Rap1 Sir2 Sir3 Sir4 Control BIN Frequency Bin Frequency BIN Frequency Bin Frequency Bin Frequency 0% 0 0% 0 0% 0 0% 0 0% 0 1% 10 1% 26 1% 20 1% 19 1% 40 2% 18 2% 50 2% 23 2% 49 2% 44 3% 49 3% 52 3% 45 3% 42 3% 56 4% 30 4% 66 4% 56 4% 49 4% 63 5% 41 5% 66 5% 55 5% 86 5% 59 6% 47 6% 80 6% 64 6% 69 6% 87 7% 58 7% 95 7% 74 7% 64 7% 95 8% 54 8% 94 8% 86 8% 98 8% 87 9% 76 9% 90 9% 75 9% 95 9% 91 10% 57 10% 90 10% 84 10% 93 10% 89 11% 81 11% 92 11% 88 11% 91 11% 85 12% 90 12% 102 12% 102 12% 114 12% 102 13% 93 13% 91 13% 109 13% 106 13% 113 14% 85 14% 103 14% 106 14% 112 14% 108 15% 108 15% 102 15% 130 15% 110 15% 119 16% 114 16% 124 16% 146 16% 116 16% 117 17% 126 17% 105 17% 124 17% 125 17% 118 18% 122 18% 112 18% 114 18% 129 18% 141 19% 115 19% 116 19% 130 19% 119 19% 122 20% 136 20% 129 20% 146 20% 139 20% 113 21% 145 21% 134 21% 117 21% 129 21% 137 22% 125 22% 130 22% 147 22% 127 22% 112 23% 138 23% 121 23% 148 23% 122 23% 145 24% 150 24% 136 24% 129 24% 142 24% 130 25% 137 25% 132 25% 171 25% 127 25% 140 26% 164 26% 136 26% 122 26% 122 26% 135 27% 145 27% 127 27% 156 27% 137 27% 137 28% 163 28% 130 28% 137 28% 128 28% 148 29% 150 29% 144 29% 129 29% 154 29% 139 30% 190 30% 134 30% 160 30% 158 30% 157 31% 168 31% 158 31% 160 31% 146 31% 145 32% 175 32% 171 32% 148 32% 150 32% 146 33% 171 33% 146 33% 139 33% 153 33% 145 34% 183 34% 139 34% 159 34% 169 34% 175 35% 171 35% 149 35% 155 35% 151 35% 162 36% 161 36% 161 36% 163 36% 161 36% 159 37% 179 37% 155 37% 169 37% 169 37% 191 38% 199 38% 143 38% 148 38% 158 38% 163 39% 168 39% 133 39% 168 39% 177 39% 154 40% 198 40% 144 40% 155 40% 164 40% 170 41% 197 41% 152 41% 149 41% 157 41% 174 42% 198 42% 151 42% 175 42% 162 42% 203 43% 184 43% 157 43% 148 43% 164 43% 186 44% 181 44% 166 44% 177 44% 149 44% 147 45% 196 45% 165 45% 151 45% 172 45% 192 46% 196 46% 179 46% 167 46% 172 46% 160 47% 168 47% 148 47% 174 47% 177 47% 155 48% 174 48% 172 48% 161 48% 171 48% 151 49% 207 49% 187 49% 177 49% 175 49% 158 50% 177 50% 162 50% 171 50% 178 50% 174 51% 172 51% 172 51% 171 51% 182 51% 171 52% 190 52% 163 52% 160 52% 178 52% 157 53% 191 53% 174 53% 171 53% 154 53% 160 54% 164 54% 177 54% 183 54% 175 54% 167 55% 184 55% 169 55% 171 55% 155 55% 174 56% 184 56% 169 56% 156 56% 177 56% 167 57% 160 57% 165 57% 157 57% 184 57% 147 58% 200 58% 164 58% 160 58% 166 58% 132 59% 168 59% 174 59% 142 59% 174 59% 145 60% 177 60% 168 60% 152 60% 152 60% 155 61% 172 61% 173 61% 145 61% 155 61% 162 62% 138 62% 143 62% 174 62% 173 62% 132 63% 143 63% 155 63% 164 63% 167 63% 157 64% 172 64% 158 64% 150 64% 156 64% 158 65% 165 65% 139 65% 152 65% 143 65% 144 66% 132 66% 162 66% 167 66% 177 66% 143 67% 159 67% 150 67% 145 67% 165 67% 172 68% 153 68% 141 68% 157 68% 148 68% 148 69% 151 69% 148 69% 154 69% 148 69% 146 70% 132 70% 132 70% 162 70% 129 70% 134 71% 135 71% 145 71% 137 71% 152 71% 152 72% 124 72% 146 72% 149 72% 139 72% 121 73% 126 73% 140 73% 151 73% 151 73% 133 74% 112 74% 132 74% 130 74% 144 74% 139 75% 120 75% 155 75% 117 75% 121 75% 129 76% 107 76% 147 76% 138 76% 132 76% 123 77% 98 77% 138 77% 143 77% 134 77% 124 78% 94 78% 135 78% 135 78% 143 78% 139 79% 86 79% 131 79% 117 79% 135 79% 122 80% 112 80% 136 80% 121 80% 117 80% 129 81% 78 81% 127 81% 117 81% 103 81% 123 82% 87 82% 129 82% 111 82% 110 82% 117 83% 87 83% 114 83% 123 83% 93 83% 119 84% 84 84% 112 84% 96 84% 114 84% 104 85% 79 85% 126 85% 109 85% 113 85% 124 86% 81 86% 111 86% 111 86% 108 86% 114 87% 79 87% 100 87% 95 87% 110 87% 116 88% 67 88% 104 88% 93 88% 113 88% 111 89% 58 89% 95 89% 91 89% 101 89% 96 90% 69 90% 79 90% 112 90% 84 90% 104 91% 55 91% 89 91% 94 91% 72 91% 94 92% 81 92% 80 92% 81 92% 78 92% 83 93% 77 93% 78 93% 73 93% 54 93% 91 94% 84 94% 70 94% 76 94% 53 94% 84 95% 111 95% 66 95% 58 95% 51 95% 88 96% 98 96% 63 96% 60 96% 45 96% 57 97% 116 97% 46 97% 58 97% 40 97% 70 98% 124 98% 49 98% 55 98% 30 98% 50 99% 119 99% 66 99% 38 99% 43 99% 39 100% 111 100% 109 100% 77 100% 94 100% 15