Figure3: Intrinsic genes in peripheral blood mononuclear cells.

(a) Global gene expression was measured in PBMCs from 16 individuals who were each sampled more than once over the course of one month. Also included are three patients sampled only once (gray branches). Genes displayed are those with the greatest degree of intrinsic-ness, i.e. those with intrinsic scores greater than 2 standard deviations from the mean (see text). The expression pattern of the corresponding ~340 genes is displayed in hierarchical cluster format. Gender is represented by colored branches: blue for male and pink for female. Blue and pink brackets represent samples from the same patient that clustered together. The other colored branches are patient samples that did not cluster together. (b) DDX17 gene expression ratio (log2) for up to 6 samples collected over the course of a month for 20 patients.