the third step in heme biosynthesis YMR207C HFA1 UNKNOWN YBR009C HHF1 Histone H4 (HHF1 and HHF2 code for identical proteins) YNL030W HHF2 Histone H4 (HHF1 and HHF2 code for identical proteins) YBR010W HHT1 Histone H3 (HHT1 and HHT2 code for identical proteins) YNL031C HHT2 Histone H3 (HHT1 and HHT2 code for identical proteins) YBL008W HIR1 putative repressor protein homologous to yeast Tup1p and mammalian retinal transducin; contains nuclear targeting signal YML075C HMG1 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase isozyme YLR450W HMG2 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase isozyme YBR034C HMT1 protein arginine methyltransferase (mono- and asymmetrically dimethylating enzyme) YLR113W HOG1 mitogen-activated protein kinase (MAP kinase) YOL123W HRP1 Putativepolyadenylated-RNA-binding protein located in nucleus; similar to vertebrate hnRNP A/B protein family YPL204W HRR25 casein kinase I isoform YMR186W HSC82 constitutively expressed heat shock protein YKL101W HSL1 Putative protein kinase homologous to S. pombe cdr1/nim1 YLL026W HSP104 heat shock protein 104 YLR259C HSP60 heat shock protein 60; chaperonin protein YDR258C HSP78 Mitochondrial heat shock protein 78 kDa YPL240C HSP82 heat shock protein YDR225W HTA1 Histone H2A (HTA1 and HTA2 code for nearly identical proteins) YBL003C HTA2 Histone H2A (HTA1 and HTA2 code for nearly identical proteins) YDR224C HTB1 Histone H2B (HTB1 and HTB2 code for nearly identical proteins) YBL002W HTB2 Histone H2B (HTB1 and HTB2 code for nearly identical proteins) YPR033C HTS1 cytoplasmic and mitochondrial histidine tRNA synthetases YOL012C HTZ1 An evolutionarily conserved member of the histone H2A F/Z family of histone variants YJR006W HUS2 Mayplay a role in DNA replication YFR053C HXK1 Hexokinase I (PI) (also called Hexokinase A) YGL253W HXK2 Hexokinase II (PII) (also called Hexokinase B) YEL034W HYP2 Translation initiation factor eIF-5A YNL037C IDH1 alpha-4-beta-4 subunit of mitochondrial isocitrate dehydrogenase 1 YPL117C IDI1 Isopentenyl diphosphate:dimethylallyl diphosphate isomerase (IPP isomerase) YDL066W IDP1 Mitochondrial form of NADP-specific isocitrate dehydrogenase YLR174W IDP2 Cytosolic form of NADP-dependent isocitrate dehydrogenase YNL009W IDP3 peroxisomal NADP-dependent isocitrate dehydrogenase YOL023W IFM1 mitochondrial initiation factor 2 YBL076C ILS1 cytoplasmic isoleucyl-tRNA synthetase YJL106W IME2 Homolog of the human core snRNP protein E; Serine/Threonine protein kinase YPL209C IPL1 Protein kinase YBR011C IPP1 Inorganic pyrophosphatase YPL040C ISM1 nuclear encoded mitochondrial isoleucyl-tRNA synthetase YBR017C KAP104 karyopherin beta 2, yeast transportin YLR347C KAP95 95 kDa structural and functional homolog of vertebrate karyopherin beta (importin 90) YJL034W KAR2 Homologue of mammalian BiP (GPR78) protein; member of the HSP70 gene family YPR141C KAR3 kinesin-like nuclear fusion protein YGL173C KEM1 strand exchange protein 1, 5'->3' exoribonuclease YNL238W KEX2 Ca2+-dependent serine protease YIL125W KGD1 alpha-ketoglutarate dehydrogenase YDR148C KGD2 dihydrolipoyl transsuccinylase component of alpha-ketoglutarate dehydrogenase complex in mitochondria YLR096W KIN2 Serine/threonine protein kinase YAR018C KIN3 protein kinase YOR233W KIN4 protein kinase YCR091W KIN82 Putative serine/threonine protein kinase most similar to cyclic nucleotide-dependent protein kinase subfamily and the protein kinase C subfamily YBL063W KIP1 kinesin related protein YPL155C KIP2 kinesin-related protein YGL216W KIP3 Kinesin-relatedprotein YLL019C KNS1 protein kinase homolog YDR037W KRS1 lysyl-tRNA synthetase YNL239W LAP3 Aminopeptidase of cysteine protease family YNL071W LAT1 Dihydrolipoamide acetyltransferase component (E2) of pyruvate dehydrogenase complex YDR062W LCB2 Probable component of serine palmitoyltransferase, which catalyzes the first step in biosynthesis of long-chain sphingolipids YFL018C LPD1 dihydrolipoamide dehydrogenase precursor (mature protein is the E3 component of alpha-ketoacid dehydrogenase complexes) YJL030W MAD2 putative calcium bindng protein YHR141C MAK18 Ribosomal protein RPL41 (YL27) (YP44) (human L36A) (rat L36A) (RPL41A and RPL41B code for identical proteins) YBR142W MAK5 Probablepre-mRNA splicing RNA-helicase of the DEAD box family YGR292W MAL1 UNKNOWN YBR299W MAL32 UNKNOWN YLR244C MAP1 methionine aminopeptidase YBL091C MAP2 methionine aminopeptidase 2 YLR163C MAS1 mitochondrial processing protease subunit YHR024C MAS2 53 kDa subunit of the mitochondrial processing protease YNL307C MCK1 43.1 kDa Serine/threonine/tyrosine protein kinase YBL023C MCM2 Memberof complex that acts at ARS's to initiate replication YEL032W MCM3 Memberof complex that acts at ARS's to initiate replication YKL085W MDH1 mitochondrial malate dehydrogenase YOL126C MDH2 cytosolic malate dehydrogenase YDL078C MDH3 malate dehydrogenase YLR188W MDL1 ATP-bindingcassette (ABC) transporter family member YPL270W MDL2 ATP-bindingcassette (ABC) transporter family member YLR069C MEF1 mitochondrial elongation factor G-like protein YJL102W MEF2 mitochondrial elongation factor G-like protein YGR264C MES1 methionyl tRNA synthetase YFR030W MET10 subunit of assimilatory sulfite reductase YKL001C MET14 adenylylsulfate kinase YLR303W MET17 O-Acetylhomoserine-O-Acetylserine Sulfhydralase YOR330C MIP1 catalytic subunit of mitochondrial DNA polymerase YJR077C MIR1 mitochondrial protein import receptor YBR084W MIS1 mitochondrial C1-tetrahydroflate synthase YOR231W MKK1 protein kinase YPL140C MKK2 protein kinase YMR167W MLH1 mutL homolog; mismatch repair protein YKR095W MLP1 myosin-like protein YJR131W MNS1 specific alpha-mannosidase YPL082C MOT1 putative helicase YFR004W MPR1 Similar to S. pombe PAD1 gene product YDL028C MPS1 Ser/Thr/Tyr (dual specificity) protein kinase YMR224C MRE11 Proteinrequired for double-strand break repair and meiotic recombination YDL079C MRK1 MDS1 related protein kinase YHR120W MSH1 mutS homolog involved in mitochondrial DNA repair YOL090W MSH2 mutS homolog involved in nuclear DNA repair YCR092C MSH3 mutS homolog YDR097C MSH6 Homologof the human GTBP protein, which has been shown to function as a heterodimer with the human MSH2 protein in DNA mispair recognition. YBR195C MSI1 p50 subunit of the yeast Chromatin Assembly Factor-I (CAF-I) negative regulator of ras-mediated cAMP induction; homologous to beta subunit of GTP-binding proteins YNL073W MSK1 mitochondrial lysine-tRNA synthetase YKL194C MST1 mitochondrial threonine-tRNA synthetase YGR007W MUQ1 choline phosphate cytidylyltransferase (also called phosphoethanolamine cytidylyltransferase or phosphocholine cytidylyltransferase) YNR043W MVD1 mevalonate pyrophosphate decarboxylase YHR023W MYO1 myosin class V, alpha-helical middle YOR326W MYO2 myosin-1 YKL129C MYO3 myosin I YAL029C MYO4 myosin YLR382C NAM2 mitochondrial leucyl tRNA synthetase YMR080C NAM7 putative helicase YGL091C NBP35 35 kDa nucleotide binding protein YHR042W NCP1 NADP-cytochrome P450 reductase YMR309C NIP1 ~100 kDa cytoplasmic protein YLR195C NMT1 N-myristoyl transferase YDL014W NOP1 nucleolar protein, homologous to mammalian fibrillarin YNL061W NOP2 90-kDa protein, located in nucleolus, that is homologous to a human proliferation-associated nucleolar protein, p120 YHR102W NRK1 N-richkinase 1 YKL068W NUP100 Nuclear pore complex protein homologous to Nup116p YMR047C NUP116 Nuclear pore complex protein that is member of GLFG repeat-containing family of nucleoporins and is highly homologous to Nup100p YGL055W OLE1 delta-9-fatty acid desaturase YJR073C OPI3 Methylene-fatty-acyl-phospholipid synthase (unsaturated phospholipid N-methyltransferase) YML065W ORC1 120-kDa (largest) subunit of origin recognition complex (ORC); shows homology to Cdc6p, Cdc18p, and Sir3p and to proteins from K. lactis, S. pombe, and humans YKL184W ORD1 Ornithine decarboxylase YAR044W OSH1 Shows homology to the human oxysterol binding protein (OSBP) YER165W PAB1 Poly(A) binding protein, cytoplasmic and nuclear YER129W PAK1 Possibleserine/threonine-specific protein kinase that activates mammalian p53 (tumor suppressor) expressed in yeast YKR002W PAP1 poly(A) polymerase YKL197C PAS1 putative ATPase YDR244W PAS10 69-kDa protein containing tetratricopeptide repeat (TPR) YDR142C PAS7 Member of beta-transducin-related (WD-40) protein family YNL329C PAS8 Member of the AAA-protein family that includes NSFp and PAS1p YJL128C PBS2 protein kinase homolg YBR295W PCA1 Putative P-type Cu(2+)-transporting ATPase YGR202C PCT1 phosphorylcholine transferase; or cholinephosphate cytidylyltransferase YER178W PDA1 alpha subunit of pyruvate dehydrogenase (E1 alpha) YBR221C PDB1 beta subunit of pyruvate dehydrogenase (E1 beta) YCL043C PDI1 protein disulfide isomerase YPL154C PEP4 proteinase A YJL053W PEP8 Vacuolar protein similar to mouse gene H58 YBL030C PET9 mitochondrial ADP/ATP translocator YGR240C PFK1 phosphofructokinase alpha subunit YMR205C PFK2 phosphofructokinase beta subunit YIL107C PFK26 6-Phosphofructose-2-kinase YBR196C PGI1 phoshoglucoisomerase YCR012W PGK1 3-phosphoglycerate kinase YKL127W PGM1 phosphoglycerate mutase YMR105C PGM2 Phosphoglucomutase YGR132C PHB1 Prohibitin YPL031C PHO85 negative transcriptional regulator, protein kinase homolog YNL106C PIE3 Phosphatidylinositol phosphate phosphatase YNL267W PIK1 Phosphatidylinositol 4-kinase YBL022C PIM1 mitochondrial ATP-dependent protease YPR113W PIS1 phosphatidylinositol synthase YPL203W PKA3 cAMP-dependent protein kinase catalytic subunit YBL105C PKC1 putative protein kinase YPL268W PLC1 phosphoinositide-specific phospholipase C YGL008C PMA1 plasma membrane H+-ATPase YPL036W PMA2 plasma membrane ATPase YGL006W PMC1 putative vacuolar Ca2+ ATPase YER003C PMI40 mannose-6-phosphate isomerase YGL167C PMR1 Ca++-Pump, ATPase YNL082W PMS1 DNA mismatch repair enzyme YML069W POB3 Binds to Pol1 protein YNL102W POL1 DNA polymerase I YNL262W POL2 DNA polymerase II YBR088C POL30 profilerating cell nuclear antigen YNR052C POP2 Proteinrequired for glucose repression YIL160C POT1 peroxisomal 3-oxoacyl CoA thiolase YGL205W POX1 fatty-acyl coenzyme A oxidase YHR026W PPA1 proteolipid protein of the proton ATPase YMR267W PPA2 mitochondrial inorganic pyrophosphatase YNR032W PPG1 Serine/threonineprotein phosphatase involved in glycogen accumulation YDL134C PPH21 serine-threonine protein phosphatase 2A YDL188C PPH22 serine-threonine protein phosphatase 2A YDR075W PPH3 protein phosphatase type 2A YPL179W PPQ1 protein phosphatase Q YGR123C PPT1 serine/threonine phosphatase YML016C PPZ1 serine-threonine phosphatase Z YDR436W PPZ2 serine-threonine phosphatase Z YCL057W PRD1 Saccharolysin (oligopeptidase yscD) YER012W PRE1 22.6 kDa proteasome subunit YOR362C PRE10 proteasome component YC1 (protease yscE subunit 1) YPR103W PRE2 proteasome subunit YJL001W PRE3 proteasomal subunit Pre3 YFR050C PRE4 proteasome subunit necessary for peptidyl glutamyl peptide hydrolyzing activity YMR314W PRE5 Proteasome subunit, alpha-type YOL038W PRE6 Proteasome subunit, alpha-type YBL041W PRE7 proteasome subunit YML092C PRE8 proteasome component Y7 YGR135W PRE9 proteasome component Y13 YIR008C PRI1 p48 polypeptide of DNA primase YKL045W PRI2 p58 polypeptide of DNA primase YOR323C PRO2 gamma-glutamyl phosphate reductase YKR086W PRP16 putative ATP-binding protein YNR011C PRP2 putative RNA-dependent ATPase YER013W PRP22 helicase-like protein YDR243C PRP28 ATP-dependent helicase homolog YBR237W PRP5 RNA helicase homolog YDL030W PRP9 RNA splicing factor YKL181W PRS1 ribose-phosphate pyrophosphokinase YER099C PRS2 ribose-phosphate pyrophosphokinase 2 YHL011C PRS3 ribose-phosphate pyrophosphokinase 3 YBL068W PRS4 ribose-phosphate pyrophosphokinase 4 YOR361C PRT1 translation initiation protein YMR308C PSE1 Proteinthat affects protein secretion (protein secretion enhancer) YER089C PTC2 Protein phosphatase type 2C YBL056W PTC3 protein phosphatase type 2C YOR157C PUP1 putative proteasome subunit YGR253C PUP2 putative proteasome subunit YER094C PUP3 UNKNOWN YHR216W PUR5 UNKNOWN YHR037W PUT2 delta-1-pyrroline-5-carboxylate dehydrogenase YLR196W PWP1 periodictryptophan protein YCR055C PWP2 EightWD-repeats with homology with G protein beta subunits flanked by nonhomologous N-terminal and C-terminal extensions YCR057C PWP2 EightWD-repeats with homology with G protein beta subunits flanked by nonhomologous N-terminal and C-terminal extensions YPL147W PXA1 PeroxisomalABC-transporter 1 YKL188C PXA2 peroxisomal ABC transporter 2 YGL062W PYC1 pyruvate carboxylase YBR218C PYC2 pyruvate carboxylase YDL103C QRI1 UNKNOWN YMR022W QRI8 ubiquitin conjugating enzyme YPL022W RAD1 UV endonuclease YBR114W RAD16 Nucleotideexcision repair protein with DNA helicase domain of Snf2p family YGR258C RAD2 Nucleotideexcision repair protein YJR035W RAD26 Proteinhomologous to Cockayne syndrome B gene ERCC6 YKL113C RAD27 42 kDa 5' to 3' exonuclease required for Okazaki fragment processing YER171W RAD3 DNAhelicase component of transcription factor b (yeast homolog of human TFIIH) YLR032W RAD5 putative ATPase/DNA helicase YNL250W RAD50 Coiled-coilprotein involved in recombinational repair YER095W RAD51 recA-like protein YML032C RAD52 Proteinrequired for recombination and repair of X-ray damage YGL163C RAD54 Proteinrequired for recombination and repair of X-ray damage YGL058W RAD6 Ubiquitinconjugating enzyme involved in an error-prone DNA-damage recovery pathway YDL090C RAM1 component of protein prenyltransferase YOR101W RAS1 ras proto-oncogene homolog YNL098C RAS2 ras proto-oncogene homolog YOR048C RAT1 RNA trafficking protein; transcription activator YGL158W RCK1 Serine/threonine protein kinase YLR248W RCK2 Serine/threonine protein kinase YBR073W RDH54 Putative helicase similar to RAD54 YOR207C RET1 second-largest subunit of RNA polymerase III YPL167C REV3 DNA polymerase YAR007C RFA1 single-stranded DNA binding protein, subunit of replication factor RF-A YOR217W RFC1 Subunit 1 of Replication Factor C; homologous to human RFC 140 kDa subunit YJR068W RFC2 Subunit 2 of Replication Factor C; homologous to human RFC 37 kDa subunit YNL290W RFC3 Subunit 3 of Replication Factor C; homologous to human RFC 36 kDa subunit YOL094C RFC4 Subunit 4 of Replication Factor C; homologous to human RFC 40 kDa subunit YBR087W RFC5 Subunit 5 of Replication Factor C; homologous to human RFC 38 kDa subunit YBL082C RHK1 Resistanceto Hansenula Killer 1, hypothetical F-458 protein YPR165W RHO1 GTP-bindingprotein of the rho subfamily of ras-like proteins YNL090W RHO2 GTP-bindingprotein of the rho subfamily of ras-like proteins YIL118W RHO3 ras homolog--GTP binding protein YKR055W RHO4 ras homolog--GTP binding protein YMR139W RIM11 protein kinase that phosphorylates the meiotic activator IME1 YFL033C RIM15 Protein kinase related to S. pombe cek1+ YEL024W RIP1 Rieske iron-sulfur protein of the mitochondrial cytochrome bc1 complex YOR095C RKI1 Ribose-5-phosphateketol-isomerase YMR061W RNA14 Proteinwith a role in mRNA stability and/or poly(A) tail length YER070W RNR1 ribonucleotide reductase YJL026W RNR2 small subunit of ribonucleotide reductase YIL066C RNR3 Ribonucleotide reductase (ribonucleoside-diphosphate reductase) large subunit YGR180C RNR4 ribonucleotidereductase, small subunit (alt) YGL171W ROK1 ATP-dependentRNA helicase YBR229C ROT2 Reversalof tor2 lethality YLR441C RP10A Ribosomalprotein analogous to rat S3A YML063W RP10B Ribosomalprotein analogous to rat S3A YNL069C RP23 Ribosomal protein YOL120C RP28A Ribosomal protein rp28 (rat L18) (RP28A and RP28B code for identical proteins) YNL301C RP28B Ribosomal protein rp28 (rat L18) YDR447C RP51B Ribosomal protein RP51B (rat S17) YOR341W RPA190 RNA polymerase I subunit 190 (alpha) YOR151C RPB2 RNA polymerase II subunit YIL021W RPB3 45 kDa subunit of RNA polymerase II YBR154C RPB5 25-kDa RNA polymerase subunit (common to polymerases I, II and III) YDR404C RPB7 dissociable subunit of RNA polymerase II YPR110C RPC40 RNA polymerase III (C) subunit YNL330C RPD3 Transcriptionmodifier YPL131W RPL1 Ribosomal protein RPL1 (YL3) (rat L5) YLR340W RPL10E 60S ribosomal protein P0 (L10E). YIL133C RPL13 UNKNOWN YLR029C RPL13A Ribosomal protein RPL13A (YL10A) (rat L15) YDR418W RPL15A Ribosomal protein RPL15 (YL15) (E. coli L11) (rat L12a) (RPL15A and RPL15B code for identical proteins) YEL054C RPL15B Ribosomal protein RPL15 (YL15) (E. coli L11) (rat L12b) (RPL15B and RPL15A code for identical proteins) YGR085C RPL16A large ribosomal subunit protein 16A YLR448W RPL16B ribosomal protein, large subunit YKL180W RPL17 UNKNOWN YBL087C RPL17A Ribosomal protein RPL17A (E. coli L14) (YL32) (rat L23) YER117W RPL17B UNKNOWN YOR312C RPL18A1 60S ribosomal protein L18A YBL027W RPL19A Ribosomal protein YL14 (rat L19) (rp33) (RPL19A and RPL19B code for identical genes) YBR084C-A RPL19B Ribosomal protein YL14 (rat L19) (rp33) (RPL19A and RPL19B code for identical genes) YOL127W RPL25 Ribosomal protein RPL25 (YL25) (E. coli L23) (rat L23a) YHR010W RPL27 probable 60S ribosomal protein L27 YDR471W RPL27B 60S ribosomal protein L27, identical to Yhr010p YBR031W RPL2A large ribosomal subunit protein 2A YDR012W RPL2B large ribosomal subunit protein L2B; highly similar to ribosomal protein L2A (Rpl2bp) YLR185W RPL35A 60S ribosomal protein YL35 YNL162W RPL41A Ribosomal protein RPL41 (YL27) (YP44) (human L36A) (rat L36A) (RPL41A and RPL41B code for identical proteins) YHL033C RPL4A Ribosomal protein RPL4A (rp6) (YL5) (human L7a) (mouse L7a) (rat L7a) (RPL4A and RPL4B code for nearly identical proteins) YLL045C RPL4B Ribosomal protein RPL4B (rp6) (YL5) (human L7a) (mouse L7a) (rat L7a) (RPL4A and RPL4B code for nearly identical proteins) YIL018W RPL5A UNKNOWN YFR031C-A RPL5B UNKNOWN YGL076C RPL6A Ribosomal protein YL8 YPL198W RPL6B Ribosomal protein YL8B YDL140C RPO21 RNA polymerase II large subunit YPR187W RPO26 subunit common to RNA polymerases I, II, and III YOR116C RPO31 RNA polymerase III large subunit YFL036W RPO41 mitochondrial RNA polymerase II YBR181C RPS10A 40S ribosomal gene product S10 YDR064W RPS13C 40S ribosomal protein of the S13P family YNL302C RPS16A Ribosomal protein RPS16 (rp55) (YS16A) (rat S19) (RPS16A and RPS16B code for nearly identical proteins) YOL121C RPS16B 40S ribosomal protein S19B YDR025W RPS18A ribosomal protein S18 YBR048W RPS18B ribosomal protein S18 YOL040C RPS21 Ribosomal protein RPS21 (rp52) (E. coli S19) (rat S15) (RIG protein) YJL190C RPS24A Ribosomal protein RPS24 YLR367W RPS24B Ribosomal protein RPS24 YER074W RPS24EA 40S ribosomal protein S24E (RP50) YIL069C RPS24EB 40S ribosomal protein S24E (RP50) YGL189C RPS26A UNKNOWN YER131W RPS26B UNKNOWN YKL156W RPS27A 40S ribosomal protein S27-1 YHR021C RPS27B 40S ribosomal protein S27-2 YGR118W RPS28A ribosomal protein S12 YPR132W RPS28B ribosomal protein S12 YNL178W RPS3 Ribosomal protein RPS3 (rp13) (YS3) (Mammalian S3) YOR096W RPS30 UNKNOWN YJR123W RPS5 ribosomal protein RPS5 (mammalian S5) (previously called rp14, S2 or YS8) YHR203C RPS7A Ribosomal protein RPS7A (YS6) (rp5) (Rat S4) (human S4) (RPS7A and RPS7B code for identical proteins YJR145C RPS7B Ribosomal protein RPS7B (YS6) (rp5) (Rat S4) (human S4) (RPS7A and RPS7B code for identical proteins) YBL072C RPS8A Ribosomal protein rp19 (YS9) (Mammalian S8) YER102W RPS8B UNKNOWN YOR001W RRP6 RibosomalRNA Processing YFR037C RSC8 Rsc8is the eighth largest subunit of RSC, a fifteen-protein chromatin remodeling complex and related to the Swi/snf Complex. YER125W RSP5 Suppressorof mutations in SPT3 YGR152C RSR1 GTP-bindingprotein of the ras superfamily involved in bud site selection YGL194C RTL1 putative deacetylase YOR014W RTS1 highcopy suppressor of rox3 and a multicopy suppressor of hsp60-ts alleles YDR129C SAC6 fibrim homolog (actin-filament bundling protein) YPL178W SAE1 Similarto human and Xenopus Cap binding protein 20 (CBP20) YER043C SAH1 putative S-adenosyl-L-homocysteine hydrolase YLR180W SAM1 S-adenosylmethionine synthetase YDR502C SAM2 S-adenosylmethionine synthetase YPL218W SAR1 GTP binding protein YHR205W SCH9 cAMP-dependent protein kinase homolog, suppressor of cdc25ts YGL011C SCL1 Proteasome subunit YC7alpha/Y8 (protease yscE subunit 7) YKL148C SDH1 flavoprotein subunit of succinate dehydrogenase YLL041C SDH2 Succinate dehydrogenase (ubiquinone) iron-sulfur protein subunit YBL050W SEC17 peripheral membrane protein required for vesicular transport between ER and Golgi YBR080C SEC18 cytoplasmic protein involved in protein transport between ER and Golgi YNL287W SEC21 non-clathrin coat protein involved in transport between ER and Golgi YPR181C SEC23 cytoplasmic GTPase-activating protein YDR238C SEC26 UNKNOWN YGL137W SEC27 UNKNOWN YFL005W SEC4 Ras-like small GTP-binding protein YFL045C SEC53 phosphomannomutase YLR378C SEC61 membrane component of ER protein translocation apparatus YDR170C SEC7 Involvedin protein transport within the Golgi apparatus YIL075C SEN3 involvedin tRNA processing YDR023W SES1 seryl-tRNA sythetase YDL168W SFA1 Long-chain alcohol dehydrogenase (glytathione-dependent formaldehyde dehydrogenase) YMR190C SGS1 similar to the E. coli RecQ 3' to 5' DNA helicase; interacts with Top3 using two-hybrid screen YPR161C SGV1 protein kinase homolog YBR263W SHM1 Serine hydroxymethyltransferase, mitochondrial YLR058C SHM2 serine hydroxymethyltransferase YLR197W SIK1 homology to microtubule binding proteins and to X90565_5.cds YOL004W SIN3 DNA binding protein involved in transcriptional regulation YNL007C SIS1 sit4 suppressor, dnaJ homolog YDL047W SIT4 SIT4suppress mutations in DBF2 YIL002C SJH1 Phosphatidylinositol phosphate phosphatase YLR398C SKI2 antiviral protein, putative helicase YDR328C SKP1 suppressorof kinetochore protein YMR216C SKY1 Serine Protein Kinase YHR030C SLT2 putative protein kinase YDR189W SLY1 Hydrophilicsuppressor of ypt1 involved in vesicle trafficking between ER and Golgi YFL008W SMC1 Coiled-coilprotein involved in chromosome structure or segregation YFR031C SMC2 nuclearprotein related to ScII (chicken), XCAPE (xenopus), and cut14 (S. pombe); involved in chromosome segregation and condensation. Interacts with OBSMC1 YJL074C SMC3 UNKNOWN YOL122C SMF1 Suppressorof mitochondrial matrix protease mutant YHR050W SMF2 Suppressorof mitochondrial matrix protease mutant YPR054W SMK1 Sporulation-specificMAP kinase required for completion of sporulation YMR165C SMP2 Proteinwhose deletion causes increased plasmid stability YOR290C SNF2 transcriptional regulator YGL115W SNF4 Proteininvolved in derepression of glucose-repressed genes YJR104C SOD1 Cu, Zn superoxide dismutase YHR008C SOD2 Manganese-containing superoxide dismutase YJR159W SOR1 sorbitol-induced sorbitol dehydrogenase YFL002C SPB4 ATP-dependent RNA helicase YPR069C SPE3 putrescine aminopropyltransferase (spermidine synthase) YPL153C SPK1 serine, threonine, and tyrosine protein kinase YKR031C SPO14 Phospholipase D YGR059W SPR3 asporulation-specific homologue of the yeast CDC3/10/11/12 family of bud neck microfilament genes and is regulated by ABFI YPL175W SPT14 N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein YER148W SPT15 TATA-binding protein (tfIId) YML010W SPT5 transcription factor YGR116W SPT6 transcription factor YIL033C SRA1 regulatory subunit of cAMP-dependent protein kinase YJL164C SRA3 putative catalytic subunit of cAMP-dependent protein kinase YNL189W SRP1 karyopherin alpha homolog of 60 kDa YDR292C SRP101 signal recognition particle receptor YNL138W SRV2 70-kDa adenylyl cyclase-associated protein YAL005C SSA1 Heat shock protein of HSP70 family, cytoplasmic YLL024C SSA2 member of 70 kDa heat shock protein family YBL075C SSA3 member of 70 kDa heat shock protein family YER103W SSA4 member of 70 kDa heat shock protein family YDL229W SSB1 Heat shock protein of HSP70 family, cytoplasmic YNL209W SSB2 Heat shock protein of HSP70 family, homolog of SSB1 YJR045C SSC1 Mitochondrial matrix protein involved in protein import; subunit of SceI endonuclease YPL106C SSE1 Member of the 70-kDa heat-shock protein family YBR169C SSE2 Member of the 70-kDa heat-shock protein family YBR283C SSH1 SEC61homolog involved in co-translational pathway of protein transport YNR031C SSK2 A MAP kinase kinase kinase; activator of Pbs2p YLR005W SSL1 UNKNOWN YIL143C SSL2 DNA helicase homolog; homolog of human XPBC YPL220W SSM1 homologueof the E- and Archebacterial L1 ribisomal protein of the 60S ribosomal subunit YGL135W SSM2 homologueof the E- and Archebacterial L1 ribisomal protein of the 60S ribosomal subunit YPL042C SSN3 a cyclin(SSN8)-dependent serine/threonine protein kinase YLR362W STE11 Ser/Thr protein kinase; MEKK homolog YHL007C STE20 putative serine/threonine protein kinase YLR389C STE23 UNKNOWN YOR212W STE4 beta subunit of G protein coupled to mating factor receptor YKL209C STE6 ABC transporter, glycoprotein, component of a-factor secretory pathway YDL159W STE7 MEK homolog YIL126W STH1 helicase related protein, snf2 homolog YOR027W STI1 heat shock protein YGL022W STT3 UNKNOWN YLR305C STT4 Phosphatidylinositol-4-kinase YMR054W STV1 vacuolar proton pumping ATPase--100 kDa subunit YPR086W SUA7 transcription factor TFIIB homolog YGL048C SUG1 ATPase YNL244C SUI1 translation factor YJR007W SUI2 Translationinitiation factor eIF-2 alpha subunit YPL237W SUI3 beta subunit of translation initiation factor eIF-2 YLR092W SUL2 high affinity sulfate permease YHR200W SUN1 proteasome subunit YER021W SUN2 proteasomesubunit YDR172W SUP35 putative translation factor YGL123W SUP44 ribosomal protein S4 YBR143C SUP45 Recessiveomnipotent suppressor YBR189W SUP46 Ribosomal protein SUP46/RPS13 (YS11A) (YP28) (E. coli S4) (rat S9) YJL176C SWI3 transcription factor YGR274C TAF145 Componentof the TAFII complex required for activated transcription YGL112C TAF60 UNKNOWN YLR354C TAL1 Transaldolase, enzyme in the pentose phosphate pathway YOR244W TAS1 Acetyltransferase in the SAS gene family YOR063W TCM1 ribosomal protein L3 YDR212W TCP1 chaperonin subunit alpha YJL052W TDH1 Glyceraldehyde-3-phosphate dehydrogenase 1 YJR009C TDH2 glyceraldehyde 3-phosphate dehydrogenase YGR192C TDH3 Glyceraldehyde-3-phosphate dehydrogenase 3 YPR080W TEF1 translational elongation factor EF-1 alpha YBR118W TEF2 translational elongation factor EF-1 alpha YKL081W TEF4 Translation elongation factor EF-1gamma YBL088C TEL1 putative phosphatidylinositol kinase YPL122C TFB2 TFIIH subunit Tfb2 YDL185W TFP1 catalytic subunit of the vacuolar H(+)ATPase YPL234C TFP3 16-kDa subunit C of vacuolar membrane H(+)-ATPase YKL140W TGL1 succinate dehydrogenase cytochrome b subunit YIL078W THS1 Threonyl-tRNA synthetase, cytoplasmic YKR059W TIF1 translation initiation factor YMR260C TIF11 Translation initiation factor eIFeIF--1A YJL138C TIF2 translation initiation factor YMR146C TIF34 p39 subunit of translation initiation factor eIF3 YPR041W TIF5 Translation initiation factor eIF-5 YDR457W TOM1 hect-domain-containingprotein, required for G2/M transition; similar to RSP5; contains motifs typical of protein kinases YOL006C TOP1 topoisomerase I YNL088W TOP2 topoisomerase II YLR234W TOP3 DNA Topoisomerase III YJR066W TOR1 phosphatidylinositol kinase homolog YKL203C TOR2 phosphatidylinositol kinase homolg YAL016W TPD3 protein phosphatase 2A regulatory subunit A YDR050C TPI1 triosephosphate isomerase YKL166C TPK3 cAMP-dependent protein kinase catalytic subunit YML028W TSA1 Thiol-specific antioxidant YML085C TUB1 alpha-tubulin YFL037W TUB2 beta-tubulin YML124C TUB3 alpha-tubulin YLR212C TUB4 gamma tubulin-like protein YGR185C TYS1 tyrosyl-tRNA synthetase, cytoplasmic YKL210W UBA1 ubiquitin activating enzyme YDR177W UBC1 ubiquitin-conjugating enzyme YDR092W UBC13 ubiquitin-conjugating enzyme YBR082C UBC4 ubiquitin-conjugating enzyme YDR059C UBC5 ubiquitin-conjugating enzyme YEL012W UBC8 ubiquitin-conjugating enzyme; ubiquitin-protein ligase YIL148W UBI1 ubiquitin YKR094C UBI2 ubiquitin YLR167W UBI3 ubiquitin YLL039C UBI4 ubiquitin YJL197W UBP12 ubiquitin carboxyl-terminal hydrolase YBR058C UBP14 Ubiquitin-specific protease YER144C UBP5 Putative Ubiquitin-specific protease YGR048W UFD1 ubiquitinfusion degradation protein YDL190C UFD2 ubiquitinfusion degradation protein YKL010C UFD4 UbiquitinFusion Degradation YGR019W UGA1 gamma-aminobutyrate (GABA) transaminase (4-aminobutyrate aminotransferase) YML021C UNG1 uracil DNA glycosylase YJL130C URA2 carbamoyl-phophate synthetase, aspartate transcarbamylase, and glutamine amidotransferase YEL021W URA3 orotidine-5'-phosphate decarboxylase YKL024C URA6 uridine-monophosphate kinase (uridylate kinase) YBL039C URA7 CTP synthase YJR103W URA8 CTP synthase YBR191W URP1 Ribosomal protein URP1 (rat L21) YHL015W URP2 UNKNOWN YDL058W USO1 Integrin analogue gene YGR094W VAS1 mitochondrial and cytoplasmic valyl-tRNA synthetase YBR127C VMA2 VacuolarH-ATPase regulatory subunit (subunit b), 60 kDa subunit of V1 sector YKL080W VMA5 Vacuolar H-ATPase hydrophilic subunit (subunit C) YLR447C VMA6 36 kDa subunit of the vacuolar H(+) ATPase YEL051W VMA8 UNKNOWN YOR270C VPH1 95 kDa protein required for assembly and activity of vacuolar H(+) ATPase YKR001C VPS1 putative GTP-binding protein; similar to mammalian Mx proteins YBR097W VPS15 protein kinase homolog YOR089C VPS21 putative GTP-binding protein YLR240W VPS34 phosphatidylinositol 3-kinase YJL154C VPS35 Proteininvolved in vacuolar sorting YPR173C VPS4 defectivein vacuolar protein sorting YDR080W VPS41 vacuolarprotein sorting YGL095C VPS45 Proteinof the Sec1p family essential for vacuolar protein sorting YJL141C YAK1 protein kinase YAL015C YAL015C UNKNOWN YAL036C YAL036C UNKNOWN YAR073W YAR073W UNKNOWN YAR075W YAR075W UNKNOWN YAR035W YAT1 Outer carnitine acetyltransferase, mitochondrial YBL037W YBL037W UNKNOWN YBL052C YBL052C UNKNOWN YBL064C YBL064C UNKNOWN YBL078C YBL078C UNKNOWN YBL092W YBL092W UNKNOWN YBL098W YBL098W UNKNOWN YBR006W YBR006W UNKNOWN YBR028C YBR028C UNKNOWN YBR079C YBR079C UNKNOWN YBR139W YBR139W UNKNOWN YBR149W YBR149W UNKNOWN YBR198C YBR198C UNKNOWN YBR220C YBR220C UNKNOWN YBR234C YBR234C UNKNOWN YBR235W YBR235W UNKNOWN YBR241C YBR241C UNKNOWN YBR245C YBR245C UNKNOWN YBR284W YBR284W UNKNOWN YBR296C YBR296C UNKNOWN YDR135C YCF1 Metalresistance protein with similarity to human cystic fibrosis protein CFTR and multidrug resistance proteins YHR135C YCK1 membrane-bound casein kinase I homolog YNL154C YCK2 membrane-bound casein kinase I homolog YER123W YCK3 plasma membrane-bound casein kinase I homolog YCL024W YCL024W UNKNOWN YCL059C YCL059C UNKNOWN YCR027C YCR027C UNKNOWN YCR063W YCR063W UNKNOWN YCR073C YCR073C UNKNOWN YNL064C YDJ1 yeast dnaJ homolog (nuclear envelope protein); heat shock protein YDL019C YDL019C UNKNOWN YDL031W YDL031W UNKNOWN YDL064W YDL064W UNKNOWN YDL070W YDL070W UNKNOWN YDL082W YDL082W UNKNOWN YDL083C YDL083C UNKNOWN YDL084W YDL084W UNKNOWN YDL097C YDL097C UNKNOWN YDL100C YDL100C UNKNOWN YDL145C YDL145C UNKNOWN YDL147W YDL147W UNKNOWN YDL201W YDL201W UNKNOWN YDL216C YDL216C UNKNOWN YDL225W YDL225W UNKNOWN YDL246C YDL246C UNKNOWN YDR002W YDR002W UNKNOWN YDR021W YDR021W UNKNOWN YDR047W YDR047W UNKNOWN YDR060W YDR060W UNKNOWN YDR091C YDR091C UNKNOWN YDR093W YDR093W UNKNOWN YDR107C YDR107C UNKNOWN YDR111C YDR111C UNKNOWN YDR190C YDR190C UNKNOWN YDR218C YDR218C UNKNOWN YDR280W YDR280W UNKNOWN YDR287W YDR287W UNKNOWN YDR331W YDR331W UNKNOWN YDR334W YDR334W UNKNOWN YDR341C YDR341C UNKNOWN YDR373W YDR373W UNKNOWN YDR450W YDR450W UNKNOWN YDR453C YDR453C UNKNOWN YDR456W YDR456W UNKNOWN YDR496C YDR496C UNKNOWN YDR516C YDR516C UNKNOWN YEL026W YEL026W UNKNOWN YEL029C YEL029C UNKNOWN YER005W YER005W UNKNOWN YER047C YER047C UNKNOWN YER053C YER053C UNKNOWN YER073W YER073W UNKNOWN YER081W YER081W UNKNOWN YER107C YER107C UNKNOWN YER166W YER166W UNKNOWN YFL054C YFL054C UNKNOWN YFR010W YFR010W UNKNOWN YFR024C YFR024C UNKNOWN YFR024C-A YFR024C-A UNKNOWN YFR038W YFR038W UNKNOWN YFR047C YFR047C UNKNOWN YFR051C YFR051C UNKNOWN YGL003C YGL003C UNKNOWN YGL014W YGL014W UNKNOWN YGL078C YGL078C UNKNOWN YGL087C YGL087C UNKNOWN YGL120C YGL120C UNKNOWN YGL125W YGL125W UNKNOWN YGL141W YGL141W UNKNOWN YGL142C YGL142C UNKNOWN YGL150C YGL150C UNKNOWN YGL201C YGL201C UNKNOWN YGL245W YGL245W UNKNOWN YGR034W YGR034W UNKNOWN YGR043C YGR043C UNKNOWN YGR103W YGR103W UNKNOWN YGR173W YGR173W UNKNOWN YGR207C YGR207C UNKNOWN YGR211W YGR211W UNKNOWN YGR231C YGR231C UNKNOWN YGR287C YGR287C UNKNOWN YJL059W YHC3 Homologof human CLN3 YDR301W YHH1 150 kD protein associated with polyadenylation factor 1 (PF I) YHL012W YHL012W UNKNOWN YHL035C YHL035C UNKNOWN YHR002W YHR002W UNKNOWN YHR011W YHR011W UNKNOWN YHR020W YHR020W UNKNOWN YHR027C YHR027C UNKNOWN YHR064C YHR064C UNKNOWN YHR065C YHR065C UNKNOWN YHR069C YHR069C UNKNOWN YHR073W YHR073W UNKNOWN YHR098C YHR098C UNKNOWN YHR104W YHR104W UNKNOWN YHR169W YHR169W UNKNOWN YHR204W YHR204W UNKNOWN YIL003W YIL003W UNKNOWN YIL048W YIL048W UNKNOWN YIL074C YIL074C UNKNOWN YIL094C YIL094C UNKNOWN YIL103W YIL103W UNKNOWN YIL109C YIL109C UNKNOWN YIL153W YIL153W UNKNOWN YIL172C YIL172C UNKNOWN YJL045W YJL045W UNKNOWN YJL050W YJL050W UNKNOWN YJL060W YJL060W UNKNOWN YJL068C YJL068C UNKNOWN YJL070C YJL070C UNKNOWN YJL177W YJL177W UNKNOWN YJL200C YJL200C UNKNOWN YJL216C YJL216C UNKNOWN YJR031C YJR031C UNKNOWN YJR036C YJR036C UNKNOWN YJR096W YJR096W UNKNOWN YJR105W YJR105W UNKNOWN YJR110W YJR110W UNKNOWN YJR119C YJR119C UNKNOWN YJR125C YJR125C UNKNOWN YKL029C YKL029C UNKNOWN YKL035W YKL035W UNKNOWN YKL056C YKL056C UNKNOWN YKL073W YKL073W UNKNOWN YKL078W YKL078W UNKNOWN YKL134C YKL134C UNKNOWN YKL161C YKL161C UNKNOWN YKL173W YKL173W UNKNOWN YKL179C YKL179C UNKNOWN YKL189W YKL189W UNKNOWN YKL215C YKL215C UNKNOWN YKR103W YKR103W UNKNOWN YKR104W YKR104W UNKNOWN YPL195W YKS4 putative alpha/gamma adaptin component of the membrane-associate clathrin assembly complex YGR261C YKS5 putative beta adaptin component of the membrane-associate clathrin assembly complex YLL013C YLL013C UNKNOWN YLL015W YLL015W UNKNOWN YLL034C YLL034C UNKNOWN YLL048C YLL048C UNKNOWN YLR034C YLR034C UNKNOWN YLR070C YLR070C UNKNOWN YLR086W YLR086W UNKNOWN YLR089C YLR089C UNKNOWN YLR106C YLR106C UNKNOWN YLR146C YLR146C UNKNOWN YLR186W YLR186W UNKNOWN YLR209C YLR209C UNKNOWN YLR222C YLR222C UNKNOWN YLR231C YLR231C UNKNOWN YLR262C YLR262C UNKNOWN YLR272C YLR272C UNKNOWN YLR344W YLR344W UNKNOWN YLR345W YLR345W UNKNOWN YLR369W YLR369W UNKNOWN YLR370C YLR370C UNKNOWN YLR410W YLR410W UNKNOWN YLR419W YLR419W UNKNOWN YLR429W YLR429W UNKNOWN YLR432W YLR432W UNKNOWN YPR024W YME1 Mitochondrialprotein of the CDC48/PAS1/SEC18 family of ATPases YML024W YML024W UNKNOWN YML026C YML026C UNKNOWN YML056C YML056C UNKNOWN YML073C YML073C UNKNOWN YML086C YML086C UNKNOWN YML125C YML125C UNKNOWN YML126C YML126C UNKNOWN YMR049C YMR049C UNKNOWN YMR084W YMR084W UNKNOWN YMR085W YMR085W UNKNOWN YMR109W YMR109W UNKNOWN YMR110C YMR110C UNKNOWN YMR121C YMR121C UNKNOWN YMR142C YMR142C UNKNOWN YMR143W YMR143W UNKNOWN YMR162C YMR162C UNKNOWN YMR189W YMR189W UNKNOWN YMR213W YMR213W UNKNOWN YMR242C YMR242C UNKNOWN YMR290C YMR290C UNKNOWN YMR304W YMR304W UNKNOWN YMR323W YMR323W UNKNOWN YKL067W YNK1 Nucleoside diphosphate kinase YNL023C YNL023C UNKNOWN YNL045W YNL045W UNKNOWN YNL049C YNL049C UNKNOWN YNL096C YNL096C UNKNOWN YNL161W YNL161W UNKNOWN YNL163C YNL163C UNKNOWN YNL180C YNL180C UNKNOWN YNL247W YNL247W UNKNOWN YNL275W YNL275W UNKNOWN YNL288W YNL288W UNKNOWN YNL325C YNL325C UNKNOWN YNR047W YNR047W UNKNOWN YNR053C YNR053C UNKNOWN YOL043C YOL043C UNKNOWN YOL061W YOL061W UNKNOWN YOL097C YOL097C UNKNOWN YOL100W YOL100W UNKNOWN YOL113W YOL113W UNKNOWN YOL128C YOL128C UNKNOWN YOL157C YOL157C UNKNOWN YGR281W YOR1 ABC transporter YOR109W YOR109W UNKNOWN YOR136W YOR136W UNKNOWN YOR142W YOR142W UNKNOWN YOR187W YOR187W UNKNOWN YOR191W YOR191W UNKNOWN YOR226C YOR226C UNKNOWN YOR241W YOR241W UNKNOWN YOR261C YOR261C UNKNOWN YOR304W YOR304W UNKNOWN YOR310C YOR310C UNKNOWN YOR339C YOR339C UNKNOWN YOR347C YOR347C UNKNOWN YOR356W YOR356W UNKNOWN YOR374W YOR374W UNKNOWN YKL126W YPK1 76.5 kDa Serine/threonine protein kinase with similarity to protein kinase C YMR104C YPK2 protein kinase YPL006W YPL006W UNKNOWN YPL017C YPL017C UNKNOWN YPL023C YPL023C UNKNOWN YPL051W YPL051W UNKNOWN YPL074W YPL074W UNKNOWN YPL079W YPL079W UNKNOWN YPL081W YPL081W UNKNOWN YPL090C YPL090C UNKNOWN YPL135W YPL135W UNKNOWN YPL141C YPL141C UNKNOWN YPL150W YPL150W UNKNOWN YPL152W YPL152W UNKNOWN YPL217C YPL217C UNKNOWN YPL235W YPL235W UNKNOWN YPL281C YPL281C UNKNOWN YPR004C YPR004C UNKNOWN YPR010C YPR010C UNKNOWN YPR029C YPR029C UNKNOWN YPR031W YPR031W UNKNOWN YPR068C YPR068C UNKNOWN YPR081C YPR081C UNKNOWN YPR088C YPR088C UNKNOWN YDR368W YPR1 homologousto the aldo-keto reductase protein family YPR102C YPR102C UNKNOWN YPR108W YPR108W UNKNOWN YPR120C YPR120C UNKNOWN YPR184W YPR184W UNKNOWN YFL038C YPT1 Ras-like GTP-binding protein; most similar to mammalian Rab1A protein YER031C YPT31 GTP-binding protein YGL210W YPT32 ras-like GTPase YKR014C YPT52 rab5-likeGTPase involved in vacuolar protein sorting and endocytosis YNL093W YPT53 rab5-likeGTPase involved in vacuolar protein sorting and endocytosis YML001W YPT7 GTP-bindingprotein of the rab family with a role in protein transport between endosome-like compartments YHR016C YSC84 UNKNOWN YLR277C YSH1 subunit of Polyadenylation factor I (PF I) YGR214W YST1 YeastS2 YLR048W YST2 YeastS2 YOR117W YTA1 Probable26S protease subunit and member of the CDC48/PAS1/SEC18 family of ATPases YMR089C YTA12 mitochondrial membrane ATPase of the CDC48/PAS1/SEC18 (AAA) family YDR394W YTA2 UNKNOWN YKL145W YTA3 UNKNOWN YDL007W YTA5 Probable26S protease subunit and member of CDC48/PAS1/SEC18 family of ATPases YGR270W YTA7 Memberof CDC48/PAS1/SEC18 family of ATPases YMR243C ZRC1 Zinc-and cadmium-resistance protein YGR285C ZUO1 Zuotin, putative Z-DNA binding protein YNL241C ZWF1 Glucose-6-phosphate dehydrogenase