Wei Wang (1), wwang@genome.stanford.edu

J. Michael Cherry (1), cherry@genome.stanford.edu

David. Botstein* (1), botstein@genome.stanford.edu

Hao Li* (2), haoli@phy.ucsf.edu

(1) Department of Genetics, Stanford University, Stanford, CA 94305-5120

(2) Department of Biochemistry and Biophysics, University of California at San Francisco, San Francisco, CA 94143-0448

* corresponding authors