URL: http://genome-www.stanford.edu/mammal/#orfs
DATA: p_80.dat
Botstein, D., Chervitz, S.A., and Cherry, J.M., (1997), "Yeast as a Model Organism", Science 277: 1259.
CONTACT: sac@genome.stanford.edu GENBANK UPDATE: 22 July 1997 586 unique yeast ORFs ORF NAME LOCUS PRODUCT/DESCRIPTION -------- ----- ---------------------------------------- YHR047C AAP1' arginine/alanine aminopeptidase YLR027C AAT2 aspartate aminotransferase, cytosolic YNR016C ACC1 acetyl-CoA carboxylase YLR304C ACO1 Aconitase, mitochondrial YFL039C ACT1 Actin YNL220W ADE12 adenylosuccinate synthetase YLR359W ADE13 Adenylosuccinate Lyase YLR028C ADE16 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR) transformylase/IMP cyclohydrolase YMR120C ADE17 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR) transformylase/IMP cyclohydrolase YGR204W ADE3 C1-5,6,7,8-tetrahydrofolate synthase YGL234W ADE5,7 glycinamide ribotide synthetase and aminoimidazole ribotide synthetase YGR061C ADE6 5'-phosphoribosylformyl glycinamidine synthetase YDR226W ADK1 cytosolic adenylate kinase YLR397C AFG2 homology to the CDC48 gene product YOR335C ALA1 Cytoplasmic alanyl-tRNA synthetase gene YMR170C ALD2 aldehyde dehydrogenase, (NAD(P)+), likely cytosolic YMR169C ALD3 similarityto aldehyde dehydrogenases (NAD(P)+) YPL061W ALD6 cytosolic aldehyde dehydrogenase YBR243C ALG7 UDP-N-acetyl-glucosamine-1-P transferase (GPT) YML035C AMD1 putative alpha-mannosidase YGL156W AMS1 vacuolar alpha mannosidase YKL157W APE2 aminopeptidase yscII YKL135C APL2 beta-adaptin, large subunit of clathrin associated protein YPL259C APM1 medium subunit of the clathrin-associated protein complex YDL192W ARF1 ADP-ribosylation factor YDL137W ARF2 ADP-ribosylation factor 2 YOL058W ARG1 arginosuccinate synthetase YHR018C ARG4 argininosuccinate lyase YHR129C ARP1 actin-relatedprotein of the dynactin complex YDL029W ARP2 actin-related protein YJR065C ARP3 actin-relatedgene YMR301C ATM1 mitochondrial ABC transporter protein YBL099W ATP1 mitochondrial F1F0-ATPase alpha subunit YJR121W ATP2 F(1)F(0)-ATPase complex beta subunit, mitochondrial YHR208W BAT1 Branched-Chain Amino Acid Transaminase YJR148W BAT2 Branched-Chain Amino Acid Transaminase YMR116C BEL1 G-betalike protein YPR176C BET2 Geranylgeranyltransferase Type II beta subunit YER177W BMH1 Homolog of mammalian 14-3-3 proteins YDR099W BMH2 Homolog of mammalian 14-3-3 proteins YLR438W CAR2 ornithine aminotransferase YLR175W CBF5 major low affinity 55 kDa Centromere/microtubule binding protein YDR270W CCC2 Copper-transportingP-type ATPase with similarity to human Menkes and Wilsons genes YIL142W CCT2 Cytoplasmicchaperonin of the Cct ring complex related to Tcp1p; subunit beta YJL014W CCT3 Cytoplasmic chaperonin subunit gamma YDL143W CCT4 mitochondrial adenine nucleotide carrier isoform, subunit delta YJR064W CCT5 subunit of chaperonin subunit epsilon YDR188W CCT6 Cytoplasmicchaperonin of the Cct ring complex (previously called TCP1 or TRiC), distantly related to Tcp1p and to Hsp60 YJL111W CCT7 Componentof Chaperonin Containing T-complex subunit seven YJL008C CCT8 Componentof Chaperonin Containing T-complex subunit eight YKL022C CDC16 potential metal-binding, nucleic acid-binding protein YAL038W CDC19 Pyruvate kinase YDL102W CDC2 large subunit of DNA polymerase III YOR074C CDC21 Thymidylate synthase YBR160W CDC28 protein kinase catalytic subunit YLR314C CDC3 Component of 10 nm filaments of mother-bud neck YLR229C CDC42 member of the Rho subfamily of Ras-like proteins YLR274W CDC46 Memberof complex that acts at ARS's to initiate replication YBR202W CDC47 Essentialfor initiation of DNA replication YDL126C CDC48 Microsomalprotein of CDC48/PAS1/SEC18 family of ATPases; full length homology to mammalian protein VCP; involved in secretion, peroxisome formation and gene expression YMR001C CDC5 protein kinase which functions at the G(sub)2/M boundary YDL132W CDC53 Celldivision cycle blocked at 36 degree C YPR019W CDC54 essentialfor initiation of DNA replication; homolog of S. pombe CDC21 YGL190C CDC55 Protein phosphatase 2A regulatory subunit B YDL164C CDC9 DNA ligase YBR029C CDS1 CDP-diacylglycerol synthase, CTP-phosphatidic acid cytidylyltransferase, CDP-diglyceride synthetase YGL206C CHC1 clathrin heavy chain YER164W CHD1 transcriptional regulator YPL008W CHL1 kinetochore protein in the DEAH box family YEL061C CIN8 Kinesin-relatedprotein involved in establishment and maintenance of mitotic spindle YIL035C CKA1 alpha subunit of casein kinase II YOR061W CKA2 alpha' subunit of casein kinase II YNL298W CLA4 protein kinase YML057W CMP2 catalytic A subunit of calcineurin YLR433C CNA1 Calcineurin subunit A; Protein phosphatase 2B catalytic subunit A1 YOR303W CPA1 Carbamoyl phosphate synthetase, arginine specific YJR109C CPA2 carbamyl phosphate synthetase YOR259C CRL13 ATPase; component of the 26S proteasome cap subunit YGR218W CRM1 Chromosome region maintenance protein YGL238W CSE1 Proteinrequired for accurate mitotic chromosome segregation YDR256C CTA1 catalase A YGR088W CTT1 cytoplasmic catalase T YAL012W CYS3 cystathionine gamma-lyase YGR155W CYS4 Cystathionine beta-synthase YOR065W CYT1 Cytochrome c1 YPL119C DBP1 putative ATP-dependent RNA helicase; Dead box protein YNL112W DBP2 ATP-dependent RNA helicase of DEAD box family YOR046C DBP5 RNA helicase YOR204W DED1 ATP-dependentRNA helicase of DEAD box family; suppressor of a pre-mRNA splicing mutation, prp8-1 YDL160C DHH1 PutativeRNA helicase of DEAD box family, required for Rap1p localization to telomeres YER179W DMC1 Meiosis-specificprotein related to Rad51p and RecA and required for spore formation YHR164C DNA2 DNA replication helicase YLL001W DNM1 Dynamin-related protein YLL018C DPS1 Aspartyl-tRNA synthetase, cytosolic YAL026C DRS2 Membrane-spanning Ca-ATPase (P-type),member of the cation transport (E1-E2) ATPases YBR208C DUR1,2 Urea amidolyase (contains urea carboxylase and allophanate hydrolase) YKR054C DYN1 heavy chain of cytoplasmic dynein YHR068W DYS1 Deoxyhypusine synthase YEL030W ECM10 ExtraCellularMutant YMR128W ECM16 ExtraCellularMutant YHL030W ECM29 ExtraCellularMutant YOR133W EFT1 translation elongation factor 2 (EF-2) YDR385W EFT2 translation elongation factor 2 (EF-2) YDR040C ENA1 plasma membrane protein; putative Na+ pump; P-type ATPase; Ca2+ ATPase YDR039C ENA2 plasma membrane protein; putative Na+ pump; P-type ATPase YDR038C ENA5 UNKNOWN YGR254W ENO1 enolase I YHR174W ENO2 enolase YGR175C ERG1 Squalene monooxygenase YPL028W ERG10 acetoacetyl CoA thiolase YHR007C ERG11 cytochrome P450 lanosterol 14a-demethylase YJL167W ERG20 Farnesyl diphosphate synthetase (FPP synthetase) YLR056W ERG3 C-5 sterol desaturase YHR072W ERG7 2,3-oxidosqualene-lanosterol cyclase YHR190W ERG9 squalene synthetase YOR393W ERR1 enolase homolog YBR136W ESR1 Proteinrequired for mitotic growth, DNA repair and mitotic recombination YLR377C FBP1 fructose-1,6-bisphosphatase YJL155C FBP26 Fructose-2,6-biphosphatase YMR229C FMI1 GeneFacilitating the Mitochondrial Import of hydrophobic proteins YGR267C FOL2 GTP-cyclohydrolase I YKR009C FOX2 peroxisomal multifunctional beta-oxidation protein YFL022C FRS2 Phenylalanyl-tRNA synthetase, beta subunit, cytoplasmic YPL262W FUM1 mitochondrial and cytoplasmic fumarase (fumarate hydralase) YAL019W FUN30 Showshomology to SNF2 transcriptional regulator YBL016W FUS3 cdc2+/CDC28 related kinase with positive role in conjugation YBR019C GAL10 UDP-glucose 4-epimerase YBR018C GAL7 galactose-1-phosphate uridyl transferase YER025W GCD11 gamma subunit of translational initiation factor eIF-2 YGL195W GCN1 translational activator of GCN4 through activation of GCN2 in response to starvation YER136W GDI1 GDP dissociation inhibitor YJR040W GEF1 putative transport protein involved in intracellular iron metabolism YKL104C GFA1 Glutamine_fructose-6-phosphate amidotransferase (glucoseamine-6-phosphate synthase) YEL011W GLC3 1,4-glucan-6-(1,4-glucano)-transferase YER133W GLC7 protein phosphatase type I YPR035W GLN1 glutamine synthetase YOR168W GLN4 glutaminyl-tRNA synthetase YPL091W GLR1 Glutathione oxidoreductase YHR183W GND1 6-phosphogluconatedehydrogenase, decarboxylating; converts 6-phosphogluconate + NADP to ribulose-5-phosphate + NADPH + CO2 YGR256W GND2 6-phosphogluconate dehydrogenase YHR005C GPA1 alpha subunit of G protein coupled to mating factor receptors YER020W GPA2 nucleotide binding regulatory protein YDL022W GPD1 glycerol-3-phosphate dehydrogenase YOL059W GPD2 Glycerol-3-phosphate dehydrogenase (NAD+) YPR160W GPH1 Glycogen phosphorylase YKL152C GPM1 Phosphoglycerate mutase YLR075W GRC5 Ubiquinol-cytochrome C reductase complex subunit VI requiring protein YBR121C GRS1 Glycyl-tRNA synthase YJL101C GSH1 gamma-glutamylcysteine synthetase YLR293C GSP1 GTP-binding protein YOR185C GSP2 GTP-binding protein YFR015C GSY1 Glycogen synthase (UDP-gluocse--starch glucosyltransferase) YLR258W GSY2 Glycogen synthase (UDP-gluocse--starch glucosyltransferase) YML121W GTR1 putative GTP binding protein YHL032C GUT1 glyerol kinase (converts glycerol to glycerol-3-phosphate YIL155C GUT2 glycerol-3-phosphate dehydrogenase, mitochondrial YEL056W HAT2 subunit of a cytoplasmic histone acetyltransferase YJL033W HCA4 putative RNA helicase YDR232W HEM1 5-aminolevulinate synthase YDR044W HEM13 Coproporphyrinogen III oxidase YOR176W HEM15 ferrochelatase (protoheme ferrolyase) YGL040C HEM2 delta-aminolevulinate dehydratase (porphobilinogen synthase) YMR207C HFA1 UNKNOWN YBR010W HHT1 Histone H3 (HHT1 and HHT2 code for identical proteins) YNL031C HHT2 Histone H3 (HHT1 and HHT2 code for identical proteins) YML075C HMG1 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase isozyme YLR450W HMG2 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase isozyme YBR034C HMT1 protein arginine methyltransferase (mono- and asymmetrically dimethylating enzyme) YLR113W HOG1 mitogen-activated protein kinase (MAP kinase) YPL204W HRR25 casein kinase I isoform YMR186W HSC82 constitutively expressed heat shock protein YLL026W HSP104 heat shock protein 104 YLR259C HSP60 heat shock protein 60; chaperonin protein YDR258C HSP78 Mitochondrial heat shock protein 78 kDa YPL240C HSP82 heat shock protein YPR033C HTS1 cytoplasmic and mitochondrial histidine tRNA synthetases YDL066W IDP1 Mitochondrial form of NADP-specific isocitrate dehydrogenase YLR174W IDP2 Cytosolic form of NADP-dependent isocitrate dehydrogenase YNL009W IDP3 peroxisomal NADP-dependent isocitrate dehydrogenase YOL023W IFM1 mitochondrial initiation factor 2 YBL076C ILS1 cytoplasmic isoleucyl-tRNA synthetase YPL209C IPL1 Protein kinase YBR011C IPP1 Inorganic pyrophosphatase YBR017C KAP104 karyopherin beta 2, yeast transportin YLR347C KAP95 95 kDa structural and functional homolog of vertebrate karyopherin beta (importin 90) YJL034W KAR2 Homologue of mammalian BiP (GPR78) protein; member of the HSP70 gene family YGL173C KEM1 strand exchange protein 1, 5'->3' exoribonuclease YNL238W KEX2 Ca2+-dependent serine protease YIL125W KGD1 alpha-ketoglutarate dehydrogenase YDR148C KGD2 dihydrolipoyl transsuccinylase component of alpha-ketoglutarate dehydrogenase complex in mitochondria YBL063W KIP1 kinesin related protein YLL019C KNS1 protein kinase homolog YDR037W KRS1 lysyl-tRNA synthetase YNL071W LAT1 Dihydrolipoamide acetyltransferase component (E2) of pyruvate dehydrogenase complex YDR062W LCB2 Probable component of serine palmitoyltransferase, which catalyzes the first step in biosynthesis of long-chain sphingolipids YFL018C LPD1 dihydrolipoamide dehydrogenase precursor (mature protein is the E3 component of alpha-ketoacid dehydrogenase complexes) YLR244C MAP1 methionine aminopeptidase YBL091C MAP2 methionine aminopeptidase 2 YLR163C MAS1 mitochondrial processing protease subunit YNL307C MCK1 43.1 kDa Serine/threonine/tyrosine protein kinase YBL023C MCM2 Memberof complex that acts at ARS's to initiate replication YEL032W MCM3 Memberof complex that acts at ARS's to initiate replication YKL085W MDH1 mitochondrial malate dehydrogenase YPL270W MDL2 ATP-bindingcassette (ABC) transporter family member YLR069C MEF1 mitochondrial elongation factor G-like protein YGR264C MES1 methionyl tRNA synthetase YOR330C MIP1 catalytic subunit of mitochondrial DNA polymerase YBR084W MIS1 mitochondrial C1-tetrahydroflate synthase YMR167W MLH1 mutL homolog; mismatch repair protein YFR004W MPR1 Similar to S. pombe PAD1 gene product YMR224C MRE11 Proteinrequired for double-strand break repair and meiotic recombination YOL090W MSH2 mutS homolog involved in nuclear DNA repair YCR092C MSH3 mutS homolog YDR097C MSH6 Homologof the human GTBP protein, which has been shown to function as a heterodimer with the human MSH2 protein in DNA mispair recognition. YKL194C MST1 mitochondrial threonine-tRNA synthetase YNR043W MVD1 mevalonate pyrophosphate decarboxylase YHR023W MYO1 myosin class V, alpha-helical middle YOR326W MYO2 myosin-1 YKL129C MYO3 myosin I YAL029C MYO4 myosin YLR382C NAM2 mitochondrial leucyl tRNA synthetase YMR080C NAM7 putative helicase YGL091C NBP35 35 kDa nucleotide binding protein YLR195C NMT1 N-myristoyl transferase YDL014W NOP1 nucleolar protein, homologous to mammalian fibrillarin YNL061W NOP2 90-kDa protein, located in nucleolus, that is homologous to a human proliferation-associated nucleolar protein, p120 YKL068W NUP100 Nuclear pore complex protein homologous to Nup116p YKL184W ORD1 Ornithine decarboxylase YER165W PAB1 Poly(A) binding protein, cytoplasmic and nuclear YKR002W PAP1 poly(A) polymerase YKL197C PAS1 putative ATPase YNL329C PAS8 Member of the AAA-protein family that includes NSFp and PAS1p YBR295W PCA1 Putative P-type Cu(2+)-transporting ATPase YER178W PDA1 alpha subunit of pyruvate dehydrogenase (E1 alpha) YBR221C PDB1 beta subunit of pyruvate dehydrogenase (E1 beta) YGR240C PFK1 phosphofructokinase alpha subunit YMR205C PFK2 phosphofructokinase beta subunit YBR196C PGI1 phoshoglucoisomerase YCR012W PGK1 3-phosphoglycerate kinase YKL127W PGM1 phosphoglycerate mutase YMR105C PGM2 Phosphoglucomutase YGR132C PHB1 Prohibitin YPL031C PHO85 negative transcriptional regulator, protein kinase homolog YNL106C PIE3 Phosphatidylinositol phosphate phosphatase YNL267W PIK1 Phosphatidylinositol 4-kinase YBL022C PIM1 mitochondrial ATP-dependent protease YPL203W PKA3 cAMP-dependent protein kinase catalytic subunit YBL105C PKC1 putative protein kinase YGL006W PMC1 putative vacuolar Ca2+ ATPase YGL167C PMR1 Ca++-Pump, ATPase YNL082W PMS1 DNA mismatch repair enzyme YNL102W POL1 DNA polymerase I YNL262W POL2 DNA polymerase II YIL160C POT1 peroxisomal 3-oxoacyl CoA thiolase YNR032W PPG1 Serine/threonineprotein phosphatase involved in glycogen accumulation YDL134C PPH21 serine-threonine protein phosphatase 2A YDL188C PPH22 serine-threonine protein phosphatase 2A YDR075W PPH3 protein phosphatase type 2A YPL179W PPQ1 protein phosphatase Q YGR123C PPT1 serine/threonine phosphatase YML016C PPZ1 serine-threonine phosphatase Z YDR436W PPZ2 serine-threonine phosphatase Z YCL057W PRD1 Saccharolysin (oligopeptidase yscD) YOR362C PRE10 proteasome component YC1 (protease yscE subunit 1) YPR103W PRE2 proteasome subunit YMR314W PRE5 Proteasome subunit, alpha-type YOL038W PRE6 Proteasome subunit, alpha-type YML092C PRE8 proteasome component Y7 YGR135W PRE9 proteasome component Y13 YOR323C PRO2 gamma-glutamyl phosphate reductase YKR086W PRP16 putative ATP-binding protein YNR011C PRP2 putative RNA-dependent ATPase YER013W PRP22 helicase-like protein YBR237W PRP5 RNA helicase homolog YKL181W PRS1 ribose-phosphate pyrophosphokinase YER099C PRS2 ribose-phosphate pyrophosphokinase 2 YHL011C PRS3 ribose-phosphate pyrophosphokinase 3 YBL068W PRS4 ribose-phosphate pyrophosphokinase 4 YOR361C PRT1 translation initiation protein YMR308C PSE1 Proteinthat affects protein secretion (protein secretion enhancer) YOR157C PUP1 putative proteasome subunit YGR253C PUP2 putative proteasome subunit YHR216W PUR5 UNKNOWN YHR037W PUT2 delta-1-pyrroline-5-carboxylate dehydrogenase YCR057C PWP2 EightWD-repeats with homology with G protein beta subunits flanked by nonhomologous N-terminal and C-terminal extensions YPL147W PXA1 PeroxisomalABC-transporter 1 YKL188C PXA2 peroxisomal ABC transporter 2 YGL062W PYC1 pyruvate carboxylase YBR218C PYC2 pyruvate carboxylase YDL103C QRI1 UNKNOWN YPL022W RAD1 UV endonuclease YBR114W RAD16 Nucleotideexcision repair protein with DNA helicase domain of Snf2p family YJR035W RAD26 Proteinhomologous to Cockayne syndrome B gene ERCC6 YKL113C RAD27 42 kDa 5' to 3' exonuclease required for Okazaki fragment processing YER171W RAD3 DNAhelicase component of transcription factor b (yeast homolog of human TFIIH) YNL250W RAD50 Coiled-coilprotein involved in recombinational repair YER095W RAD51 recA-like protein YGL163C RAD54 Proteinrequired for recombination and repair of X-ray damage YOR048C RAT1 RNA trafficking protein; transcription activator YBR073W RDH54 Putative helicase similar to RAD54 YOR207C RET1 second-largest subunit of RNA polymerase III YPL167C REV3 DNA polymerase YAR007C RFA1 single-stranded DNA binding protein, subunit of replication factor RF-A YOR217W RFC1 Subunit 1 of Replication Factor C; homologous to human RFC 140 kDa subunit YJR068W RFC2 Subunit 2 of Replication Factor C; homologous to human RFC 37 kDa subunit YNL290W RFC3 Subunit 3 of Replication Factor C; homologous to human RFC 36 kDa subunit YOL094C RFC4 Subunit 4 of Replication Factor C; homologous to human RFC 40 kDa subunit YBR087W RFC5 Subunit 5 of Replication Factor C; homologous to human RFC 38 kDa subunit YPR165W RHO1 GTP-bindingprotein of the rho subfamily of ras-like proteins YMR139W RIM11 protein kinase that phosphorylates the meiotic activator IME1 YER070W RNR1 ribonucleotide reductase YJL026W RNR2 small subunit of ribonucleotide reductase YIL066C RNR3 Ribonucleotide reductase (ribonucleoside-diphosphate reductase) large subunit YGR180C RNR4 ribonucleotidereductase, small subunit (alt) YBR229C ROT2 Reversalof tor2 lethality YLR441C RP10A Ribosomalprotein analogous to rat S3A YML063W RP10B Ribosomalprotein analogous to rat S3A YOR341W RPA190 RNA polymerase I subunit 190 (alpha) YOR151C RPB2 RNA polymerase II subunit YPR110C RPC40 RNA polymerase III (C) subunit YNL330C RPD3 Transcriptionmodifier YPL131W RPL1 Ribosomal protein RPL1 (YL3) (rat L5) YLR340W RPL10E 60S ribosomal protein P0 (L10E). YLR029C RPL13A Ribosomal protein RPL13A (YL10A) (rat L15) YGR085C RPL16A large ribosomal subunit protein 16A YBR031W RPL2A large ribosomal subunit protein 2A YDR012W RPL2B large ribosomal subunit protein L2B; highly similar to ribosomal protein L2A (Rpl2bp) YHL033C RPL4A Ribosomal protein RPL4A (rp6) (YL5) (human L7a) (mouse L7a) (rat L7a) (RPL4A and RPL4B code for nearly identical proteins) YLL045C RPL4B Ribosomal protein RPL4B (rp6) (YL5) (human L7a) (mouse L7a) (rat L7a) (RPL4A and RPL4B code for nearly identical proteins) YIL018W RPL5A UNKNOWN YFR031C-A RPL5B UNKNOWN YDL140C RPO21 RNA polymerase II large subunit YOR116C RPO31 RNA polymerase III large subunit YFL036W RPO41 mitochondrial RNA polymerase II YBR181C RPS10A 40S ribosomal gene product S10 YDR064W RPS13C 40S ribosomal protein of the S13P family YNL178W RPS3 Ribosomal protein RPS3 (rp13) (YS3) (Mammalian S3) YJR123W RPS5 ribosomal protein RPS5 (mammalian S5) (previously called rp14, S2 or YS8) YHR203C RPS7A Ribosomal protein RPS7A (YS6) (rp5) (Rat S4) (human S4) (RPS7A and RPS7B code for identical proteins YJR145C RPS7B Ribosomal protein RPS7B (YS6) (rp5) (Rat S4) (human S4) (RPS7A and RPS7B code for identical proteins) YER125W RSP5 Suppressorof mutations in SPT3 YGL194C RTL1 putative deacetylase YOR014W RTS1 highcopy suppressor of rox3 and a multicopy suppressor of hsp60-ts alleles YDR129C SAC6 fibrim homolog (actin-filament bundling protein) YER043C SAH1 putative S-adenosyl-L-homocysteine hydrolase YLR180W SAM1 S-adenosylmethionine synthetase YDR502C SAM2 S-adenosylmethionine synthetase YHR205W SCH9 cAMP-dependent protein kinase homolog, suppressor of cdc25ts YKL148C SDH1 flavoprotein subunit of succinate dehydrogenase YLL041C SDH2 Succinate dehydrogenase (ubiquinone) iron-sulfur protein subunit YBR080C SEC18 cytoplasmic protein involved in protein transport between ER and Golgi YNL287W SEC21 non-clathrin coat protein involved in transport between ER and Golgi YPR181C SEC23 cytoplasmic GTPase-activating protein YDR238C SEC26 UNKNOWN YGL137W SEC27 UNKNOWN YFL045C SEC53 phosphomannomutase YLR378C SEC61 membrane component of ER protein translocation apparatus YIL075C SEN3 involvedin tRNA processing YDR023W SES1 seryl-tRNA sythetase YDL168W SFA1 Long-chain alcohol dehydrogenase (glytathione-dependent formaldehyde dehydrogenase) YMR190C SGS1 similar to the E. coli RecQ 3' to 5' DNA helicase; interacts with Top3 using two-hybrid screen YBR263W SHM1 Serine hydroxymethyltransferase, mitochondrial YLR058C SHM2 serine hydroxymethyltransferase YLR197W SIK1 homology to microtubule binding proteins and to X90565_5.cds YOL004W SIN3 DNA binding protein involved in transcriptional regulation YDL047W SIT4 SIT4suppress mutations in DBF2 YLR398C SKI2 antiviral protein, putative helicase YMR216C SKY1 Serine Protein Kinase YHR030C SLT2 putative protein kinase YDR189W SLY1 Hydrophilicsuppressor of ypt1 involved in vesicle trafficking between ER and Golgi YFL008W SMC1 Coiled-coilprotein involved in chromosome structure or segregation YJL074C SMC3 UNKNOWN YMR165C SMP2 Proteinwhose deletion causes increased plasmid stability YOR290C SNF2 transcriptional regulator YJR159W SOR1 sorbitol-induced sorbitol dehydrogenase YPR069C SPE3 putrescine aminopropyltransferase (spermidine synthase) YKR031C SPO14 Phospholipase D YPL175W SPT14 N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein YER148W SPT15 TATA-binding protein (tfIId) YGR116W SPT6 transcription factor YJL164C SRA3 putative catalytic subunit of cAMP-dependent protein kinase YNL189W SRP1 karyopherin alpha homolog of 60 kDa YAL005C SSA1 Heat shock protein of HSP70 family, cytoplasmic YLL024C SSA2 member of 70 kDa heat shock protein family YBL075C SSA3 member of 70 kDa heat shock protein family YER103W SSA4 member of 70 kDa heat shock protein family YDL229W SSB1 Heat shock protein of HSP70 family, cytoplasmic YNL209W SSB2 Heat shock protein of HSP70 family, homolog of SSB1 YJR045C SSC1 Mitochondrial matrix protein involved in protein import; subunit of SceI endonuclease YPL106C SSE1 Member of the 70-kDa heat-shock protein family YBR169C SSE2 Member of the 70-kDa heat-shock protein family YLR005W SSL1 UNKNOWN YIL143C SSL2 DNA helicase homolog; homolog of human XPBC YHL007C STE20 putative serine/threonine protein kinase YLR389C STE23 UNKNOWN YKL209C STE6 ABC transporter, glycoprotein, component of a-factor secretory pathway YIL126W STH1 helicase related protein, snf2 homolog YOR027W STI1 heat shock protein YGL022W STT3 UNKNOWN YLR305C STT4 Phosphatidylinositol-4-kinase YMR054W STV1 vacuolar proton pumping ATPase--100 kDa subunit YGL048C SUG1 ATPase YJR007W SUI2 Translationinitiation factor eIF-2 alpha subunit YDR172W SUP35 putative translation factor YGL123W SUP44 ribosomal protein S4 YBR143C SUP45 Recessiveomnipotent suppressor YBR189W SUP46 Ribosomal protein SUP46/RPS13 (YS11A) (YP28) (E. coli S4) (rat S9) YLR354C TAL1 Transaldolase, enzyme in the pentose phosphate pathway YOR244W TAS1 Acetyltransferase in the SAS gene family YOR063W TCM1 ribosomal protein L3 YDR212W TCP1 chaperonin subunit alpha YJL052W TDH1 Glyceraldehyde-3-phosphate dehydrogenase 1 YJR009C TDH2 glyceraldehyde 3-phosphate dehydrogenase YGR192C TDH3 Glyceraldehyde-3-phosphate dehydrogenase 3 YPR080W TEF1 translational elongation factor EF-1 alpha YBR118W TEF2 translational elongation factor EF-1 alpha YBL088C TEL1 putative phosphatidylinositol kinase YPL122C TFB2 TFIIH subunit Tfb2 YDL185W TFP1 catalytic subunit of the vacuolar H(+)ATPase YIL078W THS1 Threonyl-tRNA synthetase, cytoplasmic YKR059W TIF1 translation initiation factor YJL138C TIF2 translation initiation factor YMR146C TIF34 p39 subunit of translation initiation factor eIF3 YDR457W TOM1 hect-domain-containingprotein, required for G2/M transition; similar to RSP5; contains motifs typical of protein kinases YOL006C TOP1 topoisomerase I YNL088W TOP2 topoisomerase II YLR234W TOP3 DNA Topoisomerase III YJR066W TOR1 phosphatidylinositol kinase homolog YKL203C TOR2 phosphatidylinositol kinase homolg YAL016W TPD3 protein phosphatase 2A regulatory subunit A YDR050C TPI1 triosephosphate isomerase YKL166C TPK3 cAMP-dependent protein kinase catalytic subunit YML028W TSA1 Thiol-specific antioxidant YML085C TUB1 alpha-tubulin YFL037W TUB2 beta-tubulin YML124C TUB3 alpha-tubulin YGR185C TYS1 tyrosyl-tRNA synthetase, cytoplasmic YKL210W UBA1 ubiquitin activating enzyme YBR082C UBC4 ubiquitin-conjugating enzyme YDR059C UBC5 ubiquitin-conjugating enzyme YLL039C UBI4 ubiquitin YJL197W UBP12 ubiquitin carboxyl-terminal hydrolase YKL010C UFD4 UbiquitinFusion Degradation YGR019W UGA1 gamma-aminobutyrate (GABA) transaminase (4-aminobutyrate aminotransferase) YJL130C URA2 carbamoyl-phophate synthetase, aspartate transcarbamylase, and glutamine amidotransferase YBL039C URA7 CTP synthase YJR103W URA8 CTP synthase YGR094W VAS1 mitochondrial and cytoplasmic valyl-tRNA synthetase YBR127C VMA2 VacuolarH-ATPase regulatory subunit (subunit b), 60 kDa subunit of V1 sector YLR447C VMA6 36 kDa subunit of the vacuolar H(+) ATPase YOR270C VPH1 95 kDa protein required for assembly and activity of vacuolar H(+) ATPase YKR001C VPS1 putative GTP-binding protein; similar to mammalian Mx proteins YBR097W VPS15 protein kinase homolog YLR240W VPS34 phosphatidylinositol 3-kinase YJL154C VPS35 Proteininvolved in vacuolar sorting YPR173C VPS4 defectivein vacuolar protein sorting YGL095C VPS45 Proteinof the Sec1p family essential for vacuolar protein sorting YAL036C YAL036C UNKNOWN YAR073W YAR073W UNKNOWN YBR006W YBR006W UNKNOWN YBR198C YBR198C UNKNOWN YBR220C YBR220C UNKNOWN YBR245C YBR245C UNKNOWN YDR135C YCF1 Metalresistance protein with similarity to human cystic fibrosis protein CFTR and multidrug resistance proteins YHR135C YCK1 membrane-bound casein kinase I homolog YNL154C YCK2 membrane-bound casein kinase I homolog YER123W YCK3 plasma membrane-bound casein kinase I homolog YCL059C YCL059C UNKNOWN YDL084W YDL084W UNKNOWN YDL097C YDL097C UNKNOWN YDL145C YDL145C UNKNOWN YDL147W YDL147W UNKNOWN YDL201W YDL201W UNKNOWN YDL246C YDL246C UNKNOWN YDR021W YDR021W UNKNOWN YDR047W YDR047W UNKNOWN YDR060W YDR060W UNKNOWN YDR091C YDR091C UNKNOWN YDR093W YDR093W UNKNOWN YDR111C YDR111C UNKNOWN YDR190C YDR190C UNKNOWN YDR331W YDR331W UNKNOWN YDR334W YDR334W UNKNOWN YDR373W YDR373W UNKNOWN YDR453C YDR453C UNKNOWN YER053C YER053C UNKNOWN YER073W YER073W UNKNOWN YER166W YER166W UNKNOWN YFR038W YFR038W UNKNOWN YFR047C YFR047C UNKNOWN YGL003C YGL003C UNKNOWN YGL120C YGL120C UNKNOWN YGL150C YGL150C UNKNOWN YGL201C YGL201C UNKNOWN YGL245W YGL245W UNKNOWN YGR043C YGR043C UNKNOWN YGR103W YGR103W UNKNOWN YGR173W YGR173W UNKNOWN YGR211W YGR211W UNKNOWN YGR231C YGR231C UNKNOWN YHL035C YHL035C UNKNOWN YHR020W YHR020W UNKNOWN YHR027C YHR027C UNKNOWN YHR204W YHR204W UNKNOWN YIL048W YIL048W UNKNOWN YIL103W YIL103W UNKNOWN YJL045W YJL045W UNKNOWN YJL050W YJL050W UNKNOWN YJL200C YJL200C UNKNOWN YKL035W YKL035W UNKNOWN YKL078W YKL078W UNKNOWN YKL173W YKL173W UNKNOWN YKL215C YKL215C UNKNOWN YKR103W YKR103W UNKNOWN YLL013C YLL013C UNKNOWN YLL015W YLL015W UNKNOWN YLL034C YLL034C UNKNOWN YLL048C YLL048C UNKNOWN YLR070C YLR070C UNKNOWN YLR089C YLR089C UNKNOWN YLR106C YLR106C UNKNOWN YLR209C YLR209C UNKNOWN YLR231C YLR231C UNKNOWN YLR262C YLR262C UNKNOWN YLR272C YLR272C UNKNOWN YLR369W YLR369W UNKNOWN YLR410W YLR410W UNKNOWN YLR432W YLR432W UNKNOWN YML056C YML056C UNKNOWN YML126C YML126C UNKNOWN YMR049C YMR049C UNKNOWN YMR085W YMR085W UNKNOWN YMR109W YMR109W UNKNOWN YMR121C YMR121C UNKNOWN YMR162C YMR162C UNKNOWN YMR189W YMR189W UNKNOWN YMR290C YMR290C UNKNOWN YMR304W YMR304W UNKNOWN YMR323W YMR323W UNKNOWN YNL045W YNL045W UNKNOWN YNL161W YNL161W UNKNOWN YNL163C YNL163C UNKNOWN YNL247W YNL247W UNKNOWN YNL288W YNL288W UNKNOWN YNL325C YNL325C UNKNOWN YNR053C YNR053C UNKNOWN YOL061W YOL061W UNKNOWN YOL097C YOL097C UNKNOWN YOL113W YOL113W UNKNOWN YGR281W YOR1 ABC transporter YOR109W YOR109W UNKNOWN YOR136W YOR136W UNKNOWN YOR142W YOR142W UNKNOWN YOR187W YOR187W UNKNOWN YOR241W YOR241W UNKNOWN YOR261C YOR261C UNKNOWN YOR304W YOR304W UNKNOWN YOR310C YOR310C UNKNOWN YOR347C YOR347C UNKNOWN YOR356W YOR356W UNKNOWN YOR374W YOR374W UNKNOWN YKL126W YPK1 76.5 kDa Serine/threonine protein kinase with similarity to protein kinase C YMR104C YPK2 protein kinase YPL006W YPL006W UNKNOWN YPL081W YPL081W UNKNOWN YPL090C YPL090C UNKNOWN YPL217C YPL217C UNKNOWN YPL235W YPL235W UNKNOWN YPL281C YPL281C UNKNOWN YPR004C YPR004C UNKNOWN YPR010C YPR010C UNKNOWN YPR081C YPR081C UNKNOWN YPR088C YPR088C UNKNOWN YPR102C YPR102C UNKNOWN YPR184W YPR184W UNKNOWN YFL038C YPT1 Ras-like GTP-binding protein; most similar to mammalian Rab1A protein YER031C YPT31 GTP-binding protein YGL210W YPT32 ras-like GTPase YLR277C YSH1 subunit of Polyadenylation factor I (PF I) YGR214W YST1 YeastS2 YLR048W YST2 YeastS2 YOR117W YTA1 Probable26S protease subunit and member of the CDC48/PAS1/SEC18 family of ATPases YDR394W YTA2 UNKNOWN YKL145W YTA3 UNKNOWN YDL007W YTA5 Probable26S protease subunit and member of CDC48/PAS1/SEC18 family of ATPases YNL241C ZWF1 Glucose-6-phosphate dehydrogenase