ORF Gene Copies/cell t1/2 (min) mRNAs/hr Txn Rate %tile Rank Ribosomal? RAP1 Target? RAP1 ORF %tile Rnk Promoter1 Promoter2 P1 RAP1 %tile Rnk P2 RAP1 %tile Rnk . ORF CNTL Val P1 CNTL %tile Rnk P2 CNTL %tile Rnk Desc YNL145W MFA2 36 5 282.7 1 0.067054358 iYNL146W 0.332552172 0.011843377 0.174347406 "MFA2 -- mating -- Mating pheromone a-factor, nearly identical to a-factor encoded by MFA1, exported from the cell by Ste6p" YGL189C RPS26A 76.1 14 208.4 0.9998 1 1 0.885964513 iYGL189C 0.983275148 0.645182082 0.610620496 "RPS26A -- protein synthesis -- Ribosomal protein S26 (rat S26), nearly identical to Rps26Bp" YBR191W RPL21A 64.7 12 202.4 0.9996 1 0.972012214 0.975146199 "RPL21A -- protein synthesis -- Ribosomal protein L21 (rat L21), nearly identical to Rpl21Bp" YPL079W RPL21B 85.7 16 201.6 0.9994 1 1 0.915109144 iYPL080C 0.965890967 0.887390263 0.473357792 "RPL21B -- protein synthesis -- Ribosomal protein L21 (rat L21), nearly identical to Rpl21Ap" YHR021C RPS27B 65.6 13 192.4 0.9992 1 1 0.954280116 iYHR021C 0.975392559 0.746331237 0.337306202 "RPS27B -- protein synthesis -- Ribosomal protein S27 (yeast S27rp61YS20mammalian S27), nearly identical to Rps27Ap" YGR192C TDH3 89 18 188.1 0.999 1 0.941253994 iYGR192C 0.92473861 0.981887589 0.592117173 "TDH3 -- glycolysis -- Glyceraldehyde-3-phosphate dehydrogenase 3, converts D-glyceraldehyde 3-phosphate to 1,3-dephosphoglycerate" YLR110C YLR110C 81.6 16 183.5 0.9988 1 0.927300964 iYLR110C 0.910306302 0.4867111 0.321599115 "YLR110C -- unknown -- Cell wall manno similarity to Flo1p, Fig2p, Flo5p, Yal063p, and Ykr102p" YGL031C RPL24A 50.1 11 175.3 0.9986 1 1 0.927102758 iYGL031C IntYGL033W 0.986535535 0.484832874 0.879127838 0.815923207 0.422173566 "RPL24A -- protein synthesis -- Ribosomal protein L24A (yeast L30rp29YL21rat L24), nearly identical to Rpl24Bp" YGR118W RPS23A 52.9 11.5 173.7 0.9984 1 1 0.972694824 iYGR117C 0.959779417 0.973765432 0.00489229 "RPS23A -- protein synthesis -- Ribosomal protein S23 (yeast S28rp37YS14E. coli S12rat S23), identical to Rps23Bp" YFR031C-A RPL2A 56 12 172.1 0.9982 1 1 0.949338187 iYFR031C-A 0.969026628 0.955712788 0.126645895 RPL2A -- protein synthesis -- Ribosomal protein L2 (Yeast L5YL6rp8E. coli L2tobacco L2rat L8) YKL060C FBA1 74.1 16 167.9 0.998 0.953112516 iYKL060C 0.646653647 0.965805718 0.278021442 "FBA1 -- glycolysis -- Fructose-bisphosphate aldolase II, sixth step in glycolysis" YIL018W RPL2B 54.9 12 164.4 0.9978 1 1 0.97780263 iYIL019W 0.997316274 0.941437445 0.069866696 RPL2B -- protein synthesis -- Ribosomal protein L2 (yeast L5YL6rp8E. coli L2tobacco L2rat L8) YGR148C RPL24B 55.8 13 163.7 0.9976 1 1 0.93263124 iYGR148C 0.97676142 0.643256464 0.385214623 "RPL24B -- protein synthesis -- Ribosomal protein L24B (yeast L30rp29YL21rat L24), nearly identical to Rpl24Ap" YER102W RPS8B 47.3 11 162.7 0.9974 1 1 0.964208383 iYER101C 0.96463574 0.968863435 0.565535431 "RPS8B -- protein synthesis -- Ribosomal protein S8 (yeast S14YS9rp19mammalian S8), identical to Rps8Ap" YBL072C RPS8A 53.7 12 160 0.9972 1 1 0.954583848 iYBL072C 0.972994376 0.92496157 0.550375091 "RPS8A -- protein synthesis -- Ribosomal protein S8 (yeast S14YS9rp19mammalian S8), identical to Rps8Bp" YJL136C RPS21B 54.1 13 156.6 0.997 1 1 0.945433013 iYJL136C 0.991247823 0.854035639 0.297621986 "RPS21B -- protein synthesis -- Ribosomal protein S21 (yeast S26YS25rat S21), identical to Rps21Ap" YKL097W-A CWP2 71.6 17 153.9 0.9968 "CWP2 -- -- Mannocell wall, member of PAU1 family" YKR057W RPS21A 63 15 152.9 0.9964 1 1 0.933711948 iYKR056W 0.928363283 0.97677063 0.672865124 "RPS21A -- protein synthesis -- Ribosomal protein S21 (yeast S26YS25rat S21), identical to Rps21Bp" YDL229W SSB1 44.3 11 152.9 0.9964 1 0.652156158 iYDL230W 0.926610881 0.507519432 0.704681972 "SSB1 -- translation -- Heat shock HSP70 family, involved with the translational machinery" YGR085C RPL11B 52 12.5 152.3 0.9962 1 1 0.97041757 iYGR085C 0.978354675 0.757179297 0.428685779 "RPL11B -- protein synthesis -- Ribosomal protein L11 (yeast L16YL22rp39BE. coli L5rat L11), nearly identical to Rpl11Ap" YOL039W RPP2A 49.4 12 152.1 0.996 1 1 0.920095068 iYOL040C 0.986685069 0.600456235 0.673503591 "RPP2A -- protein synthesis -- Acidic ribosomal protein P2A (L44A2YP2alphaE. coli L12eIBhuman P2alpha), plays a role in the elongation step" YGL123W RPS2 50.1 12 148.6 0.9958 1 1 0.966318014 iYGL124C 0.991165154 0.948284118 0.246331237 RPS2 -- protein synthesis -- Ribosomal protein S2 (yeast S4YS5YP9rp12E. coli S5rat S2) YBL087C RPL23A 54.2 14 147 0.9956 1 1 0.980130282 iYBL087C 0.995291061 0.959957765 0.703114727 "RPL23A -- protein synthesis -- Ribosomal protein L23 (yeast L17aYL32E. coli L14rat L23), nearly identical to Rpl23Bp" YNL178W RPS3 52.7 14 144.4 0.9954 1 1 0.920457763 iYNL179C-0 iYNL179C-1 0.342874268 0.926242596 0.786307908 0.198493551 0.797370332 "RPS3 -- protein synthesis -- Ribosomal protein S3 (rp13YS3mammalian S3), has a possible KH domain" YJR123W RPS5 37.4 10 142.9 0.9952 1 1 0.962550344 iYJR122W 0.981281829 0.995530726 0.056799871 RPS5 -- protein synthesis -- Ribosomal small subunit RPS5 (rp14YS8S2mammalian S5) YHR203C RPS4B 45.9 12 140.7 0.995 1 1 0.959733784 iYHR203C 0.992944654 0.962083769 0.614663046 "RPS4B -- protein synthesis -- Ribosomal protein S4 (yeast S7YS6rp5rat and human S4), identical to Rps4Ap" YGL135W RPL1B 61.7 16 138.9 0.9948 1 1 0.976012195 iYGL136C 0.991967285 0.994972067 0.908959072 "RPL1B -- protein synthesis -- Large subunit ribosomal protein L1 (rat L10Aeubacterial L1archeal L1), identical to Rpl1Ap" YHR174W ENO2 61.1 17 134.7 0.9946 0.949418007 iYHR173C 0.846153169 0.932530004 0.591965096 ENO2 -- glycolysis -- Enolase 2 (2-phosphoglycerate dehydratase)converts 2-phospho-D-glycerate to phosphoenolpyruvate in glycolysis YER117W RPL23B 50.3 14 133.6 0.9944 1 1 0.959954454 iYER116C 0.988975343 0.977783263 0.286687631 "RPL23B -- protein synthesis -- Ribosomal protein L23 (yeast L17aYL32E. coli L14rat L23), nearly identical to Rpl23Ap" YDR154C YDR154C 61.4 17 130.7 0.9942 YDR154C -- unknown -- unknown function YDR050C TPI1 53.2 15 130.4 0.994 0.803376262 iYDR050C 0.858991757 0.41979116 0.807179987 "TPI1 -- glycolysis -- Triosephosphate isomerase, interconverts glyceraldehyde-3-phosphate and dihydroxyacetone phosphate" YOL121C RPS19A 45.6 13 128.2 0.9938 1 1 0.967391001 iYOL121C 0.992693026 0.962264151 0.438175351 "RPS19A -- protein synthesis -- Ribosomal protein S19 (rp55YS16Arat S19), nearly identical to Rps19Bp" YLR167W RPS31 52.5 15 126.6 0.9936 1 1 0.967557465 iYLR166C 0.98895835 0.930716695 0.74597164 RPS31 -- protein synthesis -- Fusion protein comprised of C-terminal half of ribosomal protein S31 and N-terminal half of ubiquitin (yeast S37YS24rat S27a) YGL103W RPL28 50.3 15 126.3 0.9934 1 1 0.981716523 iYGL104C IntYGL103W 0.992609447 0.95278586 0.857791754 0.337231969 0.733564572 RPL28 -- protein synthesis -- Ribosomal protein L28 (yeast L29YL24rp44mouse and rat L27a) YOL086C ADH1 51.1 15 125.6 0.9932 1 0.597234644 iYOL086C 0.965460828 0.384756584 0.399209486 "ADH1 -- glycolysis -- Alcohol dehydrogenase I, cytoplasmic isozyme reducing acetaldehyde to ethanol, regenerating NAD+" YJL190C RPS22A 39.1 12 124.1 0.993 1 1 0.975171513 iYJL190C 0.988807766 0.913986355 0.848167196 "RPS22A -- protein synthesis -- Ribosomal protein S22 (yeast S24rp50YS22rat S15A), nearly identical to Rps22Bp" YOR293W RPS10A 40.2 12 124 0.9926 1 1 0.961652867 iYOR292C 0.987197368 0.660159716 0.343378756 "RPS10A -- protein synthesis -- Ribosomal protein S10 (rat S10), nearly identical to Rps10Bp" YMR116C ASC1 43.9 13 124 0.9926 1 0.893521971 iYMR116C 0.948851403 0.871680643 0.900765243 "ASC1 -- protein synthesis (putative) -- Abundant effects on translational efficiency and cell size, has two WD (WD-40) repeats" YHR010W RPL27A 50.1 15 122.9 0.9922 1 1 0.961902721 iYHR009C IntYHR010W 0.985386052 0.925097389 0.852239768 0.235412299 0.250719987 "RPL27A -- protein synthesis -- Ribosomal protein L27 (yeast L27mammalian L27), identical to Rpl27Bp" YJL189W RPL39 46 14 122.9 0.9922 1 1 0.95258444 iYJL190C 0.988807766 0.576292666 0.848167196 RPL39 -- protein synthesis -- Ribosomal protein L39 YGR034W RPL26B 44.8 14 122.1 0.9919 1 1 0.961454784 iYGR033C 0.987378407 0.917956903 0.278131806 "RPL26B -- protein synthesis -- Ribosomal protein L26 (yeast L33YL33rat L26), nearly identical to Rpl26Ap" YJR094W-A RPL43B 41.4 13 122.1 0.9919 1 1 0.927396101 iYJR094C-0 iYJR094C-1 0.736135422 0.967842065 0.605945859 0.587077519 0.378826942 "RPL43B -- protein synthesis -- Ribosomal protein L43B (human L37A), identical to Rpl43Ap" YDR382W RPP2B 51.2 16 121.5 0.9917 1 0.952890758 iYDR381W 0.480458418 0.957025846 0.242656134 RPP2B -- protein synthesis -- Acidic ribosomal protein P2B (L45YPA1YL44CYP2 betaE. coli L12eIAhuman and rat P2) YNL302C RPS19B 42.9 13 121.4 0.9915 1 1 0.918665841 iYNL302C 0.972822332 0.840074122 0.076456504 "RPS19B -- protein synthesis -- Ribosomal protein S19 (rp55YS16Brat S19), nearly identical to Rps19Ap" YLR075W RPL10 55.5 17 120.6 0.9913 1 1 0.969570702 iYLR074C 0.965446025 0.973024741 0.430309378 RPL10 -- protein synthesis -- Ribosomal protein L10 (yeast L9) YDL130W RPP1B 40.8 12.5 120 0.9911 1 1 YDL130W-A iYDL130W-A 0.962267233 0.991910612 0.262724853 0.328560849 0.560103964 RPP1B -- protein synthesis -- Acidic ribosomal protein P1B (L44primeAxYP1betaE. coli L12eIIBhuman and rat P1beta) YOR182C RPS30B 51.2 16 119.4 0.9909 1 0.962279645 iYOR182C 0.820741405 0.428700732 0.42985365 "RPS30B -- protein synthesis -- Ribosomal protein S30B (mammalian S30), identical to Rps30Ap" YIL133C RPL16A 27.4 8 119.3 0.9907 1 1 0.945180429 iYIL133C 0.987965791 0.908368274 0.573911631 "RPL16A -- protein synthesis -- Ribosomal protein L16 (rp22), nearly identical to Rpl16Bp" YKL056C YKL056C 47.4 15 118.7 0.9905 0.852290009 iYKL056C 0.688827181 0.708495776 0.419023152 "YKL056C -- unknown -- Protein possibly involved in cytoplasmic ribosome function, has similarity to translationally controlled tumor protein (TCTP) of animal cells and higher plants" YPR132W RPS23B 42.2 13 118.1 0.9903 1 1 0.945197694 iYPR131C 0.978777689 0.561710372 0.063725095 "RPS23B -- protein synthesis -- Ribosomal protein S23 (yeast S28rp37YS14E. coli S12rat S23), identical to Rps23Ap" YLR287C-A RPS30A 54.2 17 116.6 0.9901 1 1 0.958377171 iYLR287C-A 0.992465259 0.556448993 0.323766627 "RPS30A -- protein synthesis -- Ribosomal protein S30A (mammalian S30), identical to Rps30Bp" YGL147C RPL9A 34.5 11 115.8 0.9899 1 0.945694295 iYGL147C 0.188112132 0.448884758 0.195836419 "RPL9A -- protein synthesis -- Ribosomal protein L9 (YL11rp25rp24E. coli L6rat L9), nearly identical to Rpl9Bp" YPL143W RPL33A 45.5 15 115.6 0.9897 1 1 0.948009226 iYPL144W IntYPL143W 0.96529996 0.934599878 0.875586275 0.362875972 "RPL33A -- protein synthesis -- Ribosomal protein L33 (yeast L37YL37rp47rat L35A), nearly identical to Rpl33Bp" YPL131W RPL5 37 12 115.4 0.9895 1 1 0.872377716 iYPL132W 0.96977249 0.262504224 0.637665968 "RPL5 -- protein synthesis -- Ribosomal protein L5 (yeast L1YL3rat L5), the sole 5S rRNA-associated ribosomal protein" YML026C RPS18B 29.3 9 114.8 0.9893 1 1 0.929464639 iYML026C 0.971598079 0.706864564 0.694247502 "RPS18B -- protein synthesis -- Ribosomal protein S18 (E. coli S13rat S18), identical to Rps18Ap" YBR031W RPL4A 44.6 15 113.2 0.9891 1 0.878142424 iYBR030W 0.377640571 0.956844398 0.186577398 "RPL4A -- protein synthesis -- Ribosomal protein L4 (yeast L2YL2rp2Xenopus L1Drosophila L1rat L4), nearly identical to Rpl4Bp" YDL191W RPL35A 41.2 14 113.1 0.9889 1 1 0.959142758 iYDL192W IntYDL191W 0.994037988 0.971908744 0.74663225 0.916612955 0.855607966 "RPL35A -- protein synthesis -- Ribosomal protein L35 (rat L35), identical to Rpl35Bp" YNL031C HHT2 37.6 12 111.7 0.9887 0.918971222 iYNL031C 0.486693347 0.944018714 0.575219811 "HHT2 -- chromatin structure -- Histone H3, identical to Hht1p" YML024W RPS17A 36.4 12 110.7 0.9885 1 1 0.945596734 iYML025C 0.991089628 0.90622506 0.056465274 "RPS17A -- protein synthesis -- Ribosomal protein S17 (rp51rat S17), nearly identical to Rps17Bp" YCR012W PGK1 60.4 20 110.5 0.9883 0.919472585 iYCR011C 0.746110646 0.901904263 0.217247335 PGK1 -- glycolysis -- Phosphoglycerate kinase YKL180W RPL17A 33.2 11 109.7 0.9881 1 1 0.947662388 iYKL181W 0.952801601 0.921588726 0.69668807 "RPL17A -- protein synthesis -- Ribosomal protein L17 (yeast L20YL17E. coli L22rat and human L17), nearly identical to Rpl17Bp" YDL083C RPS16B 31.2 11 109.5 0.9879 1 1 0.958887857 iYDL083C 0.998369768 0.329418723 0.683603734 "RPS16B -- protein synthesis -- Ribosomal protein S16 (rp61Rrat S16), identical to Rps16Ap" YBL092W RPL32 37 13 108.5 0.9877 1 1 0.888452823 iYBL093C 0.98206533 0.586013645 0.655546688 RPL32 -- protein synthesis -- Ribosomal protein L32 YOR234C RPL33B 36.5 12.5 107.8 0.9875 1 1 0.946819749 iYOR234C YOR235W 0.988788132 0.987736951 0.87150838 0.38624208 0.250625151 "RPL33B -- protein synthesis -- Ribosomal protein L33 (yeast L37YL37rp47rat L35A), nearly identical to Rpl33Ap" YPL220W RPL1A 44.8 16 106.9 0.9873 1 1 0.978306846 iYPL221W 0.982413434 0.946438655 0.377573823 "RPL1A -- protein synthesis -- Large subunit ribosomal protein L1 (rat L10Aeubacterial L1archeal L1), identical to Rpl1Bp" YPR080W TEF1 49.7 17 106.7 0.9871 1 0.952291632 iYPR079W 0.996651421 0.793103448 0.108430799 "TEF1 -- protein synthesis -- Translation elongation factor EF-1alpha, identical to Tef2p" YKL006W RPL14A 34.1 12 106.2 0.9869 1 1 0.964819242 iYKL006C-A 0.979317633 0.872953134 0.713733235 "RPL14A -- protein synthesis -- Ribosomal protein L14 (mammalian L14), nearly identical to Rpl14Bp" YDL075W RPL31A 45.4 16 104.4 0.9867 1 1 0.926033603 iYDL076C 0.973746268 0.614844374 0.106832098 "RPL31A -- protein synthesis -- Ribosomal protein L31 (yeast L34YL36YL28rat L31), nearly identical to Rpl31Bp" YHL015W RPS20 42.9 15 104.1 0.9863 1 1 0.962695484 iYHL016C 0.966818835 0.665880503 0.291179337 RPS20 -- protein synthesis -- Ribosomal protein S20 (E. coli S10Xenopus S22rat and human S20) YLR388W RPS29A 38.2 14 104.1 0.9863 1 1 0.75531304 iYLR387C 0.976171593 0.300501934 0.731923384 "RPS29A -- protein synthesis -- Ribosomal protein S29 (yeast S36YS29rat S29), similar to Rps29Bp" YBR010W HHT1 45.5 16 103.3 0.9861 0.914663789 iYBR009C 0.482182923 0.955566527 0.627374302 "HHT1 -- chromatin structure -- Histone H3, identical to Hht2p" YLR044C PDC1 43.7 16 103.2 0.9859 1 0.915259139 iYLR044C 0.978186951 0.733483725 0.641946191 PDC1 -- glycolysis -- Pyruvate decarboxylase isozyme 1 YLR061W RPL22A 39 14 102.1 0.9857 1 1 0.972267797 iYLR060W 0.960405458 0.613720852 0.548338374 "RPL22A -- protein synthesis -- Ribosomal protein L22, similar to Rpl22Bp" YAL038W CDC19 50.4 18 101.3 0.9855 1 0.938255472 iYAL039C-0 iYAL039C-1 0.845290926 0.947763209 0.744658157 0.825532274 0.179010375 "CDC19 -- glycolysis -- Pyruvate kinase, catalyzes final step in glycolysis" YOL109W ZEO1 39.4 15 98.9 0.9851 1 0.94145371 iYOL110W 0.9641438 0.776467505 0.019632881 ZEO1 -- zeocin resistance -- leads to resistance to zeocin when overproduced YJR009C TDH2 34.1 13 98.9 0.9851 1 0.93714383 iYJR009C-0 iYJR009C-1 0.440022378 0.374192569 0.8865048 0.541841521 0.866065627 "TDH2 -- glycolysis -- Glyceraldehyde-3-phosphate dehydrogenase 2, converts D-glyceraldehyde 3-phosphate to 1,3-dephosphoglycerate" YOR063W RPL3 36.7 14 97.4 0.9849 1 0.898423962 iYOR062C 0.452407721 0.918868837 0.740143839 "RPL3 -- protein synthesis -- Ribosomal protein L3 (YL1rp1rat L3) , responsible for trichodermin resistance and involved in maintenance of dsRNA viruses" YOL040C RPS15 30.6 12 97.2 0.9847 1 1 0.879805142 iYOL040C 0.986685069 0.435992579 0.673503591 RPS15 -- protein synthesis -- Ribosomal protein S15 (yeast S21rp52E. coli S19rat S15RIG protein) YNL162W RPL42A 32.1 12 96.2 0.9845 1 1 0.961354547 iYNL163C 0.976840993 0.891959394 0.86632083 "RPL42A -- protein synthesis -- Ribosomal protein L42 (yeast L41YL27YP44human and rat L36A), identical to Rpl42Bp" YDR450W RPS18A 33.7 13 95.4 0.9843 1 1 0.95885076 iYDR449C 0.983170496 0.818226121 0.542631282 "RPS18A -- protein synthesis -- Ribosomal protein S18 (E. coli S13rat S18), identical to Rps18Bp" YPR102C RPL11A 34.5 13 95 0.984 1 1 0.962893938 iYPR102C 0.993661589 0.738007076 0.262011173 "RPL11A -- protein synthesis -- Ribosomal protein L11 (yeast L16YL22rp39AE. coli L5rat L11), nearly identical to Rpl11Bp" YGL008C PMA1 43.1 17 95 0.984 0.914205976 iYGL008C 0.757011612 0.749888402 0.143545117 "PMA1 -- H+ homeostasis -- H+-transporting P-type ATPase of plasma membrane required for nutrient uptake and pH homeostasis, activity is rate limiting for growth at low pH" YOR369C RPS12 35.6 14 94.5 0.9838 1 1 0.792336913 iYOR369C 0.977510757 0.130364988 0.743089976 RPS12 -- protein synthesis -- Ribosomal protein S12 (rat S12) YIL052C RPL34B 34.4 14 93.8 0.9836 1 1 0.934649263 iYIL052C 0.975158775 0.959226771 0.415726716 "RPL34B -- protein synthesis -- Ribosomal protein L34 (rat L34), nearly identical to Rpl34Ap" YLR441C RPS1A 31 12.5 93.2 0.9834 1 1 iYLR441C 0.990521645 0.34002371 "RPS1A -- protein synthesis -- Ribosomal protein S1 (rp10rat S3A), nearly identical to Rps1Bp" YPR043W RPL43A 42.3 17 92.9 0.9832 1 1 0.95315301 iYPR042C 0.944816701 0.857293697 0.584206848 "RPL43A -- protein synthesis -- Ribosomal protein L43A (human L37A), identical to Rpl43Bp" YHL001W RPL14B 34.8 14 91.5 0.983 1 1 0.979612968 iYHL002W 0.983938009 0.968981631 0.266161213 "RPL14B -- protein synthesis -- Ribosomal protein L14 (mammalian L14), nearly identical to Rpl14Ap" YOL120C RPL18A 31.5 13 91.3 0.9828 1 1 0.985381504 iYOL120C 0.533483399 0.978381867 0.507297854 "RPL18A -- protein synthesis -- Ribosomal protein L18 (rp28rat L18), identical to Rpl18Bp" YGL030W RPL30 36.7 15 89.9 0.9826 1 1 0.971730122 iYGL031C 0.986535535 0.959060123 0.815923207 RPL30 -- protein synthesis -- Large-subunit ribosomal protein L30 (yeast L32YL38rp73mouse and rat L30) YBR118W TEF2 49.6 20 89.6 0.9824 1 0.96135838 iYBR117C 0.987106709 0.778387969 0.476502446 "TEF2 -- protein synthesis -- Translation elongation factor EF-1alpha, identical to Tef1p" YLR249W YEF3 26.4 11 87.7 0.9822 0.895497856 iYLR248W 0.903637948 0.856481481 0.229613385 "YEF3 -- protein synthesis -- Translation elongation factor EF-3A, member of non-transporter group of ATP-binding cassette (ABC) superfamily" YDR500C RPL37B 41.9 18 87.6 0.982 1 1 0.983298808 iYDR500C 0.989216992 0.835723493 0.149021663 "RPL37B -- protein synthesis -- Ribosomal protein L37 (yeast L46) (rat L37), nearly identical to Rpl37Bp" YBR181C RPS6B 33.8 14 87.2 0.9818 1 1 0.922309721 iYBR181C 0.992063689 0.839106145 0.532960894 "RPS6B -- protein synthesis -- Ribosomal protein S6 (yeast S10YS4rp9human, mouse, and rat S6), identical to Rps6Ap" YDR447C RPS17B 34.5 15 86.2 0.9816 1 1 0.968997895 iYDR447C 0.981874847 0.970396064 0.633419272 "RPS17B -- protein synthesis -- Ribosomal protein S17 (rp51rat S17), nearly identical to Rpl17Ap" YHR055C CUP1B 50.5 22 85.7 0.9814 0.267936511 iYHR055C 0.188794455 0.74612929 0.610055231 CUP1B -- Cu2+ ion homeostasis -- Metallothionein (copper chelatin)identical to Cup1Ap YLR185W RPL37A 32.1 14 85.2 0.9812 1 1 0.958919731 iYLR184W 0.965031569 0.912020625 0.721714803 "RPL37A -- protein synthesis -- Ribosomal protein L37 (yeast L46rat L37), nearly identical to Rpl37Bp" YIL053W RHR2 24.9 11 84.9 0.981 1 0.909242723 iYIL054W 0.886985467 0.687865497 0.303793302 RHR2 -- glycerol metabolism -- DL-glycerol phosphate phosphatase YDR461W MFA1 14.4 6 84.4 0.9808 0.692209748 iYDR460W 0.4326316 0.569026698 0.396363038 "MFA1 -- mating -- Mating pheromone a-factor, nearly identical to a-factor encoded by MFA2, exported from the cell by Ste6p" YOR096W RPS7A 26.7 11.5 83.8 0.9806 1 1 0.941135756 iYOR095C 0.976495063 0.755559136 0.509506929 "RPS7A -- protein synthesis -- Ribosomal protein S7 (rp30human S7Xenopus S8), nearly identical to Rps7Bp" YDR064W RPS13 28.2 12 83.7 0.9804 1 1 0.954455666 iYDR063W IntYDR064W 0.957834805 0.970552012 0.673779456 0.812769354 0.821881092 RPS13 -- protein synthesis -- Ribosomal protein S13 (yeast S27YS15rat S13) YDL136W RPL35B 32.1 14 82.6 0.98 1 1 0.961561597 iYDL137W 0.988039429 0.703616352 0.796727853 "RPL35B -- protein synthesis -- Ribosomal protein L35 (rat L35), identical to Rpl35Ap" YDL082W RPL13A 25.9 12 82.6 0.98 1 1 0.968217252 iYDL083C 0.998369768 0.927508373 0.683603734 "RPL13A -- protein synthesis -- Ribosomal protein L13 (rat L13), nearly identical to Rpl13Bp" YDR033W MRH1 23.6 11 82.3 0.9798 0.659137502 iYDR032C-0 iYDR032C-1 0.395648302 0.7248602 0.484047696 0.177075619 0.758853151 MRH1 -- unknown -- similarity to Yro2p YIL148W RPL40A 30.2 13.5 82.1 0.9796 1 1 0.961642831 iYIL149C 0.985554147 0.94868316 0.599821313 "RPL40A -- protein synthesis -- Fusion protein comprised of ribosomal protein L40 (C-terminal half) and ubiquitin (N-terminal half) (rat L40), identical to Rpl40Bp" YDL081C RPP1A 34.2 15 82 0.9794 1 0.783147904 iYDL081C 0.494050821 0.391263941 0.389399357 RPP1A -- protein synthesis -- Acidic ribosomal protein P1A (A1YP1alphaE. coli L12eIIAhuman and rat P1) YHR053C CUP1A 48.9 22 81.5 0.9792 0.200059486 iYHR053C 0.186288994 0.78026942 0.518437297 CUP1A -- Cu2+ ion homeostasis -- Metallothionein (copper chelatin)identical to Cup1Bp YJR145C RPS4A 25.5 12 81.2 0.979 1 1 0.963562929 iYJR145C 0.990511147 0.983954579 0.710817133 "RPS4A -- protein synthesis -- Ribosomal protein S4 (yeast S7YS6rp5rat and human S4), identical to Rps4Bp" YPL090C RPS6A 27.2 12 80.9 0.9788 1 1 0.738857503 iYPL090C 0.976084742 0.090828426 0.294988892 "RPS6A -- protein synthesis -- Ribosomal protein S6 (yeast S10YS4rp9human, mouse, and rat S6), identical to Rps6Bp" YLR406C RPL31B 24 11.3 80.1 0.9786 1 1 0.616325667 iYLR406C 0.996825698 0.449876983 0.935035914 "RPL31B -- protein synthesis -- Ribosomal protein L31 (yeast L34YL36YL28rat L31), nearly identical to Rpl31Ap" YDR471W RPL27B 22.1 10 79.9 0.9784 1 1 0.961179588 iYDR470C 0.990595751 0.931707357 0.435859459 "RPL27B -- protein synthesis -- Ribosomal protein L27 (yeast L27mammalian L27), identical to Rpl27Ap" YDR225W HTA1 29.1 13.5 79 0.9782 0.860142561 iYDR224C 0.879388188 0.828010952 0.712294554 "HTA1 -- chromatin structure -- Histone H2A, identical to Hta2p" YOL127W RPL25 28.4 13 78.5 0.978 1 1 0.970579941 iYOL128C 0.995341592 0.982818424 0.676952193 RPL25 -- protein synthesis -- Ribosomal protein L25 (YL25rp61LE. coli L23rat L23a) YOR167C RPS28A 32.8 15.5 77.6 0.9778 1 0.675310284 iYOR167C 0.663755581 0.506953016 0.375370679 "RPS28A -- protein synthesis -- Ribosomal protein S28 (yeast S33YS27mammalian S28), nearly identical to Rps28Bp" YLR448W RPL6B 25 12 77.4 0.9776 1 1 0.94931424 iYLR447C 0.989642005 0.894305509 0.705422529 "RPL6B -- protein synthesis -- Ribosomal protein L6 (yeast L17BYL16Bhuman L6), nearly identical to Rpl6Ap" YBR189W RPS9B 25.7 12 76.2 0.9774 1 1 0.979570835 iYBR188C 0.986112327 0.888844075 0.827827908 "RPS9B -- protein synthesis -- Ribosomal protein S9 (yeast S13YS11YP28rp21E. coli S4rat S9), nearly identical to Rps9Ap" YNL069C RPL16B 27.1 13 75.5 0.9772 1 1 0.942941632 iYNL069C 0.990468502 0.933128983 0.240681313 "RPL16B -- protein synthesis -- Ribosomal protein L16 (rp23), nearly identical to Rpl16Ap" YDR418W RPL12B 23.1 11 74.9 0.977 1 1 0.959245345 0.961655558 "RPL12B -- protein synthesis -- Ribosomal protein L12 (yeast L15YL23E. coli L11rat L12a), identical to Rpl12Ap" YDR134C YDR134C 37.6 19 74 0.9768 0.709140606 iYDR134C 0.661289494 0.372705507 0.238398324 "YDR134C -- unknown -- unknown function, probably pseudogene ORF, has strong similarity to FLO1" YOR312C RPL20B 25.8 13 73.7 0.9766 1 1 0.915724961 iYOR312C 0.955305225 0.646260183 0.446583951 "RPL20B -- protein synthesis -- Ribosomal protein L20, nearly identical to Rpl20Ap" YJL177W RPL17B 23.7 12 72 0.9764 1 1 0.93351642 iYJL178C 0.981795382 0.789202433 0.180526736 "RPL17B -- protein synthesis -- Ribosomal protein L17 (yeast L20YL17E. coli L22rat and human L17), nearly identical to Rpl17Ap" YGL253W HXK2 19.3 10 71.9 0.9761 0.858010052 iYGL254W 0.313906427 0.870695257 "HXK2 -- glycolysis -- Hexokinase II, converts hexoses to hexose phosphates in glycolysis and plays a regulatory role in glucose repression" YKL216W URA1 16.2 8 71.9 0.9761 0.23212202 iYKL217W 0.178964301 0.582846004 0.330164357 "URA1 -- pyrimidine biosynthesis -- Dihydroorotate dehydrogenase, catalyzes fourth step in pyrimidine biosynthesis pathway" YDR025W RPS11A 23.5 12.3 71.3 0.9759 1 1 0.917140123 0.736354776 "RPS11A -- protein synthesis -- Ribosomal protein S11 (yeast S18YS12rp41E. coli S17human and rat S11), identical to Rps11Bp" YKL156W RPS27A 26.6 14 71 0.9757 1 1 0.97383689 iYKL157W 0.98490652 0.889560263 0.444038337 "RPS27A -- protein synthesis -- Ribosomal protein S27 (yeast S27rp61YS20mammalian S27), nearly identical to Rps27Bp" YLR029C RPL15A 24.1 13 70.9 0.9755 1 0.914546422 iYLR029C 0.885812264 0.934690774 0.422169811 "RPL15A -- protein synthesis -- Ribosomal protein L15 (yeast L13YL10rp15Rrat L15), nearly identical to Rpl15Bp" YGL076C RPL7A 26.7 14 70.6 0.9753 1 1 0.934947666 iYGL076C 0.92733753 0.815055762 0.383365822 "RPL7A -- protein synthesis -- Ribosomal protein L7 (yeast L6YL8Arp11E. coli L30rat L7), nearly identical to Rpl7Bp" YBL003C HTA2 24.5 13 69.3 0.9751 0.790783736 iYBL003C 0.396439072 0.659853249 0.510546288 "HTA2 -- chromatin structure -- Histone H2A, identical to Hta1p" YKR094C RPL40B 21.7 11.5 69 0.9749 1 1 0.972994722 iYKR094C 0.988725428 0.937546285 0.5581189 "RPL40B -- protein synthesis -- Fusion protein comprised of ribosomal protein L40 (C-terminal half) and ubiquitin (N-terminal half), (rat L40), identical to Rpl40Ap" YCR031C RPS14A 33.5 18 68.6 0.9747 1 1 0.970642183 iYCR031C SNR189 0.391235882 0.982725285 0.981044724 0.415987739 0.583870448 "RPS14A -- protein synthesis -- Ribosomal protein S14A (rp59, E. coli S11, rat and human S14) involved in crytopleurine resistance, nearly identical to Rps14Bp" YHR141C RPL42B 24.4 13 67.2 0.9743 1 0.975469868 iYHR141C 0.601883986 0.976946517 0.063426911 "RPL42B -- protein synthesis -- Ribosomal protein L42 (yeast L41YL27YP44human and rat L36A), involved in replication of M1 and M2 double-stranded RNA (dsRNA) viruses, identical to Rpl42Ap" YLR300W EXG1 23.9 13 67.2 0.9743 0.785930703 iYLR299W 0.807684101 0.757142857 0.67661531 "EXG1 -- cell wall biogenesis -- Exo-beta-1,3-glucanase (I/II)major isoform involved in cell wall beta-glucan assembly" YLL045C RPL8B 23.5 13 66 0.9741 1 1 0.95757855 0.870816458 "RPL8B -- protein synthesis -- Ribosomal protein L8 (yeast L4rp6YL5human, rat, and mouse L7a), involved in maintenance of M1 dsRNA virusnearly identical to Rpl8Ap" YNL030W HHF2 23.9 14 65.3 0.9739 0.799575302 iYNL031C 0.486693347 0.708181048 0.575219811 "HHF2 -- chromatin structure -- Histone H4, identical to Hhf1p" YDR155C CPH1 30.6 17 65.1 0.9737 iYDR155C 0.292725389 0.497271513 "CPH1 -- protein folding -- Cyclophilin (peptidylprolyl cis-trans isomerase or PPIase) of cytosol, plays a role in the stress response" YER074W RPS24A 24.5 14 64.7 0.9735 1 1 0.95473387 iYER073W 0.985322246 0.68764914 0.352095517 "RPS24A -- protein synthesis -- Ribosomal protein S24 (rat S24), identical to Rps24Bp" YBR084C-A RPL19A 25.1 14 64.4 0.9733 1 1 0.940214165 iYBR084C-A 0.985655862 0.945712672 0.377094972 "RPL19A -- protein synthesis -- Ribosomal protein L19 (yeast L23YL14rp15Lrp33rat L19), nearly identical to Rpl19Bp" YKL152C GPM1 32.3 19 64 0.9731 1 0.928203959 iYKL152C 0.884347502 0.67382949 0.281359189 GPM1 -- glycolysis -- Phosphoglycerate mutase that converts 2-phosphoglycerate to 3-phosphoglycerate in glycolysis YLR333C RPS25B 20.9 12 63.9 0.9727 1 1 0.957323156 iYLR333C 0.991096001 0.949423248 0.740654206 "RPS25B -- protein synthesis -- Ribosomal protein S25B (yeast S31YS23rp45rat S25), identical to Rps25Ap" YEL027W CUP5 27.6 16 63.9 0.9727 0.343923804 iYEL028W YELCdelta3 0.667082291 0.684222885 0.467692556 0.907508862 0.514421528 CUP5 -- ATP synthesis -- Vacuolar H(+)-ATPase (V-ATPase) dicyclohexylcarbodiimide (DCCD)-binding 16 kDa proteolipid subunit (subunit c) of membrane (V0) sector YDR224C HTB1 21.2 12 63.7 0.9725 0.822197002 iYDR224C 0.879388188 0.417016375 0.712294554 HTB1 -- chromatin structure -- Histone H2B YDR385W EFT2 23.1 13 63.6 0.9723 0.820114197 iYDR384C 0.257096797 0.988207547 0.341614907 "EFT2 -- protein synthesis -- Translation elongation factor EF-2, identical to Eft1p, contains diphthamide which is not essential for its activity" YIL069C RPS24B 23.1 14 63.4 0.9721 1 1 0.91925684 iYIL069C 0.85623476 0.789434707 0.502355426 "RPS24B -- protein synthesis -- Ribosomal protein S24 (rat S24), identical to Rps24Ap" YML028W TSA1 24.9 15 62.7 0.9717 0.918401801 iYML029W 0.55127893 0.961902411 0.267403404 "TSA1 -- oxidative stress response -- Thioredoxin peroxidase, abundant thiol-specific antioxidant prevents formation of sulfur-containing radicals" YOR133W EFT1 23.9 14 62.7 0.9717 0.763899306 iYOR132W 0.560348542 0.704376479 0.713963056 "EFT1 -- protein synthesis -- Translation elongation factor EF-2, contains diphthamide which is not essential for activity, identical to Eft2p" YDR012W RPL4B 24.7 14.8 61.8 0.9715 1 0.706259641 iYDR011W 0.468295851 0.682119649 0.699898614 "RPL4B -- protein synthesis -- Ribosomal protein L4 (yeast L2YL2rp2Xenopus L1Drosophila L1rat L4), nearly identical to Rpl4Ap" YLR264W RPS28B 24 14 61.5 0.9711 1 0.821981686 iYLR263W 0.833141772 0.551799441 0.533979734 "RPS28B -- protein synthesis -- Ribosomal protein S28 (yeast S33YS27mammalian S28), nearly identical to Rps28Ap" YNL112W DBP2 11.5 7 61.5 0.9711 0.371726662 iYNL113W IntYNL112W 0.44593013 0.631942564 0.545198195 0.453878407 0.55805151 DBP2 -- mRNA decay -- ATP-dependent RNA helicase of DEAD box family YNL301C RPL18B 21.2 13 60.7 0.9709 1 1 0.980993088 iYNL301C 0.798203651 0.733524839 0.400388645 "RPL18B -- protein synthesis -- Ribosomal protein L18 (rp28rat L18), identical to Rpl18Ap" YBL027W RPL19B 23.6 14.5 60.5 0.9707 1 1 0.93891878 iYBL028C 0.982135054 0.942901235 0.831935709 "RPL19B -- protein synthesis -- Ribosomal protein L19 (yeast L23YL14rp15Lrp33rat L19), nearly identical to Rpl19Ap" YDL192W ARF1 28.5 18 59.9 0.9705 0.961435414 iYDL193W 0.896468819 0.813190383 0.809347644 "ARF1 -- secretion -- GTP-binding assembly of coated vesicles of secretory system, member of arf family" YMR142C RPL13B 19.4 12 59.7 0.9703 1 1 0.930470345 iYMR142C 0.989894369 0.697812887 0.44408788 "RPL13B -- protein synthesis -- Ribosomal protein L13 (rat L13), nearly identical to Rpl13Ap" YDR276C SNA1 21.6 13 59.6 0.9701 1 0.954511326 iYDR276C 0.967036926 0.540926685 0.829424833 "SNA1 -- unknown -- Small, abundant plasma membrane proteolipid protein, has similarity to stress-induced proteins" YEL009C GCN4 22.3 14 59.4 0.9697 1 0.927144114 iYEL009C 0.935478602 0.903727475 0.203351955 "GCN4 -- amino acid, purine biosynthesis -- Transcription factor of basic leucine zipper (bZIP) family, regulates general control in response to amino acid or purine starvation" YHR193C EGD2 26.7 17 59.4 0.9697 0.798867141 iYHR193C 0.895875186 0.58810854 0.217049679 EGD2 -- protein synthesis (putative) -- Alpha subunit of nascent polypeptide-associated complex YER056C-A RPL34A 17.2 11 59 0.9695 1 1 0.906302814 iYER056C-A 0.976564844 0.61887462 0.651478233 "RPL34A -- protein synthesis -- Ribosomal protein L34 (rat L34), nearly identical to Rpl34Bp" YGR060W ERG25 20.5 13 58.8 0.9691 0.585167903 iYGR059W SNR48 0.791032443 0.595914938 0.602484983 0.732242618 0.623831776 ERG25 -- sterol metabolism -- C-4 sterol methyl oxidaseenzyme of ergosterol biosynthesis pathway YJL158C CIS3 20.4 13 58.8 0.9691 0.590435243 iYJL158C 0.186333634 0.369949807 0.202387674 CIS3 -- unknown -- Cell wall similarity to members of Pir1p/Hsp150p/Pir3p family YDL061C RPS29B 23.4 15 58.2 0.9689 1 1 0.798890848 iYDL061C 0.989542094 0.273686755 0.337988827 "RPS29B -- protein synthesis -- Ribosomal protein S29 (yeast S36YS29rat S29), similar to Rps29Ap" YLR048W RPS0B 16.6 11 57.8 0.9687 1 1 0.948936072 iYLR047C 0.984267245 0.749526866 0.287681649 "RPS0B -- protein synthesis -- Ribosomal protein S0 (E. coli S2rat Sb), nearly identical to Rps0Ap" YKR059W TIF1 21.4 14 57.7 0.9685 0.879143402 iYKR058W 0.372263966 0.990090968 0.472937001 "TIF1 -- protein synthesis -- Translation initiation factor 4A (eIF4A) of DEAD box family, identical to Tif2p" YLR340W RPP0 24.6 16 57.6 0.9683 1 1 0.924066305 0.905219005 RPP0 -- protein synthesis -- Acidic ribosomal protein A0 YEL054C RPL12A 18.6 12 57.4 0.9682 1 1 0.952039471 iYEL054C 0.997878693 0.769005848 0.820175439 "RPL12A -- protein synthesis -- Ribosomal protein L12 (yeast L15YL23E. coli L11rat L12b), identical to Rpl12Bp" YLR325C RPL38 30.1 20 56.9 0.968 1 1 0.946285303 iYLR325C 0.087127668 0.808235867 0.066387029 RPL38 -- protein synthesis -- Ribosomal protein L38 YGR234W YHB1 8.8 6 56.3 0.9678 0.924452793 iYGR233C-0 iYGR233C-1 0.815014959 0.576538491 0.972794863 0.645357663 0.824723847 "YHB1 -- oxidative stress response (putative) -- Flavohemoglobin involved in protection from nitrosative stress, distantly related to animal hemoglobins" YDL055C PSA1 15.2 10 55.8 0.9676 1 0.86615605 iYDL055C-0 iYDL055C-1 0.953937151 0.970178413 0.936073424 0.201581028 0.564222826 PSA1 -- mannose metabolism -- Mannose-1-phosphate guanyltransferaseGDP-mannose pyrophosphorylase YEL017C-A 21.8 14.5 55.6 0.9674 0.529592957 iYEL017C-A 0.083591889 0.157844165 0.038833387 YGR214W RPS0A 17.1 11.5 55.3 0.9672 1 1 0.940348903 iYGR213C 0.96418684 0.976283301 0.395019385 "RPS0A -- protein synthesis -- Ribosomal protein S0 (E. coli S2rat Sa), nearly identical to Rps0Bp" YGR037C ACB1 15.4 10 54.7 0.967 0.212087398 iYGR037C 0.446577305 0.341021548 0.620020964 ACB1 -- fatty acid metabolism -- Acyl-coenzyme-A binding protein YPL037C EGD1 22 15 54.4 0.9668 0.709891533 iYPL037C 0.35176004 0.816588497 0.357722203 EGD1 -- transcription -- Beta subunit of nascent polypeptide-associated complex YML073C RPL6A 19.3 13 53.9 0.9666 1 1 0.961860932 iYML073C 0.981969312 0.880196584 0.673496256 "RPL6A -- protein synthesis -- Ribosomal protein L6 (yeast L17AYL16Ahuman L6), nearly identical to Rpl6Bp" YHR089C GAR1 14.4 10 53.8 0.9664 0.41590105 iYHR089C 0.621904136 0.195405311 0.598183089 GAR1 -- rRNA processing -- 35S rRNA processing and pseudouridinylationassociated with the H/ACA class small nucleolar RNAs YLL024C SSA2 20.1 14 53.4 0.9662 0.862240967 iYLL024C 0.610132337 0.803500847 0.535250162 SSA2 -- ER and mitochondrial translocation -- Cytoplasmic chaperonemember of HSP70 family YAL003W EFB1 19.1 14 52.3 0.966 0.812971521 iYAL004W 0.496737589 0.590638092 0.285497006 "EFB1 -- protein synthesis -- Translation elongation factor EF-1beta, GDP/GTP exchange factor for Tef1p/Tef2p" YMR143W RPS16A 15.8 11 52.2 0.9656 1 1 0.946407997 iYMR142C 0.989894369 0.373663208 0.44408788 "RPS16A -- protein synthesis -- Ribosomal protein S16 (rp61Rrat S16), identical to Rps16Bp" YMR251W-A HOR7 29.1 21 52.2 0.9656 0.634231444 iYMR251W 0.269827732 0.529087468 0.18612707 HOR7 -- unknown -- responsiveness to hyperosmolarity YNL096C RPS7B 14.4 10.5 51.4 0.9654 1 1 0.979211647 iYNL096C 0.941876357 0.973504484 0.092571705 "RPS7B -- protein synthesis -- Ribosomal protein S7 (rp30human S7Xenopus S8), nearly identical to Rps7Ap" YDL014W NOP1 15.2 11 51.1 0.9652 0.607520657 iYDL015C 0.800695409 0.418991196 0.311204324 "NOP1 -- rRNA processing, 35S -- Fibrillarin, protein associated with small nucleolar RNA (snoRNA) and required for 35S rRNA processing and methylation" YEL034W HYP2 25 18 50.9 0.965 1 0.96668205 iYEL035C 0.954231369 0.853996935 0.347897638 HYP2 -- protein synthesis -- Translation initiation factor eIF5Acontains essential hypusine modification YBR106W PHO88 19.8 15 50.3 0.9648 0.845240308 iYBR105C 0.647673062 0.925059856 0.453616087 PHO88 -- phosphate transport -- Membrane inorganic phosphate transport YMR230W RPS10B 17.5 13 50.1 0.9646 1 1 0.95617695 iYMR229C 0.98122463 0.658415005 0.658949746 "RPS10B -- protein synthesis -- Ribosomal protein S10 (rat S10), nearly identical to Rps10Ap" YHL033C RPL8A 20 15 49.6 0.9644 1 1 0.964788166 iYHL033C 0.942584623 0.939465409 0.345712623 "RPL8A -- protein synthesis -- Ribosomal protein L8 (yeast L4rp6YL5human, mouse, and rat L7a), involved in maintenance of M1 dsRNA virusnearly identical to Rpl8Bp" YMR242C RPL20A 15.4 12 49 0.9642 1 1 0.928128292 iYMR242C 0.958369823 0.837488686 0.750080567 "RPL20A -- protein synthesis -- Ribosomal protein L20, nearly identical to Rpl20Bp" YLR355C ILV5 14.3 11 48.5 0.964 0.883713065 iYLR355C 0.52481834 0.814874566 0.828230744 "ILV5 -- isoleucine and valine biosynthesis -- Ketol-acid reductoisomerase (acetohydroxy-acid reductoisomerase, alpha-keto-beta-hydroxylacil reductoisomerase), second step in valine and isoleucine biosynthesis pathway" YGR254W ENO1 17.1 13 48.1 0.9638 1 0.94145486 iYGR253C-0 iYGR253C-1 0.731051944 0.860937648 0.831292298 0.482618583 0.286793372 "ENO1 -- glycolysis -- Enolase 1 (2-phosphoglycerate dehydratase), converts 2-phospho-D-glycerate to phosphoenolpyruvate in glycolysis" YLR150W STM1 19.1 15 47.5 0.9636 0.577073524 iYLR149C 0.239450312 0.298073697 0.088247157 STM1 -- unknown -- specific affinity for guanine-rich quadruplex nucleic acidsmulticopy suppressor of pop2 and tom1 YLR058C SHM2 14.9 12 46 0.9634 0.492842622 iYLR058C 0.370348077 0.438688366 0.189950978 "SHM2 -- one-carbon interconversion -- Serine hydroxymethyltransferase (glycine hydroxymethyltransferase), cytosolic isoform, interconverts serine and glycine" YFL039C ACT1 21.1 17 45.5 0.963 0.859554627 iYFL039C 0.222191069 0.917660329 0.119383722 "ACT1 -- cytoskeleton -- Actin, involved in cell polarization, endocytosis, and other cytoskeletal functions" YJL138C TIF2 17 14 45.5 0.963 0.900302128 iYJL138C 0.133013606 0.945793337 0.054206663 "TIF2 -- protein synthesis -- Translation initiation factor 4A (eIF4A) of DEAD box family, identical to Tif1p" YHR183W GND1 15.5 13 45 0.9626 0.582243758 iYHR182W 0.068479845 0.85490822 0.118318008 "GND1 -- pentose phosphate cycle -- 6-Phosphogluconate dehydrogenase, decarboxylating, converts 6-phosphogluconate + NADP to ribulose-5-phosphate + NADPH + CO2" YER056C FCY2 14.9 12 45 0.9626 0.773786859 iYER056C 0.511137921 0.658138402 0.331108483 "FCY2 -- transport -- Cytosine/purine permease, member of purine/cytosine permease family of membrane transporters" YDR226W ADK1 16.1 13 44.4 0.9624 0.769277894 iYDR225W 0.680589283 0.942260657 0.189186603 ADK1 -- metabolism -- Adenylate kinase (GTP YEL040W UTR2 14.1 12 44.1 0.9622 0.660221451 iYEL041W 0.666938909 0.358325477 0.666913519 UTR2 -- unknown -- Cell wall protein YHR026W PPA1 22.3 19 43.9 0.9618 0.687368895 iYHR025W 0.449077469 0.771908171 0.386999909 PPA1 -- vacuolar acidification -- Proteolipid of vacuolar H(+)-ATPase (V-ATPase) YIL051C MMD1 15.9 13 43.9 0.9618 0.983338842 iYIL051C 0.674384276 0.831088166 0.49886443 MMD1 -- maintenance of mitochondrial DNA -- important for maintenance of mitochondrial DNA YGR159C NSR1 12.2 10 43.4 0.9616 1 0.613182408 0.196169194 "NSR1 -- nuclear protein targeting -- Nucleolar processing 20S to 18S rRNA, has 2 RNA recognition (RRM) domains and is member of GAR (glycine/arginine-rich repeats) family of proteins" YDL208W NHP2 13.4 11 43.1 0.9614 iYDL209C 0.390009145 0.312091635 NHP2 -- unknown -- Nucleolar protein required in association with H/ACA snoRNAs for ribosomal RNA pseudouridinylation YLR109W AHP1 26.4 23 42.8 0.9612 0.891356566 iYLR108C 0.447390395 0.764724661 0.492924528 AHP1 -- oxidative stress response -- Alkyl hydroperoxide reductase YFL026W STE2 6.7 6 42.7 0.961 0.707844704 iYFL027C 0.458348397 0.845230422 0.563482268 "STE2 -- mating -- Pheromone alpha-factor G protein-coupled receptor (GPCR), member of GPCR or seven transmembrane segments (7-TMS) superfamily" YGR209C TRX2 20.7 18 42.6 0.9608 0.66945189 iYGR209C 0.556389515 0.689203354 0.457621656 TRX2 -- DNA replication -- Thioredoxin II YLR056W ERG3 14 12 42.5 0.9606 0.859353019 iYLR055C 0.145100604 0.743494424 0.070314215 "ERG3 -- sterol metabolism -- C-5 sterol desaturaseiron, non-heme, oxygen-requiring enzyme of ergosterol biosynthesis pathway" YNL067W RPL9B 14.6 13 42.1 0.9604 1 1 0.948598733 iYNL068C 0.972523751 0.556817247 0.284591195 "RPL9B -- protein synthesis -- Ribosomal protein L9 (YL11rp25rp24E. coli L6rat L9), nearly identical to Rpl9Ap" YEL026W SNU13 17.2 15 41.9 0.9603 0.643223415 iYEL027W 0.710164741 0.581269662 0.740114904 "SNU13 -- mRNA splicing (putative) -- Component of U4/U6.U5 snRNP, has similarity to nucleolar snoRNP protein Nhp2p" YNL209W SSB2 14.8 13 41 0.9599 0.763822359 iYNL210W 0.507059677 0.844308454 0.468419779 "SSB2 -- translation -- Heat shock HSP70 family, cytoplasmic" YHR094C HXT1 11.2 10 41 0.9599 0.416531853 iYHR094C 0.628592348 0.531391426 0.501995211 "HXT1 -- transport -- Low-affinity hexose transporter, member of hexose transporter family of major facilitator superfamily (MFS), induced by glucose only at high concentration" YER055C HIS1 11.7 11 40.8 0.9597 0.83094704 iYER055C 0.828034241 0.909010244 0.908364927 "HIS1 -- histidine biosynthesis -- ATP phosphoribosyltransferase, first step in histidine biosynthesis pathway" YDR233C YDR233C 12 11 40.4 0.9595 0.836429629 iYDR233C 0.311246803 0.93612707 0.407356619 YDR233C -- unknown -- unknown function YNL327W EGT2 10.4 10 40.3 0.9593 0.677201466 iYNL328C 0.899702578 0.10728402 0.284217641 "EGT2 -- cell cycle -- Cell-cycle regulation protein, may be involved in the correct timing of cell separation after cytokinesis" YOL139C CDC33 15.6 14 40.1 0.9591 0.57856163 iYOL139C 0.458252112 "CDC33 -- protein synthesis -- Translation initiation factor eIF4E, mRNA cap-binding protein found in association with Caf20p" YDR353W TRR1 14.7 14 39.8 0.9589 0.138377754 iYDR352W 0.642644035 0.356156595 0.539727353 "TRR1 -- pyrimidine metabolism -- Thioredoxin reductase, component of yeast peroxidase" YIL078W THS1 16.6 16 39.3 0.9587 0.639666506 iYIL079C 0.26756644 0.898565904 0.51908707 "THS1 -- protein synthesis -- Threonyl-tRNA synthetase, cytoplasmic, member of class II family of aminoacyl-tRNA synthetases" YJR104C SOD1 14.7 14 38.8 0.9585 0.711805625 iYJR104C 0.416519472 0.858059738 0.850073225 SOD1 -- oxidative stress response -- Copper-zinc superoxide dismutase YCR024C-A PMP1 21.3 20 38.7 0.9583 1 0.723775786 iYCR024C-A 0.977070121 0.184481198 0.373104549 PMP1 -- H+ homeostasis -- Plasma membrane proteolipid associated with Pma1p YBR048W RPS11B 15 16 38.3 0.9579 1 1 0.934386362 iYBR047W IntYBR048W 0.996583628 0.919823061 0.703637977 0.601608187 0.55490822 "RPS11B -- protein synthesis -- Ribosomal protein S11 (yeast S18YS12rp41E. coli S17human and rat S11), identical to Rps11Bp" YPR035W GLN1 14.6 14 38.3 0.9579 0.874696058 iYPR034W 0.522099892 0.702095302 0.466020266 "GLN1 -- glutamine biosynthesis -- Glutamine synthetase, combines ammonia to glutamate in ATP-driven reaction" YDR399W HPT1 10.4 10 38.2 0.9577 0.910298287 iYDR398W 0.166504776 0.957973703 0.160119384 HPT1 -- purine biosynthesis -- Hypoxanthine-guanine phosphoribosyl transferase YBR009C HHF1 17.3 17 38 0.9575 0.82300885 iYBR009C 0.482182923 0.725299282 0.627374302 "HHF1 -- chromatin structure -- Histone H4, identical to Hhf2p" YLR372W SUR4 12.6 12 37.9 0.9573 0.549276374 iYLR371W 0.557985899 0.658898643 0.534317638 SUR4 -- fatty acid metabolism -- the conversion of 24-carbon fatty acids to 26-carbon fatty acids YMR194W RPL36A 14 14 37.6 0.9571 1 1 0.945988462 0.715234102 "RPL36A -- protein synthesis -- Ribosomal protein L36 (yeast L39YL39rat L36), nearly identical to Rpl36Bp" YDR345C HXT3 12.9 13 37.5 0.9569 0.576091326 iYDR345C-0 iYDR345C-1 0.401627794 0.816714107 0.38791423 0.871588188 0.508197857 "HXT3 -- transport -- Low-affinity hexose transporter, member of hexose transporter family of major facilitator superfamily (MFS)" YML063W RPS1B 11.2 11 37.2 0.9567 1 1 0.969580457 iYML064C 0.985399771 0.883822108 0.525299282 "RPS1B -- protein synthesis -- Ribosomal protein S1 (rp10rat S3A), nearly identical to Rps1Ap" YNL244C SUI1 12.5 13 36.7 0.9565 0.335664787 iYNL244C 0.352373365 0.335000403 0.205878822 SUI1 -- protein synthesis -- 16 kDa subunit of translation initiation factor eIF3involved in initiation and in monitoring translational accuracy during elongation YER131W RPS26B 8.4 8 36.6 0.9561 1 1 0.91030159 iYER130C 0.974083212 0.830486626 0.494533635 "RPS26B -- protein synthesis -- Ribosomal protein S26 (rat S26), nearly identical to Rps26Ap" YHR162W YHR162W 13.7 14 36.6 0.9561 0.685909492 iYHR161C 0.018329448 0.974248913 0.112893936 YHR162W -- unknown -- unknown function YER177W BMH1 16.5 17 35.3 0.9559 0.835895134 iYER176W 0.087477464 0.778301887 0.042458101 "BMH1 -- unknown -- signal transduction during filamentous growth, homolog of mammalian 14-3-3 protein" YPR074C TKL1 11.2 12 35.2 0.9557 0.870203775 iYPR074C 0.67401559 0.953232243 0.5195425 TKL1 -- pentose phosphate cycle -- Transketolase 1 YPL198W RPL7B 14.3 16.5 34.3 0.9555 1 1 0.849048121 iYPL199C SNR59 0.943936035 0.815888078 0.621924659 0.325401307 0.451556265 "RPL7B -- protein synthesis -- Ribosomal protein L7 (yeast L6YL8Brp11E. coli L30rat L7), nearly identical to Rpl7Ap" YOR045W TOM6 12.1 13 34.2 0.9553 0.925692084 iYOR044W 0.684971067 0.583333333 TOM6 -- mitochondrial protein targeting -- Mitochondrial integral outer membrane protein associated with protein translocation complex YHR007C ERG11 14.7 16 34 0.9549 0.765880141 iYHR007C 0.339797873 0.352884306 0.185851416 "ERG11 -- sterol metabolism -- Cytochrome P450 (lanosterol 14alpha-demethylase), essential for biosynthesis of ergosterol" YPR145W ASN1 12 13 34 0.9549 0.546611456 iYPR144C SNR45 0.585774404 0.811626906 0.465059399 0.51931919 0.455607669 ASN1 -- asparagine biosynthesis -- Asparagine synthetase (L-aspartate YDR002W YRB1 17.1 19 33.6 0.9545 0.310614753 iYDR001C 0.158206343 0.436286678 0.208704147 YRB1 -- nuclear protein targeting -- stimulates GTPase activity of Gsp1p and Gsp2p in the presence of Rna1p YGL055W OLE1 11.2 12 33.6 0.9545 0.726751401 iYGL056C 0.166284433 0.975067884 0.408395102 "OLE1 -- fatty acid metabolism -- Stearoyl-CoA desaturase(delta-9 fatty acid desaturase), required for synthesis of unsaturated fatty acids" YDR133C YDR133C 26.5 29 33.5 0.9543 0.830120545 0.283219623 YDR133C -- unknown -- unknown function YMR321C YMR321C 8.8 10 33 0.9541 0.872792174 iYMR321C 0.561233731 0.878877643 0.203678309 "YMR321C -- unknown -- Protein nearly identical to a fragment of Sam4p, possibly a pseudogene" YOR310C NOP5 12.2 14 32.7 0.9539 0.417829095 iYOR310C 0.422821407 0.521599605 0.456365091 NOP5 -- ribosome biogenesis -- Nucleolar protein component of box C/D snoRNPs involved in 2'-O-methylation of ribosomal RNAs YHR179W OYE2 13.6 16 31.9 0.9535 0.734879115 iYHR178W 0.668526254 0.882202713 0.784597072 "OYE2 -- unknown -- NADPH dehydrogenase (old yellow enzyme), isoform 2" YLR175W CBF5 11.2 13 31.9 0.9535 0.554193391 iYLR174W 0.790758642 0.527129022 0.6753927 "CBF5 -- mitosis -- Putative ribosomal RNA pseudouridine synthase, associated with H/ACA class small nucleolar RNAs" YNL055C POR1 13.8 16 31.7 0.9533 0.564934238 iYNL055C 0.287177472 0.81475739 0.167701863 POR1 -- transport -- Outer mitochondrial membrane porin (voltage-dependent anion-selective channel) YLR344W RPL26A 9.4 11 31.2 0.9531 1 1 0.971827448 iYLR343W iYLRCdelta21 0.555447343 0.934336642 0.907347728 0.433235867 0.737513371 "RPL26A -- protein synthesis -- Ribosomal protein L26 (yeast L33YL33rat L26), nearly identical to Rpl26Bp" YGR279C SCW4 14 17 30.9 0.9527 0.395638591 iYGR279C 0.172432106 0.314511575 0.349358716 "SCW4 -- cell wall biogenesis -- Cell wall protein, has similarity to Scw10, Bgl2p, and other cell wall glucanases" YML106W URA5 12.7 15 30.9 0.9527 0.330446614 iYML107C 0.692326372 0.861182726 0.418649673 "URA5 -- pyrimidine biosynthesis -- Orotate phosphoribosyltransferase 1, catalyzes the fifth step in the pyrimidine biosynthesis pathway" YKL164C PIR1 14.6 17 30.8 0.9525 0.57601664 iYKL164C-0 iYKL164C-1 0.276315288 0.282097354 0.402130189 0.355140187 0.379728651 "PIR1 -- unknown -- tolerance to heat shock, member of Pir1p/Hsp150p/Pir3p family" YGR027C RPS25A 14.4 17 30.7 0.952 1 1 0.96840582 iYGR027C YGRCdelta12 0.986048156 0.808963222 0.957983927 0.709417398 0.532872542 "RPS25A -- protein synthesis -- Ribosomal protein S25A (yeast S31YS23rp45rat S25), identical to Rps25Bp" YBR196C PGI1 15.4 18 30.7 0.952 0.945489988 iYBR196C 0.90277436 0.974701901 0.332903122 "PGI1 -- glycolysis -- Glucose-6-phosphate isomerase, converts glucose 6-phosphate to fructose 6-phosphate" YBL030C PET9 14.3 17 30.7 0.952 0.614959714 iYBL030C-0 iYBL030C-1 0.772236947 0.946168319 0.748901506 0.648069961 0.513618037 PET9 -- transport -- ADP/ATP carrier mitochondrial carrier (MCF) family YOR153W PDR5 12 14 30.6 0.9518 0.842604276 iYOR152C-0 iYOR152C-1 0.13747787 0.033714808 0.813886672 0.226815642 0.060834958 "PDR5 -- drug resistance -- Drug-efflux pump involved in resistance to multiple drugs, member of ATP-binding cassette (ABC) superfamily" YLR043C TRX1 14.4 18 30.4 0.9516 0.862033552 iYLR043C 0.722220869 0.891975309 0.294311956 TRX1 -- DNA replication -- Thioredoxin I YGR285C ZUO1 17 21 30.1 0.9512 0.53625071 iYGR285C 0.387558416 0.628092578 0.202007735 "ZUO1 -- unknown -- Zuotin (Z-DNA-binding protein), has region of similarity to E. coli DnaJ chaperonin" YPR062W FCY1 12.9 16 30.1 0.9512 0.304549829 iYPR061C 0.238698946 0.442689048 0.458014036 FCY1 -- pyrimidine metabolism -- Cytosine deaminase YDR433W YDR433W 11.9 15 29.9 0.951 0.206098191 0.123900944 YDR433W -- unknown -- unknown functionquestionable ORF YMR202W ERG2 12.3 15 29.8 0.9508 0.682852319 iYMR201C 0.234393932 0.916431395 0.334468903 ERG2 -- sterol metabolism -- Sterol C8-C7 isomerase (C-8 sterol isomerase)enzyme of ergosterol biosynthesis pathway YGR155W CYS4 9.4 12 29.5 0.9506 0.793808133 iYGR154C 0.121372576 0.835674381 0.209001893 CYS4 -- methionine biosynthesis -- Cystathionine beta-synthase (beta-CTSase)converts serine and homocysteine to cystathionine YER043C SAH1 11.3 14 29.4 0.9504 0.790904561 iYER043C 0.336301206 0.937000887 0.252355426 SAH1 -- methionine biosynthesis -- Adenosylhomocysteinase YKR042W UTH1 22.3 28 29.2 0.95 0.835223302 iYKR041W 0.307540688 0.461867259 0.149416518 UTH1 -- aging -- the aging processmutants have longer lifespan and better viability upon starvation YGR175C ERG1 8.4 11 29.2 0.95 0.739790533 iYGR175C 0.468855649 0.776137271 0.411338764 "ERG1 -- sterol metabolism -- Squalene monooxygenase (squalene epoxidase), an enzyme of ergosterol biosynthesis pathway" YKL009W MRT4 11.2 14 29 0.9496 0.468270691 iYKL010C 0.795549574 0.480341605 0.488385315 MRT4 -- mRNA decay -- mRNA turnover YHR143W YHR143W 6.8 9 29 0.9496 0.419304477 iYHR142W 0.869708722 0.609649123 0.739278752 YHR143W -- unknown -- unknown function YBL002W HTB2 8.4 11 28.9 0.9492 0.808880532 iYBL003C 0.396439072 0.685451166 0.510546288 "HTB2 -- chromatin structure -- Histone H2B, nearly identical to Htb1p" YGL148W ARO2 8.3 11 28.9 0.9492 0.641114444 iYGL149W 0.30864881 0.854909154 0.150168683 ARO2 -- aromatic amino acid biosynthesis -- Chorismate synthase YOR309C YOR309C 10.8 14 28.5 0.9488 0.279210048 0.053950519 YOR309C -- unknown -- unknown function YJR105W YJR105W 9.5 12 28.5 0.9488 0.751578925 iYJR104C 0.416519472 0.895020947 0.850073225 YJR105W -- unknown -- similarity to ribokinase YLR286C CTS1 10.4 14 28.1 0.9486 1 0.92171916 iYLR286C 0.990830482 0.666209567 0.467828889 CTS1 -- cell wall biogenesis -- Endochitinase YNL135C FPR1 21.3 28 28 0.9484 0.263997487 iYNL135C 0.442238122 0.355588044 0.542458911 "FPR1 -- protein folding -- FK506-binding peptidylprolyl cis-trans isomerase (PPIase) activity, homolog of human FKBP12" YKL182W FAS1 8.4 11 27.9 0.9482 0.570998846 iYKL183W 0.87834074 0.642024333 0.391223683 "FAS1 -- fatty acid metabolism -- Fatty-acyl-CoA synthase, beta chain, contains acetyl transferase, enoyl reductase, enoyl dehydratase, and malonyl/palmitoyl transferase activities in a single polypeptide" YDR077W SED1 28.3 38 27.6 0.9478 0.054261946 iYDR076W 0.768481728 0.07074399 0.340486651 SED1 -- unknown -- Abundant cell surface glycomay contribute to cell wall integrity and stress resistanceoverexpression suppresses growth defect of erd2 YGL225W GOG5 10.7 14 27.6 0.9478 0.611048677 iYGL226W itV(AAC)G3-0 0.323345311 0.62780724 0.451237031 0.116177892 0.539001371 "GOG5 -- protein glycosylation -- Golgi GDP-mannose transporter, member of nucleotide-sugar transporter (NST) family of membrane transporters" YFL045C SEC53 9.4 13 27.5 0.9474 0.740077564 iYFL045C 0.667138938 0.804748226 0.341780377 "SEC53 -- protein glycosylation -- Phosphomannomutase, involved in the synthesis of GDP-mannose and dolichol-phosphate-mannose" YPL028W ERG10 9.1 12 27.5 0.9474 0.536657727 iYPL029W 0.531756491 0.472118959 0.813809217 ERG10 -- sterol metabolism -- Acetyl-CoA acetyltransferase (acetoacetyl-CoA thiolase)first step in mevalonate/sterol pathway YAL005C SSA1 13.4 18 27.4 0.947 0.811316322 iYAL004W 0.496737589 0.733665269 0.285497006 SSA1 -- ER and mitochondrial translocation -- Cytoplasmic chaperone and heat shock HSP70 family YOR224C RPB8 8 11 27.4 0.947 0.081717615 iYOR224C 0.037623873 0.033457249 0.008612078 "RPB8 -- transcription -- Shared subunit of RNA polymerases I, II, and III (ABC14.5)" YDR341C YDR341C 8 11 27.1 0.9468 0.557317019 iYDR341C 0.518680981 0.814471243 0.5255398 "YDR341C -- protein synthesis -- Arginine-tRNA synthetase, member of class I family of aminoacyl-tRNA synthetases" YNL064C YDJ1 14 19 27 0.9466 0.193378663 iYNL064C 0.283131546 0.530398323 "YDJ1 -- mitochondrial and ER protein targeting -- import into mitochondria and ER, homolog of E. coli DnaJ" YER019C-A SBH2 9.2 13 26.8 0.9464 0.563990344 iYER019C-A 0.30579423 0.598289909 0.717128585 "SBH2 -- secretion -- Component of Ssh1p-Sss1p-Sbh2p complex, involved in protein translocation into the endoplasmic reticulum" YDR023W SES1 9.1 13 26.7 0.9462 0.924727241 iYDR022C itV(UAC)D 0.483787303 0.85656946 0.494170328 0.172948971 0.758579409 "SES1 -- protein synthesis -- Seryl-tRNA synthetase, cytoplasmicmember of class II family of aminoacyl-tRNA synthetases" YLR180W SAM1 7.2 10 26.6 0.946 0.589393219 iYLR179C 0.447228947 0.862329435 0.398107469 SAM1 -- methionine metabolism -- S-adenosylmethionine synthetase 1 YHR039C-A 11.1 16 26.5 0.9458 0.295660795 iYHR039C-B 0.412507617 0.143680962 0.22571475 YLL050C COF1 15.4 21 26.4 0.9454 0.885906356 iYLL050C 0.616791898 0.704352835 0.319996773 "COF1 -- cytoskeleton -- Cofilin, actin binding and severing protein" YBR025C YBR025C 12.3 17 26.4 0.9454 0.375846939 iYBR025C 0.564364405 0.702079272 0.232098564 YBR025C -- unknown -- Member of GTP-binding protein family YOR247W SRL1 8.9 13 26 0.945 0.009277259 iYOR246C 0.583827231 0.013647247 0.433390932 SRL1 -- unknown -- similarity to Svs1p YDL153C SAS10 7.1 10 26 0.945 0.151623003 0.268772156 "SAS10 -- silencing -- derepresses HMR, HML and telomeres when overproduced" YAR009C 12.8 18.8 25.8 0.9448 0.357042806 iYAR009C 0.102122868 0.398008722 0.132721468 YML126C HMGS 9.3 13 25.7 0.9444 0.684097757 iYML126C 0.89947136 0.716544325 0.778414132 "HMGS -- sterol metabolism -- 3-hydroxy-3-methylglutaryl coenzyme A synthase, functions in mevalonate synthesis" YML056C YML056C 7.7 11 25.7 0.9444 0.905288862 0.655158506 YML056C -- unknown -- similarity to inosine-5'-monophosphate dehydrogenase YJL034W KAR2 13.4 20 24.7 0.9441 0.790700679 iYJL035C 0.60603853 0.912403111 0.915531097 "KAR2 -- secretion -- Heat shock ER lumen required for protein translocation across the ER membrane and for nuclear fusion, member of HSP70 family of protein chaperones" YML012W ERV25 13.2 20 24.7 0.9441 0.41495255 iYML013C-A 0.276714442 0.560726965 0.13782921 ERV25 -- secretion -- Component of COPII-coated vesicles YLR293C GSP1 11.9 18 24.6 0.9439 0.607653376 iYLR293C 0.653404711 0.888575572 0.368556909 "GSP1 -- nuclear protein targeting -- Ran, a GTP-binding ras superfamily involved in trafficking through nuclear pores" YAL044C GCV3 10.6 16 24.5 0.9435 0.786729466 iYAL044C 0.440544905 0.727149078 0.661934339 "GCV3 -- glycine metabolism -- Glycine decarboxylase hydrogen carrier protein H subunit (glycine cleavage H protein), functions in the pathway for glycine degradation" YOR270C VPH1 10.3 16 24.5 0.9435 0.381480803 iYOR270C 0.388942853 0.242142616 0.200779727 "VPH1 -- vacuolar acidification -- Vacuolar H(+)-ATPase (V-ATPase) 94 kDa subunit of membrane (V0) sector, essential for vacuolar acidification and vacuolar H(+)-ATPase (V-ATPase) activity" YPL273W SAM4 6.2 9 24.3 0.9433 0.764533558 iYPL274W 0.359031565 0.906270305 0.532870856 SAM4 -- unknown -- Putative cobalamin-dependent homocysteine S-methyltransferase YMR217W GUA1 8.1 12 24.1 0.9431 0.461225951 iYMR216C 0.151475731 0.538148444 0.33811504 "GUA1 -- purine metabolism -- GMP synthetase, catalyzes the amination of xanthine monophosphate to guanine monophosphate in the guanine branch of purine biosynthesis pathway" YNL134C YNL134C 8.6 13 24 0.9427 0.403836259 iYNL134C 0.075178411 0.705929745 0.0632083 YNL134C -- unknown -- similarity to C. carbonum toxD gene YGR124W ASN2 8.2 13 24 0.9427 0.642609015 iYGR123C itI(AAU)G 0.355032972 0.296151315 0.813180608 0.486679662 0.245894479 ASN2 -- asparagine biosynthesis -- Asparagine synthetase (L-aspartate YML022W APT1 5.7 9 23.8 0.9425 0.623853211 iYML023C 0.381137647 0.891467127 0.235460192 "APT1 -- purine biosynthesis -- Adenine phosphoribosyltransferase (APRT), may be a heterodimer with Apt2p" YER160C 10 15 23.6 0.9421 0.169103747 0.136951317 YML045W 9 13.5 23.6 0.9421 0.893865222 0.698830409 YOR020C HSP10 12.1 19 23.4 0.9417 0.806430623 iYOR020C-0 iYOR020C-1 0.188996133 0.308224134 0.928371768 0.181495523 0.329672187 "HSP10 -- protein folding -- Mitochondrial chaperonin that cooperates with Hsp60p, counterpart of E. coli GroES" YHR214C-B 9.4 14.5 23.4 0.9417 0.893281269 iYHRCdelta16-0 iYHRCdelta16-A 0.406427068 0.720877175 0.464144551 0.3953529 0.790773229 YPR010C RPA135 5.6 9 23.3 0.9415 0.508615092 iYPR010C tK(CUU)P 0.54721202 0.766473669 0.764297814 0.782605118 0.651556265 RPA135 -- transcription -- RNA polymerase I second largest subunit YER009W NTF2 12.1 19 23.1 0.9407 0.749309611 iYER008C 0.611858725 0.749362297 0.844135802 "NTF2 -- nuclear protein targeting -- Nuclear transport factor, homologous to mammalian cytosolic nuclear import factor NTF2" YHL034C SBP1 9.5 15 23.1 0.9407 0.445072875 iYHL034C 0.5491599 0.464082942 0.209417398 "SBP1 -- RNA processing -- Single-stranded nucleic acid-binding protein associated with small nucleolar RNAs (snoRNAs), contains two RNA recognition (RRM) domains, one ofm highly degenerate" YBL039C URA7 6.6 11 23.1 0.9407 0.471552926 iYBL039C 0.370798854 0.491635688 0.241137609 URA7 -- pyrimidine biosynthesis -- CTP synthasefinal step in pyrimidine biosynthesis pathway YOR004W YOR004W 5.2 8 23.1 0.9407 0.334743054 iYOR003W 0.340826713 0.524239735 0.276315789 YOR004W -- unknown -- unknown function YGR240C PFK1 8.8 14 23 0.9403 0.564858813 iYGR240C 0.623780019 0.661287597 0.412797662 "PFK1 -- glycolysis -- Phosphofructokinase alpha subunit, part of a complex with Pfk2p which catalyze ATP-dependent conversion of fructose-6-phosphate to fructose-1,6-bisphosphate, a key regulatory step in glycolysis" YMR318C YMR318C 8 13 23 0.9403 0.547048794 iYMR318C 0.026719929 0.572635249 0.055636777 YMR318C -- unknown -- similarity to alcohol-dehydrogenases YOR210W RPB10 9.8 16 22.8 0.9399 0.370656794 iYOR209C 0.169128015 0.200934579 0.133122157 "RPB10 -- transcription -- Shared subunit of RNA polymerases I, II, and III (ABC10beta), has zinc-binding domain" YLR197W SIK1 7.3 12 22.8 0.9399 0.773615242 iYLR196W 0.364191433 0.941601689 0.206304868 "SIK1 -- rRNA processing -- Nucleolar protein component of box C/D snoRNPs, which are necessary for 2'-O-methylation of ribosomal RNAs" YPL234C VMA11 9.9 16 22.7 0.9397 0.218034065 iYPL234C 0.602804772 0.09228039 0.759696728 "VMA11 -- vacuolar acidification -- Proteolipid component of vacuolar H(+)-ATPase (V-ATPase), required for Cup5p assembly" YHR020W YHR020W 7.4 12 22.6 0.9389 0.662114914 iYHR019C 0.227939558 0.925139665 0.125420897 "YHR020W -- unknown -- similarity to prolyl-tRNA synthetases, member of class II aminoacyl-tRNA synthetases" YNL300W YNL300W 5.9 10 22.6 0.9389 0.594187118 iYNL301C 0.798203651 0.143915083 0.400388645 YNL300W -- unknown -- weak similarity to Mid2p YGL078C DBP3 5.7 9 22.6 0.9389 iYGL078C 0.529118345 0.341232617 DBP3 -- rRNA processing -- ATP-dependent RNA helicase CA3member of DEAD/DEAH box family YBR092C PHO3 4.9 8 22.6 0.9389 0.634314604 iYBR092C 0.372276825 0.763349104 0.367749825 "PHO3 -- thiamine uptake -- Acid phosphatase, constitutive, thiamine-binding periplasmic space" YNL160W YGP1 14.3 24 22.5 0.9385 0.297857174 iYNL161W-0 iYNL161W-1 0.762148104 0.303972748 0.766959748 0.786337445 0.506214728 YGP1 -- diauxic shift -- Secreted glycoprotein produced in response to nutrient limitation YKL181W PRS1 8 13 22.5 0.9385 0.945064284 iYKL182W 0.81704111 0.881019602 0.446474122 "PRS1 -- purine, pyrimidine, tryptophan and histidine biosynthesis -- Phosphoribosylpyrophosphate synthetase, synthesizes phosphoribosylpyrophosphate (PRPP) from ribose-5' phosphate and ATP, involved in pseudohyphal growth" YER094C PUP3 12.9 21 22.3 0.9383 0.439521716 iYER094C 0.160363637 0.3604296 0.274699428 PUP3 -- protein degradation -- Proteasome subunit beta3_sc YMR083W ADH3 8.1 13 22.2 0.9379 1 0.74364452 iYMR082C-0 iYMR082C-1 0.899019639 0.922161626 0.898403831 0.50052432 0.474231159 "ADH3 -- glycolysis -- Alcohol dehydrogenase III, mitochondrial isozyme, reduces acetaldehyde to ethanol" YMR292W GOT1 5.3 9 22.2 0.9379 0.428477003 iYMR291W 0.537753645 0.406977701 0.421311608 GOT1 -- secretion (putative) -- Membrane ER to Golgi transport YDR086C SSS1 11.5 19 22.1 0.9375 0.775100507 iYDR086C 0.153358391 0.719161879 0.097424504 "SSS1 -- secretion -- Component of Sec61p-Sss1p-Sbh1p complex and the Ssh1p-Sss1p-Sbh2p complex, involved in protein translocation into the endoplasmic reticulum" YPL061W ALD6 8.9 15 22.1 0.9375 0.774470706 iYPL062W 0.089675685 0.7626732 0.118258609 ALD6 -- ethanol utilization -- Cytosolic acetaldehyde dehydrogenase YDR429C TIF35 8.3 14 21.8 0.9373 0.638547572 iYDR429C 0.22870841 0.73025732 0.264257482 "TIF35 -- protein synthesis -- Translation inititation factor eIF3, p33 subunit" YGL220W YGL220W 8.3 14 21.7 0.9371 0.399489917 iYGL221C 0.343419139 0.410445186 0.119803988 YGL220W -- unknown -- weak similarity to Vibrio alginolyticus bolA protein YOR095C RKI1 3.6 6 21.6 0.9369 0.714869949 iYOR095C 0.976495063 0.822585794 0.509506929 RKI1 -- pentose phosphate cycle -- Ribose 5-phosphate ketol-isomerase YLR413W YLR413W 4.8 8 21.4 0.9367 0.809390214 iYLR412W-0 iYLR412W-1 0.819196785 0.829532309 0.885856708 0.724941586 0.631120432 "YLR413W -- unknown -- unknown function, induced during anaerobic growth" YBR249C ARO4 7.5 13 21.2 0.9365 0.728457697 iYBR249C 0.175940978 0.790216289 0.202304222 "ARO4 -- aromatic amino acid biosynthesis -- 2-Dehydro-3-deoxyphosphoheptonate aldolase (3-deoxy-D-arabino-heptulosonate-7-phosphate synthaseDAHP synthase), tyrosine-inhibited" YHR064C PDR13 11 19 21 0.9364 0.664999359 iYHR064C 0.152775413 0.937479858 0.114296624 "PDR13 -- drug resistance -- Pleiotropic drug resistance protein, member of Hsp70 family of heat shock proteins" YER011W TIR1 10.8 19 20.8 0.9358 0.525878709 iYER010C-0 iYER010C-1 0.527797579 0.251308313 0.479300439 0.680606544 0.275584795 "TIR1 -- stress response (putative) -- Stress-induced cell wall mannoprotein, member of seripauperine (PAU) family" YBR121C GRS1 8.6 15 20.8 0.9358 0.473087344 iYBR121C 0.637434979 0.869484553 0.729807367 "GRS1 -- protein synthesis -- Glycyl-tRNA synthetase, also involved in 3'-end formation of mRNA" YOR021C YOR021C 7 12 20.8 0.9358 0.722669742 iYOR021C 0.161631877 0.8832846 0.152166317 YOR021C -- unknown -- unknown function YGR094W VAS1 6.5 12 20.5 0.9356 0.395377328 iYGR093W 0.711215594 0.654077183 0.647093613 "VAS1 -- protein synthesis -- Valyl-tRNA synthetase (mitochondrial and cytoplasmic forms are coded from the same gene), member of class I family of aminoacyl-tRNA synthetases" YBR286W APE3 7.9 14 20.4 0.9352 0.735750462 iYBR285W 0.708059422 0.928939736 0.755328442 "APE3 -- protein degradation -- Aminopeptidase Y (yscIII, APY), major vacuolar aminopeptidase with preference for basic amino acids and proline" YLR065C YLR065C 6.5 12 20.4 0.9352 0.581753269 iYLR065C 0.48670498 0.754731328 0.557748172 YLR065C -- unknown -- unknown function YOR285W YOR285W 10.2 19 20.3 0.9346 0.376881029 iYOR284W 0.503386032 0.636046134 0.667967317 YOR285W -- unknown -- similarity to Drosophila melanogaster heat shock protein 67B2 YOR187W TUF1 7.2 13 20.3 0.9346 0.433036657 iYOR186W 0.639974577 0.57488629 0.428536164 "TUF1 -- protein synthesis -- Translation elongation factor Tu, mitochondrial" YHR133C YHR133C 6.3 11 20.3 0.9346 0.663437536 iYHR133C 0.488321835 0.937669593 0.567391394 "YHR133C -- unknown -- unknown function, has four potential transmembrane domains" YDR497C ITR1 5.2 9 20.2 0.9344 0.361923649 iYDR497C 0.227007501 0.665913653 0.142645003 "ITR1 -- transport -- Myo-inositol permease (major), closely related to Itr2p, member of hexose transporter family of major facilitator superfamily (MFS)" YML039W 7.4 13 20.1 0.934 0.268996046 0.482681564 YAR010C 5.7 11 20.1 0.934 0.509326422 iYARCdelta5 itA(UGC)A 0.758662272 0.498512049 0.650296084 0.362369044 0.695732839 YMR205C PFK2 6.8 13 20 0.9338 0.640522543 iYMR205C 0.796796572 0.472303444 0.418937806 "PFK2 -- glycolysis -- Phosphofructokinase beta subunit, part of a complex with Pfk1p which catalyzes ATP-dependent conversion of fructose-6-phosphate to fructose-1,6-bisphosphate, a key regulatory step in glycolysis" YDR158W HOM2 9.2 17 19.9 0.9332 HOM2 -- threonine and methionine biosynthesis -- Aspartate-semialdehyde dehydrogenase (L-aspartate-beta-semialdehyde YBR012W-A 5.7 11 19.9 0.9332 0.579067142 0.477026555 YGL028C SCW11 3.9 7 19.9 0.9332 0.804037482 iYGL028C 0.477901894 0.698549965 0.174771661 SCW11 -- cell wall biogenesis -- Putative cell wall similarity to Scw10p YDL126C CDC48 10.2 19 19.8 0.9324 0.66463166 iYDL126C 0.312558789 0.477670298 0.231562703 "CDC48 -- ubiquitin mediated degredation -- AAA family of ATPases, required for cell division and homotypic membrane fusion, has two AAA domains" YLR259C HSP60 9.9 19 19.8 0.9324 0.290617701 iYLR259C 0.308902701 0.336932001 0.616679968 "HSP60 -- protein folding -- Mitochondrial chaperonin that cooperates with Hsp10p, homolog of E. coli GroEL" YOL097C WRS1 6.7 13 19.8 0.9324 0.410768373 iYOL097C 0.534158851 0.628075372 0.167877661 WRS1 -- protein synthesis -- Tryptophanyl-tRNA synthetase YMR305C SCW10 5.2 10 19.8 0.9324 0.471320879 iYMR305C 0.599325234 0.768635275 0.824349442 "SCW10 -- cell wall biogenesis -- similarity to Scw4p, Bgl2p and other putative glucanases" YDR454C GUK1 9.9 19 19.7 0.9316 0.667295528 iYDR454C 0.444039925 0.940872792 0.761452514 "GUK1 -- guanine nucleotide metabolism -- Guanylate kinase, carries out conversion of ATP + GMP to ADP + GDP" YML058W SML1 9.8 18 19.7 0.9316 0.660627505 iYML059C 0.495283635 0.369445517 0.18366922 SML1 -- DNA replication (putative) -- negatively affects dNTP pools YJL130C URA2 8.2 15 19.7 0.9316 0.648955487 iYJL130C 0.195400527 0.638228252 0.372418333 "URA2 -- pyrimidine biosynthesis -- Multifunctional pyrimidine biosynthesis pathway, contains glutamine amidotransferase, glutamine-dependent carbamylphosphate synthase (CPSase), dihydroorotase-like (DHOase) domain, and aspartate carbamyltransferase (ATCase)" YMR146C TIF34 7 13 19.7 0.9316 0.628922364 iYMR146C 0.142160826 0.790006988 0.087470072 "TIF34 -- protein synthesis -- Translation initiation factor eIF3, p39 subunithas 2 WD (WD-40) repeats" YMR186W HSC82 7.9 15 19.6 0.9314 0.574712644 iYMR185W 0.555262052 0.241090147 HSC82 -- protein folding -- Chaperonin homologous to E. coli HtpG and mammalian HSP90 YGR282C 15 29 19.2 0.9308 0.808769816 iYGR282C 0.642093416 0.847843075 0.560259511 YDR508C GNP1 7 14 19.2 0.9308 0.546955061 0.364724661 GNP1 -- transport -- Glutamine permeasehigh affinity YBR012W-B 5.5 11 19.2 0.9308 0.51141813 0.294694153 YLR359W ADE13 8.9 17 19.1 0.9302 0.633818549 iYLR358C 0.653089316 0.903399936 0.627998943 "ADE13 -- purine biosynthesis -- Adenylosuccinate lyase, carries out the eighth step in de novo purine biosynthesis" YDL212W SHR3 7.9 15 19.1 0.9302 0.054557228 iYDL213C 0.337575486 0.291061169 "SHR3 -- secretion; protein targeting, plasma membrane -- exit of amino acid permeases from the endoplasmic reticulum and subsequent appearance on the cell surface" YMR051C 5.2 10 19.1 0.9302 0.879771939 iYMRCdelta10 YMRCdelta11 0.454431871 0.722393611 0.429194438 0.334031582 0.769416694 YHR068W DYS1 7.9 15 19 0.9298 0.422525764 iYHR067W 0.52001299 0.698016951 0.487565295 "DYS1 -- hypusine biosynthesis -- Deoxyhypusine synthase, first step in hypusine biosynthesiscarries out the conversion of lysine + spermidine into deoxyhypusine" YKR074W YKR074W 5.2 10 19 0.9298 0.713900686 iYKR073C itK(UUU)K 0.516684506 0.841543635 0.845824598 0.450236566 0.62808642 YKR074W -- unknown -- unknown function YDR343C HXT6 11.1 22 18.9 0.9292 0.247347609 iYDR343C 0.702140756 0.299468257 0.880865734 "HXT6 -- transport -- High-affinity hexose transporter, member of hexose transporter family of major facilitator superfamily (MFS), nearly identical to Hxt7p" YMR260C TIF11 7.1 14 18.9 0.9292 0.491406379 iYMR260C 0.668383577 0.674437364 0.340798739 TIF11 -- protein synthesis -- Translation initiation factor eIF1A YJL196C ELO1 6.5 13 18.9 0.9292 0.492025152 iYJL196C 0.161764036 0.614481244 0.268924626 ELO1 -- fatty acid metabolism -- Fatty acid elongation elongation of tetradecanoic acid (14 YOR122C PFY1 12 24 18.8 0.929 0.367685105 iYOR122C 0.468895186 0.661235909 0.091699155 "PFY1 -- cytoskeleton -- Profilin, can act to prevent actin polymerization and to complex with monomeric actin" YDL022W GPD1 7.6 15 18.7 0.9286 1 0.966648954 0.864324847 "GPD1 -- glycerol metabolism -- Glycerol-3-phosphate dehydrogenase (NAD+), cytoplasmic, involved in glycerol production converting glycerol-3-phosphate and NAD+ to dihydroxyacetone phosphate and NADH" YBR143C SUP45 6.1 12 18.7 0.9286 0.684839439 iYBR143C 0.424999247 0.956344773 0.680686353 "SUP45 -- protein synthesis -- Translational release factor eRF1, interacts with Sup35p (eRF3) to form translational release factor complex, involved in control of translational fidelitycan act as a recessive omnipotent suppressor" YPR103W PRE2 9.8 19 18.6 0.9281 1 0.966280137 iYPR102C 0.993661589 0.448448943 0.262011173 "PRE2 -- protein degradation -- Proteasome subunit beta5_sc (protease yscE subunit Pre2/Prg1), involved in chymotrypsin-like activity of proteasome" YOR007C SGT2 11.6 23 18.6 0.9281 0.441395499 iYOR007C tR(ACG)O 0.257676675 0.828743168 0.777979736 0.302610377 0.478407992 "SGT2 -- unknown -- unknown function, contains tetratricopeptide (TPR) repeats" YBR078W ECM33 6.8 13.5 18.6 0.9281 0.651792756 iYBR077C 0.274647185 0.727357215 0.157032978 "ECM33 -- cell wall biogenesis -- predicted GPI-anchor, involved in cell wall structure or biosynthesis" YJL159W HSP150 10.9 22 18.5 0.9275 0.824496289 iYJL160C-0 iYJL160C-1 0.355272804 0.161684393 0.682442139 0.578354298 0.282494759 "HSP150 -- heat shock response -- Secreted O-glycosylated tolerance to heat shock, member of Pir1/Hsp150p/Pir3 family of proteins with variable number of tandem internal repeats" YMR295C YMR295C 10.8 22 18.5 0.9275 0.710296541 iYMR295C 0.758921214 0.641739824 0.241500399 YMR295C -- unknown -- unknown function YMR131C RSA2 4.9 10 18.5 0.9275 0.448541999 iYMR131C 0.414146422 0.426149922 0.532894737 "RSA2 -- unknown -- ribosome assembly, member of WD (WD-40) repeat family" YKL117W SBA1 11.1 22 18.4 0.9271 0.169552434 iYKLCdelta4 itA(AGC)K1 0.416811032 0.212103888 0.268333897 0.322188205 0.156005485 "SBA1 -- protein folding -- Ste5p-associated protein, putative co-chaperone with Hsp90 family proteins (Hsp82p, Hsc82p)" YGR106C YGR106C 8.2 17 18.4 0.9271 0.298653161 iYGR106C tL(GAG)G 0.431358265 0.64373521 0.826177175 0.784302654 0.514238295 YGR106C -- unknown -- similarity to Vibrio anguillarum chemotaxis methyl transferase PIR YDL137W ARF2 9.5 19 18.3 0.9259 0.984995547 iYDL138W 0.82981513 0.931374969 0.47477989 ARF2 -- secretion -- GTP-binding arf family (ras superfamily) involved in assembly of coated vesicles of secretory system YGL200C EMP24 8.1 16 18.3 0.9259 0.677837138 iYGL200C 0.301932726 0.350339964 EMP24 -- secretion -- Component of COPII-coated vesicles possibly involved in cargo sorting YJR027W 6.2 12.5 18.3 0.9259 0.53231513 0.54932645 YER025W GCD11 5.8 12 18.3 0.9259 0.711805318 iYER024W 0.211656048 0.806860426 0.184317847 GCD11 -- protein synthesis -- Translation initiation factor eIF2 gamma subunit YJR028W 5.2 10 18.3 0.9259 0.87531152 0.611700815 YGL032C AGA2 3.1 6 18.3 0.9259 0.062427944 IntYGL033W iYGL032C 0.484832874 0.459559044 0.06501573 0.422173566 0.171654433 AGA2 -- mating -- a-Agglutinin binding subunit YDR037W KRS1 8.1 16 18.2 0.9253 1 0.943503862 iYDR036C 0.98692732 0.798098614 0.255800726 "KRS1 -- protein synthesis -- Lysyl-tRNA synthetase, cytoplasmic" YDR188W CCT6 5.7 12 18.2 0.9253 1 0.972071621 0.86063191 "CCT6 -- protein folding -- Component of chaperonin-containing T-complex (TCP ring complex, TRiC)distantly related to Tcp1p and to Hsp60 family" YNL007C SIS1 9.1 19 18.2 0.9253 0.674192634 iYNL007C 0.692632051 0.449155296 0.474415205 "SIS1 -- translation -- initiation of translation, member of DnaJ family of protein chaperones" YPR165W RHO1 9 19 18.1 0.9251 0.201686192 iYPR164W 0.315679313 0.139619883 0.513269339 "RHO1 -- signaling -- GTP-binding protein required to activate the PKC1 pathway and beta-1,3-glucan synthase, member of rho family of ras superfamily" YPR028W YIP2 10.6 22 18 0.9249 0.849529847 iYPR027C tF(GAA)P2 0.514966005 0.682154939 0.923126563 0.502872592 0.402553871 YIP2 -- unknown -- similarity to human polyposis locus protein 1 YPL231W FAS2 6.3 13 17.9 0.9245 0.350396863 iYPL232W 0.569706734 0.228424179 0.756416504 "FAS2 -- fatty acid metabolism -- Fatty-acyl-CoA synthase, alpha chaincontains acyl carrier protein, beta-ketoacyl reductase, and beta-ketoacyl synthase" YNR053C YNR053C 5.2 11 17.9 0.9245 0.633963198 iYNR053C 0.372867778 0.668746154 0.400097466 "YNR053C -- unknown -- Nuclear unknown function, has similarity to human breast tumor-associated autoantigen" YPR110C RPC40 5.7 12 17.8 0.9239 1 0.875906003 iYPR110C 0.953609909 0.51707901 0.316850851 RPC40 -- transcription -- Shared subunit of RNA polymerases I and III YFL038C YPT1 12.3 26 17.8 0.9239 0.606140471 iYFL038C 0.232065054 0.702789435 0.072510474 "YPT1 -- secretion -- GTP-binding vesicle transport from ER to Golgi and within the Golgi stack, member of rab family in the ras superfamily" YMR050C 7.5 15 17.8 0.9239 0.240246074 0.065832688 YGL054C ERV14 6.4 13 17.7 0.9235 0.881611591 iYGL054C iYGLWdelta7 0.567861576 0.356137067 0.941956742 0.460763777 0.363599742 "ERV14 -- polarized growth (putative) -- ER-derived vesicles, with similarity to Drosophila melanogaster cni protein" YJR148W BAT2 6.1 13 17.7 0.9235 0.63699717 iYJR147W 0.07093998 0.799555665 0.010244414 BAT2 -- branched chain amino acid biosynthesis -- Cytosolic branched-chain amino acid transaminase YKL145W RPT1 8.2 17 17.6 0.9229 0.58385128 iYKL146W 0.174086831 0.634051874 0.547228794 "RPT1 -- protein degradation, ubiquitin-mediated -- ATPase component of 26S proteasome complex, member of AAA family of ATPases" YMR243C ZRC1 6.2 13 17.6 0.9229 0.975805797 iYMR243C 0.970519638 0.871307496 0.646629858 ZRC1 -- zinc and cadmium ion homeostasis -- Zinc- and cadmium-resistance protein YHR170W NMD3 5.2 11 17.6 0.9229 0.50502805 iYHR169W 0.021288651 0.940236065 0.078890054 "NMD3 -- mRNA decay, nonsense-mediated -- Nam7p/Upf1p-interacting stable 60S ribosomal subunit formation" YAL035W YAL035W 8.8 19 17.5 0.9223 0.61496349 iYAL036C 0.45051853 0.279655289 0.598130841 "YAL035W -- unknown -- Translation initiation factor 2, has similarity to bacterial IF2" YMR002W YMR002W 7.5 16 17.5 0.9223 0.49199608 iYMR001C 0.246608765 0.560266407 0.414924182 YMR002W -- unknown -- unknown function YER138C 7.3 15 17.5 0.9223 0.375731295 0.473503591 YPR187W RPO26 5.9 13 17.4 0.9217 0.149189035 iYPR186C 0.502021094 0.218300008 0.340813078 "RPO26 -- transcription -- Shared subunit of RNA polymerases I, II, and III (ABC23)" YJL148W RPA34 5.3 11 17.4 0.9217 0.799479001 iYJL149W snR128 0.721169552 0.692123051 0.270468197 0.559958342 0.464225216 "RPA34 -- transcription -- RNA polymerase I subunit, not shared with other RNA polymerases" YKL096W CWP1 4.3 9 17.4 0.9217 0.722480729 iYKL097W-A-0 iYKL097W-A-1 0.750455267 0.814303883 0.867446394 0.315640881 0.56735834 "CWP1 -- cell wall protein -- Mannocell wall, member of seripauperin (PAU) family" YJR029W 6.5 14.5 17.3 0.9211 0.209008646 0.095426313 YFR033C QCR6 5.4 12 17.3 0.9211 0.816500622 iYFR033C 0.789834235 0.101995211 0.256025539 QCR6 -- oxidative phosphorylation -- Ubiquinol cytochrome-c reductase subunit 6component of ubiquinol cytochrome-c reductase complex (cytochrome bc1 complex) YJR143C PMT4 4.5 10 17.3 0.9211 0.810178528 iYJR143C 0.596376779 0.956413149 0.447936972 PMT4 -- protein glycosylation -- Mannosyltransferase (dolichyl phosphate-D-mannose YLR367W RPS22B 13.6 28.8 17.2 0.9202 1 0.953522186 iYLR366W SNR44 0.826921839 0.795082652 0.966699155 0.928208438 0.649108655 "RPS22B -- protein synthesis -- RIbosomal protein S22 (yeast S24rp50YS22rat S15A), nearly identical to Rps22Ap" YBR162C YBR162C 7.4 16 17.2 0.9202 0.453652896 iYBR162C 0.186916873 0.708857442 0.267295597 YBR162C -- unknown -- similarity to Aga1p YKL054C YKL054C 6.6 14 17.2 0.9202 0.100213331 iYKL054C YKL053C-A 0.669039019 0.487910611 0.051088369 0.552114924 0.670550678 "YKL054C -- unknown -- unknown function, glutamine rich" YLR342W FKS1 6.5 14 17.2 0.9202 0.63992493 iYLR341W 0.399610295 0.374388539 0.397335932 "FKS1 -- cell wall biogenesis -- Component of beta-1,3-glucan synthase, probably functions as an alternate subunit with Gsc2p with which it has strong similarity" YKL192C ACP1 6.2 13 17.2 0.9202 0.604388833 iYKL192C 0.338008263 0.66484524 0.683240223 "ACP1 -- fatty acid biosynthesis -- Acyl carrier protein, component of mitochondrial type II fatty acid synthase" YBR158W CST13 5.2 11 17.1 0.92 0.6665962 iYBR157C-0 iYBR157C-1 0.174167472 0.59197754 0.866001596 0.313366002 0.683438155 CST13 -- Cu2+ ion homeostasis (putative) -- optimal growth and germination rate YHR128W FUR1 5.5 12 17 0.9196 0.902881308 iYHR127W 0.510283446 0.899121325 0.344021914 "FUR1 -- pyrimidine salvage pathway -- Uracil phosphoribosyltransferase, part of pyrimidine salvage pathway" YLR420W URA4 4 9 17 0.9196 0.289297797 iYLR419W itL(UAA)L 0.676984646 0.645950911 0.364805123 0.410055866 0.563523433 "URA4 -- pyrimidine biosynthesis -- Dihydroorotase, third step in pyrimidine biosynthesis pathway" YPR149W NCE102 15.5 34 16.9 0.9192 0.828048822 iYPR148C-0 iYPR148C-1 0.636746785 0.785354344 0.93802794 0.657232173 0.343466108 "NCE102 -- secretion, non-classical -- non-classical export pathway for proteins that lack standard secretory signal sequences" YGR135W PRE9 8.3 18 16.9 0.9192 0.4513156 iYGR134W 0.215314332 0.615903184 0.251707397 PRE9 -- protein degradation -- Proteasome subunit alpha3_sc YMR297W PRC1 7.7 17 16.8 0.9186 0.569114266 iYMR296C 0.494539373 0.950692878 0.310510071 "PRC1 -- sporulation -- Carboxypeptidase Y (CPY/yscY), serine-type protease" YDL182W LYS20 4.8 11 16.8 0.9186 0.780469734 iYDL183C-0 iYDL183C-1 0.885366271 0.361871438 0.810542279 0.777015164 0.315139701 "LYS20 -- lysine biosynthesis -- Homocitrate synthase isoenzyme, involved in lysine biosynthesis" YJR070C YJR070C 4 9 16.8 0.9186 0.684416857 0.981643925 YJR070C -- unknown -- unknown function YNL113W RPC19 5.5 12 16.7 0.9182 0.069299925 0.082197764 RPC19 -- transcription -- Shared subunit of RNA polymerases I and III YJR026W 4.8 11 16.7 0.9182 0.893253839 iYJR025C 0.349773688 0.601662141 0.175526337 YFL035C-B 7.3 16 16.6 0.9176 YOR276W CAF20 7.3 16 16.6 0.9176 0.549692649 iYOR275C 0.538306938 0.55553763 0.590636057 CAF20 -- protein synthesis -- mRNA cap-binding protein (eIF4F) 20K subunit YBR088C POL30 5.8 13 16.6 0.9176 0.504405964 0.689450897 "POL30 -- DNA replication -- Proliferating cell nuclear antigen (PCNA), required for DNA synthesis and DNA repair" YIL043C CBR1 10.1 23 16.5 0.9168 0.275542525 iYIL043C 0.482896906 0.865602554 0.209084177 "CBR1 -- aminosugars metabolism -- Cytochrome b5 reductase, converts 2 ferricytochrome B5 + NADH to 2 ferrocytochrome B5 + NAD(+), uses FAD cofactor" YMR173W-A 8.1 18 16.5 0.9168 0.235083553 0.391672838 YER148W SPT15 7.1 16 16.5 0.9168 0.32416975 iYER147C 0.236231547 0.399036837 0.028589994 "SPT15 -- transcription -- TATA-binding component of RNA polymerases I, II, and IIIpart of initiation factors TFIID and TFIIIB" YNL259C ATX1 4.3 9 16.5 0.9168 0.841571087 iYNL259C 0.401846609 0.647498376 0.210746604 ATX1 -- oxidative stress response -- Antioxidant protein and metal homeostasis factorfunctions in a copper trafficking pathway YDL125C HNT1 9.1 20.5 16.4 0.916 0.810280538 iYDL125C 0.512831092 0.978719948 0.809901994 HNT1 -- unknown -- Member of HIT family of Zn-binding proteins and the histidine triad nucleotide-binding protein family YDR172W SUP35 7.7 17 16.4 0.916 0.338887737 iYDR171W 0.565468008 0.753786658 0.731156595 "SUP35 -- protein synthesis -- Translational release factor eRF3, interacts with Sup45p (eRF1) to form translational release factor complex, also a prion responsible for the [PSI+] determinant" YDR304C CYP5 7.1 16 16.4 0.916 0.206486547 iYDR304C 0.228431663 0.354110136 0.248988472 "CYP5 -- protein folding -- Cyclophilin (peptidylprolyl cis-trans isomerase or PPIase) of endoplasmic reticulum, has a HDEL sequence for retention in the endoplasmic reticulum" YGR189C CRH1 6.2 14 16.4 0.916 0.383464962 iYGR189C itW(CCA)G2 0.404238045 0.56589679 0.408060654 0.262983831 0.602078634 CRH1 -- cell wall biogenesis (putative) -- Cell wall protein YOL061W PRS5 5.9 14 16.3 0.9158 0.841851106 iYOL062C 0.242611405 0.963100226 0.133203379 "PRS5 -- purine, pyrimidine, tryptophan and histidine biosynthesis -- Phosphoribosylpyrophosphate synthetase (ribose-phosphate pyrophosphokinase)" YNL339C YRF1-6 6.4 15 16.2 0.9148 0.919262095 iYNL339C 0.994757203 0.078529001 0.032185206 YRF1-6 -- unknown -- near identity to other subtelomerically-encoded proteins YER087C-A SBH1 6.3 14 16.2 0.9148 0.317299364 iYER087C-A 0.855522397 0.35360941 0.269828791 "SBH1 -- secretion -- Component of Sec61p-Sss1p-Sbh1p complex, involved in protein translocation into the endoplasmic reticulum" YPR113W PIS1 5.4 12 16.2 0.9148 0.03155508 iYPR112C 0.202915079 0.103622403 0.151904263 PIS1 -- phospholipid metabolism -- CDP-diacylglycerol-inositol 3-phosphatidyltransferase; YDR381W YRA1 4.8 11 16.2 0.9148 0.779155884 iYDR380W IntYDR381W 0.50534853 0.87124589 0.541594668 0.520224172 0.681865828 YRA1 -- mRNA processing -- RNA YPL211W NIP7 4.5 10 16.2 0.9148 0.281716929 iYPL212C 0.598436977 0.228252195 0.483337448 NIP7 -- rRNA processing -- Nucleolar efficient 60S ribosome subunit biogenesis YMR246W FAA4 5.5 13 16.1 0.9146 0.878101563 iYMR245W 0.38178927 0.837069526 0.261252366 FAA4 -- fatty acid metabolism -- Acyl-CoA synthase (long-chain fatty acid CoA ligase)contributes to activation of imported myristate YCL064C CHA1 4.5 10 16 0.9142 0.95339386 iYCL064C 0.377781853 0.467916999 0.186380534 CHA1 -- hydroxy amino acid metabolism -- L-serine/L-threonine deaminase YPR124W CTR1 4.3 10 16 0.9142 0.414060689 0.546733054 CTR1 -- transport -- Copper transport high-affinity uptake of copper YAL012W CYS3 8.9 21 15.9 0.9134 0.534264802 iYAL013W 0.17605463 0.697774529 0.133464988 "CYS3 -- methionine biosynthesis -- Cystathionine gamma-lyase, generates cysteine from cystathionine" YPL106C SSE1 8 18 15.9 0.9134 0.383770997 iYPL106C 0.577791473 0.629426474 0.470949721 "SSE1 -- calmodulin signaling -- Heat shock HSP70 family, multicopy suppressor of mutants with hyperactivated ras/cAMP pathway" YOR230W WTM1 7 16 15.9 0.9134 0.527497732 iYOR229W 0.25379078 0.656691135 0.459546665 WTM1 -- meiosis -- Transcriptional modulator involved in meiotic regulation and silencing YIL123W SIM1 5.8 14 15.9 0.9134 0.463911667 iYIL124W 0.290570956 0.132960894 0.307927812 SIM1 -- cell cycle -- the aging process and in regulation of cell cycle YGR180C RNR4 8.9 21 15.8 0.9128 1 0.912420715 iYGR180C itL(CAA)G3 0.942690627 0.562148257 0.898132148 0.254061079 0.395051875 "RNR4 -- DNA replication -- Component of ribonucleotide reductase (ribonucleoside-diphosphate reductase) small subunit, which is comprised of an Rnr2p-Rnr4p heterodimer" YMR308C PSE1 6.1 14 15.8 0.9128 0.684103076 iYMR308C 0.116466742 0.826861102 0.284334843 PSE1 -- nuclear protein targeting -- Beta-Karyopherin involved in nuclear import of ribosomal and other nuclear proteins YKL081W TEF4 4.5 10 15.8 0.9128 0.911651378 iYKL082C 0.866197137 0.929584273 0.189747387 TEF4 -- protein synthesis -- Translation elongation factor EF-1gamma YGL105W ARC1 9.2 22 15.7 0.9117 0.756828055 iYGL106W 0.46397608 0.594418004 0.343990217 ARC1 -- tRNA aminoacylation -- Cofactor for methionyl- and glutamyl-tRNA synthetases and G4 quadruplex nucleic acid binding protein YCR034W FEN1 6.1 14 15.7 0.9117 0.57786991 iYCR033W 0.040278014 0.678558385 0.0444282 FEN1 -- cell wall biogenesis -- the elongation of fatty acids up to 24 carbons YOR335C ALA1 5.2 12 15.7 0.9117 0.73992704 iYOR335C 0.169836688 0.478153542 0.276624395 "ALA1 -- protein synthesis -- Alanyl-tRNA synthetase, cytoplasmic" YDR062W LCB2 4.9 12 15.7 0.9117 0.838250663 iYDR061W 0.880056904 0.550032227 0.784836393 "LCB2 -- sphingolipid biosynthesis -- Subunit of serine C-palmitoyltransferase, first step in sphingolipid biosynthesis, and suppressor of calcium-sensitivity of csg2" YNR018W YNR018W 4.5 11 15.7 0.9117 0.49241914 iYNR017W 0.658940832 0.614422844 0.323549965 YNR018W -- unknown -- unknown function YNL065W YNL065W 4 10 15.7 0.9117 0.373493109 iYNL066W 0.37855929 0.557477289 0.572368962 YNL065W -- unknown -- Member of multidrug-resistance 12-spanner family of major facilitator superfamily (MFS-MDR) YGL245W YGL245W 9.8 23 15.6 0.9111 0.68359528 iYGL246C 0.233313939 0.960201429 0.228810854 "YGL245W -- protein synthesis -- Glutamyl-tRNA synthetase, member of class I aminoacyl tRNA synthetase family" YML040W 4.6 11 15.6 0.9111 0.912601205 iYML041C tP(UGG)M 0.595693264 0.551479976 0.73106671 0.770222365 0.524740623 YLR432W YLR432W 3.8 9 15.6 0.9111 0.975318665 iYLR431C 0.623571011 0.397035127 0.449161426 YLR432W -- unknown -- highly similar to Yhr216p and inosine-5'-monophosphate dehydrogenase of human and E. coli YNL255C GIS2 6.4 15 15.5 0.9105 0.845942459 iYNL255C 0.381713893 0.773277812 0.217478053 GIS2 -- unknown -- Protein possibly involved in cytoplasmic ribosome functionhas similarity to nucleic acid binding proteins YPR016C CDC95 5.3 13 15.5 0.9105 0.676534465 iYPR016C 0.51766529 0.617051013 0.124546261 CDC95 -- ribosome biogenesis (putative) -- Translation initiation factor 6 YOR271C YOR271C 4 10 15.5 0.9105 0.189476501 iYOR271C SNR8 0.516565379 0.676619441 0.516113439 0.557557805 0.32016786 "YOR271C -- unknown -- similarity to rat tricarboxylate carrier, member of mitochondrial tricarboxylate carrier family of membrane transporters" YJL026W RNR2 4.2 10 15.4 0.9093 1 0.932544145 iYJL027C 0.954392896 0.84851477 0.496996626 "RNR2 -- DNA replication -- Component of ribonucleotide reductase (ribonucleoside-diphosphate reductase) small subunit, which is comprised of an Rnr2p-Rnr4p heterodimer" YPR036W VMA13 7.4 18 15.4 0.9093 0.23309376 iYPR035W 0.227522952 0.540892193 0.160966148 "VMA13 -- vacuolar acidification -- Vacuolar H(+)-ATPase (V-ATPase) 54 kDa subunit of V1 sector, required for V-ATPase activity" YHR025W THR1 6.7 16 15.4 0.9093 0.324500515 iYHR024C 0.509788834 0.49803248 0.389622946 THR1 -- threonine biosynthesis -- Homoserine kinase (ATP YGR296W YRF1-3 6.2 15 15.4 0.9093 0.920177612 iYGR295C-0 iYGR295C-1 0.992972767 0.997490691 0.222346369 0.323992853 0.002715379 YRF1-3 -- unknown -- similarity to other subtelomerically-encoded proteins including Yer190p YHR219W YHR219W 6.1 15 15.4 0.9093 0.954131638 iYHR218W 0.731705907 0.298324022 0.011293055 YHR219W -- unknown -- near identity to other subtelomerically-encoded proteins YJL080C SCP160 4.7 11 15.4 0.9093 0.3087273 iYJL080C 0.513628277 0.436086991 0.439977441 "SCP160 -- mitosis, chromosome transmission -- control of mitotic chromosome transmission, contains 14 KH motifs found in RNA-binding proteins such as Mer1p and mouse hnRNP X" YOL038W PRE6 7 17 15.3 0.9089 0.601765819 iYOL039W 0.868625546 0.76623056 0.449336129 PRE6 -- protein degradation -- Proteasome subunit alpha4_sc YHR143W-A RPC10 6.5 16 15.3 0.9089 0.18363483 iYHR143W 0.300794996 0.137270551 0.13487134 "RPC10 -- transcription -- Shared subunit of RNA polymerases I, II, and III (ABC10alpha), has zinc-binding domain" YPL283C YRF1-7 5.8 14 15.2 0.9085 0.812605515 iYPL283C-0 iYPL283C-1 0.99725631 0.996368794 0.197792459 0.02537909 0.009921755 "YRF1-7 -- unknown -- near identity to other subtelomerically-encoded protein, including Ygr296p" YNL220W ADE12 4.6 11 15.2 0.9085 0.852137541 iYNL221C 0.03292043 0.934901708 0.133629556 "ADE12 -- purine biosynthesis -- Adenylosuccinate synthetase, carries out addition of aspartic acid to IMP with GTP hydrolysis" YDR342C HXT7 9.9 24 15.1 0.9075 0.427892555 iYDR342C-0 iYDR342C-1 0.179312114 0.511910684 0.42944129 0.245126706 0.718242365 "HXT7 -- transport -- High-affinity hexose transporter, member of hexose transporter family of major facilitator superfamily (MFS), nearly identical to Hxt6p" YLR060W FRS1 7.6 19 15.1 0.9075 0.928068263 iYLR059C 0.530445635 0.672508846 0.336460133 "FRS1 -- protein synthesis -- Phenylalanyl-tRNA synthetase, alpha subunit, cytoplasmic" YPL218W SAR1 5.8 14 15.1 0.9075 0.574486917 iYPL219W 0.140021067 0.301997701 0.074211503 "SAR1 -- secretion -- Component of COPII coat of vesicles involved in endoplasmic reticulum to Golgi transport, GTP-binding arf family in the ras superfamily" YER036C YER036C 5.6 14 15.1 0.9075 0.843461716 iYER036C 0.553555565 0.92444095 0.314924182 YER036C -- unknown -- Member of non-transporter group of ATP-binding cassette (ABC) superfamily YLR467W YRF1-5 5.6 14 15.1 0.9075 0.964746041 iYLR466W 0.997341178 0.359936153 0.138626834 "YRF1-5 -- unknown -- Y'helicase with near identity to other subtelomerically-encoded proteins including Yer189p, Yml133p, and Yjl225p" YLR466W YRF1-4 5.6 14 15 0.9071 0.935927325 0.410027952 YRF1-4 -- unknown -- similarity to other subtelomerically-coded Y'-helicase proteins YDL051W LHP1 4.4 11 15 0.9071 0.532985652 iYDL052C 0.364492998 0.505618219 0.144882537 "LHP1 -- unknown -- homolog to human La autoantigen which binds to and stabilizes pre-tRNA for 3' endonucleolytic cleavage, has an RNA recognition (RRM) domain" YBR082C UBC4 9.7 24 14.9 0.9063 0.385891593 iYBR082C-0 iYBR082C-1 0.691274081 0.237478897 0.514046289 0.624203818 0.865054797 "UBC4 -- protein degradation, ubiquitin-mediated -- Ubiquitin-conjugating (E2) enzymetogether with Ubc5p is responsible for the majority of ubiquitin-dependent protein degradation of short-lived and abnormal proteins" YER190W YRF1-2 5.9 15 14.9 0.9063 0.953996325 0.464711569 YRF1-2 -- unknown -- similarity to other subtelomerically-encoded proteins including Yil177p YHR208W BAT1 5.6 14 14.9 0.9063 0.820134764 iYHR207C 0.331297962 0.964782358 0.723884811 BAT1 -- branched chain amino acid degradation -- Mitochondrial branched-chain amino acid transaminase YNL110C YNL110C 4.7 12 14.9 0.9063 0.267081486 iYNL110C 0.248269586 0.155147646 0.14574762 "YNL110C -- unknown -- unknown function, contains one RNA recognition (RRM) domain" YPR033C HTS1 5.8 15 14.8 0.9061 0.322343381 iYPR033C 0.134331049 0.663063644 0.068460462 "HTS1 -- protein synthesis -- Histidyl-tRNA synthetase, mitochondrial and cytoplasmic" YJL191W RPS14B 7.9 20 14.7 0.9049 1 1 0.979153526 iYJL192C 0.979489177 0.982391179 0.718175959 "RPS14B -- protein synthesis -- Ribosomal protein S14B (rp59E. coli S11rat and human S14), nearly identical to Rps14Ap" YOR248W YOR248W 5.2 13 14.7 0.9049 0.003283327 0.01635514 YOR248W -- unknown -- unknown function YLR153C ACS2 4.6 12 14.7 0.9049 0.565879927 iYLR153C 0.192035298 0.572152341 0.070999854 ACS2 -- acetyl-CoA biosynthesis -- Acetyl-CoA synthetase YLR009W YLR009W 4.2 10 14.7 0.9049 0.251363411 iYLR008C 0.115557319 0.33516994 0.187157589 YLR009W -- protein synthesis -- Possible ribosomal similarity to ribosomal protein L24 YOR212W STE4 4 10 14.7 0.9049 0.504014444 iYOR211C 0.378113733 0.567996808 0.704629943 "STE4 -- signaling, pheromone pathway -- Beta subunit of guanine nucleotide-binding mediates signal transduction by pheromones, member of WD (WD-40) repeat family" YJR024C YJR024C 3.7 9 14.7 0.9049 0.295763325 iYJR024C 0.632963084 0.55626901 0.39011181 "YJR024C -- unknown -- unknown function, has similarity to enterobacterial L-ribose-5-phosphate 4-epimerases" YNL066W SUN4 3.3 8 14.6 0.9044 1 0.548725142 iYNL067W 0.92305359 0.76397624 0.659603609 SUN4 -- aging -- the aging process YPL160W CDC60 4.8 12 14.6 0.9044 0.587508823 iYPL161C 0.751955933 0.593619078 0.818773234 "CDC60 -- protein synthesis -- Leucyl-tRNA synthetase, cytoplasmic" YAL059W ECM1 3.4 8 14.6 0.9044 0.389431263 iYAL060W 0.67526952 0.337941249 0.63788442 ECM1 -- cell wall biogenesis -- Protein possibly involved in cell wall structure or biosynthesis YPL010W RET3 6.3 16 14.5 0.9032 0.738016428 iYPL011C 0.517983275 0.794573025 0.443832984 RET3 -- secretion -- Coatomer (COPI) complex zeta chain (zeta-COP) of secretory pathway vesiclesrequired for retrograde Golgi to endoplasmic reticulum transport YDR045C RPC11 5.3 13 14.5 0.9032 0.484189633 iYDR045C 0.384994568 0.394981413 0.304751149 "RPC11 -- transcription -- RNA polymerase III subunit C11, required for RNA cleavage activity and transcription termination" YLR229C CDC42 5.3 13 14.5 0.9032 0.4968592 0.769686497 "CDC42 -- signaling, filamentous or polarized growth -- Rho-type GTPase involved in bud site assembly and cell polarity, member of rho family of ras superfamily" YPR163C TIF3 5.2 13 14.5 0.9032 0.229423693 iYPR163C 0.532701959 0.100104864 0.343470194 TIF3 -- protein synthesis -- Translation initiation factor eIF4Bhas 1 RNA recognition (RRM) domain YOL002C YOL002C 3.5 9 14.5 0.9032 0.190464627 iYOL002C 0.217319451 0.704515919 YOL002C -- unknown -- unknown function YNL141W AAH1 2.5 6 14.5 0.9032 0.220492802 iYNL142W 0.616870356 0.475179569 0.553496616 "AAH1 -- purine metabolism -- Adenine deaminase (adenine aminohydrolase), enzyme of purine salvage pathwayhas similarity to adenosine deaminases" YBL076C ILS1 5.8 15 14.4 0.902 0.693345165 iYBL076C 0.721861726 0.865157148 0.369202226 "ILS1 -- protein synthesis -- Isoleucyl-tRNA synthetase, cytoplasmic" YBR154C RPB5 4.9 13 14.4 0.902 0.608560394 iYBR154C 0.740325109 0.723318828 0.474035395 "RPB5 -- transcription -- Shared subunit of RNA polymerases I, II, and III (ABC27)" YBR187W YBR187W 4.6 12 14.4 0.902 0.922064737 iYBR186W 0.693021518 0.506687077 0.586604131 YBR187W -- unknown -- similarity to ND5 and PSB2 YNR021W YNR021W 4.4 11 14.4 0.902 0.578379191 iYNR020C 0.489209578 0.705666401 0.41106818 YNR021W -- unknown -- unknown function YNL248C RPA49 3.9 10 14.4 0.902 0.459196303 iYNL248C 0.299300587 0.862344455 0.340079034 RPA49 -- transcription -- RNA polymerase I third largest subunit YGR103W YGR103W 3.4 9 14.4 0.902 0.213520705 iYGR102C 0.388843515 0.465682362 0.620281131 YGR103W -- unknown -- Nuclear unknow function with similarity to zebrafish pescadillo YNL044W YIP3 5.5 14 14.3 0.9012 0.476688239 iYNL045W 0.603990469 0.809873356 0.660552061 YIP3 -- unknown -- unknown function YER165W PAB1 5.3 14 14.3 0.9012 0.556633574 iYER164W 0.497709587 0.864644852 0.29579737 "PAB1 -- mRNA 3'-end processing -- Poly(A)-binding cytoplasm and nucleus, part of 3'-end RNA-processing complex (cleavage factor I), has 4 RNA recognition (RRM) domains" YLR303W MET17 3.8 10 14.3 0.9012 0.487859718 0.80407058 MET17 -- methionine biosynthesis -- O-acetylhomoserine sulfhydrylase (OAH SHLase)converts O-acetylhomoserine into homocysteine YNL186W UBP10 3.6 9 14.3 0.9012 0.36378548 iYNL187W 0.383406642 0.437350359 0.329658493 "UBP10 -- protein degradation, ubiquitin-mediated -- Ubiquitin C-terminal hydrolaseinvolved in telomeric silencing" YGL012W ERG4 6.6 17 14.2 0.9006 0.719619556 iYGL013C 0.642780309 0.779758512 0.611373166 ERG4 -- sterol metabolism -- Sterol C-24 (28) reductase YDR139C RUB1 5.7 14.5 14.2 0.9006 0.501122381 iYDR139C 0.149855978 0.768169718 0.235324948 "RUB1 -- protein degradation -- Ubiquitin-related protein, becomes conjugated to other proteins including Cdc53p in a process requiring Uba3p, Ula1p and Ubc12p" YLR285W YLR285W 3.7 10 14.2 0.9006 0.669062965 iYLR284C 0.455280746 0.734364081 0.526618848 YLR285W -- unknown -- unknown function YEL046C GLY1 5.2 14 14.1 0.9 1 0.936902573 0.753806238 "GLY1 -- glycine, serine, and threonine metabolism -- Threonine aldolase, required for glycine biosynthesis" YOR099W KTR1 6.1 16 14.1 0.9 0.652014686 iYOR098C 0.426588612 0.731125299 0.736595167 KTR1 -- protein glycosylation -- Mannosyltransferase of KRE2 family involved in N-linked and O-linked glycosylation YDR545W YRF1-1 5.5 14 14.1 0.9 0.939363925 iYDR544C 0.997659272 0.186890838 0.12959763 "YRF1-1 -- unknown -- near identity to the family of subtelomerically-encoded proteins including Yil177p, Yhl049p, and Yjl225p" YJR064W CCT5 5.8 15 14 0.8994 0.631771433 iYJR063W 0.982275218 CCT5 -- protein targeting -- Component of chaperonin-containing T-complex (TCP ring complex and TRiC)homologous to mammalian CCT family of chaperonin proteins YGR061C ADE6 4.7 12 14 0.8994 0.356574044 iYGR061C 0.761998957 0.352504638 0.715758211 "ADE6 -- purine biosynthesis -- 5'-phosphoribosylformyl glycinamidine synthetase, has glutamine amidotransferase domain and aminator domain" YOR145C YOR145C 3.6 10 14 0.8994 0.314741202 0.45351273 YOR145C -- unknown -- unknown function YLR447C VMA6 6.5 17 13.9 0.8988 0.930971238 iYLR447C 0.989642005 0.39065903 0.705422529 "VMA6 -- vacuolar acidification -- Vacuolar H(+)-ATPase (V-ATPase) 36 kDa subunit (subunit D) of membrane (V0) sector, required for V-ATPase assembly" YHR019C DED81 5.4 15 13.9 0.8988 0.834487414 iYHR019C 0.227939558 0.881675307 0.125420897 "DED81 -- protein synthesis -- Asparaginyl-tRNA synthetase, cytoplasmic" YLR395C COX8 5.2 14 13.9 0.8988 0.316691647 iYLR395C 0.793487866 0.572944932 0.717773123 COX8 -- oxidative phosphorylation -- Cytochrome-c oxidase subunit VIII YJR077C MIR1 6.2 16 13.8 0.898 0.620680299 iYJR077C 0.212610549 0.77296165 0.358040606 MIR1 -- transport -- Phosphate transporter of mitochondrial carrier (MCF) family YLR038C COX12 5.8 16 13.8 0.898 0.250402197 iYLR038C 0.221362054 0.417762362 0.164313947 "COX12 -- oxidative phosphorylation -- Cytochrome-c oxidase, subunit VIb" YPR052C NHP6A 4 11 13.8 0.898 0.914555531 0.549568444 NHP6A -- chromatin structure -- Protein related to mammalian nonhistone protein HMG1function redundant with Nhp6Bp YGL029W CGR1 3.6 10 13.8 0.898 0.61799849 iYGL030W 0.803006286 0.419811321 0.603244339 "CGR1 -- unknown -- Predicted coiled-coil protein, down-regulated after diauxic shift" YDL007W RPT2 7.1 19 13.7 0.8972 0.508783933 iYDL008W itT(AGU)D 0.782751145 0.799012466 0.766435707 0.691125087 0.602651173 "RPT2 -- protein degradation -- ATPase component of 26S the proteasome complex, member of AAA family of ATPases" YDL084W SUB2 7.1 19 13.7 0.8972 0.698242813 iYDL085W 0.373923847 0.552753392 0.508812432 "SUB2 -- mRNA splicing -- similarity to nuclear RNA helicases (DEAD/DEAH family), probably involved in pre-mRNA splicing" YGR191W HIP1 5.2 14 13.7 0.8972 0.733689983 0.767625081 HIP1 -- transport -- Histidine permease YER145C FTR1 3.4 9 13.7 0.8972 0.490497438 iYER145C 0.540582037 0.695012995 0.253609744 FTR1 -- transport -- Iron permease that mediates high-affinity iron uptake YBL113C YBL113C 5.6 15 13.6 0.8968 0.976121094 0.573018194 YBL113C -- unknown -- unknown functionsubtelomerically encoded YDR297W SUR2 3.6 10 13.6 0.8968 0.599002758 iYDR296W 0.02930225 0.935736032 0.120195667 SUR2 -- sphingolipid metabolism -- Hydroxylase involved in sphingolipid metabolism YFR004W RPN11 6.2 17 13.5 0.8959 0.203974191 iYFR003C 0.101399638 0.393153954 0.09657245 "RPN11 -- transcription -- 19S regulatory particle of proteasome, has similarity to S. pombe PAD1 gene product" YNL268W LYP1 5.4 15 13.5 0.8959 0.205212292 iYNL269W 0.209593125 0.309018356 0.180584838 LYP1 -- transport -- Lysine-specific permeasehigh affinity YBR252W DUT1 4.7 13 13.5 0.8959 0.832659273 iYBR251W 0.687837348 0.890912572 "DUT1 -- pyrimidine metabolism -- dUTP pyrophosphatase, converts dUTP to dUMP preventing uracil incorporation into DNA" YNR016C ACC1 4.5 12 13.5 0.8959 0.571484618 iYNR016C-0 iYNR016C-1 0.025447048 0.004345731 0.509962088 0.032008558 0.055652486 "ACC1 -- fatty acid metabolism -- Acetyl-CoA carboxylase, first and rate-limiting step in fatty acid biosynthesis pathway" YBR084W MIS1 4 11 13.5 0.8959 0.801059128 iYBR083W 0.156080151 0.965440632 0.121371082 "MIS1 -- folate metabolism -- C1-tetrahydrofolate synthase (trifunctional enzyme), mitochondrial" YOL077C YOL077C 4.3 12 13.4 0.8957 0.52951555 iYOL078W iYOL077C 0.302396744 0.342022386 0.923623304 0.116419594 0.272896249 YOL077C -- unknown -- similarity to C. elegans Kq2H4.3 protein YNL190W YNL190W 9.9 28 13.3 0.8949 1 0.344045881 iYNL191W 0.927923003 0.388011602 0.759259259 YNL190W -- unknown -- unknown function YLR421C YLR421C 7.4 20 13.3 0.8949 0.241824142 iYLR421C 0.252145054 0.221274079 0.435612606 YLR421C -- unknown -- unknown function YPL117C IDI1 4.2 12 13.3 0.8949 0.42258826 iYPL117C 0.163108505 0.331289828 0.118571546 IDI1 -- isoprenoid biosynthesis -- Isopentenyl-diphosphate delta-isomerase (IPP isomerase)catalyzes a step in the cholesterol biosynthesis pathway YGR181W TIM13 4 11 13.3 0.8949 0.156429918 iYGR180C itL(CAA)G3 0.942690627 0.562148257 0.216130604 0.254061079 0.395051875 TIM13 -- mitochondrial protein targeting -- Mitochondrial intermembrane space transport of proteins into the inner membrane YPR204W YPR204W 5.4 15 13.2 0.8947 0.953034672 iYPR203W 0.922745819 0.217450854 0.486384144 "YPR204W -- unknown -- DNA helicase, encoded in the subtelomeric Y' elements" YJR085C YJR085C 8.4 24 13.1 0.8935 0.076060698 iYJR085C 0.076939899 0.50568686 0.442413905 YJR085C -- unknown -- unknown function YBR159W YBR159W 6.1 17 13.1 0.8935 0.635233252 iYBR158W 0.494662036 0.685971349 0.339424951 "YBR159W -- unknown -- Hypothetical transmembrane protein essential for viability, has similarity to human 17beta-hydroxysteroid dehydrogenase (17beta-HSD)" YML001W YPT7 5.1 14 13.1 0.8935 0.634126599 iYML002W 0.273286378 0.805591363 0.125873515 "YPT7 -- endocytosis -- GTP-binding role in protein transport between endosome-like compartments, member of rab family in the ras superfamily" YGR086C YGR086C 4.4 12 13.1 0.8935 0.970229791 iYGR086C 0.730726274 0.862305586 0.552174694 YGR086C -- unknown -- unknown functioninduced by high salt and low pH YMR241W YHM2 4 11 13.1 0.8935 0.638578598 iYMR240C 0.190110411 0.620876018 0.163087304 "YHM2 -- unknown -- Suppressor of abf1 mutant that affects mitochondrial HMG-like DNA-binding protein, member of mitochondrial carrier family (MCF) of membrane transporters" YOR253W YOR253W 4 11 13.1 0.8935 0.803674933 iYOR252W 0.39708642 0.80425601 0.168304866 YOR253W -- unknown -- unknown function YBR221C PDB1 8.5 24 13 0.8931 0.791173866 iYBR221C 0.068997251 0.85575578 0.121636188 "PDB1 -- glycolysis -- Pyruvate dehydrogenase complex, E1-beta subunit" YOR254C SEC63 4.6 13 13 0.8931 0.269425076 iYOR254C 0.125487127 0.505116959 0.039606356 "SEC63 -- secretion -- Component of ER protein-translocation subcomplexwhich includes Sec62p, Sec63p, Sec66p, and Sec72p, member of DnaJ protein family" YJR139C HOM6 5.9 17 12.9 0.8927 1 0.98626209 iYJR139C 0.97508984 0.94877793 0.071961115 HOM6 -- methionine and threonine biosynthesis -- Homoserine dehydrogenase (L-homoserine YML074C NPI46 5.2 15 12.9 0.8927 0.467482321 iYML074C-0 iYML074C-1 0.75378892 0.739700157 0.234961136 0.964506173 0.923722538 "NPI46 -- protein folding -- Peptidylprolyl cis-trans isomerase (PPIase) of nucleolus, has FK506- and rapamycin-binding activity" YMR145C YMR145C 6.3 18 12.8 0.8921 0.724023397 iYMR145C 0.343879848 0.556272594 0.305031447 YMR145C -- unknown -- Mitochondrial NADH dehydrogenase that catalyzes cytosolic NADH oxidation YGR020C VMA7 5.6 16 12.8 0.8921 0.664334504 iYGR020C 0.247132131 0.703996133 0.23231427 VMA7 -- vacuolar acidification -- Vacuolar H(+)-ATPase (V-ATPase) 14 kDa subunit (subunit F) of catalytic (V0) sector YLR354C TAL1 5.2 15 12.8 0.8921 0.776732996 iYLR354C 0.850297572 0.953190461 0.502137614 "TAL1 -- pentose phosphate cycle -- Transaldolase, component of non-oxidative part of pentose-phosphate pathway" YNL151C RPC31 3.4 10 12.7 0.8911 1 0.32137578 iYNL151C 0.901574989 0.285412606 0.251013923 "RPC31 -- transcription -- RNA polymerase III, small subunit, essential subunit, not shared" YBR011C IPP1 12.3 36 12.7 0.8911 0.752000922 iYBR011C YBRCdelta11 0.807497759 0.811419558 0.784241789 0.914482879 0.604173381 "IPP1 -- phosphate metabolism -- Inorganic pyrophosphatase, cytoplasmic" YER178W PDA1 7.3 21 12.7 0.8911 0.862162029 iYER177W 0.480542108 0.994918125 0.421069614 PDA1 -- glycolysis -- Pyruvate dehydrogenase complex E1-alpha subunit (pyruvate YFR044C YFR044C 6.5 19 12.7 0.8911 0.508311917 iYFR044C 0.224623604 0.972977333 0.119395712 "YFR044C -- unknown -- unknown function, has similarity to Ybr281p" YJL052W TDH1 3.6 10 12.7 0.8911 0.906983029 iYJL053W 0.506704908 0.856792835 0.417037636 "TDH1 -- glycolysis -- Glyceraldehyde-3-phosphate dehydrogenase 1, converts D-glyceraldehyde 3-phosphate to 1,3-diphosphoglycerate" YDR519W FKB2 4.4 13 12.6 0.8907 0.109827774 iYDR518W 0.359476858 0.36649387 0.340289571 "FKB2 -- protein folding -- FK506-binding endoplasmic reticulum, predicted peptidylprolyl cis-trans isomerase, homolog of human FKBP13" YKR081C YKR081C 3.7 11 12.6 0.8907 0.415809302 iYKR081C 0.716013722 0.751705653 0.617587295 YKR081C -- unknown -- unknown function YDL232W OST4 5.6 17 12.5 0.8899 0.675560948 iYDL233W 0.254243276 0.408797937 0.26424581 OST4 -- protein glycosylation -- Oligosaccharyltransferase subunit of length 36 amino acids YMR123W PKR1 5.6 17 12.5 0.8899 0.413917572 iYMR122C-0 iYMR122C-1 0.377522607 0.033755916 0.432523998 0.221787709 0.177650661 PKR1 -- killer toxin sensitivity (Pichia farinosa toxin) -- unknown function YGR157W CHO2 4.9 15 12.5 0.8899 0.54589645 iYGR156W 0.82445248 0.595922677 0.913551402 "CHO2 -- phospholipid metabolism -- Phosphatidylethanolamine N-methyltransferase, carries out first methylation step in the phosphatidylcholine biosynthesis pathway" YKL172W EBP2 3.7 11 12.5 0.8899 0.332666211 iYKL173W 0.372687981 0.068874701 0.114430468 EBP2 -- unknown -- similarity to human nucleolar protein p40 YMR011W HXT2 7 21 12.4 0.8897 0.583955572 iYMR010W-0 iYMR010W-1 0.590738321 0.06596271 0.666693522 0.706413149 0.115216632 "HXT2 -- transport -- High-affinity hexose transporter, member of hexose transport family of major facilitator superfamily (MFS)" YDR210W YDR210W 6.5 20 12.3 0.8884 0.448380971 iYDR208W 0.31008941 0.86451782 0.30837938 YDR210W -- unknown -- unknown function YER012W PRE1 6.2 19 12.3 0.8884 0.817509446 iYER011W iYERWdelta7 0.781818994 0.779783626 0.922218626 0.896249002 0.807017544 PRE1 -- protein degradation -- Proteasome subunit beta4_sc (C11protease yscE subunit 11) YOR046C DBP5 4.3 13 12.3 0.8884 0.258795891 iYOR046C 0.176048988 0.688473018 0.136807292 "DBP5 -- mRNA export -- ATP-dependent cytosolic RNA helicase, required for poly(A+) RNA export" YIL094C LYS12 4 12 12.3 0.8884 0.582490897 iYIL094C 0.436703638 0.786225623 0.443658281 "LYS12 -- lysine biosynthesis -- Homoisocitrate dehydrogenase, converts homoisocitrate to alpha-ketoadipate, the fourth step in the lysine biosynthesis pathway" YPL050C MNN9 3.5 11 12.3 0.8884 0.427789715 iYPL050C 0.057921421 0.455101328 0.021575821 "MNN9 -- protein glycosylation -- complex N-glycosylation, subunit of Anp1p-Hoc1p-Mnn11p-Mnn9p mannosyltransferase complex" YNL175C YNL175C 3.1 10 12.3 0.8884 0.431072575 0.608315863 "YNL175C -- unknown -- similarity to Nsr1p, has two RNA recognition (RRM) domains" YML123C PHO84 2.2 7 12.3 0.8884 0.910383989 iYML123C 0.554130389 0.687908365 0.318240413 "PHO84 -- transport -- High-affinity inorganic phosphate/H+ symporter, member of phosphate" YDL157C YDL157C 5.7 18 12.2 0.888 0.473085979 iYDL157C 0.222632287 0.588287489 0.537270551 YDL157C -- unknown -- unknown function YBL001C ECM15 5.6 17 12.2 0.888 0.142313065 iYBL001C CEN2 0.267929416 0.675732556 0.178037687 0.162101192 0.400890689 ECM15 -- cell wall biogenesis -- Protein possibly involved in cell wall structure or biosynthesis YPL081W RPS9A 4.5 14 12.1 0.887 1 1 0.963311628 iYPL082C IntYPL081W 0.953480189 0.963957202 0.836830412 0.128651237 0.821085747 "RPS9A -- protein synthesis -- Ribosomal protein S9 (yeast S13YS11YP28rp21E. coli S4rat S9), nearly identical to Rps9Bp" YOR327C SNC2 4.4 14 12.1 0.887 0.131952308 iYOR327C 0.135793801 0.205450734 0.366563715 SNC2 -- secretion -- Synaptobrevin (v-SNARE) homolog present on post-Golgi vesicles YHL050C YHL050C 4.3 12.5 12.1 0.887 0.959311634 iYHL050C 0.923903199 0.512370311 0.712149375 "YHL050C -- unknown -- similarity to other subtelomerically-encoded proteins, putative DNA helicase" YOR184W SER1 4.2 13 12.1 0.887 0.956205586 iYOR183W 0.900399634 0.938771276 0.16603653 "SER1 -- serine biosynthesis -- 3-phosphoserine transaminase, involved in synthesis of serine from 3-phosphoglycerate" YNL153C GIM3 3.6 11 12.1 0.887 0.975068804 iYNL153C 0.811096033 0.575034941 0.112739138 "GIM3 -- protein folding -- Prefoldin subunit 4, component of Gim protein complex that promotes formation of functional alpha- and gamma-tubulin, and actin" YOL129W YOL129W 6.2 19 12 0.8864 0.291389195 iYOL130W 0.494824197 0.286549708 0.373638784 YOL129W -- unknown -- unknown function YER126C YER126C 3.4 10 12 0.8864 0.219757092 iYER126C 0.474346952 0.635856708 0.250119713 YER126C -- unknown -- Nuclear unknown function YNL075W IMP4 3.1 10 12 0.8864 0.689725501 iYNL076W 0.133168437 0.822027071 0.331124057 "IMP4 -- rRNA processing -- Component of U3 snoRNP, required for pre-18S rRNA processing" YGL106W MLC1 5.7 18 11.9 0.8852 0.33549693 iYGL107C 0.162585011 0.322591041 0.125191579 MLC1 -- cytoskeleton -- Myosin light chain YDL004W ATP16 5.5 17 11.9 0.8852 0.537649257 iYDL005C 0.14698607 0.759421702 0.44172812 ATP16 -- ATP synthesis -- Delta subunit of F1-ATP synthase YOR260W GCD1 4.7 15 11.9 0.8852 0.28011134 iYOR259C 0.287923515 0.678546471 0.410239801 "GCD1 -- protein synthesis -- Translation initiation factor eIF2B (guanine nucleotide exchange factor), 58 kDa subunit" YAL036C YAL036C 3.9 12 11.9 0.8852 0.694103167 iYAL036C 0.45051853 0.576901289 0.598130841 YAL036C -- unknown -- similarity to Xenopus laevis DRG GTP-binding protein YPL163C SVS1 3.5 11 11.9 0.8852 0.461082392 iYPL163C 0.873184532 0.421864847 0.24285013 SVS1 -- vanadate resistance -- Serine- and threonine-rich vanadate resistance YER146W LSM5 2.9 9 11.9 0.8852 0.853865831 iYER145C 0.540582037 0.906542056 0.253609744 LSM5 -- mRNA splicing (putative) -- U6 snRNA-associated Sm-like group YFL037W TUB2 6.5 20 11.8 0.884 0.429722094 iYFL038C 0.232065054 0.762840671 0.072510474 "TUB2 -- cytoskeleton -- Tubulin beta chain, required for mitosis and karyogamy" YJL167W ERG20 5.5 17 11.8 0.884 0.654551129 iYJL168C 0.362992295 0.914961014 0.330855019 "ERG20 -- sterol metabolism -- Farnesyl pyrophosphate synthetase (FPP synthetase), may be rate-limiting step in sterol biosynthesis pathway" YDR510W SMT3 5.4 17 11.8 0.884 0.265541399 iYDR509W 0.171081217 0.428731045 0.315302144 "SMT3 -- protein degradation -- Ubiquitin-related protein, homolog of human SUMO-1 protein, becomes conjugated to other proteins in a process requiring ATP, Uba2p, Aos1p, and Ubc9p" YMR226C YMR226C 5.4 17 11.8 0.884 0.383959295 iYMR226C 0.31596249 0.303738318 0.064612406 YMR226C -- unknown -- similarity to insect-type short-chain alcohol dehydrogenase YDR055W PST1 4.7 15 11.8 0.884 0.574799901 iYDR054C 0.761858507 0.446699353 0.928906443 PST1 -- unknown -- similarity to members of Sps2p-Ecm33p-Ycl048p family YER030W YER030W 4.3 13 11.8 0.884 0.685794364 iYER029C 0.486484716 0.086448598 0.033918595 YER030W -- unknown -- unknown function YIL062C ARC15 5.1 16 11.7 0.8832 0.424412369 iYIL062C 0.321136883 0.677280329 0.046539961 ARC15 -- cytoskeleton -- Component of ARP2/3 actin-organizing complexinvolved in actin assembly and function YOR361C PRT1 5.1 16 11.7 0.8832 0.596597261 iYOR361C 0.167020582 0.635594586 0.150486073 "PRT1 -- protein synthesis -- Translation initiation factor eIF3 beta subunit (p90), has an RNA recognition (RRM) domain" YOL092W YOL092W 3.8 12 11.7 0.8832 0.529137345 iYOL093W 0.282727698 0.739284563 0.210694334 YOL092W -- unknown -- unknown function YCL018W LEU2 3.3 10 11.7 0.8832 0.509250435 iYCLWdelta5 tL(CAA)C 0.720981297 0.688560526 0.881969062 0.455753551 0.641611424 "LEU2 -- leucine biosynthesis -- 3-Isopropylmalate dehydrogenase, catalyzes the third step in the leucine biosynthesis pathway" YCL043C PDI1 6.7 21 11.6 0.8822 0.805759676 0.85794347 PDI1 -- protein folding -- disulfide isomerase and oxidoreductase YIR037W HYR1 5.6 18 11.6 0.8822 0.319631801 iYIR036C 0.459906116 0.541021548 0.223386279 HYR1 -- oxidative stress response -- Glutathione peroxidase involved in oxidative stress response YKL085W MDH1 4.8 16 11.6 0.8822 0.340043563 iYKL086W 0.298575613 0.83569453 0.112897986 "MDH1 -- TCA cycle -- Malate dehydrogenase, mitochondrial" YLL008W DRS1 3.3 10 11.6 0.8822 0.309106419 iYLL009C 0.04426658 0.361968238 0.02258611 DRS1 -- rRNA processing -- RNA helicase of DEAD box family involved in rRNA biogenesis YKL209C STE6 3 10 11.6 0.8822 0.276461414 iYKL209C tT(CGU)K 0.394399308 0.664897092 0.721069433 0.48028731 0.233979255 "STE6 -- mating -- Membrane transporter responsible for export of ""a"" factor mating pheromone member of ATP-binding cassette (ABC) superfamily" YPL225W YPL225W 8 26 11.5 0.8807 0.876153473 iYPL226W 0.570060886 0.586831604 YPL225W -- unknown -- unknown function YCL019W 7 22 11.5 0.8807 0.358042964 0.644510769 YAR020C PAU7 6.1 20 11.5 0.8807 0.780022984 iYAR020C-0 iYAR020C-1 0.355097735 0.369927761 0.651788592 0.7138564 0.663708962 "PAU7 -- unknown -- Member of seripauperin (PAU) family, has strong similarity to Pau3p/Ycr104p" YKL190W CNB1 5.3 17.5 11.5 0.8807 0.466937372 iYKL191W 0.263992409 0.483502016 0.115915141 CNB1 -- signaling -- Calcineurin regulatory (B) subunit YLR294C YLR294C 5.2 17 11.5 0.8807 0.77747484 0.654735456 "YLR294C -- unknown -- unknown function, possibly involved in respiration" YIR012W SQT1 4.2 13 11.5 0.8807 0.64513199 iYIR011C 0.134793521 0.748842777 0.142615749 SQT1 -- ribosome biogenesis (putative) -- may be required for ribosomal assemblyhas WD (WD-40) repeat motifs YOR168W GLN4 3.9 13 11.5 0.8807 0.548059005 iYOR167C 0.663755581 0.661565046 0.375370679 GLN4 -- protein synthesis -- Glutaminyl-tRNA synthetase YER091C MET6 3.5 11 11.5 0.8807 0.630628294 iYER091C YER091C-A 0.613276725 0.28527004 0.848843907 0.549004193 0.125120851 "MET6 -- methionine biosynthesis -- Homocysteine methyltransferase (5-methyltetrahydropteroyl triglutamate-homocysteine methyltransferase), methionine synthase, cobalamin-independent" YEL077C 4.2 13 11.4 0.8803 0.872429982 iYEL077C 0.835749566 0.29708246 0.411793176 YJL225C YJL225C 4.2 14 11.4 0.8803 0.963671807 iYJL225C-0 iYJL225C-1 0.995603761 0.996758778 0.481326127 0.078441649 0.357542726 "YJL225C -- unknown -- near identity to other subtelomerically-encoded proteins including Yil177p, Yhr219p, and Yhl079p" YLL018C DPS1 5.5 18 11.3 0.8793 0.687881505 iYLL018C 0.370187354 0.866016758 0.725541353 "DPS1 -- protein synthesis -- Aspartyl-tRNA synthetase, cytoplasmic" YOR259C RPT4 5.5 18 11.3 0.8793 0.142747868 iYOR259C 0.287923515 0.176980387 0.410239801 RPT4 -- protein degradation -- Component of 26S proteasome complex and member of AAA family of ATPases YLR192C HCR1 4.9 16 11.3 0.8793 0.176597714 iYLR192C 0.284911585 0.282651072 0.497701057 "HCR1 -- unknown -- Putative component of translation initiation factor eIF3, has similarity to human eIF3 p35 subunit" YML008C ERG6 4.3 14 11.3 0.8793 0.394261793 iYML008C 0.303277182 0.428525016 0.365203512 "ERG6 -- sterol metabolism -- S-adenosylmethionine delta-24-sterol-C-methyltransferase, carries out methylation of zymosterol as part of ergosterol biosynthesis pathway" YKL099C YKL099C 2.9 10 11.3 0.8793 0.243639944 iYKL099C 0.538981092 0.350199521 0.727864143 YKL099C -- unknown -- unknown function YPL271W ATP15 5.4 18 11.2 0.8781 0.361821053 iYPL272C-0 iYPL272C-1 0.144273674 0.26695951 0.32291331 0.324685788 0.328911795 ATP15 -- ATP synthesis -- Epsilon subunit of F1-ATP synthaseone copy is found in each F1 oligomer YMR045C 5.1 16 11.2 0.8781 0.2021772 0.178145314 YBR162W-A YSY6 3.9 13 11.2 0.8781 0.406986212 iYBR162C 0.186916873 0.614004772 0.267295597 YSY6 -- secretion (putative) -- probable function in the secretory pathway YIL008W YIL008W 3.9 13 11.2 0.8781 0.687538128 iYIL009W 0.725769459 0.861014762 0.874681149 YIL008W -- unknown -- Ubiquitin-related protein conjugated to other proteins by Uba4p YNR043W MVD1 3.5 12 11.2 0.8781 0.271404454 iYNR042W 0.453397067 0.554595573 0.28013213 MVD1 -- sterol metabolism -- Mevalonate diphosphate (MVAPP) decarboxylase (MVA-5-pyrophosphate decarboxylase) YJL157C FAR1 2.6 9 11.2 0.8781 0.544190312 iYJL157C 0.442586664 0.898723065 0.527134876 FAR1 -- cell cycle -- Inhibitor of Cdc28p-Cln1p and Cdc28p-Cln2p kinase complexes involved in cell cycle arrest for mating YOR355W GDS1 2.9 10 11.1 0.8769 1 0.571358977 iYOR354C-0 iYOR354C-1 0.925420027 0.965657265 0.519094289 0.610055866 0.242568228 "GDS1 -- respiration (putative) -- suppresses nam9-1 glycerol deficient phenotype when overexpressed, involved in nuclear control of mitochondria" YOR332W VMA4 6.4 21 11.1 0.8769 0.298152965 0.199772886 "VMA4 -- vacuolar acidification -- Vacuolar H(+)-ATPase (V-ATPase) hydrophilic subunit (subunit E), 27 kDa subunit of V1 sector" YKL196C YKT6 4.5 15 11.1 0.8769 0.720705152 iYKL196C 0.301026728 0.857267645 0.475308642 "YKT6 -- secretion -- Synaptobrevin (v-SNARE) homolog with similarity to Sec22p, Snc1p, and Snc2p, essential for endoplasmic reticulum-Golgi transport" YLR074C YLR074C 3.7 12 11.1 0.8769 0.95406189 iYLR074C 0.965446025 0.752355426 0.430309378 "YLR074C -- unknown -- unknown function, has a single C2H2-type zinc finger" YDR321W ASP1 3.1 10 11.1 0.8769 0.673529231 iYDR320C 0.29164636 0.875750843 0.539793849 "ASP1 -- asparagine utilization -- Asparaginase, (L-asparagine aminohydrolase I), intracellular isozyme that converts asparagine to aspartate and ammonia" YNR067C YNR067C 2.8 9 11.1 0.8769 0.763269944 iYNR067C 0.714942969 0.697287199 0.821585605 "YNR067C -- unknown -- similarity to C. albicans Eng1p, endo-1,3-beta-glucanase" YCL036W YCL036W 2.9 10 11 0.8755 1 0.977096742 iYCL037C 0.960346205 0.320662768 0.151642208 YCL036W -- unknown -- unknown function YDR071C YDR071C 6.1 20 11 0.8755 0.570320637 iYDR071C 0.528921528 0.736439359 0.553359684 YDR071C -- unknown -- unknown function YML052W SUR7 4 13 11 0.8755 0.698119761 iYML053C 0.505701537 0.596031298 0.506900769 SUR7 -- endocytosis (putative) -- unknown functionoverproduction suppresses the rvs167 mutation YNL149C YNL149C 4 14 11 0.8755 0.925008723 iYNL149C 0.441711143 0.192872117 0.111397919 YNL149C -- unknown -- unknown function YGL256W ADH4 3.9 13 11 0.8755 0.722133394 iYGL257C 0.185512606 0.850151563 0.074541101 ADH4 -- glycolysis -- Alcohol dehydrogenase IV YKR013W PRY2 3.4 11 11 0.8755 0.252456996 0.351214003 PRY2 -- unknown -- expressed under starvation conditions YNL015W PBI2 3.3 11 11 0.8755 0.324761144 iYNL016W 0.609046615 0.21109946 0.593129415 "PBI2 -- unknown -- Protease B (yscB or Prb1p) inhibitor 2 (I2B), has activity related to vacuolar fusion that is not related to protease activity" YOR010C TIR2 5.1 17 10.9 0.8747 0.343161105 iYOR010C-0 iYOR010C-1 0.234709768 0.457545768 0.37309902 0.193614745 0.610308946 "TIR2 -- unknown -- Cold-shock induced protein, member of seripauperin (PAU) family" YIL076W SEC28 4.9 17 10.9 0.8747 0.361282832 iYIL077C 0.267643764 0.72337838 0.70207502 SEC28 -- secretion -- Coatomer (COPI) complex epsilon chain (epsilon-COP) of secretory pathway vesiclesrequired for retrograde transport from Golgi to endoplasmic reticulum YER049W YER049W 3.6 12 10.9 0.8747 0.386184774 iYER048W-A YER048W-A 0.746795843 0.586645929 0.625359993 0.845688009 0.856912665 YER049W -- unknown -- unknown function YIL015W BAR1 2 7 10.9 0.8747 0.507089312 iYIL016W 0.733502123 0.866959064 0.909322801 BAR1 -- mating -- Secreted pepsin-like protease that degrades alpha-factor YCL011C GBP2 7.2 25 10.8 0.8739 0.248951068 iYCL011C 0.605731727 0.25450506 0.600988574 "GBP2 -- unknown -- Potential telomere-associated binds single-stranded G-strand telomere sequence, has three RNA recognition (RRM) domains" YCR028C-A RIM1 5.3 18.5 10.8 0.8739 0.600254993 iYCR028C-A 0.459294806 0.664405427 0.687470072 "RIM1 -- mitochondrial DNA maintenance -- binds single-stranded DNA, required for replication in mitochondria, has three C2H2-type zinc fingers" YLL014W YLL014W 4.8 17 10.8 0.8739 0.599959039 iYLL015W 0.582843863 0.818069612 0.453996133 YLL014W -- unknown -- unknown function YML125C YML125C 3.8 13 10.8 0.8739 0.7414408 iYML125C 0.348495917 0.883074138 0.134452399 YML125C -- unknown -- similarity to NADH-cytochrome b5 reductase YGL187C COX4 4.9 17 10.7 0.8726 0.987116684 iYGL187C 0.89576702 0.992023848 0.680211139 COX4 -- oxidative phosphorylation -- Cytochrome-c oxidase subunit IV YDL067C COX9 4.8 17 10.7 0.8726 0.289090763 iYDL067C 0.331189849 0.191427651 0.31007097 "COX9 -- oxidative phosphorylation -- Cytochrome-c oxidase subunit VIIA, essential component of cytochrome-c holoenzyme" YJL001W PRE3 4.5 16 10.7 0.8726 0.425308383 iYJL002C 0.485607212 0.465921788 0.814814815 PRE3 -- protein degradation -- Proteasome subunit beta1_sc involved in peptidyl-glutamyl peptide hydrolytic activity of proteasome YDR035W ARO3 4.4 15 10.7 0.8726 0.529674434 iYDR034W-B YDR034W-B 0.412770992 0.573438379 0.384346611 0.346698113 0.389542378 ARO3 -- aromatic amino acid biosynthesis -- 2-Dehydro-3-deoxyphosphoheptonate aldolase (DAHPS)phenylalanine-inhibited YNR050C LYS9 3.7 13 10.7 0.8726 0.360743217 iYNR050C 0.708368838 0.843553459 0.392657622 "LYS9 -- lysine biosynthesis -- Saccharopine dehydrogenase (saccharopine reductaseNADP+, L-glutamate forming), seventh step in lysine biosynthesis pathway" YMR049C YMR049C 3 11 10.7 0.8726 0.237875628 iYMR049C-0 iYMR049C-1 0.415694056 0.30648017 0.440383081 0.594821328 0.506541595 "YMR049C -- unknown -- similarity to mouse Bop1 growth supressor, has one WD (WD-40) domain" YGR260W TNA1 2.5 9 10.7 0.8726 0.62478269 0.569653583 TNA1 -- unknown -- similarity to Dal5p and member of allantoate permease family of major facilitator superfamily (MFS) YLR208W SEC13 5.3 18 10.6 0.8714 0.604781816 iYLR207W 0.295414274 0.55994152 0.196181142 "SEC13 -- secretion -- Component of COPII coat of vesicles involved in endoplasmic reticulum to Golgi transport, contains six WD (WD-40) repeats" YJL055W YJL055W 5.2 18 10.6 0.8714 0.246813347 iYJL056C 0.739039973 0.163148566 0.221892746 YJL055W -- unknown -- unknown function YLR027C AAT2 5.2 18 10.6 0.8714 0.748005466 iYLR027C 0.559631037 0.937464001 0.479968077 "AAT2 -- aspartate metabolism -- Aspartate aminotransferase (2-oxoglutarate aminotransferase), cytosolic and peroxisomal" YDR483W KRE2 5.1 18 10.6 0.8714 0.775946488 iYDR482C 0.079084345 0.941181165 0.118433774 "KRE2 -- protein glycosylation -- Alpha-1,2-mannosyltransferase of KRE2 family, acts in the Golgi to add the third mannose onto O-linked carbohydrate chains" YLR295C ATP14 4.7 16 10.6 0.8714 0.755095305 iYLR295C 0.419459284 0.46269739 0.753229655 ATP14 -- ATP synthesis -- Subunit h of ATP synthase YHR092C HXT4 3.1 11 10.6 0.8714 0.57521077 iYHR092C 0.425806929 0.304267161 0.644254475 "HXT4 -- transport -- Moderate- to low-affinity hexose transporter, member of hexose transporter family of major facilitator superfamily (MFS)" YOR375C GDH1 7.7 27 10.5 0.8704 0.33168529 iYOR375C 0.446154014 0.371428571 0.503333965 "GDH1 -- glutamate biosynthesis -- Glutamate dehydrogenase (NADP+), combines ammonia and alpha-ketoglutarate to form glutamate" YDL185W VMA1 7.4 26 10.5 0.8704 0.75691766 iYDL186W 0.896502193 0.558733484 0.24450828 "VMA1 -- vacuolar acidification -- Catalytic subunit (subunit A) of vacuolar H(+) ATPase V1 complex, generated upon protein splicing of full-length unspliced precursor protein by ligation of N-terminal and C-terminal exein moieties" YPL246C YPL246C 3.9 14 10.5 0.8704 0.128595079 iYPL246C 0.078829945 0.169193935 0.045503168 YPL246C -- unknown -- unknown function YHL003C LAG1 2.9 10 10.5 0.8704 0.840849776 iYHL003C 0.395280012 0.969787303 0.335804061 "LAG1 -- aging -- Protein required with Lac1p for ER-to-Golgi transport of GPI-anchored proteins, has indirect effect on cell longevity" YDR101C YDR101C 2.7 9 10.5 0.8704 0.668730655 iYDR101C 0.371276441 0.858282307 0.353633944 YDR101C -- unknown -- unknown function YPL237W SUI3 5.8 21 10.4 0.8688 0.321662315 0.361517219 SUI3 -- protein synthesis -- Translation initiation factor eIF2beta subunit YNL322C KRE1 5.6 20 10.4 0.8688 0.404804028 iYNL322C 0.25315304 0.666779317 0.230145319 "KRE1 -- cell wall biogenesis -- Cell wall protein needed for cell wall beta-1,6-glucan assembly, probably involved in side-chain addition to form mature beta-1,6-glucan" YOR136W IDH2 5.6 20 10.4 0.8688 0.638502058 0.912639405 "IDH2 -- TCA cycle -- Isocitrate dehydrogenase (NAD+) subunit 2, mitochondrial, required for oxidative function of tricarboxylic acid cycle" YAL042W YAL042W 3.9 14 10.4 0.8688 0.613623447 0.706023959 "YAL042W -- unknown -- unknown function, has 2 potential transmembrane segments" YDR492W 3.7 13 10.4 0.8688 0.39153106 0.426177175 YOL151W GRE2 3.6 13 10.4 0.8688 0.168866672 iYOL152W 0.447398104 0.769273743 0.059367178 GRE2 -- unknown -- diamide tolerance and induced by osmotic stress YLR083C EMP70 3.1 11 10.4 0.8688 0.31986471 iYLR083C 0.765404191 0.690708252 0.677570093 EMP70 -- secretion (putative) -- Endosomal membrane similarity to human putative ion transporter EMP70 YMR012W CLU1 3.1 11 10.4 0.8688 0.612309417 iYMR011W YMRCtau1 0.294584755 0.508449161 0.324236517 0.186671987 0.586564091 "CLU1 -- protein synthesis -- Translation initiation factor eIF3, p135 subunit" YJR007W SUI2 3.7 13 10.3 0.868 0.386757326 iYJR006W 0.546737482 0.801596169 0.766728625 SUI2 -- protein synthesis -- Translation initiation factor eIF2alpha subunit YGR162W TIF4631 3.4 12 10.3 0.868 0.404650734 iYGRCdelta30 itV(AAC)G2 0.458437891 0.239094299 0.491146849 0.654612159 0.162473795 TIF4631 -- protein synthesis -- mRNA cap-binding protein (eIF4F) 150K subunit YJL173C RFA3 3.3 12 10.3 0.868 0.609494033 iYJL173C 0.367959432 0.626651627 0.4896249 "RFA3 -- DNA replication -- DNA replication factor A, 13K subunit" YGR200C ELP2 2.8 10 10.3 0.868 0.405684034 iYGR200C 0.519385645 0.726393812 0.296326136 "ELP2 -- unknown -- 90 kDa subunit of elongator and elongating RNA polymerase II holoenzyme, has WD (WD-40) repeats" YFL031W HAC1 4 15 10.2 0.8668 0.662988164 0.735266316 "HAC1 -- unfolded protein response -- Transcription factor that activates the unfolded protein response (UPR) pathway, regulated mRNA splicing is initiated by Ire1p, and only the product of spliced mRNA is able to induce the response" YDL095W PMT1 3.9 14 10.2 0.8668 0.482385582 0.642645003 PMT1 -- protein glycosylation -- Mannosyltransferase (dolichyl phosphate-D-mannose YDL078C MDH3 3.3 12 10.2 0.8668 0.346240289 iYDL078C 0.256181634 0.300913355 0.339751502 "MDH3 -- TCA cycle -- Malate dehydrogenase, peroxisomal" YOR342C YOR342C 2.5 9 10.2 0.8668 0.70603893 iYOR342C 0.913426985 0.453053931 0.32580463 YOR342C -- unknown -- unknown function YDL060W YDL060W 2.4 8 10.2 0.8668 0.67000609 iYDL061C 0.989542094 0.247194493 0.337988827 YDL060W -- unknown -- unknown function YGR187C HGH1 2.2 8 10.2 0.8668 0.236848607 iYGR187C 0.430382205 0.334384752 0.488644305 HGH1 -- unknown -- similarity to human HMG1 and HMG2 proteins YNL070W TOM7 5.2 19 10.1 0.8656 0.541120669 iYNL071W 0.551724138 0.622233193 0.301040574 TOM7 -- mitochondrial protein targeting -- Small subunit of translocase involved in mitochondrial protein import YPL094C SEC62 3.6 13 10.1 0.8656 0.853980053 iYPL094C 0.673786755 0.134205546 0.626676541 "SEC62 -- secretion -- Component of ER protein-translocation subcomplex which includes Sec62p, Sec63p, Sec66p, and Sec72p" YER072W NRF1 3.1 11 10.1 0.8656 0.828152125 iYER071C 0.563065542 0.62962963 0.768437297 "NRF1 -- signaling, polarized growth (putative) -- the distribution of V-ATPase and other membrane proteins" YGL120C PRP43 2.9 11 10.1 0.8656 0.600063892 iYGL120C 0.557116181 0.792530451 0.514587701 "PRP43 -- mRNA splicing -- Pre-mRNA splicing factor, member of DEAH-box RNA helicase family" YDL219W YDL219W 2.8 10 10.1 0.8656 0.366332317 iYDL220C 0.658118106 0.680572698 0.720577559 YDL219W -- unknown -- D-Tyr-tRNA[Tyr] deacylase YPL012W YPL012W 2.2 8 10.1 0.8656 0.462927877 iYPL013C 0.148858047 0.363687151 0.119787045 YPL012W -- unknown -- unknown function YFL022C FRS2 3.8 14 10 0.8643 1 0.848191633 iYFL022C 0.990286547 0.53506847 0.286136432 "FRS2 -- protein synthesis -- Phenylalanyl-tRNA synthetase, beta subunit, cytoplasmic" YJL166W QCR8 5.6 21 10 0.8643 0.581384586 iYJL167W 0.379848948 0.724930119 0.4632083 QCR8 -- oxidative phosphorylation -- Ubiquinol cytochrome-c reductase subunit 8 (11 kDa protein)component of ubiquinol cytochrome-c reductase complex (cytochrome bc1 complex) YEL001C YEL001C 3.5 13 10 0.8643 0.443902808 iYEL001C CEN5 0.488654179 0.770569932 0.735867446 0.516711158 0.280460296 YEL001C -- unknown -- unknown function YER007C-A 3.3 12 10 0.8643 0.229416482 iYER007C-A snR14 0.848138918 0.74363914 0.604332445 0.962962963 0.564387394 YDR144C MKC7 3.1 12 10 0.8643 0.195761769 iYDR144C 0.510090063 0.138736706 0.633203379 "MKC7 -- protein degradation -- Aspartyl protease found in the periplasmic space, has similarity to Yps1p and Bar1p" YLR196W PWP1 3.1 12 10 0.8643 0.103412235 iYLR195C 0.432717076 0.168635275 0.36054256 "PWP1 -- unknown -- Periodic tryptophan protein, has WD (WD-40) repeats" YJR048W CYC1 2.6 10 10 0.8643 0.588642197 iYJR047C 0.66482383 0.744776962 0.180127694 "CYC1 -- oxidative phosphorylation -- Cytochrome-c isoform 1, predominant isoform during aerobic growth" YBR111C YSA1 5.1 19 9.9 0.8625 0.582900602 iYBR111C 0.503001711 0.877860135 0.542568352 YSA1 -- unknown -- Nucleoside diphosphate-sugar hydrolase of MutT (nudix) family YJR121W ATP2 4.3 16 9.9 0.8625 0.763337379 iYJR120W 0.609403696 0.751955307 0.371817596 "ATP2 -- ATP synthesis -- Beta subunit of F1-ATP synthase, three copies are present in each F1 complex" YDL124W YDL124W 3.7 14 9.9 0.8625 0.635187136 iYDL125C 0.512831092 0.776340509 0.809901994 YDL124W -- unknown -- unknown function YOL143C RIB4 3.6 13 9.9 0.8625 0.57473842 iYOL143C 0.072553962 0.805840123 0.307493748 "RIB4 -- riboflavin biosynthesis -- Riboflavin biosynthesis pathway enzyme, 6,7-dimethyl-8-ribityllumazine synthase" YGR105W VMA21 3.5 13 9.9 0.8625 0.80890953 iYGR104C 0.261918161 0.909514316 0.330977908 VMA21 -- vacuolar acidification -- vacuolar H(+)-ATPase (V-ATPase) assembly YLR449W FPR4 3.5 13 9.9 0.8625 0.103053501 iYLR448W 0.826317134 0.042866378 0.936718486 FPR4 -- protein folding (putative) -- Nucleolar peptidylprolyl cis-trans isomerase (PPIase) YKL191W DPH2 3.4 13 9.9 0.8625 0.42917633 iYKL192C 0.338008263 0.785873903 0.683240223 "DPH2 -- diphthamide biosynthesis -- Diptheria toxin resistance protein, required for diphthamide biosynthesis" YDL039C YDL039C 3.1 12 9.9 0.8625 0.041493587 0.073880116 YDL039C -- unknown -- unknown function YOL124C YOL124C 3.1 12 9.9 0.8625 0.37725338 iYOL124C 0.531809555 0.702729045 0.876695164 YOL124C -- unknown -- unknown function YNL010W YNL010W 3.3 12 9.8 0.8607 1 0.943292522 iYNL011C 0.967623943 0.894813261 0.422117996 YNL010W -- unknown -- unknown function YBR127C VMA2 5.8 22 9.8 0.8607 0.604854631 iYBR127C 0.723097865 0.791804469 0.628988076 "VMA2 -- vacuolar acidification -- Vacuolar H(+)-ATPase (V-ATPase) regulatory subunit (subunit B) involved in nucleotide binding, 58 kDa subunit of V1 ATP-hydrolysis domain" YDR039C ENA2 4.9 19 9.8 0.8607 0.356153748 iYDR039C 0.702074356 0.482699805 0.92345387 ENA2 -- transport -- P-type ATPase involved in Na+ efflux YDR190C RVB1 4.4 16 9.8 0.8607 0.751940595 iYDR190C 0.589241448 0.918038822 0.440302144 RVB1 -- unknown -- Putative 3' to 5' DNA/RNA helicase involved in ribosomal RNA processing YOR232W MGE1 3.6 14 9.8 0.8607 0.419968814 iYOR231W 0.467311879 0.631335283 0.673622301 "MGE1 -- mitochondrial protein targeting -- Homolog of E. coli GrpE, participates with Ssc1p and Mdj1p in folding of proteins during mitochondrial import" YNL098C RAS2 3.5 13 9.8 0.8607 0.755827829 iYNL098C 0.214949158 0.873195128 0.408077053 "RAS2 -- signaling, Ras pathway -- GTP-binding regulation of cAMP pathway, homolog of mammalian proto-oncogene ras" YJL217W YJL217W 3 11 9.8 0.8607 0.545447034 iYJL218W 0.4276005 0.788416552 0.729450674 YJL217W -- unknown -- unknown function YOR078W YOR078W 2.5 9 9.8 0.8607 0.058993908 iYOR077W 0.168917408 0.104253948 0.112365895 YOR078W -- unknown -- unknown function YCR087C-A 2.1 8 9.8 0.8607 YBR283C SSH1 5.1 19 9.7 0.8601 0.349952577 iYBR283C 0.371552176 0.562330289 0.38531514 "SSH1 -- secretion -- Component of Ssh1p-Sss1p-Sbh2p complex, involved in protein translocation into the endoplasmic reticulum" YJL151C YJL151C 3.4 13 9.7 0.8601 0.679637252 iYJL151C 0.125789218 0.734777484 0.060734238 YJL151C -- unknown -- unknown function YOR246C YOR246C 3.3 13 9.7 0.8601 0.126541152 iYOR246C 0.583827231 0.407494759 0.433390932 YOR246C -- unknown -- unknown function YLR100W ERG27 3.9 15 9.6 0.8589 0.48895891 iYLR099C 0.308696027 0.534929647 0.39896874 "ERG27 -- unknown -- 3-Keto sterol reductase, required for ergosterol biosynthesis" YMR120C ADE17 3.7 14 9.6 0.8589 0.347054782 iYMR120C 0.454936183 0.403933185 0.682423167 ADE17 -- purine biosynthesis -- 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR) transformylase/IMP cyclohydrolase YHR045W YHR045W 3.4 13 9.6 0.8589 0.432953586 iYHR044C 0.550011383 0.682261838 0.772283617 "YHR045W -- unknown -- unknown function, has 5 potential transmembrane domains" YDL131W LYS21 3 12 9.6 0.8589 0.946360201 iYDL132W 0.475607111 0.988545616 0.36480825 "LYS21 -- lysine biosynthesis -- Homocitrate synthase isoenzyme, involved in lysine metabolism" YDR465C RMT2 2.7 10 9.6 0.8589 0.337371356 iYDR465C 0.342592912 0.590891567 0.360569407 RMT2 -- arginine metabolism -- Putative protein arginine methyltransferasehas similarity to human guanidinoacetate N-methyltransferase YAL025C MAK16 2.5 10 9.6 0.8589 0.121989157 iYAL025C 0.444424237 0.260883691 0.362749052 "MAK16 -- dsRNA virus propagation -- Nuclear HMG-like acidic region, required for propagation of M1 double-stranded RNA" YDR011W SNQ2 6.3 24 9.5 0.8573 0.615507075 iYDR010C 0.470414755 0.384280215 0.444828437 "SNQ2 -- 4-nitroquinoline-N-oxide resistance -- Drug-efflux pump involved in resistance to multiple drugs, member of ATP-binding cassette (ABC) superfamily" YDL100C YDL100C 6.1 23 9.5 0.8573 0.295762255 iYDL100C 0.119276172 0.503752357 0.140788283 YDL100C -- unknown -- similarity to E. coli ArsA ATPase component of arsenite-antimonite efflux pump YKR043C YKR043C 4.5 17 9.5 0.8573 0.162751267 iYKR043C 0.144533921 0.089831059 0.313088587 YKR043C -- unknown -- similarity to phosphoglycerate mutase YLL009C COX17 4.2 16 9.5 0.8573 0.452154193 iYLL009C 0.04426658 0.241429378 0.02258611 COX17 -- respiration -- Cytoplasmic proteininvolved in delivery of copper ions to mitochondrial cytochrome oxidase YIL011W YIL011W 3.9 15 9.5 0.8573 0.34995186 iYIL012W 0.29080083 0.176007147 0.252703616 YIL011W -- unknown -- Member of seripauperin (PAU) family of possible cell wall mannoproteins YGR229C SMI1 3.3 13 9.5 0.8573 0.207931195 iYGR229C 0.484844066 0.257940942 0.841374269 "SMI1 -- cell wall biogenesis -- beta-1,3-glucan synthesis, possibly through regulation of cell wall glucan and chitin synthesis" YNL232W CSL4 3.1 12 9.5 0.8573 0.55591688 iYNL233W 0.206193122 0.385397896 0.184118117 "CSL4 -- mitosis, chromosome segregation -- member of both the cytoplasmic and nucleolar forms of exosome 3'->5' exonuclease complex, possibly involved in kinetochore-related function" YKL122C SRP21 3 12 9.5 0.8573 0.510659395 iYKL122C 0.338214021 0.285988819 0.468305814 SRP21 -- secretion -- Signal recognition particle subunitno homologous subunit yet detectable in mammals YCL030C HIS4 5.1 20 9.4 0.856 1 0.917384174 iYCL030C 0.974354786 0.660482375 0.323788013 "HIS4 -- histidine biosynthesis -- Phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphohydrolase / histidinol dehydrogenase, second, third, and tenth steps of histidine biosynthesis pathway" YGL026C TRP5 5.7 23 9.4 0.856 0.861885584 iYGL026C 0.546243906 0.971872816 0.405426975 "TRP5 -- tryptophan biosynthesis -- Tryptophan synthase, last (fifth) step in tryptophan biosynthesis pathway" YPL078C ATP4 5.3 21 9.4 0.856 0.449211788 iYPL078C 0.418490689 0.301605227 0.206914869 "ATP4 -- ATP synthesis -- Subunit 4 of F0-ATP synthase, has similarity to bovine subunit b" YGR151C YGR151C 3.4 13.5 9.4 0.856 0.784548597 0.633939239 YGR151C -- unknown -- unknown function YML105C SEC65 3.1 12 9.4 0.856 0.266579549 iYML105C 0.765736796 0.508242442 0.685756603 SEC65 -- secretion -- Signal recognition particle subunit SRP19 YEL003W GIM4 3 12 9.4 0.856 0.7194249 iYEL004W 0.269788714 0.636797499 0.561633903 "GIM4 -- protein folding -- Prefoldin subunit 2, component of Gim protein complex that promotes formation of functional alpha- and gamma-tubulin, and actin" YBL042C FUI1 2.5 10 9.4 0.856 0.438605645 iYBL042C 0.376613043 0.806138402 0.326939411 "FUI1 -- transport -- Uridine permease, member of uracil/allantoin family of membrane transporters" YGL202W ARO8 5.4 21 9.3 0.855 0.46876493 iYGL203C iYGLWdelta3 0.530542452 0.772277815 0.938307713 0.469054581 0.78371768 ARO8 -- aromatic amino acid biosynthesis -- Aromatic amino acid aminotransferase I YBR034C HMT1 3.4 14 9.3 0.855 0.770927128 iYBR034C 0.573473467 0.862552369 0.392166543 HMT1 -- protein processing -- arginine methyltransferase YNL308C KRI1 3.4 13 9.3 0.855 0.576013121 iYNL308C 0.332670435 0.816012507 0.238644305 "KRI1 -- unknown -- unknown function, binds Krr1p and has weak similarity to Mgm1p" YOR265W RBL2 2.7 11 9.3 0.855 0.296496066 iYOR264W 0.727232234 0.155333548 0.558180367 RBL2 -- cytoskeleton -- rescues excess beta-tubulin lethality YCR047C YCR047C 2.4 9 9.3 0.855 0.177189574 iYCR047C 0.592784333 0.325617284 YCR047C -- unknown -- similarity to rat methylglycine transferase YNL281W HCH1 5.7 23 9.2 0.8524 0.329388662 iYNL282W 0.320680233 0.343973359 0.276234568 HCH1 -- stress response (putative) -- unknown function YDR388W RVS167 4.5 18 9.2 0.8524 0.824587924 iYDR387C 0.849569531 0.986397432 0.587576539 "RVS167 -- cytoskeleton -- affects actin distribution and bipolar budding, has an SH3 domain" YPL154C PEP4 4.4 18 9.2 0.8524 0.399578576 iYPL154C 0.080947273 0.757781325 0.556167016 PEP4 -- protein degradation -- Proteinase A (PrA/yscA/saccharopepsin)aspartyl protease required for activation of various degradative enzymes YER133W GLC7 4.2 17.5 9.2 0.8524 0.521606264 iYER132C SNR52 0.406371807 0.740996484 0.902395741 0.156257714 0.489066241 "GLC7 -- glycogen metabolism -- Protein serine/threonine phosphatase PP1 required for glucose repression, membrane bilayer mixing, and ER-to-Golgi and endocytic vesicular trafficking" YGR204W ADE3 3.9 16 9.2 0.8524 0.687318422 iYGR203W 0.763014378 0.862649641 0.47608874 "ADE3 -- purine biosynthesis -- C1-tetrahydrofolate synthase (trifunctional enzyme), cytoplasmic" YGR063C SPT4 3.8 15 9.2 0.8524 0.102573652 0.114604948 "SPT4 -- transcription -- chromatin structure that influences expression of many genes, has a zinc finger" YPL091W GLR1 3.8 15 9.2 0.8524 0.550115593 iYPL092W 0.721019085 0.458818835 0.828355139 "GLR1 -- glutathione metabolism -- Glutathione reductase, converts oxidized glutathionine + NADPH into 2 glutathionine + NADP+" YLR244C MAP1 3.7 15 9.2 0.8524 0.526298595 iYLR244C 0.424237951 0.767040413 0.392120529 "MAP1 -- protein processing -- Methionine aminopeptidase isoform 1, cleaves N-terminal methionine if next residue is small (gly, pro, ser, thr, val) and not if next residue is charged or bulky (arg, his, tyr, met, leu)" YER159C BUR6 3.1 12 9.2 0.8524 0.152504221 iYER159C 0.232038479 0.008539505 0.007211097 BUR6 -- transcription -- Alpha subunit of NC2 (Dr1/Drap1) repressor of class II transcription YBL006C YBL006C 3 12 9.2 0.8524 0.54412 iYBL006C 0.502100337 0.778183886 0.662299092 YBL006C -- unknown -- unknown function YDR496C YDR496C 2.9 12 9.2 0.8524 0.772132757 iYDR496C 0.433755145 0.4540767 0.04363959 YDR496C -- unknown -- unknown function YGL126W SCS3 2.4 9 9.2 0.8524 0.529247048 iYGL127C 0.459000327 0.43256809 0.198759265 SCS3 -- phospholipid metabolism -- inositol phospholipid biosynthesis YGR280C YGR280C 1.9 8 9.2 0.8524 0.100709934 iYGR280C 0.357014334 0.030965682 0.262465817 YGR280C -- unknown -- unknown function YBR086C IST2 4.4 18 9.1 0.8506 0.344052701 iYBR086C 0.643744418 0.570460595 0.630765808 "IST2 -- salt tolerance (putative) -- Putative ion channel protein, has a role in sensitivity to NaCl" YGL048C RPT6 4.4 18 9.1 0.8506 0.722923749 iYGL048C 0.190391532 0.800185874 0.129449322 "RPT6 -- protein degradation -- ATPase component of 26S proteasome complex, member of AAA family of ATPases" YPR069C SPE3 3.6 15 9.1 0.8506 0.672576688 iYPR069C 0.767032144 0.541737073 0.799266247 "SPE3 -- polyamine biosynthesis -- Putrescine aminopropyltransferase, spermidine synthase" YMR296C LCB1 3.4 14 9.1 0.8506 0.776881675 iYMR296C 0.494539373 0.852544971 0.310510071 "LCB1 -- sphinogolipid metabolism -- Component of serine C-palmitoyltransferase, first step in biosynthesis of long-chain base component of sphingolipids" YDR398W YDR398W 2.7 11 9.1 0.8506 0.23087093 iYDR397C 0.123579382 0.457253319 0.116959064 YDR398W -- unknown -- unknown function YGR090W YGR090W 2.6 11 9.1 0.8506 0.482147636 iYGR089W-0 iYGR089W-1 0.043605756 0.449542041 0.782880387 0.148749022 0.86258537 YGR090W -- unknown -- unknown function YHR052W YHR052W 2.5 10 9.1 0.8506 0.520518467 iYHR051W 0.684007507 0.91015206 0.557302586 YHR052W -- unknown -- unknown function YLR129W DIP2 2.4 10 9.1 0.8506 0.46475774 iYLR128W 0.558213735 0.691105382 0.637589785 "DIP2 -- unknown -- Dom34p-interacting protein, has WD (WD-40) repeats" YNL111C CYB5 2 8 9.1 0.8506 0.335931283 iYNL111C 0.125964114 0.370854933 0.069061367 CYB5 -- lipid metabolism -- Cytochrome b5 YBR039W ATP3 5.3 22 9 0.8485 0.766773833 iYBR038W 0.505064353 0.959699041 0.537974163 ATP3 -- ATP synthesis -- Gamma subunit of F1-ATP synthase YAR015W ADE1 4.3 18 9 0.8485 0.512548739 iYAR014C 0.312322622 0.660493827 0.326519916 "ADE1 -- purine biosynthesis -- Phosphoribosylamidoimidazole-succinocarboxamide synthase (SAICAR synthetase), catalyzes the seventh step in de novo purine biosynthesis pathway" YGL221C NIF3 4.2 17 9 0.8485 0.225433058 iYGL221C 0.343419139 0.524820431 0.119803988 NIF3 -- unknown -- Ngg1p-interaction factor YBR054W YRO2 3.8 16 9 0.8485 0.636649828 iYBR053C-0 iYBR053C-1 0.346370596 0.570428566 0.726343359 0.840799227 0.921548284 "YRO2 -- unknown -- Protein paralog of Mrh1p, has similarity to heat shock protein Hsp30" YKL160W YKL160W 3.8 16 9 0.8485 0.14077518 iYKL161C-0 iYKL161C-1 0.228181122 0.338853606 0.042018171 0.44507529 0.15266608 YKL160W -- unknown -- unknown function YDL122W UBP1 3.5 14 9 0.8485 0.456847102 iYDL123W 0.14650471 0.610728647 0.364362346 "UBP1 -- protein degradation, ubiquitin-mediated -- Ubiquitin-specific protease (ubiquitin C-terminal hydrolase), cleaves at the C-terminus of ubiquitin" YLR017W MEU1 2.9 12 9 0.8485 0.749367325 iYLR016C 0.436914802 0.982092442 0.448410347 MEU1 -- glucose derepression -- regulates ADH2 gene expression YOR283W YOR283W 2.9 12 9 0.8485 0.067002779 iYOR282W 0.424200613 0.22002924 0.379632614 YOR283W -- unknown -- similarity to phosphoglycerate mutases YOR206W YOR206W 2.7 11 9 0.8485 0.634268251 iYOR205C 0.276502633 0.555171563 0.197228489 YOR206W -- unknown -- unknown function YJR025C BNA1 2.1 9 9 0.8485 0.43891749 iYJR025C 0.349773688 0.80695318 0.175526337 "BNA1 -- nicotinic acid biosynthesis -- 3-hydroxyanthranilate 3,4-dioxygenase, involved in biosynthesis of nicotinic acid from tryptophan" YJL122W YJL122W 2 8 9 0.8485 0.599967622 iYJL123C 0.111162923 0.540273024 0.025086715 YJL122W -- unknown -- unknown function YNL208W YNL208W 6.5 27 8.9 0.8471 0.802881754 iYNL209W 0.85354507 0.818007955 0.512102014 YNL208W -- unknown -- unknown function YOR362C PRE10 5.8 24 8.9 0.8471 0.122740596 iYOR362C 0.127657966 0.095291301 0.239425379 PRE10 -- protein degradation -- Proteasome subunit alpha7_sc (YC1protease yscE subunit 1) YML092C PRE8 5.3 22 8.9 0.8471 0.665128703 iYML092C 0.417060575 0.442173305 PRE8 -- protein degradation -- Proteasome subunit alpha2_sc (protease yscE subunit Y7) YLR301W YLR301W 4.8 20 8.9 0.8471 0.714175256 iYLR300W 0.663158754 0.962330407 0.427466469 YLR301W -- unknown -- unknown function YBR069C VAP1 4.4 18 8.9 0.8471 0.732009235 iYBR069C 0.736831473 0.764217149 0.924830809 "VAP1 -- transport -- Amino acid permease that transports valine, leucine, isoleucine, tyrosine, and tryptophan" YKL080W VMA5 4 17 8.9 0.8471 0.659727354 iYKL081W 0.473513965 0.906428975 0.277709208 "VMA5 -- vacuolar acidification -- Vacuolar H(+)-ATPase (V-ATPase) hydrophilic subunit (subunit C), 42 kDa subunit of V1 sector" YPL093W NOG1 2.7 11 8.9 0.8471 0.743488016 iYPL094C 0.673786755 0.711785109 0.626676541 "NOG1 -- unknown -- Putative nucleolar G-protein, has similarity to Halobacterium cutirubrum GTP-binding protein (SP" YGL161C YGL161C 5.4 23 8.8 0.8463 0.25481355 iYGL161C 0.463002287 0.74537037 0.450999753 YGL161C -- unknown -- unknown function YIL040W YIL040W 3.5 15 8.8 0.8463 0.65541525 iYIL041W 0.715654537 0.884502924 0.334362532 YIL040W -- unknown -- unknown function YBR090C YBR090C 3.4 14.5 8.8 0.8463 0.787606238 iYBR090C 0.46183534 0.872872469 0.416048985 YBR090C -- unknown -- unknown function YPL086C ELP3 2 9 8.8 0.8463 0.419929315 iYPL086C 0.392190594 0.566226233 0.442284424 "ELP3 -- chromatin structure -- subunit of elongator/RNAPII holoenzyme, has histone acetyltransferase activity" YDR529C QCR7 6.1 26 8.7 0.8443 0.603493303 iYDR529C 0.392637278 0.558719969 0.345251397 "QCR7 -- respiration -- Ubiquinol cytochrome-c reductase subunit 7 (14 kDa protein), component of ubiquinol cytochrome-c reductase complex" YDR032C PST2 5.7 24 8.7 0.8443 0.116995695 iYDR032C-0 iYDR032C-1 0.395648302 0.7248602 0.288125828 0.177075619 0.758853151 PST2 -- unknown -- similarity to Ycp4p and S. pombe OBR1 brefeldin A resistance protein YDR099W BMH2 4.6 20 8.7 0.8443 0.38854806 iYDRCsigma1 YDRCdelta9 0.28383535 0.662836085 0.351677149 0.400642109 0.72330407 "BMH2 -- unknown -- Homolog of mammalian 14-3-3 protein, has strong similarity to Bmh1p" YFL005W SEC4 4.4 19 8.7 0.8443 0.735546458 iYFL006W 0.262452806 0.737580264 0.104934099 "SEC4 -- secretion -- GTP-binding vesicular transport between Golgi and plasma membrane, member of rab family in the ras superfamily" YFR050C PRE4 4.2 17 8.7 0.8443 0.637744749 iYFR050C 0.451301671 0.860761705 0.238148444 PRE4 -- protein degradation -- Proteasome subunit beta7_scinvolved in cleavage on the C-terminal side of acidic residues YLL067C YLL067C 3.5 15 8.7 0.8443 0.93690575 iYLL067C-0 iYLL067C-1 0.984077498 0.997782381 0.288269417 0.820198435 0.014152884 YLL067C -- unknown -- Protein similar to other subtelomerically-encoded proteins YBR079C RPG1 3.3 14 8.7 0.8443 0.498596486 iYBR079C 0.475308815 0.476283301 0.505167673 "RPG1 -- protein synthesis -- Translation initiation factor eIF3, p110 subunit" YER048C CAJ1 2.9 12 8.7 0.8443 0.849232277 iYER048C YERCdelta8 0.345806581 0.423943708 0.681165204 0.447711892 0.550663871 "CAJ1 -- unknown -- Homolog of E. coli DnaJ, has a leucine zipper" YIR022W SEC11 2.9 13 8.7 0.8443 0.44215773 iYIR021W 0.631501369 0.684982275 0.64757673 SEC11 -- secretion -- Signal sequence processing signal peptide cleavage and normal rate of secretion YML067C ERV41 2.7 12 8.7 0.8443 0.702132366 iYML067C 0.868975124 0.692233323 0.951083159 ERV41 -- unknown -- unknown function YJL002C OST1 4.5 19 8.6 0.8431 0.587293862 iYJL002C 0.485607212 0.671856094 0.814814815 "OST1 -- protein glycosylation -- Oligosaccharyltransferase alpha subunit, member of a complex of 8 ER proteins that transfers core oligosaccharide from dolichol carrier to Asn-X-Ser/Thr motif" YPL013C YPL013C 4.3 19 8.6 0.8431 0.06482524 iYPL013C 0.148858047 0.059902905 0.119787045 YPL013C -- protein synthesis -- similarity to Neurospora crassa mitochondrial ribosomal protein S24 YER120W SCS2 3.5 15 8.6 0.8431 0.386658345 0.648163068 SCS2 -- inositol metabolism -- Type II integral ER membrane the activation of INO1 expression YNL147W LSM7 2.8 12 8.6 0.8431 0.445116722 iYNL148C 0.285741962 0.799441341 0.336093275 LSM7 -- mRNA splicing (putative) -- U6 snRNA-associated Sm class YPL252C YAH1 2.7 12 8.6 0.8431 0.223386819 0.048560136 YAH1 -- unknown -- similarity to adrenodoxin and ferrodoxin YJR063W RPA12 1.8 8 8.6 0.8431 0.439296915 iYJR062C 0.405049637 0.702771206 0.312575623 RPA12 -- transcription -- RNA polymerase I subunit A12.2 YMR229C RRP5 2.6 11 8.5 0.8417 1 0.617939924 iYMR229C 0.98122463 0.580368859 0.658949746 RRP5 -- rRNA processing -- processing of pre-rRNA to 18S and 5.8S rRNA YMR071C YMR071C 4 17 8.5 0.8417 0.244254176 iYMR071C 0.159902764 0.308350804 0.073842514 YMR071C -- unknown -- unknown function YLL066C YLL066C 3.6 16.5 8.5 0.8417 0.950016335 iYLL066C-0 iYLL066C-1 0.983384079 0.997405681 0.39514295 0.843510527 0.029375463 "YLL066C -- unknown -- near identity to other subtelomerically-encoded proteins including Yhl050p, Yil177p, and Yhr219p" YML078W CPR3 3.5 15 8.5 0.8417 0.578144029 iYML079W 0.608078975 0.748869749 0.323443989 CPR3 -- protein folding -- Cyclophilin (peptidylprolyl cis-trans isomerase or PPIase) of mitochondria YNL046W YNL046W 3.1 14 8.5 0.8417 0.121741946 iYNL047C 0.320122196 0.287838392 0.30922609 YNL046W -- unknown -- unknown function YMR038C LYS7 2.6 12 8.5 0.8417 0.208147414 iYMR038C 0.255390395 0.294094174 0.215697346 LYS7 -- oxidative stress response -- Copper chaperone for superoxide dismutase Sod1p YMR272C SCS7 2.2 10 8.5 0.8417 0.414845626 iYMR272C 0.21152344 0.609811566 0.336775026 SCS7 -- fatty acid metabolism -- Ceramide hydroxylase that hydroxylates the C-26 fatty-acyl moiety of inositol-phosphorylceramide YGR183C QCR9 5.7 25 8.4 0.84 0.869132146 iYGR183C 0.480520186 0.792365479 0.490653389 QCR9 -- oxidative phosphorylation -- Ubiquinol cytochrome-c reductase subunit 9 (7.3 kDa protein)component of ubiquinol cytochrome-c reductase complex YBL005W-B 4.8 20 8.4 0.84 0.566023706 0.812807801 YBR096W YBR096W 4.8 21 8.4 0.84 0.687327379 iYBR095C 0.557440309 0.905964853 0.421446987 "YBR096W -- unknown -- unknown function, has a role in pseudohyphal growth and in resistance to elevated concentrations of NaCl and H2O2" YJR045C SSC1 4.3 19 8.4 0.84 0.940872164 iYJR045C 0.200441981 0.950119713 0.019168291 "SSC1 -- mitochondrial protein targeting -- Mitochondrial acts as an import motor with Tim44p and plays a chaperonin role in receiving and folding of protein chains during import, heat shock HSP70 family" YKL067W YNK1 3.9 17 8.4 0.84 0.173922298 iYKL068W itH(GUG)K 0.582759426 0.617986271 0.268411092 0.77184249 0.312197873 "YNK1 -- nucleotide metabolism -- Nucleoside diphosphate kinase, responsible for synthesis of all nucleoside triphosphates except ATP" YDR174W HMO1 3.3 14 8.4 0.84 0.571349012 iYDR173C 0.206121069 0.941195582 0.670022064 "HMO1 -- chromatin structure -- DNA helicase with HMG-box DNA-binding domain, interacts with FK506-binding protein Fpr1p" YDR092W UBC13 3.1 14 8.4 0.84 0.340038596 iYDR091C 0.42983511 0.631763767 0.879809631 "UBC13 -- protein degradation, ubiquitin-mediated -- Ubiquitin-conjugating (E2) enzyme" YGL020C YGL020C 3.1 14 8.4 0.84 0.727316437 iYGL020C 0.087253562 0.9013471 0.089424951 YGL020C -- unknown -- unknown function YNR061C YNR061C 2.9 13 8.4 0.84 0.218229337 iYNR061C 0.484790524 0.251181355 0.485476837 YNR061C -- unknown -- unknown function YGR295C COS6 4.5 20 8.3 0.839 0.935034713 iYGR295C-0 iYGR295C-1 0.992972767 0.997490691 0.673902634 0.323992853 0.002715379 COS6 -- unknown -- Member of COS family of subtelomerically-encoded proteins YDR346C YDR346C 2.9 13 8.3 0.839 0.470440964 iYDR346C 0.197126888 0.739488192 0.192007797 YDR346C -- unknown -- unknown function YJL192C YJL192C 2.9 13 8.3 0.839 0.982134047 iYJL192C 0.979489177 0.609730344 0.718175959 YJL192C -- unknown -- weak similarity to E. coli phosphoribosylformylglycinamide synthase YHR121W YHR121W 2.8 12 8.3 0.839 0.95870152 iYHR120W 0.910640245 0.115642458 0.606065443 YHR121W -- unknown -- unknown function YNR044W AGA1 2.4 11 8.3 0.839 0.025687298 iYNR043W 0.282409715 0.076591943 0.335481792 AGA1 -- mating -- a-Agglutinin anchor subunit YEL031W SPF1 4.4 20 8.2 0.8378 0.95669654 iYEL032W 0.684989473 0.683713802 0.772798742 "SPF1 -- transport -- Putative Ca2+-transporting ATPases, member of P-type ATPase superfamily" YHR018C ARG4 3.5 16 8.2 0.8378 0.57567086 iYHR018C 0.511661224 0.980047885 0.340476958 ARG4 -- arginine biosynthesis -- Argininosuccinate lyasecatalyzes the final step in arginine biosynthesis YDL064W UBC9 2.9 13 8.2 0.8378 0.594259989 iYDL065C 0.641216796 0.468954509 0.547326417 "UBC9 -- protein degradation, ubiquitin-mediated -- Smt3p-conjugating enzyme required for G2/M transition" YLR276C DBP9 2.5 11 8.2 0.8378 0.418000653 iYLR276C 0.768148341 0.767766395 0.840059399 DBP9 -- unknown -- similarity to DEAD box RNA helicases YNR017W TIM23 2.5 11 8.2 0.8378 0.698376522 iYNR016C-0 iYNR016C-1 0.025447048 0.004345731 0.944692737 0.032008558 0.055652486 "TIM23 -- mitochondrial protein targeting -- Mitochondrial inner membrane import of proteins destined for the mitochondrial matrix, part of translocation channel with Tim17p/Mpi2p" YJL178C YJL178C 2.4 11 8.2 0.8378 0.966475704 iYJL178C 0.981795382 0.84039961 0.180526736 YJL178C -- unknown -- unknown function YPL111W CAR1 2.6 12 8.1 0.8356 1 0.968531216 iYPL112C tM(CAU)P 0.577330501 0.688328293 0.317434741 0.150331936 0.365241636 "CAR1 -- arginine metabolism -- Arginase, catalyzes the first step in arginine degradation and acts as an allosteric regulator of ornithine carbamyltransferase" YOR340C RPA43 2.4 11 8.1 0.8356 1 0.869044945 iYOR340C 0.960055208 0.458414555 0.723278203 RPA43 -- transcription -- RNA polymerase I subunitnot shared with other polymerases YPL227C ALG5 2.2 10 8.1 0.8356 1 0.96980735 iYPL227C 0.955560952 0.323463687 ALG5 -- protein glycosylation -- Dolichol-P-glucose synthetase YMR314W PRE5 4 19 8.1 0.8356 0.600978929 iYMR313C 0.487248705 0.763350613 0.489508763 PRE5 -- protein degradation -- Proteasome subunit alpha6_sc YGL231C YGL231C 3.9 18 8.1 0.8356 0.424002804 iYGL231C 0.625241301 0.884916201 0.160957414 YGL231C -- unknown -- unknown function YJL008C CCT8 3.5 16 8.1 0.8356 0.806297555 iYJL008C YJLWtau4 0.549110517 0.733113428 0.965522745 0.848766475 0.907844165 CCT8 -- protein folding -- Component of Chaperonin-containing T-complex YDR432W NPL3 3.1 14 8.1 0.8356 0.113381481 iYDR431W 0.54126941 0.154889539 0.39639893 "NPL3 -- mRNA export; protein import -- 18S and 25S rRNA processing, export of RNA from the nucleus, import of proteins into the nucleus, associated with U1 snRNP, has 2 RNA recognition (RRM) domains" YNL231C PDR16 2.7 12 8.1 0.8356 0.671614179 iYNL231C 0.154565129 0.747644574 0.257642978 PDR16 -- drug resistance -- lipid biosynthesis and multidrug resistance YGL186C YGL186C 2.4 11 8.1 0.8356 0.686076412 iYGL186C 0.523192348 0.770615073 0.655422374 YGL186C -- unknown -- Member of purine/cytosine permease family of membrane transporters YOR108W YOR108W 2.4 11 8.1 0.8356 0.312332549 iYOR107W 0.649049541 0.813790834 0.656529806 YOR108W -- unknown -- Alpha-isopropylmalate syntase II YER127W LCP5 2 9 8.1 0.8356 0.197464561 iYER126C 0.474346952 0.710968572 0.250119713 "LCP5 -- rRNA processing, putative -- ribosomal RNA processing" YCR053W THR4 7.4 34 8 0.8334 0.150040762 iYCR052W 0.577791628 0.45578198 0.670287172 "THR4 -- threonine biosynthesis -- Threonine synthase (O-P-homoserine P-lyase), second and final step of threonine biosynthesis pathway" YDR328C SKP1 5.8 27 8 0.8334 0.300167366 iYDR328C 0.333533513 0.687237719 0.333055866 SKP1 -- mitosis -- Component (subunit d) of Cbf3 kinetochore complex and component with Cdc53p and Cdc34p of SCF (Skp1p-cullin-F-box) complexes which target many proteins for ubiquitin-dependent degradation YDR177W UBC1 4.9 23 8 0.8334 0.417000431 iYDR176W 0.227623521 0.941911054 0.313704929 "UBC1 -- protein degradation, ubiquitin-mediated -- Ubiquitin conjugating enzyme (E2) that plays a role early in spore germination" YOL123W HRP1 3.8 18 8 0.8334 0.51509159 iYOL124C 0.531809555 0.556102283 0.876695164 "HRP1 -- mRNA processing -- Nuclear polyadenylated RNA-binding protein, has 2 RNA recognition (RRM) domains" YPR041W TIF5 3.6 17 8 0.8334 0.638450628 iYPR040W 0.471832803 0.76009577 0.390779766 "TIF5 -- protein synthesis -- Translation initiation factor eIF5, catalyzes hydrolysis of GTP on the 40S ribosomal subunit-initiation complex followed by joining to 60S ribosomal subunit" YOR286W YOR286W 3.5 16 8 0.8334 0.465823365 iYOR285W 0.433317016 0.45405311 0.459783062 YOR286W -- unknown -- similarity to Drosophila melanogaster heat shock protein 67B2 YGL234W "ADE5,7" 3.4 16 8 0.8334 0.577116734 iYGL235W 0.048600987 0.579678363 0.120931357 "ADE5,7 -- purine biosynthesis -- Phosphoribosylamine-glycine ligase (GARSase) plus Phosphoribosylformylglycinamidine cyclo-ligase (AIRSase)bifunctional protein" YER003C PMI40 2.5 11 8 0.8334 0.383549981 iYER003C 0.322021823 0.41641822 0.321243726 "PMI40 -- mannose metabolism -- Mannose-6-phosphate isomerase, generates mannose-6-phosphate for synthesis of GDP-mannose and dolichol-phosphate-mannose" YOR067C ALG8 2.2 10 8 0.8334 0.148279561 iYOR067C 0.665862931 0.558804418 0.291522142 ALG8 -- protein glycosylation -- Glucosyltransferase of endoplasmic reticulumhas a role in adding glucose to the dolichol-linked oligosaccharide precursor prior to transfer to protein YPL177C CUP9 2.2 10 8 0.8334 0.401352472 iYPL177C-0 iYPL177C-1 0.116130766 0.270232909 0.487616226 0.203700575 0.008540122 CUP9 -- Cu2+ ion homeostasis -- Homeodomain copper homeostasis and in regulation of peptide import YDR397C NCB2 1.8 9 8 0.8334 0.360284874 iYDR397C 0.123579382 0.820024574 0.116959064 NCB2 -- transcription -- Beta subunit of NC2 (Dr1/Drap1) repressor of class II transcription YDR298C ATP5 5.1 24 7.9 0.8311 0.63485276 iYDR298C 0.497548034 0.799629391 0.456493716 "ATP5 -- ATP synthesis -- Subunit 5 of F0-ATP synthase, oligomycin sensitivity-conferring subunit" YKL046C YKL046C 3.7 18 7.9 0.8311 0.351186363 iYKL046C 0.379005976 0.686826298 0.391872309 "YKL046C -- unknown -- unknown function, has 2 predicted transmembrane segments" YMR108W ILV2 3.7 17 7.9 0.8311 0.87395452 iYMR107W 0.105047516 0.917700252 0.05927223 "ILV2 -- isoleucine and valine biosynthesis -- Acetolactate synthase (acetohydroxyacid synthase), first step in valine and isoleucine biosynthesis pathway" YOR103C OST2 3.6 17 7.9 0.8311 0.674214206 iYOR103C 0.756728032 0.225219473 0.585688368 "OST2 -- protein glycosylation -- Oligosaccharyltransferase epsilon subunit, member of a complex of 8 ER proteins that transfers core oligosaccharide from dolichol carrier to Asn-X-Ser/Thr motif" YLR186W YLR186W 3.1 15 7.9 0.8311 0.669176115 iYLR185W 0.863732758 0.714185884 0.640509185 YLR186W -- unknown -- unknown function YPL239W YAR1 3.1 15 7.9 0.8311 0.48846389 iYPL240C 0.543840163 0.670684836 0.598686565 YAR1 -- unknown -- 2 ankyrin repeats YBR171W SEC66 3 14 7.9 0.8311 0.393311663 iYBR170C 0.449703662 0.719626168 0.624431449 "SEC66 -- secretion -- Component of ER protein-translocation subcomplex with Sec62p, Sec63p, Sec66p, and Sec72p" YGL009C LEU1 3 14 7.9 0.8311 0.500690826 iYGL009C 0.861306385 0.879535917 0.549640862 "LEU1 -- leucine biosynthesis -- 3-Isopropylmalate dehydratase, second step in leucine biosynthesis pathway" YGL001C ERG26 2.6 12 7.9 0.8311 0.857918912 iYGL001C CEN7 0.41465844 0.546346169 0.995402113 0.593457944 0.335471729 "ERG26 -- unknown -- C-3 sterol dehydrogenase, C-4 decarboxylase, required for ergosterol biosynthesis" YPL207W YPL207W 2.6 12 7.9 0.8311 0.116885968 iYPL208W 0.18787335 0.043778872 0.097076715 YPL207W -- unknown -- unknown function YPL266W DIM1 2.1 10 7.9 0.8311 0.275420168 iYPL267W 0.297796848 0.627661372 0.317998711 "DIM1 -- rRNA processing, 18S -- Dimethyladenosine transferase, (rRNA (adenine-N6,N6-)-dimethyltransferase), responsible for m6[2]Am6[2]A dimethylation in 3'-terminal loop of 18S rRNA" YIR026C YVH1 2 9 7.9 0.8311 0.574827941 iYIR026C 0.54780511 0.880604288 0.324771882 YVH1 -- sporulation -- Protein-tyrosine phosphatase (PTPase) with similarity to vaccinia VH1 YER031C YPT31 3.4 16 7.8 0.8299 1 0.982644965 iYER031C 0.969337599 0.844630672 0.112043236 "YPT31 -- secretion -- GTP-binding protein required in the secretory pathway at the stage of formation of trans-Golgi vesicles, member of rab family in the ras superfamily of small GTP-binding proteins" YNR036C YNR036C 3.4 16 7.8 0.8299 0.16909487 iYNR036C 0.264973194 0.165935673 0.254716981 "YNR036C -- unknown -- Putative mitochondrial ribosomal small subunit, has similarity to ribosomal protein S12" YEL058W PCM1 3.1 15 7.8 0.8299 0.509393838 iYEL059W 0.608920522 0.48420883 0.382561676 "PCM1 -- aminosugars metabolism -- Hexosephosphate mutase (phosphoacetylglucosamine mutase, N-acetylglucosamine-phosphate mutase)converts N-acetyl-D-glucosamine 1-phosphate to N-acetyl-D-glucosamine 6-phosphate" YDL213C YDL213C 3 14 7.8 0.8299 iYDL213C 0.337575486 0.291061169 "YDL213C -- unknown -- hydrophilin family, has an N-terminal RNA recognition (RRM) domain" YGL068W YGL068W 2.5 12 7.8 0.8299 0.839998585 0.910946197 "YGL068W -- unknown -- Putative mitochondrial ribosomal protein, possible homolog of E. coli L7/L12 ribosomal protein" YOR175C YOR175C 2.5 12 7.8 0.8299 0.361236842 iYOR175C 0.106501143 0.600225588 0.335887715 "YOR175C -- unknown -- weak similarity to Drosophila nessy, a putative transmemberne protein expressed in embryogenesis" YAR075W YAR075W 3.7 17 7.7 0.8283 0.966536145 0.403323385 "YAR075W -- unknown -- strong similarity to inosine-5'-monophosphate dehydrogenase, frameshifted from YAR073W, possible pseudogene" YNL104C LEU4 3.6 17 7.7 0.8283 0.390976602 iYNL104C 0.259169329 0.804791482 0.452465356 "LEU4 -- leucine biosynthesis -- 2-Isopropylmalate synthase, first step in leucine biosynthesis pathway" YDR378C LSM6 2.9 14 7.7 0.8283 0.633074387 iYDR378C 0.285153998 0.987246681 0.502540937 LSM6 -- mRNA splicing (putative) -- U6 snRNA-associated Sm-like group YHR042W NCP1 2.8 13 7.7 0.8283 0.521099191 iYHR041C 0.461805327 0.641509434 0.450996209 NCP1 -- microsomal electron transfer -- NADP-cytochrome P450 reductase YNL247W YNL247W 2.8 14 7.7 0.8283 0.144139474 iYNL248C 0.299300587 0.409597837 0.340079034 YNL247W -- protein synthesis -- Cysteinyl-tRNA synthetase YNR046W YNR046W 2.6 13 7.7 0.8283 0.081902244 iYNR045W 0.075006716 0.268923885 0.083896587 YNR046W -- unknown -- unknown function YDL112W TRM3 2.4 12 7.7 0.8283 0.588486148 iYDL113C 0.371309075 0.200451722 0.32555905 "TRM3 -- tRNA processing -- tRNA 2'-O-ribose methyltransferase, required for the formation of Gm18 modification" YER124C YER124C 2 10 7.7 0.8283 0.670533597 iYER124C 0.435684358 0.94557063 0.410598206 YER124C -- unknown -- unknown function YOR303W CPA1 4.5 22 7.6 0.8267 1 0.683860117 0.476855547 "CPA1 -- arginine biosynthesis -- Carbamoylphosphate synthase of arginine biosynthetic pathway, amidotransferase small subunit" YBR109C CMD1 8.3 41 7.6 0.8267 0.792213048 iYBR109C 0.057840957 0.910623538 0.016121309 "CMD1 -- signaling -- Calmodulin, calcium-binding many processes including cell polarization, nuclear division, and chromosome maintenance" YGR008C STF2 5.8 29 7.6 0.8267 0.377230152 iYGR008C 0.306027442 0.540856659 0.273910105 "STF2 -- ATP synthesis -- ATPase stabilizing factor, binds to F0-ATPasefacilitates binding of inhibitor and 9 kDa protein to F1-ATPase" YOR194C TOA1 2.8 14 7.6 0.8267 0.007097014 iYOR194C 0.082918644 0.007861635 0.030527442 "TOA1 -- transcription -- RNA polymerase II transcription initiation factor TFIIA, large chain" YJR015W YJR015W 2.5 12 7.6 0.8267 0.626912241 iYJR014W 0.184762849 0.890215375 0.342592593 YJR015W -- unknown -- similarity to Sng1p and multidrug resistance proteins YHR196W YHR196W 2.4 12 7.6 0.8267 0.615236845 iYHR195W 0.314299191 0.814977258 0.499758298 YHR196W -- unknown -- unknown function YHR005C GPA1 2.2 11 7.6 0.8267 0.669253484 iYHR005C 0.62192296 0.888028731 0.716860035 "GPA1 -- signaling, pheromone pathway -- Guanine nucleotide-binding protein alpha subunit of pheromone response pathway" YDR120C TRM1 1.9 9 7.6 0.8267 0.170766139 iYDR120C 0.18605031 0.535449565 0.173866535 "TRM1 -- tRNA processing -- N2,N2-dimethylguanine tRNA methyltransferase, required for methylation of G26 of both mitochondrial and cytoplasmic tRNAs" YPL135W ISU1 4.8 24 7.5 0.8248 0.550020721 iYPL136W 0.254161418 0.569273743 0.376705653 ISU1 -- iron homeostasis -- similarity to iron-sulfur cluster nitrogen fixation proteins YNL071W LAT1 4 20 7.5 0.8248 0.715286625 iYNL072W 0.026125519 0.889305666 0.183160234 LAT1 -- glycolysis -- Dihydrolipoamide S-acetyltransferase component (E2) of pyruvate dehydrogenase complex YKR080W MTD1 3.6 18 7.5 0.8248 0.768547818 iYKR079C 0.588401422 0.962781484 0.828391879 "MTD1 -- nucleotide metabolism -- NAD-dependent 5,10-methylenetetrahydrafolate dehydrogenase" YGR264C MES1 3.3 16 7.5 0.8248 0.67675218 0.921052632 "MES1 -- protein synthesis -- Methionyl-tRNA synthetase, cytoplasmic, member of class I aminoacyl tRNA synthetase family" YMR149W SWP1 3.1 15 7.5 0.8248 0.313129373 iYMR148W 0.224789541 0.764734581 0.197437629 "SWP1 -- protein glycosylation -- Oligosaccharyltransferase delta subunit, member of a complex of 8 ER proteins that transfers core oligosaccharide from dolichol carrier to Asn-X-Ser/Thr motif" YBR244W GPX2 2.9 14 7.5 0.8248 0.357867811 iYBR243C 0.593411041 0.796648045 "GPX2 -- mitochondrial morphology (putative) -- Glutathione peroxidase, has a role in mitochondrial morphology" YBR142W MAK5 2.6 13 7.5 0.8248 0.291587513 iYBR141C 0.169228227 0.68772156 0.030168589 "MAK5 -- mRNA splicing -- Probable pre-mRNA splicing RNA-helicase of DEAD box family, involved in maintenance of M double-stranded RNA (dsRNA) killer plasmid" YDR245W MNN10 2.6 13 7.5 0.8248 0.287917338 iYDR244W 0.591883066 0.479090184 0.618367692 "MNN10 -- cell wall biogenesis -- subunit of Anp1p-Hoc1p-Mnn10p-Mnn11p-Mnn9p mannosyltransferase complex, M-Pol II" YGL097W SRM1 2.4 12 7.5 0.8248 0.822014035 iYGL098W YGLWdelta4 0.169432383 0.716350866 0.965522916 0.358818835 0.376529833 SRM1 -- nuclear targeting; mating -- GDP/GTP exchange factor for Gsp1p and Gsp2p YDR087C RRP1 2.1 10 7.5 0.8248 0.102086804 iYDR087C 0.350778913 0.434557063 0.127214685 RRP1 -- rRNA processing -- maturation of 25S rRNA YLR179C YLR179C 5.1 25 7.4 0.8212 0.205407161 iYLR179C 0.447228947 0.912156167 0.398107469 YLR179C -- unknown -- similarity to Tfs1p Cdc25p-dependent nutrient- and ammonia-response protein YHR051W COX6 4 20 7.4 0.8212 0.826950314 iYHR050W 0.622466112 0.973093063 0.824660231 COX6 -- oxidative phosphorylation -- Cytochrome-c oxidase subunit VI YPR108W RPN7 4 20 7.4 0.8212 0.604802755 iYPR107C 0.174933676 0.560534591 0.247157245 RPN7 -- protein degradation -- Non-ATPase of 26S proteasome complex YMR276W DSK2 3.6 18 7.4 0.8212 0.571847595 iYMR275C 0.232602647 0.23308324 0.118272639 DSK2 -- spindle pole body dupl -- Protein required with Rad23p for duplication of spindle pole bodyhas similarity to ubiquitin YNL131W TOM22 3.6 18 7.4 0.8212 0.355847762 iYNL132W 0.339818313 0.602638015 0.546870222 TOM22 -- mitochondrial protein targeting -- Component of mitochondrial outer membrane receptor complexrequired for protein import and cell viability YLR028C ADE16 3.4 17 7.4 0.8212 0.548032816 iYLR028C 0.507563302 0.684748428 0.371842343 ADE16 -- purine biosynthesis -- 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR) transformylase/IMP cyclohydrolase YFR024C YFR024C 3 15 7.4 0.8212 0.120377727 0.678698034 "YFR024C -- unknown -- similarity to Ysc84p, Rvs167p, Abp1p, and Sla1p, has an SH3 domain" YML133C YML133C 2.9 14.5 7.4 0.8212 0.917350004 iYML133C-0 iYML133C-1 0.995641669 0.99633417 0.224142187 0.271280052 0.153711093 "YML133C -- unknown -- similarity to other subtelomerically-encoded proteins including Yer189p, and Yjl225p" YOR305W YOR305W 2.9 15 7.4 0.8212 0.209482119 iYOR304C-A 0.218545113 0.624197364 0.07750564 YOR305W -- unknown -- unknown function YBL068W PRS4 2.8 14 7.4 0.8212 0.695757457 iYBL069W 0.669010938 0.90548351 0.613168396 "PRS4 -- pentose phosphate cycle -- Phosphoribosylpyrophosphate synthetase (ribose-phosphate pyrophosphokinase), enxyme that synthesizes phosphoribosylpyrophosphate (PRPP) from ribose-5' phosphate and ATP" YOL126C MDH2 2.8 14 7.4 0.8212 0.616361338 iYOL126C 0.546030005 0.903041058 0.262753319 "MDH2 -- TCA cycle -- Malate dehydrogenase, cytosolic, probably functions in the glyoxylate cycle" YPR118W YPR118W 2.5 12 7.4 0.8212 0.425384234 iYPR117W 0.205214952 0.521707901 0.143431167 YPR118W -- unknown -- unknown function YPL129W ANC1 2.2 11 7.4 0.8212 0.108242802 iYPL130W 0.352764472 0.139051332 0.355056365 "ANC1 -- transcription -- RNA polymerase II transcription initiation factor TFIIF (factor g), small subunit, component of RNA polymerase holoenzyme, Kornberg's mediator (SRB) subcomplex, and the SWI-SNF complex" YDL166C YDL166C 2.1 11 7.4 0.8212 0.131560707 iYDL166C 0.626510243 0.149049307 0.590899182 YDL166C -- unknown -- Essential protein important for Skn7p-dependent transcription of target genes during oxidative stress YLL034C YLL034C 2.1 10 7.4 0.8212 0.296798323 iYLL034C 0.206500119 0.412423461 0.220354126 "YLL034C -- unknown -- similarity to mammalian valosin-containing protein (VCP), member of AAA family of ATPases" YKL165C MCD4 1.9 10 7.4 0.8212 0.685041282 iYKL165C itE(UUC)K 0.455150356 0.267804639 0.644878843 0.62849406 0.26458014 MCD4 -- sporulation -- glycosylphosphatidylinositol (GPI) anchor synthesis YLR154C YLR154C 1.9 9 7.4 0.8212 0.260904933 iYLR154C tQ(UUG)L 0.331777793 0.554422714 0.274586009 0.273283919 0.369034318 YLR154C -- unknown -- unknown function YJL145W YJL145W 1.7 8 7.4 0.8212 0.556785265 iYJL146W 0.38588311 0.874476313 0.42124475 YJL145W -- unknown -- unknown function YDL072C YDL072C 4.4 22 7.3 0.8196 0.352118337 iYDL072C 0.261075366 0.364997477 0.49277128 YDL072C -- unknown -- unknown function YGL080W YGL080W 3.5 18 7.3 0.8196 0.327557334 iYGL081W 0.332869385 0.685334244 0.074074074 YGL080W -- unknown -- unknown function YKL094W YJU3 3.4 17 7.3 0.8196 0.665950374 iYKL095W 0.305957547 0.914518208 0.257302474 YJU3 -- unknown -- unknown function YMR079W SEC14 2.7 14 7.3 0.8196 0.55349559 iYMR078C 0.482929292 0.685664788 0.54769392 SEC14 -- secretion -- Phosphatidylinositol/phosphatidylcholine (PI/PC)-transfer proteinrequired for transport of secretory proteins from Golgi complex YMR309C NIP1 2.6 13 7.3 0.8196 0.735932989 iYMR309C 0.479163994 0.791551854 0.373800113 "NIP1 -- nuclear protein targeting -- Subunit of translation initiation complex eIF3, also required for nuclear importhas weak similarity to Nsr1p" YOL103W ITR2 2.5 13 7.3 0.8196 0.175307593 iYOL104C iYOLWdelta5 0.162452487 0.226478275 0.467836257 0.401843684 0.045360079 "ITR2 -- transport -- Myo-inositol permease (minor), closely related to Itr1p, member of hexose transporter family of major facilitator superfamily (MFS)" YER154W OXA1 2.2 11 7.3 0.8196 0.220589363 iYER153C 0.051573364 0.812014194 0.070175439 OXA1 -- respiration -- assembly of F1F0-ATP synthase and cytochrome oxidase YDR365C YDR365C 2 10 7.3 0.8196 0.178003306 iYDR365C 0.192052934 0.6326136 0.276803119 YDR365C -- unknown -- unknown function YLR113W HOG1 4.5 23 7.2 0.8163 0.73510205 iYLR112W 0.776586565 0.673742138 0.20609088 "HOG1 -- signaling, high osmolarity pathway -- MAP kinase (MAPK) central to the high-osmolarity signal transduction pathway" YDL015C YDL015C 4.3 22 7.2 0.8163 0.595386909 iYDL015C 0.800695409 0.675486005 0.311204324 YDL015C -- unknown -- similarity to rat synaptic glycoprotein SC2 YHR190W ERG9 4 21 7.2 0.8163 0.393444492 iYHR189W 0.259310876 0.484623184 0.009976057 "ERG9 -- sterol metabloism -- Squalene synthetase (farnesyl-diphosphate farnesyltransferase), acts at a branch point in the isoprenoid biosynthesis pathway" YOR198C BFR1 3.3 17 7.2 0.8163 0.246478292 iYOR198C 0.314674164 0.239035088 0.021206489 BFR1 -- secretion -- can suppress brefeldin A-induced lethality when overexpressed YER006W YER006W 2.6 13 7.2 0.8163 0.404329691 iYER005W 0.176898372 0.558250081 0.157669462 "YER006W -- unknown -- Nuclear unknown function, has similarity to mouse Mmr1 protein" YJL014W CCT3 2.6 13 7.2 0.8163 0.590003267 0.724018761 "CCT3 -- protein folding -- Component of Chaperonin-containing T-complex (TCP ring complex, TRiC)homologous to mouse CCT3" YJR016C ILV3 2.5 13 7.2 0.8163 0.384397367 iYJR016C 0.8273836 0.807701802 0.690013518 "ILV3 -- isoleucine and valine biosynthesis -- Dihydroxyacid dehydratase (DAD), third step in valine and isoleucine biosynthesis pathway" YKR085C MRPL20 2.5 13 7.2 0.8163 0.235067128 iYKR085C 0.326876682 0.321329407 0.369234801 MRPL20 -- protein synthesis -- Mitochondrial ribosomal large subunit (YmL20) YMR058W FET3 2.5 13 7.2 0.8163 0.656912027 iYMR057C 0.618276262 0.908445592 0.266799681 FET3 -- transport -- Cell surface ferroxidaserequired for high-affinity ferrous iron uptake YPR063C YPR063C 2.5 12 7.2 0.8163 0.457283099 iYPR063C 0.395372382 0.757734451 0.83345676 YPR063C -- unknown -- unknown function YER073W ALD5 2.1 11 7.2 0.8163 0.933783859 iYER072W 0.860631437 0.83270146 0.932127883 ALD5 -- fermentation -- Mitochondrial aldehyde dehydrogenase YFR001W LOC1 2.1 11 7.2 0.8163 0.459378052 CEN6 iCEN6 0.542307057 0.60528639 0.372379455 0.372617421 0.476589797 "LOC1 -- unknown -- binds double-stranded RNA, involved in localization of mRNA" YNL283C WSC2 2.1 11 7.2 0.8163 0.043011366 iYNL283C 0.533663139 0.167621199 0.266422082 WSC2 -- cell wall biogenesis -- maintenance of cell wall integrity and for the stress response YEL044W YEL044W 2 11 7.2 0.8163 0.713693058 iYEL045C 0.917222031 0.599190629 0.332196231 YEL044W -- unknown -- unknown function YMR290C HAS1 1.8 9 7.2 0.8163 0.192429781 0.510071475 HAS1 -- unknown -- RNA helicase of DEAD/DEAH box family YPR112C MRD1 1.7 8 7.2 0.8163 0.485706942 iYPR112C 0.202915079 0.269854681 0.151904263 "MRD1 -- unknown -- similarity to Pab1p, Pub1p, Nsr1p, Nop4p and other RNA-binding proteins, contains four RNA recognition (RRM) domains" YER070W RNR1 1.5 8 7.2 0.8163 0.848796197 iYER069W 0.446775551 0.845223402 0.516679968 "RNR1 -- DNA replication -- Ribonucleotide reductase (ribonucleoside-diphosphate reductase) large subunit, converts deoxyribonucleoside diphosphate to ribonucleoside diphosphate" YNL002C RLP7 1.9 10 7.1 0.8145 1 0.464471498 iYNL002C 0.553694885 0.450743494 0.268587361 "RLP7 -- protein synthesis -- similarity to ribosomal proteins including Rpl6p, gene has low codon bias" YDR427W RPN9 5.3 28 7.1 0.8145 0.88126369 iYDR426C 0.28111056 0.904628891 0.49324096 "RPN9 -- protein degradation -- Non-ATPase subunit of 26S proteasome complex, required for efficient assembly of complex" YDL029W ARP2 4.8 25 7.1 0.8145 0.33299074 iYDL030W 0.566036693 0.415617543 0.407669997 ARP2 -- cytoskeleton -- Actin-related ARP2/3 complexinvolved in cell polarity and endocytosis YHR200W RPN10 3.6 19 7.1 0.8145 0.611380929 iYHR199C 0.367103494 0.764587701 0.334957765 RPN10 -- protein degradation -- Non-ATPase component of 26S proteasome complex YGR210C YGR210C 3 16 7.1 0.8145 0.649272114 iYGR210C 0.892957974 YGR210C -- unknown -- unknown function YAL023C PMT2 2.7 14 7.1 0.8145 0.544815492 iYAL023C 0.588671588 0.667438148 0.455031679 PMT2 -- protein glycosylation -- Mannosyltransferase(dolichyl phosphate-D-mannose YDR487C RIB3 2.5 13 7.1 0.8145 0.799260391 iYDR487C 0.388638018 0.96149885 0.324110672 "RIB3 -- flavin biosynthesis -- DBP synthase(3,4-dihydroxy-2-butanone 4-phosphate synthase), part of riboflavin biosynthesis pathway" YGR044C RME1 2.1 11 7.1 0.8145 0.319374024 0.710769981 RME1 -- meiosis -- Zinc-finger transcription factor that represses meiosis in non-a/alpha cells YHR085W YHR085W 1.5 8 7.1 0.8145 0.390857897 iYHR084W 0.205833746 0.416991553 0.221673661 YHR085W -- unknown -- unknown function YOR341W RPA190 2 11 7 0.8125 1 0.649767524 iYOR340C 0.960055208 0.299707602 0.723278203 RPA190 -- transcription -- RNA polymerase I largest subunit YCR051W YCR051W 2.8 15 7 0.8125 0.483814231 iYCR050C 0.871142118 0.438830686 0.823344358 YCR051W -- unknown -- similarity to ankyrin and coiled-coil protein YMR235C RNA1 2.8 15 7 0.8125 0.157116635 iYMR235C 0.34936877 0.35046729 0.215778011 "RNA1 -- RNA export -- GTPase-activating (GAP) protein for Gsp1p (Ran), involved in nuclear export" YIL047C SYG1 2.7 14 7 0.8125 0.48920618 iYIL047C 0.101755046 0.509236106 0.002842755 "SYG1 -- signaling (putative) -- for which truncation and overexpression can suppress lethality of Gpa1p deficiency, member of divalent anion" YHL011C PRS3 2.5 13 7 0.8125 0.50512678 iYHL011C 0.14770467 0.59792498 0.038609364 "PRS3 -- purine biosynthesis -- Phosphoribosylpyrophosphate synthetase (ribose-phosphate pyrophosphokinase II)component of yeast 20S proteasome, with a role in cell cycle regulation" YHR070W YHR070W 2.4 13 7 0.8125 0.492161749 iYHR069C 0.80025672 0.552209331 0.198376532 YHR070W -- unknown -- similarity to met-10+ of Neurospora crassa YBL112C 2.2 12 7 0.8125 0.895891251 0.447389623 YDR531W YDR531W 2.2 12 7 0.8125 0.174441562 iYDR530C 0.491280253 0.465892053 0.326257862 YDR531W -- unknown -- Putative panthothenate kinase involved in coenzyme A biosynthesis YDR165W YDR165W 2 11 7 0.8125 0.700336798 iYDR164C 0.729258102 0.95990566 0.889445672 YDR165W -- unknown -- unknown function YGR245C SDA1 1.7 9 7 0.8125 0.095658125 iYGR245C 0.17284577 0.089668616 0.143954369 SDA1 -- unknown -- Essential normal organization of actin cytoskeleton YMR256C COX7 3.8 21 6.9 0.8103 0.725621031 iYMR256C 0.709092655 0.6422463 0.642382949 "COX7 -- oxidative phosphorylation -- Cytochrome-c oxidase, subunit VII" YDR377W ATP17 3.6 19 6.9 0.8103 0.912769934 iYDR376W 0.60733812 0.997990915 0.525046382 ATP17 -- ATP synthesis -- ATP synthase subunit f YIL109C SEC24 3.6 19 6.9 0.8103 0.081937454 iYIL109C 0.509956289 0.545037061 0.519585702 SEC24 -- secretion -- Component of COPII coat of vesiclesinvolved in endoplasmic reticulum to Golgi transport YMR215W YMR215W 3.6 19 6.9 0.8103 0.273499611 iYMR214W 0.406459333 0.552387914 0.592365785 YMR215W -- unknown -- similarity to Gas1p YKL077W YKL077W 3.4 18 6.9 0.8103 0.845085284 iYKL078W 0.603854443 0.956171447 0.675690637 YKL077W -- unknown -- unknown function YML132W COS3 3 16 6.9 0.8103 0.933750101 iYML133C-0 iYML133C-1 0.995641669 0.99633417 0.660015962 0.271280052 0.153711093 COS3 -- unknown -- Member of COS family of subtelomerically-encoded proteins YEL038W UTR4 2.9 16 6.9 0.8103 0.605850273 iYEL039C 0.41910428 0.707635506 0.432215234 UTR4 -- unknown -- unknown function YJL111W CCT7 2.7 14 6.9 0.8103 0.388440516 iYJL112W 0.633701371 0.756489747 0.731386626 "CCT7 -- protein folding -- Component of Chaperonin-containing T-complex (TCP ring complex, TRiC), has similarity to Tcp1p" YDL008W APC11 2.1 11 6.9 0.8103 0.365208541 iYDL009C 0.616924038 0.796241026 0.635913807 "APC11 -- mitosis -- Component of anaphase-promoting complex (APC), required for Clb2p degradation and for the metaphase-anaphase transition" YOR243C YOR243C 1.9 10 6.9 0.8103 0.146886504 iYOR243C 0.430019062 0.558479532 0.498515024 YOR243C -- unknown -- unknown function YHR066W SSF1 1.7 9 6.9 0.8103 0.410614279 iYHR065C 0.765501052 0.414547848 0.436728395 SSF1 -- mating (putative) -- potential role in mating YER002W YER002W 3.4 18 6.8 0.8092 0.265380315 iYER001W 0.178562588 0.047677063 0.467048018 YER002W -- unknown -- Nuclear unknown function YDR339C YDR339C 2.7 15 6.8 0.8092 0.589689528 iYDR339C 0.644579552 0.812454626 0.610960257 "YDR339C -- unknown -- unknown function, with strong similarity to C. elegans and human proteins of unknown function" YJL117W PHO86 2.7 15 6.8 0.8092 0.498981572 iYJL118W 0.116835612 0.822589099 0.053721174 "PHO86 -- transport -- associated with phosphate transport complex, regulates Pho81p" YPR088C SRP54 2.5 14 6.8 0.8092 0.105112708 iYPR088C 0.070565175 0.311311634 0.053197065 SRP54 -- secretion -- Signal recognition particle subunit YML113W DAT1 2.4 13 6.8 0.8092 0.156586725 iYML114C 0.582617619 0.186754753 0.662809258 "DAT1 -- transcription (putative) -- Datin, oligo (DA)/oligo (DT)-binding protein" YDR060W YDR060W 2 11 6.8 0.8092 0.507637035 iYDR059C 0.641611062 0.308945713 0.794094174 YDR060W -- unknown -- 60S ribosomal subunit biogenesis YEL036C ANP1 3 17 6.7 0.805 1 0.765967132 iYEL036C 0.940501863 0.250719768 0.175717048 "ANP1 -- protein glycosylation -- cis Golgi with a role in retention of glycosyltransferases in the Golgi, subunit of Anp1p-Hoc1p-Mnn11p-Mnn9p mannosyltransferase complex" YNL138W SRV2 4.4 25 6.7 0.805 0.382640869 iYNL139C 0.331354701 0.841922947 0.727924589 SRV2 -- signaling -- Adenylate cyclase-associated protein (CAP) that may provide a link between growth signals and the cytoskeleton YER136W GDI1 4.3 24 6.7 0.805 0.52560336 iYER135C itV(AAC)E1 0.799137616 0.35467646 0.859410248 0.827442056 0.383560539 GDI1 -- secretion -- GDP dissociation inhibitor YGR253C PUP2 3.7 21 6.7 0.805 0.525683303 iYGR253C-0 iYGR253C-1 0.731051944 0.860937648 0.648140679 0.482618583 0.286793372 PUP2 -- protein degradation -- Proteasome subunit alpha5_sc (protease yscE subunit PUP2) YIL021W RPB3 3.3 18 6.7 0.805 0.785479127 iYIL022W 0.430581236 0.914011454 0.225346439 "RPB3 -- transcription -- RNA polymerase II, third-largest subunit (B45)" YML009C MRPL39 3 16 6.7 0.805 0.399748488 iYML009C 0.324211402 0.320378506 0.066467934 MRPL39 -- protein synthesis -- Mitochondrial ribosomal large subunit YKL016C ATP7 2.8 16 6.7 0.805 0.906709635 iYKL016C 0.917633344 0.904815681 0.790686432 "ATP7 -- ATP synthesis -- Subunit 7 of F0-ATP synthase, homolog of bovine F0-ATP synthase subunit d" YML086C ALO1 2.7 15 6.7 0.805 0.427928767 iYML086C 0.71614152 0.848359324 0.766771488 "ALO1 -- D-erythroascorbic acid biosynthesis -- D-arabinino-1,4-lactone oxidase (L-galactono-gamma-lactone oxidase)" YBR218C PYC2 2.4 13 6.7 0.805 0.562328061 iYBR218C 0.264213679 0.526360257 0.263474039 PYC2 -- TCA cycle -- Pyruvate carboxylase 2 YDR156W RPA14 2.4 13 6.7 0.805 iYDR155C 0.292725389 0.497271513 RPA14 -- transcription -- RNA polymerase I subunit A14 YLR214W FRE1 2.4 13 6.7 0.805 0.640901943 iYLR213C 0.897660006 0.493832376 0.601580879 FRE1 -- iron homeostasis -- Membrane-associated flavocytochrome with ferric and cupric reductase activitiesacts on ferric iron chelates external to the cell to facilitate iron uptake YGR079W YGR079W 2.2 12 6.7 0.805 0.450947988 iYGR078C 0.577788571 0.777526821 0.738872645 YGR079W -- unknown -- unknown function YNL061W NOP2 2.1 12 6.7 0.805 0.166020453 iYNL062C 0.368487236 0.301330033 0.317901235 "NOP2 -- nuclear organization -- Nucleolar protein, has strong similarity to human proliferation-associated p120 nucleolar antigen" YNL280C ERG24 2.1 12 6.7 0.805 0.379771939 iYNL280C 0.156579657 0.68128655 0.485601355 "ERG24 -- sterol metabolism -- C-14 sterol reductasecarries out reduction of delta 14,15 double bond of ergosterol precursor 4,4-dimethylcholesta-8,24,24 trienol" YGL255W ZRT1 2 11 6.7 0.805 0.696211854 iYGL256W-0 iYGL256W-1 0.266661307 0.366943116 0.878588553 0.395711501 0.365551193 "ZRT1 -- transport -- High-affinity zinc transport protein, member of ZIP family of metal ion transporters" YDR412W YDR412W 1.9 11 6.7 0.805 0.225017358 iYDR411C 0.42703309 0.301332034 0.27559399 YDR412W -- unknown -- Cytoplasmic unknown function YKL154W SRP102 1.9 10 6.7 0.805 0.702027599 iYKL155C 0.256943554 0.720858161 0.16588785 "SRP102 -- secretion -- Signal recognition particle receptor beta subunit, interacts with alpha subunit Srp101p" YLR435W YLR435W 1.9 10 6.7 0.805 0.228651022 0.319074425 YLR435W -- unknown -- unknown function YJL198W YJL198W 1.8 10 6.7 0.805 0.468967616 iYJL199C 0.144337803 0.667278532 0.105347167 "YJL198W -- unknown -- strong similarity to Pho87p and Ynr013p, member of phosphate permease family of membrane transporters" YDL201W YDL201W 1.7 10 6.7 0.805 0.073775607 iYDL202W 0.669902673 0.29702729 0.613840204 "YDL201W -- unknown -- Putative methyltransferase, highly conserved among eukaryotes" YDR361C YDR361C 1.7 9 6.7 0.805 0.736145643 iYDR361C 0.463907813 0.975192173 0.794795359 YDR361C -- unknown -- unknown function YDR404C RPB7 3.1 17 6.6 0.8024 0.585037875 iYDR404C 0.286281723 0.96217079 0.306606437 "RPB7 -- transcription -- RNA polymerase II, non-essential subunit, not shared" YEL051W VMA8 3 17 6.6 0.8024 0.657085927 iYEL052W 0.696381249 0.707980846 0.688853948 VMA8 -- vacuolar acidification -- Vacuolar H(+)-ATPase (V-ATPase) subunit of V1 catalytic sector YOL049W GSH2 3 17 6.6 0.8024 0.174334571 iYOL050C 0.089338728 0.431311254 0.131659999 "GSH2 -- glutathione biosynthesis -- Glutathione synthetase, carries out synthesis of glutathione from gamma-glutamylcysteine and glycine" YBR263W SHM1 2.9 17 6.6 0.8024 0.351510264 0.618133419 "SHM1 -- one-carbon interconversion -- Serine hydroxymethyltransferase (glycine hydroxymethyltransferase), mitochondrial" YDR072C IPT1 2.8 16 6.6 0.8024 0.702036474 iYDR072C 0.501691559 0.915529565 0.548567435 "IPT1 -- sphingolipid biosynthesis -- Inositolphosphotransferase 1, required for synthesis of mannosyl diphosphorylinositol ceramide (M(IP)2C) the most abundant and complex sphingolipid" YJL123C YJL123C 2.7 15 6.6 0.8024 0.154420719 iYJL123C 0.111162923 0.138068635 0.025086715 YJL123C -- unknown -- unknown function YMR089C YTA12 2.6 15 6.6 0.8024 0.240781075 iYMR089C 0.352043753 0.497482131 0.599760575 "YTA12 -- protein folding -- Mitochondrial protein involved with Afg3p in proteolytic and chaperonin activities in the inner membrane, member of AAA family of ATPases" YKL004W AUR1 2.5 14 6.6 0.8024 0.647259987 iYKL005C 0.243838337 0.731305961 0.361101724 AUR1 -- sphingolipid metabolism -- Phosphatidylinositol YML127W YML127W 2.4 14 6.6 0.8024 0.128195395 iYML128C 0.421654812 0.402078405 0.44837783 YML127W -- unknown -- unknown function YPL243W SRP68 2.4 13 6.6 0.8024 0.500880026 iYPL244C 0.098721762 0.577566602 0.105181936 SRP68 -- secretion -- Signal recognition particle subunit YPL199C YPL199C 2.2 12 6.6 0.8024 0.934641048 iYPL199C SNR59 0.943936035 0.815888078 0.840223464 0.325401307 0.451556265 YPL199C -- unknown -- unknown function YPL244C YPL244C 1.8 10 6.6 0.8024 0.097589701 iYPL244C 0.098721762 0.085873903 0.105181936 YPL244C -- unknown -- unknown function YGL171W ROK1 1.6 9 6.6 0.8024 0.207544115 iYGL172W 0.354930539 0.497243479 0.531795947 "ROK1 -- rRNA processing -- ATP-dependent RNA helicase required for rRNA processing, member of DEAD box family" YKL035W UGP1 5.5 31 6.5 0.7995 0.651147033 0.495356578 UGP1 -- pyrimidine metabolism -- UDP-glucose pyrophosphorylase (UTP-glucose-1-P uridylyltransferase) YGL206C CHC1 3.4 19 6.5 0.7995 0.715544482 iYGL206C 0.298483591 0.575292398 0.832943454 "CHC1 -- endocytosis and secretion -- Clathrin heavy chain, required for the internalization step of endocytosis" YDL128W VCX1 3.1 18 6.5 0.7995 0.609948881 iYDL129W 0.49661213 0.833078556 0.692820013 VCX1 -- transport -- Calcium transport (H+/Ca2+ exchange) vacuolar membrane YML004C GLO1 2.8 16 6.5 0.7995 0.399474322 iYML004C 0.183732396 0.634669678 0.1836932 GLO1 -- amino acid metabolism -- Glyoxalase Iconverts hemimercaptal adduct of methylglyoxal and glutathione into S-D-lactoylglutathione YKL058W TOA2 2.7 16 6.5 0.7995 0.30774134 iYKL059C 0.243142617 0.166142558 0.415941317 TOA2 -- transcription -- RNA polymerase II transcription initiation factor TFIIA small subunit YDR533C YDR533C 2.6 15 6.5 0.7995 0.617916329 iYDR533C 0.61489719 0.77465219 0.85649754 YDR533C -- unknown -- unknown function YDL198C YHM1 2.5 14 6.5 0.7995 0.533141488 iYDL198C 0.197453172 0.637455772 0.282732294 YHM1 -- transport -- mitochondrial carrier (MCF) family that when overexpressed suppresses loss of Abf2p YLR008C YLR008C 2.4 13 6.5 0.7995 0.442800868 iYLR008C 0.115557319 0.342964293 0.187157589 YLR008C -- unknown -- unknown function YGR082W TOM20 2.2 13 6.5 0.7995 0.349342453 iYGR081C 0.21200467 0.586170865 0.345824598 TOM20 -- mitochondrial protein targeting -- Mitochondrial primary import receptor of outer membranehas tetratricopeptide (TPR) repeats YPR037C YPR037C 2.2 13 6.5 0.7995 0.467326739 0.077758578 YPR037C -- unknown -- similarity to Erv1p YBR206W YBR206W 2.1 12 6.5 0.7995 0.625106297 0.821149242 YBR206W -- unknown -- unknown functionquestionable ORF YLR222C YLR222C 2.1 12 6.5 0.7995 0.300532628 iYLR222C 0.519346768 0.606187773 0.62859074 "YLR222C -- unknown -- unknown function, overproduction causes chromosome instability and increased mitotic recombination, contains WD (WD-40) repeats" YOL022C YOL022C 1.8 10 6.5 0.7995 0.522786671 iYOL022C itG(GCC)O2 0.621294022 0.376265926 0.892014102 0.744857627 0.371611487 YOL022C -- unknown -- unknown function YOR272W YTM1 1.6 9 6.5 0.7995 0.255119825 iYOR271C SNR8 0.516565379 0.676619441 0.527615335 0.557557805 0.32016786 "YTM1 -- cytoskeleton (putative) -- Microtubule-associated protein essential for the G1/S transition, member of WD (WD-40) repeat family" YOL102C TPT1 1.3 8 6.5 0.7995 0.358460296 iYOL102C 0.393503697 0.506623879 0.276909442 TPT1 -- tRNA splicing -- NAD-dependent 2'-phosphotransferase in tRNA splicing YOR056C YOR056C 1.9 11 6.4 0.7957 1 0.407804086 iYOR056C 0.96074641 0.099680766 0.573534151 YOR056C -- unknown -- associates with the 26S proteasome YHR027C RPN1 4.6 27 6.4 0.7957 0.378787178 iYHR027C 0.414985127 0.257781325 0.284100992 RPN1 -- protein degradation -- Non-ATPase component of 26S proteasome complexrequired for degration of proteins of endoplasmic reticulum YBL091C MAP2 3.5 20 6.4 0.7957 0.360934722 iYBL091C 0.8525615 0.703216374 0.691269645 "MAP2 -- protein processing -- Methionine aminopeptidase isoform 2, cleaves N-terminal methionine" YJL143W TIM17 3.5 20 6.4 0.7957 0.046789437 iYJL144W 0.072525319 0.051494477 0.100551304 "TIM17 -- mitochondrial protein targeting -- Part of mitochondrial inner-membrane translocation channel with Tim23p, involved in import of proteins destined for mitochondrial matrix" YBL099W ATP1 3.4 20 6.4 0.7957 0.748684775 0.856743536 ATP1 -- ATP synthesis -- Alpha subunit of F1-ATP synthase YBR016W YBR016W 3.3 19 6.4 0.7957 0.150667693 iYBR015C 0.348277517 0.234956105 0.30782976 YBR016W -- unknown -- unknown function YIL142W CCT2 3.3 19 6.4 0.7957 0.702652582 iYIL143C 0.54870046 0.889213775 0.328708559 "CCT2 -- protein folding -- Component of Chaperonin-containing T-complex (TCP ring complex, TRiC)homologous to mouse CCT2" YDR212W TCP1 2.7 16 6.4 0.7957 0.579404372 iYDR211W 0.728025351 0.968378756 0.398754096 "TCP1 -- protein folding -- Component of chaperonin-containing T-complex (TCP ring complex, TRiC), homologous to mouse TCP1/CCT1" YIR044C YIR044C 2.7 16 6.4 0.7957 0.911466973 0.260175579 "YIR044C -- unknown -- Probable pseudogeneputative product has similarity to N-terminal region of Ybr302p, Ycr007p, and Ykl291p" YPR143W YPR143W 2.4 13 6.4 0.7957 0.01994023 0.02443841 YPR143W -- unknown -- unknown function YER062C HOR2 2.1 12 6.4 0.7957 0.671893156 iYER062C 0.413223122 0.794143744 0.568240413 HOR2 -- glycerol metabolism -- DL-glycerol phosphate phosphatase YGR029W ERV1 2.1 12 6.4 0.7957 0.577533381 iYGR028W 0.292642717 0.609626136 0.47317199 ERV1 -- mitochondrial biogenesis -- essential for mitochondrial biogenesis and cell viability YKR025W RPC37 2.1 12 6.4 0.7957 0.879104633 iYKR024C 0.516756351 0.480825008 0.578911795 "RPC37 -- transcription -- RNA polymerase III, C37 subunit" YML080W YML080W 1.9 11 6.4 0.7957 0.393992706 iYML081W 0.636728153 0.776184338 0.593443731 YML080W -- unknown -- weak similarity to Azospirillum brasilense nifR3 protein YMR269W YMR269W 1.9 11 6.4 0.7957 0.046415223 iYMR268C 0.105213645 0.052194733 0.093697195 "YMR269W -- unknown -- unknown function, rich in lysine and serine" YAL039C CYC3 1.8 11 6.4 0.7957 0.782985395 iYAL039C-0 iYAL039C-1 0.845290926 0.947763209 0.639213775 0.825532274 0.179010375 "CYC3 -- cytochrome c biosynthesis -- Holocytochrome-c synthase (cytochrome-c heme lyase), catalyzes covalent linkage of heme to apocytochrome c" YGR272C YGR272C 1.8 10 6.4 0.7957 0.482209914 iYGR272C 0.556892442 0.738089361 0.420727085 YGR272C -- unknown -- unknown function YJL125C GCD14 1.8 11 6.4 0.7957 0.191682482 iYJL125C 0.24063972 0.403825996 0.250081222 GCD14 -- protein synthesis -- translational repression of GCN4 mRNA YPR058W YMC1 1.8 11 6.4 0.7957 0.792884911 iYPR057W 0.423104751 0.923942538 0.714631002 YMC1 -- transport -- Member of mitochondrial carrier (MCF) family of membrane transporters YMR015C ERG5 2.1 12 6.3 0.793 1 0.919660862 iYMR015C 0.969506711 0.907961604 0.216818892 ERG5 -- sterol metabolism -- Cytochrome P450 YKR092C SRP40 1.8 11 6.3 0.793 1 0.670462679 iYKR092C-0 iYKR092C-1 0.980492887 0.721771985 0.30931167 0.346938776 0.712027103 SRP40 -- transcription (putative) -- Suppressor of rpc40 and rpb10 mutations YGR185C TYS1 4.5 26 6.3 0.793 0.408137882 iYGR185C 0.353307196 0.393376141 0.483228512 TYS1 -- protein synthesis -- Tyrosyl-tRNA synthetase YDL046W YDL046W 3.4 20 6.3 0.793 0.551799462 iYDL047W 0.364920987 0.646285392 0.388897841 YDL046W -- unknown -- unknown function YER057C HIG1 3.1 19 6.3 0.793 0.969688138 iYER057C 0.693018127 0.788028731 0.189091202 HIG1 -- heat shock response -- inhibits cell growthcontributes to cell death at high temperature YDR234W LYS4 2.7 16 6.3 0.793 0.478782807 iYDR233C 0.311246803 0.927824479 0.407356619 "LYS4 -- lysine biosynthesis -- Homoaconitate hydratase (homoaconitase), third step in lysine biosynthesis pathway, converts homoaconitate to homoisocitrate" YGL209W MIG2 2.7 16 6.3 0.793 0.53549276 iYGL210W 0.19928582 0.173455114 0.320003291 "MIG2 -- glucose repression -- Zinc-finger glucose repression of SUC2, has two tandem zinc-fingers" YMR264W CUE1 2.7 16 6.3 0.793 0.124131409 iYMR263W 0.510647557 0.528890662 0.197501747 "CUE1 -- protein degradation, ubiquitin-mediated -- recruits the soluble ubiquitin-conjugating enzyme Ubc7p to the membrane" YNL306W YNL306W 2.6 15 6.3 0.793 0.455676849 iYNL307C 0.270938314 0.712753085 0.167695219 "YNL306W -- protein synthesis -- Mitochondrial ribosomal small subunit (YmS18), has similarity to bacterial and chloroplast ribosomal protein S11" YDR091C RLI1 2.1 13 6.3 0.793 0.881142169 iYDR091C 0.42983511 0.968137453 0.879809631 "RLI1 -- unknown -- Putative ortholog of human Rnase L inhibitor (RLI) of interferon-regulated 2-5A pathway, putative ortholog of C. elegans Y39E4B.1, member of non-transporter group in the ATP-binding cassette (ABC) superfamily" YJR144W MGM101 2.1 12 6.3 0.793 0.842462338 iYJR143C 0.596376779 0.727113906 0.447936972 MGM101 -- mitochondrial genome maintenance -- Mitochondrial genome maintenance protein YOR176W HEM15 2 12 6.3 0.793 0.522577257 iYOR175C 0.106501143 0.78158234 0.335887715 "HEM15 -- heme biosynthesis -- Ferrochelatase (protoheme ferrolyase), last step in heme biosynthesis pathwaycatalyzes insertion of ferrous iron into protoporphyrin IX" YOR294W RRS1 1.8 11 6.3 0.793 0.373164317 iYOR293W 0.701444479 0.112246681 0.582984209 RRS1 -- ribosome biogenesis (putative) -- Regulator of ribosome synthesis YDR299W 1.7 10 6.3 0.793 0.743481554 iYDR298C 0.497548034 0.546049481 0.456493716 YML124C TUB3 3.5 21 6.2 0.7908 0.644218495 iYML124C 0.850335038 0.683288077 0.639832217 "TUB3 -- cytoskeleton -- Tubulin alpha-3 chain, non-essential" YMR072W ABF2 2.6 16 6.2 0.7908 0.748153225 iYMR071C 0.159902764 0.911778924 0.073842514 "ABF2 -- mitochondrial genome maintenance -- Abundant mitochondrial DNA-binding maintenance, transmission and recombination of mitochondrial genome, contains two HMG-box DNA-binding domains" YDL236W PHO13 2.5 15 6.2 0.7908 0.446718034 iYDL237W 0.510189996 0.69377494 0.794224409 PHO13 -- unknown -- 4-Nitrophenylphosphatase YBR052C YBR052C 2.4 14 6.2 0.7908 0.498143411 iYBR052C 0.455175463 0.658475669 0.456995607 "YBR052C -- unknown -- similarity to Ycp4p, S. pombe obr1, and E. coli trp repressor binding protein" YFR024C-A 2.4 14 6.2 0.7908 0.351255386 iYFR024C-A 0.27891212 0.333071279 0.485315243 YJL206C-A 2.2 13 6.2 0.7908 YLR297W YLR297W 2 12 6.2 0.7908 0.176567753 iYLR296W 0.321767948 0.367691788 0.398324202 YLR297W -- unknown -- unknown function YHR197W YHR197W 1.9 12 6.2 0.7908 0.331082053 iYHR196W 0.615932516 0.725104822 0.643704122 YHR197W -- unknown -- unknown function YJR101W YJR101W 1.8 11 6.2 0.7908 0.732068112 iYJR100C itL(UAG)J 0.694910399 0.565460757 0.752274541 0.649109015 0.506284241 YJR101W -- unknown -- respiratory growthmay have a role in stress resistance and pseudohyphal growth YML093W YML093W 1.6 10 6.2 0.7908 0.13115017 iYML094W 0.575387655 0.138645224 0.464792137 YML093W -- unknown -- unknown function YPL183C YPL183C 1.3 8 6.2 0.7908 0.663449944 iYPL183C 0.428272036 0.654916512 0.516422082 "YPL183C -- unknown -- unknown function, has WD (WD-40) repeats" YDR324C YDR324C 1.7 10 6.1 0.7874 1 0.924212222 iYDR324C 0.98405641 0.321368073 0.604979053 YDR324C -- unknown -- multiple WD40 repeats YIL041W YIL041W 4.5 27 6.1 0.7874 0.30554054 iYIL042C 0.073313307 0.487689584 0.252238445 YIL041W -- unknown -- unknown function YBL040C ERD2 3.7 23 6.1 0.7874 0.431657121 iYBL040C 0.55338365 0.573767847 0.967417104 ERD2 -- ER protein retention -- receptor-mediated retrieval of lumenal ER protein from the secretory pathway YDR129C SAC6 3.5 21 6.1 0.7874 0.456039341 iYDR129C 0.310884137 0.66991621 0.409775364 "SAC6 -- cytoskeleton -- Actin filament bundling protein, fimbrinessential for polarized secretion" YGL070C RPB9 3.3 20 6.1 0.7874 0.746119394 iYGL070C 0.306721837 0.660981157 0.385899814 "RPB9 -- transcription -- RNA polymerase II, non-essential subunit, not shared" YDR424C DYN2 3.1 19 6.1 0.7874 iYDR424C 0.098426469 0.105590062 DYN2 -- cytoskeleton -- Cytoplasmic dynein light chain YGR267C FOL2 3 19 6.1 0.7874 0.60112111 iYGR267C 0.238672976 0.896648045 0.496329757 "FOL2 -- folate biosynthesis -- GTP cyclohydrolase I, catalyzes synthesis of D-erythro-7,8-dihydroneopterintriphosphate from GTP" YMR238W DFG5 3 18 6.1 0.7874 0.295913216 iYMR237W 0.399787484 0.307578376 0.485820174 "DFG5 -- pseudohyphal growth -- filamentous growth, cell polarity, and cellular elongation" YGL040C HEM2 2.7 16 6.1 0.7874 0.326843941 iYGL040C-0 iYGL040C-1 0.361018348 0.619067798 0.728557505 0.404044473 0.673630717 "HEM2 -- heme biosynthesis -- Porphobilinogen synthase (delta-aminolevulinic acid dehydratase), second step in heme biosynthesis pathway" YER086W ILV1 2.6 16 6.1 0.7874 0.40820695 iYER085C 0.38118724 0.681051867 0.329096828 "ILV1 -- isoleucine and valine biosynthesis -- Serine and threonine dehydratase (anabolic), first step in isoleucine biosynthesis pathway" YML085C TUB1 2.6 15 6.1 0.7874 0.515040241 iYML085C 0.562090283 0.842754875 0.569403371 "TUB1 -- cytoskeleton -- Tubulin alpha-1 chain, required for mitosis and karyogamy" YDL040C NAT1 2 13 6.1 0.7874 0.770398636 iYDL040C 0.436968146 0.803420182 0.370807128 "NAT1 -- protein processing -- N-acetyltransferase subunit, mating functions are reduced in mutants due to derepression of silent mating type loci" YDR384C YDR384C 2 12 6.1 0.7874 0.277147142 iYDR384C 0.257096797 0.56485659 0.341614907 "YDR384C -- unknown -- unknown function, has strong similarity to Ynr002p and Ycr010p" YHR136C SPL2 2 12 6.1 0.7874 0.340335662 iYHR136C 0.092128744 0.330974843 0.078066914 "SPL2 -- cell cycle -- Putative inhibitor of Pho80p-Pho85p cyclin-dependent protein kinase, may block phosphorylation of novel factors other than Pho4p" YNL016W PUB1 2 13 6.1 0.7874 0.237780489 0.31485659 "PUB1 -- mRNA processing -- Major polyadenylated RNA-binding nucleus and cytoplasm, contains 3 RNA recognition (RRM) domains and 3 gln-asn-rich domains" YKL021C MAK11 1.8 11 6.1 0.7874 0.181292348 iYKL021C 0.583360034 0.466806316 0.374249343 MAK11 -- dsRNA virus propagation -- essential for replication of M double-stranded RNA (dsRNA) virusmember of WD (WD-40) repeat family YBR268W MRPL37 1.7 10 6.1 0.7874 0.251093325 iYBR267W 0.720597844 0.744292974 0.967169476 MRPL37 -- protein synthesis -- Mitochondrial ribosomal large subunit YDL147W RPN5 4.6 28 6 0.7835 0.578947223 iYDL148C 0.34709714 0.497136404 0.437928531 RPN5 -- protein degradation -- Non-ATPase subunit of 26S proteasome complex YNL079C TPM1 4.4 27 6 0.7835 0.023524495 iYNL079C 0.082929148 0.02014295 0.01161775 "TPM1 -- cytoskeleton -- Tropomyosin, coiled-coil protein localized to actin cables" YDR238C SEC26 3.1 19 6 0.7835 0.554424765 iYDR238C 0.360992292 0.396310023 0.704309657 SEC26 -- secretion -- Coatomer (COPI) complex beta chain (beta-COP) of secretory pathway vesiclesrequired for retrograde transport from Golgi to endoplasmic reticulum YPL235W RVB2 3.1 20 6 0.7835 0.22451713 iYPL236C 0.415252046 0.362265064 0.742921675 RVB2 -- unknown -- Putative 5' to 3' DNA helicase involved in ribosomal RNA processing YGL157W YGL157W 3 19 6 0.7835 0.288970682 iYGL158W 0.222006693 0.722029523 0.315164221 YGL157W -- unknown -- weak similarity to tomato dihydroflavonol 4-reductase YLR034C SMF3 3 19 6 0.7835 0.573923853 iYLR034C 0.230228738 0.852625635 0.544721468 "SMF3 -- trnasport (putative) -- Possible metal transporter, has similarity to Smf1p and Smf2p" YGL173C KEM1 2.9 18 6 0.7835 0.465866791 iYGL173C 0.452494843 0.47725796 0.783415342 "KEM1 -- mRNBA decay -- Nuclease with 5'-3' exonuclease activity for single-stranded RNA and DNA, primary role is to degrade decapped mRNA" YDR019C GCV1 2.8 17 6 0.7835 0.783404805 iYDR019C 0.49390349 0.758570622 0.425937749 "GCV1 -- amino acid metabolism -- Glycine decarboxylase T subunit (glycine cleavage T protein), functions in the pathway for glycine degradation" YGR055W MUP1 2.8 17 6 0.7835 0.778593928 iYGR054W 0.583627354 0.796807662 0.714668616 MUP1 -- transport -- High-affinity methionine permease YGL198W YGL198W 2.7 17 6 0.7835 0.623181286 0.944606888 YGL198W -- unknown -- similarity to NADH-ubiquinone oxidoreductase chain 2 of C. elegans YOR204W DED1 2.6 16 6 0.7835 0.719858729 0.593055108 DED1 -- RNA processing -- ATP-dependent RNA helicase of DEAD box family involved in protein synthesis YIL157C YIL157C 2.5 15 6 0.7835 0.287833755 iYIL157C 0.142493844 0.69077594 0.237721678 YIL157C -- unknown -- unknown function YKR026C GCN3 2.4 14 6 0.7835 0.746080598 iYKR026C YKRCdelta9 0.681586709 0.478148878 0.691187361 0.861612131 0.361374193 "GCN3 -- protein synthesis -- Translation initiation factor eIF2B (guanine nucleotide exchange factor), 34 kDa (alpha) subunit" YGR095C RRP46 2.2 14 6 0.7835 iYGR095C 0.584555237 0.330529125 RRP46 -- rRNA processing -- component of exosome 3'-5' exoribonuclease complex involved in involved 3'end processing of multiple small RNA species YDR084C YDR084C 1.9 11 6 0.7835 0.447507281 iYDR084C 0.483841412 0.602161813 0.455067837 YDR084C -- unknown -- unknown function YDR280W RRP45 1.9 12 6 0.7835 0.328884959 iYDR279W 0.5443326 0.538522013 0.535514765 RRP45 -- rRNA processing -- component of exosome 3'-5' exoribonuclease complex involved in involved in 3'-end processing of multiple small RNA species YDL121C YDL121C 1.8 11 6 0.7835 0.77827393 iYDL121C 0.587989388 0.472465887 0.862945493 YDL121C -- unknown -- unknown function YOL010W RCL1 1.8 11 6 0.7835 0.699252351 iYOL011W 0.299425067 0.787230331 0.26217079 RCL1 -- unknown -- Putative RNA 3'-terminal phosphate cyclase YEL007W YEL007W 1.7 10 6 0.7835 0.356312478 iYEL008W 0.969046063 0.210483008 0.134665367 YEL007W -- unknown -- unknown functionhas similarity to Yhr177p YFL017C GNA1 1.7 10 6 0.7835 0.655923869 iYFL017C 0.247979458 0.705204641 0.055335968 GNA1 -- UDP-N-acetylglucosamine biosynthesis -- Phosphoglucosamine acetyltransferase YBL041W PRE7 4 25 5.9 0.7811 0.472550749 iYBL042C 0.376613043 0.884390685 0.326939411 PRE7 -- protein degradation -- Proteasome subunit beta6_sc YGL122C NAB2 3.1 20 5.9 0.7811 0.613836204 iYGL122C 0.682217952 0.475738228 0.696408619 "NAB2 -- mRNA processing -- Nuclear poly(A)-binding protein, required for proper polyadenylation of pre-mRNA and for mRNA export" YBR090C-A 3 19 5.9 0.7811 YNL312W RFA2 3 19 5.9 0.7811 0.356535006 iYNL313C 0.397146539 0.239430468 0.448505523 "RFA2 -- DNA replication -- DNA replication factor A, 36K subunitphosphorylated at the G1/S transition and dephosphorylated at mitosis" YNL189W SRP1 2.6 16 5.9 0.7811 0.844103218 iYNL190W 0.824111202 0.89998253 0.668868837 "SRP1 -- nuclear protein targeting -- Karyopherin-alpha or importin, involved in nuclear import, nuclear structure, chromosome segregation, and cell cycle" YDR272W GLO2 2.1 14 5.9 0.7811 0.637643212 iYDR271C 0.518442116 0.852201258 0.311757512 GLO2 -- methylglyoxal resistance -- Glyoxalase-II YIL118W RHO3 2 13 5.9 0.7811 0.402205912 iYIL119C-0 iYIL119C-1 0.40958394 0.248512242 0.492852502 0.324968507 0.586835525 "RHO3 -- cytoskeleton -- GTP-binding control of actin cytoskeleton and exocytosis, member of rho family in the ras superfamily" YPR100W YPR100W 2 13 5.9 0.7811 0.217419459 YPR100W -- unknown -- unknown function YJL097W YJL097W 1.8 11 5.9 0.7811 0.976606767 iYJL098W 0.849750812 0.784947971 YJL097W -- unknown -- Essential unknown function YLR375W STP3 1.8 11 5.9 0.7811 0.393169854 0.65545809 "STP3 -- tRNA splicing -- strong similarity to Stp1p, which is involved in tRNA splicing and branched-chain amino acid uptake" YNL062C GCD10 1.6 10 5.9 0.7811 0.264044034 iYNL062C 0.368487236 0.317901235 GCD10 -- protein synthesis -- RNA-binding subunit of initiation factor eIF3 YNL132W YNL132W 1.6 10 5.9 0.7811 0.321676079 iYNL133C itF(GAA)N 0.522228475 0.062028022 0.569818152 0.475910409 0.067758329 YNL132W -- unknown -- unknown function YKL065C YET1 4.4 28 5.8 0.7777 0.476108616 iYKL065C 0.221918966 0.400724101 0.270988268 YET1 -- unknown -- Transmembrane endoplasmic reticulum YFR053C HXK1 3.7 23 5.8 0.7777 0.529418846 iYFR053C-0 iYFR053C-1 0.327337239 0.371360174 0.866796621 0.459452234 0.156838856 "HXK1 -- glycolysis -- Hexokinase I, converts hexoses to hexose phosphates in glycolysisrepressed by glucose" YKL210W UBA1 3.4 21 5.8 0.7777 0.489480679 iYKL211C SNR64 0.031634378 0.072374343 0.729294231 0.024261772 0.003910615 "UBA1 -- protein degradation, ubiquitin-mediated -- Ubiquitin-activating (E1) enzyme" YBR302C COS2 2.9 19 5.8 0.7777 0.931432918 YCLWTy5-1A 0.990963 0.560355468 0.43955276 COS2 -- unknown -- Member of COS family of subtelomerically-encoded proteins YBR014C YBR014C 2.5 15 5.8 0.7777 0.692993505 iYBR014C 0.78928572 0.804245865 0.689116003 YBR014C -- unknown -- similarity to glutaredoxin YPR148C YPR148C 2.5 16 5.8 0.7777 0.195220784 iYPR148C-0 iYPR148C-1 0.636746785 0.785354344 0.178914253 0.657232173 0.343466108 YPR148C -- unknown -- unknown function YAL007C ERP2 2.2 14 5.8 0.7777 0.35441453 iYAL007C YALCdelta2 0.367046351 0.717986077 0.823724668 0.615041929 0.463905898 "ERP2 -- membrane trafficking; secretion (putative) -- similarity to COPII-coated vesicle proteins Emp24p and Erv25p, forms an Erp1p-Erp2p-Emp24p-Erv25p heteromeric complex" YER174C GRX4 2 13 5.8 0.7777 0.859266636 iYER174C 0.215546307 0.989916915 0.091500507 "GRX4 -- oxidative stress response -- Glutaredoxin, has similarity to Grx3p and Grx5p" YCL059C KRR1 1.9 12 5.8 0.7777 0.323075946 iYCL059C 0.572319733 0.664918932 0.227420403 KRR1 -- unknown -- essential for cell division and spore germination YJL079C PRY1 1.9 12 5.8 0.7777 0.100511438 iYJL079C 0.631524344 0.143437297 0.147626071 "PRY1 -- unknown -- similarity to plant pathenogenesis-related proteins, may have a role in mating efficiency" YPL043W NOP4 1.9 13 5.8 0.7777 0.208559305 0.15188434 "NOP4 -- rRNA processing -- Nucleolar ribosome biogenesis, has 3 canonical RNA recognition (RRM) domains and one degenerate RNA recognition (RRM) domain" YPR166C MRP2 1.9 12 5.8 0.7777 0.601731638 iYPR166C 0.118156635 0.691296281 0.245543277 MRP2 -- protein synthesis -- Mitochondrial ribosomal small subunit YDR119W YDR119W 1.7 11 5.8 0.7777 0.323421625 iYDR118W 0.298907393 0.736819904 0.202336872 YDR119W -- unknown -- Member of major facilitator superfamily (MFS) multidrug-resistance (MFS-MDR) protein family YDR302W GPI11 1.7 11 5.8 0.7777 0.441349786 iYDR301W 0.374938175 0.618201267 0.319688109 "GPI11 -- unknown -- glycosylphosphatidylinositol (GPI) biosynthesis, with similarity to GPI-anchor biosynthesis PIG-F" YPL127C HHO1 1.6 10 5.8 0.7777 0.470677392 iYPL127C 0.044362566 0.234976204 0.111083683 HHO1 -- chromatin structure -- Histone H1 YHR013C ARD1 1.5 9 5.8 0.7777 0.355252387 iYHR013C 0.409046184 0.604743083 0.447851153 "ARD1 -- protein processing -- N-acetyltransferase subunit, functions in a complex with Nat1prequired for transcriptional silencing at telomeres and transcriptional repression of silent HML locus" YKL029C MAE1 1.5 9 5.8 0.7777 0.835422289 iYKL029C 0.865540771 0.465356107 0.405267358 "MAE1 -- pyruvate metabolism -- Mitochondrial malate dehydrogenase (NADP+, oxaloacetate-decarboxylating)" YLR216C CPR6 5.3 34 5.7 0.7748 0.334804081 0.562436634 "CPR6 -- protein folding (putative) -- Cyclophilin (peptidylprolyl cis-trans isomerase or PPIase), interacts with Hsp82p, homolog of mammalian cyclophilin Cyp40" YJL174W KRE9 4 26 5.7 0.7748 0.500074619 iYJL175W 0.104798863 0.667579762 0.082202713 "KRE9 -- cell wall biogenesis -- Glyco cell surface beta-1,6-glucan assemblymutants are resistant to K1 killer toxin" YOR151C RPB2 3.9 26 5.7 0.7748 0.492209352 iYOR151C 0.444870957 0.792700612 0.57576849 "RPB2 -- transcription -- RNA polymerase II, second-largest subunit" YFR009W GCN20 2.8 18 5.7 0.7748 0.666526553 iYFR008W iYFRCdelta8 0.454625645 0.454265825 0.90758943 0.204560103 "GCN20 -- protein synthesis -- Component of a protein complex required for activation of Gcn2p protein kinase in response to amino acid starvation, member of non-transporter group within the ATP-binding cassette (ABC) superfamily" YGR132C PHB1 2.8 18 5.7 0.7748 0.490851091 iYGR132C 0.253742934 0.789105571 0.197851153 "PHB1 -- antiproliferative protein -- Prohibitin, involved in determination of replicative lifespanmember of prohibitin complex with Phb2p" YPR098C YPR098C 2.8 19 5.7 0.7748 0.679617938 iYPR098C 0.392927148 0.425738501 YPR098C -- unknown -- unknown function YBR262C YBR262C 2.5 16 5.7 0.7748 0.101189317 0.207821229 YBR262C -- unknown -- unknown function YOR209C NPT1 2.5 16 5.7 0.7748 0.217125958 iYOR209C 0.169128015 0.385916855 0.133122157 "NPT1 -- NAD biosynthesis -- Nicotinate phosphoribosyltransferase (NAPRTase), first step in the Preiss-Handler pathway leading to the synthesis of NAD" YJL012C PHM3 2.1 14 5.7 0.7748 0.60053904 iYJL012C 0.445911655 0.601998066 0.769193935 PHM3 -- unknown -- Putative polyphosphate synthetase YNR024W YNR024W 1.9 12 5.7 0.7748 0.236076943 iYNR023W 0.350934848 0.512491265 0.538632436 YNR024W -- unknown -- unknown function YOR164C YOR164C 1.8 12 5.7 0.7748 0.720332229 iYOR164C 0.480636519 0.849090759 0.544063194 YOR164C -- unknown -- unknown function YIL127C YIL127C 1.7 11 5.7 0.7748 0.238370778 iYIL127C 0.157529047 0.410650983 0.041300315 YIL127C -- unknown -- unknown function YKL120W OAC1 1.7 11 5.7 0.7748 0.63252673 iYKL121W 0.307237177 0.667198723 0.280443162 "OAC1 -- transport -- Mitochondrial oxaloacetate transporter, member of mitochondrial carrier (MCF) family" YLR221C YLR221C 1.7 11 5.7 0.7748 0.143487596 iYLR221C 0.201887936 0.145560767 0.370310916 YLR221C -- unknown -- unknown function YLR243W YLR243W 1.7 11 5.7 0.7748 0.151977432 iYLR242C 0.182361815 0.446640316 0.167627533 YLR243W -- unknown -- unknown function YOL030W YOL030W 5.1 33 5.6 0.7714 0.473126113 iYOL031C 0.224688506 0.343342878 YOL030W -- unknown -- similarity to Gas1p YDR513W TTR1 3.4 22 5.6 0.7714 0.282433142 0.291572672 "TTR1 -- electron carrier -- Glutaredoxin (thioltransferase, glutathione reductase)" YBR068C BAP2 3.1 21 5.6 0.7714 0.569973684 iYBR068C 0.653665631 0.386706461 0.858514157 "BAP2 -- transport -- Branched-chain amino acid permease specific for leucine, valine, and isoleucine" YGR038W ORM1 2.8 19 5.6 0.7714 0.835838894 iYGR037C 0.446577305 0.945536578 0.620020964 ORM1 -- unknown -- unknown function YBL102W SFT2 2.6 17 5.6 0.7714 0.791048357 iYBL103C 0.455717456 0.919996751 0.811260224 "SFT2 -- unknown -- Membrane ER to Golgi transport, can suppress temperature-sensitive mutants of SED5 when overexpressed" YHR135C YCK1 2.6 17 5.6 0.7714 0.368666158 iYHR135C 0.335119828 0.386982638 0.201417983 YCK1 -- unknown -- Casein kinase I isoform YKL024C URA6 2.6 17 5.6 0.7714 0.900538922 iYKL024C 0.386514489 0.966374269 0.207138253 URA6 -- pyrimidine metabolism -- Uridine-monophosphate kinase (uridylate kinase)converts ATP and UMP to ADP and UDP YER042W MXR1 2.4 16 5.6 0.7714 0.812627804 iYER041W 0.282390115 0.931530214 0.079938695 MXR1 -- oxidative stress response -- Peptide methionine sulfoxide reductase involved in cellular antioxidation YGR195W SKI6 2.4 16 5.6 0.7714 0.674516378 iYGR194C 0.432163898 0.852302977 0.501520784 "SKI6 -- rRNA processing -- Component of exosome 3'-5' exoribonuclease complex involved in 3' processing of ribosomal 5.8S rRNA, of snoRNAs and of U4 snRNA, and in degradation of poly(A)- mRNAs, confers antiviral activity by repressing replication of double-stranded RNA viruses" YDR211W GCD6 2.2 15 5.6 0.7714 0.641933008 YDRCTy1-2D iYDRCTy1-2 0.157914951 0.78575864 0.867996808 0.136530398 0.457562668 "GCD6 -- protein synthesis -- Translation initiation factor eIF2B (guanine nucleotide exchange factor), 81 kDa (beta) subunit" YBR105C VID24 2 13 5.6 0.7714 0.50922778 iYBR105C 0.647673062 0.783878691 0.453616087 VID24 -- vacuolar protein targeting -- vacuolar import and degradation of Fbp1p YPR138C MEP3 1.8 12 5.6 0.7714 0.119104114 iYPR138C 0.127271216 0.190541412 0.188836009 MEP3 -- transport -- Ammonia permease of high capacity and low affinity YJL212C OPT1 1.7 11 5.6 0.7714 0.386930788 iYJL212C 0.126679618 0.661630929 OPT1 -- unknown -- member of oligopeptide transporter (OPT) family YER001W MNN1 1.6 11 5.6 0.7714 0.64780127 iYEL001C CEN5 0.488654179 0.770569932 0.39586354 0.516711158 0.280460296 "MNN1 -- protein glycosylation -- Alpha-1,3-mannosyltransferase, required for complex glycosylation of both N- and O-oligosaccharides" YLL011W SOF1 1.6 11 5.6 0.7714 0.329826673 iYLL012W 0.680961824 0.426643627 0.633917551 SOF1 -- rRNA processing -- associated with U3 small nucleolar RNA (snoRNA) and involved in 18S pre-rRNA maturationhas 7 WD (WD-40) repeats YBR267W YBR267W 1.3 9 5.6 0.7714 0.351866454 0.536160865 "YBR267W -- unknown -- unknown function, has a single C2H2-type zinc finger" YGR128C YGR128C 1.2 8 5.6 0.7714 0.701679805 iYGR128C 0.440337556 0.97669593 0.604097766 YGR128C -- unknown -- similarity to Haemophilus glutamate-ammonia-ligase adenylyltransferase (glnE) PIR YIL075C RPN2 3.7 25 5.5 0.7679 0.714133685 iYIL075C 0.664225838 0.626100551 0.90933759 "RPN2 -- tRNA processing -- Non-ATPase component of 26S proteasome complex, has an effect on the tRNA splicing system" YNR001C CIT1 3.7 25 5.5 0.7679 iYNR001C itP(AGG)N 0.763498366 0.670278212 0.724820431 0.668874701 "CIT1 -- TCA cycle -- Citrate synthase, mitochondrial, converts acetyl-CoA and oxaloacetate into citrate plus CoA" YOR027W STI1 3.6 24 5.5 0.7679 0.451444312 iYOR026W 0.389873733 0.213225017 0.170151636 "STI1 -- protein folding -- Stress-induced optimal growth at high and low temperature, has tetratricopeptide (TPR) repeats" YBR062C YBR062C 3.4 23 5.5 0.7679 0.686917439 iYBR062C 0.313566721 0.7436634 0.577414206 YBR062C -- unknown -- unknown function YGL011C SCL1 3.1 21 5.5 0.7679 0.700987072 iYGL011C 0.499335276 0.947964884 0.651305189 "SCL1 -- protein degradation -- Proteasome subunit alpha1_sc(YC7alpha/Y8, protease yscE subunit 7)" YNL052W COX5A 3.1 21 5.5 0.7679 0.581638395 iYNL053W 0.303315533 0.900089971 0.74240858 COX5A -- oxidative phosphorylation -- Cytochrome-c oxidase subunit Va YMR286W MRPL33 2.9 20 5.5 0.7679 0.493209966 iYMR285C 0.653610973 0.212609737 0.529992594 MRPL33 -- protein synthesis -- Mitochondrial ribosomal large subunit (YmL33E. coli L30) YDR368W YPR1 2.6 17 5.5 0.7679 0.651094143 iYDR367W 0.424779605 0.984596967 0.641122852 YPR1 -- unknown -- similarity to members of aldo/keto reductase family YDR449C YDR449C 2.4 15 5.5 0.7679 0.966164805 iYDR449C 0.983170496 0.989674921 0.542631282 "YDR449C -- unknown -- unknown function, localized to the nucleus" YER022W SRB4 2 14 5.5 0.7679 0.305381932 iYER021W 0.585757947 0.776616121 0.457846004 SRB4 -- transcription -- Component of RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex YDL174C DLD1 1.9 13 5.5 0.7679 0.417173159 iYDL174C 0.190036226 0.334119497 0.188271605 "DLD1 -- pyruvate metabolism -- D-lactate dehydrogenase (cytochrome), (D-lactate ferricytochrome c oxidoreductase, D-LCR), mitochondrial" YNR037C YNR037C 1.9 12 5.5 0.7679 0.505915278 iYNR037C 0.065828161 0.536658073 0.341961143 "YNR037C -- unknown -- Putative mitochondrial ribosomal small subunit, has similarity to prokaryotic ribosomal protein S19" YOR323C PRO2 1.8 12 5.5 0.7679 0.099734554 iYOR323C 0.570360171 0.451176281 0.186190783 "PRO2 -- proline biosynthesis -- Gamma-glutamyl phosphate reductase (phosphoglutamate dehydrogenase), proline biosynthetic enzyme" YGL232W YGL232W 1.6 11 5.5 0.7679 0.511539587 iYGL233W 0.569169908 0.750907478 0.132596416 YGL232W -- unknown -- similarity to dihydropteroate synthase YGR108W CLB1 1.6 11 5.5 0.7679 0.508843982 iYGR107W 0.324995953 0.903214535 CLB1 -- cell cycle -- G2/M-phase-specific cyclin YPL217C BMS1 1.5 10 5.5 0.7679 0.389205911 iYPL217C 0.517485328 0.168763103 0.635314996 BMS1 -- unknown -- bud site selection in diploidsinteracts genetically with BMH1 YGR286C BIO2 1.3 9 5.5 0.7679 0.330695319 iYGR286C-0 iYGR286C-1 0.16424454 0.109862845 0.647086991 0.545379742 0.167379205 "BIO2 -- biotin biosynthesis -- Biotin synthetase, catalyzes insertion of a sulfur atom between two carbon atoms of dethiobiotin in the last step of biotin synthesis pathway" YOR051C YOR051C 1.3 9 5.5 0.7679 0.498834311 iYOR051C 0.448641983 0.73774283 0.302061495 YOR051C -- unknown -- Nuclear unknown function YCR104W PAU3 3.6 25 5.4 0.7639 0.938802808 iYCR103C 0.944820843 0.640186916 0.759135275 PAU3 -- unknown -- Member of seripauperin (PAU) family YFL010C YFL010C 3.5 24 5.4 0.7639 0.307058938 iYFL010C 0.611762802 0.468815514 0.669221492 YFL010C -- unknown -- unknown function YFL062W COS4 3 21 5.4 0.7639 0.945875106 iYFL063W 0.996910256 0.396789546 0.146548177 COS4 -- unknown -- Member of COS family of subtelomerically-encoded proteins YDR007W TRP1 2.6 18 5.4 0.7639 0.391735 iYDR006C 0.55090115 0.302476755 0.346454787 "TRP1 -- tryptophan biosynthesis -- Phosphoribosylanthranilate isomerase, catalyzes the third step in the tryptophan biosynthesis pathway" YPL004C YPL004C 2.6 18 5.4 0.7639 0.611847049 iYPL004C 0.349786946 0.605865292 0.297344514 YPL004C -- unknown -- weak similarity to tropomyosin YKL211C TRP3 2.5 17 5.4 0.7639 0.674336398 iYKL211C SNR64 0.031634378 0.072374343 0.927306693 0.024261772 0.003910615 TRP3 -- tryptophan biosynthesis -- Anthranilate synthase YML072C YML072C 2.5 17 5.4 0.7639 0.764899784 iYML072C 0.76973251 0.286601597 0.877334397 YML072C -- unknown -- unknown function YGL077C HNM1 2.1 15 5.4 0.7639 0.552326053 iYGL077C 0.471822934 0.55373437 0.547131808 "HNM1 -- transport -- Choline permease, member of amino acid permease family of membrane transporters" YOR222W YOR222W 2 13 5.4 0.7639 0.675941973 iYOR221C 0.451293249 0.591443764 0.509421542 "YOR222W -- unknown -- similarity to mitochondrial ADP/ATP carrier proteins, member of mitochondrial carrier family (MCF) of membrane transporters" YDR098C GRX3 1.9 13 5.4 0.7639 0.238336465 iYDR098C itQ(UUG)D2 0.616702421 0.440722839 0.296648045 0.355421561 0.471827614 "GRX3 -- oxidative stress response -- Glutaredoxin, has similarity to Grx4p and Grx5p" YER110C KAP123 1.9 13 5.4 0.7639 0.643557424 iYER110C 0.590599701 0.810614525 0.177462289 KAP123 -- nuclear protein targeting -- Karyopherin-beta involved in nuclear import of ribosomal proteins YIL083C YIL083C 1.8 12 5.4 0.7639 0.444437836 iYIL083C YILWTy3-1A 0.288970845 0.024954553 0.926332034 0.702873105 0.03056664 YIL083C -- unknown -- unknown function YKL128C PMU1 1.8 12 5.4 0.7639 0.796893076 iYKL128C itK(CUU)K 0.853569694 0.68225225 0.919742411 0.932748899 0.803721174 PMU1 -- unknown -- Possible phosphomutasemulticopy suppressor of temperature sensitivity of tps2 YOR091W YOR091W 1.7 12 5.4 0.7639 0.149076203 iYOR090C 0.452177831 0.386592179 0.334876297 YOR091W -- unknown -- unknown function YDL038C YDL038C 1.6 11 5.4 0.7639 0.525594785 iYDL038C 0.191206311 0.509720094 0.607212476 YDL038C -- unknown -- unknown function YDR410C STE14 1.6 11 5.4 0.7639 0.752256785 iYDR410C 0.565416661 0.934090348 0.611679662 STE14 -- mating -- Farnesyl cysteine YKL008C LAC1 1.5 10 5.4 0.7639 0.896102419 iYKL008C 0.767560673 0.988962295 0.790191175 LAC1 -- aging -- Protein required with Lag1p for ER-to-Golgi transport of GPI-anchored proteins YMR239C RNT1 1.3 9 5.4 0.7639 0.361302652 iYMR239C 0.535097781 0.443814844 0.561342272 "RNT1 -- rRNA processing -- Double-strand-specific ribonuclease required for rRNA processing, homolog of E. coli RNase III" YHR144C DCD1 1.2 9 5.4 0.7639 0.680322809 iYHR144C 0.350817156 0.953253707 0.567423096 DCD1 -- pyrimidine metabolism -- Deoxycytidylate deaminase YNR003C RPC34 1 7 5.4 0.7639 0.555770728 iYNR003C 0.628936417 0.920240416 0.763564003 "RPC34 -- transcription -- RNA polymerase III, essential subunit, not shared" YLR378C SEC61 3.4 24 5.3 0.7596 0.519010211 0.774122807 "SEC61 -- secretion -- Component of Sec61p-Sss1p-Sbh1p complex, involved in protein translocation into the endoplasmic reticulum" YDL145C COP1 2.8 20 5.3 0.7596 0.497575425 iYDL145C 0.734071142 0.416687238 0.854427171 "COP1 -- secretion -- Coatomer (COPI) complex alpha chain (alpha-COP) of secretory pathway vesicles required for retrograde Golgi to endoplasmic reticulum transport, member of WD (WD-40) repeat family" YNL100W YNL100W 2.6 18 5.3 0.7596 0.160320223 iYNL101W 0.119107191 0.353312051 0.111572227 YNL100W -- unknown -- unknown function YFL028C CAF16 2.5 17 5.3 0.7596 0.552482877 iYFL028C 0.235380595 0.79584996 0.209600697 "CAF16 -- transport -- associates with Ccr4p, member of non-transporter group of ATP-binding cassette (ABC) superfamily" YAL049C YAL049C 2.4 16 5.3 0.7596 0.747196822 iYAL049C 0.470616609 0.82975397 0.653929438 YAL049C -- unknown -- unknown function YDL165W CDC36 2.2 15 5.3 0.7596 iYDL166C 0.626510243 0.590899182 CDC36 -- transcription -- Nuclear negatively affects basal transcription from many promoterspart of CCR4 transcription complex YPR060C ARO7 2.2 16 5.3 0.7596 0.361050389 iYPR060C 0.733723905 0.649021663 0.545240416 ARO7 -- aromatic amino acid biosynthesis -- Chorismate mutaserequired for the synthesis of both phenylalanine and tyrosine YDR502C SAM2 2.1 15 5.3 0.7596 0.865749306 iYDR502C 0.65897685 0.954085411 0.240452856 SAM2 -- methionine biosynthesis -- S-adenosylmethionine synthetase 2 YGL242C YGL242C 2.1 15 5.3 0.7596 0.22172607 iYGL242C 0.067101748 0.353163828 0.034591195 YGL242C -- unknown -- similarity to ankyrin and coiled-coil proteins YIL027C YIL027C 2.1 15 5.3 0.7596 0.714501755 iYIL027C 0.158428849 0.711492418 0.405892735 "YIL027C -- unknown -- unknown function, has a hydrophobic domain" YJR072C YJR072C 2.1 15 5.3 0.7596 0.169733476 iYJR072C 0.567960952 0.515630281 0.289424861 YJR072C -- unknown -- unknown function YNL032W SIW14 2.1 15 5.3 0.7596 0.581188279 iYNL033W 0.342042225 0.863300889 0.385830659 SIW14 -- cell cycle -- Protein tyrosine phosphatase (PTPase) involved in nutritional control of cell cycle YDR046C BAP3 2 14 5.3 0.7596 0.567410471 iYDR046C 0.585744249 0.235130761 0.776104666 "BAP3 -- transport -- Branched chain amino acid permease, valine transporter" YEL037C RAD23 1.9 13 5.3 0.7596 0.619550215 iYEL037C 0.641219162 0.211013567 0.571347907 "RAD23 -- DNA repair, nucleotide excision -- Nucleotide excision repair ubiquitin-like domain, ortholog of human XP-C complementing genes hHR23B and hHR23A" YKR093W PTR2 1.9 13 5.3 0.7596 0.710849272 iYKR092C-0 iYKR092C-1 0.980492887 0.721771985 0.694322406 0.346938776 0.712027103 PTR2 -- transport -- Peptide permease nitrogen-repressible transporter of di- and tri-peptides and member of proton-dependent oligopeptide transporter family YOR116C RPO31 1.8 12 5.3 0.7596 0.268702721 iYOR116C 0.34392447 0.312762281 0.437751995 "RPO31 -- transcription -- RNA polymerase III, largest subunit" YLR022C YLR022C 1.7 11 5.3 0.7596 0.531736314 iYLR022C 0.475842109 0.56191014 0.257815018 YLR022C -- unknown -- unknown function YJL109C YJL109C 1.6 11 5.3 0.7596 0.586319502 iYJL109C 0.697114191 0.834526454 0.858755686 YJL109C -- unknown -- weak similarity to Drs2p YBL024W NCL1 1.5 10 5.3 0.7596 0.840248285 iYBL025W 0.166133454 0.942294694 0.379347958 "NCL1 -- unknown -- Methyltransferase that methylates cytidine to 5-methyl-cytidine (m5C) at several positions in different tRNAs, has similarity to human proliferating cell nucleolar antigen (p120), a proliferation antigen of human tumors" YDR083W YDR083W 1.5 10 5.3 0.7596 0.267428376 iYDR082W 0.538510513 0.237596087 0.428698034 YDR083W -- unknown -- cleavage at site A2 in pre-rRNA in the pathway of ribosomal RNA processing YBR247C ENP1 1.3 10 5.3 0.7596 0.289114436 iYBR247C 0.084357729 0.401991614 0.222484277 ENP1 -- protein glycosylation -- Essential nuclear effects on N-glycosylation of proteins in the secretory pathway YAR002W NUP60 1.2 9 5.3 0.7596 0.338644744 iYAL001C CEN1 0.283867159 0.793589121 0.386400258 0.552472372 0.597331661 NUP60 -- unknown -- Nuclear pore protein (nucleoporin) YBL022C PIM1 2.4 17 5.2 0.7558 1 0.933206917 iYBL022C 0.99363863 0.681598453 0.663568773 "PIM1 -- respiration -- Serine protease required for intramitochondrial proteolysis and maintenance of respiratory function, related to E. coli ATP-dependent protease La, member of AAA+ family of putative ATPases" YPL262W FUM1 3.1 22 5.2 0.7558 0.147105012 iYPL263C 0.293100117 0.415006988 0.283858998 "FUM1 -- TCA cycle -- Fumarate hydratasemitochondrial and cytoplasmic fumarase, converts L-malate to fumarate as part of TCA cycle" YBR151W APD1 2.6 18 5.2 0.7558 0.293613198 iYBR150C 0.594337097 0.303443795 0.574282952 "APD1 -- cytoskeleton (putative) -- normal cellular structure, localization of actin patches, and resistance to copper" YBR164C ARL1 2.5 18 5.2 0.7558 0.232806368 iYBR164C 0.314041092 0.720435348 0.435949082 "ARL1 -- secretion -- GTP-binding arf-sar family in the ras superfamily, possibly involved in signal transduction" YDL143W CCT4 2.4 17 5.2 0.7558 0.423363822 iYDL144C 0.262360483 0.488028731 0.503898635 "CCT4 -- protein folding -- Component of Chaperonin-containing T-complex(TCP ring complex, TRiC), homologous to mouse CCT4" YOR039W CKB2 2.4 17 5.2 0.7558 0.397781172 iYOR038C 0.07715158 0.736495643 0.275331936 "CKB2 -- salt tolerance -- Casein kinase II Protein kinase CK2, regulatory (beta-prime) subunit" YFR006W YFR006W 2.2 16 5.2 0.7558 0.594417943 iYFR005C 0.053423992 0.936593619 0.093729695 YFR006W -- unknown -- weak similarity to human X-pro dipeptidase YDR115W YDR115W 2.1 15 5.2 0.7558 0.583193355 0.745327103 YDR115W -- unknown -- similarity to prokaryotic L34 ribosomal protein YLR291C GCD7 2.1 15 5.2 0.7558 0.708900236 iYLR291C 0.500176857 0.854817918 0.492040286 "GCD7 -- protein synthesis -- Translation initiation factor eIF2B (guanine nucleotide exchange factor), 43 kDa (beta) subunit" YHR063C YHR063C 1.9 14 5.2 0.7558 0.587947323 iYHR063C 0.369029912 0.774300234 0.355387071 "YHR063C -- unknown -- Putative ketopantoate reductase (2-dehydropantoate 2-reductase) involved in coenzyme A synthesis, has similarity to Cbs2p" YIR035C YIR035C 1.9 14 5.2 0.7558 0.371641866 iYIR035C 0.520952216 0.84509178 0.407186594 YIR035C -- unknown -- similarity to proteins of human corticosteroid 11-beta-dehydrogenase and short-chain alcohol dehydrogenase family YDR127W ARO1 1.8 13 5.2 0.7558 0.412499221 iYDR126W 0.129521591 0.504799548 0.339664804 ARO1 -- aromatic amino acid biosynthesis -- Arom pentafunctional enzyme YJR069C HAM1 1.8 13 5.2 0.7558 0.308406166 iYJR069C 0.491027646 0.592505241 0.095587642 HAM1 -- 6-N-hydroxylaminopurine resistance -- controlling 6-N-hydroxylaminopurine sensitivity and mutagenesis YML053C YML053C 1.8 13 5.2 0.7558 0.535291187 iYML053C 0.505701537 0.289832285 0.506900769 YML053C -- unknown -- unknown function YOR159C SME1 1.8 13 5.2 0.7558 0.044750539 iYOR159C 0.283022579 0.070869912 0.165108629 "SME1 -- mRNA splicing -- Spliceosomal snRNA-associated Sm core mRNA splicing, also likely associated with telomerase TLC1 RNA" YFL002C SPB4 1.7 12 5.2 0.7558 0.469092347 iYFL002C 0.488667638 0.867608837 0.292292849 "SPB4 -- rRNA processing, 25S -- ATP-dependent RNA helicase of DEAH box familyrequired for processing of of 25S ribosomal RNA precursor" YIL039W YIL039W 1.7 12 5.2 0.7558 0.701007847 iYIL040W 0.303916708 0.869060098 0.32781345 YIL039W -- unknown -- unknown function YDL048C STP4 1.2 9 5.2 0.7558 0.253149722 iYDL048C-0 iYDL048C-1 0.424348861 0.342138379 0.205849178 0.354509178 0.255474624 "STP4 -- tRNA splicing -- strong similarity to Stp1p, which is involved in tRNA splicing and branched-chain amino acid uptake" YGR145W YGR145W 1.1 8 5.2 0.7558 0.537663799 iYGR144W 0.365284782 0.441141974 0.192522711 YGR145W -- unknown -- similarity to MESA gene of Plasmodium falciparum YDL031W DBP10 1.8 13 5.1 0.7515 1 0.495007989 iYDL032W 0.782064598 0.43973574 0.562071469 "DBP10 -- unknown -- Putative RNA helicase involved in ribosome biogenesis, has similarity to RNA helicases of DEAD/DEAH box family" YCR009C RVS161 3.5 26 5.1 0.7515 0.684852985 iYCR009C 0.301099931 0.622426177 0.123602376 "RVS161 -- cytoskeleton -- viability after N, C, or S starvation, for internalization step of endocytosis, and for cell fusion during matingroles in endocytosis and in cell fusion are independent of one another" YDL097C RPN6 2.8 20 5.1 0.7515 0.593272402 iYDL097C 0.462565766 0.664717349 0.680078993 RPN6 -- protein degradation -- Non-ATPase subunit of 26S proteasome complex YHR132C ECM14 2.8 21 5.1 0.7515 0.18198626 iYHR132C 0.153098185 0.510392024 0.228012769 ECM14 -- cell wall biogenesis -- Protein possibly involved in cell wall structure or biosynthesis YGR024C YGR024C 2.7 20 5.1 0.7515 0.767666211 0.825937749 YGR024C -- unknown -- unknown function YMR074C YMR074C 2.7 19 5.1 0.7515 0.443379875 iYMR074C 0.238841436 0.896914142 0.395061728 YMR074C -- unknown -- unknown function YHR152W SPO12 2.4 17 5.1 0.7515 0.222500746 iYHR151C 0.35514504 0.351364522 0.066926576 SPO12 -- meiosis; mitotic cell cycle -- Sporulation chromosome division in meiosis I YOR089C VPS21 2.4 17 5.1 0.7515 0.140569503 iYOR089C 0.442615429 0.430719838 0.340409775 "VPS21 -- endocytosis -- GTP-binding sorting of vacuolar proteins and involved in late stage of endocytosis, member of rab family in the ras superfamily" YLL025W YLL025W 2.1 16 5.1 0.7515 0.726369903 iYLL026W iYLLCdelta1 0.413516374 0.635267279 0.476364522 0.869273743 0.654349561 YLL025W -- unknown -- Member of seripauperin (PAU) family YGR083C GCD2 2 14 5.1 0.7515 0.285436627 iYGR083C 0.640582732 0.333709768 0.540686432 "GCD2 -- protein synthesis -- Translation initiation factor eIF2B (guanine nucleotide exchange factor), 71 kDa (delta) subunit" YHR181W YHR181W 2 14 5.1 0.7515 0.528007123 iYHR180W itT(UGU)H 0.075674339 0.794472192 0.872386273 0.284503843 0.57497863 "YHR181W -- unknown -- unknown function, has 4 potential transmembrane domains" YML010W-A 2 14 5.1 0.7515 YDL226C GCS1 1.9 14 5.1 0.7515 0.347376914 iYDL226C 0.622969964 0.736111111 0.633259278 "GCS1 -- secretion -- GTPase-activating protein (GAP) for ADP-ribosylation factors Arf1p and Arf2p, member of Gcs1p/Glo3p/Sps18p family" YPR023C YPR023C 1.9 14 5.1 0.7515 0.045015655 iYPR023C 0.216326888 0.118415746 0.331531822 YPR023C -- unknown -- unknown function YCR016W YCR016W 1.7 12 5.1 0.7515 0.196734306 iYCR015C SNR33 0.71492119 0.332006864 0.213842059 0.505708919 0.154269753 YCR016W -- unknown -- unknown function YDR232W HEM1 1.7 12 5.1 0.7515 0.35118214 iYDR231C 0.558968779 0.710037175 0.814284539 "HEM1 -- heme biosynthesis -- 5-Aminolevulinate synthase, first step in heme biosynthesis pathway" YJR068W RFC2 1.6 11 5.1 0.7515 0.684335185 iYJR067C 0.315289932 0.94371345 0.175759072 "RFC2 -- DNA replication -- Replication factor C, second subunit, homologous to human 37 kDa subunit" YML055W SPC2 1.6 11 5.1 0.7515 0.762230574 0.829452161 SPC2 -- secretion -- Component of signal peptidase complex YNL087W YNL087W 1.6 11 5.1 0.7515 0.173887568 iYNL088W 0.347207396 0.392817239 0.469161957 YNL087W -- unknown -- unknown function YAR008W SEN34 1.5 10 5.1 0.7515 0.635349529 iYAR007C 0.087857507 0.680389945 0.155360168 "SEN34 -- tRNA splicing -- tRNA splicing endonuclease, gamma subunit, has active site for 3' splice site cleavage" YJL134W LCB3 1.5 11 5.1 0.7515 0.951768031 0.291796202 "LCB3 -- sphingolipid metabolism -- Sphingoid base-phosphate phosphatase, putative regulator of sphingolipid metabolism and stress response" YJR001W YJR001W 1.5 11 5.1 0.7515 0.679614229 iYJL001W CEN10 0.395354471 0.641552326 0.961176088 0.356025539 0.420140378 YJR001W -- unknown -- Putative membrane transporter of amino acid/auxin permease (AAAP) family YLR003C YLR003C 1.3 10 5 0.7485 1 0.963725004 iYLR003C 0.756237791 0.714769702 0.166290682 YLR003C -- unknown -- unknown function YKR048C NAP1 3.6 27 5 0.7485 0.242930537 iYKR048C 0.157636204 0.505310793 0.178994918 "NAP1 -- chromatin structure -- Nucleosome assembly plays a role in assembly of histones into octamer, required for full expression of Clb2p functions" YLR304C ACO1 3.1 23 5 0.7485 0.634928683 iYLR304C 0.741757524 0.645171588 0.377394954 "ACO1 -- TCA cycle -- Aconitate hydratase (aconitase), converts citrate to cis-aconitate" YBL007C SLA1 2.9 22 5 0.7485 0.477502011 iYBL007C 0.097212213 0.775026216 0.086352753 "SLA1 -- cytoskeleton -- assembly of cortical actin cytoskeleton, has three SH3 domains" YGL137W SEC27 2.6 19 5 0.7485 0.756313399 iYGL138C 0.581727278 0.487629689 0.703990423 "SEC27 -- secretion -- Coatomer (COPI) complex beta' chain (beta'-COP) of secretory pathway vesiclesrequired for retrograde transport from Golgi to endoplasmic reticulum, member of WD (WD-40) repeat family" YDL092W SRP14 2.4 18 5 0.7485 0.504313264 iYDL093W 0.602453691 0.411139726 0.872630475 "SRP14 -- secretion -- Signal recognition particle subunit, has strong similarity to mammalian SRP14 subunit" YDR167W TAF25 1.9 14 5 0.7485 0.166094978 iYDR166C 0.831309697 0.823830409 0.808874913 "TAF25 -- transcription -- Component of TAF(II) complex (TBP-associated protein complex) and SAGA complex (Spt-Ada-Gcn5-acetyltransferase), required for activated transcription by RNA polymerase II" YER095W RAD51 1.8 13 5 0.7485 0.374008672 iYER094C 0.160363637 0.183370931 0.274699428 "RAD51 -- DNA repair and recombination -- stimulates pairing and strand-exchange between homologous single-stranded and double-stranded DNA, functionally similar to E. coli RecA protein" YIL177C YIL177C 1.8 12.5 5 0.7485 0.963573995 iYHR219W iYIL177C-0 0.977859297 0.994824164 0.571134699 0.022216737 0.080538085 "YIL177C -- unknown -- similarity to subtelomerically-encoded proteins including Yjl225p, Yfl068p, and Yhl093p" YJL124C LSM1 1.8 14 5 0.7485 0.67698368 iYJL124C 0.035890058 0.723142214 0.095435348 "LSM1 -- mRNA splicing (putative) -- Sm class of RNA-binding proteins, involved in control of mRNA decay" YLR172C DPH5 1.8 14 5 0.7485 0.524283805 iYLR172C 0.709008188 0.812777285 0.656743815 "DPH5 -- diphthamide biosynthesis -- Diphthamide methyltransferase, required for diphthamide biosynthesis" YML018C YML018C 1.7 12 5 0.7485 0.686567341 iYML018C 0.304058164 0.906300354 0.693820456 YML018C -- unknown -- unknown function YOL020W SCM2 1.7 13 5 0.7485 0.473832302 iYOL021C 0.327677194 0.616609837 0.528598603 "SCM2 -- transport -- Tryptophan permease, high affinity" YOR320C YOR320C 1.7 12 5 0.7485 0.647163018 iYOR320C 0.453284537 0.417756932 0.372903564 YOR320C -- unknown -- similarity to K. lactis N-acetylglucosaminyltransferase YML019W OST6 1.3 10 5 0.7485 0.666229114 iYML020W 0.373773207 0.930474334 0.552513966 OST6 -- protein glycosylation -- Oligosaccharyltransferase subunit of 37 kDa YFL014W HSP12 3.4 25 4.9 0.7452 1 0.944622299 iYFL015C 0.962757269 0.279082678 0.294028273 "HSP12 -- glucose and lipid utilization -- Heat shock 12 kDa, induced by heat, osmotic stress, oxidative stress and in stationary phase" YPL226W NEW1 2.5 18 4.9 0.7452 1 0.742587391 iYPL227C 0.955560952 0.31141261 0.323463687 NEW1 -- unknown -- Member of non-transporter group of ATP-binding cassette (ABC) superfamily YDR408C ADE8 2.2 17 4.9 0.7452 1 0.840769125 iYDR408C 0.9351431 0.791991553 0.625312576 "ADE8 -- purine biosynthesis -- Phosphoribosylglycinamide formyltransferase (GART), third step in de novo purine biosynthesis pathway" YNL154C YCK2 2.1 16 4.9 0.7452 1 0.85790571 iYNL154C 0.971615723 0.641420591 0.261208577 YCK2 -- unknown -- Casein kinase I isoform YOR302W YOR302W 2.7 20 4.9 0.7452 0.2709098 iYOR301W 0.935960453 0.056035547 0.326619401 "YOR302W -- unknown -- Arginine attenuator peptide, mediates translational regulation of a downstream geneencoded by the 5'-leader of carbamyl-phosphate synthetase small subunit (CPA1) mRNA" YOR207C RET1 2.4 18 4.9 0.7452 0.398711521 iYOR207C 0.017275553 0.677811795 0.010220126 "RET1 -- transcription -- RNA polymerase III, second-largest subunit (C128)" YKR018C YKR018C 2.2 17 4.9 0.7452 0.274984343 iYKR018C 0.149900816 0.848269743 0.193899966 YKR018C -- unknown -- unknown function YPR181C SEC23 2.2 17 4.9 0.7452 0.081774465 iYPR181C 0.595905382 0.132066277 0.198261858 "SEC23 -- secretion -- Component of COPII coat of vesicles involved in endoplasmic reticulum to Golgi transport, has GTPase-activation (GAP) activity for Sar1p" YDL135C RDI1 2.1 16 4.9 0.7452 0.89434988 iYDL135C 0.718356743 0.821787709 0.692657622 RDI1 -- signaling -- Rho GDP dissociation inhibitor (rho GDI) with activity towards Rho1p YMR203W TOM40 2.1 17 4.9 0.7452 0.434239776 iYMR202W 0.433954984 0.843591191 0.233187135 TOM40 -- mitochondrial protein targeting -- Forms mitochondrial outer membrane import channelintegral outer membrane protein import YBL026W LSM2 2 15.5 4.9 0.7452 0.914488729 iYBL027W 0.728384719 0.908746811 0.779068043 LSM2 -- mRNA splicing -- U6 snRNA-associated Sm-like group YCR090C YCR090C 2 16 4.9 0.7452 0.761597517 iYCR090C-0 iYCR090C-1 0.599159867 0.081383281 0.825733161 0.77014295 0.091335473 YCR090C -- unknown -- unknown function YIR006C PAN1 1.8 14 4.9 0.7452 0.408956597 iYIR006C itE(UUC)I 0.506956588 0.792105475 0.181165204 0.493458405 0.426232206 PAN1 -- cytoskeleton and endocytosis -- organization of actin cytoskeleton and in endocytosis YKL127W PGM1 1.8 13 4.9 0.7452 0.638241613 iYKL128C itK(CUU)K 0.853569694 0.68225225 0.845724907 0.932748899 0.803721174 "PGM1 -- glycolysis -- Phosphoglucomutase, minor isoform, interconverts Glc-1-P and Glc-6-P" YDL148C YDL148C 1.7 12 4.9 0.7452 0.329744082 iYDL148C 0.34709714 0.245411014 0.437928531 YDL148C -- unknown -- Nuclear unknown function YNL124W YNL124W 1.7 13 4.9 0.7452 0.062128849 iYNL125C 0.062573782 0.089993502 0.131901588 YNL124W -- unknown -- unknown function YEL042W GDA1 1.3 10 4.9 0.7452 0.550652785 iYEL043W 0.47783768 0.545038098 0.503786658 GDA1 -- Golgi organization -- Guanosine diphosphatase of Golgi membrane YBL081W YBL081W 1.3 10 4.8 0.7418 1 0.610097275 iYBL082C 0.939385673 0.228948288 0.454851983 YBL081W -- unknown -- 37% identity to Drosophila l (2)not protein YNL156C YNL156C 3.3 25 4.8 0.7418 0.284490379 iYNL156C 0.493966305 0.634708347 0.59587496 YNL156C -- unknown -- unknown function YDL111C RRP42 2.6 19 4.8 0.7418 0.457234015 iYDL111C 0.437398756 0.844962491 0.456871345 "RRP42 -- rRNA processing -- Component of exosome 3'-5' exoribonuclease complex that is required for 3' processing of ribosomal 5.8S rRNA, of snoRNAS, and of U4 snRNA" YGR007W MUQ1 2.2 17 4.8 0.7418 0.584907719 iYGR006W 0.19589851 0.723654528 0.269097362 MUQ1 -- phospholipid metabolism -- Ethanolaminephosphate cytidylyltransferase YOR009W YOR009W 2.2 18 4.8 0.7418 0.176621915 iYOR008C-A 0.495709892 0.223322518 0.293631939 YOR009W -- unknown -- Member of seripauperin (PAU) family of possible cell wall mannoproteins YPL098C YPL098C 2.2 18 4.8 0.7418 0.033196163 iYPL098C 0.208660408 0.080363382 0.03879971 YPL098C -- unknown -- unknown function YBR042C YBR042C 2 15 4.8 0.7418 0.617012417 iYBR042C 0.263639439 0.75974863 0.127154444 YBR042C -- unknown -- Putative acyltransferase with similarity to Ydr018p YKL170W MRPL38 1.7 13 4.8 0.7418 0.476641506 iYKL171W 0.579062949 0.665442937 0.480870021 MRPL38 -- protein synthesis -- Mitochondrial ribosomal large subunit (YmL38) YLL031C GPI13 1.6 12 4.8 0.7418 0.256446332 iYLL031C 0.799336247 0.580601555 0.422868623 "GPI13 -- unknown -- glycosylphosphatidylinositol biosynthesis, probably responsible for adding phosphoethanolamine to the third mannose" YOL012C HTA3 1.6 12 4.8 0.7418 0.703336852 iYOL012C 0.360315012 0.594341079 0.498227558 HTA3 -- chromatin structure -- Histone-related can suppress histone H4 point mutation YER118C SHO1 1.5 11 4.8 0.7418 0.749433455 iYER118C 0.353098698 0.873024741 0.44420078 "SHO1 -- signaling, high osmolarity pathway -- Osmosensor in the HOG1 MAP kinase, high-osmolarity signal transduction pathway, has an SH3 domain" YML035C AMD1 1.5 12 4.8 0.7418 0.190221791 iYML035C 0.183217008 0.564290706 0.443632229 "AMD1 -- protein glycosylation -- AMP deaminase, converts AMP to IMP and ammonia" YNR009W YNR009W 1.3 10 4.8 0.7418 0.054333443 iYNR008W 0.310214696 0.17387631 0.121722997 YNR009W -- unknown -- unknown function YMR310C YMR310C 1.2 10 4.8 0.7418 0.198466673 iYMR310C 0.040489392 0.451083159 0.036305594 YMR310C -- unknown -- unknown function YNL217W YNL217W 1.2 10 4.8 0.7418 0.875567291 iYNL218W 0.882629108 0.639552437 0.913168396 YNL217W -- unknown -- Protein possibly involved in cytoplasmic ribosome function YPL063W YPL063W 1.2 9 4.8 0.7418 0.38255344 iYPL064C 0.547384783 0.596967279 0.61797209 YPL063W -- unknown -- unknown function YPL256C CLN2 1.2 10 4.8 0.7418 0.213166042 iYPL256C 0.130227367 0.153007773 0.154776598 "CLN2 -- cell cycle -- G1/S-specific cyclin, interacts with Cdc28p protein kinase to control events at START" YAL033W POP5 1.2 10 4.7 0.7377 1 0.956388282 iYAL034C 0.992893737 0.754834032 0.673907677 "POP5 -- tRNA processing -- Subunit of both RNase P and RNase MRP, which are involved in tRNA processing and 5.8S rRNA processing, respectively" YLR350W YLR350W 2.7 22 4.7 0.7377 0.24357529 iYLR349W 0.29789869 0.550133097 0.242023848 YLR350W -- unknown -- unknown function YMR315W YMR315W 2.7 21 4.7 0.7377 0.429700433 iYMR314W 0.394387265 0.811231067 0.56372865 YMR315W -- unknown -- unknown function YKR066C CCP1 2.6 20 4.7 0.7377 0.121399085 iYKR066C 0.559358887 0.564083821 0.923557969 "CCP1 -- oxidative stress response -- Cytochrome-c peroxidase, involved in destruction of toxic radicals in the cell" YML069W POB3 2.5 19 4.7 0.7377 0.250326691 iYML070W 0.160527409 0.563491931 0.136645963 POB3 -- DNA replication (putative) -- binds to DNA polymerase I YGL019W CKB1 1.9 15 4.7 0.7377 0.166698102 iYGL020C 0.087253562 0.410202655 0.089424951 "CKB1 -- salt tolerance -- Casein kinase II (Protein kinase CK2), regulatory (beta) subunit" YML077W BET5 1.8 14 4.7 0.7377 0.586670878 iYML078W 0.641363661 0.625812216 0.828731045 BET5 -- secretion (putative) -- TRAPP (Transport Protein Particle) complex involved in vesicular transport from endoplasmic reticulum to the Golgi YPR053C 1.7 13 4.7 0.7377 0.435506064 0.701884308 YBR248C HIS7 1.6 12 4.7 0.7377 0.357697912 iYBR248C 0.266923508 0.418151642 HIS7 -- histidine biosynthesis -- Glutamine amidotransferase YKR070W YKR070W 1.6 12 4.7 0.7377 0.524854991 iYKR069W 0.35353137 0.929174789 0.494232476 YKR070W -- unknown -- unknown function YLR130C ZRT2 1.6 12 4.7 0.7377 0.412824924 iYLR130C 0.667643791 0.62157492 0.613734783 "ZRT2 -- transport -- Low-affinity zinc transport protein, member of ZIP family of metal ion transporters" YLR407W YLR407W 1.6 13 4.7 0.7377 0.94418157 iYLR406C 0.996825698 0.911625549 0.935035914 YLR407W -- unknown -- unknown function YOR115C TRS33 1.6 12 4.7 0.7377 0.101887999 iYOR115C 0.628254724 0.501933613 0.592917479 TRS33 -- secretion (putative) -- TRAPP (Transport Protein Particle) complex involved in protein transport from endoplasmic reticulum to Golgi YDR367W 1.5 12 4.7 0.7377 0.753928738 0.977813248 YIR029W DAL2 1.5 12 4.7 0.7377 0.145822869 iYIR028W 0.482215549 0.249563242 0.62555457 "DAL2 -- allantoin utilization -- Allantoicase, carries out the second step in the degradation of allantoinallows purines to be used as nitrogen sources" YML075C HMG1 1.5 12 4.7 0.7377 0.568527382 iYML075C 0.671408256 0.507089913 0.927853152 "HMG1 -- sterol metabolism -- 3-Hydroxy-3-methylglutaryl-coenzyme A reductase 1, rate limiting enzyme for sterol biosynthesis, converts HMG-CoA to mevalonate" YDL003W MCD1 1.3 10 4.7 0.7377 0.285508921 iYDL004W 0.523116416 0.404286175 0.410273741 "MCD1 -- mitosis, sister chromatid cohesion -- Cohesin, mitotic chromatid cohesion" YKL113C RAD27 1.3 10 4.7 0.7377 0.329446148 iYKL113C 0.095336791 0.503625524 0.335594573 RAD27 -- DNA repair -- Single-stranded DNA endonuclease and 5'-3' exonuclease that functions in the MSH2-MLH1-PMS1-dependent mismatch repair system YPR005C HAL1 1.3 11 4.7 0.7377 0.147581381 iYPR005C 0.101927475 0.167103424 0.111102159 HAL1 -- salt tolerance -- ion homeostasis YHL013C YHL013C 1.2 10 4.7 0.7377 0.48747142 iYHL013C 0.294803303 0.94035147 0.02997076 YHL013C -- unknown -- unknown function YLR068W YLR068W 1.2 9 4.7 0.7377 0.090876088 iYLR067C 0.333615938 0.111722572 0.066507205 YLR068W -- unknown -- unknown function YJR058C APS2 1.8 14 4.6 0.7319 1 0.968200095 iYJR058C 0.983866033 0.704191033 0.144737925 "APS2 -- secretion -- Clathrin-associated protein (AP) complex, small subunit" YGR283C YGR283C 1.5 12 4.6 0.7319 1 0.959815268 iYGR283C 0.949954929 0.721879371 0.484324237 YGR283C -- unknown -- unknown function YGL037C PNC1 6.5 52 4.6 0.7319 0.831270347 iYGL037C 0.344123974 0.806341719 0.095929769 PNC1 -- unknown -- Pyrazinamidase and nicotinamidase YPL048W CAM1 3.1 26 4.6 0.7319 0.36912767 iYPL049C 0.31983238 0.663293014 0.296552292 CAM1 -- protein synthesis -- Translation elongation factor EF-1gamma YER021W RPN3 3 25 4.6 0.7319 0.689051149 iYER020W 0.311382399 0.966403481 0.227071066 RPN3 -- protein degradation -- Non-ATPase component of 26S proteasome complex YKL157W APE2 3 24 4.6 0.7319 0.926375929 iYKL158W 0.326085637 0.82485637 0.298217311 "APE2 -- protein degradation -- Aminopeptidase II (yscII), plays a nutritional role in releasing leucine from peptides externally cleaved at leucine" YBL058W SHP1 2.8 23 4.6 0.7319 0.653313928 iYBL059W 0.87733522 0.919632881 0.886671987 SHP1 -- glucose repression -- Potential regulatory subunit for Glc7p YOR117W RPT5 2.8 23 4.6 0.7319 0.50336428 iYOR116C 0.34392447 0.848034438 0.437751995 "RPT5 -- protein degradation -- ATPase component of 26S proteasome complex, member of AAA family of ATPases" YBR035C PDX3 2.7 21 4.6 0.7319 0.56192191 iYBR035C iTLC1 0.305555225 0.645261686 0.893955276 0.200197482 0.440793093 PDX3 -- sterol uptake (putative) -- Pyridoxine (pyridoxamine) phosphate oxidase[P (N/M)P oxidase] YER141W COX15 2.7 21 4.6 0.7319 0.427782739 iYER140W 0.421126666 0.763051885 0.425022183 COX15 -- respiration -- cytochrome oxidase assembly YCR035C RRP43 2.5 20 4.6 0.7319 0.398642185 iYCR035C 0.292014083 0.654488604 0.319606888 "RRP43 -- rRNA processing -- Component of exosome 3'-5' exoribonuclease complex that is required for 3' processing of ribosomal 5.8S rRNA, of snoRNAs, and of U4 snRNA" YDL066W IDP1 2.5 20 4.6 0.7319 0.536853413 iYDL067C 0.331189849 0.633368861 0.31007097 "IDP1 -- TCA cycle -- Isocitrate dehydrogenase (NADP+), mitochondrial" YDL195W SEC31 2.5 20 4.6 0.7319 0.216003052 iYDL196W 0.362274069 0.361827264 0.484649123 "SEC31 -- secretion -- Component (p150) of COPII coat of secretory pathway vesicles involved in endoplasmic reticulum to Golgi transportassociated with Sec13p, member of WD (WD-40) repeat family" YKL028W TFA1 2.5 20 4.6 0.7319 0.310259302 iYKL029C 0.865540771 0.648124501 0.405267358 "TFA1 -- transcription -- RNA polymerase II transcription initiation factor TFIIE (factor a), 66 kDa subunit" YFR051C RET2 2.4 19 4.6 0.7319 0.270584201 iYFR051C 0.164495071 0.529824265 0.337984996 RET2 -- secretion -- Coatomer (COPI) complex delta chain (delta-COP) of secretory pathway vesiclesrequired for retrograde Golgi to endoplasmic reticulum transport YNL263C YIF1 2.4 19 4.6 0.7319 0.221970751 iYNL263C 0.16353584 0.745451592 0.669052909 YIF1 -- unknown -- Essential unknown functionhas similarity to NADH dehydrogenases YMR236W TAF17 2.2 18 4.6 0.7319 0.371087239 iYMR235C 0.34936877 0.70525127 0.215778011 TAF17 -- transcription -- Component of TAF(II) complex (TBP-associated protein complex) and the SAGA HAT complex YDR468C TLG1 2 17 4.6 0.7319 0.2730123 iYDR468C 0.508739339 0.389698017 0.345922677 "TLG1 -- endocytosis -- Syntaxin homolog (t-SNARE), involved in efficient endocytosis and in maintenance of resident proteins in the trans-Golgi network" YEL002C WBP1 1.9 15 4.6 0.7319 0.726264169 iYEL002C 0.753195595 0.861760884 0.897685029 "WBP1 -- protein glycosylation -- Oligosaccharyltransferase beta subunit, member of a complex of 8 ER proteins that transfers core oligosaccharide from dolichol carrier to Asn-X-Ser/Thr motif" YHR188C YHR188C 1.9 15 4.6 0.7319 0.543808019 iYHR188C 0.5206696 0.93282976 0.677408959 YHR188C -- unknown -- Protein possibly involved in the TCA cycle YOR306C YOR306C 1.9 15 4.6 0.7319 0.38337698 iYOR306C 0.535649465 0.202912861 0.333870448 "YOR306C -- unknown -- similarity to human X-linked PEST-containing transporter, member of monocarboxylate porter (MCP) family of major facilitator superfamily (MFS)" YDR063W YDR063W 1.8 15 4.6 0.7319 0.976644066 iYDR062W 0.935224425 0.782527881 0.497408047 YDR063W -- unknown -- unknown function YDR395W SXM1 1.6 13 4.6 0.7319 0.649595832 iYDR394W 0.394362575 0.950617284 0.331546459 SXM1 -- mRNA export; nuclear protein targeting -- Beta-karyopherin involved in nuclear protein import of mRNA-binding proteins YER156C YER156C 1.6 12 4.6 0.7319 0.876311761 iYER156C 0.238641273 0.975104737 0.390106349 YER156C -- unknown -- unknown function YHR072W ERG7 1.6 12 4.6 0.7319 0.563692458 iYHR071W itF(GAA)H1 0.792455885 0.81198682 0.829369513 0.446766922 0.236760884 ERG7 -- sterol metabolism -- Lanosterol synthasecarries out complex cyclization step of squalene to lanosterol in ergosterol biosynthesis pathway YBR242W YBR242W 1.5 12 4.6 0.7319 0.278716152 iYBR241C 0.64440667 0.49431449 0.666290232 YBR242W -- unknown -- normal growth rate on glucose and for normal copper sensitivity YKL144C RPC25 1.5 12 4.6 0.7319 0.580730458 iYKL144C 0.403711658 0.735177866 0.414498141 "RPC25 -- transcription -- RNA polymerase III, subunit C25" YGL099W YGL099W 1.3 11 4.6 0.7319 0.540848674 iYGL100W 0.460021454 0.725633528 0.68216728 "YGL099W -- unknown -- normal growth, morphology, mating, and sporulationhas similarity to human possible GTP-binding protein HSR1" YPL049C DIG1 1.2 10 4.6 0.7319 0.062634275 iYPL049C 0.31983238 0.1685884 0.296552292 DIG1 -- invasive growth -- MAP kinase-associated negative regulation of invasive growth YOR344C TYE7 1.9 16 4.5 0.7268 1 0.574329487 iYOR344C-0 iYOR344C-1 0.973512779 0.905107682 0.202480783 0.527881041 0.709273521 TYE7 -- glycolysis -- Basic helix-loop-helix transcription factor that can suppress the Gcr1p requirement for glycolytic gene expression YOL136C PFK27 1.7 14 4.5 0.7268 1 0.848372013 iYOL136C 0.944342485 0.901118099 0.295555376 "PFK27 -- fructose metabolism -- 6-Phosphofructose-2-kinase, isozyme 2" YHR049W YHR049W 4.7 39 4.5 0.7268 0.592088746 iYHR048W 0.706249955 0.797695778 0.736240241 YHR049W -- unknown -- unknown function YAL016W TPD3 3.3 27 4.5 0.7268 0.591458123 iYAL017W 0.100259572 0.846293096 0.206943336 "TPD3 -- tRNA biosynthesis, cytokinesis, ceramide-mediated signaling -- Protein serine/threonine phosphatase 2A (PP2A) regulatory subunit A, ceramide-activated protein phosphatase A subunit" YDL140C RPO21 2.9 24 4.5 0.7268 0.147426829 iYDL140C 0.721555102 0.201083159 0.646471157 "RPO21 -- transcription -- RNA polymerase II, largest subunit" YDL171C GLT1 2.9 24 4.5 0.7268 0.261351768 iYDL171C 0.595067293 0.33580705 0.666419814 "GLT1 -- glutamate biosynthesis -- Glutamate synthase (NADPH, GOGAT)involved with glutamine synthetase (Gln1p) in glutamate biosynthesis" YJL121C RPE1 2.6 21 4.5 0.7268 0.332890651 0.639348229 "RPE1 -- pentose phosphate cycle -- Ribulose-5-phosphate 3-epimerase, interconverts ribulose-5-phosphate and xylulose-5-phosphate" YNL056W YNL056W 2.6 21 4.5 0.7268 0.674108955 iYNL057W 0.417728116 0.779455721 0.697368421 YNL056W -- unknown -- similarity to Siw14p and Ynl099cp protein tyrosine phosphatases (PTP's) and which may compete with PTP's for substrates YDR194C MSS116 2.5 20 4.5 0.7268 0.774169474 iYDR194C 0.261595418 0.963658424 0.274807827 "MSS116 -- mRNA splicing, mitochondrial -- Mitochondrial RNA helicase of DEAD box family, required for splicing of group II introns of COX1 and COB" YPR086W SUA7 2.4 20 4.5 0.7268 0.123028169 iYPR085C 0.237089202 0.158805031 0.13471001 "SUA7 -- transcription -- RNA polymerase II transcription initiation factor TFIIB (factor e), functions in selection of site for transcriptional initiation" YKL146W YKL146W 2.2 18 4.5 0.7268 0.311081772 0.2735834 YKL146W -- unknown -- Putative membrane transporter of amino acid/auxin permease (AAAP) family YER088C DOT6 2.1 18 4.5 0.7268 0.221271695 iYER088C 0.460105162 0.140480942 0.234623184 DOT6 -- silencing (telomere) -- telomere silencing YNR052C POP2 2.1 17 4.5 0.7268 0.193413834 iYNR052C IntYNR053C 0.653807069 0.475438163 0.471398646 POP2 -- glucose derepression -- Component of CCR4 complex required for glucose derepression YDR292C SRP101 2 16 4.5 0.7268 0.370707545 iYDR292C 0.261842535 0.216293047 0.4471668 "SRP101 -- secretion -- Signal recognition particle receptor, alpha subunit, interacts with beta subunit, Srp102p" YNL121C TOM70 1.9 16 4.5 0.7268 0.387845399 iYNL121C 0.275689455 0.341631726 0.312980433 "TOM70 -- mitochondrial protein targeting -- Mitochondrial specialized import receptor of outer membrane, has tetratricopeptide (TPR) repeats" YDR261C EXG2 1.7 14 4.5 0.7268 0.711090806 iYDR261C-0 iYDR261C-1 0.399390388 0.488364032 0.824392998 0.510876571 0.466130604 "EXG2 -- cell wall biogenesis -- Exo-beta-1,3-glucanase (beta-1,3-D-glucanglucanohydrolase), minor isoform" YMR270C RRN9 1.6 12 4.5 0.7268 0.246586441 iYMR270C 0.720916247 0.554266436 0.799965059 "RRN9 -- transcription -- Component of Upstream Activation Factor (UAF) complex, involved in activation of RNA polymerase I" YOR001W RRP6 1.5 12 4.5 0.7268 0.426906265 iYOL001W CEN15 0.600271149 0.759368659 0.779551933 0.583086528 0.498225752 "RRP6 -- rRNA processing, 5.8S -- 5.8S ribosomal RNA 3' end processing, involved in degradation of aberrant poly(A)- mRNAs in the nucleus, component of nuclear form of exosome" YPL263C KEL3 1.5 12 4.5 0.7268 0.066989943 iYPL263C 0.293100117 0.093619078 0.283858998 KEL3 -- unknown -- similarity to Kel1p and Kel2p YER029C SMB1 1.3 11 4.5 0.7268 0.700290183 iYER029C 0.486484716 0.53460039 0.033918595 "SMB1 -- mRNA splicing -- Spliceosomal snRNA-associated Sm core protein, also likely associated with telomerase TLC1 RNA" YDL181W INH1 1.2 10 4.5 0.7268 0.394981173 iYDL182W 0.499338952 0.63819633 0.544486569 INH1 -- ATP synthesis -- Inhibitor of mitochondrial ATPase that forms a complex with ATP synthase to inhibit enzyme activity YJL069C YJL069C 1.2 10 4.5 0.7268 0.219509712 iYJL069C 0.507789924 0.380403461 0.672655495 YJL069C -- unknown -- Essential unknown function YJL186W MNN5 1.2 11 4.5 0.7268 0.439757136 iYJL187C 0.299054294 0.706624102 0.365090968 MNN5 -- protein glycosylation -- Mannosyltransferaserequired for forming and extending the mannose branches of outer chain mannans YKL084W YKL084W 1.2 10 4.5 0.7268 0.434898714 iYKL085W 0.205295334 0.61054256 0.103770545 YKL084W -- unknown -- unknown function YNL040W YNL040W 1.2 10 4.5 0.7268 0.570584426 iYNL041C 0.649701422 0.902110688 0.817031905 YNL040W -- unknown -- unknown function YIL064W YIL064W 1 8 4.5 0.7268 0.50906589 iYIL065C 0.494430234 0.91844887 0.710119239 YIL064W -- unknown -- Predicted methyltransferase protein YOR261C RPN8 2.9 24 4.4 0.7224 0.25600686 iYOR261C 0.176334806 0.531501772 0.351133339 RPN8 -- protein degradation -- Non-ATPase subunit of 26S proteasome complex YJR044C YJR044C 2.7 22 4.4 0.7224 0.424434849 iYJR044C 0.654152263 0.472222222 0.396925227 YJR044C -- unknown -- similarity to Drosophila yakuba NADH dehydrogenase chain 5 YER122C GLO3 2.6 22 4.4 0.7224 0.45272145 iYER122C 0.483179877 0.673083171 0.309429701 "GLO3 -- cell proliferation -- GTPase-activating protein (GAP) for ADP-ribosylation factors Arf1p and Arf2p, involved in retrograde transport between Golgi and ER" YKL002W YKL002W 2.5 21 4.4 0.7224 0.439603996 iYKL003C 0.164667547 0.567031905 0.248630358 "YKL002W -- unknown -- unknown function, has similarity to human BC-2 breast adenocarcinoma marker protein" YNR035C ARC35 2.4 20 4.4 0.7224 0.58973076 iYNR035C 0.151599876 0.613886672 0.265630035 "ARC35 -- cytoskeleton -- Component of ARP2/3 actin-organizing complexinvolved in actin assembly and function, and endocytosis" YPR173C VPS4 2.2 19 4.4 0.7224 0.16827371 iYPR173C 0.214402988 0.138978408 0.15027933 "VPS4 -- vacuolar protein targeting -- vacuolar sorting that causes a novel pre-vacuolar organelle to become prominent, member of AAA ATPase family" YBR029C CDS1 2.1 18 4.4 0.7224 0.609312404 iYBR029C 0.483721685 0.643096568 0.466000645 CDS1 -- lipid metabolism -- CDP-diacylglycerol (CDP-DAG) synthasephosphatidate cytidylyltransferase YNL243W SLA2 2 17 4.4 0.7224 0.504436642 iYNL244C 0.352373365 0.347969707 0.205878822 "SLA2 -- cytoskeleton -- Talin-like membrane cytoskeleton assembly, required for cell polarization, also required for the internalization phase of endocytosis" YGL172W NUP49 1.9 16 4.4 0.7224 0.330884622 iYGL173C 0.452494843 0.773445053 0.783415342 "NUP49 -- nuclear protein targeting -- Nuclear pore protein (nucleoporin) of GLFG familyacts in a complex with Nic96p, Nsp1p, and Nup57p" YKL195W YKL195W 1.9 16 4.4 0.7224 0.221263245 iYKL196C 0.301026728 0.407023144 0.475308642 YKL195W -- unknown -- unknown function YNL336W COS1 1.9 19 4.4 0.7224 iYNL337W 0.990761339 0.271588188 COS1 -- unknown -- Member of COS family of subtelomerically-encoded proteins YDR056C YDR056C 1.8 16 4.4 0.7224 0.226083898 iYDR056C 0.733608548 0.270061728 0.853190288 YDR056C -- unknown -- unknown function YEL024W RIP1 1.8 15 4.4 0.7224 0.587663915 iYEL025C 0.596573841 0.571891498 "RIP1 -- respiration -- Ubiquinol cytochrome-c reductase iron-sulfur protein (Rieske iron-sulfur protein), component of ubiquinol cytochrome-c reductase complex" YML094W GIM5 1.8 15 4.4 0.7224 0.459604251 0.67282407 "GIM5 -- protein folding -- Prefoldin subunit 5, component of Gim protein complex that promotes formation of functional alpha-tubulin, gamma-tubulin, and actin" YBL093C ROX3 1.7 14 4.4 0.7224 0.965712974 iYBL093C 0.98206533 0.738317757 0.655546688 ROX3 -- transcription -- Component of RNA polymerase II holoenzyme and mediator subcomplex YBR254C TRS20 1.7 14 4.4 0.7224 0.430505253 iYBR254C 0.481852301 0.600239425 0.141857977 TRS20 -- secretion (putative) -- TRAPP (Transport Protein Particle) complex involved in vesicular transport from endoplasmic reticulum to Golgi YKR060W YKR060W 1.6 13 4.4 0.7224 0.583661644 iYKR059W 0.565111108 0.949269466 0.340557525 YKR060W -- unknown -- unknown function YDR047W HEM12 1.5 12 4.4 0.7224 0.430235798 iYDR046C 0.585744249 0.365572316 0.776104666 "HEM12 -- heme biosynthesis -- Uroporphyrinogen decarboxylase, carries out sequential decarboxylation of 4 acetyl side chains of uroporphyrinogen to yield coproporphyrinogen" YDR312W SSF2 1.5 12 4.4 0.7224 0.45940848 iYDR311W 0.755534219 0.56217079 0.730260177 SSF2 -- signaling (putative) -- potential role in mating YIL090W YIL090W 1.5 12 4.4 0.7224 0.345155943 iYIL091C 0.024172759 0.502450152 0.038015305 YIL090W -- unknown -- unknown function YOR356W YOR356W 1.2 11 4.4 0.7224 0.695430773 iYOR355W 0.326203986 0.469415343 0.22731306 YOR356W -- unknown -- similarity to human electron transfer flavoprotein-ubiquinone oxidoreductase YML014W YML014W 1.1 10 4.4 0.7224 0.165539467 iYML015C 0.403653055 0.409880007 0.159437947 YML014W -- unknown -- similarity to Diptheria toxin resistance protein YGR026W YGR026W 4 35 4.3 0.7169 0.887242998 0.857718337 YGR026W -- unknown -- similarity to NADH-ubiquinone oxidoreductase chain 5 YIL158W YIL158W 2.7 23 4.3 0.7169 0.525282075 iYIL159W 0.306963921 0.738870447 0.157267161 YIL158W -- unknown -- similarity to Ykr100p YGR231C PHB2 2.6 22 4.3 0.7169 0.230049569 iYGR231C 0.393658637 0.71025248 0.522465113 "PHB2 -- aging -- Prohibitin, involved in determination of replicative lifespanmember of prohibitin complex with Phb1p" YDR373W FRQ1 2.2 19 4.3 0.7169 0.77231106 iYDR372C 0.447827723 0.997563353 0.633258137 FRQ1 -- unknown -- similarity to human BDR-1 protein and other calcium binding proteins YKL126W YPK1 2.2 19 4.3 0.7169 0.452548187 iYKL127W 0.695313128 0.663596214 0.820179218 "YPK1 -- unknown -- Serine/threonine protein kinase with similarity to protein kinase C, possibly involved in a sphingolipid-mediated signaling pathway" YOL068C HST1 2.2 20 4.3 0.7169 0.513668707 iYOL068C 0.402857839 0.558874352 0.204207503 "HST1 -- silencing -- similarity to Sir2p, member of SIR2 family" YDR184C ATC1 2.1 19 4.3 0.7169 0.471984599 iYDR184C 0.342072962 0.681611436 0.247998512 ATC1 -- cell polarity -- cation homeostasisinteracts with Bud6p/Aip3p YPR082C DIB1 1.9 16 4.3 0.7169 0.254543359 iYPR082C 0.203729839 0.485499651 0.118959108 "DIB1 -- unknown -- Component of U4/U6.U5 snRNP, also required for mitotic spindle formation or function" YAL060W YAL060W 1.8 16 4.3 0.7169 0.644585142 iYAL061W 0.481221375 0.724569111 0.836515715 "YAL060W -- unknown -- similarity to alcohol/sorbitol dehydrogenase, member of zinc-containing alcohol dehydrogenase family" YHR069C RRP4 1.8 16 4.3 0.7169 0.268120243 iYHR069C 0.80025672 0.656883298 0.198376532 "RRP4 -- rRNA processing -- 3'-5' exoribonuclease required for 3' processing of ribosomal 5.8S rRNA, component of both the nucleolar and cytoplasmic forms of 3'-5' exosome complex" YHR163W SOL3 1.8 15 4.3 0.7169 0.174041363 iYHR162W 0.784363075 0.484450532 0.775765978 "SOL3 -- tRNA splicing, putative -- Possible 6-phosphogluconolactonase, involved indirectly in tRNA synthesis and function" YLR170C APS1 1.8 15 4.3 0.7169 0.336828892 0.478564963 "APS1 -- secretion -- Clathrin-associated protein (AP) complex, small subunit" YCR072C YCR072C 1.6 14 4.3 0.7169 0.431854784 iYCR072C 0.713484977 0.617877714 0.477212229 "YCR072C -- unknown -- unknown function, member of WD (WD-40) repeat family" YDR170C SEC7 1.6 14 4.3 0.7169 0.39545815 iYDR170C itQ(UUG)D3 0.339530656 0.770678914 0.354694607 0.567925615 0.441397112 SEC7 -- secretion -- Component of non-clathrin vesicle coat required for protein trafficking within the Golgi YGR036C CWH8 1.6 13 4.3 0.7169 0.603147648 iYGR036C 0.369456632 0.741147052 0.438352827 CWH8 -- cell wall biogenesis -- generation of mannolayer of cell wall YKL082C YKL082C 1.6 13 4.3 0.7169 0.506127071 iYKL082C 0.866197137 0.014502095 0.189747387 YKL082C -- unknown -- unknown function YLR050C YLR050C 1.6 14 4.3 0.7169 0.181586038 iYLR050C 0.194408514 0.392603932 0.260802469 YLR050C -- unknown -- similarity to C-terminal region of human MAC30 YNR030W ECM39 1.6 14 4.3 0.7169 0.211016606 iYNR029C 0.219911411 0.628683322 0.399720475 ECM39 -- cell wall biogenesis -- cell wall structure or biosynthesis YBR261C YBR261C 1.5 13 4.3 0.7169 0.193785454 iYBR261C 0.314948144 0.710774142 0.10814116 YBR261C -- unknown -- Putative S-adenosylmethionine-dependent methyltransferase of unknown role YHR081W YHR081W 1.5 12 4.3 0.7169 0.390179572 iYHR080C 0.513032216 0.452304222 0.187056438 YHR081W -- unknown -- unknown function YHR088W YHR088W 1.5 12 4.3 0.7169 0.303501335 iYHR087W 0.638756808 0.5792498 0.500960867 YHR088W -- unknown -- unknown function YHR201C PPX1 1.5 13 4.3 0.7169 0.530985009 iYHR201C 0.413266282 0.716964418 0.429337232 "PPX1 -- unknown -- Exopolyphosphatase, degrades polyphosphate with conversion of ADP to ATP" YJL200C YJL200C 1.5 12 4.3 0.7169 0.584879819 iYJL200C itT(AGU)J 0.783664282 0.767812134 0.810097834 0.696091173 0.653345725 "YJL200C -- unknown -- similarity to aconitase, has potential mitochondrial transit peptide" YBL004W YBL004W 1.3 12 4.3 0.7169 0.607173367 YBLWdelta10 iYBLWdelta10 0.772392844 0.561668832 0.490891755 0.799790525 0.595610535 "YBL004W -- unknown -- similarity to human DRIM, a protein differentially produced in metastatic and nonmetastatic human breast carcinoma cells" YJL011C YJL011C 1.3 12 4.3 0.7169 0.593366693 iYJL011C itK(CUU)J 0.421482921 0.633361658 0.545130575 0.98977722 YJL011C -- unknown -- RNA polymerase III subunit C17 YDR161W TCI1 1.2 11 4.3 0.7169 iYDR160W 0.717158513 0.456584198 TCI1 -- unknown -- interacts with protein phosphatase 2C YNL108C YNL108C 1.2 11 4.3 0.7169 0.282258169 iYNL108C 0.461378084 0.44567234 0.34616967 "YNL108C -- unknown -- similarity to RNA polymerase III transcription initiation factor TFIIIC tau subunit, Tfc7p" YHR041C SRB2 1.1 10 4.3 0.7169 0.585780473 iYHR041C 0.461805327 0.718063535 0.450996209 SRB2 -- transcription -- Component of RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex YJL133W MRS3 1.3 11 4.2 0.711 1 iYJL134W 0.980153545 0.187106918 "MRS3 -- transport -- Splicing protein and member of mitochondrial carrier (MCF) family, suppresses mitochondrial splicing defects" YLL026W HSP104 4.9 44 4.2 0.711 0.814666154 iYLL027W 0.496847242 0.642523364 0.379017846 "HSP104 -- heat shock response /thermotolerance -- Heat shock induced thermotolerance and for resolubilizing aggregates of denatured proteins, important for the [psi-] to [PSI+] prion conversion" YLR370C ARC18 2.9 26 4.2 0.711 0.422227845 iYLR370C 0.20265614 0.310295291 0.239265762 ARC18 -- cytoskeleton -- Component of ARP2/3 actin-organizing complexinvolved in actin assembly and function YFL018C LPD1 2.5 22 4.2 0.711 0.806171556 iYFL018C 0.376385277 0.941196062 0.30726257 "LPD1 -- TCA cycle -- Dihydrolipoamide dehydrogenase, (E3) component of pyruvate dehydrogenase complex, 2-oxoglutarate dehydrogenase complex, branched chain 2-oxoacid dehydrogenase complex, and glycine carboxylase complex" YLR257W YLR257W 2.5 22 4.2 0.711 0.557841679 iYLRWdelta14 YLRWdelta15 0.783816113 0.36533978 0.39481245 0.705088302 0.380333952 YLR257W -- unknown -- unknown function YHR065C RRP3 2.2 20 4.2 0.711 0.209292204 iYHR065C 0.765501052 0.66129552 0.436728395 RRP3 -- rRNA processing -- Helicase required for maturation of pre-rRNA YIL034C CAP2 2.2 20 4.2 0.711 0.129082357 iYIL034C 0.252966269 0.378898635 0.064289748 "CAP2 -- cytoskeleton -- Actin-capping protein, beta subunit" YPR159W KRE6 2.2 20 4.2 0.711 0.179497463 iYPR158W YPRCdelta22 0.488091587 0.503154391 0.359713487 0.720712474 0.373772057 "KRE6 -- cell wall biogenesis -- Glucan synthase subunit required for synthesis of beta-1,6-glucan" YBR146W MRPS9 2.1 19 4.2 0.711 0.580247994 iYBR145W 0.550691951 0.855462456 0.605100715 "MRPS9 -- protein synthesis -- Mitochondrial ribosomal small subunit S9, member of prokaryotic ribosomal protein S9 family" YJR017C ESS1 2 18 4.2 0.711 0.503016349 0.806969428 ESS1 -- protein folding -- Peptidylpropyl-cis/trans-isomeraseinvolved in transcription termination or 3'-end processing of pre-mRNA YBR137W YBR137W 1.9 17 4.2 0.711 0.197544228 iYBR136W 0.703758038 0.616552956 0.769912211 YBR137W -- unknown -- unknown function YKR006C MRPL13 1.9 17 4.2 0.711 0.665705198 iYKR006C 0.01777473 0.923610551 0.001117318 MRPL13 -- protein synthesis -- Mitochondrial ribosomal large subunit YLR079W SIC1 1.9 17 4.2 0.711 0.11415264 iYLR078C 0.261998553 0.05734243 0.15471485 SIC1 -- cell cycle -- P40 inhibitor of Cdc28p-Clb protein kinase complex YLR292C SEC72 1.9 17 4.2 0.711 0.650539547 iYLR292C 0.860639549 0.758540122 0.845633258 "SEC72 -- secretion -- Component of ER protein-translocation subcomplex that includes Sec62p, Sec63p, Sec66p, and Sec72p" YNL085W MKT1 1.9 17 4.2 0.711 0.206059951 iYNL086W 0.266135635 0.606846046 0.510820374 MKT1 -- viral propagation -- propagation of M2 double-stranded RNA (dsRNA) satellite of L-A virus at temperature above 30 deg YDR100W YDR100W 1.8 16 4.2 0.711 0.614882451 iYDR099W 0.739248311 0.319028797 0.424178896 YDR100W -- unknown -- unknown function YHR012W VPS29 1.8 16 4.2 0.711 0.510361017 iYHR011W 0.600492635 0.949826571 0.706656793 "VPS29 -- vacuolar protein targeting -- vacuolar sorting, mutant has vacuoles of normal morphology" YOR370C MRS6 1.8 16 4.2 0.711 0.916070995 iYOR370C 0.281103088 0.661793372 0.08727918 MRS6 -- protein processing -- Rab geranylgeranyltransferase regulatory component (component A) and rab guanine nucleotide dissociation inhibitor YPL145C KES1 1.7 15 4.2 0.711 0.914952007 iYPL145C YPL144W 0.976723293 0.933625264 0.72904735 0.202117888 0.60622506 "KES1 -- sterol metabolism -- implicated in ergosterol biosynthesis, member of KES1/HES1/OSH1/YKR003W family of oxysterol-binding (OSBP) proteins" YPL245W YPL245W 1.7 15 4.2 0.711 0.292536028 iYPL246C 0.078829945 0.522106943 0.045503168 YPL245W -- unknown -- unknown function YMR043W MCM1 1.6 14 4.2 0.711 0.080377286 iYMR042W 0.2516589 0.080896686 0.300879245 "MCM1 -- transcription -- Transcription factor of MADS (Mcm1p, Agamous, Deficiens, SRF) box family, recruits coregulatory proteins for both gene activation and repression at a variety of loci" YNL004W HRB1 1.5 13 4.2 0.711 0.174361362 iYNL005C 0.83130145 0.123267805 0.455977908 "HRB1 -- unknown -- similarity to Rlf6p, has 3 RNA recognition (RRM) domains" YDR267C YDR267C 1.3 12 4.2 0.711 0.313870158 iYDR267C 0.409901626 0.357701516 0.723217303 YDR267C -- unknown -- similarity to Sec13p and other proteins with WD (WD-40) repeats YLR051C YLR051C 1.3 11 4.2 0.711 0.30918224 iYLR051C 0.247953254 0.30993194 0.121593291 YLR051C -- unknown -- unknown function YNL207W YNL207W 1.3 12 4.2 0.711 0.485110335 iYNL208W 0.802610904 0.294231389 0.79785432 YNL207W -- unknown -- unknown function YOL147C PEX11 1.3 12 4.2 0.711 0.119943994 iYOL147C 0.146768227 0.54950997 0.117100372 PEX11 -- peroxisome biogenesis -- Peroxisomal biogenesis protein (peroxin) involved in peroxisome inheritance and peroxisomal proliferation YBR219C 1.1 10 4.2 0.711 0.404249583 0.688766597 YDL227C HO 1.1 10 4.2 0.711 0.744615892 iYDL227C-0 iYDL227C-1 0.482904434 0.709617406 0.390903632 0.693296089 0.915482841 "HO -- mating type switching -- Homothallic switching endonuclease, initiates mating type interconversion by making a double-stranded break in the expressed MAT gene" YBR155W CNS1 1 9 4.2 0.711 0.193832784 iYBR154C 0.740325109 0.200319234 0.474035395 "CNS1 -- unknown -- Component of Hsp90 chaperpne complex, has tetratricopeptide (TPR) repeats" YIL096C YIL096C 1 9 4.2 0.711 0.27551491 iYIL096C itI(AAU)I1 0.31027442 0.508074447 0.400641817 0.225870156 0.508853151 YIL096C -- unknown -- unknown function YLL039C UBI4 2.5 22 4.1 0.7033 1 0.897547077 iYLL039C 0.967851759 0.883650128 0.778508772 "UBI4 -- protein degradation, ubiquitin-mediated -- Ubiquitin polyprotein, mature ubiquitin is cleaved from polyubiquitin (Ubi4p) or from fusions with ribosomal proteins Rps31p, Rpl40Ap, or Rpl40Bp" YGL115W SNF4 2 18 4.1 0.7033 1 0.975556114 iYGL116W 0.984643384 0.936920223 0.056603774 "SNF4 -- glucose derepression -- derepression of glucose-repressed genes, acts with Snf1p" YDR300C PRO1 1.6 14 4.1 0.7033 1 0.968952516 iYDR300C 0.980802672 0.679338435 0.225183916 "PRO1 -- proline biosynthesis -- Glutamate 5-kinase, carries out first step in proline biosynthesis pathway" YMR008C PLB1 2.5 22 4.1 0.7033 0.310364866 iYMR008C 0.482848742 0.666048237 0.195133742 "PLB1 -- phospholipid metabolism -- Phospholipase B, preferentially deacylates phosphatidylcholine and phosphatidylethanolamine" YER050C YER050C 2.4 21 4.1 0.7033 0.538882994 iYER050C 0.770974514 0.723894543 0.784809057 YER050C -- unknown -- unknown function YPL178W CBC2 2.4 22 4.1 0.7033 0.314880622 iYPL179W tE(UUC)P 0.642184425 0.769245249 0.285075818 0.580367119 0.576630618 "CBC2 -- meiosis, recombination -- Small subunit of nuclear cap-binding protein complex" YBR073W RDH54 2.2 21 4.1 0.7033 0.618327549 iYBR072W 0.151528023 0.674897527 0.591536712 RDH54 -- meiosis -- mitotic diploid-specific recombination and repair and for meiosis YGR208W SER2 2.2 21 4.1 0.7033 0.633421969 iYGR207C 0.441993902 0.665243313 0.526564347 "SER2 -- glycine, serine, and threonine metabolism -- Phosphoserine phosphataseinvolved in synthesis of serine from 3-phosphoglycerate" YBR115C LYS2 2.1 19 4.1 0.7033 0.545663979 iYBR115C 0.773240237 0.593535515 0.780834073 "LYS2 -- lysine biosynthesis -- Alpha-aminoadipate-semialdehyde dehydrogenase large chain, sixth step in lysine biosynthesis pathway" YIL038C NOT3 2 18 4.1 0.7033 0.469726404 iYIL038C 0.625371814 0.724677034 0.560408922 "NOT3 -- transcription -- Component of CCR4 transcriptional complex, involved in transcriptional regulation" YLR351C NIT3 2 18 4.1 0.7033 0.764443327 iYLR351C 0.405853704 0.926362683 0.70351273 NIT3 -- unknown -- Nitrilase YDL052C SLC1 1.9 18 4.1 0.7033 0.488771584 iYDL052C 0.364492998 0.251624431 0.144882537 "SLC1 -- phospholipid metabolism -- Fatty acyltransferase (sn2-acylglyceride fatty acyltransferase), second step of phosphatidic acid synthesis" YOL005C RPB11 1.9 17 4.1 0.7033 0.267553047 iYOL005C 0.261649477 0.696987598 0.241421871 "RPB11 -- transcription -- RNA polymerase II, essential subunit, not shared" YIL070C MAM33 1.8 17 4.1 0.7033 0.641288214 iYIL070C 0.502356072 0.914285714 0.226089895 MAM33 -- respiration -- Mitochondrial normal respiratory growth YMR091C NPL6 1.8 16 4.1 0.7033 0.448723363 iYMR091C 0.642240803 0.531595192 0.511452242 NPL6 -- nuclear protein targeting -- Nuclear protein localization factor YPR051W MAK3 1.8 16 4.1 0.7033 0.207476947 0.482442348 "MAK3 -- viral propagation -- N-acetyltransferase, acetylates N-terminus of L-A virus GAG protein" YDR481C PHO8 1.7 15 4.1 0.7033 0.698578422 iYDR481C 0.269438092 0.939844542 0.273049931 "PHO8 -- phosphate metabolism -- Vacuolar alkaline phosphatase (ALP), repressible, carries out dephosphorylation of phosphopeptides" YGR076C MRPL25 1.7 16 4.1 0.7033 0.488879119 iYGR076C 0.394204306 0.630878438 0.485867446 MRPL25 -- protein synthesis -- Mitochondrial ribosomal large subunit YMR26 (YmL25) YGR173W YGR173W 1.7 15 4.1 0.7033 0.862621076 iYGR172C 0.357319183 0.932162423 0.370206252 YGR173W -- unknown -- similarity to human GTP-binding protein PIR YOL021C DIS3 1.7 15 4.1 0.7033 0.292569892 iYOL021C 0.327677194 0.652232459 0.528598603 "DIS3 -- RNA processing -- Ran-binding mitotic control, component of exosome 3'-5' exoribonuclease complex involved in 3' end processing of multiple small RNA species" YPL212C PUS1 1.7 15 4.1 0.7033 0.316231892 iYPL212C 0.598436977 0.370770222 0.483337448 PUS1 -- tRNA processing -- Pseudouridine synthase responsible for specific pseudouridine modifications in tRNA and in U2 snRNA YBR205W KTR3 1.6 14 4.1 0.7033 0.311188233 iYBR204C 0.509500273 0.653336625 0.800919577 "KTR3 -- protein glycosylation -- Alpha-1,2-mannosyltransferase of KRE2 family" YFR047C YFR047C 1.6 14 4.1 0.7033 0.222291028 iYFR047C 0.544852359 0.91027583 0.333508036 "YFR047C -- unknown -- Putative quinolinic acid phosphoribosyltransferase, active in the pathway of tryptophan degradation and nicotinic acid synthesis" YGR277C YGR277C 1.6 14 4.1 0.7033 0.214614973 iYGR277C 0.542159261 0.338574423 0.131524342 YGR277C -- unknown -- unknown function YLR078C BOS1 1.6 14 4.1 0.7033 0.736069235 iYLR078C 0.261998553 0.872582848 0.15471485 BOS1 -- secretion -- Synaptobrevin (v-SNARE) homologinvolved in ER to Golgi transport YML048W GSF2 1.6 14 4.1 0.7033 0.708440155 iYML049C 0.601116415 0.841181165 0.540223464 "GSF2 -- glucose repression -- glucose repression, also possibly involved in cell wall structure or biosynthesis" YNL315C ATP11 1.6 15 4.1 0.7033 0.633249864 iYNL315C 0.448145189 0.883762201 0.477441703 ATP11 -- ATP synthesis -- F1-ATP synthase assembly protein YDR512C YDR512C 1.5 13 4.1 0.7033 0.149000882 0.162182177 YDR512C -- unknown -- unknown functionquestionable ORF YJL183W MNN11 1.5 13 4.1 0.7033 0.517124008 iYJL184W 0.130391671 0.791411537 0.248538012 MNN11 -- unknown -- Subunit of Anp1p-Hoc1p-Mnn10-Mnn11p-Mnn9p mannosyltransferase complex YPR137W RRP9 1.5 13 4.1 0.7033 0.250651051 0.345387841 "RRP9 -- rRNA processing -- associated with the U3 small nucleolar RNA, required for pre-ribosomal RNA processing" YKL001C MET14 1.3 12 4.1 0.7033 0.696388711 iYKL001C CEN11 0.598715805 0.664723148 0.938387869 0.942647415 0.406304868 "MET14 -- sulfate assimilation -- Adenosine-5'-phosphosulfate 3'-phosphotransferase (adenylylsulfate kinase), part of sulfate assimilation pathway" YLR188W MDL1 1.3 13 4.1 0.7033 0.163822808 iYLR187W 0.340118125 0.461401952 0.256674552 "MDL1 -- transport -- Member of ATP-binding cassette (ABC) superfamily, equivalent to a ""half-sized"" ABC one ATP-binding domain and one transmembrane domain" YNR015W SMM1 1.3 12 4.1 0.7033 0.294943042 iYNR014W 0.114953993 0.681759587 0.100389864 "SMM1 -- protein synthesis, mitochondrial (putative) -- High-copy suppressor of mitochondrial mutation in tRNA(asp) gene" YOL149W DCP1 1.3 12 4.1 0.7033 0.553488397 iYOL150C 0.285022045 0.862508735 0.343043481 DCP1 -- mRNA decay -- mRNA decapping enzyme involved in mRNA turnover YDR044W HEM13 1.2 11 4.1 0.7033 0.592235112 iYDR043C-0 iYDR043C-1 0.37678677 0.30698206 0.503383179 0.329945269 0.797566746 "HEM13 -- heme biosynthesis -- Coproporphyrinogen III oxidase, oxygen-repressed, sixth step in heme biosynthetic pathway" YNL240C NAR1 1.2 11 4.1 0.7033 0.614760029 iYNL240C 0.157910853 0.884165772 0.182814799 NAR1 -- nuclear organization and biogenesis (putative) -- similarity to human nuclear prelamin A recognition factor YPL126W NAN1 1.2 11 4.1 0.7033 0.455101085 iYPL127C 0.044362566 0.307914046 0.111083683 NAN1 -- unknown -- Nucleolar protein associated with Net1p YPR183W DPM1 1.2 11 4.1 0.7033 0.316361604 iYPR182W 0.763976463 0.70810506 0.363291137 DPM1 -- protein glycosylation -- Dolichol-phosphate mannosyltransferasetransfers mannose from GDP-Man to Dol-P YHR148W IMP3 1.1 10 4.1 0.7033 0.238566101 iYHR147C 0.160191031 0.600107116 0.439864483 "IMP3 -- rRNA processing -- Component of U3 snoRNP, required for pre-18S rRNA processing" YEL056W HAT2 1.5 14 4 0.6982 1 0.91996741 iYEL057C 0.959510459 0.480606544 0.8471668 "HAT2 -- chromatin structure -- Histone acetyltransferase subunit 2, contains seven WD (WD-40) repeats" YOR125C CAT5 1.5 13 4 0.6982 1 0.982203059 iYOR125C 0.743637037 0.821327741 0.502274722 CAT5 -- ubiquinone biosynthesis -- derepression of gluconeogenic enzymes and for coenzyme Q (ubiquinone) biosynthesis YCL035C GRX1 5.1 47 4 0.6982 0.349851103 iYCL035C 0.128573789 0.034503843 0.113993711 "GRX1 -- oxidative stress response -- Putative glutaredoxin, has similarity to thioltransferase Ttr1p" YOR157C PUP1 3.5 32 4 0.6982 0.374426417 iYOR157C 0.40757311 0.522579597 0.491702055 "PUP1 -- protein degradation -- Proteasome subunit beta2_sc (protease yscE subunit PUP1), involved in trypsin-like activity of proteasome" YLR037C YLR037C 3 28 4 0.6982 0.871202221 iYLR037C-0 iYLR037C-1 0.351101766 0.428568807 0.678861102 0.421558351 0.224701901 YLR037C -- unknown -- Member of seripauperin (PAU) family YBR149W ARA1 2.5 24 4 0.6982 0.274124876 iYBR148W 0.587739135 0.817918144 0.622745411 ARA1 -- arabinose metabolism -- Subunit of NADP+-dependent D-arabinose dehydrogenase YDL173W YDL173W 2.2 21 4 0.6982 0.228705151 iYDL174C 0.190036226 0.519561184 0.188271605 YDL173W -- unknown -- unknown function YNL037C IDH1 2 19 4 0.6982 0.446951428 iYNL037C 0.722587462 "IDH1 -- TCA cycle -- Isocitrate dehydrogenase (NAD+) subunit 1, mitochondrial, required for oxidative function of tricarboxylic acid cycle" YER083C YER083C 1.9 18 4 0.6982 0.571126611 0.875977654 YER083C -- unknown -- unknown function YML030W YML030W 1.9 18 4 0.6982 0.352761476 iYML031W 0.412432342 0.303818885 0.125887124 YML030W -- unknown -- unknown function YBL036C YBL036C 1.8 17 4 0.6982 0.403892565 iYBL036C 0.349735527 0.764405427 0.12240091 YBL036C -- unknown -- similarity to Pseudomonas aeroginosa twitching motility protein YCL002C YCL002C 1.8 17 4 0.6982 0.652581177 iYCL002C 0.194936938 0.667747678 0.418826627 YCL002C -- unknown -- unknown function YER107C GLE2 1.7 16 4 0.6982 0.746949055 iYER107C iYER108C 0.317862763 0.13198534 0.9767645 0.345640419 0.117609099 "GLE2 -- nuclear protein targeting -- Nuclear pore poly(A)+ RNA export, has WD (WD-40) repeats" YKL186C MTR2 1.7 15 4 0.6982 0.305334475 iYKL186C 0.441512475 0.561213089 0.3896249 "MTR2 -- mRNA export -- mRNA transport, has similarity to E. coli mbeA" YEL050C RML2 1.5 14 4 0.6982 0.513198458 iYEL050C SNR67 0.716215544 0.84668702 0.582983625 0.705538085 0.6632083 RML2 -- protein synthesis -- Mitochondrial ribosomal protein L2 of large subunit YHR060W VMA22 1.5 13 4 0.6982 0.254576787 iYHR059W 0.433461253 0.240143655 0.190502793 "VMA22 -- vacuolar acidification -- vacuolar H(+)-ATPase (V-ATPase) assembly or function, essential for V-ATPase activity" YLR147C SMD3 1.5 14 4 0.6982 0.154578603 iYLR147C 0.299166727 0.230229807 0.179194503 "SMD3 -- mRNA splicing -- Spliceosomal snRNA-associated Sm core pre-mRNA splicing, also associated with telomerase TLC1 RNA" YFR011C YFR011C 1.3 13 4 0.6982 0.527344844 iYFR011C itY(GUA)F1 0.708943017 0.77874145 0.699138222 0.252980986 0.690219143 YFR011C -- unknown -- unknown function YHL049C YHL049C 1.3 12 4 0.6982 0.972803169 iYHL049C-0 iYHL049C-1 0.995609492 0.995478522 0.876902822 0.017238627 0.269654088 "YHL049C -- unknown -- similarity to other subtelomerically-encoded proteins including Yer189p, Yml133p, and Yjl225p, coded from a subtelomeric Y' region" YOR165W YOR165W 1.3 13 4 0.6982 0.203406854 iYOR164C 0.480636519 0.434298621 0.544063194 "YOR165W -- unknown -- similarity in the C-terminal region to human GBP1, an interferon-induced GTP-binding protein" YBL054W YBL054W 1.2 12 4 0.6982 0.263447146 iYBL055C 0.628223746 0.490895907 0.78754988 YBL054W -- unknown -- unknown function YDR017C KCS1 1.2 12 4 0.6982 0.649707752 iYDR017C 0.796716759 0.279888268 0.667940951 "KCS1 -- cell wall organization -- Inositol (1,2,3,4,5,6) hexaphosphate kinase, suppressor of temperature-sensitive growth and hyperrecombination in pkc1-4" YDR201W SPC19 1.2 11 4 0.6982 0.290492815 iYDR200C 0.227409272 0.633298393 0.07443393 SPC19 -- cytoskeleton -- spindle pole body YMR158W YMR158W 1.2 11 4 0.6982 0.627220838 iYMR157C 0.58225271 0.869470911 0.488989272 YMR158W -- unknown -- weak similarity to E. coli ribosomal protein S8 YOR098C NUP1 1.2 12 4 0.6982 0.39176198 iYOR098C 0.426588612 0.283630328 0.736595167 NUP1 -- nuclear protein targeting -- Nuclear pore protein (nucleoporin) with XFXFG motifsrelated to Nsp1p YOL080C REX4 0.8 8 4 0.6982 0.240308617 0.219972574 "REX4 -- unknown -- Member of 3' -to 5' exonuclease family, has similarity to Rnh70p and Pan2p" YOR383C YOR383C 5.4 51 3.9 0.6936 0.140494822 iYOR383C 0.299554502 0.122139865 0.082442139 YOR383C -- unknown -- unknown function YCR004C YCP4 4.6 43 3.9 0.6936 0.766436324 iYCR004C 0.656667159 0.955634428 0.635594573 YCP4 -- unknown -- similarity to S. pombe brefeldin A resistance protein obr1 and E. coli WrbA protein which stimulates binding of Trp repressor to DNA YLL028W TPO1 2.7 25 3.9 0.6936 0.833185947 iYLL029W 0.465194042 0.701659684 0.798897392 "TPO1 -- transport -- Polyamine transport protein, member of multidrug-resistance 12-spanner family of major facilitator superfamily (MFS-MDR)" YCR084C TUP1 2.1 21 3.9 0.6936 0.101966617 iYCR084C 0.310011711 0.230100715 0.10001747 "TUP1 -- transcription -- General repressor of RNA polymerase II transcription that is brought to target promoters by regulated, sequence-specific DNA-binding proteins, has seven WD repeats, exists in a complex with Ssn6p" YPR004C YPR004C 2 19 3.9 0.6936 0.32366551 iYPR004C 0.361565269 0.667455221 0.353689977 YPR004C -- unknown -- Electron transfer flavoprotein alpha subunit YNL123W YNL123W 1.9 18 3.9 0.6936 0.122924404 iYNL124W 0.217823003 0.411572227 0.056316468 "YNL123W -- unknown -- unknown function, has possible serine protease domain" YNL229C URE2 1.8 17 3.9 0.6936 0.210612986 iYNL229C 0.23403912 0.420220204 0.293103448 URE2 -- catabolite repression -- Regulator of nitrogen catabolite repressionacts by inhibition of Gln3p regulator in the presence of preferred nitrogen sources YOR047C STD1 1.8 17 3.9 0.6936 iYOR047C 0.569568886 0.727676051 STD1 -- glucose repression -- Dosage-dependent modulator of glucose repressionincreased dosage restores invertase expression in snf4 mutants YDL178W AIP2 1.7 16 3.9 0.6936 0.298765466 iYDL179W 0.386096567 0.466369672 0.344552638 AIP2 -- unknown -- D-lactate dehydrogenase YNR041C COQ2 1.7 16 3.9 0.6936 0.640334497 0.296383913 "COQ2 -- ubiquinone biosynthesis -- Para-hydroxybenzoate--polyprenyltransferase, second step in coenzyme Q (ubiquinone) biosynthesis pathway" YCR057C 1.6 15 3.9 0.6936 0.514782751 iYCR057C 0.516900673 0.669378866 0.559856345 YOL051W GAL11 1.6 15 3.9 0.6936 0.313400469 iYOL052C 0.724410666 0.198598131 0.5896249 GAL11 -- transcription -- Component of RNA polymerase II holoenzyme and Kornberg's mediator complex with positive and negative effects on transcription of individual genes YER152C YER152C 1.5 14 3.9 0.6936 0.530036577 0.88292099 YER152C -- unknown -- unknown function YOL142W RRP40 1.5 14 3.9 0.6936 0.157823562 iYOL143C 0.072553962 0.741916808 0.307493748 "RRP40 -- rRNA processing -- ribosomal RNA processing, component of exosome complex responsible for 3' end processing and degradation of many RNA species" YHL039W YHL039W 1.3 12 3.9 0.6936 0.630795328 iYHL040C 0.347111402 0.73622301 0.598619846 YHL039W -- unknown -- weak similarity to protein lysine methyltransferases YNL180C RHO5 1.3 13 3.9 0.6936 0.245247165 0.567596478 RHO5 -- signaling -- unknown function member of rho family in the ras superfamily YOL004W SIN3 1.3 13 3.9 0.6936 0.222078752 iYOL005C 0.261649477 0.328947368 0.241421871 SIN3 -- transcription -- Transcriptional regulator of RNA polymerase IIhas negative and positive effects on individual gene expression YML116W ATR1 1.2 12 3.9 0.6936 0.261497885 iYML117W-A 0.859175776 0.378057303 0.786862334 "ATR1 -- aminotriazole resistance -- Membrane transporter conferring aminotriazole and 4-nitroquinoline-1-oxide (4NQO) resistance, member of multidrug-resistance 14-spanner family of major facilitator superfamily (MFS-MDR)" YNL022C YNL022C 1.2 12 3.9 0.6936 0.206605204 iYNL022C 0.590932705 0.464092599 0.232342007 YNL022C -- unknown -- unknown function YOL019W YOL019W 1.2 11 3.9 0.6936 0.128748756 iYOL020W itY(GUA)O 0.602775202 0.53109438 0.143248469 0.491354706 0.802682465 YOL019W -- unknown -- unknown function YIL004C BET1 1.1 10 3.9 0.6936 0.474784014 iYIL004C 0.54978259 0.724653599 0.729938769 BET1 -- secretion -- Synaptobrevin (v-SNARE) homologpresent on ER vesicles recycling from Golgi YDR021W FAL1 0.9 9 3.9 0.6936 0.641664217 iYDR020C 0.433498885 0.60415004 0.419069456 FAL1 -- rRNA processing -- Putative ATP-dependent RNA helicase with similarity to eukaryotic initiation factor 4A subfamily of DEAD-box proteins YGR206W YGR206W 0.9 9 3.9 0.6936 0.801683053 iYGR205W 0.581835843 0.78013213 0.567503778 YGR206W -- unknown -- unknown function YDL188C PPH22 1.8 17 3.8 0.6867 1 0.891775595 iYDL188C 0.990657068 0.714018843 0.905376868 "PPH22 -- cell cycle -- Protein serine/threonine phosphatase PP2A-2, highly homologous to Pph21p, member of PPP family of protein phosphatases" YOR101W RAS1 1 10 3.8 0.6867 1 0.690904253 iYOR100C 0.957059997 0.442365088 0.14051332 "RAS1 -- signaling, Ras pathway -- GTP-binding regulation of cAMP pathway, homolog of mammalian proto-oncogene ras" YCL040W GLK1 3.7 36 3.8 0.6867 0.83854991 0.967819424 "GLK1 -- glycolysis -- Glucokinase, specific for aldohexoses" YKR014C YPT52 3.1 31 3.8 0.6867 0.118039155 iYKR014C 0.275882176 0.129050279 0.540534 YPT52 -- endocytosis -- GTP-binding rab family (ras superfamily) involved in endocytosis and transport of proteins to the vacuole YBL045C COR1 2.8 27 3.8 0.6867 0.718181199 iYBL045C 0.759867416 0.917032781 0.514985498 "COR1 -- oxidative phosphorylation -- Ubiquinol cytochrome-c reductase core protein 1, component of ubiquinol cytochrome-c reductase complex" YGR235C YGR235C 2.5 24 3.8 0.6867 0.594924501 iYGR235C 0.648545193 0.538759377 0.695496274 YGR235C -- unknown -- unknown function YOR360C PDE2 2.4 23 3.8 0.6867 0.880767377 iYOR360C 0.486296039 0.907074292 0.522642785 "PDE2 -- signaling (putative) -- 3',5'-Cyclic-nucleotide phosphodiesterase, high-affinity" YMR092C AIP1 2.1 20 3.8 0.6867 0.819371739 iYMR092C 0.898791799 0.748003549 0.098850963 "AIP1 -- cytoskeleton -- Actin interacting protein, contains four WD (WD-40) repeats" YAR073W YAR073W 1.8 18 3.8 0.6867 0.976319121 iYAR071W 0.85967054 0.500974659 0.39709993 "YAR073W -- unknown -- strong similarity to inosine-5'-monophosphate dehydrogenase, frameshifted from YAR075W, possible pseudogene" YBR230C YBR230C 1.8 18 3.8 0.6867 0.090129103 iYBR230C LSR1 0.066963352 0.893120389 0.172433398 0.007512229 0.094700331 YBR230C -- unknown -- unknown function YGR033C YGR033C 1.7 16 3.8 0.6867 iYGR033C 0.987378407 0.278131806 YGR033C -- unknown -- unknown function YNR055C HOL1 1.7 17 3.8 0.6867 0.322974124 iYNR055C 0.318221577 0.514061508 0.553443594 "HOL1 -- transport -- Membrane transporter, member of multidrug-resistance 12-spanner family of major facilitator superfamily (MFS-MDR)" YOR086C YOR086C 1.7 16 3.8 0.6867 0.174875562 iYOR086C itN(GUU)O2 0.759457355 0.644670068 0.170402859 0.491041404 0.495557645 YOR086C -- unknown -- unknown function YOR123C LEO1 1.7 16 3.8 0.6867 0.119549737 iYOR123C 0.17905721 0.024820431 0.141081871 "LEO1 -- unknown -- unknown function, extremely hydrophilic" YJL004C SYS1 1.6 15 3.8 0.6867 0.40533805 iYJL004C 0.440914259 0.710171816 0.73565904 SYS1 -- secretion (putative) -- Multicopy suppressor of ypt6 null mutation YNL221C POP1 1.6 15 3.8 0.6867 0.432089754 iYNL221C 0.03292043 0.58315863 0.133629556 "POP1 -- rRNA and tRNA processing -- component of both RNase P and RNase MRP, involved in both tRNA maturation (RNase P) and in 5.8S rRNA processing (RNase MRP)" YNL241C ZWF1 1.6 16 3.8 0.6867 0.598130912 iYNL241C 0.488159089 0.76836995 0.411214953 ZWF1 -- pentose phosphate cycle -- Glucose-6-phosphate dehydrogenase YDR347W MRP1 1.5 15 3.8 0.6867 0.274032511 iYDR346C 0.197126888 0.718834856 0.192007797 MRP1 -- protein synthesis -- Mitochondrial ribosomal small subunit YNL088W TOP2 1.5 14 3.8 0.6867 0.298165514 iYNL089C 0.302978792 0.307251754 0.288134226 "TOP2 -- DNA replication -- DNA topoisomerase II, hydrolyzes ATP to make double-stranded breaks in DNA" YNL219C ALG9 1.5 14 3.8 0.6867 0.361421402 iYNL219C 0.498269551 0.567434315 0.686408106 "ALG9 -- protein glycosylation -- Mannosyltransferase involved in N-glycosylation, catalyzes transfer of mannose from Dol-P-Man to lipid-linked oligosaccharides" YDL070W BDF2 1.3 13 3.8 0.6867 0.587539394 0.428439186 BDF2 -- unknown -- Bromodomain affects telomere function YHL025W SNF6 1.3 13 3.8 0.6867 0.775971615 iYHL026C 0.100743248 0.826754386 0.015634 "SNF6 -- transcription -- Component of SWI-SNF global transcription activator complex, acts to assist gene-specific activators through chromatin remodeling" YJR133W XPT1 1.3 13 3.8 0.6867 0.637658421 iYJR132W 0.431331066 0.745664274 0.23025856 XPT1 -- xanthine utilization -- Xanthine phosphoribosyl transferase YML010W-B 1.3 14.5 3.8 0.6867 YMR112C MED11 1.3 13 3.8 0.6867 0.34964064 iYMR112C 0.298669045 0.192762345 0.492635563 MED11 -- transcription -- Component of RNA polymerase II mediator (SRB) subcomplex YMR128W ECM16 1.3 13 3.8 0.6867 0.658368506 iYMR127C 0.860523065 0.38945744 0.607422187 ECM16 -- cell wall biogenesis -- Protein possibly involved in cell wall structure or biosynthesis YLR198C YLR198C 1.2 12 3.8 0.6867 0.334367854 iYLR198C 0.512344388 0.293535515 0.148635478 YLR198C -- unknown -- unknown function YNL206C RTT106 1.2 12 3.8 0.6867 0.494546199 0.390183559 RTT106 -- unknown -- similarity to SSRP proteins YIL065C YIL065C 1.1 11 3.8 0.6867 0.47464186 iYIL065C 0.494430234 0.674142059 0.710119239 YIL065C -- unknown -- unknown function YIL114C POR2 1.1 11 3.8 0.6867 0.650665087 iYIL114C 0.593536458 0.966542887 0.879723672 POR2 -- mitochondrial transport -- Outer mitochondrial membrane porinvoltage-dependent anion-selective channel YJR124C YJR124C 1 10 3.8 0.6867 0.810955456 iYJR124C 0.512540816 0.788005248 0.616036138 YJR124C -- unknown -- Member of multidrug-resistance 12-spanner family of major facilitator superfamily (MFS-MDR) YJL078C PRY3 0.9 9 3.8 0.6867 0.395247554 iYJL078C 0.880912545 0.254350628 0.71728972 "PRY3 -- unknown -- similarity to plant pathenogenesis-related proteins, may have a role in mating efficiency" YOL101C YOL101C 0.9 9 3.8 0.6867 0.108943285 iYOL101C 0.277357888 0.37240091 0.578285069 YOL101C -- unknown -- unknown function YPL039W YPL039W 0.9 9 3.8 0.6867 0.478773019 iYPL040C 0.281074117 0.5471668 0.220439398 YPL039W -- unknown -- unknown function YPR147C YPR147C 0.9 9 3.8 0.6867 0.316541782 iYPR147C 0.180078784 0.479648843 0.510984942 YPR147C -- unknown -- unknown function YOR359W YOR359W 1.6 15 3.7 0.6808 1 0.726474392 iYOR358W 0.930468764 0.306624102 0.325025346 YOR359W -- unknown -- unknown function YJL096W MRPL49 1.2 13 3.7 0.6808 1 0.972984949 0.784643893 MRPL49 -- protein synthesis -- Mitochondrial ribosomal large subunit (YmL49) YHR008C SOD2 2.4 24 3.7 0.6808 0.772961469 iYHR008C 0.387086886 0.680992313 0.217801276 "SOD2 -- oxidative stress response -- Manganese superoxide dismutase, mitochondrial" YBR160W CDC28 2.2 23 3.7 0.6808 0.200513888 iYBR159W 0.37666955 0.629991127 0.303783173 "CDC28 -- cell cycle -- Cyclin-dependent protein kinase essential for completion of START and for mitosis, associates with Cks1p and cyclins" YNL287W SEC21 2.2 22 3.7 0.6808 0.443232524 iYNL288W 0.51325635 0.852061507 0.091020266 SEC21 -- secretion -- Coatomer (COPI) complex gamma chain (gamma-COP) of secretory pathway vesiclesrequired for retrograde Golgi to endoplasmic reticulum transport YDR196C YDR196C 2.1 21 3.7 0.6808 0.3663405 iYDR196C 0.398655905 0.830823582 0.239977414 YDR196C -- unknown -- unknown function YNL130C CPT1 2.1 21 3.7 0.6808 0.313236109 iYNL130C 0.079974097 0.713775179 0.332487195 "CPT1 -- phospholipid metabolism -- sn-1,2-Diacylglycerol cholinephosphotransferasecatalyzes the synthesis of phosphatidylcholine from CDP-choline and diacylglycerol" YFL006W YFL006W 1.9 19 3.7 0.6808 0.405675494 iYFL007W 0.364335438 0.873619233 0.221174004 YFL006W -- unknown -- unknown function YOR052C YOR052C 1.8 18 3.7 0.6808 0.095954647 iYOR052C 0.068335174 0.101998066 0.029175402 YOR052C -- unknown -- unknown function YGR158C MTR3 1.6 16 3.7 0.6808 0.862444499 iYGR158C 0.65958837 0.890106349 0.774411859 "MTR3 -- mRNA transport -- mRNA transport, component of exosome complex responsible for 3'-5' degradation of mRNA and for 3'-end processing of multiple small RNA species" YLR384C IKI3 1.6 15 3.7 0.6808 0.388565006 iYLR384C 0.261460891 0.22851153 0.445339962 "IKI3 -- killer toxin sensitivity -- Component of elongator complex, associated with RNA Polymerase II during transcriptional elongation" YGR054W YGR054W 1.5 15 3.7 0.6808 0.624089364 iYGR053C 0.483706469 0.923115918 0.750431992 "YGR054W -- unknown -- possible role in signal transduction, has significant similarity to C. elegans E04D5.1 protein" YJR032W CPR7 1.5 14 3.7 0.6808 0.363935696 iYJR031C 0.392373739 0.622059967 0.170159194 "CPR7 -- protein folding -- Cyclophilin (peptidylprolyl cis-trans isomerase or PPIase), homolog of mammalian cyclophilin Cyp40" YBR185C MBA1 1.3 13 3.7 0.6808 0.562688063 iYBR185C 0.339734032 0.81629979 0.107045387 MBA1 -- respiration -- the assembly of mitochondrial respiratory complexes YJR060W CBF1 1.3 14 3.7 0.6808 0.489611965 iYJR059W 0.312285972 0.541819633 0.034241789 "CBF1 -- mitosis -- Basic helix-loop-helix (bHLH) kinetochore protein which binds to centromeric element CDE I, required for chromosome stability and for methionine prototrophy" YLR335W NUP2 1.3 14 3.7 0.6808 0.639484451 iYLRWdelta20 itE(UUC)L 0.931203095 0.793918361 0.540131801 0.518373824 0.66419295 NUP2 -- nuclear protein targeting -- Nuclear pore protein (nucleoporin) with XFXFG motifshas functional overlap with other proteins of nuclear pore complex YOL130W ALR1 1.3 14 3.7 0.6808 0.681006127 iYOL131W 0.645941715 0.762166272 0.819931774 "ALR1 -- aluminum resistance -- Putative cytoplasmic magnesium and cobalt transporter, member of metal ion transporter family of membrane transporters" YOR016C ERP4 1.3 14 3.7 0.6808 0.254429272 iYOR016C 0.045248503 0.156189084 0.035275339 ERP4 -- membrane trafficking; secretion (putative) -- similarity to COPII-coated vesicle proteins Emp24p and Erv25p YPL019C PHM2 1.3 14 3.7 0.6808 0.550147011 iYPL019C 0.773113362 0.572396548 0.740009747 PHM2 -- unknown -- Putative polyphosphate synthetase YBR015C MNN2 1.2 12 3.7 0.6808 0.729739146 iYBR015C 0.348277517 0.877470356 0.30782976 MNN2 -- protein glycosylation -- Mannosyltransferase required for forming and extending the mannose branches of outer chain mannans YDL144C YDL144C 1.2 13 3.7 0.6808 0.458506668 iYDL144C 0.262360483 0.58254717 0.503898635 YDL144C -- unknown -- unknown function YDL237W YDL237W 1.2 13 3.7 0.6808 0.242159425 iYDL238C 0.594176005 0.574236517 0.811728644 YDL237W -- unknown -- unknown function YKL068W NUP100 1.2 13 3.7 0.6808 0.325597899 iYKL069W itV(AAC)K1-0 0.505198127 0.670412009 0.603554678 0.30057652 0.933073424 NUP100 -- nuclear protein targeting -- Nuclear pore protein (nucleoporin) of GLFG familymay be involved in binding and translocation of proteins during nucleocytoplasmic transport YPR125W YPR125W 1.2 13 3.7 0.6808 0.524027848 iYPR124W 0.350892026 0.581834315 0.349923369 YPR125W -- unknown -- Suppressor of mrs2-1 mutation YPR139C YPR139C 1.2 12 3.7 0.6808 0.265586019 iYPR139C 0.17880289 0.532543405 0.050173429 YPR139C -- unknown -- unknown function YLL022C HIF1 1.1 11 3.7 0.6808 0.260317079 iYLL022C 0.078223236 0.522980737 0.340063847 "HIF1 -- chromatin structure -- interacts with histone acetyltransferase, Hat1p" YMR006C PLB2 1.1 11 3.7 0.6808 0.260609417 iYMR006C 0.304412494 0.329712828 0.549145988 "PLB2 -- phospholipid metabolism -- Phospholipase B2 (lysophospholipase), releases fatty acids from lysophospholipids" YJR067C YAE1 1 11 3.7 0.6808 0.591458959 iYJR067C 0.315289932 0.643087335 0.175759072 YAE1 -- unknown -- Essential unknown function YML115C VAN1 1 11 3.7 0.6808 0.642013024 iYML115C 0.753632903 0.803254915 0.648646425 "VAN1 -- protein glycosylation and vanadate resistance -- Vanadate resistance proteincomponent of mannan polymerase M-Pol I, which includes Mnn9p and Van1p" YNL182C YNL182C 0.8 8 3.7 0.6808 0.430065262 iYNL182C 0.441682709 0.809257781 0.491977923 YNL182C -- unknown -- unknown function YDL168W SFA1 2.9 30 3.6 0.6737 1 0.941243507 iYDL169C 0.962482739 0.359975542 0.820590583 SFA1 -- formaldehyde metabolism -- Long-chain alcohol dehydrogenase (ADH) with similarity to mammalian ADH class III YNL288W YNL288W 1.6 16 3.6 0.6737 1 0.963832758 iYNL289W-0 iYNL289W-1 0.957784362 0.990701204 0.823586352 0.588219885 0.749294184 YNL288W -- unknown -- unknown function YKR068C BET3 2.5 26 3.6 0.6737 0.171810742 iYKR068C 0.181868448 0.384665367 0.521269739 BET3 -- secretion -- Low molecular weight subunit of Transport Protein Particle (TRAPP) complex that is involved in targeting and fusion of ER to Golgi transport vesicleshydrophilic acts in conjunction with SNARE proteins YOL133W HRT1 2.5 26 3.6 0.6737 0.703063584 0.625684821 HRT1 -- unknown -- Activator of Cdc53p-containing SCF-Cdc4p ubiquitin ligase required for ubiquitination of Sic1p and for the G1 to S cell cycle transitionRING-box protein YGR172C YIP1 1.9 19 3.6 0.6737 0.177592439 iYGR172C 0.357319183 0.757075472 0.370206252 YIP1 -- unknown -- vesicular transportinteracts with transport GTPases Ypt1p and Ypt31p at the Golgi membrane YBR087W RFC5 1.8 19 3.6 0.6737 0.569676518 iYBR086C 0.643744418 0.863999355 0.630765808 "RFC5 -- DNA replication -- Replication factor C, 40 kDa subunit" YBR041W FAT1 1.7 17 3.6 0.6737 0.711455918 iYBR040W 0.851923837 0.488256168 0.903346329 FAT1 -- transport -- Very long-chain acyl-CoA synthetase (VLCS) YKL125W RRN3 1.7 17 3.6 0.6737 0.135514791 iYKL126W 0.347087483 0.34612929 0.599661208 RRN3 -- transcription -- RNA polymerase I transcription factor YNL084C END3 1.7 17 3.6 0.6737 0.65713819 iYNL084C 0.104502111 0.813987255 0.06645209 END3 -- endocytosis -- endocytosis and cytoskeletal organization YIL063C YRB2 1.6 17 3.6 0.6737 0.116041393 iYIL063C 0.69193691 0.137995452 0.224900239 YRB2 -- nuclear export -- Nuclear transport factor similar to Yrb1p and Nup2p YJR075W HOC1 1.6 16 3.6 0.6737 0.445412309 iYJR074W 0.344791698 0.725795971 0.146219041 HOC1 -- protein glycosylation -- Subunit of Anp1p-Hoc1p-Mnn11p-Mnn9p mannosyltransferase complex of Golgi involved in cell wall integrity YPL032C SVL3 1.6 16 3.6 0.6737 0.383034217 iYPL032C 0.27960447 0.24660814 0.215938872 SVL3 -- unknown -- vacuolar uptake of endocytosed vital dyes YBL085W BOI1 1.5 15 3.6 0.6737 0.523176519 iYBL086C 0.885386609 0.259524397 0.733120511 "BOI1 -- bud growth -- Bem1p-binding protein, has an SH3 domain and a PH (pleckstrin) domain" YBR276C PPS1 1.5 15 3.6 0.6737 0.323700826 iYBR276C 0.505658246 0.496571751 PPS1 -- unknown -- Protein tyrosine phosphatase (PTPase) with dual specificity YKL063C YKL063C 1.5 15 3.6 0.6737 0.374443451 iYKL063C-0 iYKL063C-1 0.450425784 0.905779505 0.175357375 0.213450292 YKL063C -- unknown -- unknown function YOR281C PLP2 1.5 15 3.6 0.6737 0.124520628 0.306530214 "PLP2 -- unknown -- Phosducin homologue, essential protein likely to be involved in regulation of pheromone response" YCR059C YCR059C 1.3 14 3.6 0.6737 0.513982603 iYCR059C 0.445807086 0.880112428 0.534553972 "YCR059C -- unknown -- unknown function, has similarity to mouse Impact protein" YFL018W-A SMX2 1.3 14 3.6 0.6737 "SMX2 -- -- Spliceosomal snRNA-associated Sm core protein, also likely associated with telomerase TLC1 RNA" YKR024C DBP7 1.3 14 3.6 0.6737 iYKR024C 0.516756351 0.578911795 DBP7 -- ribosome biogenesis -- Member of Dead-box family of putative RNA helicases and involved in 60S ribosomal large subunit biogenesis YOR251C YOR251C 1.3 13 3.6 0.6737 0.108729726 iYOR251C 0.315101262 0.467209152 0.206896552 "YOR251C -- unknown -- Rhodanese (thiosulfate sulfurtransferase), functions to detoxify cyanide" YPL030W YPL030W 1.3 14 3.6 0.6737 0.542423775 iYPL031C 0.156765013 0.429012346 0.201926326 YPL030W -- unknown -- unknown function YHR032W YHR032W 1.2 13 3.6 0.6737 0.910030121 iYHR031C 0.509132268 0.580808895 0.261220066 YHR032W -- unknown -- Member of multiple antimicrobiotic resistance (MAR) family of membrane transporters YNL050C YNL050C 1.2 12 3.6 0.6737 0.217850633 iYNL050C 0.500179299 YNL050C -- unknown -- unknown function YOL057W YOL057W 1.2 12 3.6 0.6737 0.393605144 iYOL058W 0.502007031 0.75982781 0.493264499 YOL057W -- unknown -- unknown function YOL146W YOL146W 1.2 13 3.6 0.6737 0.360757034 iYOL147C 0.146768227 0.811233403 0.117100372 YOL146W -- unknown -- unknown function YOR106W VAM3 1.2 13 3.6 0.6737 0.135259835 iYOR105W 0.589656619 0.306799871 0.305027393 "VAM3 -- vacuole biogenesis -- Syntaxin homolog (t-SNARE), required for vacuolar assembly" YPL092W SSU1 1.2 12 3.6 0.6737 0.275282851 iYPL093W 0.537998935 0.32849162 0.625070582 SSU1 -- sulfite tolerance -- Plasma membrane transporter involved in sulfite tolerance YKL119C VPH2 1.1 12 3.6 0.6737 0.813915055 YKLCdelta4 0.56903518 0.915302089 0.289545092 VPH2 -- vacuolar acidification -- Vacuolar H(+)-ATPase (V-ATPase) assembly protein acting in the endoplasmic reticulum YGR081C YGR081C 1 11 3.6 0.6737 0.597636487 iYGR081C 0.21200467 0.719948437 0.345824598 "YGR081C -- unknown -- unknown function, has putative coiled-coil domain" YGR123C PPT1 1 10 3.6 0.6737 0.829827432 iYGR123C itI(AAU)G 0.355032972 0.296151315 0.986809923 0.486679662 0.245894479 "PPT1 -- unknown -- Protein serine/threonine phosphatase of unknown function, member of PPP family of protein phosphatases and related to PP5 phosphatases, has tetratricopeptide (TPR) repeats" YHR169W DBP8 1 10 3.6 0.6737 0.165048267 iYHR168W 0.282508527 0.534477255 0.403039832 DBP8 -- unknown -- similarity to DEAD box family of RNA helicases YLR380W CSR1 1 11 3.6 0.6737 0.192459201 iYLR379W 0.056756974 0.420665765 0.490170802 CSR1 -- unknown -- unknown function YMR003W YMR003W 1 11 3.6 0.6737 0.437370019 iYMR002W 0.61548356 0.473927875 0.631039768 YMR003W -- unknown -- unknown function YNL303W YNL303W 1 10 3.6 0.6737 0.61119267 0.526698209 YNL303W -- unknown -- unknown function YNR054C YNR054C 1 11 3.6 0.6737 0.12480393 iYNR054C-0 iYNR054C-1 0.141845947 0.403746184 0.205130273 0.094795539 0.555904962 "YNR054C -- unknown -- similarity to mouse ABT1, an activator of RNA Polymerase II basal transcription" YLR002C YLR002C 0.9 10 3.6 0.6737 0.597387428 iYLR002C 0.814753175 0.612523657 0.23575419 YLR002C -- unknown -- unknown function YPL144W YPL144W 1.5 16 3.5 0.6654 1 0.933625264 iYPL145C 0.976723293 0.60622506 0.202117888 YPL144W -- unknown -- unknown function YBR067C TIP1 10.7 114 3.5 0.6654 0.629008272 iYBR067C 0.883988064 0.533229556 0.472211019 "TIP1 -- stress response (putative) -- Cold- and heat-shock induced mannocell wall, member of seripauperin (PAU) family" YBR256C RIB5 3.1 33 3.5 0.6654 0.455890019 iYBR256C 0.395114573 0.68132482 0.768616802 "RIB5 -- flavin biosynthesis -- Riboflavin synthase, last step of riboflavin synthesis, converts 6,7-dimethyl-8-ribityllumazine to riboflavin" YOR128C ADE2 3.1 33 3.5 0.6654 0.333289264 iYOR128C 0.379776048 0.629552046 0.510070899 "ADE2 -- purine biosynthesis -- Phosphoribosylaminoimidazole carboxylase (AIR decarboxylase), sixth step in de novo purine biosynthesis pathway" YNL157W YNL157W 3 33 3.5 0.6654 0.536569143 iYNL158W 0.539155472 0.687718379 0.440621979 YNL157W -- unknown -- similarity to Yhr132w-ap and with weak similarity to human ENSA alpha-endosulfine and human ARPP-19 cAMP-regulated phosphoprotein YDL012C YDL012C 2.7 27 3.5 0.6654 0.402848567 iYDL012C 0.349522422 0.451045125 0.3439977 YDL012C -- unknown -- unknown function YER044C YER044C 2.1 22 3.5 0.6654 0.779044786 iYER044C 0.165808823 0.819702602 0.227682888 YER044C -- unknown -- unknown function YGR211W ZPR1 2.1 23 3.5 0.6654 0.583146666 iYGR210C 0.655311446 ZPR1 -- unknown -- Zinc finger unknown function YCL056C YCL056C 2 21 3.5 0.6654 0.038830135 iYCL056C 0.165835203 0.006937162 0.041814373 YCL056C -- unknown -- unknown function YMR054W STV1 1.9 21 3.5 0.6654 0.424176492 iYMR053C 0.263557887 0.701555172 0.259023526 STV1 -- vacuolar acidification -- Subunit of V0 sector of vacuolar ATPase YIL176C YIL176C 1.8 19 3.5 0.6654 0.934822683 0.50660651 YIL176C -- unknown -- Member of seripauperin (PAU) family (PAU1 and YIL176C code for identical proteins) YOR015W YOR015W 1.8 19 3.5 0.6654 0.379728029 0.335866527 YOR015W -- unknown -- unknown function YDL158C YDL158C 1.7 18 3.5 0.6654 0.552735003 0.443676458 YDL158C -- unknown -- unknown function YHR037W PUT2 1.7 18 3.5 0.6654 0.609808893 iYHR036W 0.294595265 0.653039832 0.129097668 "PUT2 -- amino acid biosynthesis -- Delta-1-pyrroline-5-carboxylate dehydrogenase (P5C dehydrogenase), carries out the second step in proline degradationallows proline to be used as a nitrogen source" YBL033C RIB1 1.6 16 3.5 0.6654 0.564231882 iYBL033C 0.714523253 0.497744119 0.602964873 "RIB1 -- flavin biosynthesis -- GTP cyclohydrolase II, initial and rate-limiting step in the riboflavin biosynthesis pathway" YDR051C YDR051C 1.6 17 3.5 0.6654 0.19737292 iYDR051C 0.525037184 0.119714325 0.478071258 YDR051C -- unknown -- unknown function YIL085C KTR7 1.6 16 3.5 0.6654 0.4391817 iYIL085C 0.555840838 0.827214685 0.769738962 KTR7 -- protein glycosylation -- Putative mannosyltransferase of KRE2 family YNL005C MRP7 1.6 17 3.5 0.6654 0.820607228 iYNL005C 0.83130145 0.466896856 0.455977908 MRP7 -- protein synthesis -- Mitochondrial ribosomal large subunit (YmL2) YGR244C LSC2 1.5 16 3.5 0.6654 0.212275681 iYGR244C 0.381207392 0.485237596 0.426393482 LSC2 -- TCA cycle -- Succinyl-CoA ligasebeta subunit of succinyl-CoA synthetase complex which has succinyl-CoA ligase and succinate thiokinase activities YHR098C SFB3 1.5 16 3.5 0.6654 0.741525711 iYHR098C 0.274049424 0.853471668 0.359749916 "SFB3 -- unknown -- transport of plasma membrane ATPase Pma1p from the ER to the Golgi, possible component of COPII vesicles" YHR147C MRPL6 1.5 16 3.5 0.6654 iYHR147C 0.160191031 0.439864483 "MRPL6 -- protein synthesis -- Mitochondrial ribosomal large subunit (YmL16), belongs to L6 family of prokaryotic ribosomal proteins" YLR052W YLR052W 1.5 15 3.5 0.6654 0.203212714 iYLR051C 0.247953254 0.176275332 0.121593291 YLR052W -- unknown -- unknown function YCR060W YCR060W 1.3 14 3.5 0.6654 0.201083971 iYCR059C 0.445807086 0.239606832 0.534553972 "YCR060W -- unknown -- similarity to stress inducible protein Sti1p, has tetratricopeptide (TPR) repeats" YDL200C MGT1 1.3 14 3.5 0.6654 0.320122348 iYDL200C 0.652450876 0.423516827 0.36217079 MGT1 -- DNA repair -- O6-methylguanine DNA repair methyltransferase that carries out a suicide reaction YFR055W YFR055W 1.3 15 3.5 0.6654 0.900773317 0.932482043 YFR055W -- unknown -- similarity to E. coli cystathionine beta-lyase YLR020C YLR020C 1.3 15 3.5 0.6654 0.205922828 iYLR020C 0.316167798 0.371173058 0.184221493 YLR020C -- unknown -- similarity to triacylglycerol lipase YBL032W YBL032W 1.2 13 3.5 0.6654 0.760659082 iYBL033C 0.714523253 0.97571475 0.602964873 "YBL032W -- unknown -- four KH RNA binding motifs, has similarity to mouse hnRNP X protein" YKL114C APN1 1.2 12 3.5 0.6654 0.369137634 iYKL114C 0.480652741 0.652690426 0.416955715 "APN1 -- DNA repair -- AP endonuclease, DNA (apurinic or apyrimidinic site) lyase" YNL199C GCR2 1.2 13 3.5 0.6654 0.222775572 0.45601909 GCR2 -- glycolysis -- Transcriptional activator involved in regulation of glycolytic gene expression YKL112W ABF1 1.1 12 3.5 0.6654 0.234568236 iYKL113C 0.095336791 0.438410269 0.335594573 ABF1 -- transcription -- ARS-binding factor involved in the activation of DNA-replication and transcriptional regulation of various genes YML006C GIS4 1.1 12 3.5 0.6654 0.343957723 iYML006C tS(AGA)M 0.357106052 0.641661297 0.522823262 0.313352827 0.30573631 GIS4 -- unknown -- unknown function YNL107W YAF9 1.1 11 3.5 0.6654 0.440461786 iYNL108C 0.461378084 0.440950384 0.34616967 YAF9 -- unknown -- similarity to human AF-9 protein YOL094C RFC4 1.1 11 3.5 0.6654 0.53131406 iYOL094C 0.548142064 0.794392523 0.174790356 "RFC4 -- DNA replication -- Replication factor C, 37 kDa subunit" YBR104W YMC2 1 11 3.5 0.6654 0.652540044 iYBR103W 0.500672263 0.897636525 0.426561343 YMC2 -- transport -- Member of mitochondrial carrier (MCF) family of membrane transporters YGL257C MNT2 1 11 3.5 0.6654 0.571933337 iYGL257C 0.185512606 0.337662338 0.074541101 MNT2 -- protein glycosylation -- Mannosyltransferase required for addition of terminal mannose residues to O-linked oligosaccharides YGR078C PAC10 1 11 3.5 0.6654 0.139102348 iYGR078C 0.577788571 0.537791401 0.738872645 "PAC10 -- cytoskeleton -- Prefoldin subunit 3, component of Gim protein complex that promotes formation of functional alpha- and gamma-tubulin, and actin" YMR247C YMR247C 1 11 3.5 0.6654 0.320407581 iYMR247C itA(AGC)M2 0.669269026 0.632236905 0.613454868 0.314534322 0.468903767 YMR247C -- unknown -- unknown function YMR274C RCE1 1 11 3.5 0.6654 0.42145329 iYMR274C 0.622739747 0.933712793 0.449947568 RCE1 -- protein processing -- Protease involved in ras and a-factor C-terminal proteolysis YOR119C RIO1 1 11 3.5 0.6654 0.207115717 iYOR119C 0.645225185 0.198667966 0.779396034 RIO1 -- unknown -- similarity to Aspergillus nidulans SUDD suppressor of bimD6 chromosome-spindle attachment defect YOR229W WTM2 1 10 3.5 0.6654 0.220360837 iYOR228C 0.207274703 0.527120649 0.263391755 "WTM2 -- transcription -- Transcriptional modulator meiotic regulation and silencing, member of WD (WD-40) repeat family" YER087W YER087W 0.9 10 3.5 0.6654 0.359681275 iYER086W 0.589187409 0.637896265 0.517896816 YER087W -- unknown -- similarity to E. coli prolyl-tRNA synthetase YJR002W MPP10 0.9 10 3.5 0.6654 0.366059672 iYJR001W 0.354136312 0.482213439 0.235181479 "MPP10 -- rRNA processing -- Component of U3 snoRNP, required for pre-18S rRNA processing" YGR084C MRP13 1.9 21 3.4 0.6561 1 0.849622465 iYGR084C 0.928789504 0.819926779 0.695458552 MRP13 -- protein synthesis -- Mitochondrial ribosomal small subunit YDR041W YDR041W 1.7 18 3.4 0.6561 1 0.842492574 iYDR040C 0.973324248 0.776426039 0.397645601 YDR041W -- protein synthesis -- Putative mitochondrial ribosomal protein YMR099C YMR099C 1.7 18 3.4 0.6561 1 0.909520035 iYMR099C 0.941633151 0.867916999 0.461303284 YMR099C -- unknown -- unknown function YGR182C YGR182C 2.4 26 3.4 0.6561 0.79850828 iYGR182C 0.644273096 0.630050193 0.762228964 YGR182C -- unknown -- unknown function YHR057C CYP2 2.2 25 3.4 0.6561 0.62967088 iYHR057C 0.146339448 0.775346401 0.132935388 "CYP2 -- protein folding -- Cyclophilin (peptidylprolyl cis-trans isomerase or PPIase), ER or secreted isoform, plays a role in the stress response" YNL307C MCK1 2.2 24 3.4 0.6561 0.544229748 iYNL307C 0.270938314 0.709816441 0.167695219 "MCK1 -- meiosis -- Serine/threonine/tyrosine protein kinase, positive regulator of meiosis and spore formation" YBR023C CHS3 2.1 23 3.4 0.6561 0.459156866 iYBR023C 0.32998273 0.731005716 0.774252421 CHS3 -- cell wall biogenesis -- Chitin synthase IIIresponsible for chitin ring at base of bud and chitin in the lateral cell walls and spores YHR146W YHR146W 2 22 3.4 0.6561 0.31984926 iYHRCdelta10 YHRCdelta11 0.434300107 0.676096339 0.660577997 0.478598651 0.679286296 YHR146W -- unknown -- similarity to pheromone adaptation protein Mdg1p YPL170W YPL170W 2 22 3.4 0.6561 0.68081685 iYPL171C 0.844024615 0.169755076 0.453232243 YPL170W -- unknown -- similarity to steroid membrane receptors YBR282W MRPL27 1.9 21 3.4 0.6561 0.601842382 iYBR281C 0.520424245 0.818875893 0.814929358 MRPL27 -- protein synthesis -- Mitochondrial ribosomal large subunit YMR200W ROT1 1.9 21 3.4 0.6561 0.409843921 iYMR199W 0.2063617 0.855181936 0.532378837 ROT1 -- cytoskeleton -- Suppressor of tor2 mutation YPL087W YDC1 1.8 20 3.4 0.6561 0.311615323 iYPL088W 0.39644013 0.457500206 0.526536658 YDC1 -- sphingolipid metabolism -- Alkaline dihydroceramidase YGR220C MRPL9 1.6 17 3.4 0.6561 0.182024844 iYGR220C 0.575815337 0.671110014 0.570151636 MRPL9 -- protein synthesis -- Mitochondrial ribosomal large subunit (YmL9E. coli L3human MRL3) YOR150W MRPL23 1.6 17 3.4 0.6561 0.271350891 iYOR149C 0.246080875 0.865465317 0.75337952 MRPL23 -- protein synthesis -- Mitochondrial ribosomal large subunit YPR094W YPR094W 1.6 17 3.4 0.6561 0.539744212 iYPR093C 0.517750232 0.459226771 YPR094W -- unknown -- unknown function YKL207W YKL207W 1.5 16 3.4 0.6561 0.436423198 iYKL208W 0.338663732 0.698723065 0.233186887 YKL207W -- unknown -- unknown function YMR150C IMP1 1.5 16 3.4 0.6561 0.26805243 0.611438251 "IMP1 -- protein processing -- Catalytic subunit of mitochondrial inner membrane protease Imp, responsible for removal of signal peptides from some proteins of intermembrane space" YNL003C PET8 1.5 16 3.4 0.6561 0.631879028 iYNL003C 0.777041948 0.552149714 0.346654275 "PET8 -- mitochondrial protein targeting -- mitochondrial carrier (MCF) family, has similarity to Mrs4p and Mrs3p" YPL059W GRX5 1.5 17 3.4 0.6561 0.380329858 YPLCTy4-1E iYPLCtau2 0.386551815 0.36415616 0.6896249 0.582560297 0.530212697 "GRX5 -- oxidative stres response -- Glutaredoxin, involved in protection against protein oxidative damage" YPL149W APG5 1.5 16 3.4 0.6561 0.605162397 iYPL150W 0.327920251 0.941840768 0.728598882 APG5 -- autophagy -- autophagy and nutrient starvation YBR002C RER2 1.3 15 3.4 0.6561 0.585775757 iYBR002C 0.67035393 0.839360587 0.838531514 "RER2 -- protein glycosylation -- Cis-prenyltransferase, involved in dolichol synthesis" YER026C CHO1 1.3 14 3.4 0.6561 0.597134252 iYER026C 0.433738848 0.774212129 0.610631604 "CHO1 -- phospholipid metabolism -- Phosphatidylserine synthase, CDP-diacylglycerol serine O-phosphatidyltransferase" YGR257C YGR257C 1.3 15 3.4 0.6561 0.792514458 iYGR257C 0.34824562 0.80214425 0.179419986 YGR257C -- unknown -- Member of mitochondrial carrier family (MCF) of membrane transporters YIL048W NEO1 1.3 15 3.4 0.6561 0.437625039 iYIL049W 0.293886953 0.797439224 0.411224821 NEO1 -- neomycin resistance -- ATPase that leads to neomycin-resistant protein when overexpressed YMR319C FET4 1.3 15 3.4 0.6561 0.34014874 iYMR319C-0 iYMR319C-1 0.574810016 0.490153549 0.234345429 0.732033516 0.34094174 FET4 -- transport -- Low-affinity Fe(II) transport protein YGR101W YGR101W 1.2 14 3.4 0.6561 0.2777173 iYGR100W 0.365731254 0.323261858 0.32717593 "YGR101W -- unknown -- unknown function, possibly involved in respiration" YPR114W YPR114W 1.2 13 3.4 0.6561 0.2898461 iYPR113W 0.146592197 0.32659204 0.046820405 YPR114W -- unknown -- unknown function YBR265W TSC10 1.1 12 3.4 0.6561 0.186259505 iYBR264C 0.458036438 0.774754985 0.58869572 "TSC10 -- sphingolipid biosynthesis -- 3-Ketosphinganine reductase, catalyzes the second step in the synthesis of phytosphingosine" YNR012W URK1 1.1 12 3.4 0.6561 0.310671983 iYNR011C 0.2283917 0.610774142 0.426275332 "URK1 -- pyrimidine metabolism -- Uridine kinase, converts ATP and uridine to ADP and UMP" YOR291W YOR291W 1.1 11 3.4 0.6561 0.443018765 iYOR290C 0.555173707 0.190951917 0.17168954 YOR291W -- unknown -- Member of cation translocating P-type ATPase superfamily YBL018C POP8 1 11 3.4 0.6561 0.819931683 iYBL018C 0.223106276 0.935406895 0.365835596 "POP8 -- tRNA processing -- Subunit of both RNase P and RNase MRP, which are needed for tRNA processing and 5.8S rRNA processing, respectively" YFL001W DEG1 1 11 3.4 0.6561 0.514762874 iYFL002C 0.488667638 0.493535515 0.292292849 DEG1 -- tRNA processing -- Pseudouridine synthase that catalyzes the formation of pseudouridine-38 and -39 in cytoplasmic and mitochondrial tRNAs YFR028C CDC14 1 11 3.4 0.6561 0.608599184 iYFR028C itY(GUA)F2 0.489935441 0.769258233 0.85948668 0.197124756 0.475786735 CDC14 -- mitosis -- Dual specificity protein phosphatase (PTPase) that performs a function late in the cell cycle YJR118C ILM1 1 11 3.4 0.6561 0.755511305 iYJR118C 0.583569294 0.723171125 0.545520464 "ILM1 -- mitochondrial genome maintenance (putative) -- unknown function, possibly involved in mitochondrial DNA maintenance" YKL166C TPK3 1 11 3.4 0.6561 0.436232943 iYKL166C-0 iYKL166C-1 0.245007635 0.408771643 0.609732517 0.103351955 0.679438574 "TPK3 -- signaling, nutrient control of cell growth -- cAMP-dependent protein kinase 3 or protein kinase A (PKA) catalytic subunit" YMR102C YMR102C 1 12 3.4 0.6561 0.51018225 iYMR102C 0.342820103 0.537872066 0.215275431 "YMR102C -- unknown -- unknown function, contains WD (WD-40) repeats" YNL038W YNL038W 1 11 3.4 0.6561 0.145620852 iYNL039W 0.224503197 0.594795539 0.064644852 YNL038W -- unknown -- unknown function YNL188W KAR1 1 10 3.4 0.6561 0.152403769 iYNL189W 0.681908628 0.15075818 0.784382768 KAR1 -- cytoskeleton -- spindle pole body duplication and karyogamy YNL292W PUS4 1 11 3.4 0.6561 0.23693896 iYNL293W 0.592189657 0.363213924 0.110055866 PUS4 -- tRNA processing -- Pseudouridine synthase that creates pseudouridine-55 in cytoplasmic and mitochondrial tRNAs YNR038W DBP6 1 11 3.4 0.6561 0.593375673 iYNR037C 0.065828161 0.52434158 0.341961143 DBP6 -- rRNA processing -- Putative RNA helicase required for ribosomal RNA processing and biogenesis of 60S ribosomal subunit YCR097W A1 0.9 10 3.4 0.6561 0.991608915 iYCR096C YCR097W-A 0.988131424 0.971347271 0.647326417 0.256664006 0.57442348 "A1 -- transcription -- Homeodomain regulatory proteinwith Alpha2p, represses transcription of haploid-specific genes in diploid cells" YIL079C YIL079C 0.9 10 3.4 0.6561 0.551744012 iYIL079C 0.26756644 0.723445143 0.51908707 YIL079C -- unknown -- similarity to gag polyprotein YKL225W YKL225W 0.9 10 3.4 0.6561 0.995812371 0.112955205 YKL225W -- unknown -- unknown function YLR409C YLR409C 0.9 9 3.4 0.6561 0.505255619 iYLR409C 0.672771617 0.56632083 0.545136284 "YLR409C -- unknown -- unknown function, has WD (WD-40) repeats" YPR120C CLB5 0.9 9 3.4 0.6561 0.296645941 itC(GCA)P2 iYPR120C 0.362774997 0.269847765 0.282014682 0.333145116 0.435427926 "CLB5 -- cell cycle -- B-type cyclin appearing late in G1, involved in initiation of DNA synthesis" YPR146C YPR146C 0.9 10 3.4 0.6561 0.482425911 0.605426975 YPR146C -- unknown -- unknown function YEL055C POL5 0.8 9 3.4 0.6561 0.764265906 iYEL055C 0.893724121 0.470109571 0.822033482 POL5 -- DNA replication -- DNA polymerase V that has motifs typical of DNA polymerase family YKL175W YKL175W 1.8 20 3.3 0.6458 1 0.939155006 iYKL176C 0.983139099 0.708414555 0.093216281 YKL175W -- unknown -- Vacuolar membrane the regulation of zinc storage YHR001W-A QCR10 2.6 28 3.3 0.6458 0.595473705 iYHR001W 0.343448015 0.519916143 0.26232206 QCR10 -- oxidative phosphorylation -- Ubiquinol cytochrome-c reductase subunit (8.5 kDa protein)component of ubiquinol cytochrome-c reductase complex YOR326W MYO2 2.4 27 3.3 0.6458 0.315505029 iYOR325W 0.557269444 0.364163713 0.536896723 "MYO2 -- cytoskeleton -- Myosin heavy chain, class V, involved in polarized growth and secretion" YKL104C GFA1 2.2 26 3.3 0.6458 0.642703685 iYKL104C 0.380582958 0.942401053 0.398996133 "GFA1 -- cell wall biogenesis -- Glucosamine--fructose-6-phosphate aminotransferase, isomerizing (hexosephosphate aminotransferase), first step in chitin biosynthesis pathway" YDL053C YDL053C 2 23 3.3 0.6458 0.277634808 iYDL053C 0.577538435 0.215104462 0.517706303 YDL053C -- unknown -- Protein possibly involved in proteasome function YGR167W CLC1 2 23 3.3 0.6458 0.552137876 iYGR166W 0.521604969 0.468076616 0.291844801 "CLC1 -- endocytosis and secretion -- Clathrin light chain, involved in the internalization step of endocytosis" YBR210W YBR210W 1.9 21 3.3 0.6458 0.709517353 iYBR209W itC(GCA)B 0.756498061 0.190865028 0.785027952 0.233019852 0.161879013 "YBR210W -- unknown -- unknown function, has similarity to Erv14p, a ER-derived vesicles" YCL054W SPB1 1.8 20 3.3 0.6458 0.335383918 iYCL055W-0 iYCL055W-1 0.563733949 0.711333167 0.395234877 0.473904977 0.701901386 SPB1 -- ribosome biogenesis -- Putative S-adenosyl-methionine-dependent methyltransferase required for synthesis of 60S ribosomal subunit YOR215C YOR215C 1.8 20 3.3 0.6458 0.376499778 iYOR215C 0.097857322 0.315178859 0.063003545 YOR215C -- unknown -- unknown function YML007W YAP1 1.7 18 3.3 0.6458 0.570859697 iYML008C 0.303277182 0.498911027 0.365203512 "YAP1 -- oxidative stress -- Transcriptional activator of basic leucine zipper (bZIP) family, involved in oxidative stress response" YDL047W SIT4 1.6 17 3.3 0.6458 0.199265594 iYDL048C-0 iYDL048C-1 0.424348861 0.342138379 0.412524366 0.354509178 0.255474624 "SIT4 -- cell cycle -- Protein serine/threonine phosphatase involved in cell cycle regulation, member of PPP family of protein phosphatases and related to PP2A phosphatase" YER100W UBC6 1.6 17 3.3 0.6458 0.406316035 iYER099C 0.428307329 0.576510721 0.632472385 "UBC6 -- protein degradation, ubiquitin-mediated -- Ubiquitin-conjugating enzymeanchored in the ER membrane with the catalytically active domain in cytoplasm" YER155C BEM2 1.6 17 3.3 0.6458 0.453300025 iYER155C 0.24485866 0.522665603 0.129268493 BEM2 -- bud emergence -- GTPase-activating (GAP) regulates Rho1p and has a role in bud emergence and cell cycle-related cytoskeletal reorganization YLR066W SPC3 1.6 18 3.3 0.6458 0.419373459 iYLR065C 0.48670498 0.49792498 0.557748172 SPC3 -- secretion -- Subunit of signal peptidase complex YPR020W ATP20 1.6 18 3.3 0.6458 0.506082736 iYPR019W 0.605156582 0.532274417 0.558488394 ATP20 -- ATP synthesis -- F1F0-ATP synthase complex F0 membrane domain g subunit Q0080 1.5 17 3.3 0.6458 YDL103C QRI1 1.5 16 3.3 0.6458 0.654745171 iYDL103C 0.177942149 0.776803119 0.120674357 QRI1 -- UDP-N-acetylglucosamine biosynthesis -- UDP-N-acetylglucosamine pyrophosphorylase YDR237W MRPL7 1.5 16 3.3 0.6458 0.186038321 iYDR236C 0.133376406 0.375380196 0.478202095 "MRPL7 -- protein synthesis -- Mitochondrial ribosomal large subunit (YmL5/YmL7), belongs to the L5 family of prokaryotic ribosomal proteins" YIL033C SRA1 1.5 17 3.3 0.6458 0.65990046 iYIL033C 0.320470148 0.717436024 0.179806006 SRA1 -- signaling? -- Regulatory subunit of cAMP-dependent protein kinases YIR004W DJP1 1.5 16 3.3 0.6458 0.495270671 iYIR003W 0.691848276 0.632733726 0.287947148 DJP1 -- peroxisome biogenesis -- peroxisomal biogenesishas similarity to E. coli DnaJ and other DnaJ-like proteins YOL027C YOL027C 1.5 16 3.3 0.6458 0.276454357 iYOL027C 0.664990715 0.51077519 0.75591416 YOL027C -- unknown -- unknown function YOR196C LIP5 1.5 17 3.3 0.6458 0.072947001 iYOR196C 0.226320001 0.109102027 0.184728051 "LIP5 -- fatty acid metabolism -- Lipoic acid synthase, mutants cannot synthesize lipoic acid, but can attach lipoic acid to protein" YPL024W NCE4 1.5 16 3.3 0.6458 0.191194483 iYPL025C 0.122477117 0.133902675 0.241720176 NCE4 -- cell separation -- Negative regulator of CTS1 expression YAL021C CCR4 1.3 15 3.3 0.6458 0.429605242 iYAL021C 0.482393486 0.63534978 0.276357183 CCR4 -- catabolite repression -- Component of CCR4 transcriptional complexhas positive and negative effects on transcription YBL005W-A 1.3 16 3.3 0.6458 0.349465391 iYBL005W YBLWdelta8 0.725733875 0.604635622 0.475498479 0.492717847 0.541666667 YCL055W KAR4 1.3 16 3.3 0.6458 0.490720706 iYCL056C 0.165835203 0.631284916 0.041814373 KAR4 -- karyogamy -- Regulatory pheromone induction of karyogamy genes YKR084C HBS1 1.3 15 3.3 0.6458 0.303021524 iYKR084C 0.512543639 0.814787199 0.612486892 HBS1 -- unknown -- Protein related to translation elongation factor EF-1alpha and to Sup35p YLR195C NMT1 1.3 16 3.3 0.6458 0.608971782 iYLR195C 0.432717076 0.852052991 0.36054256 "NMT1 -- protein processing -- N-myristoyltransferase, catalyzes cotranslational transfer of myristate from myristoyl-CoA to N-terminal glycine of certain nascent proteins" YPR009W YPR009W 1.3 15 3.3 0.6458 0.438323695 iYPR008W 0.909180638 0.635916855 0.577218728 YPR009W -- unknown -- unknown function YGR246C BRF1 1.2 14 3.3 0.6458 0.317067288 iYGR246C 0.49060464 0.677905945 0.633200319 "BRF1 -- transcription -- Component of RNA polymerase III transcription initiation factor B, 70K subunit" YNL168C YNL168C 1.2 14 3.3 0.6458 0.873082684 iYNL168C 0.535723464 0.981308411 0.545777204 YNL168C -- unknown -- similarity to E. coli hpcE gene product which is involved in degradation of aromatic compounds YOR094W ARF3 1.2 14 3.3 0.6458 0.448586322 iYOR093C 0.589891508 0.365671028 0.610587002 ARF3 -- secretion -- similarity to members of arf family (ras superfamily) of GTP-binding proteins YPR169W YPR169W 1.2 14 3.3 0.6458 0.118172556 iYPR168W 0.661323197 0.135594586 0.459385335 YPR169W -- unknown -- unknown function YBR075W YBR075W 1.1 13 3.3 0.6458 0.708510291 iYBR074W 0.479535711 0.890103751 0.461372706 YBR075W -- unknown -- unknown function YDL155W CLB3 1.1 12 3.3 0.6458 0.319269132 iYDL156W 0.646326159 0.725911298 0.70689167 CLB3 -- cell cycle -- G2/M-phase-specific cyclin YDR038C ENA5 1.1 13 3.3 0.6458 0.536377522 iYDR038C 0.482591419 0.354385045 0.878094775 ENA5 -- transport -- P-type ATPase involved in Na+ efflux YFL066C YFL066C 1.1 13 3.3 0.6458 0.940779629 iYFL066C 0.924448497 0.635569532 0.686671987 "YFL066C -- unknown -- near identity to other subtelomerically-encoded proteins including Yil177p, Yhl050p, and Yer190p" YGL210W YPT32 1.1 13 3.3 0.6458 0.514879433 iYGL211W 0.308748998 0.839181287 0.452151732 "YPT32 -- secretion -- GTP-binding protein required in the secretory pathway at the stage of formation of trans-Golgi vesicles, member of rab family in the ras superfamily" YJL115W ASF1 1.1 13 3.3 0.6458 0.047138333 iYJL116C 0.215122068 0.08952522 0.303460515 "ASF1 -- transcription -- Component of replication-coupling assembly factor (RCAF), anti-silencing causes derepression of silent loci when overexpressed" YJR054W YJR054W 1.1 13 3.3 0.6458 0.610976323 iYJR053W 0.293123062 0.91790203 0.367508268 YJR054W -- unknown -- unknown function YMR148W YMR148W 1.1 12 3.3 0.6458 0.456664369 iYMR147W 0.474626619 0.587529571 0.62191358 YMR148W -- unknown -- unknown function YNL078W YNL078W 1.1 12 3.3 0.6458 0.535029576 iYNL079C 0.082929148 0.669996777 0.01161775 YNL078W -- unknown -- unknown function YPR144C YPR144C 1.1 12 3.3 0.6458 0.392852533 iYPR144C SNR45 0.585774404 0.811626906 0.55795757 0.51931919 0.455607669 "YPR144C -- unknown -- unknown function, has strong similarity to an S. pombe unknown function" YBR061C YBR061C 1 11 3.3 0.6458 0.786718926 iYBR061C 0.781543146 0.924336533 0.817392592 YBR061C -- unknown -- similarity to Ctr86p and E. coli ftsJ YJL063C MRPL8 1 12 3.3 0.6458 0.332332589 iYJL063C 0.263715131 0.735209413 0.52365671 MRPL8 -- protein synthesis -- Mitochondrial ribosomal large subunit (YmL8) YKL137W YKL137W 1 12 3.3 0.6458 0.432877197 iYKL138C 0.06210777 0.454384125 0.064937158 "YKL137W -- unknown -- respiratory growth, for normal distribution of actin patches, and for normal resistance to NaCl and H2O2" YLR426W YLR426W 1 11 3.3 0.6458 0.302671105 iYLR425W 0.204183534 0.711068891 0.058174936 "YLR426W -- unknown -- similarity to Fox2p, E. coli 3-oxoacyl-[acyl-carrier protein] reductase and insect-type alcohol dehydrogenase/ribitol dehydrogenase family" YMR304C-A 1 12 3.3 0.6458 0.689441588 0.536549708 YNL323W YNL323W 1 11 3.3 0.6458 0.626143903 iYNL324W 0.143486928 0.634904962 0.141340782 YNL323W -- unknown -- similarity to Ycx1p YPL101W YPL101W 1 11 3.3 0.6458 0.074580862 0.361619747 YPL101W -- unknown -- unknown function YKL069W YKL069W 0.9 11 3.3 0.6458 0.335254544 iYKL070W 0.521290617 0.856590396 0.837638077 YKL069W -- unknown -- unknown function YOR006C YOR006C 0.9 9 3.3 0.6458 0.103434571 iYOR006C 0.071151987 0.13059942 0.050769357 YOR006C -- unknown -- unknown function YLR401C YLR401C 1 12 3.2 0.6377 1 0.98731847 iYLR401C 0.984731152 0.648284118 0.352665968 YLR401C -- unknown -- weak similarity to R. capsulatus protein nifR3 YBR036C CSG2 2.7 31 3.2 0.6377 0.47604725 iYBR036C 0.089220444 0.625219473 0.243494424 CSG2 -- sphingolipid metabolism -- synthesis of mannosylated sphingolipids YDR214W YDR214W 2.4 27 3.2 0.6377 0.226348619 iYDR213W 0.614462705 0.791380686 0.547313282 YDR214W -- unknown -- unknown function YER023W PRO3 2.1 25 3.2 0.6377 0.450788515 iYER022W 0.141739411 0.657286267 0.050899411 PRO3 -- proline biosynthesis -- Delta-1-pyrroline-5-carboxylate reductase (P5C reductase)carries out last (third) step in proline biosynthesis pathway YDR152W YDR152W 1.9 23 3.2 0.6377 iYDR151C 0.48923339 0.750725105 YDR152W -- unknown -- unknown function YOL026C YOL026C 1.9 23 3.2 0.6377 0.698689605 iYOL026C itS(GCU)O 0.389840928 0.640086515 0.766599794 0.139469226 0.305913632 YOL026C -- unknown -- unknown function YAL053W YAL053W 1.8 20 3.2 0.6377 0.856395216 iYAL054C 0.675166795 0.612244898 0.594972067 YAL053W -- unknown -- unknown function YDR264C AKR1 1.8 21 3.2 0.6377 0.837196442 iYDR264C 0.806919898 0.860377054 0.655494683 "AKR1 -- signaling, pheromone pathway; endocytosis; cell shape control -- Ankyrin repeat-containing proteinhas an inhibitory effect on signaling in the pheromone pathway" YIR011C STS1 1.8 20 3.2 0.6377 0.318632175 iYIR011C 0.134793521 0.33033342 0.142615749 STS1 -- nuclear protein targeting -- when overexpressed restores protein transport and rRNA stability to a sec23 mutation YLL048C YBT1 1.8 21 3.2 0.6377 0.470746792 iYLL048C 0.633126429 0.57554247 0.293680297 "YBT1 -- transport -- similarity to mammalian ATP-dependent bile acid transporter, member of ATP-binding cassette (ABC) superfamily" YER112W LSM4 1.7 20 3.2 0.6377 0.284809853 iYER111C 0.415947846 0.595760234 0.683123509 LSM4 -- mRNA splicing -- U6 snRNA-associated Sm-like group YJR073C OPI3 1.7 20 3.2 0.6377 0.788358118 iYJR073C 0.719523941 0.753544956 0.45754717 "OPI3 -- phospholipid metabolism -- Phospholipid-N-methyltransferase, carries out the second and third methylation steps of phosphatidylcholine biosynthesis pathway" YML070W DAK1 1.7 20 3.2 0.6377 0.298732353 iYML071C tR(UCU)M2 0.894407765 0.563308948 0.540328099 0.848108413 0.225481142 DAK1 -- carbohydrate metabolism; stress response -- Putative dihydroxyacetone kinase YBR049C REB1 1.6 18 3.2 0.6377 0.576572101 iYBR049C 0.13271282 0.692997614 0.171562577 REB1 -- transcription -- Termination factor for RNA polymerase I and transcription factor for RNA polymerase II YDR284C DPP1 1.6 18 3.2 0.6377 0.260482543 iYDR284C 0.338133078 0.792136642 0.629967909 DPP1 -- phospholipid metabolism -- Diacylglycerol pyrophosphate phosphatase YIL030C SSM4 1.6 18 3.2 0.6377 0.508965783 iYIL030C itK(CUU)I 0.685529198 0.667625933 0.790742219 0.596654275 0.70865822 "SSM4 -- mRNA decay -- mRNA turnover, inactivation suppresses mRNA instability due to rna14-3 mutation" YIL145C YIL145C 1.6 18 3.2 0.6377 0.430367737 iYIL145C 0.320632837 0.860427188 0.357704403 YIL145C -- unknown -- similarity to E. coli pantoate beta-alanine ligase (pantothenate synthetase) YLR203C MSS51 1.6 18 3.2 0.6377 0.528689745 iYLR203C 0.403671151 0.892715094 0.382066277 "MSS51 -- mRNA splicing, COX1 and COB mRNA -- respiratory growthpossibly involved in translational activation of mitochondrial COX1 mRNA" YMR047C NUP116 1.6 18 3.2 0.6377 0.27657388 iYMR047C 0.168601696 0.327693536 0.105750487 NUP116 -- nuclear protein targeting -- Nuclear pore protein (nucleoporin) of GLFG familymay be involved in binding and translocation of nuclear proteins YNL313C YNL313C 1.5 17 3.2 0.6377 0.339210313 iYNL313C 0.397146539 0.541928721 0.448505523 "YNL313C -- unknown -- unknown function, has tetratricopeptide (TPR) repeats" YOR061W CKA2 1.5 17 3.2 0.6377 0.542542139 iYOR060C 0.39952033 0.630111524 0.227438112 "CKA2 -- cell cycle -- Casein kinase II (Protein kinase CK2), catalytic (alpha-prime) subunit" YOR085W OST3 1.5 17 3.2 0.6377 0.254167395 iYOR084W 0.583376768 0.526659676 0.41168004 OST3 -- protein glycosylation -- Oligosaccharyltransferase gamma subunitmember of a complex of 8 ER proteins that transfers core oligosaccharide from dolichol carrier to Asn-X-Ser/Thr motif YPL118W MRP51 1.5 17 3.2 0.6377 0.410060724 iYPL119C 0.250373451 0.513433592 0.148276146 MRP51 -- protein synthesis -- Mitochondrial ribosomal small subunit YGR281W YOR1 1.3 15 3.2 0.6377 0.403205573 iYGR280C 0.357014334 0.336338532 0.262465817 "YOR1 -- transport -- Oligomycin-resistance factor, member of ATP-binding cassette (ABC) superfamily" YHR039C YHR039C 1.3 15 3.2 0.6377 0.544863482 iYHR039C 0.74155482 0.453980802 0.287589753 YHR039C -- unknown -- strong similarity to aldehyde dehydrogenases YLR005W SSL1 1.3 16 3.2 0.6377 0.706285422 iYLR004C 0.857989891 0.558966862 0.334814449 SSL1 -- transcription -- Component of RNA polymerase II transcription initiation factor TFIIH YMR005W MPT1 1.3 16 3.2 0.6377 0.384014532 iYMR004W 0.120025726 0.225299282 0.161076171 MPT1 -- protein synthesis -- Component of RNA polymerase II general transcription factor TFIID YNR039C ZRG17 1.3 16 3.2 0.6377 0.332259131 iYNR039C 0.140885804 0.546332551 0.374450015 ZRG17 -- unknown -- weak similarity to Anopheles mitochondrial NADH dehydrogenase subunit 2 YBR220C YBR220C 1.2 14 3.2 0.6377 0.624156651 iYBR220C 0.243764408 0.929503706 0.41245012 "YBR220C -- unknown -- similarity to human acetyl coenzyme A transporter, E. coli ampG protein, and other acetyl-CoA transporter proteins" YBR291C CTP1 1.2 14 3.2 0.6377 0.229924086 iYBR291C 0.569666776 0.287869114 0.50459233 "CTP1 -- transport -- Mitochondrial inner membrane citrate transport protein, member of mitochondrial carrier family (MCF) protein family" YIL020C HIS6 1.2 14 3.2 0.6377 0.741041441 iYIL020C 0.853729617 0.416440543 0.259336936 HIS6 -- histidine biosynthesis -- Phosphoribosyl imidazolecarboxamide isomerase YLR220W CCC1 1.2 15 3.2 0.6377 0.096607963 iYLR219W 0.270366278 0.223942538 0.005800838 "CCC1 -- ion homeostasis, Ca2+ and Mn2+ -- potential role in calcium regulation, overproduction suppresses the calcium-sensitive phenotype of csg1 strains" YMR195W YMR195W 1.2 14 3.2 0.6377 0.442204954 YMR194C-A iYMR194C-A 0.13518241 0.217459418 0.689252336 0.082291315 0.299353599 YMR195W -- unknown -- unknown function YBR125C PTC4 1.1 14 3.2 0.6377 0.181718758 iYBR125C 0.429169499 0.747099581 0.212700908 PTC4 -- unknown -- Serine/threonine protein phosphatase of PP2C family YBR166C TYR1 1.1 14 3.2 0.6377 0.66208712 iYBR166C 0.559263946 0.839235299 0.55510796 "TYR1 -- tyrosine biosynthesis -- Prephenate dehydrogenase (NADP+), step of tyrosine biosynthesis pathway" YLR049C YLR049C 1.1 13 3.2 0.6377 0.719291081 iYLR049C 0.151100512 0.820945177 0.160611693 YLR049C -- unknown -- unknown function YMR125W STO1 1.1 12 3.2 0.6377 0.693903769 iYMR124W 0.182637718 0.833595388 0.199463221 STO1 -- glycolysis -- Large subunit of nuclear cap-binding protein complex YPR119W CLB2 1.1 13 3.2 0.6377 0.454572945 iYPR118W tK(UUU)P 0.612566796 0.780386895 0.289719626 0.417422602 0.800516254 CLB2 -- cell cycle -- G2/M-phase-specific cyclin YMR289W YMR289W 1 12 3.2 0.6377 0.139096353 iYMR288W 0.104766118 0.505677848 0.041201434 YMR289W -- unknown -- unknown function YOR240W YOR240W 1 12 3.2 0.6377 0.020510456 0.092592593 YOR240W -- unknown -- Putative methyltransferase unknown role YFR018C YFR018C 0.8 9 3.2 0.6377 0.817228291 iYFR018C 0.333740209 0.790928134 0.110136452 YFR018C -- unknown -- similarity to human glutaminyl-peptide cyclotransferase YOL059W GPD2 1.2 14 3.1 0.6294 1 0.882457431 iYOL060C 0.995398953 0.773716699 0.633863031 GPD2 -- glycerol metabolism -- Glycerol-3-phosphate dehydrogenase (NAD+)involved in glycerol production converting glycerol-3-phosphate and NAD+ to dihydroxyacetone phosphate and NADH YLR403W SFP1 1.1 13 3.1 0.6294 1 0.812303583 iYLR402W 0.970000438 0.84660814 0.538356054 "SFP1 -- unknown -- Zinc finger nuclear protein localization, three dispersed C2H2-type zinc fingers" YBR207W FTH1 2.8 34 3.1 0.6294 0.319292194 iYBR206W 0.342173553 0.401149037 0.569649378 FTH1 -- unknown -- Vacuolar iron transporter with similarity to Ftr1p YCL031C RRP7 2.5 29 3.1 0.6294 0.550176809 iYCL031C 0.129203827 0.4194282 0.067251462 RRP7 -- rRNA processing -- pre-rRNA processing and ribosome assembly YGL191W COX13 2.2 27 3.1 0.6294 0.799121052 iYGL192W 0.250496199 0.977924589 0.3778826 COX13 -- oxidative phosphorylation -- Cytochrome-c oxidase chain VIa YIL035C CKA1 2.2 27 3.1 0.6294 0.747705374 iYIL035C 0.125173024 0.833439745 0.159281341 "CKA1 -- cell cycle (putative) -- Casein kinase II (protein kinase CK2), catalytic (alpha) subunit" YDR434W YDR434W 2.1 25 3.1 0.6294 0.792069437 iYDR433W 0.647702365 0.945601249 0.400660651 YDR434W -- unknown -- unknown function YKL212W SAC1 1.9 22 3.1 0.6294 0.647162379 iYKL213C 0.108148529 0.929824561 0.108799185 "SAC1 -- secretion -- Polyphosphoinositide phosphatase, required for transport of ATP into ER which plays a role in Golgi function and actin cytoskeletal organization" YBL056W PTC3 1.8 22 3.1 0.6294 0.414793762 iYBL057C 0.69810621 0.793615984 0.941739824 PTC3 -- osmotic stress response (putative) -- Protein serine/threonine phosphatase of PP2C family YHR142W CHS7 1.7 21 3.1 0.6294 0.963763406 iYHR141C 0.601883986 0.781708595 0.063426911 CHS7 -- cell wall biogenesis -- the regulated transport of chitin synthase III (Chs3p) from the ER YLR262C YPT6 1.7 20 3.1 0.6294 0.29627173 iYLR262C YLR262C-A 0.394842432 0.057400113 0.436844864 0.435365753 0.002739285 "YPT6 -- secretion -- GTP-binding the secretory pathway, member of rab family in the ras superfamily" YDR335W MSN5 1.6 18 3.1 0.6294 0.326035444 iYDR334W 0.102718224 0.657497782 0.323476914 MSN5 -- signaling -- Importin-beta family member required for nuclear export of Pho4p and involved in pheromone response pathway YKL003C MRP17 1.6 19 3.1 0.6294 0.571608377 iYKL003C 0.164667547 0.728079374 0.248630358 MRP17 -- protein synthesis -- Mitochondrial ribosomal small subunit YOR241W MET7 1.6 19 3.1 0.6294 0.307614308 iYOR240W 0.641033346 0.679337232 0.763190077 "MET7 -- unknown -- Folylpolyglutamate synthetase, involved in methionine biosynthesis and maintenance of mitochondrial genome" YGR077C PEX8 1.5 18 3.1 0.6294 0.309797233 iYGR077C 0.531068433 0.632774284 0.333305171 PEX8 -- peroxisome biogenesis -- Peroxisomal protein (peroxin) involved in protein import into peroxisomes YNL284C MRPL10 1.5 17 3.1 0.6294 0.525381453 iYNL284C itT(AGU)N1 0.694099437 0.605169449 0.900056465 0.779301444 0.544145478 "MRPL10 -- protein synthesis -- Mitochondrial ribosomal large subunit (YmL10), member of L15 family of prokaryotic ribosomal proteins" YML010W SPT5 1.3 16 3.1 0.6294 0.389168502 iYML011C 0.277242432 0.591408632 0.166666667 SPT5 -- transcription -- chromatin structure that influences expression of many genes YMR080C NAM7 1.3 16 3.1 0.6294 0.438581489 iYMR080C 0.410139048 0.861608652 0.164832285 NAM7 -- mRNA decay -- involved with Nmd2p and Upf3p in decay of mRNA containing nonsense codons YIL074C SER33 1.2 14 3.1 0.6294 0.367654201 iYIL074C 0.522404123 0.812051077 0.516771488 SER33 -- serine biosynthesis -- 3-phosphoglycerate dehydrogenaseinvolved in synthesis of serine from 3-phosphoglycerate YLR089C YLR089C 1.2 15 3.1 0.6294 0.302605884 iYLR089C 0.026699819 0.833901884 0.14679503 YLR089C -- unknown -- Putative mitochondrial alanine aminotransferase YNL155W YNL155W 1.2 14 3.1 0.6294 0.775142263 iYNL156C 0.493966305 0.888253303 0.59587496 YNL155W -- unknown -- unknown function YNR020C YNR020C 1.2 15 3.1 0.6294 0.049333458 iYNR020C 0.489209578 0.310022559 0.41106818 YNR020C -- unknown -- unknown function YOR315W YOR315W 1.2 15 3.1 0.6294 0.510690511 iYOR314W 0.537594056 0.44217024 0.733645237 YOR315W -- unknown -- unknown function YPL274W SAM3 1.2 14 3.1 0.6294 0.088994292 iYPL275W-0 iYPL275W-1 0.668815738 0.521744806 0.172056282 0.510831586 0.709865877 "SAM3 -- transport, amino acid -- High affinity S-adenosylmethionine permease, has similarity to Gap1p and other amino acid permeases" YER016W BIM1 1.1 14 3.1 0.6294 0.42435528 iYER015W 0.453159412 0.373774924 0.68443735 "BIM1 -- cytoskeleton -- associated with microtubules, required for a cell cycle check point" YGL114W YGL114W 1.1 14 3.1 0.6294 0.623393289 iYGL115W 0.826048243 0.656864325 0.45004834 YGL114W -- unknown -- member of oligopeptide transporter (OPT) family of membrane transporters YMR300C ADE4 1.1 13 3.1 0.6294 0.681442416 iYMR300C 0.620148935 0.979017527 0.768670209 ADE4 -- purine biosynthesis -- Amidophosphoribosyltransferase (glutamine phosphoribosylpyrophosphate amidotransferase)catalyzes the first step in de novo purine biosynthesis YOR217W RFC1 1.1 14 3.1 0.6294 0.195547289 iYOR216C 0.451985529 0.203914861 0.088489151 RFC1 -- DNA replication -- DNA replication protein RFC large subunit YBL016W FUS3 1 12 3.1 0.6294 0.733702996 iYBL017C 0.413701706 0.925878182 0.443735036 FUS3 -- mating (cell cycle arrest) -- Serine/threonine protein kinase required for cell cycle arrest and for cell fusion during matingmember of MAP kinase family YDR248C YDR248C 1 12 3.1 0.6294 0.310607886 iYDR248C 0.261884708 0.241420591 0.463163231 YDR248C -- unknown -- similarity to E. coli gluconate kinase gntV YGR152C RSR1 1 12 3.1 0.6294 0.480886361 iYGR152C 0.083265828 0.533193515 0.1424703 "RSR1 -- bud site selection -- GTP-binding bud site selection, member of ras family in the ras superfamily" YKL205W LOS1 1 13 3.1 0.6294 0.315654356 iYKL206C 0.349756546 0.479858202 0.251512463 "LOS1 -- tRNA splicing -- Transport receptor for tRNA, member of karyopherin-beta family" YKR099W BAS1 1 12 3.1 0.6294 0.356852022 iYKR098C 0.361025784 0.367438324 0.268611022 "BAS1 -- histidine, adenine biosynthesis -- Transcription factor involved in regulation of basal and induced activity of histidine and adenine biosynthesis genes" YLR088W GAA1 1 12 3.1 0.6294 0.278671461 iYLR087C 0.439511424 0.579495039 0.609893651 "GAA1 -- protein processing -- Probable component, with Gpi8p, of a glycosylphosphatidylinositol (GPI) transamidase involved in the attachment of GPI anchors to proteins" YLR336C SGD1 1 12 3.1 0.6294 0.208476559 iYLR336C YLR337C 0.544703355 0.088850642 0.075043199 0.162124389 0.133447044 SGD1 -- signaling (putative) -- the Hog1p pathway YML108W YML108W 1 12 3.1 0.6294 0.421192777 iYML109W 0.586174366 0.556664006 0.551013277 YML108W -- unknown -- unknown function YPR131C NAT3 1 13 3.1 0.6294 0.97777482 iYPR131C 0.978777689 0.588374451 0.063725095 NAT3 -- protein processing -- N-acetyltransferase YER186C YER186C 0.9 11 3.1 0.6294 0.529425757 iYER186C YERComega1 0.393573506 0.709729267 0.829600387 0.605118078 0.385419238 YER186C -- unknown -- unknown function YNL181W YNL181W 0.9 11 3.1 0.6294 0.358311027 iYNL182C 0.441682709 0.427410901 0.491977923 YNL181W -- unknown -- unknown function YHR127W HSN1 0.8 10 3.1 0.6294 0.284433421 iYHR126C 0.233181345 0.417096358 0.167708685 HSN1 -- unknown -- High-copy allele-specific suppressor SEC4 YLR073C YLR073C 0.8 9 3.1 0.6294 0.651931856 iYLR073C 0.770769463 0.605140187 0.3946116 YLR073C -- unknown -- unknown function YOR073W YOR073W 0.8 9 3.1 0.6294 0.425194951 iYOR072W-0 iYOR072W-1 0.264266341 0.405852804 0.621628093 0.543828553 0.419723969 YOR073W -- unknown -- unknown function YCL025C AGP1 1.8 22 3 0.6195 1 0.710335204 iYCL025C 0.93869021 0.434317638 0.297406905 AGP1 -- transport -- Broad substrate range amino acid permease with high affinity for asparagine and glutamine YLR104W YLR104W 1.2 16 3 0.6195 1 0.961597792 iYLR103C 0.976071294 0.342994807 0.71124718 YLR104W -- unknown -- unknown function YBL020W RFT1 1 13 3 0.6195 1 0.894994051 iYBL021C 0.951460901 0.834879406 0.56473133 RFT1 -- cell cycle -- nuclear division YCR002C CDC10 2.7 34 3 0.6195 0.738489504 iYCR002C 0.598642436 0.960423256 0.68499601 "CDC10 -- cytokinesis -- Septin, component of 10 nm filaments of mother-bud neck, involved in cytokinesis" YLR261C YLR261C 2.2 27.5 3 0.6195 0.335385506 0.522044904 YLR261C -- unknown -- unknown function YNL099C YNL099C 2 24 3 0.6195 0.336404851 iYNL099C 0.27636565 0.427361458 0.160865157 YNL099C -- unknown -- similarity to protein tyrosine phosphatases (PTPs) YDR178W SDH4 1.9 24 3 0.6195 0.41755201 iYDR177W 0.216549244 0.947953593 0.193570929 "SDH4 -- TCA cycle, oxidative phosphorylation -- Membrane anchor subunit in the succinate dehydrogenase complex" YKL135C APL2 1.9 23 3 0.6195 0.590464466 iYKL135C 0.255040976 0.774062251 0.396671173 "APL2 -- secretion -- Beta-adaptin, large subunit of clathrin-associated protein (AP) complex" YPR133C YPR133C 1.9 23 3 0.6195 0.146293888 iYPR133C YPR133W-A 0.384154817 0.664162039 0.093695132 0.12159072 0.454489867 YPR133C -- unknown -- unknown function YBR279W PAF1 1.8 22 3 0.6195 0.099175143 iYBR278W 0.176057333 0.112632936 0.279180447 "PAF1 -- transcription -- associated with RNA polymerase II, involved in positive and negative regulation" YLR069C MEF1 1.8 22 3 0.6195 0.260109329 iYLR069C 0.683339716 0.610482802 0.30838106 "MEF1 -- protein synthesis -- Mitochondrial translation elongation factor G, promotes GTP-dependent translocation of nascent chain from A-site to P-site of ribosome" YPR072W NOT5 1.8 22 3 0.6195 0.44265573 iYPR071W tS(UGA)P 0.845194254 0.838982699 0.418326345 0.835102444 0.277458601 NOT5 -- transcription -- negatively regulates transcription of TATA-less promoters and has similarity to Not3p YGL022W STT3 1.7 22 3 0.6195 0.657673712 iYGL023C 0.050895039 0.588268156 0.105323788 "STT3 -- protein glycosylation -- Oligosaccharyltransferase subunit, member of a complex of eight ER proteins that transfers core oligosaccharide from dolichol carrier to Asn-X-Ser/Thr motif" YKR065C YKR065C 1.7 20 3 0.6195 0.150987433 iYKR065C 0.217607458 0.356026426 0.136403969 YKR065C -- unknown -- unknown function YMR022W UBC7 1.7 22 3 0.6195 0.525765542 iYMR021C 0.481649125 0.850978337 0.601216627 "UBC7 -- protein degradation, ubiquitin-mediated -- Ubiquitin-conjugating enzymeassociates with Ubc6p on the cytoplasmic side of endoplasmic reticulum" YKR038C YKR038C 1.6 19 3 0.6195 0.378786018 iYKR038C itD(GUC)K 0.450800544 0.532839299 0.852763578 0.364201016 0.402483892 YKR038C -- unknown -- similarity to Qri7p and Pasteurella haemolytica glycoproteinase YOL158C ENB1 1.6 19 3 0.6195 0.534220995 iYOL158C 0.614695567 0.448806072 0.68419779 ENB1 -- unknown -- iron uptake via a siderophore enterobactinmember of yeast-specific putative multidrug-resistance family of major facilitator superfamily (MFS) YOR311C YOR311C 1.6 20 3 0.6195 0.132050708 iYOR311C 0.70778073 0.278508772 0.441266516 YOR311C -- unknown -- unknown function YDR105C YDR105C 1.5 17 3 0.6195 0.490111212 iYDR105C 0.173825663 0.823396713 0.19479385 YDR105C -- unknown -- unknown function YBL017C PEP1 1.3 16 3 0.6195 0.408128387 iYBL017C 0.413701706 0.416440385 0.443735036 PEP1 -- vacuolar protein targeting -- Receptor for vacuolar sorting of carboxypeptidase Y and soluble vacuolar proteins YGR074W SMD1 1.3 17 3 0.6195 0.405553004 0.61198381 "SMD1 -- mRNA splicing -- Spliceosomal snRNA-associated Sm core protein, also associated with telomerase TLC1 RNA" YJL140W RPB4 1.3 17 3 0.6195 0.203241008 iYJL141C 0.289284931 0.11845218 0.386303138 "RPB4 -- transcription -- RNA polymerase II, fourth-largest subunit (B32), non-essential subunit that confers stress tolerance" YNL090W RHO2 1.3 16 3 0.6195 0.499550057 iYNL091W 0.319710264 0.739692464 0.364324847 "RHO2 -- signaling -- GTP-binding protein, member of rho family in the ras superfamily" YGR276C RNH70 1.2 15 3 0.6195 0.293600182 iYGR276C 0.454766867 0.75445898 0.049387689 "RNH70 -- DNA replication (putative) -- Ribonuclease H (70 kDa), endonuclease that degrades RNA in RNA-DNA hybrids" YJR014W YJR014W 1.2 16 3 0.6195 0.304884869 iYJR013W 0.324848573 0.066520468 0.007340486 YJR014W -- unknown -- similarity to human DENR/DRP density-regulated protein YKL167C MRP49 1.2 15 3 0.6195 0.831470815 iYKL167C 0.088177816 0.8851335 0.159681611 "MRP49 -- protein synthesis -- Mitochondrial ribosomal large subunit," YKL174C YKL174C 1.2 16 3 0.6195 0.583145333 iYKL174C 0.216426942 0.259856345 0.080925778 YKL174C -- unknown -- similarity to Hnm1p and other permeases YKR002W PAP1 1.2 15 3 0.6195 0.226168315 iYKR001C 0.50700822 0.342755036 0.715920077 "PAP1 -- mRNA polyadenylation -- Poly(A) polymerase, required for mRNA 3' end formation, has a poorly conserved RNA recognition (RRM) domain" YKR056W TRM2 1.2 16 3 0.6195 0.884862472 iYKR055W 0.389944763 0.876424349 0.29737351 TRM2 -- unknown -- Uridine methyltransferase that catalyzes the formation of ribothymidine at position 54 in cytoplasmic and mitochondrial tRNA YLR459W CDC91 1.2 15 3 0.6195 0.541117874 iYLR458W 0.351285712 0.782407407 0.623619233 CDC91 -- unknown -- unknown function YOR002W ALG6 1.2 16 3 0.6195 0.270771069 iYOR001W 0.421979259 0.660742204 0.552794022 ALG6 -- protein glycosylation -- Glucosyltransferase involved in the synthesis of dolichol-linked oligosaccharide precursor YPL023C MET12 1.2 15 3 0.6195 0.269163837 iYPL023C 0.082992882 0.518449887 0.068240413 "MET12 -- methionine biosynthesis -- Methylenetetrahydrofolate reductase (MTHFR), involved in methionine biosynthesis" YPL210C SRP72 1.2 16 3 0.6195 0.443758107 iYPL210C 0.464348558 0.484916201 0.399371576 SRP72 -- secretion -- Signal recognition particle subunit YDR116C YDR116C 1.1 14 3 0.6195 0.172457044 iYDR116C 0.145983477 0.44942348 0.546130449 YDR116C -- unknown -- similarity to prokaryotic ribosomal protein L1 YDR275W YDR275W 1.1 13 3 0.6195 0.860695168 iYDR274C 0.440126783 0.770831653 0.306606962 YDR275W -- unknown -- unknown function YGL213C SKI8 1.1 14 3 0.6195 0.528102243 iYGL213C 0.412285552 0.870731507 0.318315788 "SKI8 -- meiosis, recombination -- meiotic recombination and in protection from double-stranded RNA (dsRNA) virusesmember of WD (WD-40) repeat family" YJL061W NUP82 1.1 13 3 0.6195 0.388864175 iYJL062W 0.823377044 0.522719948 0.218276137 NUP82 -- nuclear protein targeting -- Nuclear pore protein (nucleoporin)required for export of poly(A)+ RNA YJR088C YJR088C 1.1 13 3 0.6195 0.887719336 iYJR088C 0.19652921 0.955155106 0.41833807 YJR088C -- unknown -- unknown function YNL291C MID1 1.1 14 3 0.6195 0.494942119 iYNL291C 0.413980677 0.529165324 0.225458899 MID1 -- transport -- Putative Ca2+ channel component YKL019W RAM2 1 12 3 0.6195 0.615321055 iYKL020C 0.078888847 0.794947617 0.282836864 "RAM2 -- protein processing -- farnesyltransferase, alpha subunit, shared between farnesyltransferase (FTase) and geranylgeranyltransferase type I (GGTase I)" YPL146C YPL146C 1 13 3 0.6195 0.144014261 iYPL146C 0.670104794 0.222634508 0.706761006 YPL146C -- unknown -- unknown function YJR112W NNF1 0.9 11 3 0.6195 0.145784687 iYJR111C 0.559054504 0.301321302 0.509708549 NNF1 -- mitosis -- nuclear envelope required for proper nuclear morphology and nuclear migration during mitosis YLL004W ORC3 0.9 11 3 0.6195 0.571657188 iYLL005C 0.274780931 0.7691402 0.42514363 "ORC3 -- DNA replication -- Origin recognition complex (ORC), 62 kDa subunit" YMR259C YMR259C 0.9 11 3 0.6195 0.174207775 iYMR259C 0.540749013 0.4663869 0.81556265 "YMR259C -- unknown -- unknown function, has a peroxisomal targeting signal" YMR312W YMR312W 0.9 12 3 0.6195 0.35762419 iYMR311C 0.378471088 0.540529565 0.386480825 YMR312W -- unknown -- unknown function YOL056W GPM3 0.9 11 3 0.6195 0.223895458 iYOL057W 0.640142125 0.207439896 0.483285417 GPM3 -- glycolysis -- Phosphoglycerate mutasehas similarity to Gpm1p and Gpm2p YPL172C COX10 0.9 11 3 0.6195 0.469128517 iYPL172C 0.63337525 0.727886119 0.681649206 COX10 -- respiration -- Farnesyl transferase required for heme A synthesis YAL046C YAL046C 0.8 10 3 0.6195 0.750040473 iYAL046C 0.496752983 0.792535706 0.54993241 YAL046C -- unknown -- unknown function YBL028C YBL028C 0.8 10 3 0.6195 0.956253361 iYBL028C 0.982135054 0.866493225 0.831935709 YBL028C -- unknown -- unknown function YEL032W MCM3 0.8 9 3 0.6195 0.646100575 itS(AGA)E 0.097325317 0.594135802 0.007824474 "MCM3 -- DNA replication -- Member of MCM/P1 family, part of MCM complex that assembles at ARS elements to initiate replication" YLR437C YLR437C 1.5 18 2.9 0.6083 1 0.919657581 iYLR437C 0.969247087 0.118250752 0.169567421 YLR437C -- unknown -- unknown function YNL216W RAP1 0.9 12 2.9 0.6083 1 0.921957156 iYNL217W 0.970484452 0.925925926 0.164849021 "RAP1 -- transcription -- DNA-binding repressor and activator activities, also involved in silencing at telomeres and silent mating type loci" YLR248W RCK2 2.8 35 2.9 0.6083 0.593171811 iYLR247C 0.104758594 0.742265549 0.229046975 RCK2 -- unknown -- Calcium/calmodulin-dependent serine/threonine protein kinase (CaM kinase) YDL235C YPD1 2 26 2.9 0.6083 0.605688718 iYDL235C 0.423779953 0.348471404 0.246430588 YPD1 -- signaling -- Phosphorelay proteinfunctions between Sln1p and Ssk1p in a two-component system in the high-osmolarity sensing MAP kinase pathway YGL238W CSE1 1.7 21 2.9 0.6083 0.646275727 0.718498228 "CSE1 -- mitosis, chromosome segregation -- Karyopherin-beta involved in the nuclear export of karyopherin-alpha, possible kinetochore interacts with centromeric element CDEII" YOR008C SLG1 1.7 22 2.9 0.6083 0.176063454 iYOR008C 0.462360716 0.219891909 0.473985642 "SLG1 -- signaling, stress response and cell wall integrity -- Plasma membrane maintenance of cell wall integrity and for the stress response during vegetative growth" YBR173C UMP1 1.6 20 2.9 0.6083 0.190841342 iYBR173C 0.210537106 0.415646149 0.057504873 "UMP1 -- protein degradation, ubiquitin-mediated -- Proteasome maturation factorchaperone involved in proteasome assembly" YDR135C YCF1 1.5 18 2.9 0.6083 0.524901086 iYDR135C 0.776735094 0.295248078 0.635040402 "YCF1 -- transport -- Vacuolar glutathione S-conjugate transporter, member of ATP-binding cassette (ABC) superfamily" YER064C YER064C 1.5 19 2.9 0.6083 0.784458339 iYER064C 0.676218817 0.645882068 0.841927167 "YER064C -- unknown -- similarity to members of a putative transporter family that includes Ybr089p, Yer064p, Yer119p, Yil088p, Ykl146p, and Ynl101p" YJL042W MHP1 1.5 18 2.9 0.6083 0.296584559 iYJL043W 0.67781985 0.437444543 0.196718648 "MHP1 -- cytoskeleton -- Microtubule-interacting protein, related functionally to Drosophila 250 kDa microtubule-associated protein" YPL204W HRR25 1.5 19 2.9 0.6083 0.337976493 0.197030778 HRR25 -- DNA repair -- Casein kinase I (serine/threonine/tyrosine protein kinase) involved in DNA repair and meiosis YBR133C HSL7 1.3 17 2.9 0.6083 0.307373212 0.786819207 HSL7 -- cell cycle -- Negative regulatory Swe1p protein kinase YDR016C DAD1 1.3 17 2.9 0.6083 0.199212155 iYDR016C 0.095423351 0.174029555 0.182004265 DAD1 -- unknown -- unknown function YDR507C GIN4 1.3 17 2.9 0.6083 0.420949723 iYDR507C 0.241873139 0.511971269 0.095310989 "GIN4 -- cell cycle (growth inhibitor) -- Serine/threonine-protein kinase required for septin organization at the bud neck, has similarity to Ycl024p" YER125W RSP5 1.3 17 2.9 0.6083 0.488971109 iYER124C 0.435684358 0.890461216 0.410598206 "RSP5 -- protein degradation, ubiquitin-mediated -- Ubiquitin-protein ligase" YGR009C SEC9 1.3 17 2.9 0.6083 0.415661832 iYGR009C 0.360322167 0.709797679 0.34660814 SEC9 -- secretion -- Component of a t-SNARE complex on the plasma membraneinvolved in vesicle docking and secretion YJR161C COS5 1.3 18 2.9 0.6083 0.932827277 iYJR161C 0.995868141 0.681245012 0.364116309 COS5 -- unknown -- Member of COS family of subtelomerically-encoded proteins YMR189W GCV2 1.3 17 2.9 0.6083 0.629236182 iYMR188C 0.142510098 0.829278118 0.229938272 "GCV2 -- amino acid metabolism -- Glycine decarboxylase pyridoxal phosphate containing P subunit (glycine cleavage P protein), functions in the pathway for glycine degradation" YMR303C ADH2 1.3 17 2.9 0.6083 0.677362934 iYMR303C 0.394199571 0.521036387 0.352582846 "ADH2 -- glycolysis -- Alcohol dehydrogenase II, oxidizes ethanol to acetaldehydeexpression is repressed by glucose" YOR226C ISU2 1.3 17 2.9 0.6083 0.315232103 iYOR226C 0.085332463 0.415610786 0.085670835 ISU2 -- iron homeostasis -- similarity to iron-sulfur cluster nitrogen fixation proteins YPL026C SHA3 1.3 17 2.9 0.6083 0.202640776 iYPL026C 0.223198207 0.067278532 0.254981044 SHA3 -- glucose transport (putative) -- Serine/threonine protein kinase that suppresses the growth defect of snf3 mutants on low glucose YEL047C YEL047C 1.2 16 2.9 0.6083 0.373979092 iYEL047C 0.825984537 0.680526736 0.567505914 YEL047C -- unknown -- Cytoplasmic soluble fumarate reductase YER020W GPA2 1.2 16 2.9 0.6083 0.511786399 iYER019C-A 0.30579423 0.846761199 0.717128585 GPA2 -- signaling -- Guanine nucleotide-binding protein alpha subunit involved in regulation of cAMP pathway YER063W THO1 1.2 17 2.9 0.6083 0.616126698 iYER062C 0.413223122 0.798568255 0.568240413 THO1 -- transcription (putative) -- suppresses hpr1 mutation YGR005C TFG2 1.2 17 2.9 0.6083 0.291342588 iYGR005C 0.475248393 0.35081068 0.904879454 "TFG2 -- transcription -- RNA polymerase II transcription initiation factor TFIIF (factor g)54 kDa subunit, component of RNA polymerase holoenzyme complex" YMR033W ARP9 1.2 16 2.9 0.6083 0.600319034 iYMR032W 0.547467838 0.817536501 0.564776023 "ARP9 -- cytoskeleton (putative) -- Component of SWI-SNF global transcription activator complex and RSC chromatin remodeling complex, acts to assist gene-specific activators through chromatin remodeling" YNL048W ALG11 1.2 16 2.9 0.6083 0.190788409 iYNL049C 0.304094532 0.483122426 0.434789764 ALG11 -- protein glycosylation -- N-linked oligosaccharide assembly YPR188C YPR188C 1.2 16 2.9 0.6083 0.152663753 iYPR188C 0.432707104 0.388268156 0.540050012 YPR188C -- unknown -- similarity to calmodulin and calmodulin-related proteins YCR057C 1.1 15 2.9 0.6083 0.514782751 iYCR057C 0.516900673 0.669378866 0.559856345 YDL002C NHP10 1.1 15 2.9 0.6083 0.096961692 iYDL002C 0.59180924 0.082259104 0.447608292 NHP10 -- chromatin structure -- Probable DNA-binding n HMG-box DNA-binding domain YER080W YER080W 1.1 15 2.9 0.6083 0.884197231 iYER079W 0.611512498 0.960716302 0.461778985 YER080W -- unknown -- unknown function YHR076W YHR076W 1.1 15 2.9 0.6083 0.370966335 iYHR075C 0.31943465 0.527194931 0.271269739 YHR076W -- unknown -- unknown function YHR187W IKI1 1.1 14 2.9 0.6083 0.322081917 iYHR186C 0.474843113 0.196902476 IKI1 -- killer toxin sensitivity -- sensitivity to pGKL killer toxin YJL041W NSP1 1.1 15 2.9 0.6083 0.481543556 iYJL042W 0.654259722 0.34839074 0.494173982 NSP1 -- nuclear protein targeting -- Nuclear pore protein (nucleoporin) with XFXFG motifs YLR090W XDJ1 1.1 15 2.9 0.6083 0.143165838 iYLR089C 0.026699819 0.308479532 0.14679503 XDJ1 -- unknown -- Homolog of E. coli DnaJ YLR241W YLR241W 1.1 14 2.9 0.6083 0.234881535 iYLR240W 0.283954627 0.757716049 0.259783368 YLR241W -- unknown -- unknown function YLR405W YLR405W 1.1 14 2.9 0.6083 0.749460664 iYLR404W 0.903404396 0.835596149 0.795037061 YLR405W -- unknown -- unknown function YGR001C YGR001C 1 12.5 2.9 0.6083 0.536157199 iYGR001C 0.173002585 0.862729449 0.215517241 YGR001C -- unknown -- unknown function YIL110W YIL110W 1 12 2.9 0.6083 0.411519399 iYIL111W 0.504532945 0.94243536 YIL110W -- unknown -- unknown function YJR057W CDC8 1 12 2.9 0.6083 0.913342595 iYJR056C itY(GUA)J2 0.084391002 0.628386515 0.704708699 0.034723936 0.417197709 CDC8 -- DNA replication -- Thymidylate kinase involved in dTTP biosynthesis pathway YJR100C YJR100C 1 13 2.9 0.6083 0.424050677 iYJR100C itL(UAG)J 0.694910399 0.565460757 0.598293042 0.649109015 0.506284241 "YJR100C -- unknown -- unknown function, has similarity to mouse TRA1/NOR1 proteins" YOL052C SPE2 1 13 2.9 0.6083 0.72581191 iYOL052C 0.724410666 0.666747888 0.5896249 "SPE2 -- polyamine metabolism -- S-adenosylmethionine decarboxylase, post-translationally cleaved into alpha and beta chains" YPR008W YPR008W 1 13 2.9 0.6083 0.604137442 iYPR007C YPRCdelta13 0.517242556 0.542050384 0.378589649 0.255147646 0.43485975 YPR008W -- unknown -- similarity to Cup2p and Candida albicans metal-activated transcription factor Amt1p YPR109W YPR109W 1 12 2.9 0.6083 0.786083543 iYPR108W tT(UGU)P 0.58354759 0.788126062 0.873700455 0.699000967 0.467039106 YPR109W -- unknown -- unknown function YDL063C YDL063C 0.9 12 2.9 0.6083 0.748848526 0.838365717 YDL063C -- unknown -- unknown function YDR517W GRH1 0.9 11 2.9 0.6083 0.715497622 iYDR516C 0.247189943 0.807363841 0.383963862 "GRH1 -- unknown -- Component of spindle checkpoint, has similarity to mammalian GRASP proteins" YGR047C TFC4 0.9 11 2.9 0.6083 0.279991647 iYGR047C 0.40001728 0.730821973 0.411456573 "TFC4 -- transcription -- RNA polymerase transcription III initiation factor TFIIIC (tau), 131 kDa subunit, has 11 tetratricopeptide (TPR) repeats" YKL014C YKL014C 0.9 12 2.9 0.6083 0.459408418 iYKL014C 0.40498234 0.539961328 0.780293265 YKL014C -- unknown -- unknown function YMR263W YMR263W 0.9 11 2.9 0.6083 0.236112228 iYMR262W 0.814850668 0.122685757 0.669403064 YMR263W -- unknown -- Component of Rpd3p-Sin3p histone deacetylase complex YBL107C YBL107C 0.8 10 2.9 0.6083 0.576378947 iYBL107C 0.753636949 0.731243663 0.331006183 YBL107C -- unknown -- unknown function YDL150W RPC53 0.8 10 2.9 0.6083 0.152907429 0.197206704 "RPC53 -- transcription -- RNA polymerase III, fourth-largest essential subunit (C53)" YGR251W YGR251W 0.8 10 2.9 0.6083 0.190955291 iYGR250C-0 iYGR250C-1 0.290386629 0.47485632 0.170802449 0.426554812 0.745011971 YGR251W -- unknown -- unknown function YHR062C RPP1 0.8 9 2.9 0.6083 0.555077444 iYHR062C 0.271283696 0.845365814 0.194732642 "RPP1 -- rRNA and tRNA processing -- Subunit of RNase P and RNase MRP ribonucleoprotein particles, which are needed for tRNA processing and 5.8S rRNA processing, respectively" YIL019W YIL019W 0.8 10 2.9 0.6083 0.989599035 iYIL020C 0.853729617 0.173068534 0.259336936 "YIL019W -- unknown -- unknown function, has potential coiled-coil region" YML061C PIF1 0.8 11 2.9 0.6083 0.597798654 iYML061C 0.772122532 0.440509801 0.77956816 "PIF1 -- DNA repair, mitochondrial -- Single-stranded DNA-dependent ATPase and 5'-3' DNA helicase required for maintenance and repair of mitochondrial DNA, also functions in nucleus to regulate telomere length" YPL066W YPL066W 0.8 11 2.9 0.6083 0.228957004 iYPL067C 0.474620106 0.026700008 0.53264166 YPL066W -- unknown -- unknown function YOR179C YOR179C 0.7 9 2.9 0.6083 0.359095483 iYOR179C-0 iYOR179C-1 0.773918963 0.952104741 0.245944576 0.681132532 0.168385433 YOR179C -- unknown -- similarity to Ysh1p YEL071W DLD3 1.6 21 2.8 0.5951 1 0.617478746 iYEL072W-0 iYEL072W-1 0.952496383 0.715987017 0.863926576 0.973586769 0.668627135 DLD3 -- unknown -- D-lactate dehydrogenase YOR043W WHI2 1.2 16 2.8 0.5951 1 0.860692893 iYOR042W SNR62 0.822757653 0.751633453 0.599174936 0.65408805 WHI2 -- cell size -- growth regulation YIL121W YIL121W 0.8 10 2.8 0.5951 1 0.893011028 iYIL122W 0.935970555 0.946922643 0.59187032 YIL121W -- unknown -- Member of multidrug-resistance 12-spanner family of major facilitator superfamily (MFS-MDR) YBR126C TPS1 2.8 38 2.8 0.5951 0.554554096 iYBR126C 0.235298098 0.713923829 0.256758078 "TPS1 -- trehalose metabolism -- Trehalose-6-phosphate synthase, component of trehalose-6-phosphate synthase/phosphatase complex" YJR117W STE24 2 27 2.8 0.5951 0.424843163 iYJR116W 0.379675605 0.690892958 0.177322472 STE24 -- protein processing -- Prenyl-dependent protease involved both in the first N-terminal proteolytic step and in C-terminal CAAX processing of a-factor YNL006W LST8 2 28 2.8 0.5951 0.626443512 iYNL007C 0.692632051 0.873437122 0.474415205 LST8 -- secretion -- transport of permeases from the Golgi to the plasma membrane YKR039W GAP1 1.9 25 2.8 0.5951 0.2528747 iYKR038C itD(GUC)K 0.450800544 0.532839299 0.746777312 0.364201016 0.402483892 "GAP1 -- transport -- General amino acid permease, proton symport transporter for all naturally-occuring L-amino acids, 4-aminobutyric acid (GABA), ornithine, citrulline, some D-amino acids, and some toxic analogs" YFL057C YFL057C 1.8 24 2.8 0.5951 0.739771543 0.742537909 "YFL057C -- unknown -- Putative aryl alcohol dehydrogenase, may participate in late steps of degradation of aromatic compounds that arise from the degradation of lignocellulose" YER090W TRP2 1.7 22 2.8 0.5951 0.589420492 iYER089C 0.553514023 0.79113541 0.663712536 TRP2 -- tryptophan biosynthesis -- Component I of anthranilate synthase YGR232W YGR232W 1.7 22 2.8 0.5951 0.879854569 iYGR231C 0.393658637 0.922735127 0.522465113 YGR232W -- unknown -- unknown function YPL053C KTR6 1.7 22 2.8 0.5951 0.280641271 iYPL053C 0.378822831 0.466564491 0.4562704 KTR6 -- protein glycosylation -- Mannosyltransferase of KRE2 family YNR076W PAU6 1.6 21 2.8 0.5951 0.928759267 iYNR075W 0.885073449 0.437118563 0.192548158 PAU6 -- unknown -- Member of seripauperin (PAU) family (YLL064C and PAU6 code for identical proteins) YKL007W CAP1 1.5 20 2.8 0.5951 0.702094142 iYKL008C 0.767560673 0.696422817 0.790191175 "CAP1 -- cytoskeleton -- Actin-capping protein, alpha subunit" YLR314C CDC3 1.5 19 2.8 0.5951 0.134092447 iYLR314C 0.543653259 0.127773344 0.495926434 "CDC3 -- cytokinesis -- Septin, component of 10 nm filaments of mother-bud neckinvolved in cytokinesis" YPL179W SAL6 1.5 19 2.8 0.5951 0.118852181 iYPL180W 0.548708509 0.133473096 0.404389465 SAL6 -- translational regulation -- Protein serine/threonine phosphatase involved in regulation of protein synthesismember of PPP family of protein phosphatases and related to PP1 phosphatases YPL232W SSO1 1.5 19 2.8 0.5951 0.441134826 iYPL233W 0.251966648 0.315251572 0.247718824 SSO1 -- secretion -- Syntaxin homolog (t-SNARE) involved in vesicle transport from Golgi to plasma membrane YBR198C TAF90 1.3 18 2.8 0.5951 0.414411216 iYBR198C 0.328981648 0.243502274 0.381243957 "TAF90 -- transcription -- Component of TAF(II) complex (TBP-associated protein complex) and SAGA complex (Spt-Ada-Gcn5-acetyltransferase)required for activated transcription by RNA polymerase II, member of WD (WD-40) repeat family" YDL074C YDL074C 1.3 17 2.8 0.5951 0.595834754 iYDL074C 0.417592839 0.508137286 0.772719948 "YDL074C -- unknown -- Putative coiled-coil protein, has similarity to human EEA1, an early endosome antigen" YFR037C RSC8 1.3 17 2.8 0.5951 0.297226783 iYFR037C 0.176896704 0.368448637 0.15412504 RSC8 -- chromatin structure -- Component of abundant chromatin remodeling complex (RSC) YGL252C RTG2 1.3 18 2.8 0.5951 0.419172644 iYGL252C 0.049700502 0.515470798 "RTG2 -- interorganelle communication -- inter-organelle communication between mitochondria, peroxisomes, and nucleus" YGR147C NAT2 1.3 18 2.8 0.5951 0.75094461 iYGR147C 0.702170767 0.732942233 0.524481729 NAT2 -- protein processing -- N-acetyltransferase for N-terminal methionine YHR103W SBE22 1.3 17 2.8 0.5951 0.351439706 iYHR102W 0.376906482 0.502427384 0.271348763 SBE22 -- bud growth -- bud growth YKR030W YKR030W 1.3 17 2.8 0.5951 0.457951259 iYKR029C 0.20933946 0.597047087 0.48262402 YKR030W -- unknown -- unknown function YML121W GTR1 1.3 17 2.8 0.5951 0.474192239 iYML122C 0.463110053 0.488932072 0.291814373 GTR1 -- phosphate transport -- GTP-binding the function of Pho84p phosphate transporter YAL008W YAL008W 1.2 16 2.8 0.5951 0.439636275 iYAL009W 0.258881422 0.448284118 0.251754457 YAL008W -- unknown -- unknown function YBR177C EHT1 1.2 16 2.8 0.5951 0.696137053 0.803258455 EHT1 -- unknown -- Alcohol acyl transferase YGL035C MIG1 1.2 16 2.8 0.5951 0.467090316 iYGL035C 0.156069949 0.549548824 0.314572534 "MIG1 -- glucose repression -- Zinc-finger transcriptional repressor involved in glucose-repression, has two tandem C2H2-type zinc fingers, has similarity to mammalian Sp1, Krox/Egr, and Wilms tumor proteins" YHR192W YHR192W 1.2 16 2.8 0.5951 0.465504496 iYHR191C 0.640907806 0.888320338 0.417278374 YHR192W -- unknown -- unknown function YKL110C KTI12 1.2 16 2.8 0.5951 0.381800025 iYKL110C-0 iYKL110C-1 0.291102111 0.279584621 0.862523303 0.805426975 0.236923327 KTI12 -- killer toxin resistance -- resistance to Kluyveromyces lactis killer toxin YKR001C VPS1 1.2 17 2.8 0.5951 0.541614213 iYKR001C 0.50700822 0.740734773 0.715920077 "VPS1 -- vacuolar protein targeting -- Vacuolar sorting protein, member of dynamin family of GTPases" YDL116W NUP84 1.1 15 2.8 0.5951 0.739463133 iYDL117W 0.707861206 0.324679831 0.613575933 NUP84 -- nuclear protein targeting -- Nuclear pore protein YDR121W DPB4 1.1 14 2.8 0.5951 0.213621312 iYDR120C 0.18605031 0.143256185 0.173866535 DPB4 -- DNA replication -- Protein subunit (29 kDa) of DNA Polymerase epsilon (Polymerase II) YDR140W YDR140W 1.1 14 2.8 0.5951 0.062475303 iYDR139C 0.149855978 0.147288735 0.235324948 YDR140W -- unknown -- motif characteristic of S-adenosylmethionine-dependent methyltransferases YDR281C PHM6 1.1 15 2.8 0.5951 0.687915668 iYDR281C 0.317192048 0.499930147 0.736226506 "PHM6 -- unknown -- unknown function, has a role in phosphate metabolism" YER005W YND1 1.1 14 2.8 0.5951 0.640787104 iYER004W 0.564865312 0.453109158 0.643883069 "YND1 -- protein glycosylation (putative) -- Membrane-bound apyrase (nucleotide diphosphatase) required for N-linked and O-linked glycosylation, has similarity to Gda1p" YER019W YER019W 1.1 14 2.8 0.5951 0.444006753 iYER018C 0.128924161 0.847269419 0.040566115 "YER019W -- unknown -- moderate similarity to mammalian neutral sphingomyelinases, has motifs typical of ATP/GTP-binding sites" YER099C PRS2 1.1 14 2.8 0.5951 0.805245265 iYER099C 0.428307329 0.884421702 0.632472385 "PRS2 -- purine biosynthesis -- Phosphoribosylpyrophosphate synthetase (ribose-phosphate pyrophosphokinase), synthesizes phosphoribosylpyrophosphate (PRPP) from ribose-5' phosphate and ATP" YGR165W YGR165W 1.1 15 2.8 0.5951 0.63467821 itR(UCU)G2 0.399599412 0.82020953 0.389852384 YGR165W -- unknown -- unknown function YHR001W YHR001W 1.1 15 2.8 0.5951 0.745724642 iYHL001W CEN8 0.638889896 0.656293594 0.829439252 0.409050577 0.40911709 YHR001W -- unknown -- similarity to Ykr003p and members of oxysterol-binding protein family YLR018C YLR018C 1.1 15 2.8 0.5951 0.475456136 iYLR018C 0.434846148 0.522616609 0.398004789 YLR018C -- unknown -- Component of nuclear pore complex (nucleoporin) YMR208W ERG12 1.1 15 2.8 0.5951 0.323624061 iYMR207C 0.264869031 0.787367912 0.654106117 "ERG12 -- sterol metabolism -- Mevalonate kinase, generates mevalonate-5-phosphate from mevalonate" YNL163C YNL163C 1.1 14 2.8 0.5951 0.531468825 iYNL163C 0.976840993 0.591927167 0.86632083 YNL163C -- protein synthesis -- Translation elongation factor EF4 YBR070C SAT2 1 13 2.8 0.5951 0.401317581 iYBR070C 0.264988322 0.487471074 0.193272566 SAT2 -- stress response -- osmotolerance YDR498C SEC20 1 13 2.8 0.5951 0.597294095 iYDR498C 0.33257907 0.782105441 0.110429943 "SEC20 -- secretion -- Secretory pathway transport of proteins from ER to Golgicontains C-terminal HDEL motif, unusual for a membrane protein" YER113C YER113C 1 14 2.8 0.5951 0.691044553 iYER113C 0.221784776 0.927374302 0.157992565 YER113C -- unknown -- similarity to Emp70p YFL009W CDC4 1 14 2.8 0.5951 0.495713414 iYFL010C 0.611762802 0.779569034 0.669221492 "CDC4 -- cell cycle -- F-box protein and component of SCF-Cdc4p complex (Skp1p-Cdc53p-Cdc34p-Cdc4p) which targets Sic1p, Far1p, Cdc6p, Ctf13p and Gcn4p for ubiquitin-dependent degradation, has WD (WD-40) repeats" YGL111W YGL111W 1 13 2.8 0.5951 0.441372351 iYGL112C 0.161083016 0.481562703 0.154769578 YGL111W -- unknown -- unknown function YJL184W YJL184W 1 13 2.8 0.5951 0.141454068 iYJL185C 0.369670928 0.226283301 0.504548408 YJL184W -- unknown -- unknown function YKL074C MUD2 1 14 2.8 0.5951 0.153039576 iYKL074C 0.190215616 0.310908798 0.099903319 "MUD2 -- mRNA splicing -- involved early in pre-mRNA splicing, has one degenerate RNA recognition (RRM) domain" YNR022C YNR022C 1 13 2.8 0.5951 0.284904757 iYNR022C 0.472748721 0.728074773 0.259115035 YNR022C -- unknown -- unknown function YPL195W APL5 1 14 2.8 0.5951 0.521069976 iYPL196W 0.530756873 0.652835965 0.245246536 "APL5 -- vacuolar protein targeting -- Delta-adaptin, large subunit of clathrin-associated protein (AP) complex" YGL139W YGL139W 0.9 12 2.8 0.5951 0.358474767 iYGL140C 0.545811635 0.371513207 0.261612131 YGL139W -- unknown -- unknown function YIL104C YIL104C 0.9 12 2.8 0.5951 0.205937547 iYIL104C 0.554071556 0.558659218 0.568012842 YIL104C -- unknown -- unknown function YIL152W YIL152W 0.9 12 2.8 0.5951 0.276269806 iYIL153W 0.641212022 0.377554458 0.237307661 YIL152W -- unknown -- unknown function YJL098W SAP185 0.9 12 2.8 0.5951 0.530563037 iYJL099W 0.496184864 0.838382211 0.348211408 SAP185 -- cell cycle -- associates with and contributes to function of protein phosphatase Sit4p YJL128C PBS2 0.9 12 2.8 0.5951 0.792596265 iYJL128C-0 iYJL128C-1 0.28909649 0.370038461 0.880013286 0.465975479 0.486327337 PBS2 -- signaling -- MAP kinase kinase (MEK) activated by high osmolarity through the Sln1p-Ypd1p-Ssk1p two-component osmosensor and the Sho1p osmosensor YJL208C NUC1 0.9 12 2.8 0.5951 0.22322045 iYJL208C 0.067498707 0.499712005 0.085423893 "NUC1 -- mitochondrial recombination -- Nuclease with both DNase and RNase activity, major nuclease of mitochondria" YLR290C YLR290C 0.9 12 2.8 0.5951 0.617504093 iYLR290C 0.865114883 0.65325434 0.786838251 YLR290C -- unknown -- unknown function YLR348C DIC1 0.9 12 2.8 0.5951 0.639736572 0.776536313 "DIC1 -- transport -- Mitochondrial dicarboxylate transport protein, member of mitochondrial carrier family" YOL007C CSI2 0.9 12 2.8 0.5951 0.288848914 iYOL007C 0.231786998 0.321438621 0.119303057 CSI2 -- cell wall biogenesis -- chitin synthesis YDR097C MSH6 0.8 11 2.8 0.5951 0.211504893 iYDR097C 0.527453675 0.627170246 0.635434956 MSH6 -- DNA repair -- Component with Msh2p of DNA mismatch binding factorinvolved in repair of single base mismatches YGR017W YGR017W 0.8 11 2.8 0.5951 0.444574407 iYGR016W 0.727722649 0.516919111 0.824016853 YGR017W -- unknown -- unknown function YKL214C YKL214C 0.8 11 2.8 0.5951 0.977060814 iYKL214C 0.430424582 0.407853666 YKL214C -- unknown -- unknown function YOR081C YOR081C 0.8 10 2.8 0.5951 0.191937234 iYOR081C 0.136965044 0.432968095 0.204119183 YOR081C -- unknown -- unknown function YOR288C MPD1 0.8 11 2.8 0.5951 0.410093037 iYOR288C 0.572447103 0.538385584 0.525137826 MPD1 -- protein folding (putative) -- Potential protein disulfide isomerase YJL050W MTR4 0.7 9 2.8 0.5951 0.607040059 iYJL051W 0.433351622 0.42952913 0.072752175 "MTR4 -- mRNA export -- mRNA export from nucleus, member of DEAD-box RNA helicase family" YLR126C YLR126C 0.7 9 2.8 0.5951 0.122108978 iYLR126C 0.792522266 0.255626496 0.576916829 YLR126C -- unknown -- weak similarity to Pseudomonas aeroginosa anthranilate synthase component II YLR256W HAP1 1.1 15 2.7 0.5822 1 0.799147743 iYLR255C 0.923474956 0.526426039 0.12901318 "HAP1 -- transcription -- Transcription factor with heme-dependent DNA-binding activity, responsible for heme-dependent activation of many genes" YOR161C YOR161C 1.1 15 2.7 0.5822 1 0.448973732 iYOR161C 0.973227566 0.435197702 0.308966862 YOR161C -- unknown -- unknown function YCR082W YCR082W 3.6 49 2.7 0.5822 0.511030764 iYCR081W 0.418815099 0.836338532 0.612051077 YCR082W -- unknown -- similarity to Rbk1p YGR137W YGR137W 2.1 29 2.7 0.5822 0.406855172 0.625299282 YGR137W -- unknown -- similarity to tomato extensin PIR YGL195W GCN1 1.9 26 2.7 0.5822 0.55078842 iYGL196W 0.671777585 0.808263452 0.832812304 GCN1 -- protein synthesis -- Component of a protein complex required for activation of Gcn2p protein kinase in response to starvation for amino acids or purines YCR037C PHO87 1.8 24 2.7 0.5822 0.686271832 iYCR037C 0.128437114 0.7378398 0.123590883 PHO87 -- transport -- Member of phosphate permease family of membrane transporters YLL020C YLL020C 1.7 24 2.7 0.5822 0.449874625 0.225457772 YLL020C -- unknown -- unknown function YEL013W VAC8 1.6 21 2.7 0.5822 0.742998219 iYEL014C 0.674067952 0.799600958 0.56691135 VAC8 -- vacuolar protein targeting -- Vacuolar vacuolar inheritance and protein targeting from the cytoplasm to vacuole YIL116W HIS5 1.5 20 2.7 0.5822 0.588602926 iYIL117C 0.359909238 0.98219465 0.423702868 "HIS5 -- histidine biosynthesis -- Histidinol-phosphate aminotransferase (imidazole acetol phosphate aminotransferase), eighth step in histidine biosynthesis pathway" YJL053W PEP8 1.5 20 2.7 0.5822 0.618695947 iYJL054W 0.684485887 0.862004548 0.379285311 PEP8 -- vacuolar protein targeting -- vacuolar targeting YDR477W SNF1 1.3 18 2.7 0.5822 0.514635125 iYDR476C 0.226848083 0.691779729 0.597959352 SNF1 -- glucose derepression -- Serine/threonine protein kinase essential for derepression of glucose-repressed genesacts with Snf4p YIR034C LYS1 1.3 19 2.7 0.5822 0.449098637 iYIR034C 0.498395807 0.55888564 0.203673864 "LYS1 -- lysine biosynthesis -- Saccharopine dehydrogenase (NAD+, L-lysine forming)eighth and last step in lysine biosynthesis pathway" YLL012W YLL012W 1.3 19 2.7 0.5822 0.434252491 iYLL013C 0.224673608 0.711051031 0.171763966 YLL012W -- unknown -- similarity to human triacylglycerol lipase YLL023C YLL023C 1.3 18 2.7 0.5822 0.576712864 iYLL023C 0.493291697 0.742998612 0.668291098 YLL023C -- unknown -- unknown function YOL122C SMF1 1.3 18 2.7 0.5822 0.62069474 iYOL122C 0.71231305 0.701143751 0.899860117 SMF1 -- transport -- High-affinity manganese transporter YDR464W SPP41 1.2 16 2.7 0.5822 0.376376712 iYDR463W 0.591800521 0.243554625 0.354532164 "SPP41 -- splicing -- Suppressor of temperature-sensitive prp3, temperature-sensitive prp4, and prp11, probably a negative regulator of PRP3 and PRP4 gene expression" YHL020C OPI1 1.2 17 2.7 0.5822 0.097088095 iYHL020C 0.248317566 0.414798571 0.274993829 OPI1 -- phospholipid metabolism -- Negative regulator of phospholipid biosynthesis pathway YKL185W ASH1 1.2 17 2.7 0.5822 0.633920082 iYKL186C 0.441512475 0.592338388 0.3896249 "ASH1 -- mating type switching -- GATA-type transcription factor, negative regulator of HO expression localized preferentially in daughter cells" YML081W YML081W 1.2 17 2.7 0.5822 0.30348091 YML081C-A iYML081C-A 0.176107737 0.206755685 0.299629391 0.246938447 0.549788824 "YML081W -- unknown -- similarity to Zms1p and Adr1p, has two tandem C2H2-type zinc fingers" YML101C YML101C 1.2 17 2.7 0.5822 0.358461287 iYML101C 0.352351623 0.422403582 0.365936191 YML101C -- unknown -- unknown function YMR046C 1.2 17 2.7 0.5822 0.876755703 YMR046W-A 0.604311565 0.518637373 0.504389465 YPL105C YPL105C 1.2 16 2.7 0.5822 0.23067562 iYPL105C 0.525070017 0.161512928 0.77047087 YPL105C -- unknown -- similarity to Smy2p YBL079W NUP170 1.1 16 2.7 0.5822 0.597636017 iYBL080C 0.375361259 0.652012584 0.502643533 NUP170 -- nuclear protein targeting -- Nuclear pore protein (nucleoporin) with similarity to mammalian Nup155p YCR008W SAT4 1.1 15 2.7 0.5822 0.393400147 iYCR007C tN(GUU)C 0.813106626 0.48500876 0.514764565 0.927712801 0.175819534 SAT4 -- salt tolerance -- Serine/threonine protein kinase involved in sensitivity to salt YDL117W YDL117W 1.1 16 2.7 0.5822 0.679779828 iYDL118W 0.440630415 0.795051875 YDL117W -- unknown -- unknown function YDL164C CDC9 1.1 16 2.7 0.5822 0.318013182 0.355083857 "CDC9 -- DNA replication and repair -- DNA ligase, functions in DNA replication and repair in both the nucleus and mitochondrion" YDR251W PAM1 1.1 15 2.7 0.5822 0.722193174 iYDR250C 0.320325545 0.832540131 0.461582196 "PAM1 -- unknown -- Coiled-coil protein and multicopy suppressor of loss of PP2A (genes PPH21, PPH22, and PPH3)" YDR390C UBA2 1.1 15 2.7 0.5822 0.6462272 iYDR390C tG(CCC)D 0.297868528 0.587893189 0.78098521 0.228970471 0.157780108 "UBA2 -- protein degradation, ubiquitin-mediated -- Subunit of a heterodimeric enzyme consisting of Uba2p and Aos1p, activates the ubiquitin-like Smt3p for conjugation to other proteins" YER082C YER082C 1.1 15 2.7 0.5822 0.45455985 iYER082C 0.478348098 0.479996506 0.239909077 "YER082C -- unknown -- unknown function, has two tandem C2H2-type zinc fingers, has one WD (WD-40) domain" YHR206W SKN7 1.1 15 2.7 0.5822 0.445058308 iYHR205W 0.559389462 0.388414438 0.638114046 "SKN7 -- oxidative stress -- Transcription factor involved in oxidative stress response and G1 cell cycle control, has similarity to response regulator proteins of bacterial two-component systems" YKL062W MSN4 1.1 15 2.7 0.5822 0.42217502 iYKL063C-0 iYKL063C-1 0.450425784 0.905779505 0.706815985 0.213450292 "MSN4 -- transcription -- Zinc-finger transcriptional activator for genes regulated through Snf1p, has strong similarity to Msn2p, has two tandem C2H2-type zinc fingers" YKL076C YKL076C 1.1 15 2.7 0.5822 0.287904932 0.651402501 YKL076C -- unknown -- unknown function YMR093W YMR093W 1.1 16 2.7 0.5822 0.834063866 iYMR092C 0.898791799 0.731444533 0.098850963 "YMR093W -- unknown -- unknown function, has WD (WD-40) repeats" YNL137C NAM9 1.1 15 2.7 0.5822 0.376537752 iYNL137C 0.293057773 0.625935983 0.300748997 NAM9 -- protein synthesis -- Mitochondrial ribosomal small subunitmember of E. coli S4 superfamily YOL014W YOL014W 1.1 15 2.7 0.5822 0.644525126 iYOL015W 0.551540814 0.724451275 0.449403803 YOL014W -- unknown -- unknown function YPL020C ULP1 1.1 15 2.7 0.5822 0.422531225 iYPL020C 0.698381751 0.194173982 0.414205906 "ULP1 -- protein degradation -- Smt3p-specific protease, degrades conjugated ubiquitin-like protein Smt3p" YPL221W BOP1 1.1 16 2.7 0.5822 0.916203855 iYPL222W 0.475029241 0.536534506 0.142845633 BOP1 -- unknown -- unknown function YBR264C YPT10 1 14 2.7 0.5822 0.201257281 iYBR264C 0.458036438 0.60700559 0.58869572 YPT10 -- unknown -- member of rab family in the ras superfamily of small GTP-binding proteins YBR274W CHK1 1 14 2.7 0.5822 0.659779725 iYBR273C 0.401904817 0.943059327 0.643220134 "CHK1 -- cell cycle -- Checkpoint kinase, required for metaphase DNA-damage checkpoint" YER115C SPR6 1 14 2.7 0.5822 0.863867079 iYER115C 0.835146031 0.927148847 0.342491138 SPR6 -- sporulation -- Sporulation-specific protein YGL023C PIB2 1 14 2.7 0.5822 0.321006512 iYGL023C 0.050895039 0.581618843 0.105323788 "PIB2 -- signaling (putative) -- unknown function, has similarity to Fab1p and Vps27p" YGL056C SDS23 1 13 2.7 0.5822 0.306534026 iYGL056C 0.166284433 0.869071753 0.408395102 "SDS23 -- unknown -- Spindle pole body protein, has similarity to S. pombe sds23/moc1" YGL101W YGL101W 1 14 2.7 0.5822 0.745852058 iYGL102C 0.706060111 0.741627582 0.236397432 YGL101W -- unknown -- unknown function YHR191C CTF8 1 14 2.7 0.5822 0.166108361 iYHR191C 0.640907806 0.106743536 0.417278374 CTF8 -- mitosis (putative) -- unknown function YKL138C MRPL31 1 14 2.7 0.5822 0.327867546 iYKL138C 0.06210777 0.544187225 0.064937158 MRPL31 -- protein synthesis -- Mitochondrial ribosomal large subunit YLR036C YLR036C 1 13 2.7 0.5822 0.471500925 iYLR036C 0.273352083 0.480925778 0.448678698 YLR036C -- unknown -- unknown function YLR118C YLR118C 1 14 2.7 0.5822 0.105847183 iYLR118C 0.741149933 0.185916179 0.433814633 YLR118C -- unknown -- similarity to esterases YNL122C YNL122C 1 14 2.7 0.5822 0.699526299 iYNL122C 0.410918526 0.790998107 0.343988182 YNL122C -- unknown -- unknown function YOR048C RAT1 1 14 2.7 0.5822 0.345770401 iYOR048C 0.225596171 0.547601415 0.701150479 "RAT1 -- transcription -- 5'-3' exoribonuclease (exonuclease II), required for efficient nucleocytoplasmic RNA trafficking and for ribosomal RNA processing" YPR097W YPR097W 1 14 2.7 0.5822 0.250223617 iYPR096C 0.314670834 0.139461811 0.127369525 YPR097W -- unknown -- unknown function YAL022C YAL022C 0.9 12 2.7 0.5822 0.620736501 iYAL022C 0.034604874 0.940863033 0.073082197 "YAL022C -- unknown -- similarity to human equilibrative nucleoside transporters, has 11 potential transmembrane domains" YBR083W TEC1 0.9 13 2.7 0.5822 0.270730119 iYBR082C-0 iYBR082C-1 0.691274081 0.237478897 0.444946358 0.624203818 0.865054797 "TEC1 -- pseudohyphal growth -- Transcriptional activator, involved with Ste12p in pseudohyphal formation" YBR243C ALG7 0.9 13 2.7 0.5822 0.433946734 iYBR243C 0.593411041 0.729044834 0.796648045 ALG7 -- protein glycosylation -- UDP-N-acetyl-glucosamine-1-P transferase (GPT)ER transfers GlcNac-P from UDP-GlcNac to Dol-P YDR322W MRPL35 0.9 12 2.7 0.5822 0.42780491 iYDR321W 0.485003143 0.84302935 0.647988151 MRPL35 -- protein synthesis -- Mitochondrial ribosomal large subunit YGR093W YGR093W 0.9 12 2.7 0.5822 iYGR092W 0.820525533 0.633040702 YGR093W -- unknown -- unknown function YKL106W AAT1 0.9 12 2.7 0.5822 0.580577883 iYKL107W 0.73821965 0.955678587 0.657222666 "AAT1 -- aspartate metabolism? -- Putative aspartate aminotransferase, mitochondrial" YPR048W TAH18 0.9 13 2.7 0.5822 0.398332945 iYPR047W 0.473090612 0.76680655 0.292919905 TAH18 -- unknown -- similarity to NAPDH-cytochrome P450 reductase YBR112C SSN6 0.8 11 2.7 0.5822 0.401823621 0.390356291 SSN6 -- transcription -- General repressor of RNA polymerase II transcription that is brought to target promoters by sequence-specific DNA-binding proteinshas tetratricopeptide (TPR) repeats and exists in a complex with Tup1p YIL126W STH1 0.8 11 2.7 0.5822 0.793906354 iYIL127C 0.157529047 0.528756957 0.041300315 "STH1 -- chromatin structure -- Component of abundant chromatin remodeling complex (RSC), DNA helicase of Snf2p family, has a bromodomain" YLL021W SPA2 0.8 11 2.7 0.5822 0.085096872 iYLL022C 0.078223236 0.08424406 0.340063847 SPA2 -- cytoskeleton -- cell polarity and cell fusion during mating YMR157C YMR157C 0.8 12 2.7 0.5822 0.31674004 iYMR157C 0.58225271 0.699653277 0.488989272 YMR157C -- unknown -- unknown function YNR029C YNR029C 0.8 11 2.7 0.5822 0.848460487 iYNR029C 0.219911411 0.236303577 0.399720475 YNR029C -- unknown -- weak similarity to Rhodococcus sp. nitrile hydratase beta chain YOR239W YOR239W 0.8 11 2.7 0.5822 0.018930368 iYOR238W 0.161567104 0.074488337 0.057040531 YOR239W -- unknown -- unknown function YOR346W REV1 0.8 10 2.7 0.5822 0.736293023 0.278671215 REV1 -- DNA repair -- Deoxycytidyl transferaseinvolved in mutagenic translesion DNA synthesis YLR218C YLR218C 0.7 10 2.7 0.5822 0.062900705 iYLR218C 0.501014858 0.137753319 0.173268087 YLR218C -- unknown -- unknown function YMR225C MRPL44 1 14 2.6 0.5698 1 0.940911649 iYMR225C 0.801845556 0.520045514 0.662470172 MRPL44 -- protein synthesis -- Mitochondrial ribosomal large subunit (YmR44) YMR266W YMR266W 1 14 2.6 0.5698 1 0.528759751 iYMR265C 0.927593903 0.306014976 0.688798495 YMR266W -- unknown -- Possible membrane transporter involved in tunicamycin sensitivity YFL023W YFL023W 0.8 12 2.6 0.5698 1 0.719362705 iYFL024C 0.922211429 0.262487915 0.001949318 YFL023W -- unknown -- unknown function YMR121C RPL15B 1.6 23 2.6 0.5698 1 0.904306399 iYMR121C 0.220306073 0.829768555 0.318302815 "RPL15B -- protein synthesis -- Ribosomal protein L15 (yeast L13YL10rp15Rrat L15), nearly identical to Rpl15Ap" YML110C COQ5 2.5 35 2.6 0.5698 0.223330424 iYML110C 0.591982517 0.618675475 0.607082359 COQ5 -- ubiquinone biosynthesis -- Mitochondrial C-methyltransferase of ubiquinone biosynthetic pathway YKR071C YKR071C 2.4 34 2.6 0.5698 0.353520778 iYKR071C 0.310877026 0.809486373 0.240622506 YKR071C -- unknown -- unknown function YCR043C YCR043C 2 29 2.6 0.5698 0.309723788 iYCR043C 0.790120792 0.437865497 0.568977469 YCR043C -- unknown -- unknown function YCR077C PAT1 2 28 2.6 0.5698 0.557994693 iYCR077C 0.349354551 0.848614244 0.381564246 PAT1 -- mitosis; chromosome transmission -- faithful chromosome transmission and normal translation initiation YGR136W YGR136W 1.9 27 2.6 0.5698 0.488235104 iYGR135W 0.369361025 0.755829672 0.318570929 "YGR136W -- unknown -- weak similarity to chicken growth factor receptor-binding protein, has an SH3 domain" YFR052W RPN12 1.8 25 2.6 0.5698 0.615602225 iYFR051C 0.164495071 0.933176101 0.337984996 RPN12 -- protein degradation -- Non-ATPase component of 26S proteasome complexrequired for activation of Cdc28p protein kinase YGL167C PMR1 1.8 25 2.6 0.5698 0.411866399 iYGL167C 0.378854295 0.786077277 0.693063678 PMR1 -- transport -- Ca2+-transporting P-type ATPase of Golgi membrane involved in Ca2+ import into Golgi YKL013C ARC19 1.8 26 2.6 0.5698 0.219533508 iYKL013C 0.22366874 0.514523163 0.182681564 ARC19 -- cytoskeleton -- Component of ARP2/3 actin-organizing complexinvolved in actin assembly and function YNL192W CHS1 1.8 26 2.6 0.5698 0.383606185 iYNL193W 0.686654947 0.582681564 0.502336449 "CHS1 -- cytokinesis -- Chitin synthase I, has a repair function during cell separation" YOR257W CDC31 1.8 25 2.6 0.5698 0.047674237 iYOR256C 0.250858092 0.054302288 0.178887546 "CDC31 -- cytoskeleton -- Centrin, calmodulin-like calcium-binding spindle pole body, involved in first phase of spindle pole body duplication" YPL176C YPL176C 1.8 26 2.6 0.5698 0.392146696 iYPL176C 0.741214169 0.587614059 0.732597486 YPL176C -- unknown -- similarity to Ssp134p YPR191W QCR2 1.8 26 2.6 0.5698 0.212897665 iYPR190C 0.513001277 0.300999033 0.344359417 "QCR2 -- oxidative phosphorylation -- Ubiquinol cytochrome-c reductase core protein 2, component of ubiquinol cytochrome-c reductase complex (cytochrome bc1 complex)" YFR010W UBP6 1.7 24 2.6 0.5698 0.397231561 iYFR009W 0.422978203 0.514063592 0.179569034 "UBP6 -- protein degradation, ubiquitin-mediated -- Putative ubiquitin-specific protease, ubiquitin C-terminal hydrolase" YCL028W RNQ1 1.5 21 2.6 0.5698 0.371175084 iYCL029C 0.4459963 0.273677281 0.389040343 "RNQ1 -- unknown -- unknown function, may be required for resistance to certain drugs" YJL223C PAU1 1.5 21 2.6 0.5698 0.94173104 iYJL223C-0 iYJL223C-1 0.895785691 0.376250511 0.769768781 0.413791666 0.190164221 PAU1 -- unknown -- Member of seripauperin (PAU) family (PAU1 and YIL176C code for identical proteins) YER163C YER163C 1.3 18 2.6 0.5698 0.280867191 iYER163C-0 iYER163C-1 0.356008532 0.245960241 0.614251625 0.274582408 0.342168869 YER163C -- unknown -- unknown function YIL088C YIL088C 1.3 19 2.6 0.5698 0.327696275 iYIL088C 0.417712993 0.62037037 0.315066239 YIL088C -- unknown -- Putative membrane transporter of amino acid/auzin permease (AAAP) family YIL111W COX5B 1.3 18 2.6 0.5698 0.383632389 iYIL112W 0.448106761 0.489928525 0.684267479 "COX5B -- oxidative phosphorylation -- Cytochrome-c oxidase chain Vb, expressed under anaerobic conditions" YLR268W SEC22 1.3 19 2.6 0.5698 0.417892674 iYLR267W 0.463530969 0.597709552 0.279341952 SEC22 -- secretion -- Synaptobrevin (v-SNARE) homolog involved in fusion of ER-to-Golgi transport vesiclesrecognized by putative target t-SNARE (Sed5p) YML097C VPS9 1.3 20 2.6 0.5698 0.40976066 iYML097C 0.556336564 0.72501747 0.583271623 VPS9 -- vacuolar protein targeting -- vacuolar sorting YDR006C SOK1 1.2 17 2.6 0.5698 0.429938098 iYDR006C 0.55090115 0.364485235 0.346454787 SOK1 -- unknown -- can when overexpressed suppress mutants of cAMP-dependent protein kinase YDR031W YDR031W 1.2 18 2.6 0.5698 0.501973518 iYDR030C 0.284867273 0.395527603 0.194044702 YDR031W -- unknown -- unknown function YDR168W CDC37 1.2 17 2.6 0.5698 0.483036952 iYDR167W 0.288748567 0.793342537 0.313220941 CDC37 -- cell cycle -- Cell cycle spindle pole body duplication and passage through STARTinteracts with multiple protein kinase systems possibly as a targeting subunit YDR308C SRB7 1.2 17 2.6 0.5698 0.745798982 iYDR308C 0.437647951 0.983080607 0.440878795 SRB7 -- transcription -- Component of RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex YFR049W YMR31 1.2 17 2.6 0.5698 0.488241604 iYFR048W 0.41552961 0.590048196 0.163827861 YMR31 -- protein synthesis -- Mitochondrial ribosomal protein YHL017W YHL017W 1.2 18 2.6 0.5698 0.675344126 iYHL018W 0.256629616 0.952073211 0.115659519 YHL017W -- unknown -- strong similarity to Ptm1p YNR013C YNR013C 1.2 17 2.6 0.5698 0.144323795 iYNR013C 0.022490934 0.471667997 0.017300195 "YNR013C -- unknown -- similarity to Pho87p and Yjl198p, member of phosphate permease family of membrane transporters" YOL098C YOL098C 1.2 17 2.6 0.5698 0.312734378 iYOL098C SNR58 0.465521403 0.74345169 0.407823589 0.275099761 0.575129955 YOL098C -- unknown -- unknown function YOR262W YOR262W 1.2 17 2.6 0.5698 0.072577385 iYOR261C 0.176334806 0.058250081 0.351133339 YOR262W -- unknown -- unknown function YAL040C CLN3 1.1 16 2.6 0.5698 0.674289448 iYAL040C 0.893915714 0.419989478 0.181429071 CLN3 -- cell cycle -- G1/S-specific cyclin that interacts with Cdc28p protein kinase to control events at START YBL090W MRP21 1.1 16 2.6 0.5698 0.339519684 iYBL091C 0.8525615 0.699162101 0.691269645 MRP21 -- protein synthesis -- Mitochondrial ribosomal small subunit YCR046C IMG1 1.1 16 2.6 0.5698 0.458638029 iYCR046C 0.656851882 0.755908688 0.71541502 "IMG1 -- protein synthesis -- Putative mitochondrial ribosomal protein, essential for respiration and integrity of mitochondrial genome" YEL063C CAN1 1.1 16 2.6 0.5698 0.675099813 iYEL063C 0.605509133 0.356454883 0.527231711 "CAN1 -- transport -- Permease for basic amino acids, arginine, lysine, and histidine" YHR083W YHR083W 1.1 16 2.6 0.5698 0.664921478 iYHR082C 0.145986769 0.87563366 0.034677982 YHR083W -- unknown -- unknown function YIL098C FMC1 1.1 17 2.6 0.5698 0.095179635 iYIL098C 0.421690669 0.390901024 0.476526966 FMC1 -- respiration (putative) -- production or assembly of mitochondrial cytochromes YJR076C CDC11 1.1 16 2.6 0.5698 0.349605986 iYJR076C 0.35614315 0.535355148 0.441902049 "CDC11 -- cytokinesis -- Septin, component of 10 nm filaments of mother-bud neck, involved in cytokinesis" YKL213C DOA1 1.1 16 2.6 0.5698 0.189451941 iYKL213C 0.108148529 0.319674115 0.108799185 "DOA1 -- protein degradation, ubiquitin-mediated -- Protein required in ubiquitin proteolysis and found complexed with Cdc48p, has WD (WD-40) repeats" YBL011W SCT1 1 14 2.6 0.5698 0.555683752 0.843577717 SCT1 -- unknown -- Suppressor of a choline transport mutant YBR192W RIM2 1 14 2.6 0.5698 0.490705666 iYBR191W 0.79876915 0.561253802 0.811652035 RIM2 -- transport -- mitochondrial carrier (MCF) family that is required for respiration YLL036C PRP19 1 14 2.6 0.5698 0.668121774 iYLL036C 0.302500206 0.775259909 0.597384665 "PRP19 -- mRNA splicing; DNA repair -- Non-snRNP spliceosome component, also involved in mitotic recombination and gene conversion" YOL041C NOP12 1 14 2.6 0.5698 0.57412207 iYOL041C 0.553007041 0.386792453 0.258610908 NOP12 -- unknown -- unknown function YGL159W YGL159W 0.9 13 2.6 0.5698 0.58793063 iYGL160W 0.520801682 0.902513696 0.65638114 YGL159W -- unknown -- unknown function YGL196W YGL196W 0.9 12 2.6 0.5698 0.572521458 iYGL197W 0.463437262 0.946762116 0.849640862 YGL196W -- unknown -- unknown function YGR138C YGR138C 0.9 13 2.6 0.5698 0.375462693 iYGR138C 0.35767977 0.493494424 0.089814089 YGR138C -- unknown -- Member of multidrug-resistance 12-spanner family of major facilitator superfamily (MFS-MDR) YIL091C YIL091C 0.9 12 2.6 0.5698 0.303842306 iYIL091C 0.024172759 0.185868514 0.038015305 YIL091C -- unknown -- unknown function YMR001C CDC5 0.9 13 2.6 0.5698 0.360266103 iYMR001C 0.246608765 0.318851312 0.414924182 "CDC5 -- cell cycle -- Serine/threonine protein kinase required for exit from mitosismay be involved in operation of mitotic spindle, member of polo family of protein kinases" YMR044W IOC4 0.9 13 2.6 0.5698 0.07486426 iYMR043W 0.185063108 0.066601689 0.354279261 "IOC4 -- unknown -- unknown function, has glu-rich domains" YNL129W YNL129W 0.9 13 2.6 0.5698 0.076103123 iYNL130C 0.079974097 0.193308875 0.332487195 YNL129W -- unknown -- unknown function YNL169C PSD1 0.9 13 2.6 0.5698 0.350362604 iYNL169C 0.737266722 0.710655804 0.892907058 "PSD1 -- phospholipid metabolism -- Phosphatidylserine decarboxylase, mitochondrial isozyme, converts phosphatidyl-L-serine to phosphatidylethanolamine" YNR027W YNR027W 0.9 13 2.6 0.5698 0.224273345 iYNR026C 0.23286995 0.440545764 0.215782359 YNR027W -- unknown -- unknown function YOR160W MTR10 0.9 13 2.6 0.5698 0.508648184 iYOR159C 0.283022579 0.849822752 0.165108629 "MTR10 -- mRNA export -- Karyopherin-beta, involved in nuclear protein import and indirectly in mRNA transport from nucleus to cytoplasm" YPL112C YPL112C 0.9 13 2.6 0.5698 0.429544824 iYPL112C tM(CAU)P 0.577330501 0.688328293 0.221971374 0.150331936 0.365241636 YPL112C -- unknown -- unknown function YDR400W URH1 0.8 11 2.6 0.5698 0.824117614 iYDR399W 0.653855414 0.961205253 0.649610136 URH1 -- unknown -- Uridine ribohydrolase YDR539W YDR539W 0.8 12 2.6 0.5698 0.494337013 iYDR538W 0.330963557 0.898790422 0.252992817 YDR539W -- unknown -- unknown function YHR003C YHR003C 0.8 11 2.6 0.5698 0.624792693 iYHR003C 0.457362419 0.614116309 0.424022346 YHR003C -- unknown -- strong similarity to Ykl027p and weak similarity to E. coli thiF and moeB and to wheat ubiquitin-activating enzyme YOL110W SHR5 0.8 12 2.6 0.5698 0.982937016 iYOL111C 0.491089484 0.794783181 0.12244898 "SHR5 -- protein processing -- ras function, mutants can block attachment and palmitoylation of ras proteins" YOR280C YOR280C 0.8 11 2.6 0.5698 0.089433857 iYOR280C 0.363504058 0.202044025 0.417478882 YOR280C -- unknown -- similarity to N-terminal region of S. pombe dihydrofolate reductase YNL102W POL1 0.7 10 2.6 0.5698 0.817831015 iYNL103W 0.416758542 0.426146581 0.133419272 POL1 -- DNA replication -- DNA polymerase I alpha 180 kDa subunit YOR236W DFR1 0.7 10 2.6 0.5698 0.641188717 iYOR235W YOR235W 0.969447299 0.987736951 0.44161879 0.406920078 0.250625151 DFR1 -- folate biosynthesis -- Dihydrofolate reductase YLR399C BDF1 1.1 16 2.5 0.5597 1 0.946993909 iYLR399C 0.999391224 0.844134078 0.951762523 "BDF1 -- meiosis -- sporulation, has two bromodomain motifs and one ET domain" YDR186C YDR186C 1 16 2.5 0.5597 1 0.861345206 iYDR186C 0.966076436 0.613924036 0.005619232 YDR186C -- unknown -- unknown function YML130C ERO1 2 30 2.5 0.5597 0.493468324 iYML130C 0.457751556 0.572510474 0.280753633 ERO1 -- protein folding -- protein disulfide bond formation in the endoplasmic reticulum YBL038W MRPL16 1.9 28 2.5 0.5597 0.573369521 iYBL039C 0.370798854 0.718378756 0.241137609 "MRPL16 -- protein synthesis -- Mitochondrial ribosomal large subunit (YmL47E. coli L16), belongs to the L16 family of prokaryotic ribosomal proteins" YAL068C YAL068C 1.7 25 2.5 0.5597 0.916863296 iYAL068C-0 iYAL068C-1 0.911393119 0.708837723 0.283788174 0.255387071 0.651032667 YAL068C -- unknown -- Member of seripauperin (PAU) family YHR138C YHR138C 1.6 24 2.5 0.5597 0.35269091 iYHR138C 0.072464897 0.612622508 0.116495098 "YHR138C -- unknown -- vacuolar fusion, has sequence similarity to Pbi2p" YKR082W NUP133 1.6 24 2.5 0.5597 0.534687811 iYKR081C 0.716013722 0.75257815 0.617587295 NUP133 -- nuclear protein targeting -- Nuclear pore protein (nucleoporin) without peptide repeat elementsinvolved in export of poly(A)+ mRNA YNL058C YNL058C 1.6 24 2.5 0.5597 0.080378825 YNL058C -- unknown -- unknown function YLR429W CRN1 1.5 23 2.5 0.5597 0.201221963 0.311093376 "CRN1 -- cytoskeleton -- Coronin, actin-binding protein, contains WD (WD-40) repeats" YNL239W LAP3 1.3 21 2.5 0.5597 0.414375549 iYNL240C 0.157910853 0.71396648 0.182814799 "LAP3 -- protein degradation -- Aminopeptidase of cysteine protease family, homologous to rabbit bleomycin hydrolase" YBR135W CKS1 1.2 18 2.5 0.5597 0.279555541 iYBR134W 0.720521495 0.459788659 0.758942958 "CKS1 -- cell cycle -- associated with Cdc28p kinase, homolog of S. pombe suc1" YBR288C APM3 1.2 17 2.5 0.5597 0.61328706 iYBR288C 0.423925634 0.740475603 0.35497408 "APM3 -- vacuolar protein targeting -- Clathrin-associated protein (AP) complex, medium subunit" YIL066C RNR3 1.2 18 2.5 0.5597 0.56373251 iYIL066C 0.406835933 0.801332034 0.565459385 RNR3 -- DNA repair -- Ribonucleotide reductase (ribonucleoside-diphosphate reductase) large regulatory subunitconverts deoxyribonucleoside diphosphate to ribonucleoside diphosphate YLR120C YPS1 1.2 18 2.5 0.5597 0.65612942 iYLR120C 0.567755323 0.820125042 0.173702868 "YPS1 -- protein processing -- Yapsin 1, GPI-anchored aspartyl protease that cleaves C-terminal to paired basic residues (Aspergillopepsin I)" YMR010W YMR010W 1.2 19 2.5 0.5597 0.659569854 iYMR009W 0.407013486 0.819391788 0.401958364 YMR010W -- unknown -- unknown function YPR176C BET2 1.2 17 2.5 0.5597 0.122961648 iYPR176C 0.306406319 0.348874728 0.326719999 "BET2 -- protein processing -- Geranylgeranyltransferase Type II beta subunit, forms a complex with Bet4p" YDL076C YDL076C 1.1 17 2.5 0.5597 0.899639342 iYDL076C 0.973746268 0.203431764 0.106832098 YDL076C -- unknown -- unknown function YHL027W RIM101 1.1 16 2.5 0.5597 0.352675684 iYHL028W 0.322933682 0.529699511 0.170391061 "RIM101 -- meiosis -- Transcription factor involved in induction of IME1, IME2, DIT1, and DIT2 transcription" YNL330C 1.1 17 2.5 0.5597 0.690626518 iYNL330C 0.677820244 0.538526529 YAR003W YAR003W 1 15 2.5 0.5597 0.508895815 iYAR002C-A 0.286208291 0.68654951 0.666964234 "YAR003W -- unknown -- unknown function, contains a WD (WD-40) repeat" YCR044C YCR044C 1 16 2.5 0.5597 0.478597727 iYCR044C 0.624178253 0.550925926 0.570970131 "YCR044C -- unknown -- Suppressor of cdc1-1 temperature-sensitive growth defect, involved in Mn2+ homeostasis" YDR389W SAC7 1 15 2.5 0.5597 0.559351279 iYDR388W 0.140843646 0.696727853 0.219142765 SAC7 -- signaling -- GTPase-activating protein for Rho1p YEL015W YEL015W 1 15 2.5 0.5597 0.51972792 iYEL016C 0.452469332 0.610215483 0.661376088 YEL015W -- unknown -- unknown function YMR153W NUP53 1 15 2.5 0.5597 0.318297303 iYMR152W 0.451522403 0.402180814 0.487869114 NUP53 -- nuclear protein targeting -- Component of karyopherin docking complex of nuclear pore complexhas similarity to Asm4p YNL026W YNL026W 1 15 2.5 0.5597 0.356278967 iYNL027W 0.507839422 0.691280838 0.393893007 YNL026W -- unknown -- unknown function YNL039W TFC5 1 14 2.5 0.5597 0.207747262 iYNL040W 0.491249854 0.281189084 0.603060973 "TFC5 -- transcription -- Component of RNA polymerase III transcription factor TFIIIB, called B'' or TFIIIB90" YNL211C YNL211C 1 15 2.5 0.5597 0.316775311 iYNL211C 0.431966882 0.304699382 0.490496174 YNL211C -- unknown -- unknown function YOL088C MPD2 1 14 2.5 0.5597 0.144369552 iYOL088C 0.5694489 0.338946181 0.331856268 MPD2 -- unknown -- disulfide isomerase-related protein YDL042C SIR2 0.9 13 2.5 0.5597 0.560854094 0.546728972 "SIR2 -- silencing -- NAD-dependent histone deacetylase, involved in maintenance of silencing of HMR, HML and telomeres" YDR472W TRS31 0.9 13 2.5 0.5597 0.747621208 iYDR471W SNR13 0.84295058 0.7187819 0.849949307 0.760516494 0.182221505 TRS31 -- secretion (putative) -- TRAPP (Transport Protein Particle) complex involved in vesicular transport from endoplasmic reticulum to Golgi YGR262C YGR262C 0.9 13 2.5 0.5597 0.379773283 iYGR262C 0.480238095 0.938190383 0.709730957 YGR262C -- unknown -- similarity to apple tree calcium/calmodulin-binding protein kinase YHR115C YHR115C 0.9 14 2.5 0.5597 0.302686933 iYHR115C 0.197197223 0.511967156 0.286595902 YHR115C -- unknown -- unknown function YIL103W YIL103W 0.9 13 2.5 0.5597 0.394447143 iYIL104C 0.554071556 0.771994844 0.568012842 YIL103W -- unknown -- similarity to diptheria toxin resistance protein YPL128C TBF1 0.9 12 2.5 0.5597 0.150588524 iYPL128C 0.126342753 0.204489867 0.161213089 TBF1 -- telomere length regulation -- Teleomere binding proteinbinds to TTAGGG repeats YPR182W SMX3 0.9 13 2.5 0.5597 0.422002581 iYPR181C 0.595905382 0.222921034 0.198261858 "SMX3 -- mRNA splicing -- Spliceosomal snRNA-associated Sm core protein, also likely associated with telomerase TLC1 RNA" YBL111C YBL111C 0.8 12.5 2.5 0.5597 0.954121627 iYBL111C 0.997475409 0.854356949 0.376616121 YBL111C -- unknown -- unknown functionsubtelomerically encoded YHR218W YHR218W 0.8 22 2.5 0.5597 0.956723926 iYHR217C 0.995206987 0.774376585 0.159259885 "YHR218W -- unknown -- near identity to subtelomerically-encoded proteins including Yhr219p and Yfl065p, possible pseudogene" YKL073W LHS1 0.8 12 2.5 0.5597 0.614324305 iYKL074C 0.190215616 0.836976129 0.099903319 LHS1 -- secretion -- Hsp70 superfamily member required for efficient translocation of protein precursors across the ER membrane YLR077W YLR077W 0.8 12 2.5 0.5597 0.321734342 iYLR076C 0.412130886 YLR077W -- unknown -- unknown function YLR328W YLR328W 0.8 11 2.5 0.5597 0.634950168 iYLR327C tS(GCU)L 0.479010143 0.535666745 0.725104737 0.396401118 0.013239116 YLR328W -- unknown -- Nicotinamide mononucleotide (NMN) adenylyltransferase YMR233W YMR233W 0.8 11 2.5 0.5597 0.060703564 iYMR232W 0.590626149 0.111263294 0.344689029 YMR233W -- unknown -- similarity to Bud7p YOL006C TOP1 0.8 11 2.5 0.5597 0.081916788 iYOL006C 0.49632473 0.421130585 "TOP1 -- DNA replication -- DNA topoisomerase I, relaxes supercoiled DNA by making single-stranded breaks" YOL125W YOL125W 0.8 12 2.5 0.5597 0.709063277 iYOL126C 0.546030005 0.948195295 0.262753319 YOL125W -- unknown -- unknown function YOR264W YOR264W 0.8 11 2.5 0.5597 0.306340727 0.153988868 YOR264W -- unknown -- unknown function YFR036W CDC26 0.7 9 2.5 0.5597 0.287612658 iYFR035C itK(CUU)F 0.797412873 0.23155265 0.081062194 0.392120894 0.217172782 "CDC26 -- cell cycle -- Component of anaphase-promoting complex (APC), required for Clb2p degradation and for the metaphase-anaphase transition" YLR231C YLR231C 0.7 9 2.5 0.5597 0.183214085 0.388157895 YLR231C -- unknown -- weak similarity to rat kynureninase (PIR YML021C UNG1 0.7 10 2.5 0.5597 0.459711001 iYML021C 0.166907566 0.599143541 0.064047753 UNG1 -- DNA repair -- Uracil-DNA glycolyaseremoves uracil from DNA YML036W YML036W 0.7 10 2.5 0.5597 0.634047335 iYML037C 0.226989422 0.853851112 0.405826018 YML036W -- unknown -- unknown function YMR130W YMR130W 0.7 11 2.5 0.5597 0.770686682 iYMR129W 0.660080745 0.855543023 0.643167902 YMR130W -- unknown -- unknown function YDR310C SUM1 0.6 9 2.5 0.5597 0.413626732 iYDR310C 0.34114508 0.353074773 0.377355386 "SUM1 -- silencing -- middle sporulation element-mediated repression of SMK1, SPR3 and NDT80 during vegetative growth, suppressor of mar1-1 (sir2)" YHR040W YHR040W 0.6 9 2.5 0.5597 0.412512598 iYHR039C-B 0.412507617 0.374640007 0.22571475 "YHR040W -- unknown -- weak similarity to Hit1p, expressed under nitrogen-starvation conditions" YOR124C UBP2 1.3 20 2.4 0.5488 1 0.624929216 iYOR124C 0.982807296 0.377766807 0.775856045 "UBP2 -- protein degradation, ubiquitin-mediated -- Ubiquitin-specific protease (ubiquitin C-terminal hydrolase), cleaves at the C-terminus of ubiquitin" YLR452C SST2 0.9 14 2.4 0.5488 1 0.924525419 iYLR452C 0.990278156 0.832169495 0.927613727 SST2 -- mating -- desensitization to alpha-factor pheromone YGL058W RAD6 2 30 2.4 0.5488 0.381302944 iYGL059W 0.393397174 0.644577166 0.664744934 "RAD6 -- protein degradation, ubiquitin-mediated -- Ubiquitin conjugating enzyme involved in an error-prone DNA-damage recovery pathway" YER052C HOM3 1.9 29 2.4 0.5488 0.200259025 iYER052C 0.244771029 0.358183165 HOM3 -- Met. and Thr. biosynthesis -- Aspartate kinase (L-aspartate 4-P-transferase)first step in the common pathway for methionine and threonine biosynthesis YCL033C YCL033C 1.8 27 2.4 0.5488 0.145062302 iYCL033C 0.159255283 0.206465237 0.118093087 "YCL033C -- unknown -- similarity to Neisseria pilin B, putative transcription regulator" YOL111C YOL111C 1.5 24 2.4 0.5488 0.38332507 iYOL111C 0.491089484 0.157142857 0.12244898 YOL111C -- unknown -- similarity to human ubiquitin-like protein GDX YJR049C UTR1 1.3 21 2.4 0.5488 0.461501118 iYJR049C 0.450950999 0.841819633 0.241260974 UTR1 -- unknown -- may be associated with ferric reductase activity YOR357C GRD19 1.3 21 2.4 0.5488 0.839693798 iYOR357C 0.453573438 0.963744763 0.28158234 GRD19 -- secretion -- retrieval of late Golgi membrane proteins from the prevacuolar compartment YHR030C SLT2 1.2 19 2.4 0.5488 0.521386976 iYHR030C 0.4969882 0.632424878 0.504484489 "SLT2 -- signaling, PKC1 pathway -- Serine/threonine protein kinase of MAP kinase family involved in the cell wall integrity (low-osmolarity) pathway" YMR183C SSO2 1.2 19 2.4 0.5488 0.335332738 iYMR183C 0.417494197 0.672146848 0.428375765 SSO2 -- secretion -- Syntaxin homolog (t-SNARE) involved in vesicle transport from Golgi to plasma membrane YNL081C YNL081C 1.2 18 2.4 0.5488 0.307789174 iYNL081C 0.2532203 0.680555556 0.117575122 "YNL081C -- unknown -- Putative mitochondrial ribosomal small subunit, has similarity to ribosomal protein S13 of prokaryotes and plant mitochondria" YBR253W SRB6 1.1 17 2.4 0.5488 0.378493959 iYBR252W 0.344155121 0.279825764 0.676362683 SRB6 -- transcription -- Component of RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex YDR354W TRP4 1.1 17 2.4 0.5488 0.548212386 iYDR353W 0.65260896 0.943632229 0.570716458 "TRP4 -- tryptophan biosynthesis -- Anthranilate phosphoribosyltransferase, second step in tryptophan biosynthesis pathway" YHR108W GGA2 1.1 17 2.4 0.5488 0.127339185 iYHR107C 0.128650586 0.521833709 0.221978558 GGA2 -- unknown -- trafficking of proteins between the trans-Golgi network and the vacuole YLL029W YLL029W 1.1 17 2.4 0.5488 0.465134738 iYLL030C 0.292979564 0.448462614 0.412672241 YLL029W -- unknown -- similarity to X-prolyl aminopeptidase P YNL097C PHO23 1.1 17 2.4 0.5488 0.023925931 iYNL097C tL(CAA)N 0.122045943 0.588682359 0.026559454 0.070023862 0.261998871 "PHO23 -- phosphate signaling -- chromatin remodeling and possibly transcription regulation, involved in expression of PHO5" YBL083C YBL083C 1 15.5 2.4 0.5488 0.596045184 0.553843672 YBL083C -- unknown -- unknown functionquestionable ORF YBR257W POP4 1 15 2.4 0.5488 0.109446448 iYBR256C 0.395114573 0.438574837 0.768616802 "POP4 -- rRNA and tRNA processing -- component of both RNase MRP and RNase P, involved in both rRNA and tRNA processing" YDR153C YDR153C 1 15 2.4 0.5488 iYDR153C 0.631236182 0.371348763 YDR153C -- unknown -- unknown function YDR459C YDR459C 1 15 2.4 0.5488 0.52228556 iYDR459C 0.545021341 0.748619233 0.621843995 "YDR459C -- unknown -- unknown function, has similarity to Erf2p" YDR494W YDR494W 1 16 2.4 0.5488 0.299949852 iYDR493W 0.279740461 0.331708902 0.131091618 YDR494W -- unknown -- unknown function YGR261C APL6 1 16 2.4 0.5488 0.420929285 iYGR261C 0.195560994 0.519393456 0.265615748 "APL6 -- vacuolar protein targeting -- Beta-adaptin, large subunit of clathrin-associated protein (AP) complex" YHR205W SCH9 1 15 2.4 0.5488 0.637806889 iYHR204W 0.571106859 "SCH9 -- signaling -- Serine/threonine protein kinase involved in nutrient-sensing signaling pathway, probably parallel to cAMP pathway" YJL030W MAD2 1 15 2.4 0.5488 0.825440335 iYJL031C 0.297070863 0.508279824 0.298268778 MAD2 -- mitosis -- Spindle-assembly checkpoint protein YJL126W NIT2 1 15 2.4 0.5488 0.064153067 iYJL127C 0.128573192 0.329342967 0.259417601 NIT2 -- unknown -- Nitrilase YLR158C ASP3C 1 15 2.4 0.5488 0.40835159 iYLR158C-0 iYLR158C-1 0.108462854 0.156847204 0.746067597 0.329759584 0.185838368 "ASP3C -- asparagine utilization -- L-asparaginase II, extracellular" YML079W YML079W 1 16 2.4 0.5488 0.186747164 iYML080W 0.643611439 0.564222078 0.705089941 YML079W -- unknown -- unknown function YNL262W POL2 1 15 2.4 0.5488 0.881534256 iYNL263C 0.16353584 0.450129955 0.669052909 "POL2 -- DNA replication -- DNA polymerase epsilon large subunit, catalytic subunit essential for DNA replication and involved in DNA repair" YOL070C YOL070C 1 15 2.4 0.5488 0.145915314 iYOL070C 0.545533763 0.495433226 0.321947326 YOL070C -- unknown -- unknown function YAL019W YAL019W 0.9 15 2.4 0.5488 0.545063208 iYAL020C 0.085744049 0.363872645 0.09901708 "YAL019W -- unknown -- Snf2p family with a DNA-dependent ATPase domain, involved in resistance to UV radiation" YEL006W YEL006W 0.9 13 2.4 0.5488 0.630116735 iYEL007W 0.375427965 0.690220923 0.246511253 YEL006W -- unknown -- Member of mitochondrial carrier (MCF) family of membrane transporters YFL027C YFL027C 0.9 14 2.4 0.5488 0.468619157 iYFL027C 0.458348397 0.817215287 0.563482268 YFL027C -- unknown -- unknown function YGL112C TAF60 0.9 15 2.4 0.5488 0.634122196 iYGL112C 0.161083016 0.85945857 0.154769578 TAF60 -- transcription -- Component of TAF(II) complex (TBP-associated protein complex) and SAGA complex (Spt-Ada-Gcn5-acetyltransferase)required for activated transcription by RNA polymerase II YIL059C YIL059C 0.9 14 2.4 0.5488 0.477027493 0.61867518 YIL059C -- unknown -- unknown function YML046W PRP39 0.9 13 2.4 0.5488 0.690425382 iYML047C 0.389429252 0.780995402 0.327516299 PRP39 -- mRNA splicing -- U1 snRNA-associated commitment of pre-mRNA to splicing pathway YOR174W MED4 0.9 14 2.4 0.5488 0.351134986 iYOR173W 0.571107002 0.452384789 0.743273934 MED4 -- transcription -- Component of RNA polymerase II holoenzyme and mediator subcomplex YOR189W YOR189W 0.9 13 2.4 0.5488 0.172142076 iYOR188W 0.332041884 0.31292897 0.431086974 YOR189W -- unknown -- unknown function YPL122C TFB2 0.9 14 2.4 0.5488 0.388677525 iYPL122C 0.291304701 0.421871143 0.492039587 "TFB2 -- transcription -- Component of RNA polymerase II transcription initiation TFIIH (factor b), 55 kDa subunit" YDR036C YDR036C 0.8 12 2.4 0.5488 0.896273771 iYDR036C 0.98692732 0.553577183 0.255800726 YDR036C -- unknown -- Member of enoyl-coA hydratase/isomerase protein family YEL059C-A SOM1 0.8 12 2.4 0.5488 0.122002642 0.06091585 "SOM1 -- protein processing -- Possible subunit of Imp peptidase complex, required for mitochondrial inner peptidase function" YGR263C YGR263C 0.8 12 2.4 0.5488 0.530632734 iYGR263C 0.342622622 0.87565842 0.555811435 YGR263C -- unknown -- unknown function YJR074W MOG1 0.8 12 2.4 0.5488 0.829367047 iYJR073C 0.719523941 0.780766161 0.45754717 "MOG1 -- unknown -- nuclear import, interacts with Gsp1p" YLR436C ECM30 0.8 12 2.4 0.5488 0.456117561 iYLR436C 0.743092539 0.405172414 0.12803423 ECM30 -- cell wall biogenesis -- Protein possibly involved in cell wall structure or biosynthesis YML011C YML011C 0.8 13 2.4 0.5488 0.334536568 iYML011C 0.277242432 0.734289397 0.166666667 YML011C -- unknown -- unknown function YNL024C YNL024C 0.8 13 2.4 0.5488 0.824965587 iYNL024C 0.82707865 0.41268681 0.329600387 YNL024C -- unknown -- unknown function YNL080C YNL080C 0.8 13 2.4 0.5488 0.734155505 iYNL080C 0.50237491 0.66745283 0.537562742 YNL080C -- unknown -- unknown function YNL289W PCL1 0.8 12 2.4 0.5488 0.610902373 iYNL290W 0.289213295 0.580974843 0.21867518 PCL1 -- cell cycle -- G1/S-specific cyclin that can interact with the Cdc28p-like kinase Pho85p YPL038W MET31 0.8 13 2.4 0.5488 0.226756706 iYPL039W 0.279320484 0.075129955 0.21093813 "MET31 -- sulfur amino acid metbolism -- Zinc-finger transcriptional regulation of methionine metabolism, has two tandem C2H2-type zinc fingers" YIL014W MNT3 0.7 11 2.4 0.5488 0.57406508 iYIL015C-A itT(AGU)I2 0.682531813 0.756333031 0.903151485 0.737589785 0.590103751 MNT3 -- protein glycosylation -- Mannosyltransferase that adds the final mannose to O-linked oligosaccharide chainssimilar to Mnn1p YLR143W YLR143W 0.7 11 2.4 0.5488 0.541412392 iYLR142W itD(GUC)L1 0.662438273 0.524143618 0.796052632 0.585625555 0.186802974 YLR143W -- unknown -- weak similarity to Mmd1p YMR076C PDS5 0.7 10 2.4 0.5488 0.171404333 iYMR076C itV(AAC)M2 0.460522452 0.711653475 0.324650089 0.410250162 0.440604934 "PDS5 -- mitosis, sister chromatid cohesion -- unknown functionloss can lead to precocious separation of sister chromatids" YMR138W CIN4 0.7 10 2.4 0.5488 0.518771605 iYMR137C 0.396282689 0.548916841 0.162930474 "CIN4 -- mitosis, chromosome segregation -- GTP-binding chromosome segregation, mutants arrest at mitosis with loss of microtubule structure" YOR233W KIN4 0.7 10 2.4 0.5488 0.33171352 iYOR232W 0.430118461 0.482758621 0.393087335 "KIN4 -- unknown -- Serine/threonine protein kinase related to Kin1p and Kin2p, catalytic domain is highly related to Snf1p" YJL081C ARP4 0.6 10 2.4 0.5488 0.088362621 iYJL081C 0.031676537 0.425797615 0.008579058 "ARP4 -- cytoskeleton -- interacts with core histones, member of NuA4 histone acetyltransferase complex" YML096W YML096W 0.6 10 2.4 0.5488 0.372507303 iYML097C 0.556336564 0.865293432 0.583271623 YML096W -- unknown -- similarity to asparagine synthetases Asn1p and Asn2p YBL061C SKT5 1.5 23 2.3 0.5362 1 0.826273495 iYBL061C 0.97432819 0.54301676 0.851998066 "SKT5 -- cell wall biogenesis -- Protoplast regeneration and killer toxin resistance protein, required for chitin synthase III activity" YGR178C PBP1 2.1 34 2.3 0.5362 0.590311524 iYGR178C 0.19051136 0.557017544 0.078489355 PBP1 -- mRNA processing -- interacts with Poly(A)-binding protein Pab1p YFL048C EMP47 2 31 2.3 0.5362 0.700380102 iYFL048C 0.252454291 0.833306478 0.320885434 EMP47 -- secretion -- Golgi and endoplasmic reticulum membrane C-terminal dilysine (KKXX or KXKXX) motif YMR298W YMR298W 1.9 32 2.3 0.5362 0.411399131 iYMR297W 0.690653587 0.751956118 0.601301115 YMR298W -- unknown -- unknown function YDR504C YDR504C 1.8 29 2.3 0.5362 0.517485976 0.308088946 YDR504C -- unknown -- unknown function YJR065C ARP3 1.8 29 2.3 0.5362 0.699693994 iYJR065C 0.239807647 0.889376218 0.160202655 "ARP3 -- cytoskeleton -- Actin-related ARP2/3 complex, involved in cell polarity and endocytosis" YAL030W SNC1 1.6 24 2.3 0.5362 0.80071854 iYAL031C 0.382883171 0.803013213 0.284277733 SNC1 -- secretion -- Synaptobrevin (v-SNARE) homolog present on post-Golgi vesicles YGL244W RTF1 1.5 23 2.3 0.5362 0.178300499 iYGL245W 0.390362264 0.128581412 0.577908476 RTF1 -- transcription -- important for TATA site selection by the TATA binding Spt15p YBR236C ABD1 1.3 21 2.3 0.5362 0.44105609 iYBR236C 0.421316036 0.694253791 0.539106145 ABD1 -- mRNA capping -- mRNA cap methyltransferase that methylates the terminal guanine residue of mRNA cap YDR145W TAF61 1.3 22 2.3 0.5362 0.153577131 iYDR144C 0.510090063 0.18973574 0.633203379 TAF61 -- transcription -- Component of TAF(II) complex (TBP-associated protein complex)and SAGA complex (Spt-Ada-Gcn5-acetyltransferase)required for activated transcription by RNA polymerase II YER183C YER183C 1.3 21 2.3 0.5362 0.789294684 iYER183C-0 iYER183C-1 0.217927318 0.168899401 0.431437319 0.12226656 0.362159329 YER183C -- unknown -- unknown function YLL064C YLL064C 1.3 22 2.3 0.5362 0.921115604 iYLL064C 0.941072489 0.468567251 0.555747552 YLL064C -- unknown -- Member of seripauperin (PAU) family (YLL064C and PAU6 code for identical proteins) YML129C COX14 1.3 22 2.3 0.5362 0.260647583 iYML129C 0.71632873 0.506574171 0.871071308 COX14 -- respiration -- assembly of cytochrome oxidase YPL265W DIP5 1.3 23 2.3 0.5362 0.587878327 iYPL266W 0.216831066 0.682300667 0.569771189 DIP5 -- transport -- Dicarboxylic amino acid permease YHR024C MAS2 1.2 20 2.3 0.5362 0.307495771 iYHR024C 0.509788834 0.564634247 0.389622946 MAS2 -- protein processing -- Catalytic (alpha) subunit of mitochondrial processing peptidase YKL012W PRP40 1.2 21 2.3 0.5362 0.572232776 iYKL013C 0.22366874 0.727392413 0.182681564 PRP40 -- mRNA splicing -- U1 snRNA-associated pre-mRNA splicing YLR275W SMD2 1.2 21 2.3 0.5362 0.500040196 iYLR274W 0.137311991 0.601274502 0.267462638 "SMD2 -- mRNA splicing -- Spliceosomal snRNA-associated Sm core protein, also likely associated with telomerase TLC1 RNA" YPR073C LTP1 1.2 20 2.3 0.5362 0.37368809 iYPR073C 0.66514211 0.449002394 0.774009024 LTP1 -- unknown -- Protein tyrosine phosphatase (PTPase) with similarity to a phosphatase from bovine heart and human placenta YDL099W YDL099W 1.1 18 2.3 0.5362 0.066456209 iYDL100C 0.119276172 0.055865922 0.140788283 YDL099W -- unknown -- unknown function YDL230W PTP1 1.1 19 2.3 0.5362 0.80586612 iYDL231C 0.334223353 0.59917722 0.305347167 PTP1 -- unknown -- Protein tyrosine phosphatase YGL002W ERP6 1.1 19 2.3 0.5362 0.288871404 iYGL003C 0.35550903 0.525157233 0.372428813 ERP6 -- membrane trafficking; secretion (putative) -- similarity to COPII-coated vesicle proteins Emp24p and Erv25p YGL082W YGL082W 1.1 18 2.3 0.5362 0.499502432 iYGL083W 0.231814896 0.912185886 0.026496409 YGL082W -- unknown -- unknown function YHR056C YHR056C 1.1 17 2.3 0.5362 0.462489569 iYHR056C 0.260676639 0.646998404 0.425573932 "YHR056C -- unknown -- unknown function, encoded from the CUP1A and CUP1B repeat region" YHR195W NVJ1 1.1 18 2.3 0.5362 0.401813765 iYHR194W 0.467159197 0.519952115 0.156892797 NVJ1 -- vacuolar protein targeting (putative) -- Vac8p-binding protein YMR214W SCJ1 1.1 19 2.3 0.5362 0.262577589 iYMR213W 0.620173113 0.348034438 0.196019981 "SCJ1 -- unknown -- Homolog of E. coli DnaJ, functions in the endoplasmic reticulum by interaction with Kar2p" YNL320W YNL320W 1.1 18 2.3 0.5362 0.444490678 iYNL321W 0.472065631 0.862068966 0.216654324 YNL320W -- unknown -- similarity to S. pombe bem1/bud5 suppressor YBL055C YBL055C 1 16 2.3 0.5362 0.793156482 iYBL055C 0.628223746 0.975803634 0.78754988 YBL055C -- unknown -- unknown function YBR066C NRG2 1 16 2.3 0.5362 0.335314857 iYBR066C 0.41741522 0.357864919 0.54795515 "NRG2 -- unknown -- Suppressor of snf mutations, predicted transcription factor with two tandem C2H2-type zinc fingers" YBR139W YBR139W 1 16 2.3 0.5362 0.376522044 iYBR138C 0.703276186 0.901588085 0.661053472 YBR139W -- unknown -- similarity to serine-type carboxypeptidases YDL093W PMT5 1 15 2.3 0.5362 0.645676096 0.465408805 "PMT5 -- protein glycosylation -- similarity to O-mannosyltransferases Pmt1p, Pmt2p, Pmt3p, Pmt4p, and Pmt6p" YGL079W YGL079W 1 15 2.3 0.5362 0.851060385 iYGL080W 0.498645153 0.638148444 YGL079W -- unknown -- unknown function YGR119C NUP57 1 16 2.3 0.5362 0.687957726 iYGR119C 0.557083688 0.903563941 0.403671215 "NUP57 -- nuclear protein targeting -- Nuclear pore protein (nucleoporin) of GLFG family, acts in a complex with Nic96p, Nup49p, and Nsp1p" YHR175W CTR2 1 17 2.3 0.5362 0.784692574 iYHR174W 0.910703277 0.897227022 0.4437357 CTR2 -- transport -- Putative low-affinity copper transport protein YMR212C EFR3 1 17 2.3 0.5362 0.608101707 iYMR212C 0.209125343 0.869070825 0.431266903 "EFR3 -- unknown -- similarity to Drosophila cmp44E, conserved, ubiquitous membrane protein requiired for cell viability" YAR007C RFA1 0.9 15 2.3 0.5362 0.639948249 iYAR007C 0.087857507 0.690380277 0.155360168 "RFA1 -- DNA replication -- DNA replication factor A, 69K subunit, binds single-stranded DNA" YDR094W 0.9 14 2.3 0.5362 0.250691936 0.254139912 YDR266C YDR266C 0.9 14 2.3 0.5362 0.716631261 iYDR266C 0.518647141 0.864163713 0.61688472 "YDR266C -- unknown -- unknown function, contains a RING finger domain" YDR514C YDR514C 0.9 15 2.3 0.5362 0.332412434 iYDR514C 0.540930352 0.654524808 0.684676776 YDR514C -- unknown -- unknown function YGR174C CBP4 0.9 14 2.3 0.5362 0.18084622 iYGR174C 0.559072104 0.200957702 0.560273184 CBP4 -- respiration -- Ubiquinol-cytochrome c reductase assembly factoressential for assembly and stability of ubiquinol-cytochrome c reductase YGR193C PDX1 0.9 16 2.3 0.5362 0.724286245 iYGR193C 0.186688364 0.734371219 0.143784001 PDX1 -- glycolysis -- Pyruvate dehydrogenase complex protein Xbinding protein for Lpd1p YGR241C YAP1802 0.9 14 2.3 0.5362 0.23241822 0.228651237 YAP1802 -- endocytosis and secretion -- homologous to clathrin assembly polypeptide AP180interacts with Pan1p YHR110W ERP5 0.9 15 2.3 0.5362 0.342476179 iYHR109W 0.407121841 0.919952115 0.456723401 ERP5 -- membrane trafficking; secretion (putative) -- similarity to COPII-coated vesicle proteins Emp24p and Erv25p YIL115C NUP159 0.9 15 2.3 0.5362 0.585443575 iYIL115C 0.575383616 0.793291098 0.701026277 NUP159 -- nuclear protein targeting -- Nuclear pore protein (nucleoporin) with XFXFG repeats YDR208W MSS4 0.8 13 2.3 0.5362 0.450422586 iYDR207C 0.26210841 0.4647291 0.223483913 MSS4 -- actin organization -- Phosphatidylinositol-4-phosphate 5-kinaserequired for proper organization of actin cytoskeleton YDR257C RMS1 0.8 13 2.3 0.5362 0.86532179 iYDR257C 0.695380369 0.907594833 0.791585445 RMS1 -- transcription -- Putative transcriptional regulator YDR478W SNM1 0.8 12 2.3 0.5362 0.178018637 iYDR477W 0.559340321 0.27773344 0.602402699 SNM1 -- rRNA processing -- RNA-binding RNase MRP YGL039W YGL039W 0.8 14 2.3 0.5362 0.805474794 iYGL040C-0 iYGL040C-1 0.361018348 0.619067798 0.895150389 0.404044473 0.673630717 YGL039W -- unknown -- unknown function YHL026C YHL026C 0.8 13 2.3 0.5362 0.493867768 iYHL026C 0.100743248 0.875926523 0.015634 "YHL026C -- unknown -- unknown function, has potential signal sequence and 2 potential transmembrane domains" YHR131C YHR131C 0.8 12 2.3 0.5362 0.163968278 iYHR131C 0.385485722 0.481743536 0.599015891 YHR131C -- unknown -- unknown function YMR221C YMR221C 0.8 13 2.3 0.5362 0.404656185 iYMR221C 0.570059881 0.618834796 0.793425717 YMR221C -- unknown -- unknown function YOR163W DDP1 0.8 13 2.3 0.5362 0.396782958 iYOR162C 0.239211156 0.355425601 0.301240735 DDP1 -- unknown -- Diadenosine hexaphosphate (Ap6A) hydrolase YOR319W HSH49 0.8 12 2.3 0.5362 0.586294466 iYOR318C 0.388225874 0.832782125 0.133580705 "HSH49 -- mRNA splicing -- U2 snRNP protein and pre-mRNA splicing factor with similarity to human SAP49, has 2 RNA recognition (RRM) domains" YDR176W NGG1 0.7 11 2.3 0.5362 0.396947931 iYDR175C 0.178403756 0.746942697 0.217048018 NGG1 -- chromatin structure -- Component of two nucleosomal histone acetyltransferase complexes YDR493W YDR493W 0.7 11 2.3 0.5362 0.342257478 iYDR492W 0.516679627 0.697181451 0.433209797 YDR493W -- unknown -- unknown function YGR031W YGR031W 0.7 11 2.3 0.5362 0.816494618 iYGR030C 0.712805569 0.930726257 0.716617934 YGR031W -- unknown -- unknown function YLR287C YLR287C 0.7 12 2.3 0.5362 0.977085798 iYLR287C 0.941144248 0.948801292 0.864724661 YLR287C -- unknown -- unknown function YLR364W YLR364W 0.7 11 2.3 0.5362 0.179256684 iYLR363C 0.320005267 0.204333439 0.364766082 YLR364W -- unknown -- weak similarity to yeast glutaredoxin-like protein YMR062C ARG7 0.7 11 2.3 0.5362 0.486974539 iYMR062C 0.336338519 0.825310623 0.609813084 "ARG7 -- arginine biosynthesis -- Ornithine acetyltransferasecatalyzes the fifth step in ornithine and arginine biosynthesis, also has acetylglutamate synthase activity" YMR277W FCP1 0.7 10 2.3 0.5362 0.138134258 iYMR276W 0.265710167 0.496502921 0.144147778 FCP1 -- transcription -- TFIIF-interacting component of C-terminal domain phosphatase YOL054W YOL054W 0.7 10 2.3 0.5362 0.154025534 iYOL055C YOLWdelta6 0.540391776 0.723782812 0.138097927 0.294324023 0.532707973 "YOL054W -- unknown -- normal resistance to NaCl and for normal mating efficiency of MATa cells, contains a C3HC4-type zinc finger" YOL140W ARG8 0.7 10 2.3 0.5362 0.751143417 iYOL141W 0.20130074 0.969223489 0.370532814 ARG8 -- arginine biosynthesis -- Acetylornithine aminotransferasecatalyzes the fourth step in ornithine and arginine biosynthesis YOR130C ORT1 0.6 10 2.3 0.5362 0.104523002 iYOR130C tD(GUC)O 0.465289748 0.633413262 0.359170575 0.632337526 0.373982442 "ORT1 -- arginine biosynthesis -- Ornithine transport mitochondria involved in arginine metabolism, member of mitochondrial carrier (MCF) family" YOR287C YOR287C 0.6 9 2.3 0.5362 0.052764613 iYOR287C 0.343207603 0.01500399 0.398322851 "YOR287C -- unknown -- unknown function, possible coiled-coil protein" YPL157W YPL157W 0.6 10 2.3 0.5362 0.332378804 iYPL158C 0.67321588 0.244533121 0.529236668 YPL157W -- unknown -- Putative methyltransferase unknown role YEL022W GEA2 0.9 16 2.2 0.5247 1 0.711407145 iYEL023C 0.986360315 0.150050693 0.809018356 GEA2 -- secretion -- Component of complex with guanine-nucleotide-exchange activity for ARF YEL060C PRB1 1.5 25 2.2 0.5247 0.39913427 iYEL060C 0.338104479 0.410790549 0.167278532 "PRB1 -- protein degradation -- Protease B (yscB/PrB/cerevisin), serine protease of subtilisin family with broad proteolytic specificity" YMR188C YMR188C 1.5 24 2.2 0.5247 0.432758745 iYMR188C 0.142510098 0.576998051 0.229938272 "YMR188C -- unknown -- Possible mitochondrial ribosomal protein, has weak similarity to prokaryotic 30S ribosomal protein S17" YGR275W RTT102 1.3 23 2.2 0.5247 0.037017622 iYGR274C 0.54591963 0.156809733 0.398868137 RTT102 -- transposition (putative) -- Regulator of Ty1 Transposition YLL027W ISA1 1.3 22 2.2 0.5247 0.329977721 iYLL028W 0.373122818 0.444095038 0.27497583 ISA1 -- unknown -- Mitochondrial normal iron metabolism YML119W YML119W 1.3 22 2.2 0.5247 0.372885552 iYML120C 0.306104818 0.631497726 0.756767876 YML119W -- unknown -- unknown function YDR068W DOS2 1.2 22 2.2 0.5247 0.081096747 iYDR067C 0.365215859 0.031237274 0.519933911 DOS2 -- unknown -- unknown function YER134C YER134C 1.2 21 2.2 0.5247 0.565255699 iYER134C 0.177474681 0.639063592 0.157823589 YER134C -- unknown -- unknown function YGR057C LST7 1.2 20 2.2 0.5247 0.355170265 iYGR057C 0.257155289 0.755745184 0.242491566 LST7 -- secretion -- regulated transport of nitrogen-regulated permeases from the Golgi to the plasma membrane YJR042W NUP85 1.2 20 2.2 0.5247 0.424585906 iYJR041C 0.11837298 0.324074074 0.284805027 NUP85 -- nuclear protein targeting -- Nuclear pore protein YKL184W SPE1 1.2 21 2.2 0.5247 0.681398773 iYKL185W 0.628142275 0.840321454 0.615211086 "SPE1 -- polyamine biosynthesis -- Ornithine decarboxylase, rate limiting step of polyamine biosynthesis pathway" YLL043W FPS1 1.2 21 2.2 0.5247 0.431655629 iYLL044W 0.97889893 0.29171995 0.503054839 "FPS1 -- transport -- Glycerol channel protein, member of major intrinsic protein (MIP) family of transmembrane channel proteins" YMR311C GLC8 1.2 21 2.2 0.5247 0.118953616 iYMR311C 0.378471088 0.389863548 0.386480825 "GLC8 -- mitosis, chromosome segregation -- Modulator of protein serine/threonine phosphatase Glc7p, involved in control of vacuole fusion" YOR244W ESA1 1.2 21 2.2 0.5247 0.255861542 iYOR243C 0.430019062 0.748922586 0.498515024 "ESA1 -- chromatin structure -- Histone acetyltransferase of MYST family, catalytic subunit of NuA4 histone acetylase complex" YGL062W PYC1 1.1 19 2.2 0.5247 0.510913631 iYGL063W 0.470590661 0.722346369 0.419820885 "PYC1 -- TCA cycle -- Pyruvate carboxylase 1, catalyzes convertion of pyruvate to oxaloacetate in the gluconeogenesis pathway" YHR106W TRR2 1.1 18 2.2 0.5247 0.110394377 iYHR105W 0.4679429 0.396169194 0.242481641 "TRR2 -- pyrimidine biosynthesis -- Mitochondrial thioredoxin reductase, has strong similarity to cytoplasmic thioredoxin reductase Trr1p" YLR330W CHS5 1.1 18 2.2 0.5247 0.55481951 iYLR329W 0.636862662 0.496293909 0.744643999 CHS5 -- cell wall biogenesis -- chitin synthase III activity YPR115W YPR115W 1.1 19 2.2 0.5247 0.451655084 iYPR114W 0.287164082 0.2445753 0.113872645 YPR115W -- unknown -- unknown function YDR090C YDR090C 1 18 2.2 0.5247 0.232227985 iYDR090C 0.178975163 0.1989204 0.311582809 YDR090C -- unknown -- similarity to Yro2p YDR175C YDR175C 1 17 2.2 0.5247 0.622173581 iYDR175C 0.178403756 0.944373504 0.217048018 YDR175C -- unknown -- unknown function YER092W YER092W 1 17 2.2 0.5247 0.856233244 YER091C-A iYER091C-A 0.28527004 0.121509865 0.189870032 0.125120851 0.119234801 YER092W -- unknown -- unknown function YGL044C RNA15 1 18 2.2 0.5247 0.377210378 iYGL044C 0.031433759 0.43066871 0.060183693 "RNA15 -- mRNA 3'-end processing -- Component of pre-mRNA cleavage and polyadenylation factor I (CFI), involved in poly(A) site choice, interacts with Rna14p, Pap1p, and Pcf11p, contains one RNA recognition (RRM) domain" YJL101C GSH1 1 17 2.2 0.5247 0.537768133 iYJL101C 0.271819437 0.742346117 0.381543922 "GSH1 -- glutathione biosynthesis -- Gamma-glutamylcysteine synthetase, catalyzes rate-limiting step in glutathione synthesis" YKL179C YKL179C 1 17 2.2 0.5247 0.711797419 iYKL179C 0.551364521 0.571588188 0.65911306 YKL179C -- unknown -- similarity to kinesin and human kinesin-related protein CENP-E YNL166C BNI5 1 16 2.2 0.5247 0.424847607 iYNL166C 0.892326866 0.344034847 0.550596197 BNI5 -- unknown -- can suppress some cdc3 cdc10 double mutant strains YPL011C TAF47 1 17 2.2 0.5247 0.356396212 iYPL011C 0.517983275 0.550682261 0.443832984 TAF47 -- transcription -- Component of TAF(II) complex YPR129W SCD6 1 17 2.2 0.5247 0.570796726 iYPR128C 0.120319174 0.031862547 0.025672673 SCD6 -- secretion (putative) -- Multicopy suppressor of inviable strains of clathrin heavy chain deficient yeast YBR175W YBR175W 0.9 14 2.2 0.5247 0.5643616 0.913608131 "YBR175W -- unknown -- unknown function, has several WD (WD-40) repeats" YGL100W SEH1 0.9 15 2.2 0.5247 0.382461292 iYGL101W 0.326621742 0.788511118 0.594173982 "SEH1 -- nuclear protein targeting -- found in complex with nuclear pore proteins, member of WD (WD-40) repeat family" YGL127C SOH1 0.9 14 2.2 0.5247 0.127054093 iYGL127C 0.459000327 0.244988473 0.198759265 SOH1 -- unknown -- allows hpr1 null mutant to grow at 37 deg YJL065C YJL065C 0.9 15 2.2 0.5247 0.399315452 0.638341651 YJL065C -- unknown -- similarity to DNA polymerase epsilon subunit c YNL045W YNL045W 0.9 16 2.2 0.5247 0.387705348 iYNL046W 0.41628892 0.734693878 0.163991288 YNL045W -- unknown -- Bifunctional leukotriene A4 hydrolase and anion-activated leucyl aminopeptidase YOR026W BUB3 0.9 15 2.2 0.5247 0.403620189 iYOR025W 0.117470349 0.531693918 0.052114924 "BUB3 -- cell cycle, checkpoint -- Checkpoint cell cycle arrest in response to loss of microtubule function" YOR203W YOR203W 0.9 16 2.2 0.5247 0.636555328 0.849749033 YOR203W -- unknown -- unknown function YGL092W NUP145 0.8 13 2.2 0.5247 0.575403079 iYGL093W 0.475942841 0.649002394 0.268356075 "NUP145 -- nuclear protein targeting -- Nuclear pore protein (nucleoporin) with GLFG repeat motif, required for nuclear envelope structure" YGR252W GCN5 0.8 14 2.2 0.5247 0.352602095 iYGR251W 0.311759017 0.227958377 0.273822825 GCN5 -- chromatin structure -- Component of two nucleosomal histone acetyltransferase complexes YHR046C YHR046C 0.8 14 2.2 0.5247 0.239583328 iYHR046C 0.158778479 0.44385448 0.393304425 "YHR046C -- unknown -- similarity to inositol monophosphatase of E. coli, Aspergillus nidulans, and Neurospora crassa" YIL009W FAA3 0.8 13 2.2 0.5247 0.603103143 iYIL009C-A itD(GUC)I2 0.592555583 0.759562329 0.474740091 0.629229778 0.919792498 FAA3 -- fatty acid metabolism -- Acyl-CoA synthase (long-chain fatty acid CoA ligase)activates endogenous but not imported fatty acids YLR114C EFR4 0.8 12 2.2 0.5247 0.090166278 iYLR114C 0.404842951 0.201678598 0.586975362 EFR4 -- unknown -- weak similarity in the C-terminus to Drosophila melanogaster bicaudal-D protein YNL023C FAP1 0.8 12 2.2 0.5247 0.477173385 iYNL023C 0.453715613 0.664852458 0.349339349 FAP1 -- transcription (putative) -- similarity to human DNA-binding protein tenascin and Drosophila melanogaster shuttle craft protein YNR026C SEC12 0.8 12 2.2 0.5247 0.384154381 iYNR026C 0.23286995 0.778294225 0.215782359 "SEC12 -- secretion -- Guanine-nucleotide exchange factor for Sar1p, required for vesicle formation but is not incorporated into the vesicle" YOR143C THI80 0.8 13 2.2 0.5247 0.676478924 iYOR143C 0.273921966 0.943131403 0.175019952 "THI80 -- thiamine metabolism -- Thiamine pyrophosphokinase, converts thiamine to the coenzyme thiamine pyrophosphate" YPL115C BEM3 0.8 14 2.2 0.5247 0.405155021 iYPL115C 0.248894734 0.303403878 0.235540857 "BEM3 -- bud emergence -- GTPase-activating protein (GAP) for Cdc42p and Rho1p, contains a PH (pleckstrin) domain" YPL139C UME1 0.8 14 2.2 0.5247 0.334351575 iYPL139C 0.572576877 0.810774142 0.66634178 UME1 -- meiosis -- Negative regulator of meiosis YPR190C RPC82 0.8 13 2.2 0.5247 0.109600053 iYPR190C 0.513001277 0.108203736 0.344359417 "RPC82 -- transcription -- RNA polymerase III, third-largest subunit" YBL052C SAS3 0.7 12 2.2 0.5247 0.241667101 iYBL052C 0.19196047 0.333709314 0.080601555 "SAS3 -- silencing -- histone acetyltransferase activity, influences silencing at HMR locus, has a single C2H2-type zinc finger -36308" YDR527W YDR527W 0.7 11 2.2 0.5247 0.54006355 0.522693338 YDR527W -- unknown -- unknown function YGR014W MSB2 0.7 11 2.2 0.5247 0.489033939 iYGR013W 0.2884534 0.749516597 0.205929745 MSB2 -- bud emergence -- for which overproduction suppresses bud emergence defect of cdc24 mutant YJL210W PEX2 0.7 12 2.2 0.5247 0.203851786 0.389132554 PEX2 -- peroxisome biogenesis -- Peroxisomal biogenesis protein (peroxin) required for peroxisomal import of some proteins YKR079C YKR079C 0.7 12 2.2 0.5247 0.375741344 iYKR079C 0.588401422 0.644532214 0.828391879 YKR079C -- unknown -- unknown function YLR316C TAD3 0.7 12 2.2 0.5247 0.281501678 0.594659998 TAD3 -- tRNA processing -- Subunit of tRNA-specific adenosine-34 deaminase YML060W OGG1 0.7 11 2.2 0.5247 0.444044503 iYML061C 0.772122532 0.793724525 0.77956816 "OGG1 -- DNA repair -- DNA glycosylase, excises 7,8-dihydro-8-oxoguanine (8-OxoG) and formamidopyrimidine (Fapy) residues from DNA" YNL256W FOL1 0.7 12 2.2 0.5247 0.473045168 iYNL257C 0.471601746 0.923021478 0.376058724 "FOL1 -- folate biosynthesis -- Dihydroneopterin aldolase, dihydro-6-hydroxymethylpterin pyrophosphokinase, dihydropteroate synthetase" YOR321W PMT3 0.7 11 2.2 0.5247 0.159955779 iYOR320C 0.453284537 0.284031839 0.372903564 PMT3 -- protein glycosylation -- Mannosyltransferase (dolichyl phosphate-D-mannose YPL132W COX11 0.7 12 2.2 0.5247 0.964298001 iYPL133C 0.840626776 0.921896466 0.712992677 COX11 -- respiration -- heme A synthesis YPR128C YPR128C 0.7 12 2.2 0.5247 0.395063733 iYPR128C 0.120319174 0.729857633 0.025672673 "YPR128C -- unknown -- similarity to ADP/ATP carrier proteins, member of mitochondrial carrier family (MCF)localized to peroxisomes" YGL204C YGL204C 0.6 10 2.2 0.5247 0.702813607 iYGL204C 0.345265495 0.881890808 0.32316661 YGL204C -- unknown -- unknown function YMR070W MOT3 0.6 10 2.2 0.5247 0.133418925 iYMR069W 0.659126286 0.538661468 0.607257467 "MOT3 -- mating -- High-copy suppressor of MOT1-SPT3 synthetic lethality, has two tandem C2H2-type zinc fingers" YIR016W YIR016W 1.2 22 2.1 0.5121 1 0.911587768 iYIR015W 0.954281725 0.806865828 0.127853513 YIR016W -- unknown -- unknown function YGL084C GUP1 0.9 16 2.1 0.5121 1 0.902071485 iYGL084C 0.945305622 0.923243921 0.532003192 "GUP1 -- unknown -- unknown function, putative glycerol transporter with similarity to Gup2p" YBL021C HAP3 0.7 12 2.1 0.5121 1 0.987050693 iYBL021C 0.951460901 0.928687459 0.56473133 "HAP3 -- transcription -- Component (with Hap2p, Hap4p, and Hap5p) of heterotrimeric CCAAT-binding factor" YGR294W YGR294W 3.1 55 2.1 0.5121 0.92203405 0.607384251 YGR294W -- unknown -- Member of seripauperin (PAU) family YCL009C ILV6 2.9 50 2.1 0.5121 0.496001518 iYCL009C 0.6774126 0.761067928 0.331773816 ILV6 -- isoleucine and valine biosynthesis -- Acetolactate synthase regulatory subunit YNL305C YNL305C 2 35 2.1 0.5121 0.305221457 iYNL305C 0.063767623 0.528758331 0.070517568 YNL305C -- unknown -- similarity to Aspergillus nidulans negative-acting regulatory protein qutR and Drosophila melanogaster N-methyl-D-aspartate receptor-associated protein YJL171C YJL171C 1.7 29 2.1 0.5121 0.785427092 iYJL171C 0.462246852 0.954759584 0.266241022 YJL171C -- unknown -- unknown function YLR064W YLR064W 1.7 30 2.1 0.5121 0.363242942 iYLR063W 0.406359206 0.55581761 0.159831454 YLR064W -- unknown -- unknown function YLR146C SPE4 1.5 24 2.1 0.5121 0.383461562 iYLR146C 0.712932262 0.77325163 0.576318604 SPE4 -- spermine biosynthesis -- Spermine synthase (spermidine aminopropyltransferase) catalyzes the final step in of polyamine biosynthesis YOR131C YOR131C 1.5 26 2.1 0.5121 0.147719753 iYOR131C 0.233918894 0.502394254 0.170626843 YOR131C -- unknown -- similarity to E. coli protein yhfE of dam operon YOR142W LSC1 1.3 25 2.1 0.5121 0.502632442 iYOR141C 0.209208835 0.713407821 0.245899909 "LSC1 -- TCA cycle -- Alpha subunit of succinyl-CoA synthetase (succinyl-CoA ligase, succinate thiokinase)" YLR023C YLR023C 1.2 22 2.1 0.5121 0.474257328 iYLR023C 0.36159112 0.52690167 0.028810854 YLR023C -- unknown -- unknown function YLR387C YLR387C 1.2 22 2.1 0.5121 0.957092169 iYLR387C 0.976171593 0.706464485 0.731923384 "YLR387C -- unknown -- Protein possibly involved in proteasome function, has three dispersed C2H2-type zinc fingers" YMR302C RNA12 1.2 21 2.1 0.5121 0.53090189 iYMR302C 0.481771572 0.757541899 0.39516698 RNA12 -- rRNA processing -- role in early maturation of pre-rRNA and mitochondrial maintenance YPL031C PHO85 1.2 22 2.1 0.5121 0.255013396 iYPL031C 0.156765013 0.269980507 0.201926326 "PHO85 -- phosphate metabolism; cell cycle; glycogen metabolism -- Cyclin-dependent protein kinase that interacts with cyclin Pho80p to regulate phosphate pathway, also interacts with other Pho80p-like cyclins" YAL014C YAL014C 1.1 20 2.1 0.5121 0.331757773 iYAL014C 0.324781648 0.770750988 0.072530864 YAL014C -- unknown -- unknown functionhas potential C-terminal geranylgeranylation YBR172C SMY2 1.1 20 2.1 0.5121 0.413667795 iYBR172C 0.637492896 0.507075472 0.569735868 SMY2 -- unknown -- suppresses myo2-66 mutant when overexpressed YGR270W YTA7 1.1 20 2.1 0.5121 0.135395409 iYGR269W 0.272339565 0.5039085 0.105506823 YTA7 -- protein degradation -- Member of AAA ATPase protein family YKL140W TGL1 1.1 20 2.1 0.5121 0.266475058 iYKL141W 0.238688047 0.617283951 0.523755747 TGL1 -- glycerolipid metabolism -- Triglyceride lipase YLR347C KAP95 1.1 21 2.1 0.5121 0.838384076 iYLR347C 0.546786466 0.957846004 0.286751796 "KAP95 -- nuclear protein targeting -- Karyopherin-beta, targets proteins with nuclear localization (NLS) sequences to the nuclear pore complex" YMR061W RNA14 1.1 19 2.1 0.5121 0.192094087 iYMR060C 0.406373599 0.329577219 0.300439338 "RNA14 -- mRNA 3'-end processing -- Component of pre-mRNA cleavage and polyadenylation factor I (CFI) involved in poly(A) site choice, interacts with Rna15p, Fip1p, Pap1p, and Pcf11p" YAL029C MYO4 1 18 2.1 0.5121 0.682952261 iYAL029C 0.522747814 0.607808341 0.543586851 "MYO4 -- cell polarity -- Myosin heavy chain, class V" YBR153W RIB7 1 17 2.1 0.5121 0.707637518 iYBR152W 0.358297414 0.808250081 0.375926523 "RIB7 -- flavin biosynthesis -- HTP reductase, second step in the riboflavin biosynthesis pathway" YDR337W MRPS28 1 17 2.1 0.5121 0.378693576 iYDR336W 0.302918241 0.692833045 0.638702912 MRPS28 -- protein synthesis -- Mitochondrial ribosomal small subunit (E. coli S15) YDL189W YDL189W 0.9 16 2.1 0.5121 0.340982574 iYDL190C 0.555874255 0.341500399 0.897011046 YDL189W -- unknown -- unknown function YDR476C YDR476C 0.9 15 2.1 0.5121 0.184439074 iYDR476C 0.226848083 0.644474485 0.597959352 YDR476C -- unknown -- unknown function YGL246C RAI1 0.9 16 2.1 0.5121 0.579245588 iYGL246C 0.233313939 0.834119497 0.228810854 RAI1 -- unknown -- binds and enhances function of nuclear exonuclease Rat1p YJL016W YJL016W 0.9 16 2.1 0.5121 0.688977029 iYJL017W 0.622944229 0.875523687 0.802713488 "YJL016W -- unknown -- unknown function, overlaps with YJL015C" YJL154C VPS35 0.9 15 2.1 0.5121 0.480588141 iYJL154C 0.257558621 0.677199046 0.123416956 "VPS35 -- vacuolar protein targeting -- vacuolar sorting, mutant has vacuoles of normal morphology" YJR111C YJR111C 0.9 15 2.1 0.5121 0.307022704 iYJR111C 0.559054504 0.415967855 0.509708549 YJR111C -- unknown -- unknown function YKR072C SIS2 0.9 16 2.1 0.5121 0.29911655 iYKR072C 0.642806738 0.470213138 0.523864821 "SIS2 -- cell cycle and ion homeostasis -- ion homeostasis, plays a role in resistance to elevated NaCl or LiCl" YLR134W PDC5 0.9 16 2.1 0.5121 0.738893901 iYLR133W 0.605169067 0.895169917 0.794087667 PDC5 -- glycolysis -- Pyruvate decarboxylase isozyme 2 YML043C RRN11 0.9 16 2.1 0.5121 0.285320295 iYML043C 0.244048894 0.357382283 0.572458167 RRN11 -- transcription -- Component of RNA polymerase I core transcription factor (CF) along with Rrn6p and Rrn7p YMR177W MMT1 0.9 16 2.1 0.5121 0.352744201 iYMR176W 0.14440617 0.677593782 0.227987421 MMT1 -- mitochondrial iron transport -- mitochondrial iron accumulation YNL246W YNL246W 0.9 16 2.1 0.5121 0.375110539 iYNL247W 0.251721176 0.43944129 0.082742507 YNL246W -- unknown -- similarity to Drosophila melanogaster SET protein YNL252C MRPL17 0.9 16 2.1 0.5121 0.316808233 iYNL252C 0.646585512 0.60030229 0.416522669 MRPL17 -- protein synthesis -- Mitochondrial ribosomal large subunit YER089C PTC2 0.8 13 2.1 0.5121 0.603140835 iYER089C 0.553514023 0.624756335 0.663712536 "PTC2 -- unknown -- Protein serine/threonine phosphatase of PP2C family, negative regulator of unfolded protein response (UPR) pathway" YFR034C PHO4 0.8 13 2.1 0.5121 0.403388759 iYFR034C 0.550696046 0.142201096 "PHO4 -- phosphate signaling -- Basic helix-loop-helix (bHLH) transcription factor required for expression of phosphate pathway, inactivated by hyperphosphorylation by Pho80p-Pho85p cyclin-dependent protein kinase" YHR130C YHR130C 0.8 15 2.1 0.5121 0.295625692 0.113922011 YHR130C -- unknown -- unknown function YIL130W YIL130W 0.8 15 2.1 0.5121 0.458354484 iYIL131C 0.195731739 0.516201117 0.171849823 YIL130W -- unknown -- similarity to transcription factorshas Zn[2]-Cys[6] fungal-type binuclear cluster domain in the N-terminal region YJL006C CTK2 0.8 14 2.1 0.5121 0.8729966 iYJL006C itL(UAA)J 0.600795283 0.611327473 0.934666338 0.398725498 0.496256068 "CTK2 -- transcription -- C-terminal domain (RNA polymerase II CTD) kinase beta subunit, cyclin-related protein component that interacts with the cyclin-dependent protein kinase Ctk1p" YJL091C YJL091C 0.8 13 2.1 0.5121 0.680673179 iYJL091C 0.679580421 0.858403215 0.617202729 YJL091C -- unknown -- unknown function YLR460C YLR460C 0.8 14 2.1 0.5121 0.310058348 iYLR460C-0 iYLR460C-1 0.720026135 0.941672582 0.744145917 0.798651722 0.641580208 YLR460C -- unknown -- strong similarity to Ycr102p YMR039C TSP1 0.8 14 2.1 0.5121 0.067931506 iYMR039C 0.088594506 0.063164679 0.038695505 TSP1 -- transcription -- Transcriptional coactivatormay be involved in the release of TFIIB from the transcription complex during RNA polymerase II transcription initiation YPR140W YPR140W 0.8 15 2.1 0.5121 0.428198286 iYPR139C 0.17880289 0.620283019 0.050173429 YPR140W -- unknown -- Putative acyltransferase with similarity to human Barth syndrome gene tafazzin YBR271W YBR271W 0.7 11 2.1 0.5121 0.133539353 iYBR270C 0.335562457 0.299514523 0.676974144 YBR271W -- unknown -- Putative SAM-dependent methyltransferase YEL018W YEL018W 0.7 13 2.1 0.5121 0.36547337 iYEL019C 0.117619882 0.361777628 0.069681771 YEL018W -- unknown -- unknown function YGR028W MSP1 0.7 12 2.1 0.5121 0.915025324 iYGRWdelta14 itE(UUC)G3 0.666934641 0.69558588 0.98499601 0.449140921 0.66677409 "MSP1 -- mitochondrial protein targeting -- Intra-mitochondrial sorting protein, member of AAA family of ATPases" YGR227W DIE2 0.7 11 2.1 0.5121 0.082162692 iYGR226C 0.216694051 0.104288499 0.178639019 DIE2 -- glucosylation? -- Glucosyltransferase involved in the terminal glucosylation step of lipid-linked oligosaccharide YJL193W YJL193W 0.7 13 2.1 0.5121 0.91841175 iYJL194W 0.684307729 0.817158819 0.602565137 "YJL193W -- unknown -- similarity to Sly41p, member of triose phosphate translocator family of membrane transporters" YKL045W PRI2 0.7 13 2.1 0.5121 0.298054175 iYKL046C 0.379005976 0.66576154 0.391872309 "PRI2 -- DNA replication -- DNA primase large subunit (DNA polymerase alpha 58 kDa subunit), involved in synthesis of RNA primers for Okazaki fragments" YKL149C DBR1 0.7 11 2.1 0.5121 0.575250407 iYKL149C 0.107250142 0.783054713 0.21973058 DBR1 -- mRNA splicing -- Lariat RNA debranching enzyme involved in turnover of excised spliceosomal introns YNL001W DOM34 0.7 13 2.1 0.5121 0.686128859 iYNL002C 0.553694885 0.824132284 0.268587361 DOM34 -- protein synthesis (putative) -- translation YNL119W YNL119W 0.7 13 2.1 0.5121 0.659949497 0.848592401 YNL119W -- unknown -- Protein possibly involved in cytoplasmic ribosome function YOR084W YOR084W 0.7 12 2.1 0.5121 iYOR083W 0.671454247 0.847499155 YOR084W -- unknown -- unknown function YHR029C YHR029C 0.6 11 2.1 0.5121 0.615182591 iYHR029C 0.463930358 0.783568666 0.296058586 YHR029C -- unknown -- similarity to Pseudomonas aureofaciens phzC involved in phenazine antibiotic synthesistranscription induced by the drug FK506 in a GCN4-dependent manner YIL016W SNL1 0.6 11 2.1 0.5121 0.448033026 YIL017C iYIL017C 0.368180333 0.308125964 0.912696454 0.240219408 0.740582399 SNL1 -- nuclear protein targeting -- interacts genetically with nuclear pore complex proteins YJL087C TRL1 0.6 10 2.1 0.5121 0.274476999 0.813889784 "TRL1 -- tRNA splicing -- tRNA ligase required for tRNA splicing, has 3 activities in one polypeptide" YMR267W PPA2 0.6 11 2.1 0.5121 0.128021847 iYMR266W 0.360188419 0.265790111 0.358473824 "PPA2 -- oxidative phosphorylation -- Inorganic pyrophosphatase, mitochondrial" YOL093W YOL093W 0.6 9 2.1 0.5121 0.084244943 iYOL094C 0.548142064 0.300008228 0.174790356 YOL093W -- unknown -- unknown function YPL254W HFI1 0.6 10 2.1 0.5121 0.477861554 iYPL255W 0.340678831 0.675306509 0.620981831 "HFI1 -- transcription -- Component of ADA complex, interacts functionally with histone H2Ai" YDR440W DOT1 0.4 9 2.1 0.5121 0.333871492 iYDR439W-0 iYDR439W-1 0.326924109 0.340097965 0.269114126 0.357031186 0.578849722 "DOT1 -- meiosis, checkpoint; transcriptional silencing -- cell cycle arrest at the pachytene stage of meiosis in a zip1 mutant" YJL033W HCA4 0.4 8 2.1 0.5121 0.471179355 iYJL034W 0.54241507 0.468783043 0.199910929 "HCA4 -- rRNA processing -- Probable RNA helicase CA4, involved in ribosomal RNA processing" YJR055W HIT1 0.4 9 2.1 0.5121 0.597696084 iYJR054W YJLWdelta16 0.345043814 0.851484963 0.800957702 0.189816307 0.789540385 HIT1 -- unknown -- growth at high temperature YKL176C YKL176C 1.1 21 2 0.4969 1 0.92419664 iYKL176C 0.983139099 0.798983625 0.093216281 YKL176C -- unknown -- unknown function YOR354C YOR354C 0.9 16 2 0.4969 1 0.576437806 iYOR354C-0 iYOR354C-1 0.925420027 0.965657265 0.395176252 0.610055866 0.242568228 YOR354C -- unknown -- unknown function YPL082C MOT1 0.9 17 2 0.4969 1 0.607770428 iYPL082C IntYPL081W 0.953480189 0.963957202 0.302852079 0.128651237 0.821085747 "MOT1 -- transcription -- Transcriptional Accessory Protein (TAF) involved in RNA polymerase II transcriptional repression through interaction with TATA-binding protein (TBP), member of Snf2p family of DNA helicases" YER046W YER046W 0.7 13 2 0.4969 1 0.735869296 iYER045C-0 iYER045C-1 0.939890272 0.95689995 0.612945493 0.762335248 0.764644852 YER046W -- unknown -- unknown function YGR258C RAD2 0.7 13 2 0.4969 1 0.546212594 iYGR258C-0 iYGR258C-1 0.962064635 0.356930106 0.275056397 0.522303783 0.294641216 "RAD2 -- DNA repair, nucleotide excision -- Structure-specific single-stranded DNA endonuclease of nucleotide excision repairosome" YDL215C GDH2 1.9 34 2 0.4969 0.292116812 iYDL215C 0.134446708 0.517060579 0.604297694 "GDH2 -- glutamate metabolism -- Glutamate dehydrogenase (NAD), primary pathway for generating ammonia from glutamate" YKL150W MCR1 1.8 34 2 0.4969 0.733795666 iYKL151C 0.893278506 0.605220754 0.363860775 MCR1 -- electron carrier -- NADH-cytochrome b5 reductase YBL050W SEC17 1.7 32 2 0.4969 0.638227005 iYBL051C 0.258890752 0.955538085 0.189406969 SEC17 -- secretion -- fusion of vesicles to target membranes as well as for vacuolar fusionhomolog of mammalian alpha-SNAP YDR457W TOM1 1.6 29 2 0.4969 0.615984031 iYDR456W 0.587879778 0.443954082 0.479228846 "TOM1 -- cell cycle, G2/M -- the G2/M transition, has similarity to Rsp5p, a ubiquitin-protein ligase" YPL169C MEX67 1.6 28 2 0.4969 0.487976291 iYPL169C 0.642040715 0.453351595 0.692976856 MEX67 -- mRNA export -- the export of mRNA from the nucleus to the cytoplasm YIL154C YIL154C 1.3 24 2 0.4969 0.196175118 iYIL154C 0.197914728 0.399920192 0.225890985 YIL154C -- stress response -- control of mitochondrial sugar utilization YMR184W YMR184W 1.3 26 2 0.4969 0.414278776 iYMR183C 0.417494197 0.428375765 YMR184W -- unknown -- unknown function YBR077C YBR077C 1.2 23 2 0.4969 0.563296308 iYBR077C 0.274647185 0.703396545 0.157032978 YBR077C -- unknown -- unknown function YBR091C MRS5 1.2 23 2 0.4969 0.711197294 iYBR091C 0.217626699 0.811647173 0.292312698 "MRS5 -- mitochondrial protein targeting -- Essential component of mitochondrial import machinery, required for transfer of hydrophobic inner membrane carrier proteins across the intermembrane space" YIL023C YIL023C 1.2 22 2 0.4969 0.37631965 iYIL023C 0.600933543 0.875432194 0.521628093 YIL023C -- unknown -- similarity to Atx2 YBR004C YBR004C 1.1 21 2 0.4969 0.663916165 iYBR004C 0.634299954 0.863607342 0.696986787 YBR004C -- unknown -- expressed between 3 and 6 hours after transfer to sporulation medium YDR516C YDR516C 1.1 20 2 0.4969 0.638987428 iYDR516C 0.247189943 0.804492718 0.383963862 YDR516C -- unknown -- similarity to Glk1p YER167W BCK2 1.1 20 2 0.4969 0.472228457 iYER166W 0.528316508 0.37858524 0.321069433 BCK2 -- signaling -- the SIT4 pathway for CLN activation and in suppression of lethality due to mutations in the kinase C pathway YJR113C YJR113C 1.1 22 2 0.4969 0.674545794 0.896848603 "YJR113C -- protein synthesis -- Probable mitochondrial ribosomal protein S7 of small subunit, homolog of E. coli ribosomal protein S7" YLR099C ICT1 1.1 21 2 0.4969 0.54261646 iYLR099C 0.308696027 0.744938292 0.39896874 ICT1 -- copper ion homeostasis (putative) -- normal sensitivity to copper YNR033W ABZ1 1.1 20 2 0.4969 0.412366345 YNR032C-A iYNR032C-A 0.323755764 0.067344241 0.680047885 0.376732195 0.092101149 ABZ1 -- PABA biosynthesis -- Para-aminobenzoate synthase YOR197W YOR197W 1.1 21 2 0.4969 0.250198331 iYOR196C 0.226320001 0.435024603 0.184728051 YOR197W -- unknown -- unknown function YBR038W CHS2 1 19 2 0.4969 0.398018098 iYBR037C 0.179275612 0.44287786 0.290854451 "CHS2 -- cell wall biogenesis -- Chitin synthase II, responsible for primary septum disk" YDR357C YDR357C 1 19 2 0.4969 0.74106253 iYDR357C 0.500165262 0.963458901 0.37998848 YDR357C -- unknown -- unknown function YGR255C COQ6 1 19 2 0.4969 0.701068203 iYGR255C itT(UGU)G2 0.739055864 0.427839586 0.828794715 0.623700455 0.496115319 COQ6 -- ubiquinone biosynthesis -- Monooxygenase required for coenzyme Q (ubiquinone) biosynthesis YHR107C CDC12 1 19 2 0.4969 0.371195916 iYHR107C 0.128650586 0.652513966 0.221978558 "CDC12 -- cytokinesis -- Septin, component of 10 nm filaments of mother-bud neckinvolved in cytokinesis" YJR086W STE18 1 19 2 0.4969 0.762724084 iYJR085C 0.076939899 0.856509829 0.442413905 "STE18 -- signaling, pheromone pathway -- Gamma subunit of guanine nucleotide-binding mediates signal transduction by pheromones during mating" YKL203C TOR2 1 18 2 0.4969 0.419075977 iYKL203C 0.233027596 0.244219534 0.269566737 "TOR2 -- signaling, cell cycle, meiosis and actin cytoskeleton organization -- Phosphatidylinositol-4 kinase (PI-4 kinase), involved in cell growth and sensitivity to the immunosuppressant rapamycin, has similarity to Tor1p" YBR273C YBR273C 0.9 18 2 0.4969 0.159460813 iYBR273C 0.401904817 0.338517239 0.643220134 YBR273C -- unknown -- unknown function YER130C YER130C 0.9 17 2 0.4969 0.894534184 iYER130C 0.974083212 0.986609664 0.494533635 "YER130C -- unknown -- unknown function, has two tandem zinc finger domains" YJL093C TOK1 0.9 18 2 0.4969 0.387682883 iYJL093C 0.245531904 0.826656026 0.216987981 TOK1 -- transport -- Two-domain outwardly-rectifying voltage-gated potassium channel YNL177C YNL177C 0.9 16 2 0.4969 0.702834466 iYNL177C 0.802971487 0.729692668 0.810347628 YNL177C -- unknown -- unknown function YNL321W YNL321W 0.9 16 2 0.4969 0.16672256 iYNL322C 0.25315304 0.203351595 0.230145319 YNL321W -- unknown -- Member of calcium permease family of membrane transporters YOR329C SCD5 0.9 16 2 0.4969 0.104637116 iYOR329C 0.256928862 0.125893437 0.415120112 SCD5 -- secretion -- Multicopy suppressor of clathrin deficiency YBR085W AAC3 0.8 15 2 0.4969 0.950305482 iYBR084C-A 0.985655862 0.668063165 0.377094972 "AAC3 -- transport -- ADP/ATP transporter protein, member of mitochondrial carrier (MCF) family" YDL018C ERP3 0.8 15 2 0.4969 0.566377755 iYDL018C 0.436640347 0.839349017 0.564804469 ERP3 -- membrane trafficking; secretion (putative) -- similarity to COPII-coated vesicle proteins Emp24p and Erv25p YDL179W PCL9 0.8 15 2 0.4969 0.299338776 iYDL180W 0.703820625 0.70302467 0.836206897 PCL9 -- cell cycle -- Cyclin that associates with Pho85p YDL246C YDL246C 0.8 15 2 0.4969 0.392415661 iYDL246C-0 iYDL246C-1 0.276325308 0.430814924 0.335308993 0.362490024 0.610062893 YDL246C -- unknown -- similarity to Sor1p YDR364C CDC40 0.8 15 2 0.4969 0.381558699 iYDR364C 0.58525605 0.834956105 0.30196584 "CDC40 -- cell cycle and mRNA splicing -- the second catalytic step of mRNA splicing, member of WD (WD-40) repeat family" YER010C YER010C 0.8 15 2 0.4969 0.182523311 iYER010C-0 iYER010C-1 0.527797579 0.251308313 0.543128655 0.680606544 0.275584795 YER010C -- unknown -- unknown function YER164W CHD1 0.8 16 2 0.4969 0.516580865 iYER163C-0 iYER163C-1 0.356008532 0.245960241 0.604470157 0.274582408 0.342168869 CHD1 -- transcription -- similarity to mouse CHD (Chromodomain-Helicase-DNA-binding) protein YFL046W YFL046W 0.8 15 2 0.4969 0.029157662 iYFL047W 0.22315457 0.052274541 0.012751787 YFL046W -- unknown -- weak similarity to myosin heavy chain A YHR113W YHR113W 0.8 15 2 0.4969 0.524585973 iYHR112C 0.091854379 0.84382457 0.254695262 YHR113W -- unknown -- similarity to vacuolar aminopeptidase Lap4p/Ape1p YHR123W EPT1 0.8 13.5 2 0.4969 0.687963301 iYHR122W 0.89508803 0.556652678 0.815202587 "EPT1 -- phospholipid metabolism -- sn-1,2-Diacylglycerol ethanolaminephosphotransferase" YJL062W LAS21 0.8 14 2 0.4969 0.103812557 iYJL063C 0.263715131 0.259014278 0.52365671 LAS21 -- unknown -- addition of a side chain to the glycosylphospatidylinositol (GPI) core structure YJR003C YJR003C 0.8 14 2 0.4969 0.719514237 iYJR003C 0.408269549 0.960312979 0.321206744 YJR003C -- unknown -- weak similarity to human collagen alpha 3 (VI) chain precursor YJR041C YJR041C 0.8 14 2 0.4969 0.399527144 iYJR041C 0.11837298 0.904522698 0.284805027 YJR041C -- unknown -- similarity to Podospora anserina NADH dehydrogenase chain 4 YJR103W URA8 0.8 16 2 0.4969 0.462201301 iYJR102C 0.550273905 0.839751853 0.703182268 "URA8 -- pyrimidine biosynthesis -- CTP synthase, last step in pyrimidine biosynthesis pathway" YKL078W JA2 0.8 14 2 0.4969 0.064395088 iYKL079W 0.214677889 0.174860335 0.20815863 "JA2 -- unknown -- RNA helicase of DEAH box family, possible pre-mRNA splicing factor" YML027W YOX1 0.8 14 2 0.4969 0.697644505 iYML028W 0.600473122 0.697786414 0.307825228 YOX1 -- unknown -- homeodomain that binds tRNA-Leu gene YOL029C YOL029C 0.8 14 2 0.4969 0.32670063 iYOL029C 0.620225459 0.620258372 0.604871225 YOL029C -- unknown -- unknown function YOR017W PET127 0.8 15 2 0.4969 0.444692202 iYOR016C 0.045248503 0.665765461 0.035275339 PET127 -- protein synthesis -- Mitochondrial membrane-associated stability and processing of mitochondrial mRNAs YAL020C ATS1 0.7 13 2 0.4969 0.354206138 iYAL020C 0.085744049 0.66475991 0.09901708 "ATS1 -- cytoskeleton (putative) -- similarity to human RCC1 protein, suppressor of mutations in alpha tubulin" YBR238C YBR238C 0.7 12 2 0.4969 0.296238126 iYBR238C 0.270411272 0.472475932 0.482521947 YBR238C -- unknown -- unknown function YDL098C SNU23 0.7 12 2 0.4969 0.534259022 iYDL098C 0.379016246 0.680266111 0.277486489 SNU23 -- mRNA splicing (putative) -- Component of U4/U6.U5 snRNP YDR348C YDR348C 0.7 12 2 0.4969 0.298649601 iYDR348C 0.277321094 0.585723493 0.416356877 YDR348C -- unknown -- unknown function YDR518W EUG1 0.7 13 2 0.4969 0.487662685 iYDR517W 0.293587431 0.916201117 0.311322287 "EUG1 -- protein folding -- disulfide isomerase, required only in the absence of Pdi1p" YFR005C SAD1 0.7 13 2 0.4969 0.638629536 iYFR005C 0.053423992 0.89584996 0.093729695 "SAD1 -- mRNA splicing, snRNP assembly -- snRNP assembly factor required for pre-mRNA splicing" YGR117C YGR117C 0.7 11 2 0.4969 0.985458171 iYGR117C 0.959779417 0.976855547 0.00489229 YGR117C -- unknown -- unknown function YHR084W STE12 0.7 12 2 0.4969 0.277843943 iYHR083W 0.764964804 0.713416695 0.943063678 "STE12 -- mating and pseudohyphal growth -- Transcription factor that binds to pheromone response element (PRE) to regulate genes required for mating, also functions with Tec1p to regulate genes required for filamentous growth" YJL172W CPS1 0.7 13 2 0.4969 0.529001939 iYJL173C 0.367959432 0.682043097 0.4896249 "CPS1 -- protein degradation -- Gly-X carboxypeptidase yscS, involved in nitrogen metabolism" YJR141W YJR141W 0.7 13 2 0.4969 0.783778658 iYJR140C 0.56016081 0.974429297 0.301401869 YJR141W -- unknown -- Essential unknown function YMR129W POM152 0.7 13 2 0.4969 0.472794299 iYMR128W 0.201083738 0.625524562 0.441351308 POM152 -- nuclear protein targeting -- Nuclear pore membrane glycoproteintype II integral membrane N-terminal region on pore side and C-terminal region in the cisternae YNL021W HDA1 0.7 13 2 0.4969 0.338109114 iYNL022C 0.590932705 0.683450303 0.232342007 "HDA1 -- chromatin structure -- Component of histone deacetylase A, 75 kDa subunit" YOL115W TRF4 0.7 13 2 0.4969 0.215776879 iYOL116W 0.365485136 0.309141776 0.525466963 "TRF4 -- mitosis, chromosome condensation -- Protein required in the absence of Top1p" YOR144C EFD1 0.7 12 2 0.4969 0.324736068 iYOR144C 0.585856919 0.68780573 0.590234102 EFD1 -- recombination (putative) -- stability of direct DNA repeats YDR260C SWM1 0.6 11 2 0.4969 0.834284553 iYDR260C 0.503522704 0.639590223 0.191699559 SWM1 -- sporulation -- spore wall assembly YGL155W CDC43 0.6 11 2 0.4969 0.563142135 iYGL156W 0.191003912 0.851173671 0.246958432 "CDC43 -- protein processing -- Geranylgeranyltransferase type I beta subunit, recognizes a C-terminal CXXL motif" YHR149C YHR149C 0.6 11 2 0.4969 iYHR149C 0.231423021 0.406227313 YHR149C -- unknown -- unknown function YJL010C YJL010C 0.6 10 2 0.4969 0.414603318 iYJL010C 0.485388053 0.438573849 0.485674939 YJL010C -- unknown -- unknown function YJR043C POL32 0.6 12 2 0.4969 0.251263418 iYJR043C itM(CAU)J3 0.240930716 0.544899108 0.365915444 0.214844374 0.535934848 POL32 -- DNA replication -- Small (55 kDa) subunit of DNA polymerase delta YKR003W YKR003W 0.6 11 2 0.4969 0.49037737 iYKR002W 0.768351273 0.881243957 0.720542578 "YKR003W -- unknown -- similarity to human oxysterol-binding protein (OSBP),member of KES1/HES1/OSH1/YKR003W family of oxysterol-binding protein" YMR088C YMR088C 0.6 10 2 0.4969 0.388995759 iYMR088C 0.414192694 0.726957783 0.211470419 YMR088C -- unknown -- Member of multidrug-resistance 14-spanner family of major facilitator superfamily (MFS-MDR) YNL282W POP3 0.6 11 2 0.4969 0.5245391 iYNL283C 0.533663139 0.941033138 0.266422082 "POP3 -- rRNA and tRNA processing -- Component of both RNase MRP and RNase P, involved in processing of both rRNA and tRNA precursors" YNR048W YNR048W 0.6 11 2 0.4969 0.322399935 iYNR047W 0.426861031 0.23817168 0.570415727 YNR048W -- unknown -- unknown function YOR138C YOR138C 0.6 10 2 0.4969 0.408966781 iYOR138C 0.37116245 0.621243885 0.233585232 YOR138C -- unknown -- unknown function YDR428C YDR428C 0.4 9 2 0.4969 0.488163653 iYDR428C 0.27707593 0.582292235 0.141406758 YDR428C -- unknown -- unknown function YPR029C APL4 1.1 21 1.9 0.4819 1 0.743767935 iYPR029C 0.972814298 0.600789558 0.657417117 "APL4 -- secretion -- Gamma-adaptin, large subunit of clathrin-associated protein (AP) complex" YNL101W YNL101W 1 20 1.9 0.4819 1 0.900978161 iYNL102W 0.97040561 0.720649895 0.782934255 YNL101W -- unknown -- Putative membrane transporter of amino acid/auxin permease (AAAP) family YDR189W SLY1 0.9 17 1.9 0.4819 1 0.66881738 iYDR188W 0.67368349 0.38706218 0.282189929 "SLY1 -- secretion -- vesicle trafficking between endoplasmic reticulum and Golgi, member of Sec1p family" YHR091C MSR1 0.8 15 1.9 0.4819 1 0.7250558 iYHR091C 0.958591963 0.899691358 0.121018611 MSR1 -- protein synthesis -- Arginyl-tRNA synthetase of mitochondria YBR199W KTR4 2.2 45 1.9 0.4819 0.552615339 iYBR198C 0.328981648 0.642617717 0.381243957 "KTR4 -- protein glycosylation -- Alpha-1,2-mannosyltransferase of KRE2 family" YOR317W FAA1 1.9 37 1.9 0.4819 0.618787566 iYOR316C-0 iYOR316C-1 0.705008664 0.917170267 0.514099259 0.429768555 0.557940942 FAA1 -- fatty acid metabolism -- Long-chain fatty acid CoA ligase (fatty acid activator 1)can incorporate exogenous myristate into myristoyl-CoA and other fatty acids to the CoA derivatives YOR382W YOR382W 1.9 38 1.9 0.4819 0.345218814 iYOR381W-0 iYOR381W-1 0.34695742 0.313789008 0.122292103 0.418469077 0.10046902 YOR382W -- unknown -- unknown function YDR309C GIC2 1.8 36 1.9 0.4819 0.43899549 iYDR309C 0.14644484 0.502154828 0.293054771 "GIC2 -- bud emergence -- Putative effector of Cdc42p, important for bud emergence" YCR073W-A 1.7 34 1.9 0.4819 0.221246269 iYCR073C 0.522376288 0.326576217 0.66733806 YCL045C YCL045C 1.6 31 1.9 0.4819 0.293328173 0.626347404 YCL045C -- unknown -- unknown function YBR234C ARC40 1.5 28 1.9 0.4819 0.469168525 iYBR234C 0.146099442 0.531260561 0.151407599 "ARC40 -- cytoskeleton -- Component of ARP2/3 actin-organizing complex, involved in actin assembly and function" YEL065W SIT1 1.5 29 1.9 0.4819 0.570277845 iYEL066W 0.553119036 0.620826195 0.658659218 "SIT1 -- transport -- Ferrioxamine B permease, member of yeast-specific multidrug-resistance (MFS-MDR) family of major facilitator superfamily (MFS)" YLR250W SSP120 1.5 29 1.9 0.4819 0.398411788 iYLR249W 0.53231936 0.673550052 0.492142616 SSP120 -- secretion -- Putative secretory protein YML100W TSL1 1.3 27 1.9 0.4819 0.365735626 iYML101C 0.352351623 0.450828882 0.365936191 TSL1 -- trehalose metabolism -- Component of trehalose-6-phosphate synthase/phosphatase complexalternate third subunit with Tps3p YCR048W ARE1 1.2 24 1.9 0.4819 0.47167651 0.525503574 ARE1 -- sterol metabolism -- Acyl-CoA YDR182W CDC1 1.2 23 1.9 0.4819 0.288432966 iYDR181C 0.574142742 0.673245614 0.348183089 "CDC1 -- Mn2+ ion homeostasis -- ion homeostatisaffects bud emergence, mating, macromolecular synthesis, intrachromosomal recombination, and nuclear division" YKL087C CYT2 1.2 24 1.9 0.4819 0.275094974 iYKL087C 0.586220757 0.397920832 0.674760023 CYT2 -- cytochrome c1 biosynthesis -- Holocytochrome-c1 synthase YDR294C DPL1 1.1 23 1.9 0.4819 0.483271265 iYDR294C 0.30994773 0.785593289 0.768734371 DPL1 -- phospholipid metabolism -- Dihydrosphingosine-1-phosphate lyase YFL041W FET5 1.1 21 1.9 0.4819 0.771680832 iYFL042C 0.115843439 0.965921788 0.283133016 FET5 -- transport -- Multicopper oxidase involved in ferrous iron transport YOR267C YOR267C 1.1 22 1.9 0.4819 0.087466272 iYOR267C 0.099866123 0.051643571 0.032865833 YOR267C -- unknown -- Serine/threonine protein kinase with similarity to members of NPR1 subfamily YBR080C SEC18 1 20 1.9 0.4819 0.358893445 iYBR080C 0.601104571 0.704868316 0.580301686 "SEC18 -- secretion -- fusion of vesicles to target membranes as well as for vacuolar fusion, homolog of mammalian NSF protein, member of AAA family of ATPases" YBR246W YBR246W 1 18 1.9 0.4819 0.33918654 0.841228419 YBR246W -- unknown -- unknown function YFR031C SMC2 1 19 1.9 0.4819 0.441619256 iYFR031C 0.786199315 0.335320657 0.589810747 "SMC2 -- mitosis, chromosome condensation and segregation -- Subunit of condensin protein complex required for chromosome condensation and segregation, coiled-coil SMC family" YIL046W MET30 1 19 1.9 0.4819 0.603593128 iYIL047C 0.101755046 0.858998145 0.002842755 "MET30 -- sulfur amino acid metbolism -- F-box targets proteins for ubiquitination by interacting with the SCF complex (Skp1p-Cdc53p-Cdc34p), regulates sulfur assimilation genes in response to S-adenosylmethionine levels, contains five WD (WD-40) repeats" YMR261C TPS3 1 19 1.9 0.4819 0.379917585 iYMR261C 0.488454505 0.258137286 0.602694584 "TPS3 -- trehalose utilization -- Component of trehalose-6-phosphate synthase/phosphatase complex, alternative third subunit with Tls1p" YPL173W MRPL40 1 18 1.9 0.4819 0.191492259 iYPL174C 0.481889484 0.318948133 0.621986341 MRPL40 -- protein synthesis -- Mitochondrial ribosomal large subunit YPR067W ISA2 1 21 1.9 0.4819 0.161646505 iYPR066W 0.535922721 0.260255387 0.627492396 ISA2 -- unknown -- Mitochondrial iron metabolism YCL010C YCL010C 0.9 17 1.9 0.4819 0.335180226 iYCL010C 0.412832993 0.204229848 0.51754386 YCL010C -- unknown -- unknown function YEL043W YEL043W 0.9 18 1.9 0.4819 0.563936023 iYEL044W 0.805427218 0.359006007 0.450341479 YEL043W -- unknown -- unknown function YGL013C PDR1 0.9 17 1.9 0.4819 0.407634791 iYGL013C 0.642780309 0.61500399 0.611373166 PDR1 -- transport -- Transcription factor related to Pdr3p YGR019W UGA1 0.9 16 1.9 0.4819 0.540987766 iYGR018C 0.681369969 0.803965232 0.624234612 "UGA1 -- GABA metabolism -- 4-Aminobutyrate aminotransferase (GABA transaminase), produces gamma-aminobutyric acid" YHR009C YHR009C 0.9 17 1.9 0.4819 0.929428446 iYHR009C IntYHR010W 0.985386052 0.925097389 0.443815478 0.235412299 0.250719987 YHR009C -- unknown -- unknown function YJL129C TRK1 0.9 17 1.9 0.4819 0.235497978 iYJL129C 0.31098387 0.455626496 0.510957138 "TRK1 -- transport -- Potassium transporter of plasma membrane, high affinity, member of potassium transporter (TRK) family of membrane transporters" YJL164C TPK1 0.9 18 1.9 0.4819 0.302967983 iYJL164C 0.324722969 0.455206676 0.18955276 "TPK1 -- signaling -- cAMP-dependent protein kinase 1, catalytic chainprotein kinase A" YKR088C YKR088C 0.9 17 1.9 0.4819 0.506370467 iYKR088C 0.48211271 0.892019154 0.412586799 YKR088C -- unknown -- unknown function YNL152W YNL152W 0.9 18 1.9 0.4819 0.423209516 iYNL153C 0.811096033 0.24764565 0.112739138 YNL152W -- unknown -- unknown function YNL158W YNL158W 0.9 17 1.9 0.4819 0.388122519 iYNL159C 0.202857208 0.572705507 0.278820305 YNL158W -- unknown -- unknown function YNR040W YNR040W 0.9 17 1.9 0.4819 0.626781773 iYNR039C 0.140885804 0.555227454 0.374450015 YNR040W -- unknown -- unknown function YPL064C YPL064C 0.9 17 1.9 0.4819 0.093944517 iYPL064C 0.547384783 0.065789474 0.61797209 YPL064C -- unknown -- unknown function YPR024W YME1 0.9 17 1.9 0.4819 0.13020376 iYPR023C 0.216326888 0.207438493 0.331531822 "YME1 -- mitochondrial protein processing -- Mitochondrial zinc-dependent protease and member of AAA family of ATPases, responsible for degradation of improperly folded proteins in the intermembrane space" YAL056W YAL056W 0.8 15 1.9 0.4819 0.44702659 iYAL058C-A 0.511098201 0.421769256 0.639863548 YAL056W -- unknown -- unknown function YBR003W COQ1 0.8 15 1.9 0.4819 iYBR002C 0.67035393 0.838531514 "COQ1 -- ubiquinone biosynthesis -- Hexaprenyl pyrophosphate synthetase, catalyzes the first step in coenzyme Q (ubiquinone) biosynthesis pathway" YBR017C KAP104 0.8 16 1.9 0.4819 0.574058271 iYBR017C 0.320037679 0.813597491 0.362250599 "KAP104 -- nuclear protein targeting -- Transportin, beta-karyopherin involved in nuclear transport of mRNA-binding proteins" YBR021W FUR4 0.8 16 1.9 0.4819 0.446747957 iYBR020W 0.389804763 0.650837989 0.695877561 "FUR4 -- transport -- Uracil permease, member of uracil/allantoin permease family of membrane transporters" YCL020W 0.8 15 1.9 0.4819 0.584226981 iYCL022C tE(UUC)C 0.700121395 0.793162827 0.445492662 0.546458739 0.541089268 YCL047C YCL047C 0.8 16 1.9 0.4819 0.288054937 iYCL047C 0.425317233 0.641687505 0.296656064 YCL047C -- unknown -- unknown function YDL217C TIM22 0.8 14 1.9 0.4819 iYDL217C 0.621085835 0.752198112 TIM22 -- mitochondrial protein targeting -- Essential mitochondrial inner membrane import of mitochondrial inner membrane proteins YIL044C AGE2 0.8 16 1.9 0.4819 0.298876138 iYIL044C 0.128143576 0.737190742 0.057605543 "AGE2 -- unknown -- similarity to Gcs1p, member of Gcs1p/Glo3p/Sps18p family" YJL179W PFD1 0.8 15 1.9 0.4819 0.723627592 iYJL180C 0.190133943 0.530782976 0.069231414 "PFD1 -- protein folding -- Component of Gim protein complex that promotes formation of functional alpha- and gamma-tubulin and actin, has similarity to bovine prefoldin subunit 1" YJR116W YJR116W 0.8 15 1.9 0.4819 0.58599395 iYJR115W 0.422037536 0.498308089 0.290767 YJR116W -- unknown -- unknown function YLR097C YLR097C 0.8 15 1.9 0.4819 0.556684845 iYLR097C 0.375249978 0.850547857 0.528264626 "YLR097C -- unknown -- unknown function, contains an F-box" YLR237W THI7 0.8 16 1.9 0.4819 0.165076979 iYLR236C 0.303846762 0.394964206 0.180284703 THI7 -- transport -- Thiamine transport protein YNL290W RFC3 0.8 16 1.9 0.4819 0.385828083 iYNL291C 0.413980677 0.891859537 0.225458899 "RFC3 -- DNA replication -- Replication factor C, 40 kDa subunit, member of DEAD box family of putative helicase proteins" YOL031C YOL031C 0.8 15 1.9 0.4819 0.366301862 iYOL031C 0.224688506 0.806056118 0.343342878 YOL031C -- unknown -- weak similarity to Yarrowia lipolytica Sls1 protein precursor YOL112W MSB4 0.8 16 1.9 0.4819 0.193633623 iYOL113W 0.557522124 0.191588785 0.374756328 MSB4 -- unknown -- Multicopy suppressor of bud emergence mutants YOL148C SPT20 0.8 16 1.9 0.4819 0.219439729 iYOL148C 0.047715226 0.826462602 0.195500325 "SPT20 -- chromatin structure -- Component of nucleosomal histone acetyltransferase (Spt-Ada-Gcn5-Acetyltransferase or SAGA) complex, member of TBP class of SPT proteins" YOR338W YOR338W 0.8 14 1.9 0.4819 0.725679518 iYOR337W 0.722923485 0.341020266 0.076083159 YOR338W -- unknown -- unknown function YDL019C YDL019C 0.7 14 1.9 0.4819 0.416036207 iYDL019C 0.683729 0.333812099 0.919389888 YDL019C -- unknown -- similarity to Osh1p YDR093W YDR093W 0.7 12 1.9 0.4819 0.399085449 iYDR092W 0.340248285 0.314212053 0.220214568 YDR093W -- unknown -- Member of Drs2p family of P-type ATPase superfamily YJL054W TIM54 0.7 14 1.9 0.4819 0.422154738 iYJL055W 0.488871048 0.597605746 0.239847303 "TIM54 -- mitochondrial protein targeting -- Essential mitochondrial inner membrane import of mitochondrial inner membrane proteins, part of translocation channel" YLR105C SEN2 0.7 13 1.9 0.4819 0.889811753 iYLR105C 0.845035073 0.383983242 0.732031943 "SEN2 -- tRNA splicing -- tRNA splicing endonuclease, beta subunit, has active site for 5' splice site cleavage" YLR211C YLR211C 0.7 12 1.9 0.4819 0.212555332 iYLR211C 0.386413177 0.379329609 0.427760307 YLR211C -- unknown -- unknown function YLR305C STT4 0.7 13 1.9 0.4819 0.467588745 iYLR305C 0.766007841 0.30077729 0.519249513 "STT4 -- signaling, PKC1 pathway -- Phosphatidylinositol-4-kinase" YLR397C AFG2 0.7 13 1.9 0.4819 0.500175917 iYLR397C 0.885046347 0.774860335 0.513700321 "AFG2 -- unknown -- AAA family of ATPases, has similarity to mammalian valosin-containing protein (VCP)" YMR119W-A 0.7 13 1.9 0.4819 0.533300281 0.200201072 YMR244C-A 0.7 14 1.9 0.4819 0.36616701 0.086287464 YPL015C HST2 0.7 13 1.9 0.4819 0.338190541 iYPL015C 0.272013806 0.48084597 0.280615533 HST2 -- unknown -- similarity to Sir2p YPL158C YPL158C 0.7 14 1.9 0.4819 0.197411342 iYPL158C 0.67321588 0.166928721 0.529236668 YPL158C -- unknown -- unknown function YAL009W SPO7 0.6 12 1.9 0.4819 0.482313107 iYAL010C 0.365233864 0.550617085 0.510715437 SPO7 -- meiosis -- meiosis YBR145W ADH5 0.6 12 1.9 0.4819 0.319766476 iYBR144C 0.655678305 0.764884278 0.63619466 "ADH5 -- glycolysis -- Alcohol dehydrogenase, zinc-dependent, also called formaldehyde dehydrogenase" YBR176W ECM31 0.6 12 1.9 0.4819 0.925350771 iYBR175W 0.639116668 0.97157245 0.863035772 ECM31 -- cell wall biogenesis -- Putative ketopantoate hydroxymethyltransferase (3-methyl-2-oxobutanoate hydroxymethyltransferase) required for coenzyme A synthesis YGR062C COX18 0.6 11 1.9 0.4819 0.457588241 iYGR062C 0.398258128 0.69881202 0.515405114 COX18 -- respiration -- activity of mitochondrial cytochrome oxidase YJR099W YUH1 0.6 12 1.9 0.4819 0.142753871 iYJR098C 0.245683753 0.346923259 0.306145251 "YUH1 -- protein degradation, ubiquitin-mediated -- Ubiquitin-specific protease" YKL018W YKL018W 0.6 11 1.9 0.4819 0.631722807 iYKL019W 0.141899328 0.810295291 0.039880761 YKL018W -- unknown -- unknown function YKL027W YKL027W 0.6 11 1.9 0.4819 0.5653019 iYKL028W 0.634936053 0.608453658 0.407598613 YKL027W -- unknown -- similarity to E. coli molybdopterin-converting factor YKR010C TOF2 0.6 11 1.9 0.4819 0.404925033 iYKR010C 0.694558645 0.560861499 0.741218176 TOF2 -- DNA replication (putative) -- interacts with DNA topoisomerase I YGR284C YGR284C 3.4 67 1.8 0.4649 1 0.943936635 iYGR284C 0.611544336 0.842784545 0.412529928 YGR284C -- unknown -- similarity to mouse Surf-4 protein YER169W RPH1 0.8 16 1.8 0.4649 1 0.617762436 iYER168C 0.941527414 0.384386078 0.062031137 "RPH1 -- DNA repair -- DNA damage-responsive repressor of PHR1, has two C2H2-type zinc finger domains" YJR132W NMD5 0.8 16 1.8 0.4649 1 0.684075057 iYJR131W 0.929675008 0.569038337 0.358053809 NMD5 -- unknown -- Member of karyopherin-beta familyinvolved in nuclear transport YLR103C CDC45 0.7 13 1.8 0.4649 1 0.870188304 iYLR103C 0.976071294 0.590800625 0.71124718 CDC45 -- DNA replication -- initiation of chromosomal DNA replication YMR014W YMR014W 0.7 14 1.8 0.4649 1 0.963966986 iYMR013C-0 iYMR013C-1 0.987984505 0.987123058 0.29202666 0.107891179 0.264872871 "YMR014W -- unknown -- unknown function, has possible coiled-coil domain" YDR441C APT2 1.8 37 1.8 0.4649 0.736152424 iYDR441C 0.600396592 0.857384851 0.441601689 "APT2 -- purine metabolism -- Adenine phosphoribosyltransferase (APRT), may be a heterodimer with Apt1p" YCR017C YCR017C 1.7 34 1.8 0.4649 0.599501069 iYCR017C 0.326287596 0.334206848 0.613196906 YCR017C -- unknown -- sensitivity to certain drugs YGL087C MMS2 1.7 35 1.8 0.4649 0.877965446 iYGL087C 0.474160086 0.578212291 0.267241379 "MMS2 -- DNA repair, postreplication -- Ubiquitin-conjugating enzyme variant (UEV) resistance to DNA damaging agents" YML117W-A 1.7 34 1.8 0.4649 0.491160884 0.374381484 YIL124W AYR1 1.6 33 1.8 0.4649 0.485999834 iYIL125W 0.568166793 0.938210857 0.39751853 AYR1 -- lipid metabolism -- 1-Acyl dihydroxyacetone phosphate reductase YAR027W YAR027W 1.3 28 1.8 0.4649 0.684549498 iYAR023C itL(CAA)A 0.228411829 0.70893782 0.248010284 0.721303541 0.789725974 "YAR027W -- unknown -- strong similarity to subtelomerically-encoded proteins such as Cos5p, Ybr302p, Cos3p, Cos1p, Cos4p, Cos8p, Cos6p, Cos9p, and Ycr007p" YDR372C YDR372C 1.3 27 1.8 0.4649 0.361437217 iYDR372C 0.447827723 0.87773344 0.633258137 YDR372C -- unknown -- unknown function YDR394W RPT3 1.2 26 1.8 0.4649 0.878427399 iYDR393W 0.844271812 0.961304895 0.647347077 "RPT3 -- protein degradation -- ATPase component of 26S proteasome complex, member of AAA family of ATPases" YJR125C ENT3 1.2 26 1.8 0.4649 0.328854013 iYJR125C 0.183003203 0.488347965 0.154000699 ENT3 -- endocytosis (putative) -- unknown function YGL091C NBP35 1.1 24 1.8 0.4649 0.72124942 iYGL091C 0.440600717 0.880526736 0.32334308 "NBP35 -- unknown -- Putative nucleotide-binding protein, has similarity to bacterial partitioning ATPases" YGR097W ASK10 1.1 23 1.8 0.4649 0.49596644 iYGR096W 0.346554911 0.531257562 0.506281621 ASK10 -- stress response -- Potential transcription factor involved in Skn7p-mediated two-component regulatory system YGR102C YGR102C 1.1 23 1.8 0.4649 0.365083661 iYGR102C 0.388843515 0.598244214 0.620281131 YGR102C -- unknown -- unknown function YMR220W ERG8 1.1 23 1.8 0.4649 0.211883325 iYMR219W 0.13648405 0.324980048 0.02956816 "ERG8 -- sterol metabolism -- Phosphomevalonate kinase, converts mevalonate-5-phosphate to mevalonate pyrophosphate, involved in isoprene and ergosterol biosynthesis pathways" YOR202W HIS3 1.1 22 1.8 0.4649 0.378617582 iYOR201C 0.309070519 0.433280128 0.095710355 "HIS3 -- histidine biosynthesis -- Imidazoleglycerolphosphate (IGP) dehydratase, seventh step in histidine biosynthesis pathway" YDL065C PEX19 1 22 1.8 0.4649 0.397756833 iYDL065C 0.641216796 0.290527404 0.547326417 PEX19 -- peroxisome biogenesis -- Farnesylated peroxisome biogenesis (peroxin) YDR228C PCF11 1 22 1.8 0.4649 0.387447322 iYDR228C 0.397937963 0.198164405 0.627154444 "PCF11 -- mRNA 3'-end processing -- Component of pre-mRNA cleavage and polyadenylation factor I, interacts with Rna14p and Rna15p" YER017C AFG3 1 22 1.8 0.4649 0.589274141 iYER017C 0.604433494 0.717398244 0.734832202 "AFG3 -- protein degradation -- Mitochondrial protein involved with Yta12p in proteolytic and chaperonin activities at the inner membrane, responsible for assembly of respiratory chain complexes, member of AAA family of ATPases" YIL010W DOT5 1 20 1.8 0.4649 0.540761944 iYIL011W 0.690847644 0.707348552 0.505283536 "DOT5 -- transcription -- Nuclear thiol peroxidase, involved in telomeric silencing" YJR126C YJR126C 1 21 1.8 0.4649 0.314225823 iYJR126C 0.490144957 0.425748165 0.362215091 "YJR126C -- unknown -- unknown function, has similarity to transferrin receptor" YKR028W SAP190 1 21 1.8 0.4649 0.165764756 iYKR027W 0.742632497 0.476754711 0.748648867 SAP190 -- cell cycle -- associates with and contributes to function of protein phosphatase Sit4p YKR087C YKR087C 1 21 1.8 0.4649 0.462508168 iYKR087C 0.632661598 0.778267399 0.724530128 YKR087C -- unknown -- putative zinc-binding motif of neutral zinc metallopeptidases YMR135C YMR135C 1 20 1.8 0.4649 0.498088567 0.571109338 YMR135C -- unknown -- unknown function YNL125C ESBP6 1 21 1.8 0.4649 0.198149066 iYNL125C 0.062573782 0.319881202 0.131901588 "ESBP6 -- unknown -- similarity to mammalian monocarboxylate transporters MCT1 and MCT2, member of monocarboxylate porter (MCP) family of major facilitator superfamily (MFS)" YNL238W KEX2 1 21 1.8 0.4649 0.212920614 iYNL239W 0.675707725 0.505631655 0.747798897 "KEX2 -- secretion -- Endoprotease (yscF) of late Golgi compartment involved in processing of alpha-factor, cleaves C-terminal to a dibasic sequence" YNR074C YNR074C 1 20 1.8 0.4649 0.40766059 iYNR074C 0.326374293 0.298420478 0.224415205 YNR074C -- unknown -- similarity to various reductases YPL002C SNF8 1 20 1.8 0.4649 0.239344113 iYPL002C 0.489405214 0.212487327 0.509092405 SNF8 -- glucose derepression -- glucose derepression YAR014C YAR014C 0.9 18 1.8 0.4649 0.491812553 iYAR014C 0.312322622 0.503992902 0.326519916 "YAR014C -- unknown -- unknown function, contains a predicted SH3 domain" YBR241C YBR241C 0.9 18 1.8 0.4649 0.158389668 iYBR241C 0.64440667 0.432881085 0.666290232 YBR241C -- unknown -- Member of hexose transporter family of major facilitator superfamily (MFS) YCL001W RER1 0.9 18 1.8 0.4649 0.741521423 iYCL002C 0.194936938 0.475329503 0.418826627 RER1 -- secretion; protein targeting -- retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment YDL102W CDC2 0.9 17 1.8 0.4649 0.505534737 iYDL103C 0.177942149 0.431260425 0.120674357 CDC2 -- DNA replication -- DNA polymerase delta large subunit YJL180C ATP12 0.9 19 1.8 0.4649 0.835710853 iYJL180C 0.190133943 0.68957115 0.069231414 ATP12 -- ATP synthesis -- F1-ATP synthase assembly protein YKL059C YKL059C 0.9 20 1.8 0.4649 0.467763945 iYKL059C 0.243142617 0.258862391 0.415941317 YKL059C -- unknown -- similarity to members of chaperonin-containing T-complex YLR016C YLR016C 0.9 19 1.8 0.4649 0.44559649 iYLR016C 0.436914802 0.55795877 0.448410347 YLR016C -- unknown -- unknown function YNL161W CBK1 0.9 18 1.8 0.4649 0.307554866 iYNL162W 0.737199441 0.332927225 0.447930951 CBK1 -- cell wall biosynthesis (putative) -- Serine/threonine protein kinase required for sporulation YOR097C YOR097C 0.9 19 1.8 0.4649 0.415494749 iYOR097C 0.608704363 0.604868316 0.585714286 YOR097C -- unknown -- unknown function YPL089C RLM1 0.9 19 1.8 0.4649 0.745044124 iYPL089C 0.415662771 0.161277051 0.17450854 "RLM1 -- cell wall organization -- Transcription factor of MADS (Mcm1p, Agamous, Deficiens, SRF) box family" YPL203W PKA3 0.9 17 1.8 0.4649 0.28724174 iYPL204W 0.24832386 0.328873585 0.4094539 "PKA3 -- signaling, nutrient control of cell growth -- cAMP-dependent protein kinase 2, catalytic chain of protein kinase A" YDR511W YDR511W 0.8 15 1.8 0.4649 0.34058443 iYDR510W 0.299329438 0.790029846 0.345038435 YDR511W -- unknown -- unknown function YGR125W YGR125W 0.8 16 1.8 0.4649 0.323402809 iYGR124W 0.463908517 0.879567637 0.560574621 YGR125W -- unknown -- Member of sulfate permease family of membrane transporters YHL029C YHL029C 0.8 15 1.8 0.4649 0.560495217 iYHL029C 0.08757653 0.756185156 0.056707268 YHL029C -- unknown -- unknown function YJL104W YJL104W 0.8 16 1.8 0.4649 0.855396407 iYJL105W 0.49681229 0.933001398 0.647172703 YJL104W -- unknown -- unknown function YLL042C APG10 0.8 15 1.8 0.4649 0.794083951 iYLL042C 0.725918731 0.814041906 0.358914123 APG10 -- autophagy -- Protein-conjugating enzyme essential for autophagy YML051W GAL80 0.8 16 1.8 0.4649 0.551595846 iYML052W 0.037382426 0.721785465 0.094725284 "GAL80 -- galactose regulation -- Negative regulator for expression of galactose-induced genes, forms a 1" YMR152W YIM1 0.8 16 1.8 0.4649 0.455781458 iYMR151W 0.093433518 0.717303143 0.085769981 "YIM1 -- protein processing -- Mitochondrial inner membrane protease, has sequence similarity to E. coli leader peptidase" YNL165W YNL165W 0.8 15 1.8 0.4649 0.865084446 iYNL166C 0.892326866 0.948261858 0.550596197 YNL165W -- unknown -- unknown function YOR148C SPP2 0.8 15 1.8 0.4649 0.034096512 iYOR148C 0.247713166 0.06767489 0.215961692 "SPP2 -- mRNA splicing -- pre-mRNA processing, high-copy suppressor of temperature-sensitive prp2 mutations" YOR213C SAS5 0.8 16 1.8 0.4649 0.572866316 iYOR213C 0.240680031 0.726635514 0.468992903 SAS5 -- silencing -- silencing at telomeres and the silent mating type loci YPL214C THI6 0.8 17 1.8 0.4649 0.388190134 iYPL214C 0.476888578 0.57402872 0.502021857 "THI6 -- thiamine biosynthesis -- Bifunctional thiamine-phosphate pyrophosphorylase (TMP-PPase)/hydroxyethylthiazole kinase (Th-kinase), enzyme of thiamine biosynthetic pathway" YPR057W BRR1 0.8 16 1.8 0.4649 0.793518346 iYPR056W 0.909880653 0.770105671 0.34128232 BRR1 -- mRNA splicing -- snRNP biogenesis YBR163W DEM1 0.7 14 1.8 0.4649 0.267028266 iYBR162W-A 0.450190793 0.739606832 0.800676764 "DEM1 -- cell morphology (putative) -- unknown function, has a role in multiple processes including cell cycle, stress resistance, mitochondrial morphology and respiration" YDL058W USO1 0.7 15 1.8 0.4649 0.52765905 iYDL059C 0.27118792 0.426067638 0.575179569 "USO1 -- secretion -- Coiled-coil similarity to mammalian integrin, required for protein transport from ER to Golgi" YDL207W GLE1 0.7 15 1.8 0.4649 0.707382224 iYDL208W 0.677687341 0.4743083 GLE1 -- mRNA export -- RNA export mediator YGL050W YGL050W 0.7 13 1.8 0.4649 0.612947305 iYGL051W itR(UCU)G1 0.112004829 0.402090631 0.645665485 0.502196688 0.160115304 YGL050W -- unknown -- unknown function YGL094C PAN2 0.7 15 1.8 0.4649 0.460644313 iYGL094C 0.42421502 0.703315318 0.552585604 PAN2 -- mRNA processing -- Component of Pab1p-stimulated poly(A) ribonuclease YGL164C YGL164C 0.7 14 1.8 0.4649 0.492967034 iYGL164C 0.549042406 0.008203379 0.406711301 YGL164C -- unknown -- unknown function YGR228W YGR228W 0.7 14 1.8 0.4649 0.234332982 iYGR227W 0.789102557 0.148374545 0.284940601 YGR228W -- unknown -- unknown function YIL068C SEC6 0.7 13 1.8 0.4649 0.809003493 iYIL068C 0.387571203 0.705905826 0.185366678 SEC6 -- secretion -- Component of exocyst complex required for exocytosis YIR008C PRI1 0.7 13 1.8 0.4649 0.49292493 iYIR008C 0.637448366 0.800837899 0.369766879 PRI1 -- DNA replication -- DNA primase small subunit (DNA polymerase alpha 48 kDa subunit) involved in the synthesis of RNA primers for Okazaki fragments YJR080C YJR080C 0.7 13 1.8 0.4649 0.558792116 iYJR080C 0.18497226 0.918435754 0.383447044 YJR080C -- unknown -- unknown function YJR084W YJR084W 0.7 15 1.8 0.4649 0.39098964 iYJR083C 0.350194734 0.870982677 0.070143256 YJR084W -- unknown -- unknown function YJR159W SOR1 0.7 13 1.8 0.4649 0.369914884 iYJR158W-0 iYJR158W-1 0.279705834 0.295900033 0.536871508 0.284441242 0.424102155 "SOR1 -- sorbitol metabolism -- Sorbitol dehydrogenase, converts L-sorbitol and NAD(+) to L-sorbose and NADH" YKL057C NUP120 0.7 13 1.8 0.4649 0.461546356 iYKL057C 0.653830694 0.762442526 0.455981751 NUP120 -- nuclear protein targeting -- Nuclear pore protein YKL130C SHE2 0.7 13 1.8 0.4649 0.432874354 iYKL130C 0.547513104 0.97905253 0.583041468 SHE2 -- cell polarity -- mother cell-specific expression of HO YKL168C KKQ8 0.7 13 1.8 0.4649 0.599551049 iYKL168C 0.395793418 0.752255881 0.661794525 KKQ8 -- unknown -- Serine/threonine protein kinase of unknown function YLR427W YLR427W 0.7 13 1.8 0.4649 0.102492057 iYLR426W 0.25489975 0.228765024 0.598128579 YLR427W -- unknown -- unknown function YNL094W YNL094W 0.7 15 1.8 0.4649 0.601616644 iYNL095C 0.160741191 0.680393112 0.316759777 YNL094W -- unknown -- unknown function YNL164C YNL164C 0.7 14 1.8 0.4649 0.212252231 iYNL164C 0.438856052 0.60726257 0.280485674 YNL164C -- unknown -- unknown function YPL057C SUR1 0.7 14 1.8 0.4649 0.592643812 iYPL057C 0.521112354 0.572226656 0.174626381 SUR1 -- sphingolipid metabolism -- the synthesis of mannosylated sphingolipids YBL069W AST1 0.6 11 1.8 0.4649 0.864240752 0.84649512 AST1 -- plasma membrane protein targeting -- targeting of plasma membrane H(+)-ATPase Pma1p YBR141C YBR141C 0.6 11 1.8 0.4649 0.379466835 iYBR141C 0.169228227 0.762264457 0.030168589 YBR141C -- unknown -- unknown function YDL001W YDL001W 0.6 12 1.8 0.4649 0.082333699 iYDL002C 0.59180924 0.116309292 0.447608292 YDL001W -- unknown -- similarity to Yfr048p YDR107C YDR107C 0.6 12 1.8 0.4649 0.176836044 iYDR107C 0.339912062 0.447631325 0.171820405 YDR107C -- unknown -- strong similarity to Emp70p YHR154W ESC4 0.6 12 1.8 0.4649 0.8589754 iYHR153C 0.124452672 0.540027813 0.141179453 ESC4 -- silencing -- chromatin silencing YHR202W YHR202W 0.6 11 1.8 0.4649 0.682771927 iYHR201C 0.413266282 0.773797921 0.429337232 YHR202W -- unknown -- unknown function YOR188W MSB1 0.6 10 1.8 0.4649 0.159180007 iYOR187W 0.384199306 0.449063087 0.263482781 MSB1 -- polarized growth -- may play a role in polarity establishment and bud formation YPL208W YPL208W 0.6 12 1.8 0.4649 0.337604526 iYPL209C 0.588736813 0.348671772 0.405098008 YPL208W -- unknown -- unknown function YEL066W HPA3 0.4 10 1.8 0.4649 0.710016187 0.735903848 HPA3 -- chromatin structure -- Histone and other protein acetyltransferase YFR038W YFR038W 0.4 9 1.8 0.4649 0.423896128 iYFR037C 0.176896704 0.543764785 0.15412504 YFR038W -- unknown -- Member of Snf2/Rad54 subfamily of NTP-dependent DNA helicases YJL218W YJL218W 0.4 10 1.8 0.4649 0.170692768 iYJL219W 0.510049492 0.388906624 0.398529909 YJL218W -- unknown -- similarity to E. coli galactoside O-acetyltransferase YOR092W ECM3 0.4 11 1.8 0.4649 0.189886506 iYOR091W 0.683655727 0.359696728 0.777471815 ECM3 -- cell wall biogenesis -- Protein possibly involved in cell wall structure or biosynthesis YOR071C YOR071C 0.3 8 1.8 0.4649 0.268385934 iYOR071C 0.720590196 0.606598371 0.729322298 YOR071C -- transport -- Probable low affinity thiamine transporter YPL095C YPL095C 0.9 19 1.7 0.4491 1 0.703586411 iYPL095C 0.943159177 0.743495611 0.717556607 YPL095C -- unknown -- similarity to Ybr177p YCL037C SRO9 0.7 15 1.7 0.4491 1 0.926198309 iYCL037C 0.960346205 0.051674484 0.151642208 "SRO9 -- cytoskeleton -- associated with ribosomes, has a potential role in translational accuracy, member of a subfamily of La motif proteins" YDR448W ADA2 0.7 14 1.7 0.4491 1 0.984446701 iYDR447C 0.981874847 0.956708902 0.633419272 ADA2 -- chromatin structure -- Component of two nucleosomal histone acetyltransferase complexes YFL024C EPL1 0.7 16 1.7 0.4491 1 0.518354192 iYFL024C 0.922211429 0.430965682 0.001949318 "EPL1 -- unknown -- Member of NuA4 histone acetyltransferase complex, has similarity to Drosophila E(Pc) (Enhancer of Polycomb) protein" YNL326C YNL326C 0.6 12 1.7 0.4491 1 0.982782833 iYNL326C 0.52948983 0.066387367 0.286062378 YNL326C -- unknown -- similarity to Akr1p and Ydr126p YGL207W SPT16 2 44 1.7 0.4491 0.544662889 iYGL208W 0.16019464 0.536570679 0.073180637 SPT16 -- chromatin structure -- General chromatin factor required for adequate expression of CLN and other genes YIL129C TAO3 2 43 1.7 0.4491 0.882347947 iYIL129C 0.148920465 0.840383081 0.144221021 TAO3 -- transcription (putative) -- Transcriptional Activator of OCH1 YBR287W YBR287W 1.2 26 1.7 0.4491 0.169309323 iYBR286W 0.799418976 0.439337614 0.804418454 YBR287W -- unknown -- unknown function YLR106C YLR106C 1.2 26 1.7 0.4491 0.548647597 iYLR106C 0.726183777 0.418196329 0.5132723 YLR106C -- unknown -- weak similarity near the N-terminus to Dyn1p and with weak similarity in the C-terminus to End3p YOR185C GSP2 1.2 27 1.7 0.4491 0.478341228 iYOR185C 0.416727269 0.640303272 0.492202729 "GSP2 -- nuclear organization -- Ran, a GTP-binding protein member of ras superfamily involved in trafficking through nuclear pores" YBR201W DER1 1.1 23 1.7 0.4491 0.625204182 iYBR200W 0.264559335 0.495553845 0.401793796 "DER1 -- protein degradation, ER -- degradation of misfolded soluble proteins in the endoplasmic reticulum" YDR349C YPS7 1.1 25 1.7 0.4491 0.409502995 iYDR349C iYDRWdelta26 0.657790708 0.869900571 0.878277003 0.880760554 0.802090826 "YPS7 -- protein degradation -- Yapsin 7, GPI-anchored aspartyl protease" YHR087W YHR087W 1.1 24 1.7 0.4491 0.816596024 iYHR086W 0.078747157 0.843274755 0.285012518 YHR087W -- unknown -- unknown function YIL138C TPM2 1.1 24 1.7 0.4491 0.053258441 iYIL138C 0.448984533 0.075984973 0.452044025 "TPM2 -- cytoskeleton -- Tropomyosin isoform 2, coiled-coil protein" YLR093C NYV1 1.1 23 1.7 0.4491 0.456549517 iYLR093C 0.617577525 0.833867348 0.492619182 NYV1 -- vacuolar protein targeting -- Synaptobrevin (v-SNARE) homolog involved in vacuolar vesicle fusion YDR079W PET100 1 20 1.7 0.4491 0.572166112 iYDR078C 0.458068288 0.415042235 0.247181766 PET100 -- respiration -- assembly of cytochrome c oxidase YGL228W SHE10 1 22 1.7 0.4491 0.775938754 iYGL229C 0.081517807 0.950876327 0.109286009 SHE10 -- unknown -- causes lethality when overexpressed YLR461W PAU4 1 22 1.7 0.4491 0.936289359 iYLR460C-0 iYLR460C-1 0.720026135 0.941672582 0.745825603 0.798651722 0.641580208 PAU4 -- unknown -- Member of seripauperin (PAU) family YBL015W ACH1 0.9 20 1.7 0.4491 0.597637022 iYBL016W 0.653642621 0.917802694 0.847396925 "ACH1 -- acetyl-CoA metabolism -- Acetyl-CoA hydrolase, hydrolyzes longer acyl CoA chains slowly" YEL039C CYC7 0.9 19 1.7 0.4491 0.398399216 iYEL039C 0.41910428 0.499349253 0.432215234 "CYC7 -- respiration -- Cytochrome-c isoform 2, predominant isoform during anaerobic growth" YGL248W PDE1 0.9 20 1.7 0.4491 0.542762815 iYGL249W 0.114500032 0.964137519 0.360136452 "PDE1 -- purine metabolism -- 3',5'-Cyclic-nucleotide phosphodiesterase, low affinity" YKL066W YKL066W 0.9 19 1.7 0.4491 0.74734008 0.834802382 YKL066W -- unknown -- unknown function YMR009W YMR009W 0.9 19 1.7 0.4491 0.669828764 iYMR008C 0.482848742 0.930167598 0.195133742 YMR009W -- unknown -- similarity to MMSAB operon regulatory protein YMR285C YMR285C 0.9 19 1.7 0.4491 0.150333022 iYMR285C 0.653610973 0.697104138 0.529992594 YMR285C -- unknown -- unknown function YOR245C YOR245C 0.9 18 1.7 0.4491 0.12678133 iYOR245C 0.20115789 0.390822027 0.18488344 YOR245C -- unknown -- unknown function YAL055W PEX22 0.8 16 1.7 0.4491 0.400850017 iYAL056W 0.529770689 0.362955205 0.348684211 PEX22 -- unknown -- unknown function YBR022W YBR022W 0.8 18 1.7 0.4491 0.324833217 iYBR021W 0.428418186 0.621037348 0.277544639 "YBR022W -- unknown -- Adenosine diphosphate-ribose 1""-phosphate (Appr-1""-p)-processing enzyme" YDL006W PTC1 0.8 16 1.7 0.4491 0.799215211 iYDL007W 0.592925368 0.304866258 0.325185998 "PTC1 -- tRNA splicing -- Protein serine/threonine phosphatase of PP2C family, involved in the dephosphorylation of multiple MAP kinases and involved in tRNA splicing" YDL231C YDL231C 0.8 16 1.7 0.4491 0.52979593 iYDL231C 0.334223353 0.469114126 0.305347167 "YDL231C -- unknown -- unknown function, has a putative zinc finger domain" YDR005C MAF1 0.8 17 1.7 0.4491 0.5648373 iYDR005C 0.550582036 0.798096314 0.582024594 MAF1 -- protein targeting (putative) -- sorting of Mod5p YDR146C SWI5 0.8 17 1.7 0.4491 0.252062233 iYDR146C 0.523000305 0.27296165 0.842679944 "SWI5 -- cell cycle -- Transcription factor that controls cell cycle-specific transcription of HO, has three tandem C2H2-type zinc fingers" YDR293C SSD1 0.8 18 1.7 0.4491 0.560363725 iYDR293C 0.134092552 0.731237817 0.273203352 "SSD1 -- drug resistance -- Single-copy suppressor of many different mutations, associated with cytoplasmic RNA" YDR296W MHR1 0.8 18 1.7 0.4491 0.329283574 iYDR295C 0.269601437 0.533032185 0.226022425 "MHR1 -- recombination, mitochondrial -- repair, recombination and maintenance of mitochondrial DNAalso copurifies with RNA polymerase II" YGL129C YGL129C 0.8 17 1.7 0.4491 0.373076949 iYGL129C 0.575050123 0.41452514 0.194573025 "YGL129C -- unknown -- Putative mitochondrial carrier protein, required for respiration and mitochondrial maintenance" YHL047C TAF1 0.8 19 1.7 0.4491 0.498440806 iYHL047C-0 iYHL047C-1 0.303141904 0.45790837 0.472386273 0.13585123 "TAF1 -- unknown -- Triacetylfusarinine C transporter, member of yeast-specific putative multidrug-resistance family of major facilitator superfamily (MFS)" YLR095C IOC2 0.8 18 1.7 0.4491 0.270038008 iYLR095C 0.396597729 0.322388376 0.365012754 IOC2 -- unknown -- unknown function YOR034C AKR2 0.8 16 1.7 0.4491 0.477929581 iYOR034C 0.678205776 0.610860458 0.692801622 AKR2 -- endocytosis of Ste3p -- constitutive endocytosis of Ste3p YPL034W YPL034W 0.8 17 1.7 0.4491 0.455571507 0.368794892 YPL034W -- unknown -- unknown function YBR058C UBP14 0.7 16 1.7 0.4491 0.404836231 iYBR058C 0.546017094 0.677236198 0.507815018 "UBP14 -- protein degradation, ubiquitin-mediated -- Ubiquitin-specific protease, ubiquitin C-terminal hydrolase" YDL080C THI3 0.7 16 1.7 0.4491 0.281230872 iYDL080C 0.645596649 0.338289963 0.722352182 THI3 -- thiamine metabolism -- Major alpha-ketoisocaproate carboxylase YDL108W KIN28 0.7 15 1.7 0.4491 0.352074617 iYDL109C 0.522053016 0.49707967 0.547595841 "KIN28 -- transcription -- Cyclin-dependent serine/threonine protein kinase, component of transcription initiation factor TFIIH, phosphorylates C-terminal domain (CTD) of Rpo21p" YDL141W BPL1 0.7 15 1.7 0.4491 0.484925351 iYDL142C 0.218272513 0.849255328 0.388172736 "BPL1 -- protein processing -- Biotin protein ligase, catalyzes covalent attachment of biotin to biotin domain of acceptor proteins in an ATP-dependent reaction" YDR180W SCC2 0.7 14 1.7 0.4491 0.53979462 iYDR179W-A 0.736556785 0.925203653 0.845411014 "SCC2 -- mitosis, sister chromatid cohesion -- Cohesin, mitotic sister chromatid cohesion" YDR435C PPM1 0.7 14 1.7 0.4491 0.865813552 iYDR435C 0.217921256 0.984517159 0.39377494 "PPM1 -- unknown -- Carboxy methyltransferase for protein phosphatase 2A catalytic subunit, has similarity to human LCMT" YEL052W AFG1 0.7 14 1.7 0.4491 0.439977815 iYEL053C 0.846048718 0.297704271 0.776818502 AFG1 -- unknown -- weak similarity to members of AAA family of ATPases YFL004W PHM1 0.7 15 1.7 0.4491 0.76584907 iYFL005W 0.530482519 0.871985158 0.626414598 PHM1 -- unknown -- Putative polyphosphate synthetase YGL226W YGL226W 0.7 15 1.7 0.4491 0.083469225 iYGL226C-A 0.329992862 0.317251462 0.098894894 YGL226W -- unknown -- weak similarity to Neurospora cytochrome-c oxidase chain V precursor YHR207C YHR207C 0.7 14 1.7 0.4491 0.640283756 iYHR207C 0.331297962 0.874969301 0.723884811 "YHR207C -- unknown -- unknown function, has two C2H2-type zinc fingers" YIL022W TIM44 0.7 13 1.7 0.4491 0.511033002 iYIL023C 0.600933543 0.557969226 0.521628093 TIM44 -- mitochondrial protein targeting -- Mitochondrial inner membrane protein required in transport across the inner membrane YLL010C PSR1 0.7 15 1.7 0.4491 0.292235436 iYLL010C 0.426871591 0.449074074 0.632189583 PSR1 -- unknown -- unknown function YLR021W YLR021W 0.7 14 1.7 0.4491 0.141581424 iYLR020C 0.316167798 0.216759777 0.184221493 YLR021W -- unknown -- unknown function YNL185C MRPL19 0.7 16 1.7 0.4491 0.563956371 0.631281762 MRPL19 -- protein synthesis -- Mitochondrial ribosomal large subunit YNL258C YNL258C 0.7 16 1.7 0.4491 0.385984972 iYNL258C 0.718866949 0.554972977 0.85698324 YNL258C -- unknown -- Essential unknown function YNL264C PDR17 0.7 15 1.7 0.4491 0.200305262 iYNL264C 0.277824415 0.531338227 0.06026426 PDR17 -- drug resistance -- lipid biosynthesis and in resistance to drugs and to NaCl YOR316C COT1 0.7 15 1.7 0.4491 0.350184911 iYOR316C-0 iYOR316C-1 0.705008664 0.917170267 0.390461216 0.429768555 0.557940942 COT1 -- Co2+ ion homeostasis -- cobalt accumulation YPL047W YPL047W 0.7 15 1.7 0.4491 0.857615254 iYPL048W 0.263071614 0.594785575 0.416754018 YPL047W -- unknown -- unknown function YPL134C YPL134C 0.7 15 1.7 0.4491 0.423921742 iYPL134C 0.698123436 0.343794714 0.503756115 "YPL134C -- unknown -- similarity to mitochondrial ADP/ATP carrier proteins, member of mitochondrial carrier (MCF) family of membrane transporters" YPR021C YPR021C 0.7 16 1.7 0.4491 0.400357625 iYPR021C 0.425563237 0.381963301 0.685794094 YPR021C -- unknown -- Member of mitochondrial carrier (MCF) family of membrane transporters YPR034W ARP7 0.7 15 1.7 0.4491 0.23187425 iYPR033C 0.134331049 0.147904483 0.068460462 ARP7 -- cytoskeleton (putative) -- Component of SWI-SNF global transcription activator complex and RSC chromatin remodeling complexacts to assist gene-specific activators through chromatin remodeling YPR199C ARR1 0.7 14 1.7 0.4491 0.458827926 iYPR199C 0.566696436 0.455466879 0.183930988 "ARR1 -- transcription -- Transcription factor of basic leucine zipper (bZIP) family involved in arsenic resistance, member of a fungal-specific family of bZIP proteins" YAL013W DEP1 0.6 13 1.7 0.4491 0.032705756 iYAL014C 0.324781648 0.211730583 0.072530864 DEP1 -- phospholipid metabolism -- Regulator of phospholipid metabolism YAL058W CNE1 0.6 13 1.7 0.4491 0.729598152 iYAL059W 0.586682069 0.541652585 0.482131254 "CNE1 -- secretion -- similarity to mammalian calnexin and calreticulin, may be involved in a quality control process for secretory pathway proteins" YDL167C NRP1 0.6 11 1.7 0.4491 0.483620761 iYDL167C 0.318980116 0.6207502 0.445969673 NRP1 -- unknown -- Asparagine-rich one RNA recognition (RRM) domain YDR075W PPH3 0.6 13 1.7 0.4491 0.634174453 iYDR074W 0.383644032 0.771672575 0.27337259 "PPH3 -- cell cycle -- Protein serine/threonine phosphatase, member of PPP family of protein phosphatases and related to PP2A phosphatases" YDR108W GSG1 0.6 12 1.7 0.4491 0.443569371 iYDR107C 0.339912062 0.469668807 0.171820405 GSG1 -- meiosis -- High molecular weight subunit of Transport Protein Particle (TRAPP) complex that is involved in the vesicular transport from the endoplasmic reticulum to the Golgi YGL243W TAD1 0.6 12 1.7 0.4491 0.280883159 iYGL244W 0.101912323 0.630518853 0.022545873 TAD1 -- tRNA processing -- tRNA[Ala]-specific adenosine deaminase YGR049W SCM4 0.6 12 1.7 0.4491 0.27515266 iYGR048W 0.518271676 0.409437947 0.56675002 SCM4 -- cell cycle -- suppresses temperature-sensitive allele of CDC4 when overexpressed YJR031C GEA1 0.6 13 1.7 0.4491 0.418140567 iYJR031C 0.392373739 0.380438286 0.170159194 GEA1 -- secretion -- Component of complex with guanine-nucleotide-exchange activity for ARF YKL006C-A 0.6 13 1.7 0.4491 0.564046749 iYKL006C-A 0.979317633 0.246027265 0.713733235 YKL215C YKL215C 0.6 14 1.7 0.4491 0.376568944 iYKL215C 0.156775331 0.496007098 0.219017975 YKL215C -- unknown -- similarity to Pseudomonas hydantoinases hyuA-hyuB YLR200W YKE2 0.6 13 1.7 0.4491 0.548402939 iYLR199C 0.613079711 0.688427773 0.518884226 "YKE2 -- cytoskeleton -- Prefoldin subunit 6, component of Gim protein complex that promotes formation of functional alpha- and gamma-tubulin, and actin" YLR239C YLR239C 0.6 13 1.7 0.4491 0.140822011 iYLR239C 0.409548472 0.573606518 0.395498911 YLR239C -- unknown -- similarity to E. coli LipB protein which is involved in lipoate biosynthesis YMR035W IMP2 0.6 12 1.7 0.4491 0.880892465 iYMR034C 0.588371718 0.649628578 0.811322307 "IMP2 -- protein processing -- Catalytic subunit of mitochondrial inner membrane protease Imp, acts in complex with Imp1p but has different substrate specificity for removal of signal peptides" YOR154W YOR154W 0.6 12 1.7 0.4491 0.388742953 iYOR153W 0.72011955 0.720271349 0.769238487 YOR154W -- unknown -- unknown function YPL007C TFC8 0.6 12 1.7 0.4491 0.772600644 iYPL007C 0.176434339 0.83471668 0.245457722 "TFC8 -- unknown -- RNA Polymerase III transcription initiation factor TFIIIC (tau), 60 kDa subunit" YJL074C SMC3 0.4 11 1.7 0.4491 0.168555814 iYJL074C 0.434114078 0.745020964 0.443923925 "SMC3 -- chromatin structure -- Cohesin, coiled-coil SMC family involved in chromosome condensation and segregation" YJL187C SWE1 0.4 10 1.7 0.4491 0.602304595 iYJL187C 0.299054294 0.503431764 0.365090968 SWE1 -- cell cycle -- Serine/tyrosine dual-specificity protein kinaseable to phosphorylate Cdc28p on tyrosine and inhibit its activity YLR015W YLR015W 0.4 11 1.7 0.4491 0.164809601 iYLR014C 0.334087948 0.576348278 0.137210615 YLR015W -- unknown -- unknown function YPL068C YPL068C 0.4 10 1.7 0.4491 0.136325866 iYPL068C 0.739709245 0.038349984 0.469393811 YPL068C -- unknown -- unknown function YPR006C ICL2 0.4 10 1.7 0.4491 0.201121309 iYPR006C 0.166842575 0.378178228 0.257895585 "ICL2 -- unknown -- Isocitrate lyase, may be nonfunctional" YHL046C YHL046C 1 23 1.6 0.4287 1 0.919336056 iYHL046C 0.940629956 0.608856982 0.389762404 YHL046C -- unknown -- Member of seripauperin (PAU) family YLR389C STE23 0.8 19 1.6 0.4287 1 0.890761858 iYLR389C 0.961941516 0.918534763 0.709795322 STE23 -- mating -- Protease involved in a-factor processinghas similarity to Axl1p and human and Drosophila insulin-degrading enzymes YLR390W ECM19 0.8 18 1.6 0.4287 1 0.980327857 iYLR389C 0.961941516 0.193136472 0.709795322 ECM19 -- cell wall biogenesis -- Protein possibly involved in cell wall structure or biosynthesis YML088W YML088W 0.4 11 1.6 0.4287 1 0.485045286 iYML089C 0.961832185 0.665564249 0.887749783 "YML088W -- unknown -- unknown function, contains an F-box" YCL034W YCL034W 1.8 43 1.6 0.4287 0.186135002 iYCL035C 0.128573789 0.034067086 0.113993711 YCL034W -- unknown -- unknown function YBR008C FLR1 1.7 38 1.6 0.4287 0.441392454 iYBR008C 0.498601639 0.807847245 0.434210526 FLR1 -- fluconazole resistance -- Member of multidrug-resistance 12-spanner family of major facilitator superfamily (MFS-MDR) YLR025W SNF7 1.7 39 1.6 0.4287 0.280962585 iYLR024C 0.183715985 0.301675978 0.404229848 SNF7 -- glucose derepression -- glucose derepression and in sorting in pre-vacuolar endosome YBL057C YBL057C 1.5 36 1.6 0.4287 0.465259918 iYBL057C 0.69810621 0.84012261 0.941739824 YBL057C -- unknown -- unknown function YDL133W YDL133W 1.1 26 1.6 0.4287 0.956571069 iYDL133C-A YDL133C-A 0.993871801 0.926228038 0.744846232 0.373951782 0.310338049 YDL133W -- unknown -- unknown function YDL160C DHH1 1.1 25 1.6 0.4287 0.181693189 iYDL160C 0.403542954 0.280918292 0.308176101 DHH1 -- transcription -- Putative RNA helicase of DEAD/DEAH box family YMR027W HRT2 1.1 25 1.6 0.4287 0.491911109 iYMR026C 0.591602721 0.760070899 0.200032914 "HRT2 -- transposition, Ty3 (putative) -- affects Ty3 transposition" YBR122C MRPL36 1 24 1.6 0.4287 0.513246712 iYBR122C 0.518950126 0.591272082 0.159175397 MRPL36 -- protein synthesis -- Mitochondrial ribosomal large subunit YGR186W TFG1 1 22 1.6 0.4287 0.198361589 iYGR185C 0.353307196 0.311169314 0.483228512 "TFG1 -- transcription -- RNA polymerase II transcription initiation factor TFIIF (factor g), 105 kDa subunit, component of RNA polymerase holoenzyme complex" YLR199C YLR199C 1 23 1.6 0.4287 0.164700058 iYLR199C 0.613079711 0.497366321 0.518884226 YLR199C -- unknown -- unknown function YLR204W QRI5 1 24 1.6 0.4287 0.268177826 iYLR203C 0.403671151 0.280584799 0.382066277 QRI5 -- unknown -- unknown function YLR223C IFH1 1 24 1.6 0.4287 0.238437666 iYLR223C 0.278221469 0.24002304 0.252900419 "IFH1 -- rRNA processing -- regulation of ribosomal RNA expression, may function in conjunction with Fhl1p" YLR274W CDC46 1 23 1.6 0.4287 0.545981705 iYLR273C 0.37736875 0.77544187 0.552456184 "CDC46 -- DNA replication -- Member of MCM/P1 family, component of MCM complex that binds at ARS elements to initiate DNA replication" YML038C YMD8 1 23 1.6 0.4287 0.781688977 iYML038C 0.397417772 0.943522398 0.162814081 "YMD8 -- unknown -- similarity to vanadate resistance protein Gog5p, member of triose phosphate translocater family of membrane transporters" YOR023C AHC1 1 24 1.6 0.4287 0.606884793 iYOR023C 0.200981889 0.897262589 0.130667325 AHC1 -- chromatin structure -- Component of ADA histone acetyltransferase complex YBR129C OPY1 0.9 20 1.6 0.4287 0.552694386 iYBR129C 0.554788183 0.944540443 0.481919567 OPY1 -- mating -- imparts Far- phenotype YBR208C "DUR1,2" 0.9 19 1.6 0.4287 0.673391049 iYBR208C 0.247330995 0.507980846 0.621032142 "DUR1,2 -- nitrogen, amino acid, nucleotide metabolism -- Urea amidolyase, contains urea carboxylase and allophanate hydrolase activities" YDL086W YDL086W 0.9 21 1.6 0.4287 0.37549728 iYDL087C 0.43022246 0.605630394 0.417226866 YDL086W -- unknown -- Putative carboxymethylenebutenolidase YDL202W MRPL11 0.9 21 1.6 0.4287 0.466930477 iYDL203C 0.529811989 0.492861176 0.670073375 MRPL11 -- protein synthesis -- Mitochondrial ribosomal large subunit (YmL11) YHR082C KSP1 0.9 21 1.6 0.4287 0.293069293 iYHR082C 0.145986769 0.721308859 0.034677982 KSP1 -- unknown -- Serine/threonine kinase that suppresses prp20 mutant when oveproduced YLR226W BUR2 0.9 20 1.6 0.4287 0.490600652 iYLR225C 0.445695857 0.695490845 0.358604576 "BUR2 -- unknown -- negative regulation of basal trancription, causes chromosome loss when overproduced" YPL215W CBP3 0.9 19 1.6 0.4287 0.641036866 iYPL216W 0.266965114 0.796563685 0.383385744 CBP3 -- respiration -- assembly of ubiquinol cytochrome-c reductase complex (cytochrome bc1 complex) YBL047C YBL047C 0.8 19 1.6 0.4287 0.564595225 iYBL047C 0.763733693 0.322106943 0.850628424 YBL047C -- unknown -- similarity to cytoskeletal proteins Uso1p and Pan1p and to mouse tyrosine kinase substrate eps15 YDR061W YDR061W 0.8 19 1.6 0.4287 0.8119672 iYDR060W 0.378797779 0.533416271 0.163991213 YDR061W -- unknown -- similarity to E. coli photorepair protein YGL043W DST1 0.8 19 1.6 0.4287 0.330282586 iYGL044C 0.031433759 0.330617954 0.060183693 DST1 -- transcription -- Transcription elongation factor S-IIDNA strand transfer protein catalyzing homologous DNA strand exchange YGL107C YGL107C 0.8 19 1.6 0.4287 0.789141663 iYGL107C 0.162585011 0.946761313 0.125191579 YGL107C -- unknown -- unknown function YGL150C INO80 0.8 17 1.6 0.4287 0.145880649 0.407163743 INO80 -- unknown -- Member of Snf2p-like family of probable DNA helicases YGR230W BNS1 0.8 17 1.6 0.4287 0.608137795 iYGR229C 0.484844066 0.674780527 0.841374269 "BNS1 -- unknown -- similarity to Spo12p, able to partially suppress requirement for Spo12p in meiosis" YHR017W YSC83 0.8 18 1.6 0.4287 0.864615091 iYHR016C 0.384188174 0.921044151 0.241526904 YSC83 -- unknown -- unknown function YKL041W VPS24 0.8 18 1.6 0.4287 0.111911893 iYKL042W 0.305374061 0.099042298 0.498396609 VPS24 -- vacuolar protein targeting -- sorting of proteins in pre-vacuolar endosome YKL206C YKL206C 0.8 17 1.6 0.4287 0.572385389 iYKL206C 0.349756546 0.885542664 0.251512463 YKL206C -- unknown -- unknown function YLR357W RSC2 0.8 19 1.6 0.4287 0.318755767 iYLR356W 0.195319471 0.519603477 0.416728811 RSC2 -- chromatin structure -- Component of abundant RSC complex involved in chromatin remodeling YLR412W YLR412W 0.8 19 1.6 0.4287 0.560320465 iYLR411W 0.265655402 0.468197153 0.332259104 YLR412W -- unknown -- unknown function YMR024W MRPL3 0.8 19 1.6 0.4287 0.316631143 iYMR023C itA(AGC)M1 0.690856868 0.140912867 0.589255465 0.658878505 0.412277164 MRPL3 -- protein synthesis -- Mitochondrial ribosomal large subunit (YmL3) YNL197C WHI3 0.8 18 1.6 0.4287 0.11798371 iYNL197C 0.669609704 0.081936835 0.419723988 "WHI3 -- cell size -- regulation of cell size, has 1 RNA recognition (RRM) domain" YOL062C APM4 0.8 18 1.6 0.4287 0.134449161 iYOL062C 0.242611405 0.227014295 0.133203379 "APM4 -- secretion -- Clathrin-associated protein (AP) complex, medium subunit" YOR273C YOR273C 0.8 19 1.6 0.4287 0.307120302 iYOR273C 0.509836178 0.468608574 0.749431449 YOR273C -- unknown -- Member of multidrug-resistance 12-spanner family of major facilitator superfamily (MFS-MDR) YOR297C TIM18 0.8 18 1.6 0.4287 0.530637569 iYOR297C 0.890437441 0.769899285 0.866045688 TIM18 -- mitochondrial protein targeting -- Component of inner mitochondrial membrane translocation complex YOR304W ISW2 0.8 17 1.6 0.4287 0.270617024 iYOR303W 0.789487011 0.053312051 0.437479858 ISW2 -- unknown -- strong similarity to Drosophila nucleosome remodeling factor ISWI (Imitator SWI) YBL025W RRN10 0.7 17 1.6 0.4287 0.212191046 iYBL026W 0.636043124 0.344770838 0.698884758 "RRN10 -- transcription -- Component of Upstream Activation Factor (UAF) complex, involved in activation of RNA polymerase I" YCL005W YCL005W 0.7 15 1.6 0.4287 0.447722829 0.716284045 "YCL005W -- unknown -- unknown function, can mutate to confer daunomycin resistance" YDL054C YDL054C 0.7 16 1.6 0.4287 0.250285918 iYDL054C 0.167644311 0.504821435 0.123801544 YDL054C -- unknown -- unknown function YDR286C YDR286C 0.7 15 1.6 0.4287 0.171055365 iYDR286C 0.0209082 0.541653239 0.115291653 YDR286C -- unknown -- unknown function YDR311W TFB1 0.7 15 1.6 0.4287 0.636193454 iYDR310C 0.34114508 0.674356699 0.377355386 "TFB1 -- transcription -- Component of RNA polymerase II transcription initiation factor TFIIH (factor b), 75 kDa subunit" YGL005C YGL005C 0.7 15 1.6 0.4287 0.671497934 iYGL005C 0.310708776 0.967179323 0.510738089 YGL005C -- unknown -- similarity to Xenopus kinesin-related protein Eg5 PIR YGR065C VHT1 0.7 17 1.6 0.4287 0.408900705 iYGR065C 0.269294809 0.76119884 0.706315523 VHT1 -- transport -- H+/biotin symporter and member of allantoate permease family of major facilitator superfamily (MFS) YGR073C YGR073C 0.7 16 1.6 0.4287 0.431097245 0.454988029 YGR073C -- unknown -- unknown function YGR163W GTR2 0.7 15 1.6 0.4287 0.332257758 iYGR162W 0.460674448 0.371907422 0.685103964 "GTR2 -- signaling (putative) -- Putative small GTPase, has similarity to Gtr1p" YHR119W SET1 0.7 15 1.6 0.4287 0.302579813 iYHR118C 0.266759969 0.565045668 0.241146849 "SET1 -- transcription -- diverse cellular processes including transcription and chromatin structure, member of trithorax family of SET domain-containing proteins" YIR023W DAL81 0.7 15 1.6 0.4287 0.107009875 iYIR022W 0.251633453 0.275161607 "DAL81 -- transcription -- Transcriptional activator for allantoin, 4-aminobutyric acid (GABA), and urea catabolic genescontains a Zn[2]-Cys[6] fungal-type binuclear cluster domain in the N-terminal region" YJL071W ARG2 0.7 16 1.6 0.4287 0.295204149 iYJL072C 0.531523435 0.834198737 0.55425601 "ARG2 -- arginine biosynthesis -- Acetylglutamate synthase, catalyzes the first step in ornithine and arginine biosynthesis" YJL072C YJL072C 0.7 16 1.6 0.4287 0.122195806 iYJL072C 0.531523435 0.360893765 0.55425601 YJL072C -- unknown -- unknown function YJR010C-A SPC1 0.7 15 1.6 0.4287 0.265541298 iYJR010C-A 0.109735509 0.30712214 0.596992227 SPC1 -- secretion -- Subunit of signal peptidase complex YKL143W LTV1 0.7 15 1.6 0.4287 0.521623848 iYKL144C 0.403711658 0.675736994 0.414498141 LTV1 -- unknown -- viability at low temperature YKR062W TFA2 0.7 17 1.6 0.4287 0.69398441 iYKR061W SNR42 0.489991771 0.559334945 0.859813084 0.372339159 0.53616391 "TFA2 -- transcription -- RNA polymerase II transcription initiation factor TFIIE (factor a), 43 kDa subunit" YMR134W YMR134W 0.7 15 1.6 0.4287 0.511323318 iYMR133W 0.171149073 0.496958432 0.196418488 YMR134W -- unknown -- iron metabolism YNL200C YNL200C 0.7 15 1.6 0.4287 0.529308336 iYNL200C 0.594101923 0.703529001 0.63418688 YNL200C -- unknown -- unknown function YNR028W CPR8 0.7 16 1.6 0.4287 0.193352204 iYNR027W 0.433962482 0.372688072 0.363272228 "CPR8 -- protein folding -- Cyclophilin (peptidylprolyl cis-trans isomerase or PPIase), involved in the secretory pathway" YOR228C YOR228C 0.7 16 1.6 0.4287 0.293761345 iYOR228C 0.207274703 0.642857143 0.263391755 YOR228C -- unknown -- unknown function YOR238W YOR238W 0.7 17 1.6 0.4287 0.132177828 iYOR237W 0.263914181 0.232402235 0.309477781 YOR238W -- unknown -- unknown function YPL097W MSY1 0.7 15 1.6 0.4287 0.029197167 iYPL098C 0.208660408 0.042059058 0.03879971 "MSY1 -- protein synthesis -- Tyrosyl-tRNA synthetase, mitochondrial" YBL067C UBP13 0.6 14 1.6 0.4287 0.459270692 iYBL067C 0.487832415 0.400499517 0.50877193 "UBP13 -- protein degradation, ubiquitin-mediated -- Ubiquitin C-terminal hydrolase" YBR251W MRPS5 0.6 13 1.6 0.4287 0.331525229 iYBR250W 0.433924106 0.537823201 0.892125401 "MRPS5 -- protein synthesis -- Mitochondrial ribosomal small subunit,homolog of E. coli ribosomal protein S5" YDR235W PRP42 0.6 13 1.6 0.4287 0.602557619 iYDR234W 0.138976849 0.678778601 0.239439 PRP42 -- mRNA splicing -- U1 snRNA-associated pre-mRNA splicing and U1 snRNP biogenesis YER149C PEA2 0.6 12 1.6 0.4287 0.726727227 iYER149C 0.288297179 0.903463616 0.332742507 PEA2 -- mating -- oriented growth toward mating partner YJL092W HPR5 0.6 14 1.6 0.4287 0.486317457 iYJL093C 0.245531904 0.634990253 0.216987981 HPR5 -- meiosis -- DNA helicase involved in DNA repairsuppressor of rad6 and rad18 YJR019C TES1 0.6 13 1.6 0.4287 0.497698509 0.729367234 "TES1 -- fatty acid metabolism -- Acyl-CoA thioesterase, peroxisomal protein" YJR022W LSM8 0.6 14 1.6 0.4287 0.172787373 iYJR021C 0.306821307 0.471588188 0.035913807 LSM8 -- mRNA splicing -- U6 snRNA-associated Sm-like group YKL075C YKL075C 0.6 14 1.6 0.4287 0.303141457 iYKL075C 0.46489644 0.585287583 0.505606195 YKL075C -- unknown -- unknown function YKL155C YKL155C 0.6 12 1.6 0.4287 0.645003841 iYKL155C 0.256943554 0.339586933 0.16588785 YKL155C -- unknown -- unknown function YLR063W YLR063W 0.6 12 1.6 0.4287 0.62651366 iYLR062C 0.720923065 0.503232006 0.331612487 YLR063W -- unknown -- unknown function YLR183C YLR183C 0.6 14 1.6 0.4287 0.903515408 iYLR183C 0.949892415 0.927919032 0.685308355 YLR183C -- unknown -- unknown function YML023C YML023C 0.6 12 1.6 0.4287 0.877240936 iYML023C 0.381137647 0.921643358 0.235460192 YML023C -- unknown -- unknown function YML062C MFT1 0.6 13 1.6 0.4287 0.205265049 iYML062C 0.548088542 0.170646524 0.4103751 "MFT1 -- mitochondrial protein targeting -- Targeting factor for mitochondrial precursor proteins, member of a family of transmembrane transition metal transporters" YML082W YML082W 0.6 12 1.6 0.4287 0.228347094 iYML083C 0.722986022 0.848775379 YML082W -- unknown -- similarity to O-succinylhomoserine (thiol)-lyase YMR067C YMR067C 0.6 14 1.6 0.4287 0.220443489 iYMR067C 0.473282092 0.686003456 0.491298743 YMR067C -- unknown -- unknown function YMR171C YMR171C 0.6 13 1.6 0.4287 0.493378195 iYMR171C 0.386499444 0.786964588 0.551636073 YMR171C -- unknown -- similarity to Ssh4p YMR293C YMR293C 0.6 14 1.6 0.4287 0.561618502 iYMR293C 0.629314857 0.956498952 0.271189172 YMR293C -- unknown -- similarity to amidases YNL202W SPS19 0.6 13 1.6 0.4287 0.33591582 0.51519709 "SPS19 -- sporulation -- Peroxisomal 2,4-dienoyl-CoA reductase" YOR088W YOR088W 0.6 13 1.6 0.4287 0.32122319 0.715961692 YOR088W -- unknown -- unknown function YOR166C YOR166C 0.6 12 1.6 0.4287 0.474460388 iYOR166C 0.643345406 0.628486793 0.696962313 YOR166C -- unknown -- unknown function YBR055C PRP6 0.4 11 1.6 0.4287 0.625404232 iYBR055C itL(UAA)B2 0.667293685 0.81328513 0.765669113 0.450108897 0.648842777 "PRP6 -- mRNA splicing -- U4/U6.U5 tri-snRNP-associated splicing factor, contains tetratricopeptide (TPR) repeats" YDL036C YDL036C 0.4 11 1.6 0.4287 0.262261388 iYDL036C 0.50307347 0.191911251 0.207711543 YDL036C -- unknown -- similarity to Rib2p YDR336W YDR336W 0.4 12 1.6 0.4287 0.756474644 iYDR335W 0.394446006 0.908077053 0.369209249 YDR336W -- unknown -- unknown function YDR406W PDR15 0.4 11 1.6 0.4287 0.719316107 iYDR405W 0.626868111 0.601272962 0.485062893 PDR15 -- drug resistance -- Member of ATP-binding cassette (ABC) superfamily YFL059W SNZ3 0.4 10 1.6 0.4287 0.198017124 iYFL060C 0.270267725 0.678721174 0.062918448 "SNZ3 -- unknown -- Putative pyridoxine (vitamin B6) biosynthetic enzyme, member of stationary phase-induced gene family which includes Snz1p and Snz3p" YGR004W YGR004W 0.4 11 1.6 0.4287 0.760429639 iYGR003W 0.790430844 0.944422038 0.889703513 YGR004W -- unknown -- unknown function YHR031C RRM3 0.4 11 1.6 0.4287 0.491042548 iYHR031C 0.509132268 0.494846261 0.261220066 RRM3 -- transposition -- DNA helicase that promotes replication fork progression through the ribosomal DNA YHR034C YHR034C 0.4 11 1.6 0.4287 0.680263032 iYHR034C 0.452608731 0.447152341 0.396547552 YHR034C -- unknown -- unknown function YHR036W YHR036W 0.4 12 1.6 0.4287 0.542607754 iYHR035W 0.156861834 0.334353851 0.245139953 YHR036W -- unknown -- unknown function YLR319C BUD6 0.4 11 1.6 0.4287 0.650320695 iYLR319C 0.329794185 0.383913484 0.229974994 "BUD6 -- bud site selection, bipolar -- bipolar buddingmutant strains bud randomly" YLR321C SFH1 0.4 11 1.6 0.4287 0.309866057 0.767787524 SFH1 -- chromatin structure -- Component of abundant chromatin remodeling complex (RSC) YNL035C YNL035C 0.4 12 1.6 0.4287 0.502741948 iYNL035C itI(AAU)N1 0.34094979 0.026225481 0.691287447 0.132477188 0.033242821 YNL035C -- unknown -- unknown function YNL310C YNL310C 0.4 11 1.6 0.4287 0.924703343 0.470679012 YNL310C -- unknown -- unknown function YOR111W YOR111W 0.4 11 1.6 0.4287 0.355620945 iYOR110W 0.318443805 0.454237834 0.191027374 YOR111W -- unknown -- unknown function YOR252W YOR252W 0.4 11 1.6 0.4287 0.041907966 iYOR251C 0.315101262 0.081713318 0.206896552 YOR252W -- unknown -- unknown function YPL096W PNG1 0.4 11 1.6 0.4287 0.043684413 iYPL097W 0.259724963 0.036658073 0.567678762 PNG1 -- unknown -- de-N-glycosylation function YPL108W YPL108W 0.4 10 1.6 0.4287 0.024510069 iYPL109C 0.336404288 0.038255361 0.594253791 YPL108W -- unknown -- unknown function YPL182C YPL182C 0.4 11 1.6 0.4287 0.038985966 0.058263452 YPL182C -- unknown -- unknown function YKL039W PTM1 1.3 33 1.5 0.4096 1 0.881486736 iYKL040C 0.956349534 0.808113223 0.622085355 "PTM1 -- unknown -- Protein possibly involved in the TCA cycle, has strong similarity to Yhl017p" YLR438W CAR2 0.9 23 1.5 0.4096 1 0.965592089 iYLR437C 0.969247087 0.490249321 0.169567421 "CAR2 -- arginine metabolism -- Ornithine aminotransferase (ornithine oxo-acid aminotransferase), acts in the degradation of arginine, citrulline and ornithine" YDR392W SPT3 0.7 15 1.5 0.4096 1 0.983375911 iYDR391C 0.851362871 0.631822865 0.438067785 "SPT3 -- chromatin structure -- Component of nucleosomal histone acetyltransferase (Spt-Ada-Gcn5-Acetyltransferase or SAGA) complex, member of TBP (TATA-binding protein) class of SPT proteins" YBL082C RHK1 0.6 13 1.5 0.4096 1 0.823183727 iYBL082C 0.939385673 0.686322287 0.454851983 "RHK1 -- protein glycosylation -- Mannosyltransferase involved in N-glycosylation, Hansenula mrakii HM-1 killer toxin resistance protein" YNL329C PEX6 0.6 14 1.5 0.4096 1 iYNL329C 0.963249037 0.22417154 PEX6 -- peroxisome biogenesis -- Peroxisomal biogenesis protein (peroxin) of AAA family of ATPases YPL206C YPL206C 2 50 1.5 0.4096 0.071939047 iYPL206C 0.200671653 0.270216032 0.127271139 YPL206C -- unknown -- similarity to Mycoplasma genitalium glycerophosphoryl diester phosphodiesterase YGR199W PMT6 1.6 38 1.5 0.4096 0.590179061 iYGR198W 0.757953779 0.771348763 0.538879289 "PMT6 -- protein glycosylation -- similarity to O-mannosyltransferases Pmt1p, Pmt2p, Pmt3p, Pmt4p and Pmt5p" YKL142W MRP8 1.5 37 1.5 0.4096 0.899750784 iYKL143W 0.165873379 0.888916317 0.031743474 MRP8 -- protein synthesis -- Putative mitochondrial ribosomal small subunit YDL134C PPH21 1.3 31 1.5 0.4096 0.890376901 iYDL134C YDL133C-A 0.917897283 0.926228038 0.689130256 0.737411288 0.310338049 "PPH21 -- cell cycle -- Protein serine/threonine phosphatase PP2A-1, paralog of Pph22p, member of PPP family of protein phosphatases" YPL240C HSP82 1.3 34 1.5 0.4096 0.490663335 iYPL240C 0.543840163 0.459555269 0.598686565 HSP82 -- protein folding -- Heat-inducible chaperonin homologous to E. coli HtpG and mammalian HSP90 YDL132W CDC53 1.2 30 1.5 0.4096 0.811691624 iYDL133W 0.841916803 0.793654764 0.77699001 "CDC53 -- cell cycle -- (cullin homolog) associated with Cdc34p, Skp1p, and F-box proteins in SCF (Skp1p-cullin-F-box) complexes which target many proteins for ubiquitin-dependent degradation" YER035W YER035W 1.2 30 1.5 0.4096 0.453330398 iYER034W 0.316519185 0.537792765 0.023064645 YER035W -- unknown -- unknown function YLR224W YLR224W 1.2 32 1.5 0.4096 0.526857735 iYLR223C 0.278221469 0.632436435 0.252900419 "YLR224W -- unknown -- unknown function, contains an F-box" YCR076C YCR076C 1.1 28 1.5 0.4096 0.161322733 iYCR076C 0.525320741 0.390438575 0.42635025 YCR076C -- unknown -- unknown function YDR028C REG1 1.1 28 1.5 0.4096 0.535171182 iYDR028C 0.63661389 0.361055094 0.591768884 "REG1 -- glucose repression -- Regulatory subunit for protein phosphatase Glc7p, required for glucose repression" YKL088W YKL088W 1.1 26 1.5 0.4096 0.275635301 iYKL089W 0.210686651 0.266480447 0.436700676 YKL088W -- unknown -- similarity to Sis2p YMR161W HLJ1 1.1 29 1.5 0.4096 0.216485447 iYMR160W 0.336205914 0.344585885 0.429093567 HLJ1 -- unknown -- DnaJ homolog that is lethal when overexpressed YDL010W YDL010W 1 25 1.5 0.4096 0.422558513 0.602642604 YDL010W -- unknown -- similarity to Ybr014p and glutaredoxins YGL119W ABC1 1 25 1.5 0.4096 0.804863537 iYGL120C 0.557116181 0.951417983 0.514587701 "ABC1 -- respiration -- assembly of ubiquinol cytochrome-c reductase complex (cytochrome bc1 complex), conserved in many other organisms" YGL130W CEG1 1 26 1.5 0.4096 0.332316757 iYGL131C 0.376959425 0.535855449 0.162011173 CEG1 -- mRNA capping -- mRNA guanylyltransferase subunit of mRNA capping enzyme YIL106W MOB1 1 23 1.5 0.4096 0.39691993 iYIL107C 0.348170533 0.626336792 0.373843285 MOB1 -- mitosis -- completion of mitosis and maintenance of ploidy YJL068C YJL068C 1 24 1.5 0.4096 0.308569559 iYJL068C 0.842210276 0.69702954 0.437340574 "YJL068C -- unknown -- Esterase, may be involved in conversion of formaldehyde to S-formylglutathione" YLR309C IMH1 1 23 1.5 0.4096 0.267232078 iYLR309C 0.911036926 0.202830189 0.752445842 "IMH1 -- secretion (putative) -- Probable coiled-coil protein, single copy and multicopy suppressor of ypt6, contains a Golgi-localization (GRIP) domain" YER176W ECM32 0.9 22 1.5 0.4096 0.371963568 iYER175C 0.388848002 0.576267057 0.541008701 ECM32 -- cell wall biogenesis -- Helicase involved in modulating translation termination efficiency YLR177W YLR177W 0.9 24 1.5 0.4096 0.647000666 iYLR176C 0.597985655 0.808744051 0.552795031 YLR177W -- unknown -- similarity to Psp1p YOL073C YOL073C 0.9 23 1.5 0.4096 0.211868365 iYOL073C 0.478675445 0.302559039 0.083548179 YOL073C -- unknown -- unknown function YPL224C MMT2 0.9 21 1.5 0.4096 0.451327939 iYPL224C 0.268195218 0.575907183 0.220053239 "MMT2 -- mitochondrial ion transport -- mitochondrial iron accumulation, member of a family of transition metal transporters" YBL101C ECM21 0.8 19 1.5 0.4096 0.490327218 YBLWTy2-1A 0.162039332 0.814903699 0.273879142 ECM21 -- cell wall biogenesis -- Protein possibly involved in cell wall structure or biosynthesis YBR046C ZTA1 0.8 18 1.5 0.4096 0.805945538 iYBR046C 0.947858619 0.601915403 0.900718276 "ZTA1 -- unknown -- Zeta-crystallin homolog, has similarity to E. coli quinone oxidoreductase and human zeta-crystallin which has quinone oxidoreductase activity" YBR123C TFC1 0.8 19 1.5 0.4096 0.262801507 0.594863732 "TFC1 -- transcription -- RNA polymerase III transcription initiation factor TFIIIC (tau), 95 kDa subunit" YBR278W DPB3 0.8 19 1.5 0.4096 0.223301571 0.377183788 DPB3 -- DNA replication -- DNA polymerase epsilon third subunit YDL005C MED2 0.8 18 1.5 0.4096 0.106634119 iYDL005C 0.14698607 0.075249758 0.44172812 MED2 -- transcription -- Component of RNA polymerase II holoenzyme and mediator subcomplex YDR407C TRS120 0.8 19 1.5 0.4096 0.532126585 iYDR407C 0.705277579 0.727812718 0.623078267 TRS120 -- secretion (putative) -- TRAPP (TRAnsport Protein Particle) complex involved in vesicular transport from endoplasmic reticulum to Golgi YGR266W YGR266W 0.8 19 1.5 0.4096 0.339492605 iYGR265W 0.369526951 0.745606624 0.511093641 YGR266W -- unknown -- unknown function YHL048W COS8 0.8 20 1.5 0.4096 0.934825776 iYHL049C-0 iYHL049C-1 0.995609492 0.995478522 0.80964853 0.017238627 0.269654088 COS8 -- unknown -- Member of COS family of subtelomerically-encoded proteins YIL147C SLN1 0.8 19 1.5 0.4096 0.641601612 iYIL147C 0.375361128 0.886028608 0.410583206 SLN1 -- signaling -- Two-component signal transducer involved in the high-osmolarity MAP kinase signal transduction pathway that initiates a phosphorelay from Sln1p to Ypd1p to Ssk1p YJR082C YJR082C 0.8 20 1.5 0.4096 0.290717063 iYJR082C 0.266115241 0.482616762 0.414136427 YJR082C -- unknown -- unknown function YLR085C ARP6 0.8 18 1.5 0.4096 0.222535715 iYLR085C 0.469862555 0.807524976 0.329465975 "ARP6 -- cytoskeleton (putative) -- weak similarity to actin and actin-related proteins Arp2p, Arp3p, and Arp5p" YLR201C YLR201C 0.8 20 1.5 0.4096 0.436292338 0.835394644 YLR201C -- unknown -- unknown function YML103C NUP188 0.8 20 1.5 0.4096 0.611046102 iYML103C 0.689224225 0.780430749 0.627096436 NUP188 -- nuclear protein targeting -- Nuclear pore protein (nucleoporin) YMR077C YMR077C 0.8 20 1.5 0.4096 0.2291945 iYMR077C 0.239006832 0.528671215 0.225329503 YMR077C -- unknown -- similarity to Snf7p YNR031C SSK2 0.8 20 1.5 0.4096 0.421867141 iYNR031C 0.054371178 0.453700575 0.143180861 "SSK2 -- signaling, high osmolarity pathway -- Map kinase kinase kinase (MAPKKK) of high-osmolarity signal transduction pathway" YNR057C BIO4 0.8 19 1.5 0.4096 0.631131617 iYNR057C 0.358679439 0.48572369 0.124099526 "BIO4 -- biotin biosynthesis -- Dethiobiotin synthase, component of biotin biosynthesis pathway" YOR231W MKK1 0.8 21 1.5 0.4096 0.113371016 iYOR230W 0.309112786 0.260558804 0.08853781 "MKK1 -- signaling, PKC1 pathway -- Serine/threonine protein kinase of MAP kinase kinase (MEK) family involved in cell wall integrity (low-osmolarity) pathway" YPL085W SEC16 0.8 19 1.5 0.4096 0.287160698 iYPL086C 0.392190594 0.204962939 0.442284424 SEC16 -- secretion -- Hydrophilic vesicle formation in ER to Golgi transport YBL104C YBL104C 0.7 16 1.5 0.4096 0.485590994 iYBL104C 0.531615234 0.583770267 0.704023698 YBL104C -- unknown -- bud shape and cell surface morphology YDR089W YDR089W 0.7 17 1.5 0.4096 0.562222936 iYDR088C itR(ACG)D-0 0.377876881 0.148412869 0.730499314 0.28339984 0.312520142 "YDR089W -- unknown -- unknown function, contains a putative leucine zipper domain" YDR236C FMN1 0.7 18 1.5 0.4096 0.279326351 iYDR236C 0.133376406 0.490009668 0.478202095 FMN1 -- riboflavin metabolism -- Riboflavin kinase YFL007W BLM3 0.7 16 1.5 0.4096 0.542366458 iYFL008W 0.382119313 0.632411067 0.350279525 BLM3 -- drug resustance -- resistence to bleomycin-induced DNA damage YGR216C GPI1 0.7 16 1.5 0.4096 0.617775619 iYGR216C 0.662659153 0.88759977 0.299122107 GPI1 -- protein processing -- involved with Gpi2p and Gpi3p in the first step in glycosylphosphatidylinositol (GPI) anchor synthesis YHL002W YHL002W 0.7 17 1.5 0.4096 0.977444926 iYHL003C 0.395280012 0.802387914 0.335804061 "YHL002W -- unknown -- unknown function, has one SH3 domain" YHL031C GOS1 0.7 16 1.5 0.4096 0.66352669 iYHL031C 0.427004482 0.757772896 0.247675471 GOS1 -- secretion -- SNARE C-terminal membrane anchor YHR050W SMF2 0.7 18 1.5 0.4096 0.388921282 iYHR049C-A 0.602660057 0.768680299 0.640462889 SMF2 -- transport -- Probable manganese transporter YHR111W YHR111W 0.7 17 1.5 0.4096 0.393121709 iYHR110W 0.238974191 0.717679944 0.162533374 "YHR111W -- unknown -- Ubiquitin-activating enzyme that activates ubiquitin related protein, Urm1p" YIL080W 0.7 16 1.5 0.4096 0.118586576 YILWTy3-1D 0.045396015 0.076057462 0.027715114 YJL112W YJL112W 0.7 17 1.5 0.4096 0.415895779 iYJL113W iYJLCdelta3 0.209755023 0.605640844 0.638690035 0.202940182 0.42251462 "YJL112W -- unknown -- unknown function, has WD (WD-40) repeats" YLR202C YLR202C 0.7 16 1.5 0.4096 0.652407966 0.625126732 YLR202C -- unknown -- unknown function YLR371W ROM2 0.7 18 1.5 0.4096 0.402312409 iYLR370C 0.20265614 0.651125272 0.239265762 ROM2 -- signaling -- GDP-GTP exchange factor for Rho1p that is activated by cell wall defects YNL191W YNL191W 0.7 18 1.5 0.4096 0.86218807 iYNL192W 0.520192909 0.806235901 0.443920335 YNL191W -- unknown -- unknown function YNL267W PIK1 0.7 16 1.5 0.4096 0.334993802 iYNL268W 0.473683485 0.423892877 0.625926523 "PIK1 -- cytokinesis -- Phosphatidylinositol 4-kinase (PI 4-kinase), generates PtdIns 4-P" YOL108C INO4 0.7 16 1.5 0.4096 0.236188319 iYOL108C 0.483012777 0.071301966 0.294577471 INO4 -- phospholipid biosynthesis -- Basic helix-loop-helix (bHLH) transcription factor involved in activation of phospholipid synthetic genes YOL119C YOL119C 0.7 16 1.5 0.4096 0.964713102 iYOL119C 0.822942082 0.514285714 0.448113208 "YOL119C -- unknown -- weak similarity to mammalian monocarboxylate transporter proteins, member of monocarboxylate porter (MCP) family of major facilitator superfamily (MFS)" YOR266W PNT1 0.7 17 1.5 0.4096 0.186511718 iYOR265W 0.263740084 0.246112071 0.320319432 "PNT1 -- pentamidine resistance -- translocation of hydrophilic domains of Cox2p across the inner mitochondrial membrane, responsible for pentamidine resistance" YOR336W KRE5 0.7 17 1.5 0.4096 0.598282069 iYOR335C 0.169836688 0.199887069 0.276624395 "KRE5 -- cell wall biogenesis -- beta-1,6-glucan biosynthesis" YCR087W YCR087W 0.6 15 1.5 0.4096 0.053550584 iYCR087C-A 0.419467411 0.103882391 0.554917202 YCR087W -- unknown -- unknown function YDR058C TGL2 0.6 13 1.5 0.4096 0.410901671 iYDR058C itD(GUC)D 0.79715072 0.657742522 0.575657129 0.587727491 0.401396211 TGL2 -- fatty acid metabolism -- Triglyceride lipase YDR451C YDR451C 0.6 14 1.5 0.4096 0.852408968 iYDR451C 0.329136315 0.841363197 0.476935355 "YDR451C -- unknown -- similarity to Yox1p, contains a homeodomain" YDR503C LPP1 0.6 15 1.5 0.4096 0.722625311 iYDR503C 0.134071651 0.920924875 0.102642604 "LPP1 -- phospholipid metabolism -- Lipid phosphate phosphatase, Mg2+-independent" YER076C YER076C 0.6 14 1.5 0.4096 0.369257045 iYER076C 0.686408225 0.676787624 0.757063049 YER076C -- unknown -- similarity to KHR1 killer toxin YGL085W YGL085W 0.6 15 1.5 0.4096 0.689168838 iYGL086W 0.556435805 0.593377377 0.546326136 YGL085W -- unknown -- similarity to Staphylococcus hyicus thermonuclease YGL216W KIP3 0.6 14 1.5 0.4096 0.290385679 0.373816437 "KIP3 -- mitosis -- Kinesin-related protein, involved in pre-anaphase nuclear migration" YGR171C MSM1 0.6 15 1.5 0.4096 0.707761268 iYGR171C 0.374484967 0.822595244 0.414701269 "MSM1 -- protein synthesis -- Methionyl-tRNA synthetase, mitochondrial, member of class I family of aminoacyl-tRNA synthetases" YHR215W PHO12 0.6 13 1.5 0.4096 0.825868067 YHRCTy1-1D iYHRCdelta16-0 0.07155508 0.406427068 0.77119883 0.08162768 0.3953529 "PHO12 -- phosphate metabolism -- Acid phosphatase, secreted" YKL049C CSE4 0.6 15 1.5 0.4096 0.283503089 iYKL049C 0.263578688 0.473343974 0.316911251 "CSE4 -- chromatin structure, centromeric -- similarity to histone H3, required for chromosome segregation" YKL051W YKL051W 0.6 14 1.5 0.4096 0.50862358 iYKL052C 0.20357522 0.792288457 0.243042672 YKL051W -- unknown -- unknown function YKL052C YKL052C 0.6 14 1.5 0.4096 0.277094811 iYKL052C 0.20357522 0.66177301 0.243042672 YKL052C -- unknown -- unknown function YKR055W RHO4 0.6 15 1.5 0.4096 0.635485088 iYKR054C 0.569246994 0.910006498 0.789864326 "RHO4 -- signaling -- GTP-binding protein, member of rho family in the ras superfamily" YLL019C KNS1 0.6 14 1.5 0.4096 0.43876902 iYLL019C YLL018C-A 0.235821568 0.34645678 0.572625698 0.157407407 0.399760575 KNS1 -- unknown -- Serine/threonine protein kinase with unknown role YLR072W YLR072W 0.6 13 1.5 0.4096 0.345334064 iYLR071C 0.294838288 0.276616121 0.128740824 YLR072W -- unknown -- unknown function YLR265C YLR265C 0.6 14 1.5 0.4096 0.947300746 iYLR265C 0.633630877 0.822941034 0.306426397 YLR265C -- unknown -- unknown function YML098W TAF19 0.6 15 1.5 0.4096 0.056290213 iYML099C 0.420249195 0.163111694 0.497950809 "TAF19 -- transcription -- Component of TAF(II) complex (TBP-associated protein complex), required for activated transcription by RNA polymerase II" YMR028W TAP42 0.6 13 1.5 0.4096 0.620032394 iYMR027W 0.302897473 0.403738644 0.322043535 "TAP42 -- signaling -- associated with phosphatases Sit4p and PP2A, possible component of TOR signal transduction pathway" YMR032W HOF1 0.6 15 1.5 0.4096 0.238739133 iYMR031W-A 0.246940479 0.521681889 0.422440014 "HOF1 -- cytokinesis -- cytokinesis, has an SH3 domain" YMR228W MTF1 0.6 14 1.5 0.4096 0.235190124 iYMR227C 0.373876588 0.621578236 0.42974334 MTF1 -- transcription -- Mitochondrial RNA polymerase specificity factordistantly related to bacterial sigma factors YNL053W MSG5 0.6 15 1.5 0.4096 0.144370923 iYNL054W 0.182449182 0.524009024 0.364601333 "MSG5 -- signaling, pheromone pathway -- Dual-specificity protein tyrosine phosphatase (PTPase) involved in adaptation response to pheromone" YNL193W YNL193W 0.6 14 1.5 0.4096 0.450386711 iYNL194C 0.65893599 0.784168518 0.805188527 YNL193W -- unknown -- unknown function YNL233W BNI4 0.6 13 1.5 0.4096 0.385086005 iYNL234W 0.428239795 0.638138259 0.483008311 BNI4 -- cytokinesis -- may be involved in linking chitin synthase III to septins of neck filaments YNL298W CLA4 0.6 13 1.5 0.4096 0.202919831 iYNL299W 0.157598694 0.260264955 0.063048683 CLA4 -- cytokinesis -- Serine/threonine protein kinase required for cytokinesis YOR066W YOR066W 0.6 13 1.5 0.4096 0.173748023 iYOR065W 0.455501959 0.173343974 0.567234008 YOR066W -- unknown -- unknown function YOR301W RAX1 0.6 13 1.5 0.4096 0.919071931 iYOR300W 0.49569791 0.34811566 0.075536904 RAX1 -- cell polarity (putative) -- determination of budding pattern YPL065W VPS28 0.6 15 1.5 0.4096 0.069378567 iYPL066W 0.146124806 0.257976152 0.030198305 VPS28 -- vacuolar protein targeting -- traffic to the vacuole through the endocytic and biosynthetic pathways YIR005W IST3 0.4 11 1.5 0.4096 0.780366882 iYIR004W 0.579382953 0.591457023 0.514479394 "IST3 -- salt tolerance (putative) -- role in sodium tolerance, has one RNA recognition (RRM) domain" YJL071W ARG2 0.4 11 1.5 0.4096 0.295204149 iYJL072C 0.531523435 0.834198737 0.55425601 "ARG2 -- arginine biosynthesis -- Acetylglutamate synthase, catalyzes the first step in ornithine and arginine biosynthesis" YKL218C SRY1 0.4 12 1.5 0.4096 0.37506486 iYKL218C-0 iYKL218C-1 0.30195945 0.142013031 0.816245866 0.259433962 0.428671088 "SRY1 -- serine metabolism -- Pyridoxal 5'phosphate-dependent enzyme, has strong similarity to mouse glial serine racemase and E. coli threonine dehydratase" YNL068C FKH2 0.4 13 1.5 0.4096 0.937776349 iYNL068C 0.972523751 0.409257781 0.284591195 "FKH2 -- unknown -- Homolog of Drosophila forkhead protein, involved in transcriptional silencing, cell morphology and cell cycle" YOL144W YOL144W 0.4 11 1.5 0.4096 0.219355243 iYOL145C 0.484705145 0.302713488 0.227113906 YOL144W -- ribosome biogenesis (putative) -- Nucleolar 60S ribosome biogenesis YER137C YER137C 0.3 9 1.5 0.4096 0.61306267 iSCR1 YERWdelta17 0.339305925 0.529197166 0.430991369 0.397273534 0.593599533 "YER137C -- unknown -- unknown function, has motifs typical of heme-binding site of cytochrome c proteins" YHR122W YHR122W 0.8 20 1.4 0.3851 1 0.953746219 iYHR121W 0.950960688 0.699281724 0.095922677 YHR122W -- unknown -- unknown function YMR100W MUB1 0.8 22 1.4 0.3851 1 0.845603937 iYMR099C 0.941633151 0.745659508 0.461303284 "MUB1 -- bud site selection -- Zinc finger protein, involved in the regulation of bud site selection" YOR367W SCP1 0.7 18 1.4 0.3851 1 0.932389451 iYOR366W 0.947148708 0.57462091 0.643291653 SCP1 -- cytoskeleton (putative) -- similarity to chicken calponin YAL051W OAF1 0.6 15 1.4 0.3851 1 0.609692613 iYAL053W 0.975823088 0.442294694 0.236537861 "OAF1 -- peroxisome proliferation -- Transcription factor required for induction of POX1 on oleate-containing medium, plays a role in peroxisome proliferation" YJR134C SGM1 0.6 14 1.4 0.3851 1 0.795261499 iYJR134C 0.957228679 0.401788592 0.452130275 "SGM1 -- unknown; growth on galactose or mannose -- Putative coiled-coil protein, has similarity to Nuf1p, a component of nucleoskeleton" YFL021W GAT1 0.4 13 1.4 0.3851 1 0.794979796 iYFL022C 0.990286547 0.24820431 0.286136432 "GAT1 -- nitrogen catabolism -- GATA zinc finger transcription factor that plays a supplemental role to Gln3p, activating genes needed to use non-preferred nitrogen sources" YNL254C YNL254C 0.4 12 1.4 0.3851 1 iYNL254C 0.959562311 0.669432807 YNL254C -- unknown -- unknown function YIR038C GTT1 1.7 43 1.4 0.3851 0.755618051 iYIR038C-0 iYIR038C-1 0.17163249 0.468269386 0.83322591 0.426413255 0.450122292 GTT1 -- glutathione metabolism -- Glutathione transferase YDR001C NTH1 1.5 40 1.4 0.3851 0.589816234 iYDR001C 0.158206343 0.892590564 0.208704147 NTH1 -- trehalose metabolism -- Neutral trehalase YCR003W MRPL32 1.3 36 1.4 0.3851 0.863606664 iYCR002C 0.598642436 0.837526205 0.68499601 MRPL32 -- protein synthesis -- Mitochondrial ribosomal large subunit YCR023C YCR023C 1.1 30 1.4 0.3851 0.449597731 iYCR023C 0.576853969 0.700996958 0.688504542 YCR023C -- unknown -- Member of multidrug-resistance 12-spanner family of major facilitator superfamily (MFS-MDR) YMR090W YMR090W 1.1 28 1.4 0.3851 0.2296638 iYMR089C 0.352043753 0.527128005 0.599760575 YMR090W -- unknown -- similarity to malate dehydrogenases YBR026C YBR026C 1 25 1.4 0.3851 0.514559827 0.784762833 "YBR026C -- mitochondrial respiration -- Nuclear protein essential for mitochondrial respiratory function, binds preferentially to single-stranded core sequence of ARS DNA" YGR035C YGR035C 1 27 1.4 0.3851 0.473272389 iYGR035C 0.733932972 0.470336542 0.439083821 YGR035C -- unknown -- unknown function YNL294C YNL294C 1 28 1.4 0.3851 0.1709412 iYNL294C 0.319203437 0.530854239 0.543841252 YNL294C -- unknown -- unknown function YOR042W YOR042W 1 26 1.4 0.3851 0.280878923 0.185796646 YOR042W -- unknown -- unknown function YBL101W-B 0.9 24 1.4 0.3851 0.596729804 YBLWTy2-1B YBLWTy2-1A 0.079731261 0.162039332 0.813886411 0.041420591 0.273879142 YBR113W YBR113W 0.9 23 1.4 0.3851 0.188676173 0.315642458 YBR113W -- unknown -- unknown function YGL151W NUT1 0.9 22 1.4 0.3851 0.373077546 iYGL152C 0.515541525 0.1075364 NUT1 -- mating type switching -- Component of RNA polymerase II mediator (SRB) subcomplex YGL224C YGL224C 0.9 25 1.4 0.3851 iYGL224C 0.172873024 0.132066157 YGL224C -- unknown -- unknown function YIL105C YIL105C 0.9 23 1.4 0.3851 0.51005929 iYIL105C 0.056852876 0.325652594 0.275941142 YIL105C -- unknown -- similarity to Ask10p and Ynl047p YLR398C SKI2 0.9 24 1.4 0.3851 0.607616742 iYLR398C 0.893182656 0.375897845 0.865584836 "SKI2 -- mRNA decay and virus resistance -- Antiviral protein and probable helicase, part of a system to protect cells from double-stranded RNA (dsRNA) viruses" YLR443W ECM7 0.9 25 1.4 0.3851 0.271247068 iYLR442C 0.255065072 0.367996808 0.276478233 ECM7 -- cell wall biogenesis -- Protein possibly involved in cell wall structure or biosynthesis YOL090W MSH2 0.9 22 1.4 0.3851 0.179941719 iYOL091W 0.400503369 0.422440913 0.223799035 "MSH2 -- DNA repair -- Component with Msh3p and Msh6p of DNA mismatch binding factor, involved in repair of single base mismatches and short insertions/deletions" YPL001W HAT1 0.9 22 1.4 0.3851 0.307747295 iYPL002C 0.489405214 0.708316528 0.509092405 HAT1 -- chromatin structure -- Histone acetyltransferaseacetylates lys12 of histone H4 YBR059C AKL1 0.8 20 1.4 0.3851 0.426969778 iYBR059C 0.77335276 0.538275389 0.387102014 AKL1 -- unknown -- Serine/threonine protein kinase of unknown function YDL161W ENT1 0.8 21 1.4 0.3851 0.148998255 0.322908237 ENT1 -- endocytosis (putative) -- Epsin homolog required for endocytosis YFR002W NIC96 0.8 20 1.4 0.3851 0.57276592 iYFR001W 0.220576332 0.832136807 0.701263584 "NIC96 -- nuclear protein targeting -- Nuclear pore protein (nucleoporin), acts in a complex with Nsp1p, Nup57p, and Nup49p" YGL233W SEC15 0.8 21 1.4 0.3851 0.704274347 iYGL234W 0.407236523 0.870869912 0.514964982 SEC15 -- secretion -- Component of exocyst complex required for exocytosis YHR073W YHR073W 0.8 19 1.4 0.3851 0.710225417 iYHR072W 0.371365567 0.863434702 0.431674733 YHR073W -- unknown -- similarity to human oxysterol-binding protein (OSBP) YHR077C NMD2 0.8 21 1.4 0.3851 0.202947984 iYHR077C 0.450036201 0.170328314 0.413712536 "NMD2 -- mRNA decay, nonsense-mediated -- involved with Nam7p and Upf3p in decay of mRNA containing nonsense codons" YIL135C YIL135C 0.8 21 1.4 0.3851 0.276225624 iYIL135C SNR68 0.745264692 0.571946174 0.282669462 0.448172945 YIL135C -- unknown -- unknown function YJR056C YJR056C 0.8 21 1.4 0.3851 0.450855904 iYJR056C itY(GUA)J2 0.084391002 0.628386515 0.681517886 0.034723936 0.417197709 YJR056C -- unknown -- unknown function YLR181C YLR181C 0.8 21 1.4 0.3851 0.199744969 iYLR181C 0.109816559 0.334307992 0.083000798 YLR181C -- unknown -- unknown function YLR326W YLR326W 0.8 21 1.4 0.3851 0.949594372 iYLR325C 0.087127668 0.565863033 0.066387029 YLR326W -- unknown -- unknown function YOR014W RTS1 0.8 21 1.4 0.3851 0.452338219 iYOR013W 0.105454245 0.389862585 0.027183996 "RTS1 -- stress response -- Protein serine/threonine phosphatase 2A (PP2A), B' regulatory subunit, involved in regulation of stress-related responses and the cell cycle" YOR104W YOR104W 0.8 20 1.4 0.3851 0.233478076 iYOR103C 0.756728032 0.129305477 0.585688368 YOR104W -- unknown -- unknown function YAL026C DRS2 0.7 19 1.4 0.3851 0.734037473 iYAL026C 0.171415175 0.635073002 0.546367152 "DRS2 -- transport -- Membrane-spanning Ca-ATPase (P-type) required for ribosome assembly and involved in late Golgi function, member of cation transporting (E1-E2) P-type ATPase superfamily" YBR063C YBR063C 0.7 19 1.4 0.3851 0.871113548 0.976796648 YBR063C -- unknown -- similarity to phosphopanthethein-binding proteins YBR095C YBR095C 0.7 18 1.4 0.3851 0.84808886 iYBR095C 0.557440309 0.956118416 0.421446987 "YBR095C -- unknown -- unknown function, required for wild-type cell cycle, budding, mating, and pseudohyphal growth" YBR235W YBR235W 0.7 19 1.4 0.3851 0.256688037 iYBR234C 0.146099442 0.207197451 0.151407599 YBR235W -- unknown -- similarity to mammalian cation-chloride cotransporters including the human gene SLC12A1 associated with Bartter's and Long Q-T syndromes YDL225W YDL225W 0.7 18 1.4 0.3851 0.241865073 iYDL226C 0.622969964 0.27918502 0.633259278 "YDL225W -- cytokinesis -- Septin, component of 10 nm filaments of mother-bud neckinvolved in cytokinesis" YDR370C YDR370C 0.7 19 1.4 0.3851 0.530638941 iYDR370C 0.561744994 0.967757382 0.606509829 YDR370C -- unknown -- unknown function YEL020C YEL020C 0.7 16 1.4 0.3851 0.460027337 iYEL021W iYEL020C 0.774405051 0.610228664 0.81888495 0.690615719 0.653583477 "YEL020C -- unknown -- similarity to oxalyl-CoA decarboxylase from Oxalobacter formigenes, contains motifs typical of thiamine pyrophosphate enzymes" YER058W PET117 0.7 17 1.4 0.3851 0.597054836 iYER057C 0.693018127 0.348955392 0.189091202 PET117 -- respiration -- assembly of cytochrome oxidase YGL153W PEX14 0.7 16 1.4 0.3851 0.160132162 iYGL154C 0.536338537 0.397432733 0.374912648 PEX14 -- peroxisomal protein targeting -- Peroxisomal peripheral membrane protein YHR167W YHR167W 0.7 17 1.4 0.3851 0.378928997 iYHR166C 0.255674108 0.812130886 0.515227199 YHR167W -- unknown -- unknown function YIR021W MRS1 0.7 19 1.4 0.3851 0.720911449 iYIR020W-B-0 iYIR020W-B-1 0.497840958 0.375356361 0.811002662 0.526372089 0.601334639 "MRS1 -- mRNA splicing, COB mRNA -- mitochondrial RNA splicing of COB mRNA" YJR136C YJR136C 0.7 17 1.4 0.3851 0.66787971 iYJR136C iYJR135C 0.75462109 0.723948767 0.814050918 0.422736062 0.490822027 YJR136C -- unknown -- unknown function YKR049C YKR049C 0.7 19 1.4 0.3851 0.166957637 iYKR049C 0.176103804 0.508833255 0.303849903 YKR049C -- unknown -- unknown function YLR039C RIC1 0.7 16 1.4 0.3851 0.418443233 iYLR039C 0.293048861 0.641234289 0.132512229 RIC1 -- transcription -- transcription of ribosomal genes and ribosomal RNA genes YLR084C RAX2 0.7 19 1.4 0.3851 0.59686377 iYLR084C 0.226110339 0.957634521 0.20684202 RAX2 -- cell polarity (putative) -- bipolar budding YLR096W KIN2 0.7 17 1.4 0.3851 0.402462614 iYLR095C 0.396597729 0.681697185 0.365012754 "KIN2 -- unknown -- Serine/threonine protein kinase, related to Kin1p and S. pombe KIN1" YLR138W NHA1 0.7 18 1.4 0.3851 0.183551356 iYLR137W 0.285396659 0.120109704 0.379682563 NHA1 -- transport (putative) -- Putative Na+/H+ antiporter YML031W NDC1 0.7 17 1.4 0.3851 0.223599405 0.353529143 "NDC1 -- cytoskeleton -- spindle pole body duplicationcomponent of nuclear envelope, may be involved in nuclear envelope insertion of spindle pole body" YML102W CAC2 0.7 16 1.4 0.3851 0.177244766 iYML103C 0.689224225 0.38858739 0.627096436 "CAC2 -- chromatin structure -- Chromatin assembly complex subunit 1, involved in nucleosome assembly linked with DNA replication, has WD (WD-40) repeats" YMR019W STB4 0.7 17 1.4 0.3851 0.493619884 iYMR018W 0.373380635 0.754628487 0.622076023 STB4 -- transcription -- Sin3p-binding proteinhas Zn[2]-Cys[6] fungal-type binuclear cluster domain in the N-terminal region YMR021C MAC1 0.7 17 1.4 0.3851 0.727490285 iYMR021C 0.481649125 0.929176414 0.601216627 MAC1 -- metal-dependent gene regulation -- Transcription factor involved in induction of genes required for the reduction and utilization of iron and copper YOR299W BUD7 0.7 19 1.4 0.3851 0.257001177 YOR298C-A iYOR298C-A 0.792870994 0.613666475 0.586991221 0.628826942 0.332016786 "BUD7 -- bud site selection, bipolar -- bipolar budding pattern" YOR322C YOR322C 0.7 18 1.4 0.3851 0.133893879 iYOR322C 0.309648002 0.279099782 0.649108282 YOR322C -- unknown -- unknown function YPR156C YPR156C 0.7 17 1.4 0.3851 0.1710131 iYPR156C 0.294502549 0.187525961 0.613277473 YPR156C -- unknown -- Member of multidrug-resistance 12-spanner family of major facilitator superfamily (MFS-MDR) YBL095W YBL095W 0.6 13 1.4 0.3851 0.901955943 0.937378168 YBL095W -- unknown -- unknown function YBR188C NTC20 0.6 14 1.4 0.3851 0.95278879 iYBR188C 0.986112327 0.317611711 0.827827908 NTC20 -- mRNA splicing -- Splicing factor and component of Prp19p-associated complex YBR195C MSI1 0.6 17 1.4 0.3851 0.699854298 iYBR195C 0.843035139 0.802611171 0.805269094 "MSI1 -- chromatin structure -- Chromatin assembly complex, subunit 3, involved in nucleosome assembly linked with DNA replication, has WD (WD-40) repeats" YBR245C ISW1 0.6 14 1.4 0.3851 0.232703463 0.262246213 "ISW1 -- unknown -- Putative ATP-dependent chromatin remodelng factor, has strong similarity to Drosophila nucleosome remodeling factor ISWI" YCL027W FUS1 0.6 13 1.4 0.3851 0.275918505 iYCL028W 0.73123893 0.243796326 0.755039908 "FUS1 -- mating; cell fusion -- cell fusion during mating, has an SH3 domain, localized to the tip of mating projection" YDL241W YDL241W 0.6 16 1.4 0.3851 0.55026712 iYDL242W 0.204408219 0.041058321 0.42708669 "YDL241W -- unknown -- unknown function, induced during anaerobic growth" YDR049W YDR049W 0.6 14 1.4 0.3851 0.320276196 0.278265107 "YDR049W -- unknown -- unknown function, has a single C2H2-type zinc finger" YDR239C YDR239C 0.6 14 1.4 0.3851 0.1180512 iYDR239C 0.567751888 0.360571106 0.664498141 YDR239C -- unknown -- unknown function YDR331W GPI8 0.6 16 1.4 0.3851 0.356528044 iYDR330W 0.461728648 0.805397844 0.351455997 "GPI8 -- protein processing -- Probable component, with Gaa1p, of a glycosylphosphatidylinositol (GPI) transamidase involved in the attachment of GPI anchors to proteins" YDR352W YDR352W 0.6 14 1.4 0.3851 0.412236074 iYDR351W 0.574624375 0.777848239 0.600757015 YDR352W -- unknown -- unknown function YER114C BOI2 0.6 14 1.4 0.3851 0.368772362 iYER114C 0.670090007 0.653551476 0.406544294 "BOI2 -- bud emergence -- bud formation that binds to Bem1p, has an SH3 domain" YGL060W YGL060W 0.6 15 1.4 0.3851 0.453362977 iYGL061C 0.145887885 0.948747908 0.305985634 YGL060W -- unknown -- unknown function YGR012W YGR012W 0.6 14 1.4 0.3851 0.482791874 iYGR011W 0.452328249 0.802474062 0.637573607 YGR012W -- unknown -- similarity to Cys4p YGR030C POP6 0.6 16 1.4 0.3851 0.906332093 iYGR030C 0.712805569 0.976687908 0.716617934 "POP6 -- tRNA processing -- Subunit of both RNase P and RNase MRP, which are invovled in tRNA processing and 5.8S rRNA processing, respectively" YGR121C MEP1 0.6 14 1.4 0.3851 0.269251186 iYGR121C 0.378607501 0.535231497 0.744639376 "MEP1 -- transport -- Ammonia permease of high capacity and moderate affinity, member of ammonium transporter family of membrane transporters" YHL023C YHL023C 0.6 14 1.4 0.3851 0.337021266 iYHL023C itH(GUG)H 0.376223176 0.691052926 0.431276184 0.228891395 0.190627031 YHL023C -- unknown -- unknown function YHR214W YHR214W 0.6 14 1.4 0.3851 0.3262131 iYHR213W-0 iYHR213W-A 0.152023491 0.122788278 0.504317403 0.436932215 0.168553565 YHR214W -- unknown -- unknown function YJL020C YJL020C 0.6 15 1.4 0.3851 0.127530306 iYJL020C 0.471372505 0.146750524 0.470562544 "YJL020C -- unknown -- unknown function, has an SH3 domain" YJL209W CBP1 0.6 14 1.4 0.3851 0.521360788 iYJL210W 0.084614113 0.816192922 0.07338264 "CBP1 -- mRNA stability, COB mRNA -- COB mRNA stability or 5' processing, interacts with 5' end of COB mRNA" YJR137C ECM17 0.6 13 1.4 0.3851 0.680399319 iYJR137C 0.649887848 0.801900585 0.734468855 ECM17 -- cell wall biogenesis -- Putative sulfite reductase YJR149W YJR149W 0.6 14 1.4 0.3851 0.556519713 iYJR148W 0.424928525 0.778102664 0.477844022 YJR149W -- unknown -- similarity to 2-nitropropane dioxygenase YKL189W HYM1 0.6 16 1.4 0.3851 0.457828214 iYKL190W YKLCdelta2 0.495531742 0.562893299 0.600809116 0.365330322 0.531743474 HYM1 -- unknown -- sporulation with similarity to Aspergillus nidulans hymA which is involved in conidiophore development YKL219W COS9 0.6 15 1.4 0.3851 0.676139794 iYKL220C-0 iYKL220C-1 0.678752311 0.418113304 0.893280632 0.561524968 0.720834676 COS9 -- unknown -- Member of COS family of subtelomerically-encoded proteins YLL055W YLL055W 0.6 15 1.4 0.3851 0.432548957 iYLL056C-0 iYLL056C-1 0.272481281 0.467902053 0.695580014 0.468079922 0.671291441 YLL055W -- unknown -- similarity to Dal5p and other members of allantoate permease family of major facilitator superfamily (MFS) YLR094C GIS3 0.6 16 1.4 0.3851 0.503949374 iYLR094C 0.397539214 0.693522398 0.204968944 GIS3 -- unknown -- unknown function YLR115W CFT2 0.6 16 1.4 0.3851 0.344588221 iYLR114C 0.404842951 0.561146052 0.586975362 CFT2 -- mRNA 3'-end processing -- Component of pre-mRNA cleavage factor II YLR155C ASP3A 0.6 14 1.4 0.3851 0.492476933 iYLR155C-0 iYLR155C-A 0.081218203 0.169040735 0.852176738 0.441736548 0.233778303 "ASP3A -- asparagine utilization -- L-asparaginase II, extracellular" YLR166C SEC10 0.6 16 1.4 0.3851 0.847969454 iYLR166C 0.98895835 0.744234801 0.74597164 SEC10 -- secretion -- Component of exocyst complex required for exocytosis YML005W YML005W 0.6 15 1.4 0.3851 0.715486579 iYML006C tS(AGA)M 0.357106052 0.641661297 0.912584596 0.313352827 0.30573631 YML005W -- unknown -- unknown function YML029W YML029W 0.6 14 1.4 0.3851 0.403513032 iYML030W 0.414588422 0.780310971 0.440993789 YML029W -- unknown -- unknown function YML071C YML071C 0.6 14 1.4 0.3851 0.31305129 iYML071C tR(UCU)M2 0.894407765 0.563308948 0.152273202 0.848108413 0.225481142 YML071C -- unknown -- unknown function YML107C YML107C 0.6 15 1.4 0.3851 0.363746147 iYML107C 0.692326372 0.639972344 0.418649673 YML107C -- unknown -- unknown function YMR218C TRS130 0.6 14 1.4 0.3851 0.473671534 iYMR218C 0.404592458 0.798834066 0.36326826 TRS130 -- secretion -- Component of TRAPP (Transport Protein Particle) complex involved in vesicular transport between the ER and the Golgi YNL086W YNL086W 0.6 14 1.4 0.3851 0.476037019 iYNL087W 0.291663317 0.81978709 0.167190776 YNL086W -- unknown -- unknown function YOL011W PLB3 0.6 14 1.4 0.3851 0.493133976 iYOL012C 0.360315012 0.501960691 0.498227558 PLB3 -- phospholipid metabolism -- Phospholipase B (lysophospholipase) YOR201C PET56 0.6 15 1.4 0.3851 0.294389237 iYOR201C 0.309070519 0.48364486 0.095710355 "PET56 -- rRNA processing, mitochondrial -- Ribose methyltransferase specific for G2270 in mitochondrial 21S rRNA" YOR279C YOR279C 0.6 14 1.4 0.3851 0.010699388 iYOR279C 0.685848653 0.077094972 0.449321628 YOR279C -- unknown -- unknown function YPL279C YPL279C 0.6 14 1.4 0.3851 0.287922149 iYPL279C 0.086140878 0.497378398 0.128095507 YPL279C -- unknown -- unknown function YBL098W YBL098W 0.4 11 1.4 0.3851 0.849492644 iYBL099W 0.765674598 0.996289425 0.520192633 YBL098W -- unknown -- Kylnurenine 3-hydroxylase involved in tryptophan degradation and nicotinic acid synthesis YDR088C SLU7 0.4 13 1.4 0.3851 0.07487389 iYDR088C itR(ACG)D-0 0.377876881 0.148412869 0.213905898 0.28339984 0.312520142 "SLU7 -- mRNA splicing -- Pre-mRNA splicing factor affecting 3' splice site choice, required for the second catalytic step of splicing" YDR303C YDR303C 0.4 12 1.4 0.3851 0.749738725 iYDR303C 0.518028361 0.916427912 0.676937969 "YDR303C -- unknown -- similarity to transcription factors, has Zn[2]-Cys[6] fungal-type binuclear cluster domain in the N-terminal region" YFR043C YFR043C 0.4 14 1.4 0.3851 0.280971714 iYFR043C 0.557015369 0.658796603 0.508843079 YFR043C -- unknown -- unknown function YGL027C CWH41 0.4 11 1.4 0.3851 0.344503804 iYGL027C 0.24818907 0.854588986 0.147777688 "CWH41 -- cell wall biogenesis -- Glucosidase I, type II integral N-glycoendoplasmic reticulum involved in beta-1,6-glucan assembly" YGR010W YGR010W 0.4 12 1.4 0.3851 0.300364495 iYGR009C 0.360322167 0.347964884 0.34660814 YGR010W -- unknown -- Possible nicotinamide mononucleotide (NMN) adenylyltransferase YHR129C ARP1 0.4 12 1.4 0.3851 0.52781106 iYHR129C 0.258406869 0.502739285 0.33209907 ARP1 -- cytoskeleton -- Actin-related protein (centractin) of dynactin complex YIL140W SRO4 0.4 13 1.4 0.3851 0.370311361 0.716919393 "SRO4 -- bud site selection, axial -- Membrane glycoprotein localized at site of bud emergence, required for axial budding pattern" YJR051W OSM1 0.4 13 1.4 0.3851 0.377478951 iYJR050W 0.397905334 0.844183049 0.373719448 OSM1 -- anaerobic growth (putative) -- Mitochondrial soluble fumarate reductase involved in osmotic regulation YJR097W YJR097W 0.4 12 1.4 0.3851 0.570103381 iYJR096W 0.526157538 0.677260628 0.785262924 YJR097W -- unknown -- similarity to E. coli DnaJ YKR047W YKR047W 0.4 13 1.4 0.3851 0.326062244 iYKR046C 0.184725501 0.255478569 0.250873515 YKR047W -- unknown -- unknown functionquestionable ORF YLR278C YLR278C 0.4 11 1.4 0.3851 0.567437531 iYLR278C 0.581149283 0.408294248 0.238060429 YLR278C -- unknown -- similarity to transcription factorshas Zn[2]-Cys[6] fungal-type binuclear cluster domain in the N-terminal region YLR419W YLR419W 0.4 11 1.4 0.3851 0.43416503 iYLR418C 0.338867449 0.261272889 0.475273595 "YLR419W -- unknown -- Member of DEAH-box RNA helicase family, possibly involved in pre-mRNA splicing" YMR166C YMR166C 0.4 12 1.4 0.3851 0.162619395 iYMR166C 0.155728169 0.191387142 0.08697441 YMR166C -- unknown -- Member of mitochondrial carrier (MCF) protein family of membrane transporters YOL083W YOL083W 0.4 13 1.4 0.3851 0.696503655 iYOL084W 0.57766472 0.796809539 0.229455366 YOL083W -- unknown -- unknown function YOL128C YOL128C 0.4 11 1.4 0.3851 0.94416949 iYOL128C 0.995341592 0.884015595 0.676952193 YOL128C -- unknown -- Serine/threonine protein kinase with strong similarity to Mck1p YOR074C CDC21 0.4 12.5 1.4 0.3851 0.095575744 iYOR074C 0.159861244 0.247885076 0.270151636 "CDC21 -- DNA replication -- Thymidylate synthase, converts dUMP to dTMP" YOR149C SMP3 0.4 13 1.4 0.3851 0.474515085 iYOR149C 0.246080875 0.78565627 0.75337952 SMP3 -- plasmid maintenance -- plasmid maintenancefunctions in the protein kinase C pathway YOR330C MIP1 0.4 13 1.4 0.3851 0.138056845 iYOR330C 0.511317178 0.204969966 0.223724231 MIP1 -- DNA replication -- Mitochondrial DNA-directed DNA polymerase YPL046C ELC1 0.4 11 1.4 0.3851 0.822468475 iYPL046C 0.156003561 0.478986852 0.177263289 ELC1 -- transcription -- Elongin C transcription elongation regulatory factor for RNA polymerase II YPL267W YPL267W 0.4 13 1.4 0.3851 0.5238407 iYPL268W 0.363342589 0.643627088 0.376222921 YPL267W -- unknown -- unknown function YPR127W YPR127W 0.4 13 1.4 0.3851 0.353357164 iYPR126C 0.508557068 0.500730994 0.359649123 YPR127W -- unknown -- similarity to S. pombe pyridoxal reductase YPR172W YPR172W 0.4 10 1.4 0.3851 0.640358698 iYPR171W 0.082886334 0.661811898 0.123509507 YPR172W -- unknown -- unknown function YDR482C YDR482C 0.3 10 1.4 0.3851 0.036066035 iYDR482C 0.079084345 0.090408805 0.118433774 YDR482C -- unknown -- unknown function YPR194C YPR194C 0.3 9 1.4 0.3851 0.195238665 iYPR194C 0.404339091 0.49068323 0.592643381 YPR194C -- unknown -- Member of oligopeptide transporter (OPT) family of membrane transporters YFL016C MDJ1 1.6 46 1.3 0.3606 1 0.691208593 iYFL016C 0.922973658 0.2406314 0.37600709 "MDJ1 -- protein folding -- mitochondrial biogenesis and folding, member of DnaJ family of chaperones" YKL040C NFU1 0.8 21 1.3 0.3606 1 0.37532883 iYKL040C 0.956349534 0.541017988 0.622085355 NFU1 -- iron homeostasis -- similarity to Anabaena nitrogen fixing protein nifU YDR325W YCG1 0.6 17 1.3 0.3606 1 0.909588182 iYDR324C 0.98405641 0.721961656 0.604979053 "YCG1 -- mitosis, chromosome condensation (putative) -- Subunit of condensin protein complex required for proper chromosome condensation and segregation" YGL142C GPI10 0.4 14 1.3 0.3606 1 0.308638987 iYGL142C 0.977497167 0.523934312 0.122274336 GPI10 -- phospholipid metabolism -- glycosyl phosphatidylinositol (GPI) synthesis YCL017C NFS1 2 57 1.3 0.3606 0.256300443 iYCL017C 0.710426883 0.598854562 0.561691939 "NFS1 -- tRNA splicing -- Essential mitochondrial coordinately regulates iron-sulfur cluster proteins, cellular iron uptake, and iron distribution" YCR083W TRX3 1.6 45 1.3 0.3606 0.349314544 iYCR082W 0.237910884 0.605200362 0.411811652 TRX3 -- oxidative stress response -- Mitochondrial thioredoxinhas similarity to cytoplasmic thioredoxins Trx1p and Trx2p YCR020C-A MAK31 1.2 36 1.3 0.3606 0.578485295 iYCR020C-A YCR020W-B 0.623923035 0.681512178 0.516440543 0.771599612 0.639936701 "MAK31 -- dsRNA virus propagation -- structural stability of L-A double-stranded RNA- (dsRNA-) containing particles, has similarity to snRNA-associated proteins of Sm family" YNL212W VID27 1.2 37 1.3 0.3606 0.278748775 iYNL213C 0.441676831 0.618756043 0.591221069 "VID27 -- unknown -- Membrane-associated regulation of fructose-1,6-bisphosphatase import into Vid vesicles, has similarity to tomato dem [defective embryo and meristems]" YCR069W SCC3 1.1 33 1.3 0.3606 0.916490629 iYCR068W 0.497523059 0.502056949 0.361218606 "SCC3 -- protein folding -- Cyclophilin (peptidylprolyl cis-trans isomerase or PPIase) of endoplasmic reticulum membrane, homolog of Aspergillus nidulans ninA" YHR199C YHR199C 1.1 33 1.3 0.3606 0.448809252 iYHR199C 0.367103494 0.842096602 0.334957765 YHR199C -- unknown -- similarity to Yhr198p YPL058C PDR12 1.1 32 1.3 0.3606 0.626572742 iYPL058C-0 iYPL058C-1 0.156426263 0.282282409 0.338374451 0.088973139 0.245206945 "PDR12 -- drug resistance -- weak organic acid resistance, member of ATP-binding cassette (ABC) superfamily of membrane transporters" YDR411C YDR411C 1 29 1.3 0.3606 0.675870238 iYDR411C 0.42703309 0.919820885 0.27559399 YDR411C -- unknown -- unknown function YKL109W HAP4 1 29 1.3 0.3606 0.499373828 iYKL110C-0 iYKL110C-1 0.291102111 0.279584621 0.544293695 0.805426975 0.236923327 "HAP4 -- transcription -- Transcription factor with acidic activation domain, component of Hap2p-Hap3p-Hap4p-Hap5p complex involved in activation of CCAAT box-containing genes" YPL009C YPL009C 1 28 1.3 0.3606 0.476605223 iYPL009C 0.270149561 0.520549058 0.385964912 YPL009C -- unknown -- unknown function YBR005W YBR005W 0.9 26 1.3 0.3606 0.682612919 iYBR004C 0.634299954 0.98139413 0.696986787 "YBR005W -- unknown -- unknown function, mRNA abundance is reduced by the drug FK506 in a calcineurin- and immunophilin-dependent manner" YER151C UBP3 0.9 27 1.3 0.3606 0.39094429 iYER151C 0.395823215 0.557382283 "UBP3 -- protein degradation, ubiquitin-mediated -- Ubiquitin-specific protease, ubiquitin C-terminal hydrolase" YLR019W PSR2 0.9 27 1.3 0.3606 0.150043007 iYLR018C 0.434846148 0.459394135 0.398004789 "PSR2 -- unknown -- unknown function, required for sodium stress response" YDR148C KGD2 0.8 21 1.3 0.3606 0.361387567 iYDR148C 0.209997198 0.406542056 0.21915403 KGD2 -- TCA cycle -- 2-oxoglutarate dehydrogenase complex E2 component YFR048W YFR048W 0.8 24 1.3 0.3606 0.265916827 iYFR047C 0.544852359 0.707055802 0.333508036 YFR048W -- unknown -- unknown function YMR073C YMR073C 0.8 23 1.3 0.3606 0.402695274 iYMR073C 0.542692446 0.900157233 0.353126007 YMR073C -- unknown -- similarity to rat cytochrome b5 YMR209C YMR209C 0.8 23 1.3 0.3606 0.424040346 iYMR209C 0.433563675 0.805644697 0.701676062 YMR209C -- unknown -- unknown function YPL168W YPL168W 0.8 24 1.3 0.3606 0.569864222 iYPL169C 0.642040715 0.678134064 0.692976856 YPL168W -- unknown -- unknown function YBL096C YBL096C 0.7 20 1.3 0.3606 0.822759313 0.787823201 "YBL096C -- unknown -- unknown function, probably not an expressed ORF" YBR110W ALG1 0.7 21 1.3 0.3606 0.57907806 iYBR109C 0.057840957 0.802469136 0.016121309 ALG1 -- protein glycosylation -- Beta-mannosyltransferase involved in protein N-glycosylation (transfers Man from GDP-Man to Dol-PP-GlcNAc2) YBR200W BEM1 0.7 19 1.3 0.3606 0.708745108 iYBR199W 0.356835789 0.784676776 0.548277809 "BEM1 -- bud emergence -- cell polarization and bud formation, contains two SH3 domains and a PX (phox) domain" YDR003W YDR003W 0.7 20 1.3 0.3606 0.612646865 iYDR002W 0.696213941 0.903563351 0.65871737 YDR003W -- unknown -- similarity to Ybr005p YDR027C LUV1 0.7 20 1.3 0.3606 0.607132025 iYDR027C 0.67102936 0.421985901 0.853638726 "LUV1 -- vacuole biogenesis (putative) -- Subunit of Vps52p-Vps53p-Vps54p complex, involved in protein sorting in the late Golgi" YDR229W YDR229W 0.7 18 1.3 0.3606 0.396742622 iYDR228C 0.397937963 0.435788262 0.627154444 "YDR229W -- unknown -- unknown function, possible coiled-coil protein" YDR305C HNT2 0.7 18 1.3 0.3606 0.820301117 iYDR305C 0.700953488 0.977850666 0.817806538 HNT2 -- unknown -- Diadenosine polyphosphate hydrolasemember of histidine triad (HIT) protein superfamily YDR376W ARH1 0.7 19 1.3 0.3606 0.403871284 iYDR375C 0.443588912 0.954353476 0.480622069 ARH1 -- unknown -- Mitochondrial similarity to human NAPDH-adrenodoxin reductase YER069W "ARG5,6" 0.7 20 1.3 0.3606 0.401899401 iYER068W 0.541362825 0.737436477 0.576861102 "ARG5,6 -- arginine biosynthesis -- Acetylglutamate kinase and N-acetyl-gamma-glutamyl-phosphate reductase, which catalyze the second and third steps of ornithine and arginine biosynthesis" YER079W YER079W 0.7 19 1.3 0.3606 0.186394291 iYER078C 0.250992565 0.213585671 0.05204461 YER079W -- unknown -- unknown function YGL014W YGL014W 0.7 19 1.3 0.3606 0.316583061 iYGL015C 0.10140639 0.899812638 0.247559894 YGL014W -- aging -- pumilio repeats that is involved with Mpt5p in relocalization of Sir3p and Sir4p from telomeres to the nucleolus YGL021W ALK1 0.7 20 1.3 0.3606 0.407541876 iYGL022W 0.254449999 0.567517957 0.128826942 ALK1 -- DNA repair (putative) -- DNA damage-responsive protein YGL067W NPY1 0.7 19 1.3 0.3606 0.71118666 iYGL068W 0.661935803 0.877954344 0.46488643 "NPY1 -- unknown -- NADH pyrophosphatase I of Nudix family of hydrolases, has a peroxisomal targeting signal" YHR058C MED6 0.7 20 1.3 0.3606 0.390582549 iYHR058C 0.337387051 0.701998051 0.171735097 MED6 -- transcription -- Component of RNA polymerase II holoenzyme and mediator subcomplex YHR161C YAP1801 0.7 17 1.3 0.3606 0.162366734 iYHR161C 0.018329448 0.585363873 0.112893936 YAP1801 -- endocytosis and secretion -- homologous to clathrin assembly polypeptide AP180interacts with Pan1p YKR021W YKR021W 0.7 18 1.3 0.3606 0.132665635 iYKR020W 0.137950729 0.496263808 0.274332545 YKR021W -- unknown -- unknown function YKR052C MRS4 0.7 18 1.3 0.3606 0.776381095 iYKR052C 0.54299716 0.991540445 0.710363873 "MRS4 -- transport -- Splicing protein and member of mitochondrial carrier (MCF) family, suppresses mitochondrial splicing defects" YLR059C REX2 0.7 19 1.3 0.3606 0.447395512 iYLR059C 0.530445635 0.579728651 0.336460133 "REX2 -- unknown -- Probable mitochondrial 3'-to-5' oligoribonuclease, suppressor of rna12/yme2 and yme1 rna12/yme2 mutations" YML064C TEM1 0.7 18 1.3 0.3606 0.979550061 iYML064C 0.985399771 0.80942977 0.525299282 "TEM1 -- cell cycle -- GTP-binding termination of M-phase, member of ras superfamily" YML065W ORC1 0.7 19 1.3 0.3606 0.601393423 iYML066C 0.52794502 0.284841808 0.407232704 "ORC1 -- DNA replication -- Subunit of origin recognition complex (ORC), related to the AAA+ family of S. cerevisae proteins" YML114C TAF65 0.7 18 1.3 0.3606 0.078485315 iYML114C 0.582617619 0.155620533 0.662809258 "TAF65 -- unknown -- Subunit of transcription factor TFIID, contains potential coiled-coil domain" YMR020W FMS1 0.7 18 1.3 0.3606 0.595099676 iYMR019W 0.300266351 0.652925204 0.057845799 FMS1 -- sterol metabolism (putative) -- similarity to Candida albicans corticosteroid-binding protein CBP1 YNL261W ORC5 0.7 20 1.3 0.3606 0.493966842 iYNL262W 0.311942105 0.876868096 0.405825722 "ORC5 -- DNA replication -- Origin recognition complex (ORC), 50 kDa subunit" YOR158W PET123 0.7 20 1.3 0.3606 0.424912989 iYOR157C 0.40757311 0.448414939 0.491702055 PET123 -- protein synthesis -- Mitochondrial ribosomal small subunit YPL125W KAP120 0.7 17 1.3 0.3606 0.459331796 iYPL126W 0.171466293 0.281683001 0.434372969 "KAP120 -- unknown -- Nuclear transport factor, member of karyopherin-beta family" YPL229W YPL229W 0.7 19 1.3 0.3606 0.078380635 iYPL230W 0.365314755 0.090512631 0.30626901 YPL229W -- unknown -- unknown function YBL014C RRN6 0.6 16 1.3 0.3606 0.575582421 iYBL014C 0.620692921 0.655307263 0.333951763 RRN6 -- transcription -- Component of RNA polymerase I core transcription factor (CF) along with Rrn7p and Rrn11p YBR167C POP7 0.6 16 1.3 0.3606 0.227608665 iYBR167C 0.377947818 0.226065688 0.486273554 "POP7 -- rRNA and tRNA processing -- Protein subunit of both RNase P and RNAse MRP, which are needed for tRNA processing and 5.8S rRNA processing, respectively" YDL177C YDL177C 0.6 17 1.3 0.3606 0.24149446 iYDL177C 0.433686453 0.273473034 0.417027496 YDL177C -- unknown -- unknown function YDR159W SAC3 0.6 16 1.3 0.3606 iYDR158W 0.670686684 0.600510162 "SAC3 -- leucine transport -- Nuclear leucine transport, mutants have defects in cytoskeletal functions and mitosis" YDR466W YDR466W 0.6 15 1.3 0.3606 0.506535682 iYDR465C 0.342592912 0.504948125 0.360569407 YDR466W -- unknown -- Serine/threonine protein kinase of unknown function YER059W PCL6 0.6 16 1.3 0.3606 0.684825221 iYER058W 0.422539242 0.84770509 0.216322913 PCL6 -- cell cycle -- Cyclin that associates with Pho85p YER161C SPT2 0.6 17 1.3 0.3606 0.027440022 iYER161C 0.15897685 0.0407058 0.012020793 "SPT2 -- chromatin structure -- HMG-like chromatin interacts with Snf1p through a conserved domain, negative regulator of HO gene transcription" YGL004C YGL004C 0.6 17 1.3 0.3606 0.388613368 iYGL004C 0.466893314 0.882774284 0.855100715 YGL004C -- unknown -- unknown function YGL095C VPS45 0.6 17 1.3 0.3606 0.705808962 iYGL095C 0.250978068 0.916280926 0.339831059 VPS45 -- vacuolar protein targeting -- Sec1p family essential for vacuolar protein sorting YGL116W CDC20 0.6 16 1.3 0.3606 0.97668881 iYGL117W 0.852009147 0.5320497 0.679357909 "CDC20 -- mitosis -- Activator of anaphase promoting complex (APC), required for microtubule function at mitosis and for exit from anaphase, contains WD (WD-40) repeats" YGL162W SUT1 0.6 15 1.3 0.3606 0.249484881 iYGL163C-0 iYGL163C-1 0.458805441 0.041964788 0.517066577 0.576458266 0.29260265 SUT1 -- transport -- sterol uptake YGL169W SUA5 0.6 14 1.3 0.3606 0.626274891 iYGL170C itK(CUU)G2 0.536029752 0.602557876 0.910381544 0.467934257 0.656134288 "SUA5 -- protein synthesis -- translation initiation, mutation suppresses the effect of an aberrant upstream ATG in CYC1" YGR116W SPT6 0.6 17 1.3 0.3606 0.705263572 0.60965195 SPT6 -- transcription -- chromatin structure that influences expression of many genes YHR023W MYO1 0.6 17 1.3 0.3606 0.600842511 iYHR022C 0.751141545 0.465097256 0.798644498 "MYO1 -- cell wall biosynthesis -- Myosin heavy chain (myosin II), coiled-coil septation and cell wall organization" YHR059W YHR059W 0.6 15 1.3 0.3606 0.201932097 iYHR058C 0.337387051 0.498244214 0.171735097 YHR059W -- unknown -- unknown function YIL002C INP51 0.6 16 1.3 0.3606 0.746037511 iYIL002C 0.885152857 0.54182911 0.724740623 INP51 -- phosphatidylinositol metabolism -- Inositol polyphosphate-5-phosphatase YJL127C SPT10 0.6 15 1.3 0.3606 0.214534488 iYJL127C 0.128573192 0.272705507 0.259417601 SPT10 -- transcription -- amplifies the magnitude of transcriptional regulation at various loci YJL197W UBP12 0.6 16 1.3 0.3606 0.223543424 iYJL198W 0.181953396 0.511046134 0.138228252 "UBP12 -- protein degradation, ubiquitin-mediated -- Ubiquitin-specific protease, ubiquitin C-terminal hydrolase" YJL213W YJL213W 0.6 16 1.3 0.3606 0.338837065 iYJL214W-0 iYJL214W-1 0.607878377 0.295693702 0.457764782 0.896169194 0.459387359 YJL213W -- unknown -- weak similarity to Nocardia aryldialkylphosphatase YKL183W YKL183W 0.6 17 1.3 0.3606 0.912120575 iYKL184W 0.512552252 0.872300999 0.291411537 YKL183W -- unknown -- unknown function YKR008W RSC4 0.6 17 1.3 0.3606 0.495981084 iYKR007W 0.247762397 0.726336792 0.086370255 RSC4 -- chromatin structure -- Component of abundant chromatin remodeling complex (RSC) YLL035W GRC3 0.6 16 1.3 0.3606 0.455931511 iYLL036C 0.302500206 0.530612245 0.597384665 "GRC3 -- unknown -- unknown function, interacts with Las1p" YLR057W YLR057W 0.6 16 1.3 0.3606 0.493210844 iYLR056W 0.656003897 0.649304715 0.841436485 YLR057W -- unknown -- unknown function YMR059W SEN15 0.6 16 1.3 0.3606 0.489507364 iYMR058W 0.573679556 0.708778931 0.403850901 "SEN15 -- tRNA splicing -- tRNA splicing endonuclease, delta subunit" YMR240C CUS1 0.6 16 1.3 0.3606 0.085701675 iYMR240C 0.190110411 0.260132774 0.163087304 "CUS1 -- mRNA splicing -- U2 snRNP protein, homolog of human SAP145" YNL029C KTR5 0.6 17 1.3 0.3606 0.693510466 0.486984626 KTR5 -- protein glycosylation -- Putative mannosyltransferase of KRE2 family YNL215W YNL215W 0.6 16 1.3 0.3606 0.037406076 iYNL216W 0.288464717 0.041727973 0.279648843 "YNL215W -- unknown -- unknown function, rich in glutamic acid residues" YNL272C SEC2 0.6 16 1.3 0.3606 0.4037841 iYNL272C 0.31633479 0.796009577 0.33530947 SEC2 -- secretion -- coiled-coil domain essential for vesicular transport to the plasma membrane YNL316C PHA2 0.6 15 1.3 0.3606 iYNL316C 0.64722969 0.204185374 "PHA2 -- phenylalanine biosynthesis -- Prephenate dehydratase, catalyzes a step in pathway of phenylalanine biosynthesis" YNR011C PRP2 0.6 15 1.3 0.3606 0.206884564 iYNR011C 0.2283917 0.462895702 0.426275332 "PRP2 -- mRNA splicing -- Pre-mRNA splicing factor and RNA-dependent ATPase of DEAH box family, required for first catalytic event of pre-mRNA splicing" YOL042W YOL042W 0.6 16 1.3 0.3606 0.344113428 iYOL043C 0.332445181 0.96618119 0.236392658 YOL042W -- unknown -- similarity to Ccr4p YOL043C NTG2 0.6 17 1.3 0.3606 0.318077015 iYOL043C 0.332445181 0.525942636 0.236392658 "NTG2 -- DNA repair -- Endonuclease III-like glycosylase/lyase 2, involved in DNA damage repair" YOL063C YOL063C 0.6 16 1.3 0.3606 0.439392495 iYOL063C 0.669624724 0.887069452 0.31219427 "YOL063C -- unknown -- unknown function, has WD (WD-40) repeats" YOR274W MOD5 0.6 16 1.3 0.3606 0.312604538 iYOR273C 0.509836178 0.438417191 0.749431449 MOD5 -- tRNA processing -- tRNA isopentenyltransferasecytoplasmic and mitochondrial forms have alternative translational start sites YOR390W YOR390W 0.6 16 1.3 0.3606 0.293571256 iYOR389W 0.244370828 0.226393812 0.336938155 YOR390W -- unknown -- unknown function YPL074W YTA6 0.6 17 1.3 0.3606 0.351815793 iYPL075W 0.166048954 0.239042862 0.121977835 "YTA6 -- unknown -- strong similarity to Yta4p, probable component of 26S proteasome complex, member of AAA family of ATPases" YPL100W YPL100W 0.6 17 1.3 0.3606 0.358566975 iYPL101W 0.364833645 0.295131684 0.136153232 YPL100W -- unknown -- similarity to Yfr021p YPR017C DSS4 0.6 16 1.3 0.3606 0.108214233 iYPR017C 0.095229418 0.178269686 0.06505848 DSS4 -- secretion -- Guanine-nucleotide exchange factor for Sec4p YPR104C FHL1 0.6 15 1.3 0.3606 0.641448828 iYPR104C 0.505809301 0.216886884 0.41475991 FHL1 -- transcription -- Transcriptional activator of forkhead/HNF3 family YBR001C NTH2 0.4 14 1.3 0.3606 0.631658907 iYBR001C 0.533704284 0.878746374 0.236716442 "NTH2 -- trehalose metabolism -- Putative secondary neutral trehalase (alpha, alpha-trehalase)" YDL050C YDL050C 0.4 11 1.3 0.3606 0.601821374 iYDL050C 0.63091067 0.515146632 0.521028037 YDL050C -- unknown -- unknown Functionquestionable ORF YDR147W EKI1 0.4 14 1.3 0.3606 0.503038132 iYDR146C 0.523000305 0.861821408 0.842679944 EKI1 -- phospholipid metabolism -- Ethanolamine kinase Ihas similarity to Cki1p choline kinase YDR157W 0.4 14 1.3 0.3606 YDR179W-A YDR179W-A 0.4 13 1.3 0.3606 0.411665547 iYDR179C 0.313181006 0.828216374 0.627699001 YDR179W-A -- unknown -- unknown function YDR198C YDR198C 0.4 12 1.3 0.3606 0.589076178 iYDR198C 0.364130876 0.81717024 0.258207631 YDR198C -- unknown -- unknown function YDR473C PRP3 0.4 14 1.3 0.3606 0.295437515 iYDR473C-0 iYDR473C-1 0.174539345 0.381428899 0.230649779 0.150580104 0.710866527 PRP3 -- mRNA splicing -- Pre-mRNA splicing factor required for stability of U4/U6 snRNPs and for assembly of U4/U6.U5 triplex snRNP particle from U4/U6 and U5 snRNPs YGR109C CLB6 0.4 13 1.3 0.3606 0.495565203 iYGR109C iYGRWsigma5 0.598915331 0.235308305 0.89179826 0.214912281 0.448180637 "CLB6 -- cell cycle -- B-type cyclin appearing late in G1, involved in initiation of DNA synthesis" YHL004W MRP4 0.4 13 1.3 0.3606 0.362076106 0.803818885 MRP4 -- protein synthesis -- Mitochondrial ribosomal small subunit (E. coli S2) YHR078W YHR078W 0.4 14 1.3 0.3606 0.445180257 iYHR077C 0.450036201 0.553443795 0.413712536 "YHR078W -- unknown -- unknown function, has 4 potential transmembrane segments" YIL005W YIL005W 0.4 12 1.3 0.3606 0.462036587 iYIL006W 0.205297467 0.632147498 0.411731844 "YIL005W -- unknown -- ER quality control, has similarity to disulfide isomerases" YJR034W PET191 0.4 13 1.3 0.3606 0.227796126 iYJR033C 0.573744102 0.51810922 0.329434541 PET191 -- respiration -- assembly of cytochrome oxidase YJR152W DAL5 0.4 14 1.3 0.3606 0.275347512 iYJR151C-0 iYJR151C-1 0.33763797 0.400780388 0.434653762 0.715237167 0.818788848 "DAL5 -- allantoin utilization -- Allantoate and ureidosuccinate permease, member of allantoate family of major facilitator superfamily (MFS)" YKL015W PUT3 0.4 12 1.3 0.3606 0.77736034 iYKL016C 0.917633344 0.768031189 0.790686432 PUT3 -- transcription -- Transcription factoractivates the proline utilization pathway genes and contains a Zn[2]-Cys[6] fungal-type binuclear cluster domain in the N-terminal region YKR037C SPC34 0.4 13 1.3 0.3606 0.306653529 iYKR037C 0.106701119 0.782468579 0.089432049 SPC34 -- cytoskeleton -- spindle pole body YKR083C YKR083C 0.4 14 1.3 0.3606 0.032996226 iYKR083C 0.574665335 0.065339994 0.28944028 YKR083C -- unknown -- similarity to paramyosin YLR451W LEU3 0.4 13 1.3 0.3606 0.439703927 iYLR450W 0.602835523 0.47947009 0.578965758 "LEU3 -- leucine biosynthesis -- Transcription factor regulating genes of branched chain amino acid biosynthesis pathways, acts as both a repressor and an inducer" YMR023C MSS1 0.4 14 1.3 0.3606 0.396705388 iYMR023C itA(AGC)M1 0.690856868 0.140912867 0.865694489 0.658878505 0.412277164 MSS1 -- protein synthesis (putative) -- Mitochondrial GTPase involved in expression of COX1/OXI3 YMR288W YMR288W 0.4 14 1.3 0.3606 0.298058997 iYMR287C 0.391978566 0.839622642 0.60745614 "YMR288W -- unknown -- U2 snRNP protein, homolog of human SAP155 U2 snRNP protein" YMR301C ATM1 0.4 12 1.3 0.3606 0.321371469 iYMR301C 0.522793005 0.851237031 0.62914921 "ATM1 -- transport -- Member of ATP-binding cassette (ABC) superfamily of membrane transporters, component of mitochondrial inner membrane" YNL273W TOF1 0.4 12 1.3 0.3606 0.094438913 iYNL274C 0.142126182 0.419435163 0.175347651 TOF1 -- unknown -- Topoisomerase I interacting factor YNR023W SNF12 0.4 13 1.3 0.3606 0.172888915 iYNR022C 0.472748721 0.51836932 0.259115035 "SNF12 -- transcription -- Component of SWI-SNF global transcription activator complex, acts to assist gene-specific activators through chromatin remodeling" YOL033W MSE1 0.4 14 1.3 0.3606 0.294603384 iYOL034W 0.70295655 0.53056664 0.421783626 "MSE1 -- protein synthesis -- Glutamyl-tRNA synthetase, mitochondrial" YOR191W RIS1 0.4 13 1.3 0.3606 0.330028162 iYOR190W 0.277391394 0.313486948 0.386883661 "RIS1 -- silencing -- silencing, member of Snf2p DNA-dependent ATPase family" YOR373W NUD1 0.4 14 1.3 0.3606 0.67471788 iYOR372C 0.053332244 0.228246858 0.02274204 NUD1 -- chromatin structure -- Spindle pole body nuclear division YPL042C SSN3 0.4 14 1.3 0.3606 0.290159845 iYPL042C 0.19039695 0.354817918 0.028134505 SSN3 -- transcription -- Cyclin-dependent serine/threonine protein kinase of RNA polymerase II holoenzyme complex and Kornberg's mediator (SRB) subcomplex YPL268W PLC1 0.4 12 1.3 0.3606 0.168343557 iYPL269W 0.141678356 0.375791986 0.009497207 "PLC1 -- signaling -- Phosphoinositide-specific phospholipase C (1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase 1), produces diacylglycerol and inositol 1,4,5-trisphosphate" YDR110W FOB1 0.3 11 1.3 0.3606 0.562658574 iYDR109C 0.804485891 0.271592008 0.070055905 FOB1 -- DNA replication(putative) -- blocking the replication fork and recombinational hotspot activity at the HOT1 site in rDNA YGR169C YGR169C 0.3 10 1.3 0.3606 0.516692786 iYGR169C 0.162408503 0.726975259 0.098736018 YGR169C -- unknown -- unknown function YGR233C PHO81 0.3 11 1.3 0.3606 0.481212585 iYGR233C-0 iYGR233C-1 0.815014959 0.576538491 0.665233862 0.645357663 0.824723847 "PHO81 -- cell cycle -- Cyclin-dependent kinase (CDK) inhibitor for Pho80p-Pho85p cyclin-dependent protein kinase complex, positive regulator of phosphate pathway" YJR050W ISY1 0.3 11 1.3 0.3606 0.471109665 iYJR049C 0.450950999 0.754477864 0.241260974 "ISY1 -- mRNA splicing -- Pre-mRNA splicing factor, required for optimal splicing in vivo" YJR147W HMS2 0.3 10 1.3 0.3606 0.579862813 0.252593775 HMS2 -- pseudohyphal growth -- Transcription factor with a probable role in pseudohyphal growth YKL072W STB6 0.3 10 1.3 0.3606 0.257338348 iYKL073W 0.566095323 0.521308859 0.497260715 STB6 -- unknown -- Protein which binds to Sin3p YKL132C RMA1 0.3 10 1.3 0.3606 0.317237963 0.855425601 RMA1 -- unknown; mating (putative) -- similarity to folylpolyglutamate synthaseconverts tetrahydrofolyl-[Glu(n)] + glutamate to tetrahydrofolyl-[Glu(n+1)] YNL333W SNZ2 0.3 10 1.3 0.3606 iYNL334C 0.489033723 0.192051345 "SNZ2 -- unknown -- Putative pyridoxine (vitamin B6) biosynthetic enzyme, member of stationary phase-induced gene family which includes Snz1p and Snz3p" YOL058W ARG1 0.3 9 1.3 0.3606 0.47639462 iYOL059W 0.461416237 0.469549084 0.258046302 ARG1 -- arginine biosynthesis -- Argininosuccinate synthetase (citrulline--aspartate ligase)catalyzes the penultimate step in arginine synthesis YPL067C YPL067C 0.3 10 1.3 0.3606 0.25216602 iYPL067C 0.474620106 0.845634823 0.53264166 YPL067C -- unknown -- unknown function YPL190C NAB3 0.8 24 1.2 0.3316 1 0.156170619 iYPL190C 0.933818228 0.079577219 0.302875244 NAB3 -- mRNA splicing -- Nuclear polyadenylated RNA-binding one RNA recognition (RRM) domain YJL025W RRN7 0.4 13 1.2 0.3316 1 0.49181337 iYJL026W 0.611654638 0.233126324 0.204511242 RRN7 -- transcription -- Component of RNA polymerase I core transcription factor (CF) along with Rrn6p and Rrn11p YER034W YER034W 0.4 13 1.2 0.3316 1 0.949420466 iYER033C 0.926078538 0.716448614 0.129172674 YER034W -- unknown -- unknown function YOR057W SGT1 0.4 15 1.2 0.3316 1 0.891694998 iYOR056C 0.96074641 0.573534151 "SGT1 -- mitosis (putative) -- Subunit of SCF ubiquitin ligase complex, essential for kinetochore assembly" YDR452W PHM5 1.9 61 1.2 0.3316 0.55377209 iYDR451C 0.329136315 0.648705332 0.476935355 "PHM5 -- unknown -- Vacuolar polyphosphatase, has similarity to human sphingomyelin phosphodiesterase PIR" YDL190C UFD2 1.8 55 1.2 0.3316 0.493967939 iYDL190C 0.555874255 0.93877551 0.897011046 "UFD2 -- protein degradation, ubiquitin-mediated -- Ubiquitin fusion degradation protein" YGL215W CLG1 1.7 49 1.2 0.3316 0.308386782 iYGL216W 0.534321129 0.187368973 0.331586303 "CLG1 -- cell cycle -- Cyclin-like protein, associates with Pho85p" YGR218W CRM1 1.3 42 1.2 0.3316 0.590011332 iYGR217W itG(GCC)G2 0.431416295 0.813369295 0.967932924 0.281165204 0.426284067 "CRM1 -- nuclear protein targeting -- Exportin, beta-karyopherin, functions in the export of certain proteins from the nucleus" YHR165C PRP8 1.2 38 1.2 0.3316 0.440036552 iYHR165C 0.240236703 0.22126224 0.063474178 "PRP8 -- mRNA splicing -- U5 snRNA-associated splicing factor, involved in association of U5 snRNP with U4/U6 snRNP and promotes both catalytic steps of splicing" YGL181W GTS1 1.1 35 1.2 0.3316 0.321906232 iYGL182C 0.614027371 0.85304544 0.636468362 "GTS1 -- heat shock, flocculation, and bud emergence -- Putative zinc-finger transcription factor of Gcs1p/Glo3p/Sps18p family, involved in heat resistance, flocculation, and timing of bud emergence" YGL247W YGL247W 1 30 1.2 0.3316 0.662454943 iYGL248W 0.242033554 0.859490815 0.177731228 YGL247W -- unknown -- unknown function YHL040C ARN1 1 30 1.2 0.3316 0.425111819 iYHL040C 0.347111402 0.46728972 0.598619846 "ARN1 -- unknown -- the transport of ferrichromes, member of yeast-specific putative multidrug-resistance family of major facilitator superfamily (MFS)" YKR100C YKR100C 1 32 1.2 0.3316 0.372838829 iYKR100C 0.45415606 0.50830008 0.399774139 YKR100C -- unknown -- unknown function YLR209C YLR209C 1 30 1.2 0.3316 0.519195904 iYLR209C 0.245839084 0.900298459 0.340225627 YLR209C -- unknown -- similarity to human purine nucleoside phosphorylase YNL118C DCP2 1 30 1.2 0.3316 0.286912861 iYNL118C 0.294260326 0.81099317 0.445617145 "DCP2 -- respiration (putative) -- Putative pyrophosphatase required with Dcp1p for mRNA decapping, suppresses the respiratory deficiency of a petite mutant" YBR165W UBS1 0.9 26 1.2 0.3316 0.511793938 iYBR164C 0.314041092 0.813008779 0.435949082 "UBS1 -- protein degradation, ubiquitin-mediated -- Positive regulator of Cdc34p" YBR269C YBR269C 0.9 27 1.2 0.3316 0.274524724 iYBR269C 0.691849611 0.620093804 0.449892986 YBR269C -- unknown -- unknown function YDR067C YDR067C 0.9 27 1.2 0.3316 0.561232135 iYDR067C 0.365215859 0.708266194 0.519933911 YDR067C -- unknown -- unknown function YGL261C YGL261C 0.9 29 1.2 0.3316 0.943014408 iYGL261C 0.911466841 0.756105347 0.448667966 YGL261C -- unknown -- Member of seripauperin (PAU) family YHR071W PCL5 0.9 29 1.2 0.3316 0.792474627 iYHR070W 0.376301438 0.870614035 0.19002063 PCL5 -- cell cycle -- Cyclin that associates with Pho85p YHR074W YHR074W 0.9 28 1.2 0.3316 0.491751062 iYHR073W 0.27393034 0.82528031 0.284181657 YHR074W -- unknown -- weak similarity to Rhodobacter protein adgA and Bacillus subtilis NH3-dependent NAD(+) synthetase (spore outgrowth factor) YLR206W ENT2 0.9 28 1.2 0.3316 0.153444357 iYLR205C 0.234169883 0.132482043 0.352638015 ENT2 -- endocytosis (putative) -- Epsin homolog required for endocytosis YLR298C YHC1 0.9 29 1.2 0.3316 0.301030353 iYLR298C 0.335212402 0.179483576 0.373981733 YHC1 -- mRNA splicing -- U1 snRNP similarity to human small ribonucleoprotein U1-C (snRNA-U1-C) YPR065W ROX1 0.9 27 1.2 0.3316 0.410603629 iYPR064W 0.563483274 0.143122677 0.428168105 "ROX1 -- transcription, oxygen-dependent -- Heme-dependent transcriptional repressor of hypoxic genes including CYC7 and ANB1" YCR075C ERS1 0.8 25 1.2 0.3316 0.288233533 iYCR075C 0.480906825 0.442495127 0.363778491 ERS1 -- secretion (putative) -- Suppressor of erd1 mutation YDL088C ASM4 0.8 24 1.2 0.3316 0.429160822 iYDL088C 0.564441083 0.391707671 0.449564937 ASM4 -- unknown -- Component of karyopherin docking complex of nuclear pore complexhas similarity to Nup53p YDL120W YFH1 0.8 25 1.2 0.3316 0.370325401 iYDL121C 0.587989388 0.265354619 0.862945493 "YFH1 -- iron homeostasis, mitochondrial -- Mitochondrial respiratory function and iron homeostasishomolog of human frataxin which is defective in Friedreich's ataxia" YDL123W YDL123W 0.8 26 1.2 0.3316 0.318809469 iYDL124W 0.214027268 0.482054583 0.110341332 YDL123W -- unknown -- unknown function YDR162C NBP2 0.8 24 1.2 0.3316 0.01932469 iYDR162C 0.131052719 0.169061171 0.20302467 "NBP2 -- unknown -- Nap1p-binding protein, has an SH3 domain" YER105C NUP157 0.8 23 1.2 0.3316 0.343532459 iYER105C 0.723079462 0.867531859 0.261490368 NUP157 -- nuclear protein targeting -- Nuclear pore protein (nucleoporin)has similarity to Nup170p and mammalian Nup155p YGR141W YGR141W 0.8 24 1.2 0.3316 0.500934267 iYGR140W 0.336387043 0.728710041 0.167201514 YGR141W -- unknown -- unknown function YGR222W PET54 0.8 23 1.2 0.3316 0.414520113 iYGR221C SNR7-L 0.557391218 0.734869784 0.56762699 0.49597164 0.620776478 PET54 -- protein synthesis -- Specific translational activator for mitochondrial COX3 mRNA and splicing factor for mitochondrial COX1 pre-mRNA YHL008C YHL008C 0.8 24 1.2 0.3316 0.434422813 iYHL008C 0.309160065 0.650178687 0.312515428 YHL008C -- unknown -- Member of formate-nitrite porter (FNP) family of membrane transporters YHR112C YHR112C 0.8 23 1.2 0.3316 0.347590646 iYHR112C 0.091854379 0.795117628 0.254695262 YHR112C -- unknown -- similarity to cystathionine gamma-synthase Str2p and other transulfuration enzymes YJR109C CPA2 0.8 25 1.2 0.3316 0.644833425 iYJR109C 0.55621808 0.889080885 0.606114383 "CPA2 -- glutamate metabolism -- Carbamoylphosphate synthase of arginine biosynthetic pathway, synthetase (large) subunit" YLR332W MID2 0.8 26 1.2 0.3316 0.061041127 0.062718379 MID2 -- mating (putative) -- Putative sensor for cell wall integrity signaling during vegetative growth and pheromone-induced morphorgenesis YMR031C YMR031C 0.8 24 1.2 0.3316 0.167298052 0.558956636 "YMR031C -- unknown -- unknown function, has potential coiled-coil region" YMR237W YMR237W 0.8 25 1.2 0.3316 0.511088944 iYMR236W 0.40290654 0.784402191 0.543676829 YMR237W -- unknown -- strong similarity to Bud7p YNL271C BNI1 0.8 26 1.2 0.3316 0.27221336 iYNL271C 0.298232379 0.175018514 0.145196418 "BNI1 -- bud site selection, bipolar -- cytoskeletal control and required for proper bipolar budding patterninteracts with Rho1p" YOR109W INP53 0.8 24 1.2 0.3316 0.237341746 iYOR108W 0.400649149 0.358926845 0.509115381 INP53 -- vesicle trafficking; phosphatidylinositol metabolism -- Dual functional inositol polyphosphate phosphatase YBL101W-A 0.7 21 1.2 0.3316 0.704793844 0.908858739 YBR024W SCO2 0.7 19 1.2 0.3316 0.300467624 iYBR023C 0.32998273 0.840233187 0.774252421 SCO2 -- respiration -- Protein possibly involved in stability of Cox1p and Cox2pparalog of Sco1p YBR056W YBR056W 0.7 22 1.2 0.3316 0.721791037 iYBR055C itL(UAA)B2 0.667293685 0.81328513 0.83056664 0.450108897 0.648842777 "YBR056W -- unknown -- similarity to glucan-1,3-beta-glucosidase (exo-1,3-beta-glucanase)" YBR103W EMB1 0.7 21 1.2 0.3316 0.282377575 iYBR102C 0.469862486 0.76351808 0.425519818 "EMB1 -- unknown -- telomere silencing, interacts with Sir4p and targets Sir4p from telomeres to other sites, has WD (WD-40) repeats" YBR120C CBP6 0.7 20 1.2 0.3316 0.61994166 iYBR120C 0.403544593 0.72043184 0.434571513 "CBP6 -- protein synthesis, COB -- Translational activator of COB mRNA" YBR202W CDC47 0.7 21 1.2 0.3316 0.5806012 iYBR201W-0 iYBR201W-1 0.284230997 0.497121728 0.608512021 0.397536688 0.539082036 CDC47 -- DNA replication -- Member of MCM/P1 family of proteins involved in DNA synthesis initiation YDL224C WHI4 0.7 19 1.2 0.3316 0.281909057 iYDL224C 0.680673438 0.420565302 0.463128492 WHI4 -- cell size -- cell size determination YDR111C YDR111C 0.7 19 1.2 0.3316 0.866587636 0.97556159 YDR111C -- unknown -- Putative alanine aminotransferase YDR163W YDR163W 0.7 20 1.2 0.3316 0.109982811 iYDR162C 0.131052719 0.208140463 0.20302467 YDR163W -- unknown -- unknown function YDR463W STP1 0.7 21 1.2 0.3316 0.647424045 iYDR462W 0.550026752 0.822262571 0.525288376 "STP1 -- tRNA splicing -- Zinc finger pre-tRNA splicing of specific tRNA species, has three C2H2-type zinc fingers" YFR041C YFR041C 0.7 22 1.2 0.3316 0.507770875 iYFR041C 0.053262101 0.931042669 0.028102664 "YFR041C -- unknown -- weak similarity to dnaJ proteins Sis1p, Mdj1p, and Scj1p" YHR054C YHR054C 0.7 22 1.2 0.3316 0.684085487 iYHR054C 0.313099692 0.956927313 0.298539969 "YHR054C -- unknown -- unknown function, coded from the CUP1A and CUP1B repeat region" YIL007C YIL007C 0.7 19 1.2 0.3316 0.277746204 iYIL007C 0.226800462 0.375464684 0.417103424 YIL007C -- unknown -- similarity to human proteosomal modulator subunit p27 YJR005W APL1 0.7 19 1.2 0.3316 0.579533453 iYJR004C 0.171166683 0.900399042 0.487573099 "APL1 -- secretion -- Beta-adaptin, large subunit of clathrin-associated protein (AP) complex" YKR007W YKR007W 0.7 20 1.2 0.3316 0.155288483 iYKR006C 0.01777473 0.261514883 0.001117318 YKR007W -- unknown -- unknown function YLR107W REX3 0.7 22 1.2 0.3316 0.602655514 iYLR106C 0.726183777 0.85391627 0.5132723 "REX3 -- unknown -- RNA exonuclease, member of family of 3' -5' exonucleases" YLR191W PEX13 0.7 21 1.2 0.3316 0.292306456 iYLR190W 0.164683523 0.619393456 0.610457622 "PEX13 -- peroxisomal protein targeting -- Peroxisomal biogenesis protein (peroxin) that serves as a docking target for the PTS1 receptor Pex5p, has an SH3 domain" YMR222C YMR222C 0.7 23 1.2 0.3316 0.573164438 iYMR222C 0.604416095 0.827344505 0.768127618 "YMR222C -- unknown -- similarity to S. pombe DFR1, dihydrofolate reductase" YOR171C LCB4 0.7 21 1.2 0.3316 0.701194906 iYOR171C 0.250350689 0.846197228 0.280838121 "LCB4 -- sphingolipid metabolism -- Long chain base kinase, involved in sphingolipid metabolism" YPR046W MCM16 0.7 22 1.2 0.3316 0.2603766 iYPR045C 0.503092843 0.665020982 0.254264993 "MCM16 -- mitosis,chromosome segregation -- chromosome segregation" YPR178W PRP4 0.7 20 1.2 0.3316 0.070664043 0.362068966 "PRP4 -- mRNA splicing -- U4/U6 snRNA-associated splicing factor, member of WD (WD-40) repeat family" YAL027W YAL027W 0.6 18 1.2 0.3316 0.779401484 iYAL028W 0.381734902 0.89755586 0.738060429 YAL027W -- unknown -- unknown function YBR028C YBR028C 0.6 17 1.2 0.3316 0.20844146 iYBR028C 0.443607117 0.469217024 0.418304866 YBR028C -- unknown -- Serine/threonine protein kinase with similarity to Ypk2p/Ykr2p and Ypk1p YBR107C IML3 0.6 16 1.2 0.3316 0.702548436 iYBR107C 0.493075036 0.958818835 0.400466693 "IML3 -- mitosis, chromosome segregation (putative) -- minichromosome maintenance" YBR222C FAT2 0.6 17 1.2 0.3316 0.623080587 iYBR222C 0.531057243 0.913647247 0.871575894 FAT2 -- transport -- Peroxisomal AMP-binding protein YCR058C PWP2 0.6 17 1.2 0.3316 "PWP2 -- -- Periodic tryptophan protein, has eight WD (WD-40) repeats" YCR102C YCR102C 0.6 18 1.2 0.3316 0.241893521 iYCR102C YCR102W-A 0.542474968 0.785609278 0.531904608 0.794972067 0.334187852 YCR102C -- unknown -- similarity to B subtilis sorbitol dehydrogenase YDR128W YDR128W 0.6 18 1.2 0.3316 0.205500127 iYDR127W 0.307278328 0.31888495 0.832018653 "YDR128W -- unknown -- unknown function, has WD (WD-40) repeats" YDR306C YDR306C 0.6 16 1.2 0.3316 0.472535934 iYDR306C tV(CAC)D 0.412145542 0.71077957 0.820044433 0.629988351 0.359538784 "YDR306C -- unknown -- unknown function, contains an F-box" YDR318W MCM21 0.6 17 1.2 0.3316 0.271616826 iYDR317W 0.137791919 0.419567185 0.65098292 "MCM21 -- mitosis, chromosome segregation -- Component of centromere/kinetochore-associated protein network" YDR430C YDR430C 0.6 16 1.2 0.3316 YDR430C -- unknown -- unknown function YDR456W NHX1 0.6 18 1.2 0.3316 0.348403446 0.868192072 NHX1 -- transport -- Late endosomal Na+/H+ antiporter YER024W YER024W 0.6 17 1.2 0.3316 0.329488882 iYER023W 0.377240509 0.703947368 0.334193757 YER024W -- unknown -- similarity to Yat1p YGL145W TIP20 0.6 17 1.2 0.3316 0.771011302 iYGL146C 0.449903617 0.942894758 0.267080745 TIP20 -- secretion -- Cytoplasmic ER to Golgi transportinteracts physically with Sec20p YGL190C CDC55 0.6 18 1.2 0.3316 0.559725908 iYGL190C 0.500361325 0.671377518 0.134952005 "CDC55 -- cell cycle -- Protein serine/threonine phosphatase 2A (PP2A) regulatory subunit B, ceramide-activated protein phosphatase B subunit, has WD (WD-40) repeats" YHR158C KEL1 0.6 16 1.2 0.3316 0.372909232 iYHR158C 0.133325513 0.291142558 0.172169811 "KEL1 -- unknown -- cell fusion and morphology, contains six Kelch repeats" YIL161W YIL161W 0.6 18 1.2 0.3316 0.153608833 iYIL162W 0.21772163 0.104775828 0.093567251 YIL161W -- unknown -- unknown function YJR130C STR2 0.6 18 1.2 0.3316 0.660145076 iYJR130C 0.333205915 0.815098292 0.353070175 "STR2 -- unknown -- Cystathionine gamma-synthase, part of C3 to C4 transsulfurylation pathway" YJR142W YJR142W 0.6 16 1.2 0.3316 0.555278554 iYJR141W 0.687334137 0.736598441 0.501369642 "YJR142W -- unknown -- unknown function, has similarity to a portion of S. pombe thiamine pyrophosphokinase" YKL034W YKL034W 0.6 16 1.2 0.3316 0.589706591 iYKL035W 0.195256982 0.895746052 0.177152901 YKL034W -- unknown -- unknown function YKR016W YKR016W 0.6 17 1.2 0.3316 0.299391123 iYKR015C 0.300065338 0.658438246 0.341211583 YKR016W -- unknown -- Protein possibly involved in respiration YLR157C ASP3B 0.6 18 1.2 0.3316 0.442412329 iYLR157C-0 iYLR157C-A 0.115133078 0.153616966 0.800032489 0.432389937 0.213727055 "ASP3B -- asparagine utilization -- L-asparaginase II, extracellular" YLR205C YLR205C 0.6 17 1.2 0.3316 0.119155041 iYLR205C 0.234169883 0.669678148 0.352638015 "YLR205C -- unknown -- unknown function, induced during aerobic growth" YLR215C YLR215C 0.6 17 1.2 0.3316 0.203164908 iYLR215C 0.719597615 0.525781502 0.548049582 YLR215C -- unknown -- unknown function YLR418C CDC73 0.6 17 1.2 0.3316 0.395068601 iYLR418C 0.338867449 0.708302477 0.475273595 CDC73 -- transcription -- RNA polymerase II accessory protein YMR199W CLN1 0.6 17 1.2 0.3316 0.402212517 iYMR198W 0.106701993 0.423383879 0.345310989 CLN1 -- cell cycle -- G1/S-specific cyclin that interacts with Cdc28p protein kinase to control events at START YNL076W MKS1 0.6 18 1.2 0.3316 0.18838188 iYNL077W 0.426987087 0.532790191 0.246605776 "MKS1 -- signaling, Ras pathway -- Negative regulator of Ras-cAMP pathway and of lysine biosynthesis pathway, involved in nitrogen regulation" YNL150W YNL150W 0.6 16 1.2 0.3316 0.932913828 iYNL151C 0.901574989 0.281838856 0.251013923 YNL150W -- unknown -- unknown function YNL222W SSU72 0.6 18 1.2 0.3316 0.646924228 iYNL223W 0.310289326 0.920327813 0.371783496 SSU72 -- transcription -- interacts with TFIIB (Sua7p) and influences RNA polymerase II start-site selection in sua7 mutants YNL236W SIN4 0.6 18 1.2 0.3316 0.54059131 iYNL237W 0.425346894 0.612948833 0.326656026 SIN4 -- transcription -- Component of RNA polymerase II holoenzyme and Kornberg's mediator subcomplexhas positive and negative effects on transcription of individual genes YNL257C SIP3 0.6 16 1.2 0.3316 0.462450272 iYNL257C 0.471601746 0.567278532 0.376058724 "SIP3 -- glucose derepression -- interacts with Snf1p, contains a PH (pleckstrin homology) domain" YOR118W YOR118W 0.6 17 1.2 0.3316 0.205550915 iYOR117W 0.440503583 0.105100715 0.693764099 YOR118W -- unknown -- unknown function YOR269W PAC1 0.6 19 1.2 0.3316 0.584669576 iYOR268C 0.881708208 0.57054126 0.349036057 "PAC1 -- cytoskeleton (putative) -- Protein required in the absence of Cin8p, contains WD (WD-40) repeats" YOR352W YOR352W 0.6 16 1.2 0.3316 0.297505935 iYOR351C 0.193993972 0.521753142 0.352673583 YOR352W -- unknown -- unknown function YPL022W RAD1 0.6 17 1.2 0.3316 0.391570238 iYPL023C 0.082992882 0.243798043 0.068240413 "RAD1 -- DNA repair, nucleotide excision -- Component of nucleotide excision repairosome, homolog of human XPF xeroderma pigmentosum gene product and the mammalian ERCC-4 protein" YPL104W MSD1 0.6 17 1.2 0.3316 0.162819437 iYPL105C 0.525070017 0.249253852 0.77047087 "MSD1 -- protein synthesis -- Aspartyl-tRNA synthetase, mitochondrial" YPR019W CDC54 0.6 17 1.2 0.3316 0.213469533 iYPR018W 0.548239602 0.418891517 0.252255881 "CDC54 -- DNA replication -- Member of MCM family of proteins, involved in DNA synthesis initiation" YAL041W CDC24 0.4 16 1.2 0.3316 0.705196697 iYAL042W 0.185700683 0.932242618 0.115252792 "CDC24 -- cell polarity -- GTP-GDP exchange factor for Cdc42p, involved in bud emergence, bud site selection and formation of mating projection (shmoo)" YAR071W PHO11 0.4 12 1.2 0.3316 0.77796665 iYAR070C 0.677761128 0.935224536 0.561670161 "PHO11 -- phosphate metabolism -- Acid phosphatase, secreted" YBL059W YBL059W 0.4 15 1.2 0.3316 0.82965441 iYBL060W 0.790048334 0.975541579 0.858731606 YBL059W -- unknown -- unknown function YBR270C YBR270C 0.4 15 1.2 0.3316 0.138138929 iYBR270C 0.335562457 0.757891282 0.676974144 "YBR270C -- unknown -- unknown function, probable ATP/GTP-binding protein" YDR416W SYF1 0.4 15 1.2 0.3316 0.943419136 iYDR415C 0.328634104 0.665967573 0.17382949 "SYF1 -- cell cycle (putative) -- Pre-mRNA splicing factor with similarity to Drosophila crn protein, has tetratricopeptide (TPR) repeats" YDR528W YDR528W 0.4 14 1.2 0.3316 0.544073905 iYDR527W-0 iYDR527W-1 0.382036669 0.543041243 0.749280013 0.489954577 0.692258579 YDR528W -- unknown -- unknown function YEL025C SRI1 0.4 15 1.2 0.3316 0.624572866 iYEL025C 0.596573841 0.603129789 0.571891498 SRI1 -- unknown -- unknown function YER111C SWI4 0.4 13 1.2 0.3316 0.443887199 iYER111C 0.415947846 0.425751223 0.683123509 "SWI4 -- cell cycle -- Transcription factor that participates in the SBF complex (Swi4p-Swi6p) for regulation at the cell cycle box (CCB) element, has 2 ankyrin repeats" YER147C YER147C 0.4 14 1.2 0.3316 0.416313829 iYER147C 0.236231547 0.762492326 0.028589994 YER147C -- unknown -- sister chromatid cohesion YER166W YER166W 0.4 15 1.2 0.3316 0.681205835 iYER165W 0.54467973 0.562681276 0.769658395 YER166W -- unknown -- Members of Drs2p family of P-type ATPase superfamily YGL108C YGL108C 0.4 16 1.2 0.3316 0.063418649 iYGL108C 0.503383966 0.035355148 0.232374919 YGL108C -- unknown -- unknown function YHR116W YHR116W 0.4 12 1.2 0.3316 0.048971865 iYHR115C 0.197197223 0.091107617 0.286595902 YHR116W -- unknown -- unknown function YHR204W YHR204W 0.4 15 1.2 0.3316 0.943898677 iYHR203C 0.992944654 0.759958071 0.614663046 YHR204W -- unknown -- similarity to alpha-mannosidase and other glycosyl hydrolases YIL001W YIL001W 0.4 15 1.2 0.3316 0.773544406 iYIL002C 0.885152857 0.93981234 0.724740623 "YIL001W -- unknown -- unknown function, contains two BTB/POZ domains" YIL093C YIL093C 0.4 16 1.2 0.3316 0.699829598 iYIL093C 0.201256967 0.335637291 0.181124107 YIL093C -- unknown -- unknown function YIL128W MET18 0.4 15 1.2 0.3316 0.798262304 iYIL129C 0.148920465 0.971611948 0.144221021 MET18 -- transcription and DNA repair -- nucleotide excision repair and transcription by RNA polymerase II YIL137C YIL137C 0.4 15 1.2 0.3316 0.405071285 iYIL137C 0.476723293 0.842941999 0.559429836 YIL137C -- unknown -- similarity to aminopeptidases YIR024C GIF1 0.4 15 1.2 0.3316 0.181383657 iYIR024C 0.066132427 0.386127355 0.112387508 "GIF1 -- cell cycle, G1 -- normal G1 phase of cell cycle" YJL076W NET1 0.4 15 1.2 0.3316 0.593134496 iYJL077C 0.489889409 0.21814985 0.392619718 "NET1 -- silencing -- Nucleolar rDNA chromatin silencing and nucleolar integrity, has similarity to Tof2p" YJL156C SSY5 0.4 13 1.2 0.3316 0.360819447 iYJL156C 0.310848604 0.566914498 0.152536904 "SSY5 -- transport, amino acid (putative) -- sulfonylurea herbicide sensitivity" YKL011C CCE1 0.4 15 1.2 0.3316 0.611095789 iYKL011C 0.666801981 0.581914979 0.520929198 CCE1 -- tRNA processing -- Cruciform cutting endonuclease YKR036C CAF4 0.4 13 1.2 0.3316 0.147100945 iYKR036C 0.236023057 0.514863548 0.293426833 "CAF4 -- catabolite repression -- associates with Ccr4p, contains WD (WD-40) repeats" YLL001W DNM1 0.4 16 1.2 0.3316 0.874002315 iYLL002W 0.89446324 0.850058333 0.676137271 DNM1 -- endocytosis -- Dynamin-related controls morphology and cortical localization of mitochondria YLL061W MMP1 0.4 15 1.2 0.3316 0.342503696 iYLL062C 0.193930662 0.533699905 0.391179453 "MMP1 -- transport, amino acid -- High affinity S-methylmethionine permease, has similarity to Gap1p and other amino acid permeases" YLR026C SED5 0.4 14 1.2 0.3316 0.282973529 iYLR026C 0.290716437 0.356268128 0.17905044 SED5 -- secretion -- Syntaxin homolog (t-SNARE) required in ER to Golgi transportfound on Golgi membrane which receives transport vesicles YLR082C SRL2 0.4 13 1.2 0.3316 0.412012054 iYLR082C 0.429860652 0.787597161 0.598743212 SRL2 -- unknown -- unknown function YML076C YML076C 0.4 13 1.2 0.3316 0.249253262 iYML076C 0.92632905 0.223925143 0.986373729 "YML076C -- unknown -- similarity to transcription factors, has Zn[2]-Cys[6] fungal-type binuclear cluster domain in the N-terminal region" YMR119W YMR119W 0.4 13 1.2 0.3316 0.476867282 iYMR118C YMRWdelta16 0.595212409 0.764073371 0.711005479 0.750100831 0.861111111 YMR119W -- unknown -- unknown function YMR268C PRP24 0.4 13 1.2 0.3316 0.367951276 iYMR268C 0.105213645 0.453711093 0.093697195 "PRP24 -- mRNA splicing -- Pre-mRNA splicing factor, responsible for reannealing U4 and U6 snRNAs to recycle snRNPs for subsequent splicing reactions, has 3 RNA recognition (RRM) domains" YMR294W JNM1 0.4 15 1.2 0.3316 0.231932873 iYMR293C 0.629314857 0.371541502 0.271189172 "JNM1 -- mitosis, nuclear migration -- Coiled-coil nuclear migration and control of astral microtubules during mitotic growth" YNL142W MEP2 0.4 14 1.2 0.3316 0.201389164 iYNL143C 0.480464131 0.211013645 0.277809147 MEP2 -- transport -- Ammonia permease of low capacity and high affinity YNL174W YNL174W 0.4 15 1.2 0.3316 0.602942359 0.651467505 YNL174W -- unknown -- unknown function YNL225C CNM67 0.4 15 1.2 0.3316 0.36826968 iYNL225C 0.425945343 0.433263452 0.404175402 CNM67 -- cytoskeleton -- nuclear migration and component of spindle pole body YOR038C HIR2 0.4 12 1.2 0.3316 0.219698911 iYOR038C 0.07715158 0.573261858 0.275331936 "HIR2 -- transcription -- Histone transcription regulator, required for periodic repression of 3 of 4 histone gene loci and for autogenous repression of HTA1-HTB1 locus by H2A and H2B" YOR328W PDR10 0.4 14 1.2 0.3316 0.122161099 iYOR327C 0.135793801 0.298895387 0.366563715 PDR10 -- transport -- Member of ATP-binding cassette (ABC) superfamily YPR071W YPR071W 0.4 12 1.2 0.3316 0.631371869 iYPR070W 0.67649461 0.410818713 0.8202791 "YPR071W -- unknown -- unknown function, has similarity to Yil029p" YBR074W YBR074W 0.3 12 1.2 0.3316 0.387022775 iYBR073W 0.730148491 0.707843321 0.363425295 YBR074W -- unknown -- similarity to Ape3p YBR093C PHO5 0.3 12 1.2 0.3316 0.804393989 iYBR093C 0.464398798 0.954263128 0.545297457 "PHO5 -- phosphate metabolism -- Acid phosphatase, repressible, requires glycosylation for activity" YDL129W YDL129W 0.3 11 1.2 0.3316 0.7331025 iYDL130W 0.83319409 0.669022092 0.446391837 YDL129W -- unknown -- unknown function YEL076C YEL076C 0.3 12 1.2 0.3316 0.896867284 0.13990423 YEL076C -- unknown -- similarity to other subtelomerically-encoded proteins YFR025C HIS2 0.3 9 1.2 0.3316 0.523139965 iYFR025C itA(AGC)F 0.163110144 0.548065022 0.927294493 0.091960333 0.749257141 HIS2 -- histidine biosynthesis -- Histidinol phosphatase YGR040W KSS1 0.3 11 1.2 0.3316 0.779844685 iYGR039W 0.271976688 0.971076378 "KSS1 -- pheromone signal transduction -- Serine/threonine protein kinase involved in the filamentous and invasive growth pathway, member of MAP kinase family" YJR079W YJR079W 0.3 11 1.2 0.3316 0.530302814 IntYJR079W 0.370067241 0.870231445 0.716613182 YJR079W -- unknown -- unknown function YJR131W MNS1 0.3 12 1.2 0.3316 0.840081842 iYJR130C 0.333205915 0.732740887 0.353070175 "MNS1 -- protein glycosylation -- Alpha-mannosidase, specific for removal of one mannose from Man[9]GlcNac to produce a single isomer of Man[8]GlcNac" YKL158W YKL158W 0.3 11 1.2 0.3316 0.626213906 iYKL159C 0.258157263 0.923292782 0.238731656 YKL158W -- unknown -- unknown function YLR081W GAL2 0.3 9 1.2 0.3316 0.319882388 iYLR080W 0.464357613 0.780511414 0.76466716 "GAL2 -- transport -- Galactose (and glucose) permease (facilitated diffusion transporter), member of hexose transporter family of major facilitator superfamily (MFS)" YNL049C SFB2 0.3 12 1.2 0.3316 0.265038803 iYNL049C 0.304094532 0.587351502 0.434789764 "SFB2 -- unknown -- similarity to Sec24p, has a redundant role with Sec24p in transport vesicle formation from the endoplasmic reticulum" YNL299W TRF5 0.3 11 1.2 0.3316 0.207603041 iYNL300W 0.639047059 0.228890662 0.129608939 TRF5 -- mitosis -- functionally similar to DNA topoisomerase I YPR056W TFB4 0.3 13 1.2 0.3316 0.869176152 iYPR055W 0.665361048 0.865854642 0.603351955 "TFB4 -- transcription -- RNA polymerase II transcription initiation factor TFIIH (factor b), 37 kDa subunit" YNL304W YPT11 0.2 8 1.2 0.3316 0.276543613 iYNL305C 0.063767623 0.434701944 0.070517568 "YPT11 -- signaling (putative) -- unknown function, member of rab family in the ras superfamily of small GTP-binding proteins" YOL060C AMI3 0.7 22 1.1 0.3025 1 0.857125278 iYOL060C 0.995398953 0.097969707 0.633863031 AMI3 -- mitochondrial morphology (putative) -- normal mitochondrial structure YDR301W CFT1 0.6 18 1.1 0.3025 1 0.662098002 iYDR300C 0.980802672 0.592732839 0.225183916 CFT1 -- mRNA 3'-end processing -- Component of pre-mRNA cleavage factor II YER045C YER045C 0.6 19 1.1 0.3025 1 0.190531142 iYER045C-0 iYER045C-1 0.939890272 0.95689995 0.135721248 0.762335248 0.764644852 "YER045C -- unknown -- unknown function, has a predicted basic leucine zipper (bZIP) DNA-binding domain" YNL325C FIG4 0.4 14 1.1 0.3025 1 0.994607179 0.046728972 FIG4 -- mating (putative) -- Suppressor of sac1 mutation and protein induced by mating factor YER168C CCA1 0.4 16 1.1 0.3025 1 0.950615115 iYER168C 0.941527414 0.94574399 0.062031137 "CCA1 -- tRNA processing -- tRNA nucleotidyltransferase (tRNA CCA-pyrophosphorylase), carries out addition of CCA to 3' end without a template" YJL029C VPS53 0.4 13 1.1 0.3025 1 0.730630518 iYJL029C itM(CAU)J1 0.87415968 0.939603142 0.778691141 0.572799871 0.589360587 "VPS53 -- unknown -- Subunit of Vps52p-Vps53p-Vps54p complex, involved in protein sorting in the late Golgi" YMR013C SEC59 0.4 14 1.1 0.3025 1 0.988382946 iYMR013C-0 iYMR013C-1 0.987984505 0.987123058 0.944129022 0.107891179 0.264872871 "SEC59 -- protein glycosylation -- Dolichol kinase, mutants accumulate incompletely glycosylated protein precursors in ER" YNL201C YNL201C 0.3 12 1.1 0.3025 1 0.332960232 iYNL201C 0.921252686 0.41811652 0.61375792 YNL201C -- unknown -- regulation of carbon metabolism YCR011C ADP1 1.3 45 1.1 0.3025 0.471317167 iYCR011C 0.746110646 0.41348763 0.217247335 ADP1 -- transport -- Membrane transporter of ATP-binding cassette (ABC) superfamily YLR225C YLR225C 1.3 43 1.1 0.3025 0.091957755 iYLR225C 0.445695857 0.608244878 0.358604576 YLR225C -- unknown -- unknown function YCR067C SED4 1.1 38 1.1 0.3025 0.453270264 iYCR067C 0.509386272 0.571312541 0.288108282 "SED4 -- secretion -- vesicle formation in the endoplasmic reticulum, has HDEL ER-retention sequence that is unusual for a membrane protein" YHR028C DAP2 1 32 1.1 0.3025 0.830472311 iYHR028C 0.407376827 0.880590496 0.48838225 DAP2 -- protein degradation -- Dipeptidyl aminopeptidase B YGR032W GSC2 0.9 30 1.1 0.3025 0.577565997 iYGR031W 0.869606042 0.416693522 0.24880925 "GSC2 -- cell wall biogenesis -- Component of beta-1,3-glucan synthase, probably functions as an alternate subunit with Fks1p with which is has strong similarity" YIL125W KGD1 0.9 29 1.1 0.3025 0.509667663 iYIL126W 0.351787865 0.947086991 0.409937888 KGD1 -- respiration -- 2-Oxoglutarate dehydrogenase complex E1 component YBR293W YBR293W 0.8 27 1.1 0.3025 0.483026557 iYBR292C-0 iYBR292C-1 0.264057175 0.62939143 0.645630279 0.416103413 0.651949726 YBR293W -- unknown -- Member of multidrug-resistance (MDR) 14-spanner family of major facilitator superfamily (MFS) YDR479C YDR479C 0.8 26 1.1 0.3025 0.485409095 iYDR479C 0.098575959 0.855588044 0.226656026 YDR479C -- unknown -- unknown function YDR505C PSP1 0.8 25 1.1 0.3025 0.527822086 iYDR505C 0.235160479 0.603966099 0.244234801 PSP1 -- unknown -- High-copy suppressor of temperature sensitive mutations in Cdc17p DNA polymerase alpha YEL049W PAU2 0.8 26 1.1 0.3025 0.91502319 iYEL050C SNR67 0.716215544 0.84668702 0.425838574 0.705538085 0.6632083 PAU2 -- unknown -- Member of seripauperin (PAU) family YFR039C YFR039C 0.8 27 1.1 0.3025 0.516170737 iYFR039C 0.164040776 0.839187883 0.168534763 YFR039C -- unknown -- unknown function YGL203C KEX1 0.8 26 1.1 0.3025 0.327205335 iYGL203C iYGLWdelta3 0.530542452 0.772277815 0.436871508 0.469054581 0.78371768 "KEX1 -- secretion -- Carboxypeptidase specific for C-terminal Arg or Lys, involved in processing precursors of alpha-factor and K1 and K2 killer toxins" YIR041W YIR041W 0.8 25 1.1 0.3025 0.939605273 iYIR040C 0.894784592 0.527715114 0.37394412 YIR041W -- unknown -- Member of seripauperin (PAU) family YKL100C YKL100C 0.8 25 1.1 0.3025 0.830110725 iYKL100C 0.550226588 0.940702314 0.181516422 YKL100C -- unknown -- unknown function YMR211W YMR211W 0.8 25 1.1 0.3025 0.205832006 iYMR210W 0.429835785 0.548918554 0.373917302 YMR211W -- unknown -- weak similarity to beta-tubulins YBR229C ROT2 0.7 22 1.1 0.3025 0.442268274 iYBR229C 0.158321882 0.704460967 0.111875267 ROT2 -- cytoskeleton -- Catalytic (alpha) subunit of glucosidase II YDL056W MBP1 0.7 24 1.1 0.3025 0.580614718 iYDL057W 0.243586925 0.440237794 0.563766597 "MBP1 -- cell cycle -- Transcription factor that collaborates with Swi6p to form the MBF (Mbp1p-Swi6p) factor for regulation at Mlu1 cell cycle box (MCB) elements, has two ankyrin repeats" YDR307W YDR307W 0.7 21 1.1 0.3025 0.22170866 iYDR306C tV(CAC)D 0.412145542 0.71077957 0.703750998 0.629988351 0.359538784 YDR307W -- unknown -- similarity to Pmt1p YDR329C PEX3 0.7 25 1.1 0.3025 0.281212759 iYDR329C 0.160377593 0.646366056 0.189500535 PEX3 -- peroxisomal protein targeting -- Peroxisomal biogenesis protein YFL013C YFL013C 0.7 21 1.1 0.3025 0.695546751 0.414160189 YFL013C -- unknown -- weak similarity to Ifh1p and Nab3p YFR042W YFR042W 0.7 22 1.1 0.3025 0.464313733 iYFR041C 0.053262101 0.733752621 0.028102664 YFR042W -- unknown -- unknown function YGR223C YGR223C 0.7 22 1.1 0.3025 0.434436008 iYGR223C 0.253309916 0.900943777 0.24715657 YGR223C -- unknown -- unknown function YHL007C STE20 0.7 23 1.1 0.3025 0.509871764 iYHL007C 0.161802338 0.729288499 0.112979207 "STE20 -- signaling, pheromone and pseudohyphal growth pathways -- Serine/threonine protein kinase of pheromone response pathway, also participates in the filamentous growth and STE vegetative growth pathways" YHR194W YHR194W 0.7 22 1.1 0.3025 0.225316182 iYHR193C 0.895875186 0.830887491 0.217049679 YHR194W -- unknown -- unknown function YIL149C MLP2 0.7 22 1.1 0.3025 0.686578445 iYIL149C 0.985554147 0.447314083 0.599821313 "MLP2 -- unknown -- associated with the nuclear pore complex, with similarity to Mlp1p and myosin heavy chains, has potential coiled-coil domain" YJR091C JSN1 0.7 25 1.1 0.3025 0.185161222 iYJR091C 0.290859394 0.490901836 0.226635514 JSN1 -- mitosis (putative) -- when overexpressed can suppress the hyperstable microtubule phenotype of tub2-150 YKL038W RGT1 0.7 21 1.1 0.3025 0.369897572 iYKL039W SNR69 0.396154798 0.488191246 0.64668616 0.486248781 0.346049481 RGT1 -- (glucose) transport -- Negative transcription factor involved in regulation of glucose transporters YML015C TAF40 0.7 22 1.1 0.3025 0.330195828 iYML015C 0.403653055 0.32063197 0.159437947 TAF40 -- transcription -- Component of TAF(II) complex (TBP-associated protein) YNL091W YNL091W 0.7 22 1.1 0.3025 0.134150509 iYNL092W 0.239627573 0.225389864 0.182463499 YNL091W -- unknown -- similarity to Uso1p and human NF2 neurofibromatosis type 2 gene product YOL071W YOL071W 0.7 24 1.1 0.3025 0.132280841 iYOL072W 0.246879587 0.04182911 0.1482355 YOL071W -- unknown -- unknown function YOR141C ARP8 0.7 23 1.1 0.3025 0.094588016 iYOR141C 0.209208835 0.497047087 0.245899909 ARP8 -- cytoskeleton (putative) -- similarity to actin and actin-related proteins Arp1p-Arp10p YOR256C YOR256C 0.7 24 1.1 0.3025 0.181840558 iYOR256C 0.250858092 0.36823425 0.178887546 YOR256C -- unknown -- similarity to secretory protein Ssp134p YPL006W NCR1 0.7 20 1.1 0.3025 0.827551843 iYPL007C 0.176434339 0.338881379 0.245457722 NCR1 -- sterol metabolism (putative) -- sterol homeostatis and trafficking YPL051W ARL3 0.7 22 1.1 0.3025 0.062202936 iYPL052W 0.450529215 0.055311891 0.355171209 "ARL3 -- unknown -- ADP-ribosylation factor-like protein, member of arf-sar family in the ras superfamily" YDL043C PRP11 0.6 17 1.1 0.3025 0.396246264 iYDL043C 0.698935134 0.438853948 0.834643606 "PRP11 -- mRNA splicing -- Pre-mRNA splicing factor, U2, U4, U5, and U6 snRNP-associated protein, has a single C2H2-type zinc finger" YDR231C COX20 0.6 17 1.1 0.3025 0.528032018 iYDR231C 0.558968779 0.849336468 0.814284539 COX20 -- respiration -- maturation of Cox2p and its assembly into cytochrome-c oxidase YDR316W YDR316W 0.6 18 1.1 0.3025 0.19280685 iYDR315C 0.162535118 0.192223925 0.230327215 "YDR316W -- unknown -- unknown function, has predicted S-adenosylmethionine-dependent methyltransferase motid" YDR405W MRP20 0.6 19 1.1 0.3025 0.547399518 iYDR404C 0.286281723 0.682127883 0.306606437 "MRP20 -- protein synthesis -- Mitochondrial ribosomal large subunit (YmL41E. coli L23), belongs to the L23 family of prokaryotic ribosomal proteins" YDR414C ERD1 0.6 18 1.1 0.3025 0.373548754 iYDR414C 0.567737833 0.845810056 0.608665269 ERD1 -- secretion -- retention of lumenal ER proteins YDR460W TFB3 0.6 19 1.1 0.3025 0.298387193 iYDR459C 0.545021341 0.353471668 0.621843995 "TFB3 -- transcription -- Component of RNA polymerase II transcription initiation TFIIH (factor b), 38 kDa subunit" YDR474C YDR474C 0.6 18 1.1 0.3025 0.374179042 iYDR474C 0.221482041 0.793506284 0.190775681 "YDR474C -- unknown -- unknown function, may be a pseudogene or may be separated from YDR475C by sequencing errors" YGL038C OCH1 0.6 17 1.1 0.3025 0.485359313 iYGL038C 0.429218327 0.53768681 0.252694808 "OCH1 -- protein glycosylation -- Alpha-1,6-mannosyltransferase, involved in initiation of mannose outer chain elongation of N-linked oligosaccharides of type Man[9]GlcNac[2]" YHL035C YHL035C 0.6 20 1.1 0.3025 0.577909973 iYHL035C 0.454784244 0.521013148 0.400048755 YHL035C -- unknown -- Member of ATP-binding cassette (ABC) superfamily YIR002C MPH1 0.6 18 1.1 0.3025 0.610866631 iYIR002C 0.387719217 0.90211086 0.629668468 MPH1 -- unknown; mutator null phenotype -- possible role in DNA synthesis or repairhas similarity to ATP-dependent RNA helicases YJL207C YJL207C 0.6 20 1.1 0.3025 0.76202657 iYJL207C 0.485915493 0.513647247 YJL207C -- unknown -- unknown function YKR061W KTR2 0.6 21 1.1 0.3025 0.639235419 iYKR060W 0.673446419 0.922010957 0.770625201 "KTR2 -- protein glycosylation -- Mannosyltransferase of KRE2 family, involved in N-linked glycosylation" YKR096W YKR096W 0.6 20 1.1 0.3025 0.336749072 iYKR095W 0.237342122 0.330363382 0.160207356 YKR096W -- unknown -- strong similarity to Yil151p YLR001C YLR001C 0.6 18 1.1 0.3025 0.680038588 iYLR001C 0.574816436 0.914075701 0.480766161 YLR001C -- unknown -- unknown function YLR144C ACF2 0.6 20 1.1 0.3025 0.204705617 iYLR144C 0.415404529 0.505113472 0.207782791 "ACF2 -- cytoskeleton -- cortical actin assembly, has similarity to C. albicans Eng2p, endo-1,3-beta-glucanase" YLR210W CLB4 0.6 20 1.1 0.3025 0.376719803 iYLR209C 0.245839084 0.777653631 0.340225627 CLB4 -- cell cycle -- G2/M-phase-specific cyclin YLR277C YSH1 0.6 18 1.1 0.3025 0.724109768 iYLR277C 0.691281733 0.823992853 0.87197873 "YSH1 -- mRNA 3'-end processing -- Component of pre-mRNA cleavage factor II (CFII), required for processing of mRNA 3' end" YLR323C YLR323C 0.6 19 1.1 0.3025 0.28560185 iYLR323C 0.629225118 0.667153996 0.427952634 YLR323C -- unknown -- unknown function YML032C RAD52 0.6 19 1.1 0.3025 0.159980706 0.241592682 "RAD52 -- DNA repair and recombination -- recombination and repair of X-ray damage, has a late function in meiotic recombination" YMR278W YMR278W 0.6 18 1.1 0.3025 0.38638681 iYMR277W 0.336493857 0.594263616 0.209515644 YMR278W -- unknown -- simiarity to phosphomannomutase YNL027W CRZ1 0.6 20 1.1 0.3025 0.297778504 iYNL028W 0.319340106 0.361216445 0.705815465 "CRZ1 -- (calcineurin) signaling -- Calcineurin-dependent transcription factor, regulates gene expression downstream of calcineurin in response to multiple environmental signals, has two C2H2-type zinc finger domains" YNL103W MET4 0.6 20 1.1 0.3025 0.418193714 iYNL104C 0.259169329 0.080712788 0.452465356 MET4 -- sulfur amino acid metbolism -- Transcriptional activator of sulfur assimilation pathwaymember of basic leucine zipper (bZIP) family YNL172W APC1 0.6 17 1.1 0.3025 0.386874032 iYNL173C 0.524065487 0.412922481 0.662902315 APC1 -- mitosis -- Component of anaphase-promoting complex (APC)required for Clb2p degradation and for the metaphase-anaphase transition YNL213C YNL213C 0.6 18 1.1 0.3025 0.563868017 iYNL213C 0.441676831 0.343412455 0.591221069 "YNL213C -- unknown -- Putative mitochondrial protein, required for respiration and mitochondrial maintenance" YNL265C IST1 0.6 20 1.1 0.3025 0.335165739 iYNL265C 0.522483635 0.697448462 0.684096036 "IST1 -- salt tolerance (putative) -- similarity to Nuf1p, has a role in resistance to high concentrations of sodium" YOL008W YOL008W 0.6 18 1.1 0.3025 0.534708127 iYOL009C 0.575350945 0.855840858 0.315323224 YOL008W -- unknown -- unknown function YOL009C MDM12 0.6 19 1.1 0.3025 0.247014256 iYOL009C 0.575350945 0.493305995 0.315323224 MDM12 -- mitochondrial inheritance -- Mitochondrial inheritance protein which may function in a complex with Mdm10p at the mitochondrial surface YOL089C HAL9 0.6 20 1.1 0.3025 0.33387138 iYOL089C 0.277429221 0.714473792 0.392272324 "HAL9 -- salt tolerance -- salt tolerance, with similarity to transcription factors, has Zn[2]-Cys[6] fungal-type binuclear cluster domain in the N-terminal region" YOR069W VPS5 0.6 17 1.1 0.3025 0.35331591 iYOR068C 0.291961717 0.573264166 0.276137271 VPS5 -- vacuolar protein targeting -- Member of sorting nexin family involved in Golgi retention and vacuolar sorting YOR112W YOR112W 0.6 18 1.1 0.3025 0.348632022 iYOR111W 0.693830307 0.188759977 0.56916996 YOR112W -- unknown -- unknown function YOR205C YOR205C 0.6 20 1.1 0.3025 0.290576436 iYOR205C 0.276502633 0.567173305 0.197228489 YOR205C -- unknown -- unknown function YOR278W HEM4 0.6 18 1.1 0.3025 0.614183987 iYOR277C 0.796308348 0.705985634 0.796629299 "HEM4 -- heme biosynthesis -- Uroporphyrinogen III synthase, fourth step in heme biosynthesis pathway" YPL052W YPL052W 0.6 20 1.1 0.3025 0.435497529 iYPL053C 0.378822831 0.431923384 0.4562704 YPL052W -- unknown -- unknown function YPL088W YPL088W 0.6 18 1.1 0.3025 0.31908578 iYPL089C 0.415662771 0.235993615 0.17450854 "YPL088W -- unknown -- Putative aryl alcohol dehydrogenase, may participate in late steps of degradation of aromatic compounds that arise from the degradation of lignocellulose" YPR160W GPH1 0.6 17 1.1 0.3025 0.620350749 iYPR159W tG(GCC)P2 0.635482579 0.723153058 0.57681231 0.700567761 0.375524109 "GPH1 -- glycogen metabolism -- Glycogen phosphorylase, releases alpha-D-glucose-1-phosphate from glycogen" YPR180W AOS1 0.6 19 1.1 0.3025 0.363758027 iYPR179C 0.513546105 0.641263941 0.557536645 "AOS1 -- protein degradation, Smt3p-mediated -- Subunit of a heterodimeric enzyme consisting of Uba2p and Aos1p, activates the ubiquitin-like Smt3p for conjugation to other proteins" YPR198W SGE1 0.6 20 1.1 0.3025 0.053711457 0.151072125 "SGE1 -- crystal violet resistance -- Crystal violet resistance protein, member of multidrug-resistance 14-spanner family of major facilitator superfamily (MFS-MDR)" YBR119W MUD1 0.4 14 1.1 0.3025 0.524723241 iYBR118W 0.828128917 0.581027668 0.485623782 MUD1 -- mRNA splicing -- U1 snRNP A protein (snRNA-associated protein) with 2 RNA recognition (RRM) domains YBR260C RGD1 0.4 14 1.1 0.3025 0.358573053 iYBR260C 0.262849773 0.687628813 0.420281079 RGD1 -- unknown -- GTPase-activating protein (GAP) for Rho3p and Rho4p YBR281C YBR281C 0.4 17 1.1 0.3025 0.119648943 iYBR281C 0.520424245 0.421044151 0.814929358 "YBR281C -- unknown -- unknown function, has WD (WD-40) repeats" YDR052C DBF4 0.4 18 1.1 0.3025 0.577678289 0.410030218 "DBF4 -- cell cycle -- Regulatory subunit for Cdc7p protein kinase, required for G1/S transition" YDR222W YDR222W 0.4 15 1.1 0.3025 0.690437545 iYDR221W 0.42771572 0.927631579 0.617230314 YDR222W -- unknown -- unknown function YDR246W TRS23 0.4 15 1.1 0.3025 0.088109921 iYDR245W 0.640937454 0.057063049 0.452891488 TRS23 -- secretion (putative) -- TRAPP (Transport Protein Particle) complex involved in vesicular transport from endoplasmic reticulum to Golgi YDR270W CCC2 0.4 16 1.1 0.3025 0.638115561 0.696825653 CCC2 -- oxidative phosphorylation -- Copper-transporting P-type ATPasemember of cation transport (E1-E2) ATPase family YDR320C YDR320C 0.4 13 1.1 0.3025 0.346782032 iYDR320C 0.29164636 0.637867193 0.539793849 YDR320C -- unknown -- weak similarity to human transformation-sensitive protein IEF and to mouse HSP90-binding immunophilin protein YDR334W SWR1 0.4 14 1.1 0.3025 0.292136568 iYDR333C 0.494748389 0.299679092 0.44820431 "SWR1 -- RNA processing (putative) -- similarity to Snf2p, member of Snf2p DNA helicase ATPase family" YDR362C TFC6 0.4 14 1.1 0.3025 0.188671736 iYDR362C 0.473671517 0.710797567 0.424296201 "TFC6 -- transcription -- RNA polymerase III transcription initiation factor TFIIIC (tau), 91-kDa subunit" YDR470C YDR470C 0.4 13 1.1 0.3025 0.954018295 iYDR470C 0.990595751 0.580679668 0.435859459 "YDR470C -- unknown -- unknown function, predicted to be a member of mitochondrial carrier family (MCF)of proteins" YER014W HEM14 0.4 15 1.1 0.3025 0.405177265 iYER013W 0.344413561 0.573356373 0.352078634 "HEM14 -- heme biosynthesis -- Protoporphyrinogen oxidase, converts protoporphyrinogen to protoporphyrin, the last step in heme biosynthesis" YER028C YER028C 0.4 14 1.1 0.3025 0.35365443 iYER028C 0.517873414 0.735468064 0.618617407 "YER028C -- unknown -- similarity to Mig2p, Tup1p-dependent and glucose-dependent transcriptional repressor with unknown function" YER061C CEM1 0.4 16 1.1 0.3025 0.737197524 iYER061C 0.475839227 0.954990537 0.508211041 "CEM1 -- fatty acid metabolism -- Beta-ketoacyl-ACP synthase, mitochondrial (3-oxoacyl-[Acyl-carrier-protein] synthase)" YER068W SIG1 0.4 15 1.1 0.3025 0.504621165 iYER067W 0.491197632 0.292700612 0.75042349 SIG1 -- mating -- Zinc finger transcriptional repressorinvolved in G-protein mediated pheromone signal transduction YGR011W YGR011W 0.4 14 1.1 0.3025 0.75322838 0.835594573 YGR011W -- unknown -- unknown function YGR113W DAM1 0.4 16 1.1 0.3025 0.541002938 iYGR112W 0.577753577 0.780051982 0.733519553 "DAM1 -- unknown -- Duo1p-interacting protein, required for maintenance of spindle integrity during mitosis" YHL032C GUT1 0.4 14 1.1 0.3025 0.931224483 iYHL032C 0.179761516 0.872059297 0.061053472 "GUT1 -- glycerol utilization -- Glycerol kinase, catalyzes conversion of glycerol to glycerol-3-phosphate" YJL176C SWI3 0.4 16 1.1 0.3025 0.282399462 0.174186271 SWI3 -- transcription -- Component of SWI-SNF global transcription activator complexacts to assist gene-specific activators through chromatin remodeling YJL181W YJL181W 0.4 14 1.1 0.3025 0.782435806 0.948830409 YJL181W -- unknown -- unknown function YJL188C YJL188C 0.4 15 1.1 0.3025 0.876383984 iYJL188C 0.693138993 0.292812014 0.52014295 YJL188C -- unknown -- unknown functionquestionable ORF YKL121W YKL121W 0.4 17 1.1 0.3025 0.234959812 iYKL122C 0.338214021 0.567761047 0.468305814 "YKL121W -- unknown -- unknown function, member of WD (WD-40) repeat family" YLR033W YLR033W 0.4 16 1.1 0.3025 0.246341732 iYLR032W 0.313149296 0.363922011 0.130091335 YLR033W -- unknown -- similarity to human TFIIIC90 YLR046C YLR046C 0.4 13 1.1 0.3025 0.633757744 iYLR046C 0.587697066 0.462208599 0.639703513 YLR046C -- unknown -- similarity to Rtm1p YLR076C YLR076C 0.4 14 1.1 0.3025 0.938297585 iYLR076C 0.856084917 YLR076C -- unknown -- unknown function YLR132C YLR132C 0.4 14 1.1 0.3025 0.385670091 iYLR132C 0.564014958 0.707561919 0.611376807 YLR132C -- unknown -- unknown function YLR361C YLR361C 0.4 13 1.1 0.3025 0.425481622 iYLR361C 0.161275988 0.849178215 0.52612566 YLR361C -- unknown -- unknown function YLR383W RHC18 0.4 15 1.1 0.3025 0.328891764 iYLR382C 0.235596557 0.465920077 0.305905826 "RHC18 -- DNA repair, recombination -- recombination repair, homologous to S. pombe rad18" YML054C CYB2 0.4 16 1.1 0.3025 0.369758783 iYML054C iYMLCdelta2 0.101455101 0.543062976 0.577079272 0.132873232 0.407788918 CYB2 -- lactate utilization -- Cytochrome b2 [L-(+)-lactate cytochrome-c oxidoreductase]converts L-lactate to pyruvate YMR098C YMR098C 0.4 14 1.1 0.3025 0.464223596 iYMR098C iYMRCdelta13 0.258748072 0.55928707 0.756274171 0.445858846 0.273618478 YMR098C -- unknown -- unknown function YMR187C YMR187C 0.4 14 1.1 0.3025 0.632605824 iYMR187C 0.488424295 0.869645882 0.266847692 YMR187C -- unknown -- unknown function YMR313C YMR313C 0.4 14 1.1 0.3025 0.423621383 iYMR313C 0.487248705 0.445027023 0.489508763 YMR313C -- unknown -- unknown function YNL317W PFS2 0.4 14 1.1 0.3025 0.647283455 iYNL318C 0.112218229 0.547292942 0.096491228 "PFS2 -- mRNA processing -- Polyadenylation factor I subunit 2 required for mRNA 3'-end processing, bridges two mRNA 3'-end processing factors, has WD (WD-40) repeats" YOL028C YAP7 0.4 15 1.1 0.3025 0.368677438 iYOL028C 0.313459654 0.220605184 0.338531514 "YAP7 -- transcription -- Transcription factor of basic leucine zipper (bZIP) family, member of a fungal-specific family of bZIP proteins" YOL145C CTR9 0.4 16 1.1 0.3025 0.420214386 iYOL145C 0.484705145 0.385352884 0.227113906 "CTR9 -- mitosis, chromosome segregation -- normal expression of G1 cyclins CLN1 and CLN2, has tetratricopeptide (TPR) repeats" YOR304C-A YOR304C-A 0.4 14 1.1 0.3025 0.337775868 iYOR304C-A 0.218545113 0.322820037 0.07750564 YOR304C-A -- unknown -- unknown function YPL056C YPL056C 0.4 14 1.1 0.3025 0.153047768 iYPL056C 0.486996342 0.020670391 0.126635399 YPL056C -- unknown -- unknown function YPL137C YPL137C 0.4 15 1.1 0.3025 0.336875323 0.646850044 YPL137C -- unknown -- similarity to Mhp1p YPL141C YPL141C 0.4 17 1.1 0.3025 0.320078579 iYPL141C 0.205358588 0.343866171 0.431649206 YPL141C -- unknown -- Serine/threonine protein kinase with similarity to Kin4p YPL228W CET1 0.4 17 1.1 0.3025 0.629792739 iYPL229W 0.473696392 0.420510774 0.401397011 "CET1 -- mRNA capping -- mRNA capping enzyme beta subunit, RNA 5'-triphosphatase" YPR070W MED1 0.4 15 1.1 0.3025 0.710144488 iYPR069C 0.767032144 0.534887473 0.799266247 MED1 -- transcription -- Component of RNA polymerase II holoenzyme and mediator subcomplex YPR105C YPR105C 0.4 15 1.1 0.3025 0.835738601 iYPR105C 0.93163198 0.650157296 0.500760392 YPR105C -- unknown -- unknown function YPR135W CTF4 0.4 15 1.1 0.3025 0.682660198 iYPR134W 0.18275738 0.352587838 0.090613582 "CTF4 -- DNA replication -- DNA synthesis, binds DNA polymerase alpha" YAL001C TFC3 0.3 11 1.1 0.3025 0.532649786 iYAL001C CEN1 0.283867159 0.793589121 0.296214937 0.552472372 0.597331661 "TFC3 -- transcription -- RNA polymerase III transcription initiation factor TFIIIC (tau), 138 kDa subunit" YAL010C MDM10 0.3 12 1.1 0.3025 0.48070366 iYAL010C 0.365233864 0.768236233 0.510715437 MDM10 -- mitochondrial biogenesis -- coupling mitochondria to the actin cytoskeleton and in mitochondrial morphology and inheritance YAR028W YAR028W 0.3 12 1.1 0.3025 0.836332451 iYAR027W 0.483269039 0.916747888 0.751068807 "YAR028W -- unknown -- strong similarity to subtelomerically-encoded proteins such as Cos5p, Ybr302p, Cos3p, Cos1p, Cos4p, Cos8p, Cos6p, Cos9p, and Ycr007p" YDL138W RGT2 0.3 14 1.1 0.3025 0.481121682 iYDL139C 0.48320887 0.310272537 0.588028731 "RGT2 -- transport -- Glucose transporter responsible for induction of gene expression in the presence of high glucose, member of hexose transporter family of major facilitator superfamily (MFS)" YDR213W YDR213W 0.3 12 1.1 0.3025 0.307360677 iYDR212W 0.170283421 0.595326257 0.288225582 "YDR213W -- unknown -- uptake and intracellular esterification of intracellular cholesterol, has Zn[2]-Cys[6] fungal-type binuclear cluster domain in the N-terminal region" YDR415C YDR415C 0.3 13 1.1 0.3025 0.689150943 iYDR415C 0.328634104 0.876616121 0.17382949 YDR415C -- unknown -- similarity to bacterial leucyl aminopeptidase YEL068C YEL068C 0.3 10 1.1 0.3025 0.827016129 iYEL068C 0.551202822 0.933761211 0.42557652 YEL068C -- unknown -- unknown function YER128W YER128W 0.3 11 1.1 0.3025 0.312365763 iYER127W 0.40835643 0.727176738 0.300831071 YER128W -- unknown -- unknown function YFR013W IOC3 0.3 12 1.1 0.3025 0.353717266 iYFR012W 0.162337037 0.809676623 0.138807667 IOC3 -- unknown -- unknown function YGR041W BUD9 0.3 12 1.1 0.3025 0.350825797 iYGR040W 0.395253706 0.565662262 0.350795971 "BUD9 -- bud site selection, bipolar -- bipolar buddingmutant diploid strains bud only at distal pole" YIL131C FKH1 0.3 12 1.1 0.3025 0.788228268 iYIL131C 0.195731739 0.651153346 0.171849823 "FKH1 -- unknown -- Homolog of Drosophila forkhead protein, involved in transcriptional silencing, cell morphology and cell cycle" YLR010C YLR010C 0.3 12 1.1 0.3025 0.696844769 iYLR010C iYLRCsigma1 0.354397641 0.19087414 0.779827526 0.353770545 0.556341719 YLR010C -- unknown -- unknown function YLR456W YLR456W 0.3 12 1.1 0.3025 0.696561421 iYLR455W 0.513910704 0.857146829 0.429140845 YLR456W -- unknown -- unknown function YMR016C SOK2 0.3 10 1.1 0.3025 0.835581898 iYMR016C-0 iYMR016C-1 0.212346786 0.281134473 0.254258208 0.357154367 0.435941743 SOK2 -- unknown -- can suppress mutants of cAMP-dependent protein kinase when overexpressed YNL173C MDG1 0.3 12 1.1 0.3025 0.371950791 iYNL173C 0.524065487 0.245536082 0.662902315 "MDG1 -- signaling, pheromone pathway -- signal transduction in the mating response" YNL234W YNL234W 0.3 12 1.1 0.3025 0.761129998 iYNL235C 0.310167388 0.231167661 YNL234W -- unknown -- Hemo similarity to mammalian globins YOL053W YOL053W 0.3 13 1.1 0.3025 0.401590395 iYOL054W 0.125528186 0.53782921 0.070823586 YOL053W -- unknown -- unknown function YOL055C THI20 0.3 13 1.1 0.3025 0.442515025 iYOL055C YOLWdelta6 0.540391776 0.723782812 0.87669593 0.294324023 0.532707973 "THI20 -- thiamine metabolism (putative) -- Bipartite protein consisting of N-terminal hydroxymethylpyrimidine phosphate (HMP-P) kinase domain, needed for thiamine biosynthesis, fused to C-terminal Pet18p-like domain of indeterminant function" YOR022C YOR022C 0.3 13 1.1 0.3025 0.286469079 iYOR022C 0.320269313 0.432645604 0.089111491 YOR022C -- unknown -- unknown function YOR172W YOR172W 0.3 13 1.1 0.3025 0.535828657 iYOR171C 0.250350689 0.331687649 0.280838121 "YOR172W -- unknown -- similarity to transcription factors, has Zn[2]-Cys[6] fungal-type binuclear cluster domain in the N-terminal region" YPL255W BBP1 0.3 10 1.1 0.3025 0.230732786 iYPL256C 0.130227367 0.338228252 0.154776598 BBP1 -- cell cycle and meiosis -- spindle pole body that binds to Bfr1p YPR011C YPR011C 0.3 11 1.1 0.3025 0.21880328 iYPR011C 0.200434461 0.238541924 0.180118798 "YPR011C -- unknown -- similarity to human Grave's disease carrier protein and to bovine homolog of Grave's disease protein, member of mitochondrial carrier family (MCF) of membrane transporters" YHL014C YLF2 0.2 10 1.1 0.3025 0.644315002 iYHL014C 0.348706311 0.90497076 0.532950321 YLF2 -- unknown -- similarity to E. coli gtp1 gene product YMR048W YMR048W 0.2 9 1.1 0.3025 0.075748824 iYMR047C 0.168601696 0.26859974 0.105750487 YMR048W -- unknown -- unknown function YPL029W SUV3 0.2 10 1.1 0.3025 0.120862882 iYPL030W 0.221978309 0.101675798 0.274923961 "SUV3 -- RNA processing, mitochondrial -- Mitochondrial RNA helicase of DEAD box family, component of mitochondrial NTP-dependent 3'-5' exonuclease responsible for degradation of group I intron RNA" YLR310C CDC25 1.3 48 1 0.2723 1 0.482452555 iYLR310C 0.98865422 0.218754988 0.325785738 "CDC25 -- signaling -- Guanine-nucleotide exchange protein for Ras1p and Ras2p, has an SH3 domain" YGL071W RCS1 0.8 30 1 0.2723 1 0.871784843 iYGL072C 0.975433755 0.609327475 0.400096681 RCS1 -- iron transport -- Transcription factor that regulates genes involved in iron uptake and control of cell size YGL073W HSF1 0.6 20 1 0.2723 1 0.977167142 0.589587394 HSF1 -- heat shock -- Heat shock transcription factor that binds to the heat shock DNA element at both normal and elevated temperatures YDR393W SHE9 0.3 13 1 0.2723 1 0.635145034 iYDR392W 0.98510363 0.957023061 0.204109812 "SHE9 -- unknown -- similarity to Arabidopsis thaliana CIP1, causes lethality when overexpressed" YOR374W ALD4 1.5 55 1 0.2723 0.853868742 iYOR373W 0.375700695 0.768794892 0.276228092 ALD4 -- ethanol utilization -- Mitochondrial aldehyde dehydrogenase YKL141W SDH3 1.3 52 1 0.2723 0.381001195 iYKL142W 0.125101557 0.537124389 0.391380686 "SDH3 -- TCA cycle, oxidative phosphorylation -- Membrane anchor subunit for Sdh1p in the succinate dehydrogenase complex" YBR290W BSD2 1.2 44 1 0.2723 0.216514211 iYBR289W 0.278586778 0.381866581 0.054932645 BSD2 -- transport -- Metal homeostasis protein YLR258W GSY2 1.2 42 1 0.2723 0.582626728 iYLR257W 0.476143971 0.836500975 0.768518519 GSY2 -- glycogen metabolism -- UDP-glucose-starch glucosyltransferase (glycogen synthetase) isoform 2 YER053C YER053C 1.1 41 1 0.2723 0.483699113 iYER053C-0 iYER053C-1 0.191079606 0.54556538 0.576565457 0.360973663 0.421788859 "YER053C -- unknown -- Member of mitochondrial carrier (MCF) family of membrane transporters, has similarity to C. elegans mitochondrial phosphate carrier protein" YGR149W YGR149W 1.1 41 1 0.2723 0.955544538 iYGR148C 0.97676142 0.86244398 0.385214623 YGR149W -- unknown -- similarity to hypothetical protein A-288 YCR088W ABP1 1 39 1 0.2723 0.232092612 iYCR087C-A 0.419467411 0.466645182 0.554917202 "ABP1 -- cytoskeleton -- Actin binding protein, may help to stabilize actin filaments at the bud site, has an SH3 domain" YOR079C ATX2 0.9 33 1 0.2723 0.230981061 iYOR079C 0.536180201 0.61245012 0.507258803 ATX2 -- oxidative stress response -- Manganese-trafficking protein YDL110C YDL110C 0.8 27 1 0.2723 0.403747343 iYDL110C 0.296310034 0.23782921 0.745650439 YDL110C -- unknown -- unknown function YFL036W RPO41 0.8 30 1 0.2723 0.661875295 iYFL037W 0.341663872 0.862386061 0.281849926 "RPO41 -- transcription -- RNA polymerase, mitochondrial" YML117W YML117W 0.8 26 1 0.2723 0.325979177 iYML118W 0.332341828 0.436718561 0.286359603 YML117W -- unknown -- unknown function YMR110C YMR110C 0.8 27 1 0.2723 0.415632146 iYMR110C 0.656799778 YMR110C -- unknown -- similarity to aldehyde dehydrogenases YBR130C SHE3 0.7 26 1 0.2723 0.446466589 iYBR130C 0.308375426 0.727288609 0.419057691 SHE3 -- cell polarity -- mother cell-specific expression of HO YBR301W YBR301W 0.7 27 1 0.2723 0.919534779 0.426895451 YBR301W -- unknown -- Member of seripauperin (PAU) family YCR065W HCM1 0.7 23 1 0.2723 0.490775993 iYCR063W 0.542521199 0.603750998 0.634144376 HCM1 -- transcription (putative) -- Dosage-dependent suppressor of cmd1 and member of forkhead family of DNA-binding proteins YCR071C IMG2 0.7 27 1 0.2723 0.746303541 iYCR071C 0.621465312 0.63176575 0.517867226 IMG2 -- mitochondrial DNA maintenance -- mitochondrial genome integrity YDL009C YDL009C 0.7 24 1 0.2723 0.463796187 iYDL009C 0.616924038 0.654110136 0.635913807 YDL009C -- unknown -- unknown function YGL086W MAD1 0.7 28 1 0.2723 0.64436343 iYGL087C 0.474160086 0.455204641 0.267241379 MAD1 -- cell cycle -- Coiled-coil spindle-assembly checkpointrequired for cell cycle delay in response to impaired kinetochore function YGR111W YGR111W 0.7 24 1 0.2723 0.522541468 iYGR110W 0.4191765 0.880364988 0.649122807 YGR111W -- unknown -- similarity to southern house mosquito carboxylesterase PIR YKR095W MLP1 0.7 23 1 0.2723 0.519720021 iYKR094C 0.988725428 0.227638015 0.5581189 "MLP1 -- DNA repair (putative) -- Myosin-like protein, has a probable coiled-coil structure" YLL015W BPT1 0.7 24 1 0.2723 0.513948067 iYLL016W 0.206947768 0.740170802 0.217348928 "BPT1 -- transport -- Membrane transporter of ATP-binding cassette (ABC) superfamily, capable of transporting unconjugated bilirubin into the vacuole" YML025C YML025C 0.7 24 1 0.2723 0.985876487 iYML025C 0.991089628 0.529158545 0.056465274 "YML025C -- protein synthesis -- Mitochondrial ribosomal large subunit, member of L4 family of ribosomal proteins" YML033W 0.7 27 1 0.2723 0.501288492 iYML034W 0.25088685 0.548043326 0.091457023 YOR033C DHS1 0.7 24 1 0.2723 0.306459446 iYOR033C 0.467197948 0.158018868 "DHS1 -- DNA repair -- Double-stranded DNA 5'->3' exonuclease, involved in mismatch repair and recombination" YPL075W GCR1 0.7 25 1 0.2723 0.504402188 iYPL076W-0 iYPL076W-1 0.764864423 0.831738886 0.569815278 0.428459119 0.282282522 "GCR1 -- glycolysis -- expression of glycolytic genescauses same spectrum of enzymatic changes as does Gcr2p, activator of glycolytic genes" YPL259C APM1 0.7 24 1 0.2723 0.200831989 iYPL259C 0.103874882 0.373781676 0.112647083 APM1 -- secretion -- Medium subunit of clathrin-associated protein (AP) complex YPR174C YPR174C 0.7 26 1 0.2723 0.128466919 iYPR174C 0.422414977 0.363974316 0.448039878 YPR174C -- unknown -- weak similarity to C. elegans nuclear lamin YBL046W YBL046W 0.6 22 1 0.2723 0.099568272 iYBL047C 0.763733693 0.125401136 0.850628424 YBL046W -- unknown -- unknown function YBR258C YBR258C 0.6 20 1 0.2723 0.055816746 iYBR258C 0.538111332 0.161053472 0.648646471 YBR258C -- unknown -- unknown function YCR052W RSC6 0.6 21 1 0.2723 0.127693101 iYCR051W 0.741173917 0.246507472 0.70049003 RSC6 -- chromatin structure -- Component of abundant RSC complex involved in chromatin remodeling YDR117C YDR117C 0.6 19 1 0.2723 0.180637018 iYDR117C 0.517986659 0.707751875 0.360651771 "YDR117C -- unknown -- unknown function, synthesized during sporulation" YDR265W PEX10 0.6 21 1 0.2723 0.854543415 iYDR264C 0.806919898 0.84405427 0.655494683 PEX10 -- peroxisome biogenesis -- Peroxisomal biogenesis protein YDR319C YDR319C 0.6 18 1 0.2723 0.726015789 iYDR319C 0.272442614 0.923138898 0.636871508 YDR319C -- unknown -- unknown function YDR462W MRPL28 0.6 20 1 0.2723 0.39215371 iYDR461W 0.195208065 0.590901836 0.242800678 MRPL28 -- protein synthesis -- Mitochondrial ribosomal large subunit YDR469W YDR469W 0.6 21 1 0.2723 0.659507235 iYDR468C 0.508739339 0.66705597 0.345922677 "YDR469W -- unknown -- similarity to C. elegans dpy-30 gene product, GB" YER123W YCK3 0.6 21 1 0.2723 0.439903155 iYER122C 0.483179877 0.867138365 0.309429701 "YCK3 -- cell proliferation -- Casein kinase I isoform, plasma membrane-bound" YFL034C-B 0.6 21 1 0.2723 0.576791351 iYFL035C-A YFL034C-A 0.440759153 0.902407492 0.247292103 0.14011181 0.346827944 YFL044C YFL044C 0.6 21 1 0.2723 0.874829166 iYFL044C 0.334979107 0.871823828 0.398584712 "YFL044C -- unknown -- unknown function, has a single C2H2-type zinc finger" YGL006W PMC1 0.6 21 1 0.2723 0.315118692 iYGL007W-0 iYGL007W-1 0.903674923 0.524452185 0.547565842 0.737832692 0.732083001 "PMC1 -- transport -- Vacuolar Ca2+-transporting P-type ATPase, member of cation transporting (E1-E2) P-type ATPase superfamily, functions to pump Ca2+ into the vacuole" YGL211W YGL211W 0.6 23 1 0.2723 0.51346858 iYGL212W 0.221793388 0.949741324 0.152078405 YGL211W -- unknown -- unknown function YGL219C YGL219C 0.6 23 1 0.2723 0.315972418 0.592679944 YGL219C -- unknown -- similarity to Mycoplasma genitalium threoninyl-tRNA synthetase YGR194C XKS1 0.6 20 1 0.2723 0.705178518 iYGR194C 0.432163898 0.881091618 0.501520784 "XKS1 -- xylulose utilization -- Xylulokinase, required for growth on D-xylulose" YGR268C YGR268C 0.6 19 1 0.2723 0.197124642 0.526656026 YGR268C -- unknown -- unknown function YGR274C TAF145 0.6 20 1 0.2723 0.178269556 iYGR274C 0.54591963 0.292419074 0.398868137 TAF145 -- transcription -- Component of TAF(II) complex (TBP-associated protein complex)required for activated transcription by RNA polymerase II YHL030W ECM29 0.6 19 1 0.2723 0.604409216 iYHL031C 0.427004482 0.623860611 0.247675471 ECM29 -- cell wall biogenesis -- Protein possibly involved in cell wall structure or biosynthesis YHR038W FIL1 0.6 19 1 0.2723 0.596764668 iYHR037W 0.412332181 0.535371461 0.168274994 "FIL1 -- protein syntehsis -- Mitochondrial ribosome recycling factor, involved in sensitivity to mutagens diepoxybutane and/or mitomycin C" YHR102W KIC1 0.6 21 1 0.2723 0.19743746 iYHR101C 0.123080693 0.363071711 0.396199252 KIC1 -- mitosis (putative) -- Serine/threonine protein kinase that interacts with Cdc31p YIL165C YIL165C 0.6 21 1 0.2723 0.362024691 0.805726981 "YIL165C -- unknown -- P similarity to nitrilases, may be a pseudogene or separated from NIT1 by sequencing errors" YJR092W BUD4 0.6 23 1 0.2723 0.335058065 iYJR091C 0.290859394 0.275091822 0.226635514 "BUD4 -- bud site selection, axial -- axial budding but not for bipolar budding" YJR096W YJR096W 0.6 23 1 0.2723 0.684580203 iYJR095W 0.386473777 0.968954509 0.775942636 YJR096W -- unknown -- similarity to aldolase reductase YKL022C CDC16 0.6 22 1 0.2723 0.791703513 iYKL022C 0.590497005 0.916423002 0.353154567 "CDC16 -- cell cycle -- Component of anaphase-promoting complex (APC), required for Clb2p degradation and for the metaphase-anaphase transition" YKL148C SDH1 0.6 22 1 0.2723 0.421833009 iYKL148C 0.266911578 0.742313068 0.065662799 "SDH1 -- TCA cycle, oxidative phosphorylation -- Succinate dehydrogenase (ubiquinone) flavoprotein (Fp) subunit, converts succinate plus ubiquinone to fumarate plus ubiquinol in the TCA cycle" YLR071C RGR1 0.6 19 1 0.2723 0.433007011 iYLR071C 0.294838288 0.88137666 0.128740824 RGR1 -- transcription -- Component of RNA polymerase II holoenzyme and Kornberg's mediator (SRB) complexhas positive and negative effects on transcription YLR160C ASP3D 0.6 21 1 0.2723 0.358448102 iYLR160C-0 iYLR160C-1 0.183422373 0.256546143 0.76754386 0.476919279 "ASP3D -- asparagine utilization -- L-asparaginase II, extracellular" YLR299W ECM38 0.6 21 1 0.2723 0.364770242 iYLR298C 0.335212402 0.59591195 0.373981733 ECM38 -- glutathione biosynthesis -- Putative gamma-glutamyltransferase involved in glutathione synthesis YLR442C SIR3 0.6 23 1 0.2723 0.911798617 iYLR442C 0.255065072 0.255198181 0.276478233 "SIR3 -- silencing -- maintenance of silencing of HMR, HML, and telomeres, member of AAA+ family of putative ATPases" YML013W YML013W 0.6 24 1 0.2723 0.482343316 iYML014W 0.07312886 0.623348373 0.099009097 YML013W -- unknown -- unknown function YML049C RSE1 0.6 19 1 0.2723 0.299961092 iYML049C 0.601116415 0.161874594 0.540223464 "RSE1 -- secretion and RNA splicing -- U2 snRNP-associated pre-mRNA splicing, indirectly involved in ER to Golgi transport" YMR275C BUL1 0.6 21 1 0.2723 0.382139 iYMR275C 0.232602647 0.751830824 0.118272639 "BUL1 -- protein degradation, ubiquitin-mediated -- the ubiquitination pathway" YMR299C YMR299C 0.6 19 1 0.2723 0.371442929 iYMR299C 0.60975708 0.931524342 0.419684187 YMR299C -- unknown -- unknown function YNL114C YNL114C 0.6 20 1 0.2723 0.050245871 0.122126321 "YNL114C -- unknown -- unknown function, questionable ORF" YNL251C NRD1 0.6 19 1 0.2723 0.258891614 iYNL251C 0.614831754 0.23622301 0.627355426 "NRD1 -- transcription -- controls transcriptional elongation, interacts with the C-terminal domain of RNA polymerase II large subunit and binds DNA through a RNA recognition (RRM) domain" YNR034W SOL1 0.6 23 1 0.2723 0.19799471 iYNR033W 0.344860442 0.671121593 "SOL1 -- tRNA splicing, putative -- Possible 6-phosphogluconolactonaseinvolved in tRNA synthesis and function" YOL044W PEX15 0.6 19 1 0.2723 0.858107565 iYOL045W 0.535195259 0.942483337 0.220260223 PEX15 -- peroxisome biogenesis -- Peroxisomal integral membrane peroxisome assembly YOR028C CIN5 0.6 22 1 0.2723 0.137747438 iYOR028C 0.442425046 0.146736177 0.197715628 "CIN5 -- salt tolerance -- Transcription factor of basic leucine zipper (bZIP) family and one of eight members of a fungal-specific family of bZIP proteins, involved in salt tolerance" YOR054C YOR054C 0.6 21 1 0.2723 0.218788043 0.404699511 YOR054C -- unknown -- similarity to Sis2p YOR075W UFE1 0.6 19 1 0.2723 0.276690753 iYOR074C 0.159861244 0.28974752 0.270151636 UFE1 -- secretion -- Syntaxin homolog (t-SNARE) of endoplasmic reticulum required for targeting of vesicles to the ER YPL181W YPL181W 0.6 20 1 0.2723 0.549264797 0.301563004 "YPL181W -- unknown -- unknown function, contains a PHD finger" YPL202C YPL202C 0.6 22 1 0.2723 0.421721789 iYPL202C 0.297970188 0.402534113 0.152191428 YPL202C -- unknown -- similarity to Rcs1p YPR185W APG13 0.6 22 1 0.2723 0.043861927 iYPR184W 0.331594318 0.053546471 0.472021934 APG13 -- autophagy -- autophagy YAL011W YAL011W 0.4 16 1 0.2723 0.251973714 iYAL012W 0.567254957 0.355100715 0.432323558 "YAL011W -- unknown -- unknown function, has a predicted mitochondrial transit peptide" YBR204C YBR204C 0.4 17 1 0.2723 0.261355983 iYBR204C 0.509500273 0.606145251 0.800919577 "YBR204C -- unknown -- similarity to serine-active lipases, localized to lipid droplets" YDR020C YDR020C 0.4 19 1 0.2723 0.142556326 iYDR020C 0.433498885 0.298563448 0.419069456 YDR020C -- unknown -- weak similarity to uridine kinases and phosphoribulokinases YDR034C LYS14 0.4 18 1 0.2723 0.419529051 iYDR034C iYDRCdelta3 0.40701067 0.82338707 0.535127296 0.58603352 0.645236751 LYS14 -- lysine biosynthesis -- Transcriptional activator of lysine pathway genes with 2-aminoadipate semialdehyde as coinducer YDR137W RGP1 0.4 16 1 0.2723 0.731219069 0.853963613 RGP1 -- unknown -- proper mitotic growth YDR191W HST4 0.4 16 1 0.2723 0.539567321 iYDR190C 0.589241448 0.873014532 0.440302144 HST4 -- silencing (telomere) -- similarity to Sir2p YDR243C PRP28 0.4 18 1 0.2723 0.172418586 iYDR243C 0.284931027 0.439026337 0.46539961 "PRP28 -- mRNA splicing -- Pre-mRNA splicing factor of DEAD box family, needed for the first covalent step of splicing" YDR282C YDR282C 0.4 16 1 0.2723 0.631910456 iYDR282C 0.244043026 0.922736062 0.691991621 YDR282C -- unknown -- unknown function YDR287W YDR287W 0.4 18 1 0.2723 0.407104676 iYDR286C 0.0209082 0.649592643 0.115291653 YDR287W -- unknown -- similarity to inositol monophosphatase YDR422C SIP1 0.4 17 1 0.2723 iYDR422C 0.59417328 0.460060094 "SIP1 -- transcription -- Multicopy suppressor of snf1, has similarity to Gal83p/Spm1p and Spm2p" YDR489W YDR489W 0.4 15 1 0.2723 0.312082965 iYDR488C 0.33020313 0.63175351 0.23336291 YDR489W -- unknown -- unknown function YEL064C YEL064C 0.4 15 1 0.2723 0.549003594 iYEL064C 0.187961725 0.410972969 0.064327485 YEL064C -- unknown -- Putative membrane transporter of amino acid/auxin permease (AAAP) family YER093C TSC11 0.4 15 1 0.2723 0.638896243 iYER093C 0.34548115 TSC11 -- unknown -- maximal growth on caffeine YFL035C-A 0.4 16 1 0.2723 YGL088W YGL088W 0.4 18 1 0.2723 0.90323082 iYGL089C 0.704456952 0.446675625 0.556264964 YGL088W -- unknown -- unknown function YGL113W YGL113W 0.4 15 1 0.2723 0.601094145 iYGL114W 0.514292715 0.585395052 0.263289506 YGL113W -- unknown -- unknown function YGL121C YGL121C 0.4 15 1 0.2723 0.858193136 iYGL121C 0.551966974 0.938056871 0.815789474 YGL121C -- unknown -- unknown function YGL201C MCM6 0.4 15 1 0.2723 0.223022816 iYGL201C itK(CUU)G1 0.500961132 0.434164467 0.365855624 0.820843753 0.447406225 "MCM6 -- DNA replication -- DNA replication, member of MCM/P1 family of proteins" YGR003W YGR003W 0.4 16 1 0.2723 0.63683776 iYGR002C 0.592459242 0.927240461 0.554677857 "YGR003W -- unknown -- cullin family, with similarity to Cdc53p and Rtt101p" YGR099W TEL2 0.4 16 1 0.2723 0.386475749 iYGR098C 0.489558038 0.654810662 0.63877232 TEL2 -- telomere length regulation -- controlling telomere length and telomere position effect YGR198W YGR198W 0.4 17 1 0.2723 0.766342967 iYGR197C 0.442105925 0.920772187 0.584803854 YGR198W -- unknown -- unknown function YHR002W YHR002W 0.4 18 1 0.2723 0.568094407 iYHR001W-A 0.216657288 0.803192338 0.285368998 "YHR002W -- unknown -- similarity to Grave's disease protein, member of mitochondrial carrier (MCF) family of membrane transporters" YIR001C SGN1 0.4 16 1 0.2723 0.594706503 iYIR001C 0.644992299 0.483240223 0.75698812 "SGN1 -- unknown; growth on ethanol and glycerol -- possible role in respiratory growth, has one RNA recognition (RRM) domain" YJL021C YJL021C 0.4 17 1 0.2723 0.307638775 0.21969884 YJL021C -- unknown -- unknown function YJL044C GYP6 0.4 15 1 0.2723 0.520918156 iYJL044C 0.543826389 0.482939421 0.309619723 GYP6 -- secretion -- GTPase-activating protein for Ypt6p YJR107W YJR107W 0.4 16 1 0.2723 0.346191862 iYJR106W 0.516543752 0.451875499 0.461331145 "YJR107W -- unknown -- unknown function, has similarity to acylglycerol lipase" YLL003W SFI1 0.4 15 1 0.2723 0.528101656 iYLL004W 0.283463301 0.611518916 0.349252762 "SFI1 -- unknown -- cell cycle progression, suppressor of partial adenylate cyclase deficiency" YLR148W PEP3 0.4 15 1 0.2723 0.23827636 iYLR147C 0.299166727 0.740915444 0.179194503 PEP3 -- vacuole biogenesis -- Vacuolar peripheral membrane vacuolar protein sorting and required for vacuole biogenesis YLR193C YLR193C 0.4 18 1 0.2723 0.214757891 iYLR193C 0.259062589 0.550697749 0.174669675 YLR193C -- unknown -- Putative member of intramitochondrial sorting protein family YML111W BUL2 0.4 19 1 0.2723 0.457426403 iYML112W 0.229052015 0.329922027 0.399691358 "BUL2 -- protein degradation, ubiquitin-mediated (putative) -- similarity to Bul1p" YMR026C PEX12 0.4 15 1 0.2723 0.629181005 iYMR026C 0.591602721 0.265286513 0.200032914 PEX12 -- peroxisome biogenesis -- Peroxisomal biogenesis protein YMR193W MRPL24 0.4 17 1 0.2723 0.957332235 iYMR192W 0.597064903 0.617954415 0.289558134 MRPL24 -- protein synthesis -- Mitochondrial ribosomal large subunit (YmL24) YMR282C AEP2 0.4 17 1 0.2723 0.230278221 iYMR282C 0.572460001 0.777091413 0.862203956 AEP2 -- protein synthesis -- the expression of Atp9p YNL041C YNL041C 0.4 15 1 0.2723 0.397498553 iYNL041C 0.649701422 0.580538085 0.817031905 YNL041C -- unknown -- unknown function YNL051W YNL051W 0.4 15 1 0.2723 0.61398631 iYNL052W 0.500192355 0.875262055 0.549226555 "YNL051W -- unknown -- unknown function, contains a potential coiled-coil domain" YNL184C YNL184C 0.4 15 1 0.2723 0.529746974 iYNL184C 0.387206026 0.52956816 0.628733663 "YNL184C -- unknown -- unknown function, questionable ORF" YOR064C YNG1 0.4 15 1 0.2723 0.405892137 iYOR064C 0.237199197 0.361021592 0.122703835 "YNG1 -- unknown -- Component of histone acetyltransferase complex, has similarity to human retinoblastoma binding protein 2" YOR250C CLP1 0.4 18 1 0.2723 0.207421283 iYOR250C 0.138120985 0.562878116 0.076771168 "CLP1 -- mRNA 3'-end processing -- Subunit of cleavage and polyadenylation factor IA,required for 3'-end processing of pre-mRNA" YPL138C YPL138C 0.4 17 1 0.2723 0.473192852 iYPL138C 0.373629942 0.682179987 0.575578611 YPL138C -- unknown -- unknown function YPL180W YPL180W 0.4 16 1 0.2723 0.610115697 iYPL181W 0.455276503 0.166666667 0.572862668 YPL180W -- unknown -- unknown function YPL258C THI21 0.4 16 1 0.2723 0.204570739 iYPL258C YPLCdelta1 0.200088897 0.567580056 0.489123429 0.365652981 0.45580014 "THI21 -- thiamine metabolism (putative) -- Bipartite protein consisting of N-terminal hydroxymethylpyrimidine phosphate (HMP-P) kinase domain, needed for thiamine biosynthesis, fused to C-terminal Pet18p-like domain of indeterminant function" YPR022C YPR022C 0.4 17 1 0.2723 0.244477631 iYPR022C 0.520157624 0.092322883 0.645467836 "YPR022C -- unknown -- unknown function, contains two tandem C2H2-type zinc fingers" YPR189W SKI3 0.4 14 1 0.2723 0.287020504 iYPR188C 0.432707104 0.227550664 0.540050012 "SKI3 -- mRNA decay and virus resistance -- Antiviral tetratricopeptide (TPR) repeats, part of a system to protect cells from double-stranded RNA (dsRNA) viruses" YDL090C RAM1 0.3 12 1 0.2723 0.313610419 iYDL090C 0.202310112 0.518081761 0.350104822 "RAM1 -- protein processing -- farnesyltransferase (FTase), beta subunit" YDR506C YDR506C 0.3 13 1 0.2723 0.695604127 iYDR506C itL(CAA)D 0.526860837 0.703140625 0.950854012 0.599357891 0.887876099 YDR506C -- unknown -- similarity to Fet5p YEL076C-A YEL076C-A 0.3 16 1 0.2723 0.942146977 0.774788118 YEL076C-A -- unknown -- unknown function YER078C YER078C 0.3 14 1 0.2723 0.307923333 iYER078C 0.250992565 0.631045491 0.05204461 YER078C -- unknown -- similarity to E. coli X-Pro aminopeptidase II YGR021W YGR021W 0.3 11 1 0.2723 0.07468446 iYGR020C 0.247132131 0.333901884 0.23231427 "YGR021W -- unknown -- unknown function, likely involved in mitochondrial protein synthesis" YGR154C YGR154C 0.3 15 1 0.2723 0.746823762 iYGR154C 0.121372576 0.902477305 0.209001893 YGR154C -- unknown -- Putative paralog of Ecm4p YHR079C IRE1 0.3 10 1 0.2723 0.337077053 iYHR079C 0.581162475 0.390992588 0.283138402 "IRE1 -- protein folding -- kinase and type I membrane transmission of unfolded response (UPR) from the ER lumen to nucleus, site-specific endoribonuclease that acts on the HAC1 transcript to remove an intron" YIL134W FLX1 0.3 14 1 0.2723 0.776298594 iYIL135C SNR68 0.745264692 0.571946174 0.884950048 0.448172945 "FLX1 -- transport -- transport of FAD from cytosol into the mitochondrial matrix, member of mitochondrial carrier (MCF) family" YJL031C BET4 0.3 15 1 0.2723 0.617638245 iYJL031C 0.297070863 0.823505687 0.298268778 "BET4 -- protein processing -- Geranylgeranyltransferase Type II alpha subunit, complexes with Bet2p" YJL170C ASG7 0.3 14 1 0.2723 0.729174548 iYJL170C 0.378666365 0.688446665 0.634096816 ASG7 -- unknown -- expressed only in cells of mating type a YKL108W SLD2 0.3 13 1 0.2723 0.195740849 iYKL109W 0.390617577 0.390255511 0.248285876 SLD2 -- DNA replication -- DNA replication YKR044W YKR044W 0.3 13 1 0.2723 0.286894728 iYKR043C 0.144533921 0.313203989 0.313088587 YKR044W -- unknown -- unknown function YLL038C ENT4 0.3 13 1 0.2723 0.881023254 0.471348763 ENT4 -- endocytosis (putative) -- unknown function YLR133W CKI1 0.3 14 1 0.2723 0.238433323 iYLR132C 0.564014958 0.70466457 0.611376807 "CKI1 -- lipid metabolism -- Choline kinase, first step in CDP-choline biosynthesis pathway" YLR284C ECI1 0.3 12 1 0.2723 0.700042046 iYLR284C 0.455280746 0.876572327 0.526618848 "ECI1 -- unknown -- Peroxisomal 3,2-enoyl-CoA isomerase" YLR433C CNA1 0.3 13 1 0.2723 0.389497736 0.770720841 "CNA1 -- signaling -- Calcineurin catalytic (A) subunit, protein serine/threonine phosphatase 2B (PP2B), member of PPP family of protein phosphatases" YML104C MDM1 0.3 12 1 0.2723 0.244434861 iYML104C 0.66866249 0.780027426 0.743335994 MDM1 -- cytoskeletal organization -- Intermediate filament organelle inheritance and in the regulation of mitochondrial morphology YMR055C BUB2 0.3 13 1 0.2723 0.219018036 iYMR055C 0.555773724 0.778762488 0.542136642 "BUB2 -- cell cycle, checkpoint -- Checkpoint cell cycle arrest in response to loss of microtubule function" YMR179W SPT21 0.3 15 1 0.2723 0.111469179 iYMR178W 0.292066178 0.158260176 0.454702543 SPT21 -- transcription -- amplifies the magnitude of transcriptional regulation at various loci YNL042W BOP3 0.3 13 1 0.2723 0.249635746 iYNL043C YNLWsigma2 0.607668503 0.653233339 0.647126851 0.760223813 0.744096108 BOP3 -- unknown -- unknown function YNL133C YNL133C 0.3 12 1 0.2723 0.208939625 iYNL133C itF(GAA)N 0.522228475 0.062028022 0.06219427 0.475910409 0.067758329 YNL133C -- unknown -- unknown function YNL198C YNL198C 0.3 14 1 0.2723 0.679976049 iYNL198C 0.594260071 0.777328643 0.750359138 YNL198C -- unknown -- unknown function YOL078W YOL078W 0.3 11 1 0.2723 0.343973008 iYOL079W 0.835836649 0.211058998 0.18761691 YOL078W -- unknown -- unknown function YOL164W YOL164W 0.3 11 1 0.2723 0.356948766 iYOL165C iYOLCdelta1 0.90083039 0.794024345 0.731388978 0.890941357 0.36996455 YOL164W -- unknown -- similarity to Pseudomonas sp. alkyl sulfatase YOR013W YOR013W 0.3 11 1 0.2723 YOR013W -- unknown -- unknown function YOR040W GLO4 0.3 11 1 0.2723 0.674499341 iYOR039W 0.627049706 0.591779729 0.62140926 GLO4 -- methylglyoxal resistance -- Glyoxalase-II YOR129C YOR129C 0.3 14 1 0.2723 0.152131897 iYOR129C 0.32487933 0.260676376 0.632415638 YOR129C -- unknown -- unknown function YOR296W YOR296W 0.3 13 1 0.2723 0.28346327 iYOR295W 0.85999212 0.414535775 0.897187282 YOR296W -- unknown -- may be involved in bud-site selection YOR347C PYK2 0.3 12 1 0.2723 0.120080529 iYOR347C 0.807089106 0.204967895 0.747478785 "PYK2 -- glycolysis -- Pyruvate kinase, glucose-repressed isoform" YPL155C KIP2 0.3 14 1 0.2723 0.195177689 iYPL155C 0.386101232 0.356297696 0.150762281 KIP2 -- cytoskeleton (putative) -- Kinesin-related protein YPR031W YPR031W 0.3 13 1 0.2723 0.414972716 iYPR030W 0.639814356 0.63373515 0.615334633 YPR031W -- unknown -- similarity to human zinc finger protein PIR YDL104C QRI7 0.2 9 1 0.2723 0.219237774 iYDL104C 0.574839714 0.299793176 0.545859539 QRI7 -- unknown -- similarity to E. coli orfx gene YFL060C SNO3 0.2 9 1 0.2723 0.733405496 iYFL060C 0.270267725 0.854044834 0.062918448 "SNO3 -- unknown -- Putative pyridoxine (vitamin B6) biosynthetic enzyme with similarity to glutamine aminotransferases, has strong similarity to Sno1p and Sno2p" YKR090W YKR090W 0.2 11 1 0.2723 0.326170984 iYKR089C 0.678528709 0.438627294 0.661425577 "YKR090W -- unknown -- unknown function, contains two tandem LIM domains at the C-terminus" YOL003C YOL003C 0.2 11 1 0.2723 0.278578515 iYOL003C 0.210386687 0.838468758 0.309671695 YOL003C -- unknown -- unknown function YOR107W RGS2 0.2 10 1 0.2723 0.131265172 iYOR106W 0.531015139 0.284765898 0.475280629 RGS2 -- unknown -- Negative regulator of glucose-induced cAMP signaling pathway YNL011C YNL011C 0.4 19 0.9 0.2366 1 0.954378715 iYNL011C 0.967623943 0.899895136 0.422117996 YNL011C -- unknown -- unknown function YPL016W SWI1 0.4 18 0.9 0.2366 1 0.558905849 iYPL017C 0.983360545 0.166640064 0.179478906 "SWI1 -- transcription -- Component of SWI-SNF global transcription activator complex, acts to assist gene-specific activators through chromatin remodeling" YJL090C DPB11 0.3 14 0.9 0.2366 1 0.814265406 iYJL090C 0.975509344 0.735833998 0.577893057 DPB11 -- DNA replication -- DNA replication and an S-phase checkpoint function YPR161C SGV1 0.3 16 0.9 0.2366 1 0.919079913 iYPR161C 0.98810114 0.183338966 0.646793426 SGV1 -- cell cycle -- Serine/threonine protein kinase involved in pheromone adaptation pathway and in cell cycle YEL023C YEL023C 0.2 10 0.9 0.2366 1 0.907680252 iYEL023C 0.986360315 0.588775179 0.809018356 YEL023C -- unknown -- unknown function YCR039C ALPHA2 2.5 102 0.9 0.2366 0.99141287 iYCR039C 0.984495399 0.532549146 0.232972957 "ALPHA2 -- transcription -- Homeodomain regulatory protein Alpha2p, interacts with Mcm1p to repress a-specific genes and with A1p to repress haploid-specific genes" YKL010C UFD4 1.2 48 0.9 0.2366 0.436807458 iYKL010C 0.795549574 0.694621898 0.488385315 "UFD4 -- protein degradation, ubiquitin-mediated -- Probable ubiquitin-protein ligase E3 enzyme functioning in ubiquitin fusion degradation pathway" YCR070W 1 43 0.9 0.2366 YCR079W YCR079W 1 42 0.9 0.2366 0.192883562 iYCR077C 0.349354551 0.39695456 0.381564246 YCR079W -- unknown -- Protein phosphatase of PP2C family YOL155C YOL155C 1 42 0.9 0.2366 0.365624246 iYOL155C-0 iYOL155C-1 0.532755277 0.570156811 0.286831604 0.500120997 0.539969347 "YOL155C -- unknown -- similarity to S. cerevisiae glucan 1,4-alpha-glucosidase" YLR168C YLR168C 0.9 40 0.9 0.2366 0.703324593 iYLR168C 0.641054126 0.630035737 0.368375842 YLR168C -- unknown -- Protein possibly involved in intramitochondrial sorting YNL008C YNL008C 0.9 35 0.9 0.2366 0.51364415 iYNL008C 0.717638671 0.318435754 0.589185884 "YNL008C -- unknown -- similarity to Mdj2p, E. coli DnaJ, and other DnaJ-like proteins" YBR053C YBR053C 0.8 33 0.9 0.2366 0.413181967 iYBR053C-0 iYBR053C-1 0.346370596 0.570428566 0.710534717 0.840799227 0.921548284 YBR053C -- unknown -- similarity to rat calcium-binding protein regucalcin and rat senescence marker protein 30 YDR206W EBS1 0.8 35 0.9 0.2366 0.681803464 iYDR205W 0.492079506 0.871887593 0.650506639 "EBS1 -- unknown -- similarity to Est1p, involved in maintenance of telomeres, contains an RNA recognition (RRM) domain" YHR216W YHR216W 0.8 32 0.9 0.2366 0.971154195 iYHR215W 0.757439055 0.668572095 0.230663874 YHR216W -- purine biosynthesis -- Inosine-5'-monophosphate dehydrogenaseconverts inosine 5'-phosphate and NAD(+) to xanthosine 5'-phosphate and NADH YIL049W DFG10 0.8 32 0.9 0.2366 0.317593094 iYIL050W 0.578899911 0.936229738 0.564534322 "DFG10 -- filamentous growth -- filamentous growth, cell polarity, and cellular elongation" YKL043W PHD1 0.8 31 0.9 0.2366 0.437750916 iYKL044W 0.059866057 0.505027933 0.052177336 PHD1 -- pseudohyphal growth -- Transcription factor involved in regulation of filamentous growth YLL053C AQY2 0.8 30 0.9 0.2366 0.09266838 0.171769256 "AQY2 -- unknown -- Aquaporin water channel protein, member of major intrinsic protein (MIP) family of transmembrane channels, has strong similarity to aquaporin Aqy1p" YMR252C YMR252C 0.8 33 0.9 0.2366 0.428644463 iYMR252C 0.262824513 0.584994931 0.556079665 YMR252C -- unknown -- unknown function YNL274C YNL274C 0.8 34 0.9 0.2366 0.578904768 iYNL274C 0.142126182 0.897605746 0.175347651 YNL274C -- unknown -- Potential alpha-ketoisocaproate reductase YOL048C YOL048C 0.8 31 0.9 0.2366 0.561965483 iYOL048C 0.120057788 0.759096816 0.286786418 YOL048C -- unknown -- unknown function YPL242C IQG1 0.8 30 0.9 0.2366 0.505117059 iYPL242C 0.62177393 0.466455491 0.306184522 "IQG1 -- cytoskeleton -- cytokinesis, has similarity to mammalian IQGAP proteins" YDL035C GPR1 0.7 27 0.9 0.2366 0.61244592 0.333595388 "GPR1 -- signaling, pheromone pathway -- G-protein coupled receptor coupled to Gpa2p, involved in the pathway of pseudohyphal differention in response to nutrient starvation" YDL180W YDL180W 0.7 31 0.9 0.2366 0.342956992 iYDL181W 0.336433339 0.693738172 0.429753951 YDL180W -- unknown -- unknown function YDR283C GCN2 0.7 26 0.9 0.2366 0.393920043 iYDR283C 0.552193123 0.784588417 0.720975299 GCN2 -- protein synthesis -- Serine/threonine protein kinase that regulates initiation of translation by phosphorylation of eIF2alpha (Sui2p) YDR486C YDR486C 0.7 32 0.9 0.2366 0.345526168 iYDR486C 0.427091781 0.332242618 0.23364486 YDR486C -- unknown -- similarity to Snf7p YER182W YER182W 0.7 24 0.9 0.2366 0.692276268 iYER181C YERCdelta26 0.221191648 0.366181712 0.966443494 0.159039639 0.338626858 YER182W -- unknown -- unknown function YGL166W CUP2 0.7 27 0.9 0.2366 0.27345026 iYGL167C 0.378854295 0.801563004 0.693063678 "CUP2 -- transcription -- Copper-dependent transcription factor responsible for induction of CUP1A, CUP1B, CRS5, and SOD1" YGR144W THI4 0.7 28 0.9 0.2366 0.422737667 iYGR143W iYGRCdelta25 0.425705762 0.706226816 0.766731644 0.419229469 0.220834676 THI4 -- thiamine biosynthesis -- Thiamine-repressed protein essential for growth in the absence of thiamine YIL036W CST6 0.7 25 0.9 0.2366 0.337988146 iYIL037C 0.582909831 0.505137052 0.718820496 "CST6 -- unknown -- similarity to Mei4p and to cAMP response element binding proteins, overproduction causes chromosome instability and increased mitotic recombination" YKL193C SDS22 0.7 26 0.9 0.2366 0.504701483 iYKL193C 0.092161696 0.776909442 0.039558492 SDS22 -- glucose repression -- Regulatory subunit for Glc7p type I protein serine/threonine phosphatasehas a mitotic function YOR044W YOR044W 0.7 27 0.9 0.2366 0.759867825 iYOR043W 0.764187752 0.815358554 0.332096475 YOR044W -- unknown -- unknown function YOR221C MCT1 0.7 28 0.9 0.2366 0.671813826 iYOR221C 0.451293249 0.559055752 0.509421542 MCT1 -- fatty acid metabolism -- Malonyl CoA YPL250C YPL250C 0.7 29 0.9 0.2366 0.536726216 iYPL250C YPL249C-A 0.51443042 0.920005053 0.312600709 0.110062893 0.408556236 "YPL250C -- unknown -- unknown function, transcription induced by the drug FK506 in a GCN4-dependent manner" YBL034C STU1 0.6 21 0.9 0.2366 0.708893909 iYBL034C 0.45781142 0.555994199 0.596960168 STU1 -- mitosis -- Suppressor of beta-tubulin mutation that is required for assembly of mitotic spindle YBR050C REG2 0.6 20 0.9 0.2366 0.512843016 0.713815519 REG2 -- glucose repression -- Possible regulatory subunit for the PP1 family protein phosphatase Glc7p YBR231C AOR1 0.6 20 0.9 0.2366 0.935624299 iYBR231C 0.360232423 0.045695832 0.018867925 AOR1 -- unknown -- unknown function YDL115C YDL115C 0.6 26 0.9 0.2366 0.278148803 iYDL115C 0.264362105 0.17925601 0.387345679 YDL115C -- unknown -- unknown function YDR142C PEX7 0.6 22 0.9 0.2366 0.250451393 iYDR142C 0.3267331 0.429523574 0.370170202 "PEX7 -- peroxisome biogenesis -- Peroxisomal biogenesis protein (peroxin) that serves as import receptor for proteins containing peroxisomal targeting signal 2 (PTS2), member of WD (WD-40) repeat family" YDR524C AGE1 0.6 23 0.9 0.2366 0.454430994 iYDR524C 0.856616742 0.50698812 0.653158234 AGE1 -- unknown -- ADP-ribosylation factor (ARF) GTPase activating protein (GAP) with effector functions YER108C 0.6 21 0.9 0.2366 YER143W DDI1 0.6 24 0.9 0.2366 0.418021289 iYER142C 0.366716823 0.811093376 0.274500123 DDI1 -- unknown -- binds to t- and v-SNARE complexes YER157W SEC34 0.6 23 0.9 0.2366 0.813282717 iYER156C 0.238641273 0.878262971 0.390106349 SEC34 -- secretion -- retention of proteins in the Golgi apparatus YGR072W UPF3 0.6 23 0.9 0.2366 0.1182329 iYGR071C 0.362776588 0.152133581 0.330806065 "UPF3 -- mRNA decay, nonsense-mediated -- involved with Nam7p and Nmd2p in decay of mRNA containing nonsense codons" YHR049C-A YHR049C-A 0.6 24 0.9 0.2366 0.538577111 iYHR049C-A 0.602660057 0.26915165 0.640462889 YHR049C-A -- unknown -- unknown function YIL031W ULP2 0.6 22 0.9 0.2366 0.517694504 iYIL032C 0.389152196 0.528039832 0.152428372 "ULP2 -- unknown -- Smt3p-specific protease, degrades conjugated ubiquitin-like protein Smt3p" YIR036C YIR036C 0.6 24 0.9 0.2366 0.496083025 iYIR036C 0.459906116 0.76225076 0.223386279 YIR036C -- unknown -- similarity to proteins of short-chain alcohol dehydrogenase family and to 7-alpha-hydroxysteroid dehydrogenase YJR122W CAF17 0.6 22 0.9 0.2366 0.942489234 iYJR121W 0.760982917 0.634397446 0.545924763 CAF17 -- catabolite repression -- Component of CCR4 transcription complexhas positive and negative effects on transcription YKL025C PAN3 0.6 20 0.9 0.2366 0.34050638 iYKL025C 0.416709556 0.499072356 0.382852862 PAN3 -- mRNA processing -- Component of Pab1p-stimulated poly(A) ribonuclease YKR067W YKR067W 0.6 24 0.9 0.2366 0.494493325 iYKR066C 0.559358887 0.585155626 0.923557969 YKR067W -- unknown -- similarity to Sct1p YLR219W YLR219W 0.6 21 0.9 0.2366 0.234780231 iYLR218C 0.501014858 0.265307767 0.173268087 YLR219W -- unknown -- unknown function YMR255W GFD1 0.6 22 0.9 0.2366 0.085691157 iYMR254C 0.474592522 0.13173702 0.189999866 "GFD1 -- RNA processing (putative) -- nuclear pore complex that associates with Gle1p, Nup42p, and Dbp5pmay be involved in mRNA export" YNL047C YNL047C 0.6 23 0.9 0.2366 0.225920172 iYNL047C 0.320122196 0.609405458 0.30922609 YNL047C -- unknown -- similarity to Ask10p YNL059C ARP5 0.6 23 0.9 0.2366 0.123284856 iYNL059C 0.330718032 0.385296941 0.518871112 ARP5 -- cytoskeleton (putative) -- Actin-related protein YNL072W RNH35 0.6 21 0.9 0.2366 0.118435342 iYNL073W 0.488818557 0.617165443 0.151559454 "RNH35 -- DNA replication (putative) -- Ribonuclease H, endonuclease that degrades RNA in RNA-DNA hybrids" YOL018C TLG2 0.6 24 0.9 0.2366 0.110247693 iYOL018C 0.296999531 0.310505962 "TLG2 -- endocytosis -- Syntaxin homolog (t-SNARE), involved in efficient endocytosis and in maintenance of resident proteins in the trans-Golgi network" YOL034W YOL034W 0.6 22 0.9 0.2366 0.333538822 iYOL035C SNR50 0.594941747 0.867863443 0.583000798 0.445580014 0.418291098 "YOL034W -- unknown -- Putative coiled-coil protein, has similarity to members of S. pombe SMC (structural maintenance of chromosomes) family" YOR093C YOR093C 0.6 21 0.9 0.2366 0.512937586 iYOR093C 0.589891508 0.583896587 0.610587002 YOR093C -- unknown -- unknown function YOR147W YOR147W 0.6 22 0.9 0.2366 0.297039807 iYOR146W 0.382137436 0.673308058 0.30474334 YOR147W -- unknown -- unknown function YPL084W BRO1 0.6 23 0.9 0.2366 0.212357131 iYPL085W 0.155895304 0.355569896 0.124811949 BRO1 -- unknown -- interacts with components of PKC1-MAP kinase pathway YPL238C YPL238C 0.6 23 0.9 0.2366 0.154685176 0.090155945 YPL238C -- unknown -- unknown function YPL270W MDL2 0.6 22 0.9 0.2366 0.104387756 iYPL271W 0.183696439 0.131683958 0.152720474 "MDL2 -- transport -- Member of ATP-binding cassette (ABC) superfamily, equivalent to a ""half-sized"" ABC protein" YAR066W YAR066W 0.4 17 0.9 0.2366 0.323859727 iYAR064W 0.605859509 0.202952327 0.420590583 YAR066W -- unknown -- unknown function YBR161W YBR161W 0.4 19 0.9 0.2366 0.235069163 iYBR160W 0.234394532 0.602726466 0.307090425 "YBR161W -- unknown -- similarity to Sur1p, Hoc1p, and Och1p" YCL029C BIK1 0.4 17 0.9 0.2366 0.590045942 iYCL029C 0.4459963 0.083145343 0.389040343 BIK1 -- mating; mitosis -- Microtubule-associated microtubule function during mitosis and mating YDL109C YDL109C 0.4 16 0.9 0.2366 0.869723868 iYDL109C 0.522053016 0.264616424 0.547595841 "YDL109C -- unknown -- unknown function, has strong similarity to Ydr444p and Ygl144p" YDR057W YDR057W 0.4 20 0.9 0.2366 0.575198316 iYDR056C 0.733608548 0.432404125 0.853190288 "YDR057W -- unknown -- unknown function, has a C-terminal HDEL endoplasmic retention sequence" YDR073W SNF11 0.4 19 0.9 0.2366 0.620197733 iYDR072C 0.501691559 0.769516729 0.548567435 SNF11 -- transcription -- Component of SWI-SNF global transcription activator complexacts to assist gene-specific activators through chromatin remodeling YDR338C YDR338C 0.4 19 0.9 0.2366 0.345221382 iYDR338C 0.832788957 0.776433802 0.911690143 YDR338C -- unknown -- Member of multiple antimicrobiotic resistance (MAR) family of membrane transporters YER119C YER119C 0.4 20 0.9 0.2366 0.555475907 0.926248039 YER119C -- unknown -- Membrane transporter of amino acid/auxin permease (AAAP) family YER132C PMD1 0.4 20 0.9 0.2366 0.354946864 iYER132C SNR52 0.406371807 0.740996484 0.640831453 0.156257714 0.489066241 PMD1 -- meiosis -- negative regulation of early meiotic gene expression YFR014C CMK1 0.4 18 0.9 0.2366 0.440349199 iYFR014C 0.351070661 0.459228174 0.205043506 CMK1 -- signaling -- Calcium/calmodulin-dependent serine/threonine protein kinase (CaM kinase) type I YGL047W YGL047W 0.4 19 0.9 0.2366 0.672300661 iYGL048C 0.190391532 0.803556064 0.129449322 YGL047W -- unknown -- similarity to Plasmodium falciparum gametocytogenesis onset-specific protein YGL117W YGL117W 0.4 16 0.9 0.2366 0.906786143 iYGL118C 0.324778981 0.946350118 0.107929338 YGL117W -- unknown -- unknown functiontranscription induced by the drug FK506 in a GCN4-dependent manner YGL185C YGL185C 0.4 16 0.9 0.2366 0.292233976 iYGL185C 0.409340289 0.813067785 0.248872059 YGL185C -- unknown -- similarity to D-2-hydroxyacid dehydrogenase YGL241W KAP114 0.4 18 0.9 0.2366 0.490450465 iYGL242C 0.067101748 0.852890109 0.034591195 "KAP114 -- nuclear protein targeting -- karyopherin-beta family, involved in Spt15p nuclear import" YGR048W UFD1 0.4 20 0.9 0.2366 0.597982555 iYGR047C 0.40001728 0.916441075 0.411456573 "UFD1 -- protein degradation, ubiquitin-mediated -- Ubiquitin fusion degradation protein" YHR117W TOM72 0.4 18 0.9 0.2366 0.290754122 iYHR116W 0.012394646 0.612688225 "TOM72 -- mitochondrial protein targeting -- similarity to Tom70p/Mas70p, has tetratricopeptide (TPR) repeats" YHR134W YHR134W 0.4 18 0.9 0.2366 0.232086372 iYHR133C 0.488321835 0.743916864 0.567391394 YHR134W -- unknown -- unknown function YIL026C IRR1 0.4 17 0.9 0.2366 0.381518618 iYIL026C 0.373569826 0.631923384 0.412204329 IRR1 -- unknown -- Component of cohesin complexrequired for sister chromatid cohesion during DNA replication YIL050W PCL7 0.4 20 0.9 0.2366 0.631568971 iYIL051C 0.674384276 0.795530726 0.49886443 "PCL7 -- cell cycle -- Cyclin, associates with Pho85p" YIL162W SUC2 0.4 19 0.9 0.2366 0.504350923 iYIL163C 0.650148962 0.946049481 0.293022181 "SUC2 -- sucrose utilization -- Beta-fructofuranosidase 2, invertase" YIL164C NIT1 0.4 17 0.9 0.2366 0.154448085 iYIL164C-0 iYIL164C-1 0.462778625 0.268871186 0.283193571 0.267949968 0.383647799 "NIT1 -- unknown -- similarity to nitrilases, may be a pseudogene or separated from YIL165C by sequencing errors" YJL108C YJL108C 0.4 18 0.9 0.2366 0.661012715 0.969428087 YJL108C -- unknown -- unknown function YJL141C YAK1 0.4 20 0.9 0.2366 0.353202344 iYJL141C 0.289284931 0.376935355 0.386303138 "YAK1 -- signaling -- Serine/threonine protein kinase, negative regulator of cell growth acting in opposition to cAMP-dependent protein kinase A" YJR090C GRR1 0.4 18 0.9 0.2366 0.387040192 iYJR090C 0.052969773 0.49704292 0.08958692 "GRR1 -- glucose repression (and cell cycle) -- F-box targets G1 cyclins and Gic1p and other proteins for degradation by the SCF-Grr1p complex (Skp1p-Cdc53p-Cdc34p-Grr1p), also required for glucose repression and for glucose and cation transport" YJR151C YJR151C 0.4 17 0.9 0.2366 0.292734852 iYJR151C-0 iYJR151C-1 0.33763797 0.400780388 0.049145988 0.715237167 0.818788848 YJR151C -- unknown -- Member of seripauperin (PAU) family of possible cell wall mannoproteins YKL033W YKL033W 0.4 17 0.9 0.2366 0.700085522 YKL033W-A iYKL033W-A 0.669136313 0.866550983 0.800316717 0.519964508 0.82286215 YKL033W -- unknown -- unknown function YKL105C YKL105C 0.4 19 0.9 0.2366 0.117122031 iYKL105C 0.287342006 0.122346369 0.406469307 YKL105C -- unknown -- unknown function YLL058W YLL058W 0.4 17 0.9 0.2366 0.577019147 iYLL059C 0.528945398 0.781421205 0.551738142 YLL058W -- unknown -- similarity to Neurospora crassa O-succinylhomoserine (thiol)-lyase YLR116W MSL5 0.4 17 0.9 0.2366 0.227823499 iYLR115W 0.50538214 0.220119505 0.580525356 MSL5 -- mRNA splicing -- Component of splicing commitment complex involved in recognition of branchpoint sequence and in bridging the ends of intron YLR119W SRN2 0.4 19 0.9 0.2366 0.212673315 iYLR118C 0.741149933 0.257653883 0.433814633 "SRN2 -- RNA export, putative -- Suppressor of rna1-1 mutant" YLR245C CDD1 0.4 18 0.9 0.2366 0.368962359 iYLR245C 0.491133442 0.786432562 0.752658717 CDD1 -- pyrimidine metabolism -- Cytidine deaminase YLR373C VID22 0.4 16 0.9 0.2366 0.123593302 iYLR373C 0.064673446 0.412639405 0.051981806 "VID22 -- unknown -- Plasma membrane associated targeting of fructose-1,6-bisphosphatase to Vid vesicles, has weak similarity to Von Willebrand factor" YLR439W MRPL4 0.4 17 0.9 0.2366 0.507131997 YLR438C-A iYLR438C-A 0.317122293 0.395875868 0.313372478 0.083320032 0.020982473 MRPL4 -- protein synthesis -- Mitochondrial ribosomal large subunit YMR078C CTF18 0.4 19 0.9 0.2366 0.324807751 iYMR078C 0.482929292 0.695147013 0.54769392 "CTF18 -- mitosis, chromosome transmission -- accurate chromosome transmission in mitosis and maintenance of normal telomere lengthhomolog of Rfc1p, Rfc2p, Rfc3p, Rfc4p, and Rfc5p" YMR281W GPI12 0.4 19 0.9 0.2366 0.497282279 iYMR280C 0.578205364 0.936069844 0.893867925 "GPI12 -- protein processing (putative) -- N-acetylglucosaminyl phosphatidylinositol deacetylase, second step in glycosylphosphatidylinositol (GPI) biosynthesis" YNL176C YNL176C 0.4 18 0.9 0.2366 0.135139481 iYNL176C 0.43821792 0.346653671 0.530407023 YNL176C -- unknown -- unknown function YNL278W YNL278W 0.4 16 0.9 0.2366 0.12259828 iYNL279W 0.435151911 0.255067837 0.280671439 YNL278W -- unknown -- unknown function YNR049C MSO1 0.4 18 0.9 0.2366 0.254363887 iYNR049C 0.537433933 0.569618114 0.74398336 MSO1 -- secretion -- Probable component of secretory vesicle docking complexfunctions in association with Sec1p YOR030W DFG16 0.4 20 0.9 0.2366 0.428738308 iYOR029W-0 iYOR029W-1 0.021921384 0.72664162 0.344302362 0.23420883 0.743414787 DFG16 -- invasive growth -- invasive growth upon nitrogen starvation YOR090C PTC5 0.4 20 0.9 0.2366 0.298412425 iYOR090C 0.452177831 0.564884278 0.334876297 PTC5 -- unknown -- Putative serine/threonine protein phosphatase of PP2C family YOR292C YOR292C 0.4 18 0.9 0.2366 0.981623612 iYOR292C 0.987197368 0.339175512 0.343378756 YOR292C -- unknown -- unknown function YPL003W ULA1 0.4 19 0.9 0.2366 0.59008494 iYPL004C 0.349786946 0.65235435 0.297344514 "ULA1 -- protein degradation, Rub1p-mediated -- Rub1-activating enzyme, similar to ubiquitin-activating E1-like proteins" YPL069C BTS1 0.4 17 0.9 0.2366 0.586349364 iYPL069C 0.741060666 0.929130088 0.773309989 BTS1 -- protein processing -- Geranylgeranyl diphosphate synthase YPL103C YPL103C 0.4 18 0.9 0.2366 0.07634102 iYPL103C 0.415605607 0.157654613 0.757590718 YPL103C -- unknown -- unknown function YPL196W YPL196W 0.4 21 0.9 0.2366 0.389357131 iYPL197C 0.537927615 0.495211492 0.363048683 YPL196W -- unknown -- unknown function YPR025C CCL1 0.4 20 0.9 0.2366 0.167674916 iYPR025C 0.53341201 0.281432749 0.585866527 "CCL1 -- transcription -- Cyclin C component of RNA polymerase transcription initiation factor TFIIHrequired for PolII transcription, for nucleotide excision repair, and for activity of Kin28p" YPR044C 0.4 16 0.9 0.2366 0.895541251 iYPR044C 0.747747016 0.800319234 0.403888037 YPR079W YPR079W 0.4 20 0.9 0.2366 0.975398481 iYPR078C 0.663966903 0.435097834 0.173300032 YPR079W -- unknown -- unknown function YPR084W YPR084W 0.4 21 0.9 0.2366 0.257770492 iYPR083W 0.547858222 0.498066387 0.255163334 YPR084W -- unknown -- unknown function YPR162C ORC4 0.4 19 0.9 0.2366 0.958720499 iYPR162C 0.766058365 0.869726547 0.394622996 "ORC4 -- DNA replication -- Origin recognition complex (ORC), 56 kDa subunit" YPR203W YPR203W 0.4 20 0.9 0.2366 0.935171768 0.324421389 YPR203W -- unknown -- similarity to other subtelomerically-encoded proteins YBL008W HIR1 0.3 14 0.9 0.2366 0.454019939 iYBL009W 0.556778105 0.544970557 0.656627993 "HIR1 -- transcription -- Histone transcription inhibitor, required for periodic repression of 3 of 4 histone gene loci and for autogenous repression of HTA1-HTB1 locus by H2A and H2B, member of WD (WD-40) repeat family" YBL009W YBL009W 0.3 16 0.9 0.2366 0.463667748 iYBL010C 0.833076236 0.682916526 0.552046407 YBL009W -- unknown -- unknown function YBL029W YBL029W 0.3 14 0.9 0.2366 0.664125707 iYBL030C-0 iYBL030C-1 0.772236947 0.946168319 0.358018596 0.648069961 0.513618037 "YBL029W -- unknown -- unknown function induced during anaerobic growth, has a leucine zipper" YDL077C VAM6 0.3 15 0.9 0.2366 0.75653308 iYDL077C 0.530428394 0.448737598 0.440789474 VAM6 -- protein degradation -- the last step of vacuolar assembly YDR004W RAD57 0.3 13 0.9 0.2366 0.475501665 iYDR003W 0.441323521 0.626735834 0.799593322 "RAD57 -- DNA repair and recombination -- Component of recombinosome complex involved in meiotic recombination and recombinational repair, with Rad55p promotes DNA strand exchange by Rad51p recombinase" YDR030C RAD28 0.3 14 0.9 0.2366 0.45183291 iYDR030C 0.284867273 0.501572327 0.194044702 "RAD28 -- DNA repair -- the same pathway as Rad26p, has WD (WD-40) repeats" YDR123C INO2 0.3 15 0.9 0.2366 0.15744841 iYDR123C 0.166241562 0.293836913 0.366799681 INO2 -- phospholipid biosynthesis -- Basic helix-loop-helix (bHLH) transcription factor required for derepression of phospholipid synthetic genes YDR183W PLP1 0.3 15 0.9 0.2366 0.168056596 iYDR182W 0.273889025 0.704788508 0.260100387 PLP1 -- unknown -- Phosducin homologue likely to be involved in regulation of pheromone response YDR197W CBS2 0.3 16 0.9 0.2366 0.707684222 iYDR196C 0.398655905 0.801643571 0.239977414 "CBS2 -- protein synthesis -- Mitochondrial translational activator, acts specifically on the COB mRNA encoding cytochrome b" YDR315C IPK1 0.3 16 0.9 0.2366 0.415349878 iYDR315C 0.162535118 0.760022586 0.230327215 "IPK1 -- signaling (putative) -- Inositol 1,3,4,5,6-pentakisphosphate (IP5) kinase" YDR375C BCS1 0.3 15 0.9 0.2366 0.678337467 iYDR375C 0.443588912 0.995195667 0.480622069 "BCS1 -- respiration -- Mitochondrial expression of functional Rieske iron-sulfur protein, member of AAA family of ATPases" YEL004W YEA4 0.3 15 0.9 0.2366 0.562813664 iYEL005C 0.673686345 0.896486464 0.595191683 YEA4 -- unknown -- similarity to K. lactis UDP-N-acetylglucosamine transporter YEL016C YEL016C 0.3 13 0.9 0.2366 0.220133135 iYEL016C 0.452469332 0.520717037 0.661376088 YEL016C -- unknown -- similarity to Ycr026p YER093C-A YER093C-A 0.3 15 0.9 0.2366 0.237882545 iYER093C-A 0.363115296 0.379713181 0.140407857 YER093C-A -- unknown -- unknown function YER142C MAG1 0.3 14 0.9 0.2366 0.474388264 iYER142C 0.366716823 0.704926625 0.274500123 "MAG1 -- DNA repair -- DNA-3-methyladenine glycosylaseexcises 3-methyladenine, 7-methyladenine, 3-methylguanine and 7-methylguanine from alkylation-damaged DNA" YER189W YER189W 0.3 13 0.9 0.2366 0.978742156 YERWomega2 iYERWomega2-0 0.832899453 0.997571637 0.89041906 0.459952687 0.0203835 "YER189W -- unknown -- similarity to subtelomerically-encoded proteins including Yil177p, Yhl049p, and Yjl225p" YGL064C YGL064C 0.3 13 0.9 0.2366 0.414737528 iYGL064C 0.65038292 0.863514023 0.516406758 YGL064C -- unknown -- member of DEAD-box RNA helicase family YGL128C YGL128C 0.3 13 0.9 0.2366 0.000323782 0.906725245 YGL128C -- unknown -- similarity to E. coli DnaJ and other DnaJ-like proteins YGL236C MTO1 0.3 15 0.9 0.2366 0.374210782 "MTO1 -- salt tolerance (putative) -- role in mitochondrial translational accuracy, has strong similarity to E. coli gidA protein" YGR075C PRP38 0.3 15 0.9 0.2366 0.561383324 iYGR075C 0.413572666 0.821069433 0.680446927 "PRP38 -- mRNA splicing -- pre-mRNA splicing, involved in U4/U6 snRNA dissociation before U6 snRNA integration into the splicosome active site" YGR100W MDR1 0.3 14 0.9 0.2366 0.257784547 iYGR099W 0.329557608 0.535275339 0.332420238 MDR1 -- unknown -- GTPase-activating protein for Ypt6p and Sec4p YHR120W MSH1 0.3 12 0.9 0.2366 0.36038018 iYHR119W 0.684214869 0.440055953 0.340237167 MSH1 -- DNA repair -- mitochondrial DNA repairhomolog of E. coli MutS YHR164C DNA2 0.3 13 0.9 0.2366 0.586497046 iYHR164C 0.153072301 0.346569787 0.253061553 "DNA2 -- DNA replication -- DNA helicase, ssDNA-dependent ATPase, and ATP-dependent endonuclease activities" YIL082W-A 0.3 15 0.9 0.2366 0.071860843 YILWTy3-1B YILWTy3-1C 0.025346105 0.037183937 0.183398311 0.015025991 0.050569624 YIL141W YIL141W 0.3 14 0.9 0.2366 0.505799407 iYIL142W 0.471049961 0.682100508 0.499650594 YIL141W -- unknown -- unknown functionquestionable ORF YIR010W YIR010W 0.3 15 0.9 0.2366 0.232623579 iYIR009W 0.54963169 0.375974659 0.666854884 YIR010W -- unknown -- Essential unknown function YJL003W YJL003W 0.3 13 0.9 0.2366 0.442641537 iYJL004C 0.440914259 0.509990253 0.73565904 YJL003W -- unknown -- unknown function YJL131C YJL131C 0.3 14 0.9 0.2366 0.336975878 iYJL131C 0.374354661 0.740253411 YJL131C -- unknown -- similarity to carbamylphosphate synthetase YJL137C GLG2 0.3 16 0.9 0.2366 0.737247637 iYJL137C 0.647743213 0.670616309 0.253581412 GLG2 -- glycogen metabolism -- Self-glucosylating initiator of glycogen synthesis YJR127C ZMS1 0.3 12 0.9 0.2366 0.620599434 0.693312898 "ZMS1 -- unknown -- similarity to Adr1p and Yml081p, has two tandem zinc finger domains" YKL201C MNN4 0.3 15 0.9 0.2366 0.532799736 0.569931774 MNN4 -- protein glycosylation -- transfer of mannosylphosphate to core and outer chain portions of N-linked oligosaccharides YKR022C YKR022C 0.3 13 0.9 0.2366 0.091406062 iYKR022C 0.220756266 0.253005198 0.389146049 YKR022C -- unknown -- unknown function YKR063C LAS1 0.3 13 0.9 0.2366 0.148724537 iYKR063C 0.277313172 0.206017585 0.50068565 "LAS1 -- morphogenesis, cytoskeletal assembly, bud formation -- cell morphogenesis, cytoskeletal regulation, and bud formation" YKR086W PRP16 0.3 14 0.9 0.2366 0.302955584 iYKR085C 0.326876682 0.47067839 0.369234801 PRP16 -- mRNA splicing -- Pre-mRNA splicing factor and an ATP-dependent RNA helicase of DEAH box family YLR152C YLR152C 0.3 13 0.9 0.2366 0.272052602 iYLR152C 0.464418556 0.522061789 0.704883407 YLR152C -- unknown -- similarity to Ecm3p YLR353W BUD8 0.3 15 0.9 0.2366 0.207194995 iYLR352W 0.304345175 0.470436396 0.388648049 "BUD8 -- bud site selection, bipolar -- bipolar budding, has an RNA recognition (RRM) domain" YLR386W YLR386W 0.3 13 0.9 0.2366 0.465982426 iYLR385C 0.209421979 0.524805373 0.374010776 YLR386W -- unknown -- unknown function YLR411W CTR3 0.3 15 0.9 0.2366 0.315842937 iYLRWdelta23 0.439716146 0.838946528 0.473902634 CTR3 -- transport -- High-affinity copper transporter YLR462W YLR462W 0.3 15 0.9 0.2366 0.973246692 iYLR461W-0 iYLR461W-1 0.995599358 0.997619024 0.92240599 0.171296296 0.364804469 YLR462W -- unknown -- unknown function YML020W YML020W 0.3 14 0.9 0.2366 0.345860502 iYML021C 0.166907566 0.202810266 0.064047753 YML020W -- unknown -- unknown function YMR273C ZDS1 0.3 12 0.9 0.2366 0.483520685 iYMR273C 0.031022744 0.172352177 0.029350105 "ZDS1 -- cell cycle -- regulates SWE1 and CLN2 transcription, Sir3p phosphorylation, rDNA recombination and silencing, and life span" YMR283C RIT1 0.3 15 0.9 0.2366 0.274635443 iYMR283C YMRWdelta21 0.212746981 0.652932728 0.829759584 0.412118259 0.829589402 RIT1 -- tRNA processing -- Initiator tRNA phosphoribosyl-transferasemodifies tRNA backbone and mediates discrimination between initiator and elongator tRNA YNL148C ALF1 0.3 13 0.9 0.2366 0.244339779 iYNL148C 0.285741962 0.361862116 0.336093275 "ALF1 -- protein folding -- Alpha-tubulin foldin, cofactor B" YNL227C YNL227C 0.3 12 0.9 0.2366 0.119783444 0.142211825 "YNL227C -- unknown -- Member of DnaJ of molecular chaperones, contains two C2H2-type zinc fingers" YNL275W YNL275W 0.3 15 0.9 0.2366 0.284065374 iYNL276C 0.487849138 0.610054786 0.252969951 YNL275W -- unknown -- similarity to human band 3 anion transport protein YNR008W LRO1 0.3 11 0.9 0.2366 0.250006509 iYNR007C 0.195260294 0.60514333 0.106830887 "LRO1 -- sterol metabolism (putative) -- Diacylglycerol acyltransferase, has similarity to lecithin cholesterol acyl transferase (phosphatidylcholine-sterol O-acyltransferase)" YOL076W MDM20 0.3 14 0.9 0.2366 0.303620657 iYOL077C 0.342022386 0.672091524 0.272896249 MDM20 -- mitochondrial inheritance; actin assembly -- interacts genetically with Cin8p YOL107W YOL107W 0.3 15 0.9 0.2366 0.391496971 iYOL108C 0.483012777 0.665204678 0.294577471 YOL107W -- unknown -- similarity to Rnh70p and Pan2p YOR025W HST3 0.3 14 0.9 0.2366 0.153067832 HST3 -- silencing -- similarity to Sir2p YOR060C YOR060C 0.3 15 0.9 0.2366 0.208838225 iYOR060C 0.39952033 0.272646608 0.227438112 YOR060C -- unknown -- unknown function YOR169C YOR169C 0.3 16 0.9 0.2366 0.848197082 0.870931357 YOR169C -- unknown -- unknown function YOR218C YOR218C 0.3 14 0.9 0.2366 0.252660472 iYOR218C 0.441921879 0.467105263 0.403316252 YOR218C -- unknown -- unknown function YOR284W YOR284W 0.3 13 0.9 0.2366 0.408521391 iYOR283W 0.401867375 0.6302805 0.485497905 YOR284W -- unknown -- unknown function YOR337W TEA1 0.3 12 0.9 0.2366 0.831342445 iYOR336W 0.714394439 0.461730583 0.66919416 TEA1 -- transcription -- Ty1 enhancer activator of Gal4p-type family of DNA-binding proteins YPL083C SEN54 0.3 12 0.9 0.2366 0.415410254 iYPL083C 0.313815479 0.664840477 0.275873195 "SEN54 -- tRNA splicing -- tRNA splicing endonuclease, alpha subunit" YPL099C YPL099C 0.3 14 0.9 0.2366 0.057776048 iYPL099C 0.412756151 0.147012579 0.395467836 YPL099C -- unknown -- unknown function YPL193W RSA1 0.3 14 0.9 0.2366 0.466781479 iYPL194W 0.110228767 0.356993232 0.043933761 RSA1 -- ribosome biogenesis (putative) -- Nucleoplasmic assembly of 60S ribosomal subunits YPR134W MSS18 0.3 15 0.9 0.2366 0.745666147 iYPR133W-A YPR133W-A 0.434450283 0.664162039 0.747885076 0.400867214 0.454489867 "MSS18 -- mRNA splicing, COX1 mRNA -- splicing intron A15beta of COX1" YBR213W MET8 0.2 9 0.9 0.2366 0.133919553 iYBR212W 0.477254331 0.428006776 0.446261682 "MET8 -- sulfate assimilation -- S-adenosyl-L-methionine uroporphyrinogen III dehydrogenase and chelatase required for siroheme production, involved in the expression of PAPS reductase and sulfite reductase" YGL065C ALG2 0.2 11 0.9 0.2366 0.845325187 iYGL065C 0.206248559 0.897446129 0.231205108 "ALG2 -- protein glycosylation -- Mannosyltransferase involved in N-glycosylation, converts Man[2]GlcNAc-PP-Dolichol to Man[3]GlcNAc-PP-Dolichol" YHL006C YHL006C 0.2 11 0.9 0.2366 0.163986297 0.651559454 YHL006C -- unknown -- unknown function YIL061C SNP1 0.2 10 0.9 0.2366 0.237355322 iYIL061C YILCdelta2 0.299517206 0.815455735 0.254467186 0.039026337 0.941347083 "SNP1 -- mRNA splicing -- U1 snRNA-associated RNA recognition (RRM) domain, homologous to human 70 kDa U1 snRNP protein" YJL019W YJL019W 0.2 11 0.9 0.2366 0.342970754 iYJL020C 0.471372505 0.527853205 0.470562544 "YJL019W -- unknown -- unknown function, overlaps with YJL019W" YJR078W YJR078W 0.2 10 0.9 0.2366 0.201439852 iYJR077C 0.212610549 0.612391234 0.358040606 "YJR078W -- unknown -- similarity to indoleamine 2,3-dioxygenases, which catalyze conversion of tryptophan and other indole derivatives into kynurenines" YKL111C YKL111C 0.2 11 0.9 0.2366 0.37111671 iYKL111C 0.762829853 0.621011924 0.660181962 YKL111C -- unknown -- unknown functionquestionable ORF YNL187W YNL187W 0.2 12 0.9 0.2366 0.477703365 iYNL188W 0.418077124 0.897845172 0.400016113 YNL187W -- unknown -- unknown function YNL334C SNO2 0.2 11 0.9 0.2366 iYNL334C 0.489033723 0.192051345 "SNO2 -- unknown -- Putative pyridoxine (vitamin B6) biosynthetic enzyme with similarity to glutamine aminotransferases, has strong similarity to Sno1p and Sno3p" YIL139C REV7 0.1 7 0.9 0.2366 0.32139185 iYIL139C 0.531273692 0.580947003 0.3429987 "REV7 -- DNA repair -- DNA polymerase zeta, small subunit, required for mutagenesis by physical and chemical agents" YKL151C YKL151C 1 48 0.8 0.2026 1 0.945973065 iYKL151C 0.893278506 0.808628938 0.363860775 YKL151C -- unknown -- unknown function YOL082W YOL082W 0.4 19 0.8 0.2026 1 0.942440834 iYOL083W-0 iYOL083W-1 0.944309535 0.990099477 0.627009085 0.794549266 0.783788174 YOL082W -- unknown -- unknown function YNL253W YNL253W 0.3 14 0.8 0.2026 1 0.915027189 iYNL254C 0.959562311 0.874006441 0.669432807 YNL253W -- unknown -- unknown function YPL162C YPL162C 0.2 13 0.8 0.2026 1 0.979287923 iYPL162C 0.972644233 0.337638077 0.027909978 "YPL162C -- unknown -- unknown function, putative membrane protein" YBL064C YBL064C 1.9 85 0.8 0.2026 0.487790268 iYBL064C 0.434917698 0.861457817 0.542147294 YBL064C -- unknown -- Mitochondrial thiol peroxidase YLR194C YLR194C 1.9 90 0.8 0.2026 0.133679868 iYLR194C 0.607804012 0.207924975 0.587948923 YLR194C -- unknown -- unknown function YOR059C YOR059C 1 49 0.8 0.2026 0.51723293 iYOR059C 0.148110085 0.835526316 0.203754431 YOR059C -- unknown -- unknown function YCR042C TSM1 0.9 42 0.8 0.2026 0.539136124 iYCR042C 0.34663692 0.162889066 0.634831008 TSM1 -- transcription -- Component of TAF(II) complex (TBP-associated protein complex)required for activated transcription by RNA polymerase II YCR093W CDC39 0.9 38 0.8 0.2026 0.400346875 iYCR092C 0.11949804 0.306692948 0.026118099 CDC39 -- transcription -- Nuclear negatively affects basal transcription from many promoters YLL051C FRE6 0.9 44 0.8 0.2026 0.802335028 iYLL051C 0.857386222 0.774221868 0.312378168 "FRE6 -- unknown -- similarity to ferric reductase Fre2p, subject to regulation by iron" YLR346C YLR346C 0.9 42 0.8 0.2026 0.693239101 iYLR346C 0.862673717 0.712858524 0.942486085 YLR346C -- unknown -- unknown function YPL184C YPL184C 0.9 38 0.8 0.2026 0.316450542 iYPL184C YPL183W-A 0.237706787 0.234561198 0.496507472 0.051413255 0.055994199 YPL184C -- unknown -- unknown function YDL193W YDL193W 0.8 34 0.8 0.2026 0.362209444 iYDL194W 0.367108937 0.617649431 0.795160727 YDL193W -- unknown -- associated with lipid particles YGL036W MTC2 0.8 35 0.8 0.2026 0.321866519 iYGL037C 0.344123974 0.659343372 0.095929769 MTC2 -- unknown -- unknown function YGR207C ETF-BETA 0.8 37 0.8 0.2026 0.194241351 iYGR207C 0.441993902 0.50103751 0.526564347 "ETF-BETA -- unknown -- Electron-transferring flavoprotein, beta chain" YIL101C XBP1 0.8 35 0.8 0.2026 0.180670201 iYIL101C 0.468158769 0.144655641 0.034796488 XBP1 -- stress response -- Stress-induced transcriptional repressor YIL108W YIL108W 0.8 37 0.8 0.2026 0.327489908 iYIL109C 0.509956289 0.640461216 0.519585702 YIL108W -- unknown -- motif characteristic of zinc metallopeptidase zinc-binding proteins YLR251W YLR251W 0.8 35 0.8 0.2026 0.710388762 iYLR250W 0.159877464 0.604501089 0.47321649 YLR251W -- unknown -- similarity to mouse MPV17 protein YML091C RPM2 0.8 33 0.8 0.2026 0.509696806 0.267000081 "RPM2 -- tRNA processing, mitochondrial -- component of Ribonuclease P (RNase P) of mitochondria, generates mature tRNA molecules by cleaving their 5' ends" YOR208W PTP2 0.8 37 0.8 0.2026 0.235113246 iYOR207C 0.017275553 0.371942697 0.010220126 "PTP2 -- signaling, high osmolarity pathway -- Protein tyrosine phosphatase (PTPase), involved in Hog1p MAP kinase high-osmolarity sensing pathway and Fus3p MAP kinase pheromone response pathway" YAL015C NTG1 0.7 31 0.8 0.2026 0.30955874 iYAL015C 0.225588504 0.542966212 0.147616359 NTG1 -- DNA repair -- 8-oxoguanine YDR074W TPS2 0.7 28 0.8 0.2026 0.681266441 iYDR073W 0.354068972 0.82605543 0.479385045 "TPS2 -- trehalose metabolism -- Trehalose-6-phosphate phosphatase, component of trehalose-6-phosphatase synthase/phosphatase complex" YGL193C YGL193C 0.7 34 0.8 0.2026 0.664280999 0.936233041 YGL193C -- unknown -- unknown function YGR184C UBR1 0.7 30 0.8 0.2026 0.538086907 iYGR184C 0.432690422 0.464797345 0.290981644 "UBR1 -- protein degradation, ubiquitin-mediated -- Ubiquitin-protein ligase (N-recognin or E3 enzyme), involved in selection of substrates for the N-end rule pathway" YLR189C UGT51 0.7 32 0.8 0.2026 0.335156787 iYLR189C 0.30959276 0.48689199 0.58839972 UGT51 -- sterol metabolism -- Sterol glucosyltransferase (UDP-glucose YLR356W YLR356W 0.7 29 0.8 0.2026 0.231460624 iYLR355C 0.52481834 0.431444533 0.828230744 "YLR356W -- unknown -- similarity to Scm4p, possible Cdc4p-interacting protein" YML057W CMP2 0.7 33 0.8 0.2026 0.379876963 0.519792498 "CMP2 -- signaling -- Calcineurin catalytic (A) subunit, protein serine/threonine phosphatase 2B (PP2B), member of PPP family of protein phosphatases" YBR183W YPC1 0.6 26 0.8 0.2026 0.886935218 iYBR182C 0.592805753 0.973663208 0.8111505 YPC1 -- sphingolipid metabolism -- Alkaline ceramidase YDR054C CDC34 0.6 26 0.8 0.2026 0.154140439 iYDR054C 0.761858507 0.230263158 0.928906443 "CDC34 -- protein degradation, ubiquitin-mediated -- Ubiquitin-conjugating enzyme (E2)component of SCF (Skp1p-Cdc53p-F-box) complexes which act with various F-box proteins to direct target proteins into the ubiquitin-dependent degradation pathway" YDR490C PKH1 0.6 26 0.8 0.2026 0.376935814 iYDR490C 0.173395385 0.550518755 0.250837989 "PKH1 -- unknown -- Serine/threonine protein kinase, functions similarly to mammalian 3-phosphoinositide-dependent protein kinasephosphorylates and activates Ypk1p" YGL140C YGL140C 0.6 26 0.8 0.2026 0.378116378 iYGL140C 0.545811635 0.559696728 0.261612131 YGL140C -- unknown -- unknown function YGL223C YGL223C 0.6 26 0.8 0.2026 0.256192326 iYGL223C 0.19788878 0.514193984 0.162283349 YGL223C -- unknown -- unknown function YGL237C HAP2 0.6 26 0.8 0.2026 0.407156296 iYGL237C 0.261735051 0.749197729 0.282043097 "HAP2 -- transcription; respiration -- Component (with Hap3p, Hap4p, and Hap5p) of heterotrimeric CCAAT-binding factor, has a highly conserved core region of 60 amino acids that possess all the essential functions" YIL169C YIL169C 0.6 27 0.8 0.2026 0.56935912 iYIL169C-0 iYIL169C-1 0.819254512 0.767069585 0.424045286 0.759668063 0.597491958 YIL169C -- unknown -- unknown function YIR043C 0.6 25 0.8 0.2026 0.863563905 iYIR043C 0.74946005 0.366056304 0.31177487 YJL057C IKS1 0.6 28 0.8 0.2026 0.102744201 iYJL057C 0.154374116 0.580244924 0.036923435 IKS1 -- signaling (putative) -- Probable serine/threonine protein kinase YJL199C YJL199C 0.6 28 0.8 0.2026 0.120240318 iYJL199C 0.144337803 0.227877712 0.105347167 YJL199C -- unknown -- unknown function YLR190W YLR190W 0.6 26 0.8 0.2026 0.295104477 iYLR189C 0.30959276 0.644672098 0.58839972 YLR190W -- unknown -- unknown function YLR240W VPS34 0.6 24 0.8 0.2026 0.240273173 iYLR239C 0.409548472 0.455328135 0.395498911 "VPS34 -- vacuolar protein targeting -- Phosphatidylinositol 3-kinase (PI 3-kinase) required for vacuolar protein sorting, activated by protein kinase Vps15p" YLR410W VIP1 0.6 24 0.8 0.2026 0.531612858 iYLR409C 0.672771617 0.556505606 0.545136284 VIP1 -- unknown -- possible methionine N(alpha)-acetyltransferase activityinvolved in cortical actin function YMR124W YMR124W 0.6 25 0.8 0.2026 iYMR123W 0.480929806 0.553471668 "YMR124W -- unknown -- unknown function, has potential coiled-coil region" YMR136W GAT2 0.6 26 0.8 0.2026 0.402122357 iYMR135W-A 0.065403918 0.388539483 0.321102458 GAT2 -- transcription (putative) -- GATA zinc finger transcription factor YMR258C YMR258C 0.6 27 0.8 0.2026 0.570117932 iYMR258C 0.776681886 0.918914605 0.689602323 YMR258C -- unknown -- unknown function YNL115C YNL115C 0.6 28 0.8 0.2026 0.1184991 iYNL115C 0.217363746 0.332428207 0.380956404 YNL115C -- unknown -- unknown function YNL159C YNL159C 0.6 25 0.8 0.2026 0.347357322 iYNL159C 0.202857208 0.35351153 0.278820305 YNL159C -- unknown -- unknown function YOR080W YOR080W 0.6 26 0.8 0.2026 0.129692544 iYOR079C 0.536180201 0.409006421 0.507258803 "YOR080W -- unknown -- unknown function, contains an F-box, tetratricopeptide (TPR) repeats and leucine-rich (LRR) repeats" YOR290C SNF2 0.6 24 0.8 0.2026 0.296416176 iYOR290C 0.555173707 0.092652272 0.17168954 "SNF2 -- transcription -- Component of SWI-SNF global transcription activator complex, acts to assist gene-specific activators through chromatin remodeling" YPL055C YPL055C 0.6 26 0.8 0.2026 0.024147585 iYPL055C 0.265548855 0.069688109 0.129433062 YPL055C -- unknown -- unknown function YAL031C YAL031C 0.4 23 0.8 0.2026 0.754632795 iYAL031C 0.382883171 0.558652917 0.284277733 YAL031C -- unknown -- unknown function YBR013C YBR013C 0.4 21 0.8 0.2026 0.732740315 iYBR013C iYBRCdelta14 0.491637853 0.622058722 0.898824932 0.621707901 0.648082501 YBR013C -- unknown -- unknown function YBR060C ORC2 0.4 21 0.8 0.2026 0.826118472 iYBR060C-0 iYBR060C-1 0.912706681 0.698149066 0.591202063 0.641526475 0.636180992 "ORC2 -- DNA replication -- Origin recognition complex, 72 kDa subunit, functions early in DNA replication" YBR215W HPC2 0.4 18 0.8 0.2026 0.025143544 iYBR214W 0.255325991 0.036862334 0.541663306 HPC2 -- transcription -- regulation of histone gene transcription throughout the cell cycle YBR227C MCX1 0.4 20 0.8 0.2026 0.354862336 iYBR227C 0.120427687 0.528301887 0.031813404 MCX1 -- protein folding -- similarity to E. coli ATP-binding protein clpX YCL042W YCL042W 0.4 24 0.8 0.2026 0.229454827 0.181963288 YCL042W -- unknown -- unknown function YCR019W MAK32 0.4 19 0.8 0.2026 0.276928167 iYCR018C-A 0.267121435 0.220754109 0.534591195 MAK32 -- dsRNA virus propagation -- structural stability of L-A double-stranded RNA- (dsRNA-) containing particles YDL045C FAD1 0.4 23 0.8 0.2026 0.340014984 iYDL045C 0.292420386 0.571140831 0.153264771 FAD1 -- flavin biosynthesis -- Flavin adenine dinucleotide (FAD) synthetasesecond step in synthesis of FAD from riboflavin YDR080W VPS41 0.4 20 0.8 0.2026 0.30836322 iYDR079W 0.353218336 0.275339186 0.684117125 "VPS41 -- vacuolar protein targeting -- formation of AP-3 transport vesicles, involved in the last step of vacuolar assembly" YDR204W COQ4 0.4 20 0.8 0.2026 0.475873521 iYDR203W 0.502419854 0.906208356 0.629304743 COQ4 -- ubiquinone biosynthesis -- biosynthesis of coenzyme Q YDR288W YDR288W 0.4 22 0.8 0.2026 0.390777407 iYDR287W 0.255581716 0.903963906 0.242720013 YDR288W -- unknown -- unknown function YDR420W HKR1 0.4 19 0.8 0.2026 0.395802347 iYDR419W itS(AGA)D3 0.697829854 0.449595108 0.284643893 0.681963288 0.493056664 HKR1 -- cell wall biogenesis (putative) -- Hansenula mrakii K9 killer toxin-resistance protein YDR520C YDR520C 0.4 20 0.8 0.2026 0.510110873 0.894094174 "YDR520C -- unknown -- similarity to glycosyl hydrolase, contains a Zn[2]-Cys[6] fungal-type binuclear cluster domain" YFL008W SMC1 0.4 20 0.8 0.2026 0.46160693 iYFL009W 0.354367549 0.532232704 0.232115091 "SMC1 -- mitosis, chromosome condensation and segregation -- Coiled-coil SMC family involved in chromosome condensation and segregation" YGL093W SPC105 0.4 20 0.8 0.2026 0.325590434 iYGL094C 0.42421502 0.51660016 0.552585604 SPC105 -- cytoskeleton -- spindle pole body YGR202C PCT1 0.4 18 0.8 0.2026 0.518297656 iYGR202C 0.71424276 0.593404808 0.771825887 PCT1 -- phospholipid metabolism -- Cholinephosphate cytidylyltransferase YIL013C PDR11 0.4 22 0.8 0.2026 0.596343581 iYIL013C 0.225661549 0.337576539 0.175555914 PDR11 -- transport -- membrane transporter of ATP-binding cassette (ABC) superfamily YIL112W YIL112W 0.4 19 0.8 0.2026 0.268918917 iYIL113W 0.435486482 0.367400419 0.610698245 YIL112W -- unknown -- similarity to ankyrin and coiled-coil proteins YIL170W 0.4 18 0.8 0.2026 0.518952425 0.813567438 YJL142C YJL142C 0.4 21 0.8 0.2026 0.608556965 0.595490825 YJL142C -- unknown -- unknown function YJL165C HAL5 0.4 20 0.8 0.2026 0.494201626 iYJL165C 0.339950245 0.733161457 0.572386273 HAL5 -- salt tolerance -- Serine/threonine protein kinase involved in salt and pH tolerance YJL194W CDC6 0.4 20 0.8 0.2026 0.773035295 0.82863358 "CDC6 -- DNA replication -- regulates initiation of DNA replication, binds to origins of replication at the end of mitosis, directing the assembly of MCM proteins and the pre-replication complex, member of AAA+ family of ATPases" YKL089W MIF2 0.4 20 0.8 0.2026 0.182723697 iYKL090W 0.617564563 0.427891958 0.320480761 MIF2 -- mitosis -- Centromere normal chromosome segregation and spindle integrity YLR007W YLR007W 0.4 22 0.8 0.2026 0.503874103 iYLR006C 0.247932351 0.894054141 0.283000798 YLR007W -- unknown -- unknown function YLR182W SWI6 0.4 21 0.8 0.2026 0.522227731 iYLR181C 0.109816559 0.322612086 0.083000798 SWI6 -- cell cycle -- Transcription factor that participates in the SBF complex (Swi4p-Swi6p) for regulation at the cell cycle box (CCB) and in the MBF complex (Mbp1p-Swi6p) for regulation at the Mlu1 cell cycle box (MCB) YLR242C ARV1 0.4 18 0.8 0.2026 0.777147756 iYLR242C 0.182361815 0.817759378 0.167627533 ARV1 -- unknown -- viability in are1 and are2 null mutants YML112W CTK3 0.4 18 0.8 0.2026 0.061230833 iYML113W 0.683068227 0.0805718 0.565383366 "CTK3 -- cell cycle (putative) -- C-terminal domain (RNA polymerase II CTD) kinase gamma subunit, associates with Ctk1p and Ctk2p" YMR087W YMR087W 0.4 20 0.8 0.2026 0.829079544 iYMR086C-A 0.875446284 0.414445331 0.068555467 YMR087W -- unknown -- unknown function YMR115W YMR115W 0.4 23 0.8 0.2026 0.563904014 iYMR114C 0.605783542 0.670869912 0.476324917 YMR115W -- unknown -- unknown function YMR173W DDR48 0.4 22 0.8 0.2026 0.130256947 iYMR172C-A 0.266441126 0.455755425 0.158739026 "DDR48 -- unknown -- Stress protein induced by heat shock, DNA damage, or osmotic stress" YMR257C PET111 0.4 21 0.8 0.2026 0.36654688 iYMR257C 0.32639204 0.626140588 0.637545976 PET111 -- protein synthesis -- mitochondrial translation of COX2 mRNA YNR014W YNR014W 0.4 19 0.8 0.2026 0.07097586 iYNR013C 0.022490934 0.265225458 0.017300195 YNR014W -- unknown -- unknown function YNR019W ARE2 0.4 19 0.8 0.2026 0.240137097 iYNR018W 0.203572098 0.394249513 0.104979053 ARE2 -- sterol metabolism -- Acyl-CoA YOL045W YOL045W 0.4 19 0.8 0.2026 0.301432555 0.14668616 YOL045W -- unknown -- Serine/threonine protein kinase of unknown function YOL072W YOL072W 0.4 24 0.8 0.2026 0.263073044 iYOL073C 0.478675445 0.528134505 0.083548179 YOL072W -- unknown -- unknown function YOL075C YOL075C 0.4 21 0.8 0.2026 0.2856174 iYOL075C 0.356137953 0.674788824 0.384760964 "YOL075C -- unknown -- Member of ATP-binding cassette (ABC) superfamily, with similarity to Drosophila white protein and Anopheles gambiae ABC protein" YOL165C AAD15 0.4 19 0.8 0.2026 0.939598293 iYOL165C iYOLCdelta1 0.90083039 0.794024345 0.628252195 0.890941357 0.36996455 "AAD15 -- unknown -- Putative aryl alcohol dehydrogenase, may participate in late steps of degradation of aromatic compounds that arise from the degradation of lignocellulose" YOR053W YOR053W 0.4 20 0.8 0.2026 0.06809229 iYOR052C 0.068335174 0.060162706 0.029175402 YOR053W -- unknown -- similarity to protamines YOR225W YOR225W 0.4 18 0.8 0.2026 0.32917212 iYOR224C 0.037623873 0.589709993 0.008612078 YOR225W -- unknown -- unknown function YOR377W ATF1 0.4 22 0.8 0.2026 0.688651769 iYOR376W-0 iYOR376W-1 0.312693644 0.293507654 0.321149242 0.152416357 0.548823719 ATF1 -- acetate ester biosynthesis -- Alcohol acetyltransferasereacts with acetyl-CoA and various alcohols to produce acetate esters YPL107W YPL107W 0.4 21 0.8 0.2026 0.008198365 0.015199161 YPL107W -- unknown -- unknown function YPL167C REV3 0.4 18 0.8 0.2026 0.610525373 iYPL167C 0.823782569 0.358635154 0.878842264 "REV3 -- DNA repair -- DNA polymerase zeta, involved in mutagenic translesion DNA repair synthesis" YPR107C YTH1 0.4 20 0.8 0.2026 0.733192919 iYPR107C 0.174933676 0.658260176 0.247157245 YTH1 -- mRNA 3'-end processing -- Component of polyadenylation factor I YAR044W OSH1 0.3 17 0.8 0.2026 0.447884813 iYAR042W 0.01681482 0.289148798 0.026828875 "OSH1 -- sterol biosynthesis (putative) -- implicated in ergosterol biosynthesis, member of KES1/HES1/OSH1/YKR003W family of oxysterol-binding (OSBP) proteins" YBL043W ECM13 0.3 17 0.8 0.2026 0.228354033 iYBL044W 0.347778004 0.603582291 0.737707008 ECM13 -- cell wall biogenesis -- Protein possibly involved in cell wall structure or biosynthesis YBL071C YBL071C 0.3 15 0.8 0.2026 0.901137518 iYBL071C 0.920575462 0.633934373 0.323025856 "YBL071C -- unknown -- unknown function, has a peroxisomal targeting signal" YBR044C TCM62 0.3 18 0.8 0.2026 0.600081414 iYBR044C tV(UAC)B 0.702168283 0.552512583 0.853754941 0.733563729 0.339797345 TCM62 -- protein folding -- Chaperone-like the assembly of mitochondrial succinate dehydrogenase complex YBR094W YBR094W 0.3 17 0.8 0.2026 0.177114248 iYBR093C 0.464398798 0.652194733 0.545297457 YBR094W -- unknown -- unknown function YBR097W VPS15 0.3 17 0.8 0.2026 0.58923548 iYBR096W 0.637526307 0.577344505 0.591866651 VPS15 -- vacuolar protein targeting -- Serine/threonine protein kinase involved in vacuolar protein sorting YBR197C YBR197C 0.3 13 0.8 0.2026 0.807701584 iYBR197C 0.513271517 0.561127838 0.458431903 YBR197C -- unknown -- unknown function YBR292C YBR292C 0.3 15 0.8 0.2026 0.673944384 iYBR292C-0 iYBR292C-1 0.264057175 0.62939143 0.882686932 0.416103413 0.651949726 YBR292C -- unknown -- unknown function YDL017W CDC7 0.3 17 0.8 0.2026 0.327864419 iYDL018C 0.436640347 0.552673583 0.564804469 "CDC7 -- cell cycle -- kinase that acts in complex with Dbf4p to affect initiation of DNA synthesis, commitment to sporulation, DNA repair, and meiotic recombination" YDL044C MTF2 0.3 19 0.8 0.2026 0.495423524 iYDL044C 0.396685942 0.284181563 0.640235541 "MTF2 -- mRNA splicing, mitochondrial -- Mitochondrial mRNA splicing and protein synthesis, required for splicing of OXI3/COX1 mRNA" YDL105W QRI2 0.3 14 0.8 0.2026 0.424882629 iYDL106C 0.136247551 0.3207502 0.217472119 QRI2 -- unknown -- unknown function YDL156W YDL156W 0.3 14 0.8 0.2026 0.250768982 iYDL157C 0.222632287 0.491720176 0.537270551 YDL156W -- unknown -- unknown functionhas WD (WD-40) repeats YDL210W UGA4 0.3 17 0.8 0.2026 iYDL211C-0 iYDL211C-1 0.388588705 0.595982785 0.621331237 0.720562824 UGA4 -- transport -- Amino acid permease with high specificity for 4-aminobutyric acid (GABA) YDR066C YDR066C 0.3 16 0.8 0.2026 0.771954582 iYDR066C 0.271238608 0.95014923 0.337089448 YDR066C -- unknown -- unknown functionhas similarity to Yer139p YDR113C PDS1 0.3 15 0.8 0.2026 0.690419955 iYDR113C 0.44719217 0.433641975 0.178109713 PDS1 -- cell cycle -- regulates sister chromatid separation in mitosis YDR363W ESC2 0.3 18 0.8 0.2026 0.260142657 iYDR362C 0.473671517 0.606806368 0.424296201 ESC2 -- silencing -- chromatin silencing YDR444W YDR444W 0.3 17 0.8 0.2026 0.494047193 iYDR443C 0.499859176 0.403346329 0.673480084 "YDR444W -- unknown -- unknown function, has strong similarity to Ydl109p and Ygl144p" YER060W FCY21 0.3 17 0.8 0.2026 0.471192048 iYER059W 0.614092772 0.55782976 0.603883815 "FCY21 -- transport -- similarity to Fcy2p, member of purine/cytosine family of secondary active transporters" YFR016C YFR016C 0.3 16 0.8 0.2026 0.108665541 iYFR016C itG(GCC)F2 0.553504938 0.481239157 0.188347965 0.17807483 0.536692009 YFR016C -- unknown -- weak similarity to Uso1p and to rat neurofilament triplet M protein YGL168W YGL168W 0.3 19 0.8 0.2026 0.704544539 iYGL169W 0.763066164 0.95206252 0.396856743 YGL168W -- unknown -- unknown functionquestionable ORF YGL179C YGL179C 0.3 15 0.8 0.2026 0.665938321 iYGL179C-0 iYGL179C-1 0.413787312 0.644582171 0.969912211 0.850689683 0.441387142 YGL179C -- unknown -- Serine/threonine protein kinase with similarity to Elm1p and Kin82p YGL208W SIP2 0.3 14 0.8 0.2026 0.842158209 iYGL209W 0.226280825 0.610538189 0.073808936 "SIP2 -- transcription -- Dominant suppressor of some temperature-sensitive mutations in RPO21 and PRP4, interacts with Snf1p" YGR201C YGR201C 0.3 16 0.8 0.2026 0.235126347 iYGR201C 0.080447566 0.444516204 0.12802127 YGR201C -- unknown -- similarity to translation elongation factors YGR237C YGR237C 0.3 18 0.8 0.2026 0.320814715 iYGR237C 0.359460624 0.434129305 0.424416028 "YGR237C -- unknown -- unknown function, contains a UspA ATP-binding domain" YHR097C YHR097C 0.3 19.5 0.8 0.2026 0.939445488 iYHR097C 0.821300229 0.42652272 0.670565302 YHR097C -- unknown -- unknown function YHR150W YHR150W 0.3 14 0.8 0.2026 0.454635461 iYHR149C 0.231423021 0.878111409 0.406227313 YHR150W -- unknown -- unknown function YHR151C YHR151C 0.3 15 0.8 0.2026 0.634068311 iYHR151C 0.35514504 0.377672017 0.066926576 YHR151C -- unknown -- unknown function YHR178W STB5 0.3 14 0.8 0.2026 0.897162668 iYHR177W 0.328696268 0.93491319 0.292438081 STB5 -- transcription -- similarity to transcription factors YHR198C YHR198C 0.3 13 0.8 0.2026 0.282493891 iYHR198C 0.595828456 0.399078417 0.464905785 YHR198C -- unknown -- similarity to Yhr199p YIL119C RPI1 0.3 15 0.8 0.2026 0.410560977 iYIL119C-0 iYIL119C-1 0.40958394 0.248512242 0.716806429 0.324968507 0.586835525 "RPI1 -- signaling, Ras pathway -- Negative regulator of ras-cAMP pathway, downregulates normal but not mutant ras function" YJL017W YJL017W 0.3 15 0.8 0.2026 0.246406403 iYJL018W 0.28525174 0.524923961 0.14179826 YJL017W -- unknown -- unknown function YJL113W 0.3 17 0.8 0.2026 0.840160733 0.901655965 YJL118W YJL118W 0.3 18 0.8 0.2026 0.219078424 0.448424301 YJL118W -- unknown -- unknown function YJL203W PRP21 0.3 15 0.8 0.2026 0.142374789 iYJL204C 0.284385045 0.370108316 0.442332684 "PRP21 -- mRNA splicing -- Pre-mRNA splicing factor (snRNA-associated protein), required for the addition of U2 snRNA to prespliceosomes" YJL204C 0.3 17 0.8 0.2026 0.573349714 iYJL204C 0.284385045 0.707634521 0.442332684 YJR040W GEF1 0.3 16 0.8 0.2026 0.523170309 iYJR039W 0.378356478 0.898646471 0.458898643 "GEF1 -- transport -- Voltage-gated chloride channel, has effects on intracellular iron metabolism" YJR083C YJR083C 0.3 15 0.8 0.2026 0.243693686 iYJR083C 0.350194734 0.498951782 0.070143256 YJR083C -- unknown -- unknown function YJR093C FIP1 0.3 16 0.8 0.2026 0.459994532 iYJR093C 0.600173546 0.404527876 0.423681396 FIP1 -- mRNA polyadenylation -- Component of polyadenylation factor that interacts with poly(A) polymerase YKL061W YKL061W 0.3 16 0.8 0.2026 0.397616168 iYKL062W 0.16114015 0.188674679 0.234707672 YKL061W -- unknown -- unknown function YKL198C PTK1 0.3 14 0.8 0.2026 0.521760619 iYKL198C 0.02892084 0.462616822 0.20230608 "PTK1 -- polyamine transport -- Serine/threonine protein kinase, activator of low-affinity, low-capacity polyamine transport" YKL217W JEN1 0.3 16 0.8 0.2026 0.42279957 iYKL218C-0 iYKL218C-1 0.30195945 0.142013031 0.763733161 0.259433962 0.428671088 "JEN1 -- transport -- Lactate-proton symporter, member of major facilitator superfamily (MFS)" YKR106W YKR106W 0.3 14 0.8 0.2026 0.948501783 iYKR105C 0.939092153 0.589107316 0.323623797 YKR106W -- unknown -- Member of yeast-specific putative multidrug-resistance family of major facilitator superfamily (MFS) YLR032W RAD5 0.3 17 0.8 0.2026 0.500713407 iYLR031W 0.343920874 0.495770152 0.118099231 "RAD5 -- DNA repair -- DNA helicase of Snf2p family and member of RAD6 epistasis group, involved in error-free DNA repair" YLR227C YLR227C 0.3 17 0.8 0.2026 0.247741031 iYLR227C itL(UAG)L1 0.575732059 0.44653386 0.503330084 0.543404921 0.444406894 YLR227C -- unknown -- unknown function YLR464W YLR464W 0.3 14 0.8 0.2026 0.951584637 0.886352753 YLR464W -- unknown -- similarity to other subtelomerically-coded proteins YML109W ZDS2 0.3 17 0.8 0.2026 0.202550617 iYML110C 0.591982517 0.584547025 0.607082359 "ZDS2 -- cell cycle -- regulation of transcriptional silencing and life span, multicopy suppressor of sin4" YMR066W SOV1 0.3 16 0.8 0.2026 0.260127409 iYMR065W 0.74959417 0.605027933 0.811670161 SOV1 -- respiration (putative) -- unknown function YMR291W YMR291W 0.3 16 0.8 0.2026 0.293241788 iYMR290W-A 0.436850668 0.593369364 0.215643275 YMR291W -- unknown -- Serine/threonine protein kinase of unknown function YNL073W MSK1 0.3 15 0.8 0.2026 0.458329351 iYNL074C 0.203847769 0.575139147 0.27442089 "MSK1 -- protein synthesis -- Lysyl-tRNA synthetase, mitochondrial" YNL082W PMS1 0.3 13 0.8 0.2026 0.399851264 iYNL083W 0.384104072 0.809378021 0.356568833 "PMS1 -- DNA repair -- mismatch repair, homologous to E. coli MutL" YNL245C YNL245C 0.3 14 0.8 0.2026 0.195078994 iYNL245C 0.266416204 0.249918778 0.383934373 YNL245C -- unknown -- unknown function YNR032W PPG1 0.3 17 0.8 0.2026 0.195466089 iYNR031C 0.054371178 0.604048383 0.143180861 "PPG1 -- glycogen metabolism -- Protein serine/threonine phosphatase involved in glycogen accumulation, member of PPP family of protein phosphatases and related to PP2A phosphatases" YNR051C YNR051C 0.3 17 0.8 0.2026 0.172541985 iYNR051C 0.409041877 0.086529165 0.772625698 YNR051C -- unknown -- n an RNA recognition (RRM) domain YOL135C MED7 0.3 14 0.8 0.2026 0.930154397 iYOL135C 0.670281727 0.178319664 0.159931872 MED7 -- transcription -- Component of RNA polymerase II holoenzyme and mediator subcomplex YOR110W TFC7 0.3 14 0.8 0.2026 0.372003429 iYOR109W 0.771607192 0.484611666 0.545958632 "TFC7 -- unknown -- RNA Polymerase III transcription initiation factor TFIIIC (tau), 55 kDa subunit" YOR126C IAH1 0.3 17 0.8 0.2026 0.811842843 iYOR126C 0.592634434 0.607718337 0.510918938 IAH1 -- unknown -- Isoamyl acetate-hydrolyzing esterase enzyme YOR249C APC5 0.3 15 0.8 0.2026 0.263204764 iYOR249C 0.432127046 0.48622301 0.454949395 "APC5 -- mitosis -- Component of anaphase-promoting complex (APC), required for Clb2p degradation and for the metaphase-anaphase transition" YOR371C YOR371C 0.3 17 0.8 0.2026 0.45698658 iYOR371C 0.253906191 0.297571993 0.220351157 YOR371C -- unknown -- unknown function YPL140C MKK2 0.3 18 0.8 0.2026 0.500312962 iYPL140C 0.379150767 0.754134782 0.437718379 "MKK2 -- signaling, PKC1 pathway -- MAP kinase kinase (MEK) serine/threonine protein kinaseinvolved in cell wall integrity (low-osmolarity) pathway" YPL253C VIK1 0.3 15 0.8 0.2026 0.114509447 iYPL253C 0.003966287 0.09365169 0.001687989 VIK1 -- nuclear fusion (putative) -- Probable coiled-coil interacts with Kar3p YPR091C YPR091C 0.3 18 0.8 0.2026 0.304721588 0.246687949 YPR091C -- unknown -- unknown function YPR141C KAR3 0.3 15 0.8 0.2026 0.06007622 iYPR141C 0.498187737 0.079489226 0.538228252 "KAR3 -- mating; nuclear fusion; mitosis -- Kinesin-like mitosis and essential for the congression (nuclear migration) step of karyogamy, probable coiled-coil protein" YPR155C NCA2 0.3 16 0.8 0.2026 0.290803335 iYPR155C 0.514178976 0.637928022 0.552771511 NCA2 -- ATP synthesis -- control of mitochondrial synthesis of Atp6p and Atp8p YDR453C YDR453C 0.2 12 0.8 0.2026 0.686418969 iYDR453C 0.613802532 0.929687275 0.829260265 YDR453C -- unknown -- Cytoplasmic thiol peroxidase YER180C ISC10 0.2 13 0.8 0.2026 0.863551873 iYER180C itI(AAU)E2 0.291302374 0.51390511 0.984036863 0.237833728 0.293538759 "ISC10 -- meiosis, spore formation -- Meiosis-specific spore formation" YFR029W PTR3 0.2 12 0.8 0.2026 0.412674052 iYFR028C itY(GUA)F2 0.489935441 0.769258233 0.349983887 0.197124756 0.475786735 PTR3 -- transport -- Peptide permease regulator YGR091W PRP31 0.2 10 0.8 0.2026 0.780844488 iYGR090W 0.775849393 0.787624879 0.580427893 "PRP31 -- mRNA splicing -- pre-mRNA splicing, associated with U4/U6.U5 tri-snRNP" YHR022C YHR022C 0.2 10 0.8 0.2026 0.968148306 iYHR022C 0.751141545 0.988507582 0.798644498 YHR022C -- unknown -- weak similarity to N-terminal region of ras-related proteins YIL003W YIL003W 0.2 12 0.8 0.2026 0.777088508 iYIL004C 0.54978259 0.9798745 0.729938769 "YIL003W -- unknown -- Essential unknown function, member of nucleotide binding protein family" YJL162C YJL162C 0.2 12 0.8 0.2026 0.252988462 iYJL162C itE(UUC)J 0.573567427 0.390702899 0.264179826 0.618790132 0.407145353 YJL162C -- unknown -- similarity to E. coli DnaJ and other DnaJ-like proteins YJL214W HXT8 0.2 12 0.8 0.2026 0.07154916 iYJL215C 0.694107172 0.165565582 0.394516931 HXT8 -- transport -- Member of hexose transporter family of major facilitator superfamily (MFS) YJR047C ANB1 0.2 12 0.8 0.2026 0.948184999 iYJR047C 0.66482383 0.983240223 0.180127694 "ANB1 -- protein synthesis -- Translation initiation factor eIF5A, contains essential hypusine modification" YJR154W YJR154W 0.2 12 0.8 0.2026 0.511431837 iYJR153W-0 iYJR153W-1 0.265275742 0.237743324 0.63632042 0.539657582 0.58170746 YJR154W -- unknown -- unknown function YLR139C SLS1 0.2 12 0.8 0.2026 0.146274425 0.107557203 SLS1 -- mitochondrial metabolism -- mitochondrial metabolism YLR349W YLR349W 0.2 13 0.8 0.2026 0.521290357 0.74382716 YLR349W -- unknown -- unknown function YNL054W VAC7 0.2 13 0.8 0.2026 0.09987564 iYNLWdelta4 0.371775191 0.062649641 0.67910087 "VAC7 -- vacuole biogenesis -- Integral vacuolar membrane protein, involved in vacuole morphology and inheritance" YNL279W YNL279W 0.2 11 0.8 0.2026 0.194051786 iYNL280C 0.156579657 0.496707114 0.485601355 YNL279W -- unknown -- unknown function YPL040C ISM1 0.2 11 0.8 0.2026 0.296505376 iYPL040C 0.281074117 0.481469546 0.220439398 "ISM1 -- protein synthesis -- Isoleucyl-tRNA synthetase, mitochondrial" YPL233W YPL233W 0.2 13 0.8 0.2026 0.166758448 iYPL234C 0.602804772 0.454759584 0.759696728 YPL233W -- unknown -- unknown function YPL241C CIN2 0.2 10 0.8 0.2026 0.847286163 iYPL241C 0.290633912 0.889245454 0.469062198 "CIN2 -- mitosis, chromosome segregation -- chromosome segregation" YPR068C HOS1 0.2 9 0.8 0.2026 0.637102148 iYPR068C 0.614278632 0.445430346 0.575657809 "HOS1 -- unknown -- similarity to Hda1p, Rpd3p, Hos2p, and Hos3p" YLR112W YLR112W 0.4 23 0.7 0.1682 1 0.971742846 iYLR111W 0.876157816 0.762180552 0.182866823 YLR112W -- unknown -- unknown function YPR106W ISR1 0.4 26 0.7 0.1682 1 0.93640857 iYPR105C 0.93163198 0.872146487 0.500760392 ISR1 -- staurosporine resistance -- Serine-threonine protein kinase involved in staurosporine resistance YMR265C YMR265C 0.3 18 0.7 0.1682 1 0.681149951 iYMR265C 0.927593903 0.534241789 0.688798495 YMR265C -- unknown -- unknown function YLR414C YLR414C 1.1 65 0.7 0.1682 0.783046443 iYLR414C 0.587395947 0.74022875 0.35748219 YLR414C -- unknown -- unknown function YDR262W 1 48 0.7 0.1682 0.802765516 YDRWsigma4 itG(GCC)D2 0.441312844 0.64147678 0.875578611 0.285818713 0.507542147 YOL081W IRA2 0.9 47 0.7 0.1682 0.413331659 iYOL082W 0.472687801 0.406464485 0.128736192 "IRA2 -- signaling, Ras pathway -- GTPase-activating protein for Ras1p and Ras2p" YBL051C YBL051C 0.8 40 0.7 0.1682 0.23628205 iYBL051C 0.258890752 0.444252448 0.189406969 "YBL051C -- unknown -- weak similarity to RNA-binding proteins, contains 1 RNA recognition (RRM) domain" YEL012W UBC8 0.8 40 0.7 0.1682 0.178645103 iYEL013W itQ(UUG)E2 0.448787392 0.489252586 0.410331384 0.495184184 0.734892788 "UBC8 -- protein degradation, ubiquitin-mediated -- Ubiquitin-conjugating enzyme involved in the catabolite degradation of fructose-1,6-bisphosphate" YDR143C SAN1 0.7 32 0.7 0.1682 0.172701887 iYDR143C 0.651214675 0.362310667 0.775378666 SAN1 -- silencing -- may antagonize the function of Spt16p and Sir4p YKL123W YKL123W 0.7 37 0.7 0.1682 0.450779767 0.626038558 YKL123W -- unknown -- unknown functionquestionable ORF YKR075C YKR075C 0.7 35 0.7 0.1682 0.335646152 iYKR075C-0 iYKR075C-1 0.076094728 0.275180986 0.617305833 0.075894296 0.344964515 YKR075C -- unknown -- similarity to Reg1p YOR127W RGA1 0.7 32 0.7 0.1682 0.301313833 iYOR126C 0.592634434 0.30011371 0.510918938 RGA1 -- bud site selection -- Rho-type GTPase-activating protein (GAP) for Cdc42p YOR132W VPS17 0.7 31 0.7 0.1682 0.263541377 iYOR131C 0.233918894 0.63506953 0.170626843 VPS17 -- vacuolar protein targeting -- Peripheral membrane vacuolar protein sortingmutant displays fragmented vacuoles YOR307C SLY41 0.7 33 0.7 0.1682 0.727458347 iYOR307C 0.338490157 0.792412977 0.329515205 "SLY41 -- secretion -- Member of triose phosphate translocator family of membrane transporters, indirectly involved in the secretory pathway" YBR071W YBR071W 0.6 34 0.7 0.1682 0.113585811 iYBR070C 0.264988322 0.289133473 0.193272566 YBR071W -- unknown -- weak similarity to Herpesvirus saimiri EERF2 YBR217W APG12 0.6 29 0.7 0.1682 0.241544841 iYBR216C 0.241832734 0.418972332 0.590154689 "APG12 -- autophagy -- conjugated to Apg5p, involved in autophagy and cytoplasm-to-vacuole targeting pathway" YBR237W PRP5 0.6 25 0.7 0.1682 0.11256259 iYBR236C 0.421316036 0.236492329 0.539106145 "PRP5 -- mRNA splicing -- Pre-mRNA processing RNA helicase of DEAD box family, snRNA-associated spliceosomal protein" YDR289C RTT103 0.6 30 0.7 0.1682 0.185453304 0.306124107 "RTT103 -- transposition (putative) -- Regulator of Ty1 transposition, has similarity to Spt8p" YDR391C YDR391C 0.6 28 0.7 0.1682 0.803760732 iYDR391C 0.851362871 0.864241349 0.438067785 YDR391C -- unknown -- unknown function YER144C UBP5 0.6 26 0.7 0.1682 0.373576012 iYER144C 0.537943055 0.345922817 0.642310541 "UBP5 -- unknown -- Ubiquitin-specific protease (ubiquitin C-terminal hydrolase), homologous to Doa4p and human Tre-2" YFL020C PAU5 0.6 32 0.7 0.1682 0.938017831 iYFL020C YFLWdelta1 0.330650212 0.561426722 0.567058812 0.317125598 0.329326906 PAU5 -- unknown -- Member of seripauperin (PAU) family YFL047W YFL047W 0.6 30 0.7 0.1682 0.713022641 iYFL048C 0.252454291 0.908203598 0.320885434 YFL047W -- unknown -- similarity to Rga2p YJL110C GZF3 0.6 27 0.7 0.1682 0.500214064 iYJL110C 0.739185812 0.696881092 0.958296362 "GZF3 -- nitrogen catabolism -- GATA-type zinc finger transcription factor, involved in nitrogen repression of Gat1p-dependent expression" YJR066W TOR1 0.6 27 0.7 0.1682 0.760837219 iYJR065C 0.239807647 0.556903432 0.160202655 "TOR1 -- signaling, cell cycle and meiosis -- Phosphatidylinositol kinase (PI kinase) homolog, involved in cell growth and sensitivity to the immunosuppressant rapamycin" YLL049W YLL049W 0.6 29 0.7 0.1682 0.411972247 iYLL050C 0.616791898 0.697286512 0.319996773 YLL049W -- unknown -- unknown function YMR178W YMR178W 0.6 29 0.7 0.1682 0.821276012 iYMR177W 0.074146026 0.96848603 0.148906994 YMR178W -- unknown -- unknown function YOL058W ARG1 0.6 30 0.7 0.1682 0.47639462 iYOL059W 0.461416237 0.469549084 0.258046302 ARG1 -- arginine biosynthesis -- Argininosuccinate synthetase (citrulline--aspartate ligase)catalyzes the penultimate step in arginine synthesis YOR385W YOR385W 0.6 30 0.7 0.1682 0.376604071 iYOR384W 0.356287405 0.140840526 0.487133984 YOR385W -- unknown -- unknown function YAR042W SWH1 0.4 23 0.7 0.1682 0.114561962 iYAR035W 0.290493367 0.130116017 0.04197925 SWH1 -- unknown -- unknown function with similarity to mammalian oxysterol-binding proteins YBL084C CDC27 0.4 25 0.7 0.1682 0.66196648 iYBL084C 0.815138387 0.538797005 0.521093813 "CDC27 -- cell cycle -- Component of anaphase-promoting complex (APC), required for the metaphase-anaphase transition and for Clb2p degradation" YBR007C YBR007C 0.4 23 0.7 0.1682 0.507677466 iYBR006W iYBR007C-0 0.394996587 0.194045354 0.64072327 0.562053281 0.235761705 YBR007C -- unknown -- unknown function YBR255W YBR255W 0.4 22 0.7 0.1682 0.034631454 iYBR254C 0.481852301 0.104817918 0.141857977 YBR255W -- unknown -- unknown function YBR272C HSM3 0.4 23 0.7 0.1682 0.07995753 iYBR272C 0.716919543 0.349490378 0.681889245 HSM3 -- mismatch repair -- functions in DNA mismatch repair YCL032W STE50 0.4 23 0.7 0.1682 0.25787848 iYCL033C 0.159255283 0.080664677 0.118093087 STE50 -- signaling -- feedback control of pheromone-induced signal transduction YCL073C 0.4 21 0.7 0.1682 0.867385611 iYCL073C 0.862365535 0.261238404 0.126576217 YCR028C FEN2 0.4 26 0.7 0.1682 0.526422658 iYCR028C YCR028C-A 0.295682933 0.600254993 0.750730994 0.627761533 0.664405427 "FEN2 -- unknown -- High affinity H+/pantothenate symporter, member of allantoate permease family of major facilitator superfamily (MFS)" YCR089W FIG2 0.4 22 0.7 0.1682 0.11893042 iYCR088W 0.46058591 0.088811809 0.792976856 FIG2 -- mating -- mating induction YDL028C MPS1 0.4 23 0.7 0.1682 0.187340015 iYDL028C 0.588299546 0.117067974 0.702245694 "MPS1 -- mitosis, checkpoint -- Serine/threonine/tyrosine protein kinase involved in spindle pole body duplication and in mitotic checkpoint" YDL101C DUN1 0.4 26 0.7 0.1682 0.767151615 iYDL101C 0.582981884 0.590758211 0.711323203 DUN1 -- DNA repair -- kinase required for induction of Rnr3p and DNA repair genes after DNA damage YDL119C YDL119C 0.4 24 0.7 0.1682 0.600372349 YDL119C -- unknown -- mitochondrial carrier family YDL142C CRD1 0.4 23 0.7 0.1682 0.509553393 iYDL142C 0.218272513 0.663823605 0.388172736 "CRD1 -- lipid biosynthesis -- Cardiolipin synthase, synthesizes cardiolipin from phosphatidylglycerol and CDP-diacylglycerol" YDR130C FIN1 0.4 21 0.7 0.1682 0.143460258 iYDR130C 0.501914244 0.633998404 0.525933694 "FIN1 -- unknown -- Intermediate filament protein, has possible coiled-coil region" YDR160W SSY1 0.4 23 0.7 0.1682 iYDR159W 0.286048133 0.456570802 "SSY1 -- transport -- Amino acid permease, indirectly controls expression of transporter genes such as BAP2, TAT1, PTR2, and BAP3" YDR209C YDR209C 0.4 22 0.7 0.1682 0.675160134 0.844559168 YDR209C -- unknown -- unknown function YFL025C BST1 0.4 24 0.7 0.1682 0.732808303 iYFL025C 0.395215713 0.909039639 0.514687731 "BST1 -- secretion -- negatively regulates COPII vesicle formation, required for proper vesicle cargo sorting" YFL054C YFL054C 0.4 22 0.7 0.1682 0.562277229 iYFL054C 0.196952449 0.701015147 0.613993711 "YFL054C -- unknown -- similarity to Fps1p and Aqy1p, member of major intrinsic protein (MIP) family of transmembrane channels" YGL133W ITC1 0.4 24 0.7 0.1682 0.565451683 iYGL134W 0.597170467 0.36444301 0.717108978 ITC1 -- unknown -- Subunit of Isw2 chromatin remodelling complex YGL197W MDS3 0.4 25 0.7 0.1682 0.398765698 iYGL198W 0.725610323 0.599415205 0.738969623 MDS3 -- meiosis -- Negative regulator of expression of early meiotic genes YGR130C YGR130C 0.4 25 0.7 0.1682 0.530896517 iYGR130C 0.078472285 0.638825704 0.222186752 YGR130C -- unknown -- similarity to Entamoeba histolytica myosin heavy chain PIR YJL009W YJL009W 0.4 26 0.7 0.1682 0.819111912 iYJL010C 0.485388053 0.834153424 0.485674939 "YJL009W -- unknown -- unknown function, overlaps with CCT8/YJL008C" YJL073W JEM1 0.4 22 0.7 0.1682 0.161749771 iYJL074C 0.434114078 0.169593941 0.443923925 JEM1 -- mating; nuclear fusion -- DnaJ-like the nuclear fusion step of karyogamy YJR006W HYS2 0.4 24 0.7 0.1682 0.382363179 iYJR005W 0.176862623 0.447309056 0.141528841 HYS2 -- DNA replication -- Small (58 kDa) subunit of DNA polymerase delta YJR062C NTA1 0.4 24 0.7 0.1682 0.455859291 iYJR062C 0.405049637 0.702186013 0.312575623 NTA1 -- protein degradation -- N-terminal amidase involved in the N-end rule pathway YKR031C SPO14 0.4 22 0.7 0.1682 0.131168213 iYKR031C 0.003858833 0.291697523 0.003373653 "SPO14 -- meiosis -- Phospholipase D, catalyzes hydrolysis of phosphatidylcholine to yield phosphatidic acid and choline" YKR064W YKR064W 0.4 22 0.7 0.1682 0.563737185 iYKR063C 0.277313172 0.835605388 0.50068565 "YKR064W -- unknown -- similarity to transcription factors, has Zn[2]-Cys[6] fungal-type binuclear cluster domain in the N-terminal region" YLR396C VPS33 0.4 22 0.7 0.1682 0.480583439 iYLR396C 0.914992013 0.674214262 0.746958432 "VPS33 -- vacuolar protein targeting -- Vacuolar sorting Sec1p family, essential for vacuolar morphogenesis and function" YLR408C YLR408C 0.4 23 0.7 0.1682 0.822701016 iYLR408C 0.825138297 0.399122107 0.760973663 YLR408C -- unknown -- unknown function YMR056C AAC1 0.4 24 0.7 0.1682 0.188536018 iYMR056C 0.660863108 0.503750998 0.536016778 AAC1 -- transport -- ADP/ATP carrier mitochondrial carrier (MCF) family YMR140W YMR140W 0.4 28 0.7 0.1682 0.447748856 iYMR139W 0.405866289 0.298043326 0.160684036 YMR140W -- unknown -- interacting with Snf1p and Reg1p YNL136W YNL136W 0.4 27 0.7 0.1682 0.023280789 iYNL137C 0.293057773 0.018611022 0.300748997 YNL136W -- unknown -- weak similarity to mature-parasite-infected erythrocyte surface antigen MESA from Plasmodium falciparum YNL167C SKO1 0.4 24 0.7 0.1682 0.21247115 iYNL167C 0.22249292 0.438329839 0.273060797 "SKO1 -- transcription -- Suppressor of protein kinase A (PKA) overexpression, homolog of mammalian ATF/CREB transcriptional repressor" YNL297C YNL297C 0.4 23 0.7 0.1682 0.321833157 0.583305171 YNL297C -- unknown -- unknown function YOL159C YOL159C 0.4 23 0.7 0.1682 0.747980495 iYOL159C YOLCdelta2 0.395154758 0.870930425 0.934096959 0.560015962 0.889811041 YOL159C -- unknown -- weak similarity to Ovis aries melatonin receptor YOR036W PEP12 0.4 25 0.7 0.1682 0.14021545 iYOR035C 0.085732813 0.092505241 0.028359652 PEP12 -- vacuolar protein targeting -- Syntaxin homolog (t-SNARE) involved in Golgi to vacuole transport YOR105W YOR105W 0.4 24 0.7 0.1682 0.376534894 0.072466081 YOR105W -- unknown -- unknown function YOR211C MGM1 0.4 24 0.7 0.1682 0.538105984 iYOR211C 0.378113733 0.416679968 0.704629943 "MGM1 -- mitochondrial genome maintenance -- Integral membrane mediates mitochondrial inheritance, member of dynamin family of GTPases" YOR216C RUD3 0.4 26 0.7 0.1682 0.021515436 iYOR216C 0.451985529 0.006747305 0.088489151 RUD3 -- secretion (putative) -- Hydrophilic vesicle docking YPL120W VPS30 0.4 24 0.7 0.1682 0.120223607 iYPL121C 0.296925912 0.315156893 0.472123751 "VPS30 -- vacuolar protein targeting -- sorting and delivery of soluble hydrolases to the vacuole, required for autophagy" YPL148C PPT2 0.4 24 0.7 0.1682 0.409606043 iYPL148C 0.382908594 0.892151327 0.712529928 "PPT2 -- lipid transport -- Acyl carrier-protein synthase, phosphopantetheine protein transferase" YPL161C BEM4 0.4 21 0.7 0.1682 0.886565682 iYPL161C 0.751955933 0.362632936 0.818773234 BEM4 -- bud emergence -- Bud emergence interacts with Rho-type GTPases YPL213W LEA1 0.4 24 0.7 0.1682 0.259996762 iYPL214C 0.476888578 0.502021857 "LEA1 -- mRNA splicing -- Component of U2 snRNP complex similar to human U2A' protein, involved in the initial steps of pre-mRNA splicing" YPR090W YPR090W 0.4 22 0.7 0.1682 0.359802493 YPR090W -- unknown -- unknown function YBL005W PDR3 0.3 20 0.7 0.1682 0.595914262 iYBL006C 0.502100337 0.348846654 0.662299092 "PDR3 -- transport -- Transcription factor related to Pdr1p, contains a Zn[2]-Cys[6] fungal-type binuclear cluster domain in the N-terminal region" YBL023C MCM2 0.3 19 0.7 0.1682 0.422966597 iYBL023C 0.735302988 0.744373639 0.650688183 MCM2 -- DNA replication -- Member of MCM/P1 family that acts as a complex at ARS sequences to initiate DNA replication YBL037W APL3 0.3 17 0.7 0.1682 0.586441065 iYBL038W 0.32941932 0.836582196 0.21588694 "APL3 -- secretion -- Alpha-adaptin, large subunit of clathrin-associated protein (AP) complex" YBL053W YBL053W 0.3 21 0.7 0.1682 0.54786104 iYBL054W 0.777601747 0.248662882 0.109670976 YBL053W -- unknown -- unknown function YBL086C YBL086C 0.3 17 0.7 0.1682 0.987055435 iYBL086C 0.885386609 0.246209098 0.733120511 YBL086C -- unknown -- unknown function YBL089W YBL089W 0.3 20 0.7 0.1682 0.647439321 iYBL090W 0.757358705 0.790152606 0.857701516 YBL089W -- unknown -- Membrane transporter of amino acid/auxin permease (AAAP) family YBR233W PBP2 0.3 18 0.7 0.1682 0.474240377 0.208251903 PBP2 -- unknown -- confers resistance to the antimalarial drug mefloquine when overproduced YDL197C ASF2 0.3 18 0.7 0.1682 0.253831878 iYDL197C 0.336763405 0.244795524 0.336936356 ASF2 -- transcription -- Anti-silencing causes depression of silent loci when overexpressed YDR013W YDR013W 0.3 20 0.7 0.1682 0.640271129 iYDR012W 0.800834853 0.89481245 0.669482933 YDR013W -- unknown -- unknown function YDR096W GIS1 0.3 20 0.7 0.1682 0.241817546 iYDR095C 0.412909881 0.205003249 0.532721468 "GIS1 -- unknown -- DNA damage-responsive repressor of PHR1, has two tandem C2H2-type zinc finger domains" YDR164C SEC1 0.3 17 0.7 0.1682 0.363914051 iYDR164C 0.729258102 0.890833299 0.889445672 SEC1 -- secretion -- Hydrophilic protein involved at the late stage of secretion YDR169C STB3 0.3 18 0.7 0.1682 0.081523879 iYDR169C-0 iYDR169C-1 0.503577458 0.639094095 0.211572227 0.669312833 0.883902675 STB3 -- unknown -- Sin3p-binding protein YDR200C YDR200C 0.3 19 0.7 0.1682 0.512983359 iYDR200C 0.227409272 0.593056664 0.07443393 "YDR200C -- unknown -- unknown function, has possible coiled-coil domain" YDR207C UME6 0.3 17 0.7 0.1682 0.286323785 iYDR207C 0.26210841 0.465043895 0.223483913 UME6 -- meiosis -- Global transcriptional regulator containing a zinc binuclear cluster domain involved in pathway specific repression or induction YDR249C YDR249C 0.3 19 0.7 0.1682 0.820990816 iYDR249C 0.458533551 0.902879729 0.612849162 YDR249C -- unknown -- weak similarity to cytochromes YDR277C MTH1 0.3 18 0.7 0.1682 0.836969096 iYDR277C 0.432015948 0.750837989 0.270710295 MTH1 -- hexose transport -- Repressor of hexose transport genes YDR383C YDR383C 0.3 17 0.7 0.1682 0.54136413 iYDR383C 0.630194177 0.699120755 0.345713129 YDR383C -- unknown -- unknown function YEL075C YEL075C 0.3 18 0.7 0.1682 0.96252226 iYEL075C 0.982131152 0.667756699 0.505881405 "YEL075C -- unknown -- similarity to other subtelomerically-encoded proteins including Yhl049p, Yil177p, and Yjl225p" YER013W PRP22 0.3 16 0.7 0.1682 0.520561852 iYER012W 0.733661076 0.422745411 0.776720174 "PRP22 -- mRNA splicing -- Pre-mRNA splicing factor of DEAH box family, required for release of mature mRNA from the spliceosome" YER170W ADK2 0.3 15 0.7 0.1682 0.685263043 iYER169W 0.398959587 0.904896346 0.172736062 ADK2 -- purine metabolism -- Adenylate kinase (GTP YER173W RAD24 0.3 21 0.7 0.1682 0.574656186 iYER172C 0.450573951 0.846704517 0.242117552 RAD24 -- DNA repair; cell cycle -- Nucleotide excision repair protein and checkpoint G2 arrest after DNA damage YFL034W YFL034W 0.3 19 0.7 0.1682 0.897267863 iYFL034C-A YFL034C-A 0.98892745 0.902407492 0.543651773 0.165523917 0.346827944 YFL034W -- unknown -- unknown function YFL055W AGP3 0.3 19 0.7 0.1682 0.329009792 iYFL056C-0 iYFL056C-1 0.158689971 0.351080058 0.742587818 0.185028726 0.541179318 AGP3 -- transport -- General amino acid permease with similarity to Gap1p and other amino acid permeases YFL065C YFL065C 0.3 17 0.7 0.1682 0.942460212 0.658627087 "YFL065C -- unknown -- similarity to other subtelomerically-encoded proteins including Yhl049p, Yil177p, Yjl225p, Yer190p, Yhr218p, and Yel076p" YFR021W YFR021W 0.3 16 0.7 0.1682 0.364838234 iYFR020W 0.611785656 0.839799952 0.549615694 YFR021W -- unknown -- unknown function YGL154C LYS5 0.3 18 0.7 0.1682 0.806422632 iYGL154C 0.536338537 0.890808854 0.374912648 "LYS5 -- lysine biosynthesis -- Alpha-aminoadipate reductase small chain, sixth step in lysine biosynthesis pathway" YGL174W YGL174W 0.3 17 0.7 0.1682 0.086033416 iYGL175C 0.347700356 0.092755036 0.624488503 YGL174W -- unknown -- unknown function YGL254W FZF1 0.3 17 0.7 0.1682 0.553774218 iYGL255W 0.535258362 0.758036645 0.375649773 "FZF1 -- sulfite metabolism -- Transcription factor involved in sulfite metabolism, has five C2H2-type zinc fingers" YGR015C YGR015C 0.3 14 0.7 0.1682 0.563913137 iYGR015C 0.41131974 0.842155835 0.383909853 YGR015C -- unknown -- unknown function YGR104C SRB5 0.3 16 0.7 0.1682 0.033913689 iYGR104C 0.261918161 0.188268156 0.330977908 SRB5 -- transcription -- Component of RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplexrequired for basal transcription YGR140W CBF2 0.3 19 0.7 0.1682 0.794950078 iYGR139W 0.258129881 0.543412612 0.376381383 CBF2 -- mitosis -- Component (subunit a) of Cbf3 kinetochore complex YHL010C YHL010C 0.3 15 0.7 0.1682 0.159505064 iYHL010C 0.114584786 0.781165204 0.516173268 YHL010C -- unknown -- Homolog of human breast cancer-associated protein BRAP2 protein YIL042C YIL042C 0.3 22 0.7 0.1682 0.386052339 iYIL042C 0.073313307 0.827861433 0.252238445 YIL042C -- unknown -- similarity to mitochondrial branched chain alpha-ketoacid and pyruvate dehydrogenase protein kinases YIL087C YIL087C 0.3 18 0.7 0.1682 0.163349155 0.588661236 YIL087C -- unknown -- unknown function YJL024C APS3 0.3 15 0.7 0.1682 0.614207551 iYJL024C itG(GCC)J1 0.580449393 0.689154462 0.502591953 0.38202791 0.926738142 APS3 -- vacuolar protein targeting -- Small subunit of clathrin-associated protein (AP) complex YJL039C NUP192 0.3 19 0.7 0.1682 0.621343916 iYJL039C itR(UCU)J2 0.737724003 0.807608011 0.323707349 0.752517869 0.890472824 NUP192 -- nuclear protein targeting -- Nuclear pore protein (nucleoporin) located at the inner site of nuclear pores YJL095W BCK1 0.3 16 0.7 0.1682 0.358658116 iYJL096W 0.814466124 0.738556953 0.496696745 "BCK1 -- signaling, PKC1 pathway -- Serine/threonine protein kinase of MEKK family involved in the cell wall integrity (low-osmolarity) and nutrient sensing pathways" YJL116C NCA3 0.3 20 0.7 0.1682 0.110632125 iYJL116C 0.215122068 0.303013213 0.303460515 NCA3 -- ATP synthesis -- regulation of synthesis of Atp6p and Atp8p YJR156C THI11 0.3 17 0.7 0.1682 0.368038381 iYJR156C 0.411945666 0.621291402 0.637031125 "THI11 -- pyrimidine biosynthesis -- Biosynthetic enzyme involved in pyrimidine biosynthesis pathway, involved in conversion of hydroxymethyl-pyrimidine precursor to thymidineThi5p, Thi11p, Thi12p and Thi13p are nearly identical" YKL020C SPT23 0.3 21 0.7 0.1682 0.420348616 iYKL020C 0.078888847 0.440832459 0.282836864 SPT23 -- transcription -- Transcription factor required for transcription of a subset of genesfunctionally redundant with Mga2p YKL098W YKL098W 0.3 17 0.7 0.1682 0.791789564 iYKL099C 0.538981092 0.895614955 0.727864143 YKL098W -- unknown -- unknown function YKL208W CBT1 0.3 16 0.7 0.1682 0.269097371 iYKL209C tT(CGU)K 0.394399308 0.664897092 0.549561053 0.48028731 0.233979255 "CBT1 -- mRNA processing, COB mRNA -- 3' end processing of mitochondrial COB mRNA" YKR050W TRK2 0.3 18 0.7 0.1682 0.253868665 iYKR049C 0.176103804 0.645877009 0.303849903 "TRK2 -- transport -- Potassium transporter of plasma membrane, moderate affinity, member of potassium transporter family of membrane transporters" YLR040C YLR040C 0.3 21 0.7 0.1682 0.261295534 0.367517957 "YLR040C -- unknown -- Possible cell wall protein, has weak similarity to seripauperin (PAU) family of possible cell wall mannoproteins" YLR087C YLR087C 0.3 19 0.7 0.1682 0.371172651 iYLR087C 0.439511424 0.488505284 0.609893651 YLR087C -- unknown -- normal growth rate and resistance to NaCl and H2O2 YLR117C CLF1 0.3 19 0.7 0.1682 0.404889627 iYLR117C 0.416335147 0.597483262 0.220830008 "CLF1 -- cell cycle (putative) -- Essential pre-mRNA splicing factor with similarity to Drosophila crooked neck (crn) protein, has tetratricopeptide (TPR) repeats" YLR128W YLR128W 0.3 17 0.7 0.1682 0.305003994 iYLR127C 0.628976541 0.586850983 0.260089823 YLR128W -- unknown -- unknown function YLR165C YLR165C 0.3 19 0.7 0.1682 0.556581294 iYLR165C 0.728448702 0.744558155 0.628457028 "YLR165C -- unknown -- Pseudouridine synthase which acts on mitochondrial 21S RNA, member of RluA-family of pseudouridine synthases" YLR246W ERF2 0.3 19 0.7 0.1682 0.467739301 iYLR245C 0.491133442 0.842893974 0.752658717 ERF2 -- signaling (putative) -- palmitoylation and localization of Ras2p YLR317W YLR317W 0.3 20 0.7 0.1682 0.454234918 0.614779874 YLR317W -- unknown -- unknown functionquestionable ORF YLR324W YLR324W 0.3 20 0.7 0.1682 0.668426952 iYLR323C 0.629225118 0.6729854 0.427952634 YLR324W -- unknown -- unknown function YLR368W YLR368W 0.3 18 0.7 0.1682 0.328277761 iSNR44 0.920411429 0.455887491 0.917304369 "YLR368W -- unknown -- unknown function, contains an F-box" YMR174C PAI3 0.3 18 0.7 0.1682 0.189942305 iYMR174C 0.117453171 0.242138867 0.146383609 PAI3 -- osmotic stress response -- Proteinase A (yscA) inhibitor IA3 YMR185W YMR185W 0.3 18 0.7 0.1682 0.313866682 iYMR184W 0.399970581 0.882086728 0.082843277 YMR185W -- unknown -- unknown function YNL083W YNL083W 0.3 15 0.7 0.1682 0.233590947 iYNL084C 0.104502111 0.375126732 0.06645209 YNL083W -- unknown -- Member of mitochondrial carrier (MCF) family of membrane transporters YNL106C INP52 0.3 19 0.7 0.1682 0.317920789 0.34205546 INP52 -- endocytosis (putative) -- Dual functional inositol polyphosphate phosphatase YNL331C AAD14 0.3 17 0.7 0.1682 iYNL331C 0.308494737 0.220150988 "AAD14 -- unknown -- Putative aryl alcohol dehydrogenase, may participate in late steps of degradation of aromatic compounds that arise from the degradation of lignocellulose" YOL066C RIB2 0.3 18 0.7 0.1682 0.141651258 iYOL066C 0.538118048 0.346209098 0.09046767 "RIB2 -- riboflavin biosynthesis -- DRAP deaminase, part of riboflavin biosynthesis pathway" YOL105C WSC3 0.3 19 0.7 0.1682 0.108087566 iYOL105C 0.444182472 0.058733484 0.425475346 WSC3 -- signaling -- maintenance of cell wall integrity and for the stress response YOL106W YOL106W 0.3 15 0.7 0.1682 0.59336446 iYOL107W 0.345926358 0.781598513 0.184367914 YOL106W -- unknown -- unknown function YOR258W YOR258W 0.3 15 0.7 0.1682 0.394999802 iYOR257W 0.545649205 0.681818182 0.337833578 YOR258W -- unknown -- unknown function YOR289W YOR289W 0.3 19 0.7 0.1682 0.328718849 iYOR288C 0.572447103 0.394295843 0.525137826 YOR289W -- unknown -- unknown function YPL080C YPL080C 0.3 15 0.7 0.1682 0.963801095 iYPL080C 0.965890967 0.479010375 0.473357792 YPL080C -- unknown -- unknown function YPL133C YPL133C 0.3 16 0.7 0.1682 0.578041787 iYPL133C 0.840626776 0.514126097 0.712992677 "YPL133C -- unknown -- similarity to transcription factors, has Zn[2]-Cys[6] fungal-type binuclear cluster domain in the N-terminal region" YPL236C YPL236C 0.3 17 0.7 0.1682 0.305296097 iYPL236C 0.415252046 0.797525938 0.742921675 YPL236C -- unknown -- Serine/threonine protein kinase of unknown function YPR003C YPR003C 0.3 16 0.7 0.1682 0.373180123 iYPR003C 0.502513763 0.428606238 0.230261038 "YPR003C -- unknown -- similarity to Sul1p, member of sulfate permease family of membrane transporters" YPR012C 0.3 18 0.7 0.1682 YPR032W SRO7 0.3 18 0.7 0.1682 0.170634598 iYPR031W 0.644705659 0.5461203 0.852826511 SRO7 -- signaling (putative) -- functions together with Sec9p in exocytosis downstream of Rho3p GTPase YPR085C YPR085C 0.3 18 0.7 0.1682 0.318033923 iYPR085C 0.237089202 0.360341332 0.13471001 YPR085C -- unknown -- unknown function YPR121W THI22 0.3 16 0.7 0.1682 0.579638366 itC(GCA)P2 iYPR120C 0.362774997 0.269847765 0.936809617 0.333145116 0.435427926 "THI22 -- thaimine metabolism -- Bipartite protein consisting of N-terminal hydroxymethylpyrimidine phosphate (HMP-P) kinase domain, needed for thiamine biosynthesis, fused to C-terminal Pet18p-like domain of indeterminant function" YPR126C YPR126C 0.3 15 0.7 0.1682 0.340292103 iYPR126C 0.508557068 0.463191875 0.359649123 "YPR126C -- unknown -- unknown function, questionable ORF" YPR186C PZF1 0.3 15 0.7 0.1682 0.097787179 iYPR186C 0.502021094 0.15872624 0.340813078 "PZF1 -- transcription -- RNA polymerase III transcription initiation factor TFIIIA, has nine C2H2-type zinc fingers" YAL047C SPC72 0.2 12 0.7 0.1682 0.486360666 iYAL047C 0.529109479 0.477174781 0.69029971 SPC72 -- cytoskeleton -- Component of spindle pole body that interacts with Stu2p YDL194W SNF3 0.2 15 0.7 0.1682 0.167933344 iYDL195W 0.38245102 0.28165885 0.299226555 "SNF3 -- transport -- High-affinity glucose transporter responsible for induction of gene expression in the presence of low glucose, member of hexose transporter family of major facilitator superfamily (MFS)" YDL240W LRG1 0.2 14 0.7 0.1682 iYDL241W-0 iYDL241W-1 0.76694163 0.256927207 0.78890054 0.47980846 "LRG1 -- sporulation -- GTPase-activating rho/rac family, expressed highest in sporulating cells, contains LIM domains" YDR014W YDR014W 0.2 13 0.7 0.1682 0.564273655 iYDR013W 0.53528405 0.366861545 0.555931058 YDR014W -- unknown -- unknown function YDR279W YDR279W 0.2 12 0.7 0.1682 0.740490496 itE(CUC)D-0 itE(CUC)D-1 0.613369892 0.19944925 0.922839506 0.973251692 0.596149099 YDR279W -- unknown -- unknown function YDR419W RAD30 0.2 12 0.7 0.1682 0.612070927 iYDR418W 0.826445606 0.79597141 0.781662907 "RAD30 -- DNA repair -- DNA polymerase pol-eta, which can replicate efficiently past a thymine-thymine cis-syn cyclobutane dimer" YDR530C APA2 0.2 16 0.7 0.1682 0.346112114 iYDR530C 0.491280253 0.67894559 0.326257862 APA2 -- purine metabolism -- ATP adenylyltransferase II YER007W PAC2 0.2 13 0.7 0.1682 0.396582637 iYER006W 0.424062138 0.434549461 0.587596969 "PAC2 -- mitosis -- Putative tubulin-specific chaperone, involved in formation of alpha-beta-tubulin heterodimer" YER188W YER188W 0.2 9 0.7 0.1682 0.865033507 iYER187W 0.758406647 0.869034318 0.08001936 "YER188W -- unknown -- unknown function, induced during anaerobic growth" YFR008W YFR008W 0.2 12 0.7 0.1682 0.432686994 iYFR007W 0.110166748 0.584038308 YFR008W -- unknown -- unknown function YGL057C YGL057C 0.2 13 0.7 0.1682 0.834463614 iYGL057C 0.544231006 0.845713825 0.378691141 YGL057C -- unknown -- unknown function YGR129W SYF2 0.2 14 0.7 0.1682 0.184822906 iYGR128C 0.440337556 0.416525853 0.604097766 SYF2 -- cell cycle (putative) -- possible involvement in pre-mRNA splicing YGR133W PEX4 0.2 14 0.7 0.1682 0.425951832 iYGR132C 0.253742934 0.870457722 0.197851153 "PEX4 -- protein degradation, ubiquitin-mediated -- Ubiquitin-conjugating enzyme and peroxisomal biogenesis protein (peroxin)" YHL044W YHL044W 0.2 14 0.7 0.1682 0.54979305 iYHL045W 0.376880395 0.913567438 0.54850145 "YHL044W -- unknown -- similarity to subtelomerically-encoded proteins such as Cos5p, Ybr302p, Cos3p, Cos1p, Cos4p, Cos8p, Cos6p, Cos9p" YHR100C YHR100C 0.2 14 0.7 0.1682 0.216774114 iYHR100C 0.601751549 0.505444866 0.383997972 YHR100C -- unknown -- unknown function YHR105W YHR105W 0.2 13 0.7 0.1682 0.279049784 iYHR104W 0.312592568 0.470391061 0.216563027 YHR105W -- unknown -- similarity to Grd19p and bacterial helix-turn-helix regulator argR group YIR033W MGA2 0.2 14 0.7 0.1682 0.441934889 iYIR032C 0.303295619 0.597161203 0.272404614 MGA2 -- transcription -- may be involved in the remodeling chromatin structure YJL100W YJL100W 0.2 14 0.7 0.1682 0.425574359 iYJL101C 0.271819437 0.847223743 0.381543922 YJL100W -- unknown -- unknown function YKR004C ECM9 0.2 14 0.7 0.1682 0.901499035 iYKR004C 0.295686462 0.991272264 0.45914589 ECM9 -- cell wall biogenesis -- Protein possibly involved in cell wall structure or biosynthesis YMR234W RNH1 0.2 14 0.7 0.1682 0.365876203 iYMR233W 0.208238067 0.807937404 0.24352666 "RNH1 -- DNA replication (putative) -- Ribonuclease H, endonuclease that degrades RNA in RNA-DNA hybrids" YNL328C MDJ2 0.2 12 0.7 0.1682 0.90184735 iYNL328C 0.899702578 0.765921788 0.284217641 "MDJ2 -- protein folding -- import and folding of mitochondrial proteinshas similarity to E. coli DnaJ and other DnaJ-like proteins, function partially overlaps that of Mdj1p" YNR045W PET494 0.2 15 0.7 0.1682 0.118740704 iYNR044W 0.40259591 0.38373515 0.254819046 PET494 -- protein synthesis -- Translational activator required for mitochondrial translation of COX3 mRNA YOL150C YOL150C 0.2 14 0.7 0.1682 0.588128759 iYOL150C 0.285022045 0.64781802 0.343043481 YOL150C -- unknown -- unknown functionquestionable ORF YOR077W RTS2 0.2 14 0.7 0.1682 0.39447137 iYOR076C 0.563859239 0.911173184 0.663926576 "RTS2 -- unknown -- similarity to mouse KIN17 protein, has a single C2H2-type zinc finger" YOR087W YOR087W 0.2 12 0.7 0.1682 0.697100538 iYOR086C itN(GUU)O2 0.759457355 0.644670068 0.952223655 0.491041404 0.495557645 YOR087W -- unknown -- unknown function YOR324C YOR324C 0.2 13 0.7 0.1682 0.321664219 0.520705769 YOR324C -- unknown -- unknown function YOR334W MRS2 0.2 14 0.7 0.1682 0.404452476 0.381813417 "MRS2 -- mRNA splicing, mitochondrial -- splicing of mitochondrial group II intronsalso involved in a mitochondrial function unrelated to splicing" YPL041C YPL041C 0.2 11 0.7 0.1682 0.24679937 iYPL041C 0.515373397 0.409356725 0.600131384 YPL041C -- unknown -- unknown function YPL076W GPI2 0.2 14 0.7 0.1682 0.408924559 iYPL077C 0.690891551 0.169432807 0.528353634 GPI2 -- protein processing -- synthesis of N-acetylglucosaminyl phosphatidylinositol YPR066W UBA3 0.2 13 0.7 0.1682 0.790501374 iYPR065W 0.249423379 0.931437319 0.34393931 "UBA3 -- protein degradation, Rub1p-mediated -- Rub1-activating enzyme, similar to ubiquitin-activating E1-like proteins" YLR289W GUF1 0.3 23 0.6 0.1311 1 0.439647128 iYLR288C 0.827774579 0.552637623 0.701298701 GUF1 -- unknown -- similarity to E. coli elongation factor-type GTP-binding protein LepA YER032W FIR1 0.3 20 0.6 0.1311 1 0.957366351 iYER031C 0.969337599 0.647921366 0.112043236 "FIR1 -- mRNA 3'-end processing -- Protein probably involved in 3'-mRNA processinginteracts with Pap1p and Ref2p," YHR033W YHR033W 0.3 18 0.6 0.1311 1 0.91033014 iYHR032W 0.978160266 0.67472119 0.443313462 YHR033W -- unknown -- similarity to Pro1p YEL057C YEL057C 0.2 11 0.6 0.1311 1 0.798063324 iYEL057C 0.959510459 0.65387071 0.8471668 YEL057C -- unknown -- unknown function YLL041C SDH2 1.1 71 0.6 0.1311 0.21470851 iYLL041C 0.201906471 0.476971708 0.175418994 "SDH2 -- TCA cycle, oxidative phosphorylation -- Succinate dehydrogenase (ubiquinone) iron-sulfur protein (Ip) subunit, converts succinate + ubiquinone to fumarate + ubiquinol in the TCA cycle" YPL260W YPL260W 1 58 0.6 0.1311 0.254871708 0.482778091 YPL260W -- unknown -- unknown function YLR454W YLR454W 0.9 54 0.6 0.1311 0.088862138 iYLR453C 0.743011893 0.103448276 0.76579117 YLR454W -- unknown -- unknown function YML131W YML131W 0.9 50 0.6 0.1311 0.472525032 iYML132W-0 iYML132W-1 0.706979746 0.497823008 0.630196584 0.527304993 0.237914921 YML131W -- unknown -- Putative NAD-dependent oxidoreductase YBR211C AME1 0.8 47 0.6 0.1311 0.263451265 iYBR211C 0.137976929 0.5023451 0.239493426 "AME1 -- unknown -- Actin-related protein, regulator of microtubule stability" YEL021W URA3 0.7 44 0.6 0.1311 0.328896959 iYEL022W 0.513197564 0.60159523 0.451673164 "URA3 -- pyrimidine biosynthesis -- Orotidine-5'-phosphate decarboxylase, catalyzes sixth step of pyrimidine biosynthesis pathway" YGL049C TIF4632 0.7 40 0.6 0.1311 0.579758712 iYGL049C 0.3569967 0.587195066 0.155457925 TIF4632 -- protein synthesis -- mRNA cap-binding protein (eIF4F) 130K subunit YLR430W SEN1 0.7 42 0.6 0.1311 0.354295414 iYLR429W 0.686400384 0.144389772 0.94635799 "SEN1 -- tRNA splicing -- DEAD-box type RNA helicase and positive effector of tRNA-splicing endonuclease required for intron cleavage for all 10 precursor tRNA families, involved in snRNA and snoRNA maturation" YML059C YML059C 0.7 41 0.6 0.1311 0.376367131 iYML059C 0.495283635 0.226584914 0.18366922 YML059C -- unknown -- unknown function YOL036W YOL036W 0.7 38 0.6 0.1311 0.482328269 0.662423461 YOL036W -- unknown -- unknown function YBR170C NPL4 0.6 36 0.6 0.1311 0.458211294 iYBR170C 0.449703662 0.847221102 0.624431449 NPL4 -- nuclear protein targeting -- Nuclear pore protein YDR350C TCM10 0.6 38 0.6 0.1311 0.707035754 iYDR350C 0.424165425 0.898797921 0.440106477 TCM10 -- unknown -- unknown function YDR351W SBE2 0.6 36 0.6 0.1311 0.365559412 iYDR350C 0.424165425 0.574561404 0.440106477 SBE2 -- bud growth -- Golgi cell wall formation YFR003C YFR003C 0.6 32 0.6 0.1311 0.45619875 iYFR003C 0.101399638 0.623220604 0.09657245 "YFR003C -- unknown -- unknown function, may physically interact with Glc7p and Ppz1p" YFR040W SAP155 0.6 33 0.6 0.1311 0.241531622 iYFR039C 0.164040776 0.501098344 0.168534763 SAP155 -- cell cycle -- Sit4p-associated protein YGR080W TWF1 0.6 30 0.6 0.1311 0.548169976 iYGR079W 0.597390628 0.874542044 0.526315789 "TWF1 -- cytoskeleton -- Twinfilin A, member of a family of proteins that sequester actin monomers" YIL151C YIL151C 0.6 33 0.6 0.1311 0.572694659 iYIL151C 0.430466768 0.804337232 0.540469753 YIL151C -- unknown -- strong similarity to Ykr096p YIR003W YIR003W 0.6 35 0.6 0.1311 0.388376234 iYIR002C 0.387719217 0.640594542 0.629668468 YIR003W -- unknown -- similarity to E. coli and Bacillus subtilis MinD YKL101W HSL1 0.6 37 0.6 0.1311 0.321204329 iYKL102C 0.395260608 0.380760554 0.455607477 HSL1 -- cell cycle -- Serine/threonine protein kinase that genetically interacts with histone mutants YKL173W SNU114 0.6 40 0.6 0.1311 0.576370699 iYKL174C 0.216426942 0.736145842 0.080925778 SNU114 -- mRNA splicing -- Component of U5 small nuclear ribonucleoprotein (U5 snRNP) required for pre-mRNA splicing YKR069W MET1 0.6 36 0.6 0.1311 0.338637655 iYKR068C 0.181868448 0.413775409 0.521269739 MET1 -- methionine biosynthesis -- Siroheme synthase involved in methionine metabolism YOL016C CMK2 0.6 35 0.6 0.1311 0.442184748 iYOL016C 0.530160256 0.35702186 0.837394319 CMK2 -- signaling -- Calcium/calmodulin-dependent serine/threonine protein kinase (CaM kinase) type II YOL087C YOL087C 0.6 37 0.6 0.1311 0.288869043 iYOL087C 0.562652134 0.504234896 0.269416694 "YOL087C -- unknown -- unknown function, has one WD (WD-40) domain" YPL188W POS5 0.6 33 0.6 0.1311 0.506663314 iYPL189W 0.614259124 0.610135674 0.296009577 POS5 -- unknown -- similarity to Utr1p and Yel041p YAL017W YAL017W 0.4 29 0.6 0.1311 0.365064138 iYAL018C 0.217685725 0.606921029 0.056773879 YAL017W -- unknown -- Serine/threonine protein kinasehas similarity to human PIM-1 oncogene YDR202C RAV2 0.4 26 0.6 0.1311 0.619652013 0.797126228 "RAV2 -- unknown -- unknown function, involved in regulation of vacuolar H+-ATPase assembly" YDR467C YDR467C 0.4 28 0.6 0.1311 0.564820103 iYDR467C 0.264892843 0.462186802 0.324997983 YDR467C -- unknown -- unknown function YER008C SEC3 0.4 32 0.6 0.1311 0.593488674 iYER008C 0.611858725 0.614485981 0.844135802 SEC3 -- secretion -- Component of exocyst complex required for exocytosis YER172C BRR2 0.4 30 0.6 0.1311 0.559510809 iYER172C 0.450573951 0.602242478 0.242117552 BRR2 -- mRNA splicing -- RNA helicase-related pre-mRNA splicing YFL029C CAK1 0.4 28 0.6 0.1311 0.332731466 iYFL029C 0.209591991 0.660650983 0.320230608 "CAK1 -- cell cycle -- Cdk-activating kinase (serine/threonine protein kinase) responsible for in vivo activation of Cdc28p, also involved in spore wall formation" YGL017W ATE1 0.4 23 0.6 0.1311 0.270253893 iYGL018C 0.239824931 0.883000798 0.161287597 "ATE1 -- protein synthesis -- Arginyltransferase (arg-tRNA protein transferase), transfers arg to N-asp or N-glu of proteins prior to degradation by the N-end rule pathway" YGL104C YGL104C 0.4 27 0.6 0.1311 0.968217351 iYGL104C IntYGL103W 0.992609447 0.95278586 0.835913807 0.337231969 0.733564572 "YGL104C -- unknown -- Putative hexose transporter, member of hexose transporter family of major facilitator superfamily (MFS)" YGL188C YGL188C 0.4 28 0.6 0.1311 0.987581892 iYGL188C 0.960822406 0.85339186 0.650199521 YGL188C -- unknown -- unknown function YGR002C YGR002C 0.4 27 0.6 0.1311 0.403006673 iYGR002C 0.592459242 0.720767151 0.554677857 YGR002C -- unknown -- similarity to Drosophila melanogaster transcription initiation factor IID 230 K chain PIR YGR215W YGR215W 0.4 28 0.6 0.1311 0.720748206 iYGR214W 0.728412635 0.539878337 0.661771748 YGR215W -- unknown -- unknown function YGR217W CCH1 0.4 30 0.6 0.1311 0.678353753 iYGR216C 0.662659153 0.565903964 0.299122107 CCH1 -- transport -- Putative voltage-gated calcium channel YKR051W YKR051W 0.4 28 0.6 0.1311 0.375164216 iYKR050W 0.215732471 0.813955623 0.512301363 YKR051W -- unknown -- unknown function YLL006W MMM1 0.4 27 0.6 0.1311 0.659477772 iYLL007C 0.189643907 0.889146049 0.223064645 "MMM1 -- mitochondrial biogenesis -- essential for establishment and maintenance of mitochondrial shape and structure, involved in coupling mitochondria to the actin cytoskeleton" YLR055C SPT8 0.4 26 0.6 0.1311 0.16890941 iYLR055C 0.145100604 0.086988304 0.070314215 SPT8 -- chromatin structure -- Component of nucleosomal histone acetyltransferase complex (Spt-Ada-Gcn5-Acetyltransferase or SAGA) complexmember of TBP class of SPT proteins YLR163C MAS1 0.4 26 0.6 0.1311 0.522295411 iYLR163C 0.517843662 0.839984038 0.756664006 MAS1 -- protein processing -- Beta (enhancing) subunit of mitochondrial processing peptidase YLR362W STE11 0.4 26 0.6 0.1311 0.252270422 iYLR361C 0.161275988 0.405642161 0.52612566 "STE11 -- signaling, pheromone and pseudohyphal growth pathways -- MAP kinase kinase kinase (MAPKKK or MEKK), component of pheromone response, filamentous growth, high-osmolarity sensing, and STE vegetative growth pathways" YLR376C YLR376C 0.4 26 0.6 0.1311 0.55372375 iYLR376C 0.764781402 0.66334731 0.362404991 YLR376C -- unknown -- unknown function YLR422W YLR422W 0.4 28 0.6 0.1311 0.334957349 iYLR421C 0.252145054 0.263535288 0.435612606 YLR422W -- unknown -- unknown function YNR006W VPS27 0.4 24 0.6 0.1311 0.261413291 0.375851619 VPS27 -- vacuolar protein targeting -- vacuolar sortingmutants develop a prominent novel pre-vacuolar organelle YOL137W YOL137W 0.4 26 0.6 0.1311 0.238088179 iYOL138C 0.435265297 0.342007435 0.836988304 YOL137W -- unknown -- unknown function YOL154W YOL154W 0.4 24 0.6 0.1311 0.57123199 iYOL155C-0 iYOL155C-1 0.532755277 0.570156811 0.788993292 0.500120997 0.539969347 YOL154W -- unknown -- similarity to Zinc metalloproteinases YOR018W ROD1 0.4 26 0.6 0.1311 0.396536235 iYOR017W 0.360111597 0.736032255 0.671769256 ROD1 -- drug resistance -- mediates resistance to o-dinitrobenzene (O-DNB) YOR031W CRS5 0.4 26 0.6 0.1311 0.748306065 iYOR030W 0.411040958 0.784940601 0.564389948 CRS5 -- Cu2+ ion homeostasis -- Metallothionein-like provides copper resistance in the absence of Cup1p YOR076C SKI7 0.4 27 0.6 0.1311 0.300239432 iYOR076C 0.563859239 0.541421312 0.663926576 SKI7 -- unknown -- Antiviral represses replication of double-stranded RNA viruses YOR219C STE13 0.4 25 0.6 0.1311 0.138845226 iYOR219C 0.500093081 0.4648235 0.278293135 "STE13 -- mating -- Dipeptidyl aminopeptidase A (DPAP A, yscIV) involved in maturation of alpha-factor" YOR372C NDD1 0.4 30 0.6 0.1311 0.427402706 iYOR372C 0.053332244 0.175512219 0.02274204 NDD1 -- mitosis (putative) -- nuclear divisionpositively but indirectly affects transcription of a subset of genes required for the cell cycle YOR394W YOR394W 0.4 25 0.6 0.1311 0.949293488 iYOR393W 0.943187172 0.402416357 0.172138421 YOR394W -- unknown -- Member of seripauperin (PAU) family (YPL282C and YOR394W code for identical proteins) YPL071C YPL071C 0.4 25 0.6 0.1311 0.201635098 iYPL071C 0.363290693 0.369353551 0.536960286 YPL071C -- unknown -- unknown function YPR075C OPY2 0.4 29 0.6 0.1311 0.467647628 0.428269686 OPY2 -- signaling (putative) -- may be involved in cell-cycle regulationoverproduction causes insensitivity to alpha-factor arrest YPR081C YPR081C 0.4 24 0.6 0.1311 0.319380945 iYPR081C 0.437062807 0.251789682 0.543291098 YPR081C -- unknown -- strong similarity to glycyl-tRNA synthetases YAL043C PTA1 0.3 22 0.6 0.1311 0.56646588 iYAL043C 0.644458227 0.552847659 0.797552627 "PTA1 -- tRNA processing -- Component of pre-mRNA cleavage factor II (CFII), required for both cleavage and polyadenylation of mRNA precursor" YBR012C YBR012C 0.3 24 0.6 0.1311 0.665707424 0.758056719 "YBR012C -- unknown -- unknown function, has a peroxisomal targeting signal" YBR193C MED8 0.3 20 0.6 0.1311 0.315698512 iYBR193C 0.369012599 0.202793296 0.451396648 MED8 -- transcription -- Component of RNA polymerase II holoenzyme and mediator subcomplex YBR259W YBR259W 0.3 19 0.6 0.1311 0.180508337 iYBR258C 0.538111332 0.795186416 0.648646471 YBR259W -- unknown -- unknown function YCR061W YCR061W 0.3 19 0.6 0.1311 0.368630346 iYCR060W 0.346718387 0.676332034 0.103206574 YCR061W -- unknown -- unknown function YCR086W YCR086W 0.3 18 0.6 0.1311 0.210791605 iYCR085W 0.478011976 0.525990903 0.160947914 YCR086W -- unknown -- Protein possibly involved in sporulation YDL059C RAD59 0.3 18 0.6 0.1311 0.469184548 iYDL059C 0.27118792 0.414921044 0.575179569 RAD59 -- DNA repair and recombination -- Homolog of Rad52p involved in homologous recombination and DNA repair YDR138W HPR1 0.3 24 0.6 0.1311 0.19842517 iYDR137W 0.38217033 0.309131332 0.822188205 "HPR1 -- mitosis, recombination -- Recombination protein related to Top1pinvolved in maintaining stability of direct repeat sequences" YDR205W YDR205W 0.3 18 0.6 0.1311 0.259674891 iYDR204W 0.188755161 0.879083649 0.208028664 YDR205W -- unknown -- Member with Cot1p of cation diffusion facilitator (CDF) family of membrane transporters YDR227W SIR4 0.3 18 0.6 0.1311 0.612659756 iYDR226W 0.621689387 0.499876574 0.491779729 "SIR4 -- silencing -- Coiled-coil maintenance of silencing of HMR, HML, and telomeres" YDR379W RGA2 0.3 23 0.6 0.1311 0.465401803 iYDR378C 0.285153998 0.650678372 0.502540937 RGA2 -- signaling -- Rho-GTPase activating protein YDR423C CAD1 0.3 18 0.6 0.1311 0.45791963 iYDR423C 0.276070071 0.689083821 0.152912999 "CAD1 -- transcription -- Transcriptional activator of basic leucine zipper (bZIP) family, involved in regulation of multidrug resistance" YDR436W PPZ2 0.3 18 0.6 0.1311 0.23647137 iYDR435C 0.217921256 0.381694954 0.39377494 "PPZ2 -- stress response -- Protein serine/threonine phosphatase involved in osmoregulation, member of PPP family of protein phosphatases and related to PP1 phosphatases" YDR438W YDR438W 0.3 18 0.6 0.1311 0.468154312 iYDR437W 0.060094683 0.682726394 0.134259259 YDR438W -- unknown -- unknown function YDR485C YDR485C 0.3 21 0.6 0.1311 0.294564868 iYDR485C 0.311336165 0.235820174 0.110534717 "YDR485C -- unknown -- similarity to human YL-1 protein, GB" YDR499W YDR499W 0.3 18 0.6 0.1311 0.754196255 iYDR498C 0.33257907 0.814126097 0.110429943 YDR499W -- unknown -- unknown function YER140W YER140W 0.3 21 0.6 0.1311 0.459358819 iYER139C 0.121181881 0.894859813 0.252616734 YER140W -- unknown -- unknown function YER162C RAD4 0.3 20 0.6 0.1311 0.095707583 iYER162C 0.150057842 0.201729974 0.238767444 "RAD4 -- DNA repair, nucleotide excision -- Component of nucleotide excision repairosome, homolog of human XPC xeroderma pigmentosum gene product" YER175C YER175C 0.3 20 0.6 0.1311 0.431920905 iYER175C 0.388848002 0.583467612 0.541008701 "YER175C -- unknown -- predicted S-adenosylmethionine-dependent methyltransferase motif, has similarity to Yhr209ptranscription induced by the drug FK506 in a GCN4-dependent manner" YFL064C YFL064C 0.3 17 0.6 0.1311 0.978890506 iYFL064C 0.996902638 0.877873679 0.103860936 "YFL064C -- unknown -- similarity to other subtelomerically-encoded proteins including Yhl049p, Yil177p, Yjl225p, Yer189p, Yel075p, and Yer190p" YFR007W YFR007W 0.3 19 0.6 0.1311 0.300489644 iYFR006W itF(GAA)F 0.582654467 0.323134208 0.824899202 0.279550806 YFR007W -- unknown -- unknown function YGL124C YGL124C 0.3 23 0.6 0.1311 0.910818955 iYGL124C 0.991165154 0.781007097 0.246331237 YGL124C -- unknown -- unknown function YGL125W MET13 0.3 21 0.6 0.1311 0.788028306 iYGL126W 0.27519754 0.909417398 0.421702404 "MET13 -- methionine metabolism -- Methylenetetrahydrofolate reductase (MTHFR), essential for methionine biosynthesis" YGL143C MRF1 0.3 22 0.6 0.1311 0.471492315 iYGL143C 0.273250389 0.900271538 0.112591548 MRF1 -- protein synthesis -- Mitochondrial peptide chain release factordirects termination of translation in response to termination codons UAA and UAG YGL229C SAP4 0.3 23 0.6 0.1311 0.52240734 iYGL229C 0.081517807 0.887447631 0.109286009 SAP4 -- cell cycle -- Sit4p-associated protein YHR186C YHR186C 0.3 21 0.6 0.1311 0.416157517 iYHR186C 0.474843113 0.772282494 0.196902476 "YHR186C -- unknown -- weak similarity to Cdc39p, has WD (WD-40) domain" YIL024C YIL024C 0.3 24 0.6 0.1311 0.123016141 iYIL024C 0.239994392 0.202384789 0.403274912 YIL024C -- unknown -- unknown function YJL036W SNX4 0.3 21 0.6 0.1311 0.325387675 iYJL037W YJLCdelta7 0.623346288 0.603781888 0.367837177 0.349162011 0.616661296 SNX4 -- protein targeting (putative) -- Putative nexin sorting proteinpossibly involved in proteasome function YJL051W YJL051W 0.3 17 0.6 0.1311 0.247025024 iYJL052W 0.809153517 0.69545601 0.751715882 YJL051W -- unknown -- unknown function YJL094C YJL094C 0.3 20 0.6 0.1311 0.535283191 iYJL094C 0.754117036 0.375281985 0.806624102 "YJL094C -- unknown -- Probable K+/H+-antiporter, has a role in sensitivity to NaCl" YJL168C SET2 0.3 17 0.6 0.1311 0.13699513 iYJL168C 0.362992295 0.058936487 0.330855019 SET2 -- galactose regulation -- repression of basal transcription of GAL4 YJR004C SAG1 0.3 19 0.6 0.1311 0.487819191 iYJR004C 0.171166683 0.622650641 0.487573099 SAG1 -- mating -- Alpha-agglutinin involved in cell-cell interactions during mating YKL044W YKL044W 0.3 23 0.6 0.1311 0.722394642 iYKL045W 0.261180372 0.373961442 0.583474147 YKL044W -- unknown -- unknown function YKL064W MNR2 0.3 24 0.6 0.1311 0.226685749 iYKL065C 0.221918966 0.685634477 0.270988268 "MNR2 -- manganese resistance -- Manganese resistance protein, member of metal ion transporter family of membrane transporters" YKL116C YKL116C 0.3 26 0.6 0.1311 0.319425301 0.810667096 YKL116C -- unknown -- Serine/threonine protein kinase with similarity to S pombe nim1 YKL201C MNN4 0.3 18 0.6 0.1311 0.532799736 0.569931774 MNN4 -- protein glycosylation -- transfer of mannosylphosphate to core and outer chain portions of N-linked oligosaccharides YKR035C YKR035C 0.3 19 0.6 0.1311 0.024779218 iYKR035W-A 0.317066495 0.066306364 0.22927456 YKR035C -- unknown -- unknown function YLL002W REM50 0.3 23 0.6 0.1311 0.86809507 iYLL003W 0.414559522 0.662011173 0.423461167 REM50 -- diepoxybutane and mitomycin C resistance -- resistance to mutagens such as diepoxybutane and mitomycin C YLR045C STU2 0.3 18 0.6 0.1311 0.774331483 iYLR045C 0.544230079 0.317370197 0.314210882 STU2 -- cytoskeleton -- Component of spindle pole body YLR086W SMC4 0.3 18 0.6 0.1311 0.246380941 iYLR085C 0.469862555 0.605146406 0.329465975 "SMC4 -- mitosis, chromosome condensation and segregation -- Subunit of condensin protein complex required for proper chromosome condensation and segregation, coiled-coil SMC family" YLR135W YLR135W 0.3 20 0.6 0.1311 0.204111043 iYLR134W 0.786698572 0.438242488 0.690338924 YLR135W -- unknown -- unknown function YLR171W YLR171W 0.3 19 0.6 0.1311 0.314230209 YLR171W -- unknown -- unknown function YLR363C NMD4 0.3 23 0.6 0.1311 0.796462004 iYLR363C 0.320005267 0.949148358 0.364766082 NMD4 -- unknown -- Nam7p/Upf1p-interacting protein YLR382C NAM2 0.3 21 0.6 0.1311 0.389860082 iYLR382C 0.235596557 0.555593106 0.305905826 "NAM2 -- protein synthesis -- Leucyl-tRNA synthetase, mitochondrial, dominant alleles suppress mutations in the bI4 maturase" YLR417W VPS36 0.3 20 0.6 0.1311 0.447834094 iYLR416C 0.248525178 0.787045253 0.174074373 VPS36 -- vacuolar protein targeting -- vacuolar sortingmutant has a prominent novel pre-vacuolar organelle YLR440C YLR440C 0.3 24 0.6 0.1311 0.093087259 iYLR440C 0.847703551 0.39928525 YLR440C -- unknown -- unknown function YML068W YML068W 0.3 19 0.6 0.1311 0.277923707 iYML069W 0.508412284 0.757632987 0.425438596 "YML068W -- unknown -- unknown function, has TRIAD composite zinc finger domain" YMR030W YMR030W 0.3 19 0.6 0.1311 0.220152934 iYMR029C 0.213410108 0.194108451 0.451503886 YMR030W -- unknown -- unknown function YMR064W AEP1 0.3 20 0.6 0.1311 0.743792878 iYMR063W 0.620965607 0.911672179 0.37802127 AEP1 -- protein synthesis(putative) -- accumulation of mitochondrial transcript of ATP9/OLI1 YMR097C YMR097C 0.3 22 0.6 0.1311 0.33885985 iYMR097C 0.549418085 0.372912801 0.410639413 YMR097C -- unknown -- unknown function YMR164C MSS11 0.3 22 0.6 0.1311 0.380846141 iYMR164C 0.315094738 0.462513172 0.255307263 MSS11 -- starch metabolism -- regulation of starch metabolism YMR219W ESC1 0.3 24 0.6 0.1311 0.16028182 iYMR218C 0.404592458 0.165811854 0.36326826 ESC1 -- silencing -- chromatin silencing YMR262W YMR262W 0.3 21 0.6 0.1311 0.424822773 iYMR261C 0.488454505 0.590224636 0.602694584 YMR262W -- unknown -- unknown function YNL126W SPC98 0.3 20 0.6 0.1311 0.40126997 iYNL127W 0.539400941 0.881987578 0.168185851 SPC98 -- cytoskeleton -- Spindle pole body component that interacts with gamma-tubulin YNL183C NPR1 0.3 22 0.6 0.1311 0.361752571 iYNL183C 0.646753032 0.392976856 0.70665485 NPR1 -- transport -- Serine/threonine protein kinase involved in regulating transport systems for nitrogen source nutrients YNL249C MPA43 0.3 22 0.6 0.1311 0.285052888 iYNL249C 0.767226621 0.449405583 0.592652272 MPA43 -- unknown -- leads to high levels of PDC1 expression when overproduced YNL286W CUS2 0.3 19 0.6 0.1311 0.289491795 iYNL287W 0.204856468 0.487310455 0.077472123 "CUS2 -- mRNA splicing, putative -- Suppressor of U2 snRNA mutations and homolog of human Tat-SF1 proteinhas two RNA recognition (RRM) domains" YNR058W 0.3 20 0.6 0.1311 0.284013752 iYNR057C 0.358679439 0.530051982 0.124099526 YOR113W AZF1 0.3 22 0.6 0.1311 0.391786758 iYOR112W 0.73037073 0.254108927 0.044025157 "AZF1 -- transcription (putative) -- four tandem C2H2-type zinc fingers, probable transcription factor" YOR155C YOR155C 0.3 22 0.6 0.1311 0.22092511 iYOR155C 0.200510758 0.339100065 0.285127296 YOR155C -- unknown -- unknown function YOR363C PIP2 0.3 22 0.6 0.1311 0.611569754 iYOR363C 0.407628226 0.577306015 0.301835595 PIP2 -- peroxisome proliferation -- induction of peroxisomal proteins in response to oleic acid YPL072W UBP16 0.3 19 0.6 0.1311 0.300613363 0.438009196 "UBP16 -- protein degradation, ubiquitin-mediated -- Putative ubiquitin-specific protease, ubiquitin C-terminal hydrolase" YPL124W NIP29 0.3 16 0.6 0.1311 0.053864645 iYPL125W 0.461241486 0.019304682 0.255236868 NIP29 -- nuclear protein targeting -- spindle pole body YPL156C YPL156C 0.3 20 0.6 0.1311 0.509417137 iYPL156C 0.180052884 0.353413315 0.184775262 YPL156C -- unknown -- unknown function YPR117W YPR117W 0.3 22 0.6 0.1311 0.47221921 iYPR116W 0.460434256 0.106783719 0.739106145 YPR117W -- unknown -- unknown function YAL002W VPS8 0.2 13 0.6 0.1311 0.587040792 iYAL003W 0.70193904 0.805666401 0.646528332 VPS8 -- vacuolar protein targeting -- vacuolar sorting YAL034W-A MTW1 0.2 13 0.6 0.1311 0.684033649 0.17966484 MTW1 -- unknown -- Essential kinetochore mitosis YAL037W YAL037W 0.2 15 0.6 0.1311 0.586327997 iYAL038W 0.748814745 0.705653021 0.730263158 YAL037W -- unknown -- unknown function YBL010C YBL010C 0.2 12 0.6 0.1311 0.357829723 iYBL010C 0.833076236 0.787624455 0.552046407 YBL010C -- unknown -- unknown function YCL061C YCL061C 0.2 15 0.6 0.1311 0.258202016 iYCL061C 0.074338663 0.123862898 0.073566185 YCL061C -- unknown -- unknown function YDL206W YDL206W 0.2 16 0.6 0.1311 iYDL207W 0.468347863 0.487940631 YDL206W -- unknown -- Putative membrane transporter of Ca2+ YDR065W YDR065W 0.2 15 0.6 0.1311 0.726971022 iYDR064W 0.709133022 0.531284916 0.410520774 "YDR065W -- unknown -- unknown function, induced during sporulation" YDR131C YDR131C 0.2 14 0.6 0.1311 0.456270499 iYDR131C 0.458468521 0.790605865 0.360404838 "YDR131C -- unknown -- unknown function, contains an F-box" YDR268W MSW1 0.2 15 0.6 0.1311 0.580049853 iYDR267C 0.409901626 0.948858595 0.723217303 "MSW1 -- protein synthesis -- Tryptophanyl-tRNA synthetase, mitochondrial, member of class I family of aminoacyl-tRNA synthetases" YER065C ICL1 0.2 13 0.6 0.1311 0.498689631 iYER065C YERCdelta10 0.356358921 0.836172699 0.885180804 0.173541734 0.557876906 "ICL1 -- glyoxylate cycle -- Isocitrate lyase, carries out part of glyoxylate cycle, required for gluconeogenesis" YER075C PTP3 0.2 16 0.6 0.1311 0.441767285 iYER075C itA(UGC)E 0.415036521 0.716808859 0.681724677 0.573799549 0.366902997 "PTP3 -- signaling, pheromone and high osmolarity pathways -- Protein tyrosine phosphatase (PTPase) involved in Hog1p MAP kinase high-osmolarity sensing pathway and Fus3p MAPK pheromone response pathway" YER158C YER158C 0.2 16 0.6 0.1311 0.363643865 iYER158C 0.840671768 0.694406894 0.541101357 YER158C -- unknown -- similarity to Afr1p YFR026C YFR026C 0.2 16 0.6 0.1311 0.196744799 iYFR026C YFRWdelta10 0.239995996 0.118686747 0.672736062 0.362410656 0.031770185 YFR026C -- unknown -- unknown function YGR058W YGR058W 0.2 14 0.6 0.1311 0.349650433 iYGR057C 0.257155289 0.536233041 0.242491566 YGR058W -- unknown -- unknown function YGR096W YGR096W 0.2 14 0.6 0.1311 0.417443683 iYGR095C 0.584555237 0.83575419 0.330529125 YGR096W -- unknown -- Member of mitochondrial carrier family (MCF) of membrane transporters YGR120C SEC35 0.2 14 0.6 0.1311 0.728319731 iYGR120C itN(GUU)G 0.67466354 0.599389389 0.941749919 0.56888495 0.345944128 SEC35 -- secretion -- docking ER-derived vesicles to Golgi membranes YGR179C YGR179C 0.2 16 0.6 0.1311 0.36440318 iYGR179C 0.533175843 0.301489344 0.375010083 YGR179C -- unknown -- Component of centromere/kinetochore-associated protein network YGR256W GND2 0.2 17 0.6 0.1311 0.294887178 iYGR255C itT(UGU)G2 0.739055864 0.427839586 0.64797935 0.623700455 0.496115319 "GND2 -- pentose phosphate cycle -- 6-Phosphogluconate dehydrogenase, decarboxylating, converts 6-phosphogluconate + NADP to ribulose-5-phosphate + NADPH + CO2" YIL173W VTH1 0.2 12 0.6 0.1311 0.546380813 iYIL174W-0 iYIL174W-1 0.495995259 0.572956025 0.44067113 0.110499651 0.249732576 "VTH1 -- vacuolar protein targeting -- strong similarity to Vth2p and Pep1p, potential membrane glycoprotein" YJL046W YJL046W 0.2 16 0.6 0.1311 0.485515535 iYJL047C 0.72290539 0.766879084 0.561096026 YJL046W -- unknown -- similarity to lipoate-protein ligase A YJL135W YJL135W 0.2 13 0.6 0.1311 0.936767954 iYJL136C 0.991247823 0.694396445 0.297621986 YJL135W -- unknown -- unknown function YJR106W ECM27 0.2 13 0.6 0.1311 0.223151718 iYJR105W 0.460378902 0.806124107 0.522949101 "ECM27 -- cell wall biogenesis -- Protein possibly involved in cell wall structure or biosynthesis, member of Ca2+" YJR114W YJR114W 0.2 17 0.6 0.1311 0.685745574 0.848603352 YJR114W -- unknown -- unknown function YKL055C OAR1 0.2 13 0.6 0.1311 0.763890621 iYKL055C 0.55659603 0.936465022 0.80531556 OAR1 -- respiration -- 3-Oxoacyl-[acyl-carrier-protein] reductase YKL090W YKL090W 0.2 14 0.6 0.1311 0.250790696 iYKL091C 0.413268101 0.771315641 0.507529028 YKL090W -- unknown -- unknown function YKL095W YJU2 0.2 15 0.6 0.1311 0.204099063 iYKL096W 0.587133738 0.272449336 0.452528838 YJU2 -- unknown -- unknown function YKL194C MST1 0.2 14 0.6 0.1311 0.496456862 iYKL194C 0.285466496 0.660724369 0.251563512 "MST1 -- protein synthesis -- Threonyl-tRNA synthetase, mitochondrial, member of class II family of aminoacyl-tRNA synthetases" YKL222C YKL222C 0.2 15 0.6 0.1311 0.538513684 iYKL222C 0.570414504 0.616505196 0.393081761 "YKL222C -- unknown -- similarity to transcription factors, has Zn[2]-Cys[6] fungal-type binuclear cluster domain in the N-terminal region" YKR040C YKR040C 0.2 16 0.6 0.1311 0.341173809 0.168669839 YKR040C -- unknown -- unknown functionquestionable ORF YKR076W ECM4 0.2 15 0.6 0.1311 0.512231198 iYKR075C-0 iYKR075C-1 0.076094728 0.275180986 0.776269234 0.075894296 0.344964515 ECM4 -- cell wall biogenesis -- Protein possibly involved in cell wall structure or biosynthesis YLL062C MHT1 0.2 12 0.6 0.1311 0.791542729 iYLL062C 0.193930662 0.843973359 0.391179453 MHT1 -- unknown -- Putative cobalamin-dependent homocysteine S-methyltransferase YLR042C YLR042C 0.2 11 0.6 0.1311 0.060492013 iYLR042C 0.174924241 0.094413408 0.014179826 YLR042C -- unknown -- Putative GPI-anchored unknown function YLR101C YLR101C 0.2 13 0.6 0.1311 0.539531298 0.688688366 YLR101C -- unknown -- unknown function YLR102C APC9 0.2 17 0.6 0.1311 0.339464416 iYLR102C 0.798622588 0.339360587 0.182341809 APC9 -- cell cycle -- Component of anaphase-promoting complex (APC) required for Clb2p degradation and for the metaphase-anaphase transition YLR159W YLR159W 0.2 16 0.6 0.1311 0.726396602 iYLR158C-0 iYLR158C-1 0.108462854 0.156847204 0.659523042 0.329759584 0.185838368 YLR159W -- unknown -- unknown function YLR233C EST1 0.2 15 0.6 0.1311 0.632787969 iYLR233C 0.15565763 0.814229249 0.208024492 EST1 -- telomere length regulation -- Putative component of telomerase YLR271W YLR271W 0.2 17 0.6 0.1311 0.19081043 iYLR270W 0.202124728 0.45006759 0.318144899 YLR271W -- unknown -- weak similarity to retrovirus-related protease YLR283W YLR283W 0.2 17 0.6 0.1311 0.837422413 0.959828991 YLR283W -- unknown -- unknown function YLR394W CST9 0.2 16 0.6 0.1311 0.645192465 0.532482043 "CST9 -- unknown -- synapsis, overproduction causes chromosome instability and increased mitotic recombination" YMR034C YMR034C 0.2 13 0.6 0.1311 0.157194279 iYMR034C 0.588371718 0.562761843 0.811322307 YMR034C -- unknown -- unknown function YMR117C SPC24 0.2 17 0.6 0.1311 0.720088709 iYMR117C 0.597668537 0.482374919 0.214652042 SPC24 -- cytoskeleton -- spindle pole body YMR132C 0.2 14 0.6 0.1311 0.473453469 iYMR132C 0.706884635 0.723854192 0.733509347 YMR156C YMR156C 0.2 16 0.6 0.1311 0.184960337 iYMR156C 0.218991959 0.477339873 0.194247502 YMR156C -- unknown -- Protein possibly involved in drug resistance YMR160W YMR160W 0.2 15 0.6 0.1311 0.731531978 iYMR159C 0.257179042 0.554619174 0.16935224 YMR160W -- unknown -- unknown function YMR231W PEP5 0.2 14 0.6 0.1311 0.898423707 iYMR230W 0.970207324 0.711264708 0.338599523 PEP5 -- vacuole biogenesis -- Vacuolar peripheral membrane vacuole biogenesis YNL020C ARK1 0.2 14 0.6 0.1311 0.486868572 iYNL020C 0.5752014 0.788611865 0.513857557 ARK1 -- unknown -- Serine/threonine protein kinase associated with cortical actin cytoskeleton YNL146W YNL146W 0.2 13 0.6 0.1311 0.761797572 iYNL147W 0.480204881 0.736735384 0.613791423 YNL146W -- unknown -- unknown function YNL170W YNL170W 0.2 15 0.6 0.1311 0.299139587 0.42226656 "YNL170W -- unknown -- unknown function, questionable ORF" YNL314W DAL82 0.2 15 0.6 0.1311 0.057773422 iYNL315C 0.448145189 0.147262589 0.477441703 DAL82 -- transcription -- Transcriptional activator for allantoin catabolic genes YNL332W THI12 0.2 18 0.6 0.1311 iYNL333W 0.167186225 0.076799594 "THI12 -- pyrimidine biosynthesis -- Biosynthetic enzyme involved in pyrimidine biosynthesis pathway, involved in conversion of hydroxymethyl-pyrimidine precursor to thymidineThi5p, Thi11p, Thi12p and Thi13p are nearly identical" YOL025W LAG2 0.2 12 0.6 0.1311 0.654899054 iYOL026C itS(GCU)O 0.389840928 0.640086515 0.750285141 0.139469226 0.305913632 LAG2 -- aging -- the determination of longevity YOL095C HMI1 0.2 11 0.6 0.1311 0.123981034 iYOL095C 0.516875553 0.393193632 0.293296765 HMI1 -- unknown -- Mitochondrial DNA helicase involved in maintenance of integrity of mitochondrial genome YOR011W YOR011W 0.2 17 0.6 0.1311 0.116016173 iYOR010C-0 iYOR010C-1 0.234709768 0.457545768 0.193614745 0.610308946 YOR011W -- unknown -- Member of ATP-binding cassette (ABC) superfamily of ATP-driven membrane transporters YOR275C YOR275C 0.2 17 0.6 0.1311 0.299563132 iYOR275C 0.538306938 0.761532322 0.590636057 YOR275C -- unknown -- unknown function YOR295W YOR295W 0.2 13 0.6 0.1311 0.293153737 iYOR294W 0.705789204 0.297813987 0.258833812 YOR295W -- unknown -- unknown function YOR331C YOR331C 0.2 18 0.6 0.1311 0.178317633 0.145877009 YOR331C -- unknown -- unknown function YPL036W PMA2 0.2 15 0.6 0.1311 0.256378432 iYPL037C 0.35176004 0.262842176 0.357722203 "PMA2 -- H+ homeostasis -- H+-transporting P-type ATPase of plasma membrane, expression not detected under normal growth conditions" YPL113C YPL113C 0.2 16 0.6 0.1311 0.247233324 iYPL113C 0.404403432 0.381807928 0.326216565 YPL113C -- unknown -- similarity to E. coli 2-hydroxyacid dehydrogenase (SP YPL275W YPL275W 0.2 15 0.6 0.1311 0.449613982 0.204272255 YPL275W -- unknown -- similarity to formate dehydrogenases YPR013C YPR013C 0.2 17 0.6 0.1311 0.050486374 iYPR013C-0 iYPR013C-1 0.158427087 0.508376472 0.087657106 0.249924425 0.692119825 "YPR013C -- unknown -- Putative transcription factor with similarity to mouse REX1 encoded transcription factor, has two tandem C2H2-type zinc fingers" YPR122W AXL1 0.2 15 0.6 0.1311 0.478932117 iYPR121W-0 iYPR121W-1 0.41208908 0.178521245 0.389658668 0.56795999 0.326754386 "AXL1 -- bud site selection, axial -- Protease involved in second proteolytic step of a-factor N-terminal processing" YPR153W YPR153W 0.2 16 0.6 0.1311 0.047461444 iYPR152C 0.266634288 0.084917821 0.260311268 YPR153W -- unknown -- unknown function YPR164W KIM3 0.2 15 0.6 0.1311 0.531723166 iYPR163C 0.532701959 0.354126056 0.343470194 KIM3 -- diepoxybutane and mitomycin C resistance -- resistance to mutagens such as diepoxybutane and mitomycin C YER101C AST2 0.1 10 0.6 0.1311 0.965294993 iYER101C 0.96463574 0.994360296 0.565535431 AST2 -- plasma membrane protein targeting -- similarity to Ast1p YHL036W MUP3 0.4 30 0.5 0.1011 1 0.773970934 iYHL037C 0.413917021 0.560255387 0.244494636 MUP3 -- transport -- Low affinity methionine amino acid permease YDL033C YDL033C 0.3 23 0.5 0.1011 1 0.938419487 0.373075274 YDL033C -- unknown -- similarity to H. influenzae protein HI0174 YJL049W YJL049W 0.3 27 0.5 0.1011 1 0.839898346 iYJL050W 0.935365525 0.438547486 0.396033901 YJL049W -- unknown -- unknown function YGL075C MPS2 0.1 11 0.5 0.1011 1 0.964386052 iYGL075C 0.963078365 0.769353551 0.341893781 MPS2 -- cytoskeleton -- nuclear envelope/endoplasmic reticulum required for spindle pole body assembly and normal chromosome segregation YCL052C PBN1 0.9 74 0.5 0.1011 0.440705298 iYCL052C 0.209317817 0.533274251 0.231791814 "PBN1 -- protein degradation -- Protease B, nonderepressible form, integral membrane endoplasmic reticulum required for Prb1p post-translational processing" YDR258C HSP78 0.8 58 0.5 0.1011 0.727190931 iYDR258C 0.892647908 0.648603352 0.430507381 "HSP78 -- protein folding -- Heat shock ClpB family of ATP-dependent proteases, mitochondrial" YDR326C YDR326C 0.7 47 0.5 0.1011 0.252691077 iYDR326C 0.458206123 0.592019154 0.397605746 YDR326C -- unknown -- unknown function YDR195W REF2 0.6 39 0.5 0.1011 0.592860454 iYDR194C 0.261595418 0.892732355 0.274807827 REF2 -- mRNA 3'-end processing -- mRNA 3'-end formation prior to polyadenylationmutant has significantly lower usage of weak poly(A) sites YHR114W BZZ1 0.6 36 0.5 0.1011 0.239134813 iYHR113W 0.641953947 0.241298743 0.643974461 "BZZ1 -- unknown -- similarity to SH3 domain of VAV proto-oncogene, has two SH3 domains" YLR252W YLR252W 0.6 43 0.5 0.1011 0.820389427 0.825779727 YLR252W -- unknown -- unknown function YPR055W SEC8 0.6 40 0.5 0.1011 0.627060307 iYPR054W 0.355281319 0.643791656 0.341685466 SEC8 -- secretion -- Component of exocyst complexrequired for exocytosis YBR216C YBR216C 0.4 28 0.5 0.1011 0.290801124 iYBR216C 0.241832734 0.635045423 0.590154689 YBR216C -- unknown -- unknown function YCR073C SSK22 0.4 30 0.5 0.1011 0.363274626 iYCR073C YCR073W-A 0.522376288 0.221246269 0.694652833 0.66733806 0.326576217 "SSK22 -- signaling, high osmolarity pathway -- Map kinase kinase kinase (MAPKKK) with strong similarity to Ssk2p, participates in the high-osmolarity signal transduction pathway" YDR166C SEC5 0.4 34 0.5 0.1011 0.623392377 iYDR166C 0.831309697 0.63160442 0.808874913 "SEC5 -- secretion -- Component of exocyst complex, 107 kDa, required for exocytosis" YDR458C YDR458C 0.4 35 0.5 0.1011 0.344447733 iYDR458C 0.298662164 0.533758167 0.330124249 YDR458C -- unknown -- unknown function YFL049W YFL049W 0.4 32 0.5 0.1011 0.779805451 iYFL050C 0.438503094 0.891828668 0.556936322 YFL049W -- unknown -- weak similarity to Npl6p YGL061C DUO1 0.4 29 0.5 0.1011 0.670880846 iYGL061C 0.145887885 0.739607976 0.305985634 DUO1 -- mitosis -- interacts with Dam1p and causes cell death upon overproduction YIL136W OM45 0.4 38 0.5 0.1011 0.116255076 iYIL137C 0.476723293 0.591893781 0.559429836 OM45 -- (putative) mitochondrial organization -- outer mitochondrial membrane YJL102W MEF2 0.4 31 0.5 0.1011 0.574322695 iYJL103C 0.224583493 0.806522474 0.106550634 "MEF2 -- protein synthesis -- Mitochondrial translation elongation factor, promotes GTP-dependent translocation of nascent chain from A-site to P-site of ribosome" YJR046W YJR046W 0.4 30 0.5 0.1011 0.493405009 iYJR045C 0.200441981 0.85958094 0.019168291 YJR046W -- unknown -- efficient germination YLR151C PCD1 0.4 30 0.5 0.1011 0.238999609 iYLR151C 0.090973614 0.303272147 0.038994521 "PCD1 -- unknown -- unknown function, member of nudix hydrolase family" YMR127C SAS2 0.4 34 0.5 0.1011 0.875022642 iYMR127C 0.860523065 0.681855101 0.607422187 "SAS2 -- silencing -- silencing at HMR, has a single C2H2-type zinc finger" YMR207C HFA1 0.4 33 0.5 0.1011 0.586354468 iYMR207C 0.264869031 0.248213125 0.654106117 HFA1 -- unknown -- similarity to acetyl-CoA carboxylase YMR253C YMR253C 0.4 31 0.5 0.1011 0.218719373 iYMR253C 0.143335511 0.45325482 0.24231669 "YMR253C -- unknown -- unknown function, likely membrane protein" YMR316W YMR316W 0.4 28 0.5 0.1011 0.377713972 iYMR315W 0.455611528 0.581533999 0.76217079 YMR316W -- unknown -- unknown function containing a zinc carboxypeptidase motif PS00133mRNA abundance is reduced by the drug FK506 in a calcineurin- and immunophilin-dependent manner YNR059W MNT4 0.4 30 0.5 0.1011 0.657553668 iYNR058W 0.292347588 0.7316685 0.380172622 "MNT4 -- protein glycosylation -- strong similarity to mannosyltransferases Mnn1p, Mnt2p and Mnt3p" YOR353C YOR353C 0.4 33 0.5 0.1011 0.383624314 iYOR353C 0.087524257 0.186980721 0.141475991 YOR353C -- unknown -- weak similarity to adenylate cyclases YPL008W CHL1 0.4 33 0.5 0.1011 0.571899206 iYPL009C 0.270149561 0.294413408 0.385964912 CHL1 -- mitosis -- chromosome transmission and cell cycle progression through G2/Mmember of DEAH box family YAL054C ACS1 0.3 24 0.5 0.1011 0.538307421 iYAL054C 0.675166795 0.654593853 0.594972067 ACS1 -- acetyl-CoA biosynthesis -- Acetyl-CoA synthetase YBL106C SRO77 0.3 23 0.5 0.1011 0.782830716 iYBL106C 0.688092054 0.820359764 0.620909816 SRO77 -- secretion (putative) -- functions together with Sec9p in exocytosis downstream of Rho3p GTPase YBR032W YBR032W 0.3 25 0.5 0.1011 0.817224083 iYBR031W 0.533403007 0.816999918 0.393320965 YBR032W -- unknown -- unknown function YBR081C SPT7 0.3 20 0.5 0.1011 0.246497946 iYBR081C itD(GUC)B 0.654299945 0.720530302 0.476163588 0.656408998 0.72188205 SPT7 -- chromatin structure -- Component of nucleosomal histone acetyltransferase (Spt-Ada-Gcn5-Acetyltransferase or SAGA) complex YBR194W YBR194W 0.3 21 0.5 0.1011 0.456323997 iYBR193C 0.369012599 0.551880194 0.451396648 YBR194W -- unknown -- unknown function YCL008C STP22 0.3 24 0.5 0.1011 0.248381744 iYCL008C 0.424632291 0.033983379 0.296963713 STP22 -- vacuolar protein targeting -- vacuolar targeting of temperature-sensitive plasma membrane proteins such as Ste2p and Can1p YCL060C 0.3 23 0.5 0.1011 YCR062W YCR062W 0.3 26 0.5 0.1011 0.202750786 0.090968161 YCR062W -- unknown -- unknown function YCR066W RAD18 0.3 27 0.5 0.1011 0.375908107 iYCR065W 0.378167929 0.216457023 0.141991048 "RAD18 -- DNA repair, postreplication -- Multifunctional DNA repair protein, required for post-replication repair" YCR105W YCR105W 0.3 26 0.5 0.1011 0.448493871 iYCR104W 0.250060503 0.610954263 0.209163507 YCR105W -- unknown -- similarity to bovine alcohol dehydrogenase YDL013W HEX3 0.3 21 0.5 0.1011 0.146578413 iYDL014W 0.747045491 0.406783719 0.474143955 HEX3 -- hexose metabolism (putative) -- hexose metabolism YDL159W STE7 0.3 26 0.5 0.1011 0.679560911 iYDL160C 0.403542954 0.880734815 0.308176101 "STE7 -- signaling, pheromone and pseudohyphal growth pathways -- Serine/threonine/tyrosine protein kinase of MAP kinase kinase (MAPKK or MEK) familycomponent of pheromone response, filamentous growth, and STE vegetative growth pathways" YDR103W STE5 0.3 27 0.5 0.1011 0.444916106 iYDR102C 0.334157515 0.850119713 0.295379251 "STE5 -- signaling, pheromone pathway -- Pheromone pathway scaffolding a complex with Fus3p, Ste7p, and Ste11p" YDR220C YDR220C 0.3 25 0.5 0.1011 0.596782097 0.854656784 YDR220C -- unknown -- unknown function YDR244W PEX5 0.3 23 0.5 0.1011 0.191981109 iYDR243C 0.284931027 0.540607257 0.46539961 "PEX5 -- peroxisomal protein targeting -- Peroxisomal protein (peroxin)receptor for proteins carrying peroxisomal targeting signal 1 (PTS1) sequence, has tetratricopeptide (TPR) repeats" YDR285W ZIP1 0.3 22 0.5 0.1011 0.273150871 iYDR284C 0.338133078 0.317173305 0.629967909 ZIP1 -- meiosis -- Structural synaptonemal complex central elementhas predicted coiled-coil domain YDR387C YDR387C 0.3 29 0.5 0.1011 0.753561745 iYDR387C 0.849569531 0.964964086 0.587576539 YDR387C -- unknown -- Member of hexose transporter family of major facilitator superfamily (MFS) YDR495C VPS3 0.3 27 0.5 0.1011 0.655924641 iYDR495C 0.849890135 0.71103938 0.193925234 "VPS3 -- vacuolar protein targeting -- Vacuolar sorting protein, also involved in vacuolar segregation" YER067W YER067W 0.3 25 0.5 0.1011 0.716391874 0.893967557 "YER067W -- unknown -- unknown function, transcription regulated by ploidy" YFL050C ALR2 0.3 24 0.5 0.1011 0.799660029 iYFL050C 0.438503094 0.926712089 0.556936322 "ALR2 -- aluminum resistance -- Aluminum resistance protein, member of metal ion transporter family of membrane transporters" YGR092W DBF2 0.3 27 0.5 0.1011 0.632390033 iYGR091W 0.824247789 0.771316588 0.335565056 "DBF2 -- cell cycle -- Serine/threonine protein kinase related to Dbf20p, required for events in anaphase/telophase" YGR156W YGR156W 0.3 25 0.5 0.1011 0.492266628 iYGR155W 0.546860584 0.344772546 0.560014379 YGR156W -- unknown -- unknown function YHL019C APM2 0.3 25 0.5 0.1011 0.385594477 iYHL019C 0.183002194 0.873267805 0.11380534 "APM2 -- endocytosis -- Clathrin-associated protein (AP) complex, medium subunit" YIL077C YIL077C 0.3 27 0.5 0.1011 0.287884603 iYIL077C 0.267643764 0.475668708 0.70207502 YIL077C -- unknown -- unknown function YIL095W PRK1 0.3 21 0.5 0.1011 0.290047275 iYIL096C itI(AAU)I1 0.31027442 0.508074447 0.656185156 0.225870156 0.508853151 PRK1 -- unknown -- Serine/threonine protein kinase involved in regulation of actin cytoskeleton organization YJR012C YJR012C 0.3 22 0.5 0.1011 0.330588589 iYJR012C 0.148939615 0.814614889 0.268164239 YJR012C -- unknown -- unknown function YJR115W YJR115W 0.3 28 0.5 0.1011 0.790176059 iYJR114W 0.489959641 0.459138069 0.366740722 "YJR115W -- unknown -- unknown function, has similarity to Ecm13p" YKL197C PEX1 0.3 24 0.5 0.1011 0.367349784 iYKL197C YKLWdelta1 0.478800866 0.389290646 0.720038435 0.401053238 0.461851556 "PEX1 -- peroxisome biogenesis -- Peroxisomal biogenesis protein (peroxin), member of AAA family of ATPases associated with diverse aspects of protein folding" YLL060C GTT2 0.3 26 0.5 0.1011 0.669271525 iYLL060C 0.189714749 0.799467613 0.177893057 GTT2 -- glutathione metabolism -- Glutathione transferase YLR014C PPR1 0.3 21 0.5 0.1011 0.457266988 iYLR014C 0.334087948 0.734405458 0.137210615 "PPR1 -- pyrimidine biosynthesis -- Transcription factor regulating pyrimidine pathway, contains a Zn[2]-Cys[6] fungal-type binuclear cluster domain in the N-terminal region" YLR123C YLR123C 0.3 21 0.5 0.1011 0.574983693 iYLR123C 0.61148272 0.877183788 0.78869415 YLR123C -- unknown -- similarity to class I family of aminoacyl-tRNA synthetases YLR263W RED1 0.3 25 0.5 0.1011 0.218929441 YLR262C-A iYLR262C-A 0.057400113 0.32873661 0.269168291 0.002739285 0.499621874 "RED1 -- meiosis, synapsis -- Meiosis-specific proteinassociated with lateral elements of synaptonemal complex, involved in homologous chromosome synapsis and chiasmata formation" YLR313C SPH1 0.3 25 0.5 0.1011 0.344201681 iYLR313C 0.840334743 0.665886908 0.723723481 "SPH1 -- bud site selection, bipolar -- polarized growthhas roles in shmoo formation and bud site selection" YLR434C YLR434C 0.3 25 0.5 0.1011 0.394002733 0.138414438 YLR434C -- unknown -- unknown function YML041C YML041C 0.3 22 0.5 0.1011 0.830921762 iYML041C tP(UGG)M 0.595693264 0.551479976 0.933934902 0.770222365 0.524740623 YML041C -- unknown -- unknown function YMR004W MVP1 0.3 21 0.5 0.1011 0.668944449 iYMR003W 0.157396311 0.911859491 0.144293695 "MVP1 -- vacuolar protein targeting -- sorting proteins to the vacuole, interacts genetically with Vps1p" YMR065W KAR5 0.3 23 0.5 0.1011 0.494724454 iYMR064W 0.855512274 0.90771961 0.883798883 KAR5 -- mating; nuclear fusion -- Coiled-coil membrane homotypic nuclear fusion YMR096W SNZ1 0.3 28 0.5 0.1011 0.109700725 iYMR095C 0.483400674 0.363613922 0.297606569 "SNZ1 -- unknown -- Putative pyridoxine (vitamin B6) biosynthetic enzyme, member of stationary phase-induced gene family which includes Snz2p and Snz3p" YMR163C YMR163C 0.3 24 0.5 0.1011 0.41747665 iYMR163C tV(AAC)M3 0.390321061 0.438064434 0.774853801 0.309048083 0.177148847 YMR163C -- unknown -- unknown function YMR284W YKU70 0.3 23 0.5 0.1011 0.403153809 iYMR283C YMRWdelta21 0.212746981 0.652932728 0.608539505 0.412118259 0.829589402 YKU70 -- DNA repair -- Component of DNA end-joining repair pathwayacts in complex with Yku80p YMR304W UBP15 0.3 24 0.5 0.1011 0.276592714 iYMR303C 0.394199571 0.601851852 0.352582846 "UBP15 -- protein degradation, ubiquitin-mediated -- Putative ubiquitin-specific protease, ubiquitin C-terminal hydrolase" YMR316C-A 0.3 21 0.5 0.1011 0.67135202 iYMR316C-A 0.322085099 0.45094217 0.371426251 YNL223W AUT2 0.3 22 0.5 0.1011 0.157074729 iYNL224C 0.370547093 0.303768681 0.265635919 "AUT2 -- autophagy -- mediates attachment of autophagosomes to microtubules, also required for sporulation in combination with Aut7p" YNL224C YNL224C 0.3 25 0.5 0.1011 0.22749046 iYNL224C 0.370547093 0.596328811 0.265635919 YNL224C -- unknown -- unknown function YNL311C YNL311C 0.3 23 0.5 0.1011 0.642736176 iYNL311C 0.841048373 0.26474147 0.127445842 YNL311C -- unknown -- unknown functioncontains an cyclin-associated F-box YNL337W YNL337W 0.3 24 0.5 0.1011 0.489910765 iYNL338W 0.997419309 0.027894347 YNL337W -- unknown -- unknown function YOL001W PHO80 0.3 23 0.5 0.1011 0.368764448 iYOL002C 0.217319451 0.889925611 0.704515919 "PHO80 -- cell cycle -- Cyclin that interacts with Pho85p protein kinase, regulates the phosphate pathway through phosphorylation of Pho4p" YOR102W YOR102W 0.3 24 0.5 0.1011 0.445278648 iYOR101W 0.695441274 0.136711891 0.265602554 YOR102W -- unknown -- unknown function YPL150W YPL150W 0.3 28 0.5 0.1011 0.285864876 iYPL151C 0.41996835 0.479793498 0.404469274 YPL150W -- unknown -- Serine/threonine protein kinase with unknown role YPL278C YPL278C 0.3 23 0.5 0.1011 0.272694269 0.461565339 YPL278C -- unknown -- unknown function YPR167C MET16 0.3 20 0.5 0.1011 0.050505598 iYPR167C 0.500002663 0.260893855 0.519953921 "MET16 -- sulfate assimilation -- 3'-Phosphoadenylylsulfate reductase (PAPS), part of sulfate assimilation pathway" YPR175W DPB2 0.3 26 0.5 0.1011 0.141836465 iYPR174C 0.422414977 0.176450035 0.448039878 DPB2 -- DNA replication -- DNA polymerase epsilon 80 kDa subunit YBL060W YBL060W 0.2 19 0.5 0.1011 0.908353445 iYBL061C 0.97432819 0.747725459 0.851998066 YBL060W -- unknown -- unknown function YBR047W YBR047W 0.2 12 0.5 0.1011 0.985932444 iYBR046C 0.947858619 0.889542378 0.900718276 "YBR047W -- unknown -- unknown functiontranscription induced during aerobic growth, also induced by the drug FK506 in a GCN4-dependent manner" YBR180W DTR1 0.2 18 0.5 0.1011 0.895067063 iYBR179C 0.929891866 0.845889864 0.383160415 "DTR1 -- unknown -- Member of multidrug-resistance 12-spanner family of major facilitator superfamily (MFS-MDR), dityrosine transporter" YCL006C YCL006C 0.2 17 0.5 0.1011 0.728379524 0.646671604 YCL006C -- unknown -- unknown function YCR027C RSG1 0.2 21 0.5 0.1011 0.316295876 iYCR027C itQ(UUG)C 0.696005162 0.625285854 0.461563281 0.508217854 0.388550021 "RSG1 -- unknown -- regulation of arginine and lysine uptake, member of Rheb family in the Ras superfamily of G proteins" YDL091C YDL091C 0.2 22 0.5 0.1011 0.370673682 iYDL091C 0.714481435 0.672743406 0.327901912 YDL091C -- unknown -- unknown function YDL107W MSS2 0.2 17 0.5 0.1011 0.629724335 iYDL108W 0.517681835 0.610384267 0.743312923 "MSS2 -- mRNA splicing, COX1 mRNA -- mitochondrial expression of Cox2psimilar to Drosophila kinesin light chain protein" YDL127W PCL2 0.2 14 0.5 0.1011 0.308809034 iYDL128W 0.560670826 0.443736388 0.653466487 "PCL2 -- cell cycle -- Cyclin, found partly in association with Pho85p" YDR192C NUP42 0.2 18 0.5 0.1011 0.873559327 0.969816225 NUP42 -- nuclear protein targeting -- Nuclear pore protein (nucleoporin)has similarity to Nup159p YDR380W YDR380W 0.2 17 0.5 0.1011 0.811106828 iYDR379W 0.161945788 0.988649669 0.239929101 YDR380W -- unknown -- Putative indole-3-pyruvate decarboxylase YER104W RTT105 0.2 18 0.5 0.1011 0.547144282 iYER103W 0.597409027 0.909734222 0.414684757 RTT105 -- transposition (putative) -- inhibits transposable element Ty1 transposition YFR045W YFR045W 0.2 19 0.5 0.1011 0.718615302 iYFR044C 0.224623604 0.961930483 0.119395712 YFR045W -- unknown -- Member of mitochondrial carrier family (MCF) family of membrane transporters YGL041C YGL041C 0.2 15 0.5 0.1011 0.471409125 iYGL041C 0.430951174 0.38565782 0.442030774 YGL041C -- unknown -- unknown function YGL042C YGL042C 0.2 17 0.5 0.1011 0.401301471 iYGL042C 0.166935789 0.396333221 0.063563765 YGL042C -- unknown -- similarity to rat Na+/Ca2+ exchanger NCX2 PIR YGL163C RAD54 0.2 18 0.5 0.1011 0.350240903 iYGL163C-0 iYGL163C-1 0.458805441 0.041964788 0.670949721 0.576458266 0.29260265 "RAD54 -- DNA repair -- DNA-dependent ATPase of Snf2p family, required for recombination and repair of X-ray damage" YGL194C HOS2 0.2 15 0.5 0.1011 0.675557787 iYGL194C 0.718821872 0.977682888 0.822622212 "HOS2 -- chromatin structure -- similarity to Hda1p, Rpd3p, Hos1p, and Hos3p" YGL199C YGL199C 0.2 20 0.5 0.1011 0.592631574 0.836951317 YGL199C -- unknown -- unknown function YGR134W YGR134W 0.2 17 0.5 0.1011 0.415941869 iYGR133W 0.452685583 0.864002578 0.639509559 YGR134W -- unknown -- unknown function YGR150C YGR150C 0.2 13 0.5 0.1011 0.663155297 iYGR150C YGRWdelta26 0.409531939 0.205168115 0.535899935 0.407485637 0.136803094 YGR150C -- unknown -- similarity to Yjl083p YGR219W YGR219W 0.2 21 0.5 0.1011 0.30333822 iYGR218W 0.424931167 0.27877095 0.401720305 YGR219W -- unknown -- unknown function YGR239C PEX21 0.2 15 0.5 0.1011 0.343938315 iYGR239C 0.632101138 0.412561146 0.725910409 "PEX21 -- peroxisome biogenesis (putative) -- Peroxisomal biogenesis protein (peroxin), involved with Pex18p in Pex7p-mediated peroxisomal protein targeting" YGR278W YGR278W 0.2 14 0.5 0.1011 0.201427319 iYGR277C 0.542159261 0.283981472 0.131524342 "YGR278W -- unknown -- unknown function, has similarity to S. pombe Spbc13e7.01p and C. elegans LET-858" YHR016C YSC84 0.2 24.5 0.5 0.1011 0.313255828 iYHR016C 0.384188174 0.65852053 0.241526904 "YSC84 -- unknown -- unknown function, has an SH3 domain" YHR067W YHR067W 0.2 18 0.5 0.1011 0.544420749 iYHR066W 0.214548284 0.897878519 0.107247406 YHR067W -- unknown -- unknown function YHR172W SPC97 0.2 20 0.5 0.1011 0.722832231 iYHR171W 0.102335838 0.654668795 0.721688648 SPC97 -- cytoskeleton -- Spindle pole body component that plays a role in organization of nuclear and cytoplasmic microtubules YIL150C DNA43 0.2 13 0.5 0.1011 0.596223094 iYIL150C 0.635072589 0.673987052 0.737759135 DNA43 -- DNA replication -- S-phase initiation or completion YIR025W YIR025W 0.2 15 0.5 0.1011 0.083671706 iYIR024C 0.066132427 0.241439553 0.112387508 YIR025W -- unknown -- unknown function YJL099W CHS6 0.2 18 0.5 0.1011 0.213870184 iYJL100W 0.588625271 0.654320988 0.750960867 "CHS6 -- cell wall biogenesis -- chitin synthase Chs3p activityhas tetratricopeptide (TPR) repeats , mutants are resistant to calcofluor white" YJL119C YJL119C 0.2 18 0.5 0.1011 0.557306917 0.656852464 YJL119C -- unknown -- unknown functionquestionable ORF YJL206C YJL206C 0.2 16 0.5 0.1011 0.358871292 iYJL206C 0.30973344 0.488424619 0.559454191 "YJL206C -- unknown -- weak similarity to Put3p and other transcription factors, has a Zn[2]-Cys[6] fungal-type binuclear cluster domain in the N-terminal region" YJL221C FSP2 0.2 19 0.5 0.1011 0.398259465 0.906943336 "FSP2 -- unknown -- similarity to alpha-D-glucosidase (maltase), identical to Yil172p and nearly identical to Ygr287p" YJR089W BIR1 0.2 22 0.5 0.1011 0.338952239 iYJR088C 0.19652921 0.503126056 0.41833807 "BIR1 -- unknown -- chromosome segregation, contains a BIR domain that is common to inhibitors of apoptosis" YKL092C BUD2 0.2 17 0.5 0.1011 0.368598137 iYKL092C 0.540359792 0.779158545 0.4432524 BUD2 -- bud site selection -- GTPase-activating protein for Rsr1p/Bud1p involved in bud site selection YKL136W YKL136W 0.2 16 0.5 0.1011 0.288576286 iYKL137W 0.587299991 0.326869322 0.37657638 YKL136W -- unknown -- unknown function YKR073C YKR073C 0.2 16 0.5 0.1011 0.533499449 iYKR073C itK(UUU)K 0.516684506 0.841543635 0.73025856 0.450236566 0.62808642 YKR073C -- unknown -- unknown function YLL007C YLL007C 0.2 17 0.5 0.1011 0.367393438 iYLL007C 0.189643907 0.396609891 0.223064645 YLL007C -- unknown -- unknown function YLR092W SUL2 0.2 16 0.5 0.1011 0.164859333 iYLR091W 0.339249788 0.347134871 0.208014482 "SUL2 -- transport -- High-affinity sulfate transporter, member of sulfate permease family of membrane transporters" YLR161W YLR161W 0.2 18 0.5 0.1011 0.825735593 iYLR160C-0 iYLR160C-1 0.183422373 0.256546143 0.476919279 YLR161W -- unknown -- unknown function YLR273C PIG1 0.2 18 0.5 0.1011 0.390423539 iYLR273C 0.37736875 0.669516819 0.552456184 PIG1 -- glucose repression -- interacts with Gsy2ppossible regulatory subunit for the PP1 family protein phosphatase Glc7p YLR318W EST2 0.2 15 0.5 0.1011 0.529919321 iYLR317W 0.520753354 0.520873944 0.739603639 "EST2 -- telomere length regulation -- Catalytic component of telomerase, predicted reverse transcriptase" YLR423C YLR423C 0.2 14 0.5 0.1011 0.16406407 iYLR423C 0.307889804 0.429342572 0.163954238 YLR423C -- unknown -- weak similarity to human cytokeratin 9 (SP YLR424W YLR424W 0.2 12 0.5 0.1011 0.259592376 iYLR423C 0.307889804 0.567883335 0.163954238 YLR424W -- unknown -- similarity to retrovirus-related protease YMR036C MIH1 0.2 18 0.5 0.1011 0.222050824 iYMR036C 0.336749541 0.48189078 0.648544003 "MIH1 -- cell cycle -- M-phase inducing protein tyrosine phosphatase (PTPase), dephosphorylates Cdc28p to activate kinase activity" YMR075W YMR075W 0.2 15 0.5 0.1011 0.259436606 iYMR074C 0.238841436 0.570906433 0.395061728 "YMR075W -- unknown -- unknown function, contains a PHD domain" YMR165C SMP2 0.2 18 0.5 0.1011 0.494569015 iYMR165C 0.305401599 0.482132774 0.121867518 SMP2 -- respiration; plasmid maintenance -- plasmid maintenance and respiration YMR167W MLH1 0.2 19 0.5 0.1011 0.216681776 iYMR166C 0.155728169 0.416037694 0.08697441 MLH1 -- DNA repair -- Mismatch repair protein and homolog of E. coli MutL YMR271C URA10 0.2 15 0.5 0.1011 0.514437636 iYMR271C itQ(CUG)M 0.654400037 0.673963411 0.893455706 0.749616843 0.518924626 "URA10 -- pyrimidine biosynthesis -- Orotate phosphoribosyltransferase 2, fifth step in pyrimidine biosynthesis pathway" YMR287C MSU1 0.2 15 0.5 0.1011 0.270731021 iYMR287C 0.391978566 0.702378014 0.60745614 MSU1 -- mitochondrial biogenesis -- Component of a mitochondrial 3'-5' exonuclease complex that is essential for mitochondrial biogenesis YNL144C YNL144C 0.2 14 0.5 0.1011 0.277704667 iYNL144C-0 iYNL144C-1 0.908854378 0.91684633 0.18714205 0.415565582 0.693100827 YNL144C -- unknown -- unknown function YNL237W YTP1 0.2 15 0.5 0.1011 0.1285122 iYNL238W 0.340130945 0.382512229 0.333495776 YTP1 -- unknown -- similarity to mitochondrial electron transport proteins YNL242W SPO72 0.2 18 0.5 0.1011 0.432620059 iYNL243W 0.559179617 0.418574136 0.367266274 SPO72 -- unknown -- unknown function YNR047W YNR047W 0.2 20 0.5 0.1011 0.669939764 iYNR046W 0.232475733 0.271929825 YNR047W -- unknown -- Serine/threonine protein kinase of unknown function YOL017W YOL017W 0.2 17 0.5 0.1011 0.3198402 iYOL018C 0.296999531 0.313328013 0.310505962 YOL017W -- unknown -- unknown function YOL067C RTG1 0.2 16 0.5 0.1011 0.082170275 iYOL067C 0.318196668 0.369114126 0.160286218 "RTG1 -- organelle communication -- Basic helix-loop-helix (bHLH) transcription factor involved in inter-organelle communication between mitochondria, peroxisomes, and nucleus" YOL141W PPM2 0.2 15 0.5 0.1011 0.579467494 iYOL142W 0.173242337 0.889622946 0.070737995 "PPM2 -- unknown -- Putative leucine carboxyl methyltransferase, has similarity to human LCMT" YOR003W YSP3 0.2 12 0.5 0.1011 0.151745193 iYOR002W 0.429843189 0.410018891 0.74197364 YSP3 -- protein degradation -- Subtilisin-like protease III YOR037W CYC2 0.2 22 0.5 0.1011 0.216180285 iYOR036W 0.201833628 0.634637373 0.057524976 "CYC2 -- mitochondrial protein targeting -- Cytochrome-c mitochondrial import factor, affects import of Cyc1p and Cyc7p with Cyc1p affected more" YOR193W YOR193W 0.2 19 0.5 0.1011 0.390050399 iYOR192C-0 iYOR192C-1 0.437448356 0.390150651 0.443307342 0.777668065 0.297666599 YOR193W -- unknown -- unknown function YOR242C SSP2 0.2 16 0.5 0.1011 0.216669848 iYOR242C 0.297533116 0.414554906 0.597953216 SSP2 -- sporulation -- Sporulation-specific protein YOR308C SNU66 0.2 20 0.5 0.1011 0.013808677 iYOR308C 0.653704182 0.020488768 0.250243665 SNU66 -- mRNA splicing (putative) -- Component of U4/U6.U5 snRNP YOR350C MNE1 0.2 16 0.5 0.1011 0.453274893 iYOR350C 0.634066624 0.659353069 0.518031189 MNE1 -- unknown -- unknown function YOR368W RAD17 0.2 18 0.5 0.1011 0.889857034 iYOR367W 0.813103391 0.588747007 0.542458101 "RAD17 -- cell cycle, checkpoint -- Checkpoint DNA damage-induced arrest in G2 at the RAD9 checkpoint" YOR389W YOR389W 0.2 15 0.5 0.1011 0.256926879 iYOR388C 0.658255661 0.520932484 0.341049383 YOR389W -- unknown -- unknown function YPL045W VPS16 0.2 14 0.5 0.1011 0.424980336 iYPL046C 0.156003561 0.573423783 0.177263289 "VPS16 -- vacuolar protein targeting -- Vacuolar sorting protein, mutant form exhibits pleiotropic defects in vacuolar morphology and vacuolar protein targeting" YPL142C YPL142C 0.2 18 0.5 0.1011 0.853384341 iYPL142C 0.675514538 0.817522711 0.401342179 YPL142C -- unknown -- unknown function YPL219W PCL8 0.2 16 0.5 0.1011 0.555573892 iYPL220W 0.813039216 0.445476173 0.415485015 "PCL8 -- cell cycle -- Cyclin that associates with Pho85p, involved in control of glycogen accumulation" YPR093C YPR093C 0.2 17 0.5 0.1011 0.082985785 iYPR093C 0.517750232 0.193854749 0.459226771 YPR093C -- unknown -- unknown function YPR179C PLO1 0.2 13 0.5 0.1011 0.094016769 iYPR179C 0.513546105 0.056611436 0.557536645 PLO1 -- unknown -- weak similarity to C-terminal region of Nip80p YDR488C PAC11 0.1 10 0.5 0.1011 0.681986021 iYDR488C 0.33020313 0.762316562 0.23336291 "PAC11 -- unknown -- Protein required in the absence of Cin8p, member of WD (WD-40) repeat family" YGL081W YGL081W 0.1 12 0.5 0.1011 0.573410071 iYGL082W 0.465012309 0.807029402 0.626576217 YGL081W -- unknown -- unknown function YML037C YML037C 0.1 10 0.5 0.1011 0.249754982 iYML037C 0.226989422 0.234183536 0.405826018 YML037C -- unknown -- unknown function YOR012W YOR012W 0.1 12 0.5 0.1011 0.444733896 iYOR011W tT(AGU)O2 0.409298994 0.787733745 0.313109162 0.11147633 0.532402235 YOR012W -- unknown -- unknown function YCL024W KCC4 0.3 34 0.4 0.0669 1 0.512738522 0.362968875 KCC4 -- unknown -- Serine/threonine protein kinase involved in septin organization and cell cycle control YDR409W YDR409W 0.1 17 0.4 0.0669 1 0.552450267 iYDR408C 0.9351431 0.41837232 0.625312576 YDR409W -- unknown -- similarity to Nfi1p YHR104W GRE3 1 104 0.4 0.0669 0.60733763 iYHR103W 0.558928282 0.79769299 0.334178224 GRE3 -- unknown -- Aldose reductase with NADPH specificityinduced by osmotic stress YPR101W SNT309 0.9 75 0.4 0.0669 0.825252668 iYPR100W 0.377836455 0.669313957 0.197205978 "SNT309 -- mRNA splicing -- mRNA splicing factor, component of Prp19p-associated complex and the spliceosome" YCL038C YCL038C 0.8 61 0.4 0.0669 0.315237117 iYCL038C 0.821969829 0.450199521 0.582640962 YCL038C -- unknown -- unknown function YLR270W YLR270W 0.8 79 0.4 0.0669 0.832589655 0.884144376 YLR270W -- unknown -- unknown function YLR178C TFS1 0.7 69 0.4 0.0669 0.25147887 iYLR178C 0.550122845 0.421608121 0.755147646 "TFS1 -- cell cycle -- CDC25-dependent nutrient- and ammonia-response cell cycle regulator, suppressor of CDC25 mutations" YBR214W SDS24 0.6 56 0.4 0.0669 0.381643498 iYBR213W 0.347921661 0.546503186 0.275346401 SDS24 -- unknown -- Nuclear similarity to S. pombe sds23/moc1 protein YDR059C UBC5 0.6 69.5 0.4 0.0669 0.744601181 iYDR059C 0.641611062 0.858739026 0.794094174 "UBC5 -- protein degradation, ubiquitin-mediated -- Ubiquitin-conjugating enzyme that with Ubc4p is responsible for most of ubiquitin-dependent protein degradation of short-lived and abnormal proteins" YDR150W NUM1 0.6 48 0.4 0.0669 0.114632972 0.077655486 "NUM1 -- mitosis, nuclear migration -- Nuclear migration protein, controls interaction of bud-neck cytoskeleton with G2 nucleus" YDR151C CTH1 0.6 52 0.4 0.0669 iYDR151C 0.48923339 0.750725105 CTH1 -- unknown -- inducible CCCH zinc finger family YLR260W LCB5 0.6 54 0.4 0.0669 0.239869081 iYLR259C 0.308902701 0.569207219 0.616679968 "LCB5 -- sphingolipid metabolism -- Long chain base kinase, involved in sphingolipid metabolism" YBL094C YBL094C 0.4 47 0.4 0.0669 0.944696043 iYBL094C 0.943411545 0.869883041 0.7197037 "YBL094C -- unknown -- weak similarity to Neurospora crassa chitin synthase, may not be an expressed ORF" YDL175C YDL175C 0.4 37 0.4 0.0669 0.221530343 iYDL175C 0.23511537 0.462437258 0.158419792 "YDL175C -- unknown -- unknown function, contains a RING-type zinc finger domain" YER171W RAD3 0.4 39 0.4 0.0669 0.823087053 iYER170W 0.531811559 0.842219892 0.580896686 "RAD3 -- transcription; DNA repair -- DNA helicase component of RNA polymerase II transcription initiation factor TFIIH (factor b), also a component of nucleotide excision repairosome" YFL033C RIM15 0.4 39 0.4 0.0669 0.597401263 iYFL033C 0.5663068 0.596512683 RIM15 -- meiosis -- Serine/threonine protein kinasepositive regulator of IME2 expression and of sporulation YFR030W MET10 0.4 42 0.4 0.0669 0.622028185 iYFR029W 0.275428589 0.961603614 0.333576998 "MET10 -- sulfate assimilation -- Assimilatory sulfite reductase subunit, flavin-binding (alpha) subunit, part of sulfate assimilation pathway" YJL035C TAD2 0.4 46 0.4 0.0669 0.314241366 iYJL035C 0.60603853 0.598535341 0.915531097 TAD2 -- tRNA processing -- Subunit tRNA[Ala]-specific adenosine deaminase YLR136C TIS11 0.4 42 0.4 0.0669 0.338607467 iYLR136C 0.181839503 0.399818975 0.158034369 TIS11 -- unknown -- inducible CCCH zinc finger family YLR450W HMG2 0.4 40 0.4 0.0669 0.358213972 iYLR449W 0.68454356 0.486061876 0.722619818 "HMG2 -- sterol metabolism -- 3-Hydroxy-3-methylglutaryl-coenzyme A reductase 2, rate limiting enzyme for sterol biosynthesis, converts HMG-CoA to mevalonate" YMK1 0.4 43 0.4 0.0669 YMR198W CIK1 0.4 33 0.4 0.0669 0.304868664 iYMR197C 0.156168865 0.403110343 0.628700492 CIK1 -- cytoskeleton -- Coiled-coil spindle pole body involved in spindle formation and the congression (nuclear migration) step of karyogamy YOR227W YOR227W 0.4 36 0.4 0.0669 0.131079706 iYOR226C 0.085332463 0.220995811 0.085670835 YOR227W -- unknown -- unknown function YBR156C SLI15 0.3 27 0.4 0.0669 0.325167154 iYBR156C 0.467489384 0.557283274 0.371101365 "SLI15 -- mitosis, chromosome segregation -- Mitotic spindle proper chromosome segregation" YBR203W YBR203W 0.3 35 0.4 0.0669 0.34830824 iYBR202W 0.550861494 0.538125264 0.333770091 "YBR203W -- unknown -- unknown function, contains an F-box domain" YBR295W PCA1 0.3 27 0.4 0.0669 0.41674936 iYBR294W 0.861421402 0.364884278 0.558216078 PCA1 -- transport -- P-type copper-transporting ATPase YCL016C YCL016C 0.3 25 0.4 0.0669 0.439597885 iYCL016C 0.276130391 0.905746209 0.710935571 "YCL016C -- unknown -- unknown function, required for resistance to certain drugs" YCR092C MSH3 0.3 29 0.4 0.0669 0.287437267 iYCR092C 0.11949804 0.735786225 0.026118099 "MSH3 -- DNA repair, mismatch -- Component of DNA mismatch binding factor along with Msh2pinvolved in mismatch repair involving microsatellite (short repeat) sequences" YDL069C CBS1 0.3 29 0.4 0.0669 0.39456548 0.351589797 CBS1 -- protein synthesis -- Translational activator of COB mRNA YDL170W UGA3 0.3 30 0.4 0.0669 0.762806525 iYDL171C 0.595067293 0.879244979 0.666419814 "UGA3 -- transcription -- Transcriptional activator for 4-aminobutyric acid (GABA) catabolic genes, including UGA4, UGA1, and UGS2" YDL244W THI13 0.3 26 0.4 0.0669 0.393648404 iYDL245C-0 iYDL245C-1 0.49437682 0.345011897 0.818825087 0.764179826 0.703241157 "THI13 -- unknown -- Biosynthetic enzyme involved in pyrimidine biosynthesis pathway, involved in conversion of hydroxymethyl-pyrimidine precursor to thymidineThi5p, Thi11p, Thi12p and Thi13p are nearly identical" YDR219C YDR219C 0.3 31 0.4 0.0669 0.401833529 iYDR219C 0.520040707 0.529402275 0.476376696 "YDR219C -- unknown -- unknown function, contains an F-box" YER084W YER084W 0.3 29 0.4 0.0669 0.199416465 0.061078622 YER084W -- unknown -- unknown function YGL072C YGL072C 0.3 26 0.4 0.0669 0.991736903 iYGL072C 0.975433755 0.329597141 0.400096681 YGL072C -- unknown -- unknown function YGL131C YGL131C 0.3 30 0.4 0.0669 0.591704444 iYGL131C 0.376959425 0.655227454 0.162011173 YGL131C -- unknown -- unknown function YGL250W YGL250W 0.3 25 0.4 0.0669 0.315219329 iYGL251C 0.05512107 0.783248178 0.17047087 YGL250W -- unknown -- unknown function YGR042W YGR042W 0.3 30 0.4 0.0669 0.129718825 iYGR041W 0.324753116 0.333439745 "YGR042W -- unknown -- unknown function, may be involved in signal transduction" YHR211W FLO5 0.3 33 0.4 0.0669 0.407504427 iYHR210C-0 iYHR210C-A 0.580642249 0.736198802 0.657063197 0.885272317 0.664565044 "FLO5 -- flocculation -- Flocculin, has similarity to flocculation protein Flo1p" YJL005W CYR1 0.3 34 0.4 0.0669 0.435745438 iYJL006C itL(UAA)J 0.600795283 0.611327473 0.257302724 0.398725498 0.496256068 "CYR1 -- cell cycle -- Adenylate cyclase, generates cAMP in response to ras activation" YJL060W YJL060W 0.3 33 0.4 0.0669 0.744221635 iYJL061W 0.375263073 0.873213125 0.777209227 YJL060W -- unknown -- unknown functionhas similarity to kynurenine aminotransferase YJL132W YJL132W 0.3 29 0.4 0.0669 0.703249073 iYJL133W 0.599637604 0.637057397 0.522155978 YJL132W -- unknown -- similarity to phospholipase D YKL083W YKL083W 0.3 25 0.4 0.0669 0.353653061 iYKL084W 0.376016063 0.179157932 0.054463422 YKL083W -- unknown -- unknown functionquestionable ORF YLR339C YLR339C 0.3 29 0.4 0.0669 0.966514211 0.9426307 YLR339C -- unknown -- unknown function YLR425W TUS1 0.3 29 0.4 0.0669 0.210402256 iYLR424W itN(GUU)L 0.503208452 0.544006085 0.235056869 0.69859161 0.184748428 TUS1 -- unknown -- similarity to Rom1p and Rom2p GDP-GTP exchange factors YNL293W MSB3 0.3 28 0.4 0.0669 0.42028892 iYNL294C 0.319203437 0.536328479 0.543841252 "MSB3 -- unknown -- GTPase-activating protein for Sec4p, multicopy suppressor of bud emergence mutant" YNR010W CSE2 0.3 33 0.4 0.0669 0.333562294 iYNR009W 0.060221524 0.666027091 0.045019735 "CSE2 -- mitosis, chromosome segregation -- Component of RNA polymerase II mediator (SRB) subcomplex" YNR068C YNR068C 0.3 33 0.4 0.0669 0.633706983 iYNR068C 0.614045487 0.569932324 0.406219787 "YNR068C -- unknown -- similarity to Bul1p ubiquitin ligase binding protein, may be a pseudogene or separated from YNR069C by sequencing errors" YOL065C INP54 0.3 30 0.4 0.0669 0.191786299 iYOL065C 0.385559619 0.650584795 0.215234102 INP54 -- unknown -- Inositol polyphosphate 5-phosphatase YOR152C YOR152C 0.3 28 0.4 0.0669 0.246524441 iYOR152C-0 iYOR152C-1 0.13747787 0.033714808 0.615874808 0.226815642 0.060834958 YOR152C -- unknown -- unknown function YPL282C YPL282C 0.3 34 0.4 0.0669 0.945489576 iYPL282C 0.922885072 0.355467786 0.145969673 YPL282C -- unknown -- Member of seripauperin (PAU) family (YPL282C and YOR394W code for identical proteins) YPR042C YPR042C 0.3 33 0.4 0.0669 0.701032657 iYPR042C 0.944816701 0.368236233 0.584206848 YPR042C -- unknown -- similarity to Jsn1p YPR047W MSF1 0.3 29 0.4 0.0669 0.139838911 iYPR046W 0.265567914 0.318036712 0.076873437 "MSF1 -- protein synthesis -- Phenylalanyl-tRNA synthetase, mitochondrial, homologous to bacterial alpha subunit but active as a single chain" YAL024C LTE1 0.2 15 0.4 0.0669 0.583491772 iYAL024C 0.045384729 0.44626563 0.170665765 LTE1 -- cell cycle -- GDP/GTP exchange factor YAL062W GDH3 0.2 18 0.4 0.0669 0.56169787 iYAL063C-0 iYAL063C-1 0.479264792 0.542969692 0.755360624 0.540702314 0.851875499 "GDH3 -- glutamate biosynthesis -- Glutamate dehydrogenase (NADP+), combines ammonia and alpha-ketoglutarate to form glutamate" YAR019C CDC15 0.2 24 0.4 0.0669 0.63661618 iYAR019C-0 iYAR019C-1 0.532605549 0.763220563 0.598047915 0.79491553 0.449000967 CDC15 -- cell cycle -- MAP kinase kinase kinase essential for late nuclear division YAR035W YAT1 0.2 25 0.4 0.0669 0.630226821 iYAR033W iYARWdelta7 0.194185541 0.527953792 0.63462778 0.613889828 0.025570703 "YAT1 -- fatty acid transport -- Outer carnitine acetyltransferase, mitochondrial" YAR050W FLO1 0.2 20 0.4 0.0669 0.588212658 iYAR047C-0 iYAR047C-1 0.466145356 0.496632856 0.423001949 0.737037857 0.808936065 "FLO1 -- flocculation -- Flocculin, cell wall flocculation" YBL019W APN2 0.2 25 0.4 0.0669 0.458513161 iYBL020W 0.72724519 0.719384467 0.526017558 "APN2 -- DNA repair -- AP endonuclease, DNA apurinic- or apyrimidinic-site lyase" YBL066C SEF1 0.2 18 0.4 0.0669 0.300664175 0.131027254 "SEF1 -- transcription -- similarity to transcription factors, has Zn[2]-Cys[6] fungal-type binuclear cluster domain in the N-terminal region" YBR114W RAD16 0.2 22 0.4 0.0669 0.461684889 iYBR113W 0.511732474 0.702131161 0.39169992 "RAD16 -- DNA repair, nucleotide excision -- Nucleotide excision repair G2 repair of inactive genes, has DNA helicase domain of Snf2p family" YBR239C YBR239C 0.2 24 0.4 0.0669 0.044856949 iYBR239C 0.311270864 0.12191358 0.440782123 "YBR239C -- unknown -- similarity to transcription factors, has Zn[2]-Cys[6] fungal-type binuclear cluster domain in the N-terminal region" YCL063W 0.2 21 0.4 0.0669 0.27332235 iYCL064C 0.377781853 0.145922401 0.186380534 YCR054C CTR86 0.2 23 0.4 0.0669 0.515698201 iYCR054C 0.392414741 0.587475634 0.543937806 CTR86 -- unknown -- unknown function YDL041W YDL041W 0.2 24 0.4 0.0669 0.250706621 0.223815662 YDL041W -- unknown -- unknown function YDL211C YDL211C 0.2 20 0.4 0.0669 iYDL211C-0 iYDL211C-1 0.388588705 0.595982785 0.621331237 0.720562824 YDL211C -- unknown -- unknown function YDR076W RAD55 0.2 18 0.4 0.0669 0.503103535 iYDR075W 0.709342214 0.511851061 0.715074724 RAD55 -- DNA repair and recombination -- Component of recombinosome complex involved in meiotic recombination and recombinational repairwith Rad57p promotes DNA strand exchange by Rad51p recombinase YDR104C SPO71 0.2 22 0.4 0.0669 0.280916699 iYDR104C 0.196440158 0.532951982 0.141556558 SPO71 -- unknown -- spore wall formation YDR179C YDR179C 0.2 19 0.4 0.0669 0.189186088 iYDR179C 0.313181006 0.632686932 0.627699001 YDR179C -- unknown -- unknown function YDR247W YDR247W 0.2 22 0.4 0.0669 0.756929024 iYDR246W 0.134869795 0.95878035 0.073586745 YDR247W -- unknown -- Serine/threonine protein kinase with similarity to S. pombe RAN1 negative regulator of sexual conjugation and meiosis YDR259C YAP6 0.2 23 0.4 0.0669 0.825387893 iYDR259C 0.687071562 0.671133853 0.469948018 "YAP6 -- salt tolerance -- Transcription factor of basic leucine zipper (bZIP) family, involved in salt tolerance, member of a fungal-specific family of bZIP proteins" YDR327W YDR327W 0.2 21 0.4 0.0669 0.314143266 iYDR326C 0.458206123 0.814531391 0.397605746 YDR327W -- unknown -- unknown function YDR332W YDR332W 0.2 23 0.4 0.0669 0.702432322 iYDR331W 0.621921581 0.933432074 0.408630328 YDR332W -- unknown -- Member of DEAD-box family of predicted RNA helicases YDR386W MUS81 0.2 20 0.4 0.0669 0.631409629 iYDR385W 0.672996758 0.762326781 0.329928172 MUS81 -- DNA repair (putative) -- repair of DNA damagefound in a complex with Rad54p YDR421W YDR421W 0.2 21 0.4 0.0669 0.514314186 iYDR420W 0.525950985 0.861053472 0.677225471 "YDR421W -- unknown -- Positive transcription regulator of ARO9 and ARO10/YDR380W, member of Zn2Cys6 transcription factor family" YDR439W LRS4 0.2 23 0.4 0.0669 0.703982516 iYDR438W 0.468617325 0.860054786 0.41763367 LRS4 -- silencing (rDNA) (putative) -- rDNA silencing YEL062W NPR2 0.2 19 0.4 0.0669 0.292268339 iYEL063C 0.605509133 0.413481435 0.527231711 NPR2 -- nitrogen transport -- Nitrogen permease regulator YER040W GLN3 0.2 25 0.4 0.0669 0.402124516 YER039C-A iYER039C-A 0.37221044 0.108101094 0.547776345 0.23852545 0.152585333 GLN3 -- nitrogen catabolite repression -- GATA-type zinc finger transcription factor for positive nitrogen regulation YER139C YER139C 0.2 16 0.4 0.0669 0.662295613 iYER139C 0.121181881 0.96977638 0.252616734 YER139C -- unknown -- growth at high temperature YER185W YER185W 0.2 25 0.4 0.0669 0.556395209 iYER184C 0.497586884 0.6633097 0.695211492 YER185W -- unknown -- similarity to Rtm1p YFL042C YFL042C 0.2 23 0.4 0.0669 0.457599711 iYFL042C 0.115843439 0.773977575 0.283133016 "YFL042C -- unknown -- unknown function, has similarity to Yhr080p" YFR022W YFR022W 0.2 23 0.4 0.0669 0.610828607 iYFR021W 0.187951911 0.669546614 0.352420403 YFR022W -- unknown -- similarity to Rod1p YGL096W YGL096W 0.2 18 0.4 0.0669 0.304449395 iYGL097W-0 iYGL097W-1 0.608134597 0.298387625 0.366339027 0.385594586 0.386777128 "YGL096W -- unknown -- weak similarity to Cup9p, contains a homeodomain" YGL098W YGL098W 0.2 24 0.4 0.0669 0.066047028 iYGL099W 0.668098071 0.082085475 0.573586745 YGL098W -- unknown -- unknown function YGL144C YGL144C 0.2 15 0.4 0.0669 0.460288058 iYGL144C 0.480770823 0.870452529 0.257096992 "YGL144C -- unknown -- unknown function, has strong similarity to Ydl109p and Ydr444p" YGL156W AMS1 0.2 27 0.4 0.0669 0.297900561 iYGL157W 0.386156925 0.65070353 0.457460522 "AMS1 -- cell wall catabolism -- Alpha-mannosidase, hydrolyzes terminal non-reducing alpha-D-mannose residues from alpha-D-mannosides" YGR025W YGR025W 0.2 19 0.4 0.0669 0.467004247 0.678443795 YGR025W -- unknown -- unknown functionquestionable ORF YGR064W YGR064W 0.2 24 0.4 0.0669 0.258295088 0.144330734 YGR064W -- unknown -- unknown functionquestionable ORF YGR070W ROM1 0.2 26 0.4 0.0669 0.561532749 iYGR069W 0.47371783 0.385748375 0.299788824 ROM1 -- signaling -- GDP-GTP exchange factor for Rho1p YGR112W SHY1 0.2 16 0.4 0.0669 0.446543958 iYGR111W 0.482662266 0.900159617 0.469034318 SHY1 -- respiration -- Mitochondrial respiration YGR153W YGR153W 0.2 16 0.4 0.0669 0.065002614 iYGR152C 0.083265828 0.07617051 0.1424703 YGR153W -- unknown -- unknown function YHL009C YAP3 0.2 20 0.4 0.0669 0.677948435 iYHL009C YHLCsigma1 0.450333289 0.593596864 0.984612853 0.352812718 0.529655289 "YAP3 -- transcription -- Transcription factor of basic leucine zipper (bZIP) family, one of eight members of a novel fungal-specific family of bZIP proteins" YHR171W APG7 0.2 23 0.4 0.0669 0.568102206 iYHR170W 0.508270173 0.852145995 0.787090233 "APG7 -- autophagy -- Apg12p-activating enzyme, involved in autophagy, cytoplasm-to-vacuole protein targeting, and peroxisome degradation pathways" YIL084C SDS3 0.2 21 0.4 0.0669 0.237006443 iYIL084C 0.747584257 0.457459818 0.571155541 SDS3 -- silencing -- Suppressor of silencing defect YIL159W BNR1 0.2 22 0.4 0.0669 0.269193074 iYIL160C 0.072833161 0.358342081 0.10771003 "BNR1 -- cytoskeleton -- Bni1p-related protein, potential target of Rho4p" YIL166C YIL166C 0.2 20 0.4 0.0669 0.643819258 iYIL166C 0.232684261 0.87196577 0.34454191 YIL166C -- unknown -- similarity to members of Dal5p and other members of allantoate permease family of major facilitator superfamily (MFS) YIL172C YIL172C 0.2 14 0.4 0.0669 0.350847955 iYIL172C 0.180218146 0.67708669 0.411423198 "YIL172C -- unknown -- similarity to alpha-D-glucosidase (maltase), identical to Fsp2p and nearly identical to Ygr287p" YIR009W MSL1 0.2 16 0.4 0.0669 0.400990747 iYIR008C 0.637448366 0.726781169 0.369766879 "MSL1 -- mRNA splicing -- U2 snRNA-associated similarity to U2B"" protein, has one RNA recognition (RRM) domain" YIR028W DAL4 0.2 18 0.4 0.0669 0.111065269 iYIR027C 0.374065439 0.758459555 0.861268823 "DAL4 -- allantoin utilization -- Allantoin permease, member of uracil/allantoin permease family of membrane transporters" YJL013C MAD3 0.2 16 0.4 0.0669 0.244212262 iYJL013C 0.596167898 0.35562359 0.503588294 MAD3 -- cell cycle -- Spindle-assembly checkpoint cell cycle delay in response to impaired kinetochore function YJL058C YJL058C 0.2 22 0.4 0.0669 0.320141243 iYJL058C 0.522802072 0.542802236 0.289908849 YJL058C -- unknown -- unknown function YJL070C YJL070C 0.2 15 0.4 0.0669 0.234549736 iYJL070C 0.692438715 0.200373619 0.443622813 YJL070C -- unknown -- similarity to rat AMP deaminase 1 YJL149W YJL149W 0.2 25 0.4 0.0669 0.5136944 0.638028701 "YJL149W -- unknown -- unknown function, contains a cyclin F-box" YJL169W YJL169W 0.2 16 0.4 0.0669 0.744843494 iYJL170C 0.378666365 0.812520142 0.634096816 YJL169W -- unknown -- unknown functionquestionable ORF YJL185C YJL185C 0.2 21 0.4 0.0669 0.467180418 iYJL185C 0.369670928 0.804872146 0.504548408 YJL185C -- unknown -- unknown function YJR087W YJR087W 0.2 18 0.4 0.0669 0.727095292 0.879280224 YJR087W -- unknown -- unknown function YJR129C YJR129C 0.2 21 0.4 0.0669 0.753132962 iYJR129C 0.606015535 0.683317089 0.356792835 "YJR129C -- unknown -- unknown function, has similarity to Ynl024p" YJR138W IML1 0.2 24 0.4 0.0669 0.749486714 iYJR137C 0.649887848 0.53151397 0.734468855 "IML1 -- plasmid maintenance (outative) -- unknown function, has a role in stability of artificial minichromosomes" YJR146W YJR146W 0.2 22 0.4 0.0669 0.956713294 iYJR145C 0.990511147 0.931364725 0.710817133 YJR146W -- unknown -- unknown function YJR155W AAD10 0.2 19 0.4 0.0669 0.530910845 iYJR154W 0.226143583 0.827285444 0.465583508 "AAD10 -- unknown -- Putative aryl alcohol dehydrogenase, may participates in late steps of degradation of aromatic compounds that arise from the degradation of lignocellulose" YKL103C LAP4 0.2 24 0.4 0.0669 0.557838852 iYKL103C 0.630840503 0.886967156 0.62676454 "LAP4 -- protein degradation -- Aminopeptidase I (yscI, API) of vacuole" YKL199C YKT9 0.2 27 0.4 0.0669 0.76920538 0.387190449 YKT9 -- unknown -- unknown function YKL220C FRE2 0.2 20 0.4 0.0669 0.57012445 iYKL220C-0 iYKL220C-1 0.678752311 0.418113304 0.660670631 0.561524968 0.720834676 "FRE2 -- iron homeostasis -- Ferric and cupric reductase, paralog of Fre1p subject to regulation by iron" YKR101W SIR1 0.2 25 0.4 0.0669 0.726326227 iYKR100C 0.45415606 0.494152047 0.399774139 "SIR1 -- silencing -- establishment of silencing at HMR and HML, not required for establishment of telomere silencing" YKR104W YKR104W 0.2 21 0.4 0.0669 0.421611311 iYKR103W 0.375758397 0.490412504 0.243156472 YKR104W -- unknown -- Member of ATP-binding cassette (ABC) superfamily YLR070C YLR070C 0.2 17 0.4 0.0669 0.282591884 iYLR070C 0.519978587 0.764294997 0.387723196 YLR070C -- unknown -- Xylitol dehydrogenase YLR098C CHA4 0.2 21 0.4 0.0669 0.428794709 iYLR098C 0.330609956 0.504402205 0.200128908 "CHA4 -- ser/thr metabolism -- Zinc-finger transcriptional activation of CHA1, has a Zn[2]-Cys[6] fungal-type binuclear cluster domain" YLR288C MEC3 0.2 22 0.4 0.0669 0.988059734 iYLR288C 0.827774579 0.717028313 0.701298701 MEC3 -- DNA repair; DNA damage checkpoint -- Checkpoint arrest in G2 after DNA damage and for delaying in G1- and S-phase during DNA damage YLR306W UBC12 0.2 18 0.4 0.0669 0.330222958 iYLR305C 0.766007841 0.557004618 0.519249513 "UBC12 -- protein degradation, ubiquitin-mediated -- Rub1p-conjugating enzyme, with similarity to ubiquitin- and ubiquitin-like protein-conjugating enzymes" YLR320W YLR320W 0.2 21 0.4 0.0669 0.347299007 iYLR319C 0.329794185 0.316876491 0.229974994 YLR320W -- unknown -- unknown function YLR444C YLR444C 0.2 21 0.4 0.0669 0.291113128 iYLR444C 0.576839399 0.421825268 0.493527437 YLR444C -- unknown -- unknown function YMR153C-A 0.2 16 0.4 0.0669 0.480896876 iYMR153C-A 0.105929435 0.085038986 0.05214425 YMR154C RIM13 0.2 22 0.4 0.0669 0.635745508 iYMR154C 0.511134336 0.85770567 0.799521149 RIM13 -- sporulation -- Sporulation proteolytic processing of Rim1p YMR210W YMR210W 0.2 25 0.4 0.0669 0.354621692 iYMR209C 0.433563675 0.811898297 0.701676062 YMR210W -- unknown -- unknown function YMR232W FUS2 0.2 19 0.4 0.0669 0.341539897 iYMR231W 0.350027234 0.701061101 0.215678376 FUS2 -- mating; cell fusion -- cell fusion during matingfound in dots beneath the tip of mating projection (shmoo) YMR325C 0.2 21 0.4 0.0669 YNL009W IDP3 0.2 22 0.4 0.0669 0.636461224 iYNL010W 0.832994307 0.836663418 0.767053402 IDP3 -- TCA cycle -- NADP-dependent isocitrate dehydrogenase of peroxisomes YNL143C YNL143C 0.2 16 0.4 0.0669 0.869075067 iYNL143C 0.480464131 0.863872645 0.277809147 YNL143C -- unknown -- unknown function YNL277W MET2 0.2 20 0.4 0.0669 0.094152388 iYNL278W 0.22892905 0.264015725 0.573986723 "MET2 -- methionine biosynthesis -- Homoserine O-acetyltransferase, converts homoserine + acetyl-CoA to O-acetylhomoserine + CoA" YOL013C HRD1 0.2 26 0.4 0.0669 0.328457261 iYOL013C 0.54719642 0.472709552 0.273955539 HRD1 -- protein degradation -- endoplasmic reticulum-associated degradation of misfolded lumenal and integral membrane proteins YOL157C YOL157C 0.2 16 0.4 0.0669 0.243413547 iYOL157C 0.228508985 0.694811473 0.291666667 YOL157C -- unknown -- Probable alpha-glucosidase YOR049C YOR049C 0.2 25 0.4 0.0669 iYOR049C 0.308900857 0.352723171 YOR049C -- unknown -- unknown function YOR070C GYP1 0.2 23 0.4 0.0669 0.201381708 iYOR070C-0 iYOR070C-1 0.348549647 0.233990741 0.635941196 0.463503062 0.600193258 GYP1 -- signaling -- GTPase-activating protein for Ypt1p and Sec4p YOR114W YOR114W 0.2 20 0.4 0.0669 0.198315267 iYOR113W 0.369322647 0.360651691 0.315395376 YOR114W -- unknown -- unknown function YOR180C DCI1 0.2 21 0.4 0.0669 0.84374241 iYOR180C 0.620153638 0.772558814 0.678793256 DCI1 -- fatty acid metabolism -- Peroxisomal dienoyl-CoA isomerase YOR313C SPS4 0.2 21 0.4 0.0669 0.841099293 iYOR313C 0.648962339 0.18851527 0.189864326 "SPS4 -- sporulation -- expressed in mid-late (8-14 hr) sporulation, possible cell wall component" YOR349W CIN1 0.2 19 0.4 0.0669 0.362610671 iYOR348C 0.632199375 0.252319109 0.502782931 "CIN1 -- mitosis, chromosome segregation -- chromosome segregation, required for microtubule stability" YPL114W YPL114W 0.2 18 0.4 0.0669 0.230164944 iYPL115C 0.248894734 0.42945874 0.235540857 YPL114W -- unknown -- unknown function YPL116W HOS3 0.2 18 0.4 0.0669 0.175866151 iYPL117C 0.163108505 0.108674464 0.118571546 "HOS3 -- unknown -- Histone deacetylase, has similarity to Hda1p, Rpd3p, Hos2p, and Hos1p, insensitive to trichostatin A" YPL164C MLH3 0.2 23 0.4 0.0669 0.603868145 iYPL164C 0.641452519 0.744521431 0.524929291 MLH3 -- unknown -- Insertion and deletion mismatch repair protein YPL175W SPT14 0.2 23 0.4 0.0669 0.625625063 iYPL176C 0.741214169 0.794311956 0.732597486 "SPT14 -- protein processing -- N-acetylglucosaminyltransferase, required for GPI anchor synthesis" YPL192C YPL192C 0.2 23 0.4 0.0669 0.431355038 iYPL192C 0.478298679 0.671285852 0.527473413 YPL192C -- unknown -- unknown function YPL261C YPL261C 0.2 17 0.4 0.0669 0.438131408 0.60433976 YPL261C -- unknown -- unknown function YPL272C YPL272C 0.2 20 0.4 0.0669 0.20470674 iYPL272C-0 iYPL272C-1 0.144273674 0.26695951 0.242225716 0.324685788 0.328911795 YPL272C -- unknown -- unknown function YPR005C HAL1 0.2 23 0.4 0.0669 0.147581381 iYPR005C 0.101927475 0.167103424 0.111102159 HAL1 -- salt tolerance -- ion homeostasis YPR049C YPR049C 0.2 23 0.4 0.0669 0.401014123 iYPR049C 0.401912281 0.596261356 0.3 "YPR049C -- unknown -- unknown function, has a probable coiled-coil domain" YAR053W YAR053W 0.1 16 0.4 0.0669 0.76888804 iYAR050W 0.593463671 0.869912211 0.746725455 YAR053W -- unknown -- unknown function YDL152W YDL152W 0.1 13 0.4 0.0669 0.276608712 0.304382855 YDL152W -- unknown -- unknown function YDL183C YDL183C 0.1 16 0.4 0.0669 0.981102176 iYDL183C-0 iYDL183C-1 0.885366271 0.361871438 0.706145251 0.777015164 0.315139701 "YDL183C -- unknown -- unknown function, has potential mitochondrial import sequence" YDR022C CIS1 0.1 14 0.4 0.0669 0.166814534 iYDR022C itV(UAC)D 0.483787303 0.85656946 0.126401549 0.172948971 0.758579409 CIS1 -- microtubule assembly -- Protein potentially involved in spindle formationoverproduction suppresses growth defect of a cik1 null mutant YEL061C CIN8 0.1 14 0.4 0.0669 0.653106692 iYEL061C 0.467819074 0.468032585 0.226526966 "CIN8 -- mitosis, spindle maintenance -- Kinesin-related establishment and maintenance of mitotic spindle" YFL010W-A 0.1 15 0.4 0.0669 0.107622293 iYFL011W 0.690510779 0.323082122 0.847086991 YGR131W YGR131W 0.1 15 0.4 0.0669 0.409134392 iYGR130C 0.078472285 0.601192394 0.222186752 YGR131W -- unknown -- unknown function YGR287C YGR287C 0.1 14 0.4 0.0669 0.330771773 iYGR287C 0.154848632 0.700798085 0.422118254 "YGR287C -- unknown -- similarity to alpha-D-glucosidase (maltase), nearly identical to Fsp2p and Yil172p" YHR176W YHR176W 0.1 15 0.4 0.0669 0.813409438 iYHR175W 0.012303707 0.918063165 YHR176W -- unknown -- similarity to flavin-containing monooxygenases and to mammalian dimethylalanine monooxygenases YIL120W YIL120W 0.1 11 0.4 0.0669 0.448017003 iYIL121W 0.342674165 0.751624431 0.2620218 YIL120W -- unknown -- Member of multidrug-resistance 12-spanner family of major facilitator superfamily (MFS-MDR) YIR020C YIR020C 0.1 14 0.4 0.0669 0.782170983 iYIR020C YIR020W-B 0.329710794 0.476121094 0.629385965 0.203550095 0.603591381 YIR020C -- unknown -- unknown function YJL083W YJL083W 0.1 13 0.4 0.0669 0.31809716 iYJL084C 0.114800199 0.543103448 0.227268987 "YJL083W -- unknown -- unknown function, has similarity to Irs4p, contains an Eps homology (EH) domain" YJL160C YJL160C 0.1 14 0.4 0.0669 0.296423124 iYJL160C-0 iYJL160C-1 0.355272804 0.161684393 0.634266355 0.578354298 0.282494759 YJL160C -- unknown -- similarity to members of Pir1p/Hsp150p/Pir3p family YJR095W SFC1 0.1 12 0.4 0.0669 0.455947281 iYJR094W-A 0.631204914 0.882471566 0.782202713 "SFC1 -- transport -- Mitochondrial membrane succinate-fumarate transporter, member of mitochondrial carrier (MCF) family" YJR153W PGU1 0.1 16 0.4 0.0669 0.271975214 iYJR152W 0.1663454 0.667096358 0.435379554 "PGU1 -- unknown -- Endopolygalacturonase, pectin-hydrolyzing enzyme" YKR078W YKR078W 0.1 15 0.4 0.0669 0.320423511 iYKR077W 0.317999831 0.484876648 0.290231508 YKR078W -- unknown -- similarity to Uso1p YLR230W 0.1 15 0.4 0.0669 0.394350933 0.712213986 YMR094W CTF13 0.1 17 0.4 0.0669 0.209244845 iYMR093W 0.544546281 0.480187166 0.664757603 "CTF13 -- mitosis -- Component (subunit c) of Cbf3 kinetochore complex, contains an F-box domain" YMR320W YMR320W 0.1 12 0.4 0.0669 0.866444751 iYMR319C-0 iYMR319C-1 0.574810016 0.490153549 0.638343026 0.732033516 0.34094174 "YMR320W -- unknown -- unknown function, questionable ORF" YNL014W YEF3B 0.1 14 0.4 0.0669 0.372290043 iYNL015W 0.350427761 0.623714309 0.206331782 "YEF3B -- unknown -- Translation elongation factor EF-3B, member of non-transporter group of ATP-binding cassette (ABC) superfamily" YNL204C SPS18 0.1 16 0.4 0.0669 0.446820484 iYNL204C 0.83387815 0.438196953 0.703179595 SPS18 -- sporulation -- Sporulation-specific zinc finger activation of sporulationmember of Gcs1p/Glo3p/Sps18p family YNR071C YNR071C 0.1 13 0.4 0.0669 0.768267782 iYNR071C 0.33966574 0.979455366 0.356903432 YNR071C -- unknown -- similarity to UDPglucose 4-epimerase YOL152W FRE7 0.1 14 0.4 0.0669 0.568114995 iYOL153C-0 iYOL153C-1 0.401735383 0.792569299 0.289879792 "FRE7 -- unknown -- weak similarity to Fre1p and Fre2p, subject to regulation by copper" YOR237W HES1 0.1 15 0.4 0.0669 0.178954881 iYOR236W 0.358509389 0.141181165 0.328869888 "HES1 -- sterol metabolism -- implicated in ergosterol biosynthesis, member of KES1/HES1/OSH1/YKR003W family of oxysterol-binding (OSBP) proteins" YOR388C FDH1 0.1 14 0.4 0.0669 0.433759594 iYOR388C 0.658255661 0.112706996 0.341049383 FDH1 -- unknown -- similarity to formate dehydrogenases YPL018W CTF19 0.1 14 0.4 0.0669 0.776913544 iYPL019C 0.773113362 0.522389321 0.740009747 "CTF19 -- mitosis, chromosome segregation -- important for chromosome segregation" YPL077C YPL077C 0.1 15 0.4 0.0669 0.365068728 iYPL077C 0.690891551 0.598643256 0.528353634 YPL077C -- unknown -- similarity to Ybr197p YPR050C 0.1 14 0.4 0.0669 0.196120027 0.202545923 YDR042C YDR042C 0.1 15 0.3 0.0327 1 0.724229711 iYDR042C SNR47 0.676127926 0.755058864 0.377473562 0.027050182 0.194892259 YDR042C -- unknown -- unknown function YDL021W GPM2 0.1 16 0.3 0.0327 1 0.936374333 iYDL022W 0.944144079 0.591620112 0.775775529 "GPM2 -- glycolysis -- Phosphoglycerate mutase, with similarity to Gpm1p and Gpm3p" YCR036W RBK1 0.8 90 0.3 0.0327 0.316266264 iYCR035C 0.292014083 0.610761705 0.319606888 "RBK1 -- ribose metabolism -- Ribokinase, member of a family of sugar kinases that includes Pfk2p" YHR099W TRA1 0.8 84 0.3 0.0327 0.689520906 iYHR098C 0.274049424 0.410409281 0.359749916 "TRA1 -- unknown -- Component of Ada-Spt transcriptional regulatory complex, SAGA (Spt-Ada-Gcn5-Acetyltransferase) complex, SLIK (SAGA-LIKe) complex, and NuA4 (NUcleosome Acetylase of histone H4) complex" YCR026C YCR026C 0.7 77 0.3 0.0327 0.759562352 iYCR026C 0.462355456 0.634317638 0.683946351 YCR026C -- unknown -- similarity to human plasma membrane glycoprotein PCI YMR197C VTI1 0.7 74 0.3 0.0327 0.188098959 iYMR197C 0.156168865 0.551482436 0.628700492 "VTI1 -- secretion -- Synaptobrevin (v-SNARE) homolog, has an essential role at the cis-Golgi stage and a non-essential role at the Golgi to prevacuole stage" YOR223W YOR223W 0.6 55 0.3 0.0327 0.023988365 iYOR222W 0.629854661 0.046122756 0.347664758 YOR223W -- unknown -- unknown function YBR150C TBS1 0.4 57 0.3 0.0327 0.478866048 iYBR150C 0.594337097 0.792722648 0.574282952 "TBS1 -- drug resistance (putative) -- similarity to transcription factors, has Zn[2]-Cys[6] fungal-type binuclear cluster domain in the N-terminal region" YBR157C ICS2 0.4 45 0.3 0.0327 0.354881496 iYBR157C-0 iYBR157C-1 0.174167472 0.59197754 0.683451499 0.313366002 0.683438155 ICS2 -- Cu2+ ion homeostasis (putative) -- normal resistance to copper YBR280C YBR280C 0.4 59 0.3 0.0327 0.462020589 iYBR280C 0.721146824 0.836172139 0.77926483 YBR280C -- unknown -- similarity to Srm1p/Prp20p YCR014C POL4 0.4 55 0.3 0.0327 0.517566943 iYCR014C 0.701959992 0.48754988 0.42122905 "POL4 -- DNA repair -- DNA polymerase involved in DNA repair, related to human DNA polymerase beta" YCR029C 0.4 51 0.3 0.0327 YDL209C YDL209C 0.4 48 0.3 0.0327 iYDL209C 0.390009145 0.312091635 YDL209C -- unknown -- Putative spliceosomal similarity to S. pombe cwf2p YDR358W GGA1 0.4 50 0.3 0.0327 0.28514318 iYDR357C 0.500165262 0.816407195 0.37998848 GGA1 -- unknown -- trafficking of proteins between the trans-Golgi network and the vacuole YMR139W RIM11 0.4 51 0.3 0.0327 0.423688056 iYMR138W 0.176287062 0.542697526 0.226264419 RIM11 -- meiosis -- Serine/threonine protein kinase required for induction of IME2 by Ime1p YMR181C YMR181C 0.4 56 0.3 0.0327 0.116427037 iYMR181C 0.022555973 0.051804705 0.010152697 YMR181C -- unknown -- unknown function YNL063W YNL063W 0.4 50 0.3 0.0327 0.790876761 iYNL064C 0.283131546 0.927966443 0.530398323 "YNL063W -- unknown -- similarity to E. coli hemK, involved in protophorphyrinogen oxidase activity, has similarity to S-adenosyl-methionine-dependent methyltransferases" YNL140C YNL140C 0.4 62 0.3 0.0327 0.18085703 0.362184399 "YNL140C -- unknown -- unknown function, questionable ORF" YPR040W YPR040W 0.4 59 0.3 0.0327 0.120588472 0.057748538 YPR040W -- unknown -- unknown function YBL077W YBL077W 0.3 33 0.3 0.0327 0.759996762 iYBL078C 0.542594001 0.948455271 0.411864176 YBL077W -- unknown -- unknown function YBR168W YBR168W 0.3 45 0.3 0.0327 0.40084814 iYBR167C 0.377947818 0.756823623 0.486273554 YBR168W -- unknown -- Essential unknown function YCL012W YCL012W 0.3 32 0.3 0.0327 0.438815084 iYCL014W 0.350212349 0.284706879 0.368989604 YCL012W -- unknown -- unknown function YCR018C SRD1 0.3 32 0.3 0.0327 0.761650075 iYCR018C iYCRWdelta8 0.180177769 0.519080046 0.462962963 0.214459227 0.426495438 "SRD1 -- rRNA processing -- Nucleolar pre-rRNA processing, but does not bind to small nucleolar RNA (snoRNA)" YCR020C PET18 0.3 56 0.3 0.0327 0.705113754 iYCR020C 0.427964529 0.68431167 0.768208186 PET18 -- mitochondrial DNA maintenance -- maintenance of mitochondrial DNA YCR094W CDC50 0.3 41 0.3 0.0327 0.865342873 iYCR093W 0.413812853 0.98140026 0.473743017 CDC50 -- cell cycle -- leads to a cell-division-cycle (CDC) phenotype when mutated YDL106C GRF10 0.3 46 0.3 0.0327 0.204967601 iYDL106C 0.136247551 0.066314181 0.217472119 GRF10 -- phosphate signaling -- Homeodomain expression of phosphate pathway and other genes YDL223C YDL223C 0.3 38 0.3 0.0327 0.171146267 iYDL223C 0.428727584 0.219423618 0.20055905 "YDL223C -- unknown -- repeated region characteristic of neuraxin and Map1b proteins, also has ATP/GTP-binding site motif A" YDR371W YDR371W 0.3 40 0.3 0.0327 0.240130487 iYDR370C 0.561744994 0.803511572 0.606509829 YDR371W -- unknown -- similarity to chitinases YDR480W DIG2 0.3 45 0.3 0.0327 0.128528635 iYDR479C 0.098575959 0.221086653 0.226656026 DIG2 -- invasive growth -- MAP kinase-associated proteininvolved in negative regulation of invasive growth and mating response YER037W YER037W 0.3 40 0.3 0.0327 0.813877517 iYER036C 0.553555565 0.977222427 0.314924182 YER037W -- unknown -- unknown function YER077C YER077C 0.3 44 0.3 0.0327 0.319574572 iYER077C 0.689290189 0.87665597 0.404756027 YER077C -- unknown -- similarity to class I tRNA synthetases YGR170W PSD2 0.3 37 0.3 0.0327 0.193687408 iYGR169C 0.162408503 0.677174781 0.098736018 "PSD2 -- phospholipid metabolism -- Phosphatidylserine decarboxylaseGolgi and vacuolar isozyme, converts phosphatidyl-L-serine to phosphatidylethanolamine" YHR075C PPE1 0.3 42 0.3 0.0327 0.520664934 iYHR075C 0.31943465 0.753488747 0.271269739 PPE1 -- protein synthesis -- Mitochondrial ribosomal small subunit YHR090C YNG2 0.3 43 0.3 0.0327 0.156913008 iYHR090C 0.340578368 0.604985077 0.478055959 YNG2 -- unknown -- Component of NuA4 histone acetyltransferase complex with effect on BEM and RAD phenotypes YHR168W YHR168W 0.3 38 0.3 0.0327 0.190954037 iYHR167W 0.237624131 0.855536951 0.274447693 "YHR168W -- unknown -- Putative GTP-binding protein, has a GTP1/OBG domain" YJL048C YJL048C 0.3 44 0.3 0.0327 0.184848751 iYJL048C SNR60 0.586471041 0.765204641 0.375818037 0.443575058 0.415576754 YJL048C -- unknown -- unknown function YJR021C REC107 0.3 34 0.3 0.0327 0.319129233 iYJR021C 0.306821307 0.434954332 0.035913807 "REC107 -- meiosis, recombination -- Meiotic recombination protein, component of a complex that processes double-stranded DNA breaks" YJR035W RAD26 0.3 33 0.3 0.0327 0.118315387 iYJR034W 0.515317055 0.216806316 0.331881027 "RAD26 -- DNA repair -- Putative helicase involved in transcription-coupled repair, homolog of Cockayne syndrome B gene ERCC-6" YKR058W GLG1 0.3 42 0.3 0.0327 0.318783044 iYKR057W 0.545754403 0.608040288 0.405310971 GLG1 -- glycogen metabolism -- Self-glucosylating initiator of glycogen synthesis YLL056C YLL056C 0.3 36 0.3 0.0327 0.336200659 iYLL056C-0 iYLL056C-1 0.272481281 0.467902053 0.592804711 0.468079922 0.671291441 "YLL056C -- unknown -- weak similarity to Y. pseudotuberculosis CDP-3, 6-dideoxy-D-glycero-L-glycero-4-hexulose-5-epimerase" YLR006C SSK1 0.3 34 0.3 0.0327 0.460651153 iYLR006C 0.247932351 0.702713488 0.283000798 SSK1 -- signaling -- Two-component signal transducer that receives phosphate from the Sln1p-Ypd1p phosphorelay as part of high-osmolarity signal transduction MAP kinase pathway YLR108C YLR108C 0.3 38 0.3 0.0327 0.631436938 iYLR108C 0.447390395 0.813438907 0.492924528 YLR108C -- unknown -- unknown function YLR207W HRD3 0.3 45 0.3 0.0327 0.507942577 iYLR206W 0.390229936 0.830846172 0.1973058 HRD3 -- protein degradation -- efficient degradation of Hmg CoA reductase isozyme Hmg2p YLR238W YLR238W 0.3 43 0.3 0.0327 0.055155297 iYLR237W 0.155903627 0.103089457 0.433653303 YLR238W -- unknown -- unknown function YML034W SRC1 0.3 39 0.3 0.0327 0.289251548 0.294697215 "SRC1 -- unknown -- unknown function, expression is cell cycle-regulated" YMR060C TOM37 0.3 36 0.3 0.0327 0.407951162 iYMR060C 0.406373599 0.614727683 0.300439338 "TOM37 -- mitochondrial protein targeting -- Component of mitochondrial outer membrane receptor complex, needed only at high temperature, has tetratricopeptide (TPR) repeats" YMR104C YPK2 0.3 35 0.3 0.0327 0.424113115 iYMR104C 0.520073128 0.793763103 0.355220933 YPK2 -- unknown -- Serine/threonine protein kinase with similarity to Ypk1p YOL096C COQ3 0.3 46 0.3 0.0327 0.090212208 iYOL096C 0.383066904 0.423845964 0.115533355 "COQ3 -- ubiquinone biosynthesis -- 3-Demethylubiquinone-9 3-methyltransferase (3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase or DHHB methyltransferase), fourth and rate limiting step in coenzyme Q (ubiquinone) biosynthesis pathway" YOL100W PKH2 0.3 40 0.3 0.0327 0.211253782 iYOL101C 0.277357888 0.228926353 0.578285069 PKH2 -- unknown -- Serine/threonine protein kinase with similarity to mammalian 3-phosphoinositide-dependent protein kinase YOR058C ASE1 0.3 36 0.3 0.0327 0.646851438 iYOR058C-0 iYOR058C-1 0.473868597 0.289386341 0.626409926 0.64444993 0.632801277 "ASE1 -- mitosis -- Microtubule-associated protein localized to the spindle midzone, required for anaphase spindle elongation" YOR120W GCY1 0.3 46 0.3 0.0327 0.258016668 iYOR119C 0.645225185 0.546019198 0.779396034 GCY1 -- unknown -- Galactose-induced strong similarity to crystallin vertebrate eye lens YOR162C YRR1 0.3 41 0.3 0.0327 0.922831353 iYOR162C 0.239211156 0.598936513 0.301240735 "YRR1 -- transport -- Transcription factor involved in drug-induced transcriptional activation of multidrug transporter gene SNQ2, has a Zn[2]-Cys[6] fungal-type binuclear cluster domain" YAL028W YAL028W 0.2 29 0.3 0.0327 0.500354659 iYAL029C 0.522747814 0.5256917 0.543586851 YAL028W -- unknown -- unknown function YAR069C YAR069C 0.2 21 0.3 0.0327 0.637300497 iYAR069C 0.557823824 0.552633702 0.63055578 "YAR069C -- unknown -- unknown function, has 3 potential membrane spanning regions" YBR030W YBR030W 0.2 34 0.3 0.0327 0.549551668 iYBR029C 0.483721685 0.714852991 0.466000645 YBR030W -- unknown -- weak similarity to Sin3p YBR131W CCZ1 0.2 29 0.3 0.0327 0.274103906 iYBR130C 0.308375426 0.734855207 0.419057691 "CCZ1 -- calcium, caffeine, and zinc sensitivity -- growth in media containing calcium, caffeine or zinc, also required for sporulation" YBR136W MEC1 0.2 40 0.3 0.0327 0.551501556 iYBR135W 0.0509624 0.458524307 0.02521968 "MEC1 -- DNA repair and recombination -- Checkpoint mitotic growth, DNA repair and mitotic recombination, possible phosphatidylinositol kinase" YBR289W SNF5 0.2 25 0.3 0.0327 0.129444599 iYBR288C 0.423925634 0.11862334 0.35497408 "SNF5 -- transcription -- Component of SWI-SNF global transcription activator complex, acts to assist gene-specific activators through chromatin remodeling" YCL014W BUD3 0.2 27 0.3 0.0327 0.361031655 iYCL016C 0.276130391 0.669066016 0.710935571 "BUD3 -- cell polarity -- localized at the neck filament ring required for axial budding, may provide a memory of previous bud site" YCR106W YCR106W 0.2 20 0.3 0.0327 0.717232976 iYCR105W 0.891558831 0.309268371 0.941500399 "YCR106W -- unknown -- similarity to transcription factors, has Zn[2]-Cys[6] fungal-type binuclear cluster domain in the N-terminal region" YDL025C YDL025C 0.2 29 0.3 0.0327 0.322539558 iYDL025C 0.440045201 0.298743152 0.646916855 YDL025C -- unknown -- Serine/threonine protein kinase with similarity to members of NPR1 subfamily YDL057W YDL057W 0.2 24 0.3 0.0327 0.475226874 iYDL058W 0.394904385 0.87037037 0.669912211 YDL057W -- unknown -- unknown function YDL176W YDL176W 0.2 25 0.3 0.0327 0.372927574 iYDL177C 0.433686453 0.552703036 0.417027496 YDL176W -- unknown -- unknown function YDL248W COS7 0.2 27 0.3 0.0327 0.816533997 TEL3R 0.822747114 0.329795112 0.237345247 COS7 -- unknown -- Member of COS family of subtelomerically-encoded proteins YDR069C DOA4 0.2 27 0.3 0.0327 0.292415245 iYDR069C 0.596126902 0.523283919 0.832339671 "DOA4 -- protein degradation, ubiquitin-mediated -- Ubiquitin-specific protease (ubiquitin C-terminal hydrolase), involved in recycling ubiquitin from protein substrates targeted to the proteasome and the vacuole" YDR126W YDR126W 0.2 20 0.3 0.0327 0.389867663 iYDR125C 0.608321271 0.898148148 0.871420505 YDR126W -- unknown -- unknown function YDR330W YDR330W 0.2 31 0.3 0.0327 0.435432834 iYDR329C 0.160377593 0.900079808 0.189500535 YDR330W -- unknown -- Protein possibly involved in proteasome functionC-terminus has similarity to Undulin extracellular matrix glycoprotein YDR356W NUF1 0.2 26 0.3 0.0327 0.307718033 0.429620069 "NUF1 -- cytoskeleton -- Spindle pole body component with coiled-coil structure, determines the spacing between the ends of microtubules and the central plaque" YDR484W SAC2 0.2 25 0.3 0.0327 0.288912502 iYDR483W 0.60731787 0.694149593 0.395020947 "SAC2 -- cytoskeleton -- Subunit of Vps52p-Vps53p-Vps54p complex, involved in protein sorting in the late Golgi" YDR515W SLF1 0.2 22 0.3 0.0327 0.219016865 iYDR514C 0.540930352 0.451781886 0.684676776 "SLF1 -- Cu2+ ion homeostasis -- Ribosome-associated protein possibly involved in regulation of copper-dependent mineralization of copper complexes on the cell surface, member of a subfamily of La motif proteins" YER129W PAK1 0.2 25 0.3 0.0327 0.374837964 iYER128W 0.537215981 0.847245691 0.483725427 PAK1 -- DNA replication -- kinase capable of suppressing DNA polymerase alpha mutations YFL058W THI5 0.2 33 0.3 0.0327 0.479243551 iYFL059W 0.07043426 0.881010396 0.042787789 "THI5 -- pyrimidine biosynthesis -- Biosynthetic enzyme involved in pyrimidine biosynthesis pathway, involved in conversion of hydroxymethyl-pyrimidine precursor to thymidineThi5p, Thi11p, Thi12p and Thi13p are nearly identical" YFR017C YFR017C 0.2 28 0.3 0.0327 0.455495686 iYFR017C 0.945442772 0.175663871 0.354934099 YFR017C -- unknown -- unknown function YGL045W YGL045W 0.2 28 0.3 0.0327 0.335281936 iYGL046W 0.327190063 0.607138666 0.25506928 YGL045W -- unknown -- unknown function YGR110W YGR110W 0.2 22 0.3 0.0327 0.514017908 iYGR109C iYGRWsigma5 0.598915331 0.235308305 0.866846908 0.214912281 0.448180637 "YGR110W -- unknown -- unknown function, induced during aerobic growth" YGR248W SOL4 0.2 30 0.3 0.0327 0.648619383 iYGR247W 0.312411966 0.89013471 0.18188348 SOL4 -- unknown -- Possible 6-phosphogluconolactonase YGR289C MAL11 0.2 25 0.3 0.0327 0.333135003 0.666229909 "MAL11 -- transport -- General alpha-glucoside permease, maltose permease, member of hexose transporter family of major facilitator superfamily (MFS)" YIL045W PIG2 0.2 27 0.3 0.0327 0.290064761 iYIL046W 0.170316784 0.581672985 0.255317435 "PIG2 -- glucose repression -- interacts with Gsy2p, possible regulatory subunit for the PP1-family protein phosphatase Glc7p" YIL146C ECM37 0.2 31 0.3 0.0327 0.453953761 iYIL146C 0.395017729 0.77842755 0.554785691 ECM37 -- cell wall biogenesis -- Protein possibly involved in cell wall structure or biosynthesis YIR031C DAL7 0.2 28 0.3 0.0327 0.536929801 iYIR031C 0.7366922 0.901402501 0.812938614 "DAL7 -- allantoin utilization -- Malate synthase 2, involved in degradation of allantoinvery similar to Mls1p" YJL163C YJL163C 0.2 37 0.3 0.0327 0.513447145 iYJL163C 0.166796384 0.792458911 0.380127694 YJL163C -- unknown -- unknown function YJL222W VTH2 0.2 33 0.3 0.0327 0.437274075 iYJL223C-0 iYJL223C-1 0.895785691 0.376250511 0.495929769 0.413791666 0.190164221 "VTH2 -- vacuolar protein targeting -- similarity to Pep1p, Vth1p, Ycr099p, Ycr100p, and Ycr101pcontains PEST sequences in the C-terminal regions as does Pep1p" YKL042W SPC42 0.2 32 0.3 0.0327 0.477480763 iYKL043W 0.372031771 0.484714044 0.382202713 SPC42 -- cytoskeleton -- Component of spindle pole body YKL133C YKL133C 0.2 24 0.3 0.0327 0.836235661 iYKL133C 0.66939663 0.879890296 0.868730064 YKL133C -- unknown -- unknown function YKL161C YKL161C 0.2 36 0.3 0.0327 0.639429965 iYKL161C-0 iYKL161C-1 0.228181122 0.338853606 0.859074011 0.44507529 0.15266608 YKL161C -- unknown -- Serine/threonine protein kinase with similarity to MAP kinases YKR023W YKR023W 0.2 36 0.3 0.0327 0.067029433 iYKR022C 0.220756266 0.18547486 0.389146049 YKR023W -- unknown -- unknown function YKR053C YSR3 0.2 32 0.3 0.0327 0.482791242 iYKR053C 0.553049395 0.908233967 0.684440056 "YSR3 -- sphingolipid metabolism -- Sphingoid base-phosphate phosphatase, putative regulator of sphingolipid metabolism and stress response" YKR098C UBP11 0.2 30 0.3 0.0327 0.445539961 iYKR098C 0.361025784 0.752533194 0.268611022 "UBP11 -- protein degradation, ubiquitin-mediated -- Ubiquitin-specific protease, ubiquitin C-terminal hydrolase" YLR121C YPS3 0.2 26 0.3 0.0327 0.367867634 iYLR121C 0.238297254 0.426735834 0.374122772 YPS3 -- protein processing -- GPI-anchored aspartyl protease YLR173W YLR173W 0.2 23 0.3 0.0327 0.562424291 iYLR172C 0.709008188 0.873776022 0.656743815 YLR173W -- unknown -- unknown function YLR457C NBP1 0.2 23 0.3 0.0327 0.13844166 0.132899628 NBP1 -- unknown -- Essential G2/M transition YMR053C STB2 0.2 37 0.3 0.0327 0.116658732 iYMR053C 0.263557887 0.342713733 0.259023526 STB2 -- unknown -- Sin3p-binding protein YMR085W 0.2 26 0.3 0.0327 0.409227704 iYMR084W 0.669337866 0.520430966 0.24533286 YMR155W YMR155W 0.2 23 0.3 0.0327 0.409078853 iYMR154C 0.511134336 0.561424988 0.799521149 YMR155W -- unknown -- unknown function YMR204C YMR204C 0.2 23 0.3 0.0327 0.29557098 iYMR204C 0.646095325 0.522340163 0.803034995 YMR204C -- unknown -- unknown function YMR316C-B 0.2 26 0.3 0.0327 0.07192868 0.049004193 YNL013C YNL013C 0.2 19 0.3 0.0327 0.096560963 iYNL013C 0.575759434 0.045684836 0.547354563 "YNL013C -- unknown -- unknown function, questionable ORF" YNL250W RAD50 0.2 21 0.3 0.0327 0.437824903 iYNL251C 0.614831754 0.746506239 0.627355426 RAD50 -- DNA repair -- Coiled-coil recombinational DNA repairneeded for resection at double-stranded breaks and required for DNA repair during vegetative growth YNL266W YNL266W 0.2 24 0.3 0.0327 0.18150469 iYNL267W 0.305974727 0.444213887 0.125071999 YNL266W -- unknown -- weak similarity to NADH dehydrogenases YOL117W YOL117W 0.2 23 0.3 0.0327 0.607676453 iYOL118C 0.671356218 0.837002096 0.728873529 YOL117W -- unknown -- unknown function YOR072W YOR072W 0.2 25 0.3 0.0327 0.43060034 iYOR071C 0.720590196 0.737184234 0.729322298 YOR072W -- unknown -- unknown function YOR146W YOR146W 0.2 21 0.3 0.0327 0.214992119 0.186254739 YOR146W -- unknown -- unknown function YOR195W SLK19 0.2 24 0.3 0.0327 0.253494144 iYOR194C 0.082918644 0.124837557 0.030527442 SLK19 -- mitosis -- involved with Kar3p in control of spindle dynamics YOR366W YOR366W 0.2 30 0.3 0.0327 0.952521822 0.534194282 YOR366W -- unknown -- unknown function YOR380W YOR380W 0.2 26 0.3 0.0327 0.350371669 iYOR379C 0.195319815 0.407471406 0.125802636 "YOR380W -- unknown -- similarity to transcription factors, has Zn[2]-Cys[6] fungal-type binuclear cluster domain in the N-terminal region" YPL153C RAD53 0.2 31 0.3 0.0327 0.522713262 iYPL153C 0.564158468 0.369152047 0.511807784 "RAD53 -- cell cycle, checkpoint -- Serine/threonine/tyrosine protein kinase with a checkpoint function in S and G2" YPL249C YPL249C 0.2 32 0.3 0.0327 0.912518965 iYPL249C 0.3629713 0.310662386 0.105263158 YPL249C -- unknown -- unknown function YPR045C YPR045C 0.2 27 0.3 0.0327 0.493181987 iYPR045C 0.503092843 0.536630929 0.254264993 "YPR045C -- unknown -- unknown function, has similarity to C. elegans F01F1.1 protein" YPR111W DBF20 0.2 21 0.3 0.0327 0.912019895 iYPR110C 0.953609909 0.322327044 0.316850851 DBF20 -- cell cycle -- Cell cycle protein kinase involved in termination of M-phaserelated to Dbf2p YPR152C YPR152C 0.2 28 0.3 0.0327 0.193557577 iYPR152C 0.266634288 0.22677063 0.260311268 YPR152C -- unknown -- similarity to Ykl012p YAL032C PRP45 0.1 18 0.3 0.0327 0.873897096 iYAL032C 0.797378363 0.707025893 0.894005848 "PRP45 -- mRNA splicing -- pre-mRNA splicing, component of spliceosome" YAL048C YAL048C 0.1 18 0.3 0.0327 0.48187107 iYAL048C 0.458744362 0.544968321 0.333629104 "YAL048C -- secretion (putative) -- the secretory pathway, has weak similarity to GTP-binding proteins of RAS superfamily" YAL058C-A YAL058C-A 0.1 14 0.3 0.0327 0.471462207 iYAL058C-A 0.511098201 0.591788036 0.639863548 YAL058C-A -- unknown -- unknown function YAR031W YAR031W 0.1 12 0.3 0.0327 0.424971215 0.617040286 "YAR031W -- unknown -- similarity to subtelomerically-encoded proteins such as Cos5p, Ybr302p, Cos3p, Cos1p, Cos4p, Cos8p, Cos6p, Cos9p, and Ycr007p" YBL031W SHE1 0.1 17 0.3 0.0327 0.396645926 iYBL032W 0.508197203 0.491634178 0.391487979 SHE1 -- unknown -- causes lethality when overexpressed YBR018C GAL7 0.1 18 0.3 0.0327 0.189488062 iYBR018C 0.518538513 0.619158879 0.770302933 GAL7 -- galactose metabolism -- UDP-glucose--hexose-1-phosphate uridylyltransferase YBR065C ECM2 0.1 18 0.3 0.0327 0.520350507 iYBR065C 0.588819088 0.866480447 0.583477331 "ECM2 -- cell wall biogenesis and mRNA splicing (putative) -- Putative pre-mRNA splicing factor, also involved in cell wall structure or biosynthesis" YBR128C APG14 0.1 13 0.3 0.0327 0.446951952 iYBR128C 0.331421347 0.763857557 0.172634952 APG14 -- autophagy -- autophagy YBR179C FZO1 0.1 19 0.3 0.0327 0.618407411 iYBR179C 0.929891866 0.635964912 0.383160415 "FZO1 -- mitochondrial biogenesis -- Transmembrane GTPase required for mitochondrial fusion and maintenance of mitochondrial DNA, has similarity to Drosophila melanogaster fzo" YBR190W YBR190W 0.1 15 0.3 0.0327 0.982354651 iYBR189W 0.983745083 0.814205906 0.6570013 YBR190W -- unknown -- weak similarity to glycosyl hydrolases YCR013C YCR013C 0.1 19 0.3 0.0327 0.915454104 iYCR013C 0.835241399 0.576349117 0.270188718 "YCR013C -- unknown -- unknown function, questionable ORF" YDL079C MRK1 0.1 18 0.3 0.0327 0.572576723 iYDL079C 0.087427613 0.465318389 0.224668064 MRK1 -- unknown -- Serine/threonine protein kinase with strong similarity to Rim11p YDL146W YDL146W 0.1 20 0.3 0.0327 0.78642846 iYDL147W 0.675975413 0.897391591 0.780214425 YDL146W -- unknown -- unknown function YDL216C YDL216C 0.1 17 0.3 0.0327 iYDL216C 0.792447549 0.436929153 YDL216C -- unknown -- unknown function YDL228C YDL228C 0.1 17 0.3 0.0327 0.261110719 iYDL228C 0.785266068 0.20094217 0.939178834 YDL228C -- unknown -- similarity to Achlya klebsiana glutamate dehydrogenase YDR242W AMD2 0.1 13 0.3 0.0327 0.137203007 iYDRWdelta12 itY(GUA)D 0.533649134 0.601039214 0.401030748 0.463288109 0.41991621 AMD2 -- unknown -- similarity to amidases YDR295C PLO2 0.1 17 0.3 0.0327 0.65423496 iYDR295C 0.269601437 0.729612003 0.226022425 PLO2 -- unknown -- unknown function YDR317W YDR317W 0.1 15 0.3 0.0327 0.460354547 iYDRWdelta24 0.243302547 0.723529891 0.500478851 YDR317W -- unknown -- unknown function YEL005C VAB2 0.1 18 0.3 0.0327 0.693544267 iYEL005C 0.673686345 0.908519233 0.595191683 VAB2 -- vacuolar protein targeting (putative) -- Vac8p-binding protein YEL030W ECM10 0.1 11 0.3 0.0327 0.512950507 iYEL031W 0.624777279 0.5174703 0.817673316 ECM10 -- cell wall biogenesis -- Protein possibly involved in cell wall structure or biosynthesis YER047C SAP1 0.1 16 0.3 0.0327 0.510073577 iYER047C 0.844869665 0.452753392 0.392594983 SAP1 -- mating type switching -- similarity to Yta6p and members of AAA family YER109C FLO8 0.1 16 0.3 0.0327 0.173683446 iYER109C 0.40168262 0.273148148 0.259104093 "FLO8 -- flocculation (and PHD) -- Putative transcriptional activator of FLO1, required for diploid filamentous growth" YER121W YER121W 0.1 17 0.3 0.0327 0.560904027 iYER120W 0.411634028 0.840724496 0.235355148 YER121W -- unknown -- unknown function YER179W DMC1 0.1 15 0.3 0.0327 0.467961934 iYER178W 0.430608939 0.809018349 0.510220126 "DMC1 -- meiosis, chromsome pairing -- Meiosis-specific recombination protein structurally related to S. cerevisiae Rad51p, Rad55p, Rad57p, and to E. coli RecA" YFL056C AAD6 0.1 20 0.3 0.0327 0.723576529 iYFL056C-0 iYFL056C-1 0.158689971 0.351080058 0.633701702 0.185028726 0.541179318 "AAD6 -- unknown -- Probable aryl alcohol dehydrogenase, may participate in late steps of degradation of aromatic compounds that arise from the degradation of lignocellulose" YFR035C YFR035C 0.1 13 0.3 0.0327 0.473871808 iYFR035C itK(CUU)F 0.797412873 0.23155265 0.711252993 0.392120894 0.217172782 YFR035C -- unknown -- unknown function YGR045C YGR045C 0.1 20 0.3 0.0327 0.469969241 iYGR045C 0.332604215 0.593780213 YGR045C -- unknown -- normal growth on nonfermentable carbon sources and for normal pseudohyphal growth YGR088W CTT1 0.1 24 0.3 0.0327 0.256691062 iYGR087C-0 iYGR087C-1 0.603275538 0.020492481 0.566397912 0.643780573 0.234509998 CTT1 -- oxidative stress response -- Catalase T (cytosolic) YGR126W YGR126W 0.1 15 0.3 0.0327 0.26013325 iYGR125W 0.325319003 0.664884278 0.197951117 YGR126W -- unknown -- unknown function YGR205W YGR205W 0.1 16 0.3 0.0327 0.429146172 iYGR204W 0.456030415 0.588796891 0.349357891 YGR205W -- unknown -- similarity to E. coli putrescine transport protein potI PIR YHL016C DUR3 0.1 23 0.3 0.0327 0.786099314 iYHL016C 0.966818835 0.931773879 0.291179337 "DUR3 -- transport -- Urea permease, member of solute" YHR035W YHR035W 0.1 14 0.3 0.0327 0.728340833 iYHR034C 0.452608731 0.475339186 0.396547552 "YHR035W -- unknown -- weak similarity to Sec23p, expressed under nitrogen-starvation conditions" YHR048W YHR048W 0.1 17 0.3 0.0327 0.684154096 iYHR047C-0 iYHR047C-1 0.568281211 0.249797636 0.809470033 0.629055652 0.14041906 YHR048W -- unknown -- Member of multidrug-resistance 12-spanner family of major facilitator superfamily (MFS-MDR) YHR139C SPS100 0.1 20 0.3 0.0327 0.332849909 iYHR139C 0.432536059 0.799226528 0.761128939 "SPS100 -- sporulation -- Sporulation specific spore wall formation, first appears at 12h of sporulation" YHR184W SSP1 0.1 17 0.3 0.0327 0.681113021 iYHR183W 0.344504969 0.860623782 0.160409281 "SSP1 -- meiosis,nuclear division and spore formation -- Meiosis-specific protein, required for proper completion of meiotic division and spore formation" YIL168W SDL1 0.1 17 0.3 0.0327 0.118739449 iYIL169C-0 iYIL169C-1 0.819254512 0.767069585 0.28045809 0.759668063 0.597491958 "SDL1 -- gluconeogenesis -- Serine dehydratase, converts serine to pyruvate and ammonia for gluconeogenesis" YIR042C YIR042C 0.1 15 0.3 0.0327 0.813320626 iYIR042C 0.822322901 0.635278282 0.334502261 YIR042C -- unknown -- unknown function YJL045W YJL045W 0.1 13 0.3 0.0327 0.415765913 iYJL046W itY(GUA)J1 0.769343184 0.742497034 0.646988674 0.70524831 0.403910615 "YJL045W -- unknown -- similarity to succinate dehydrogenase flavoprotein, has an FAD-binding domain, has strong similarity to OSM1" YJL106W IME2 0.1 15 0.3 0.0327 0.734069058 iYJL107C 0.55094345 0.966242346 0.747050921 "IME2 -- signaling, meiosis pathway -- Serine/threonine protein kinase and positive regulator of early, middle, and late meiotic genes" YJR053W BFA1 0.1 17 0.3 0.0327 0.285092602 iYJR052W 0.305892757 0.634420412 0.113358041 BFA1 -- unknown -- efficient mating YJR135C MCM22 0.1 14 0.3 0.0327 0.978787065 0.960000301 "MCM22 -- mitosis, chromosome segregation -- maintenance of chromosomes and minichrosomes" YJR160C YJR160C 0.1 18 0.3 0.0327 0.398187362 iYJR160C-0 iYJR160C-1 0.489585981 0.91550458 0.457197764 0.631927079 0.443469786 "YJR160C -- unknown -- strong similarity to maltose permeases (maltose/H+ symporters) Mal31p and Mal61p, member of hexose transporter family of major facilitator superfamily (MFS)" YKL026C GPX1 0.1 17 0.3 0.0327 0.664401636 iYKL026C 0.395824738 0.923862729 0.399201915 GPX1 -- unknown -- Glutathione peroxidase YKL071W YKL071W 0.1 12 0.3 0.0327 0.672276846 iYKL072W iYKLCdelta5 0.600280602 0.650023286 0.925838574 0.473412826 0.735195531 YKL071W -- unknown -- similarity to proteins of short-chain alcohol dehydrogenase familyexpression is regulated by Yap1p transcription factor YLL063C AYT1 0.1 15 0.3 0.0327 0.609370168 iYLL063C 0.580526775 0.431636686 0.478246858 AYT1 -- unknown -- similarity to acetyltransferases YLR234W TOP3 0.1 18 0.3 0.0327 0.240416913 iYLR233C 0.15565763 0.363556953 0.208024492 "TOP3 -- DNA replication -- DNA topoisomerase III, relaxes negatively (but not positively) supercoiled DNA" YMR052W FAR3 0.1 20 0.3 0.0327 0.628134808 iYMRCdelta10 YMRCdelta11 0.454431871 0.722393611 0.642697526 0.334031582 0.769416694 "FAR3 -- cell cycle, pheromone arrest -- pheromone-mediated cell cycle arrest" YMR084W YMR084W 0.1 20 0.3 0.0327 0.574252605 iYMR083W 0.384962052 0.690422985 0.318745632 "YMR084W -- unknown -- unknown function, YMR085W and YMR084W are possible parts of a pseudogene with similarity to Gfa1p" YMR159C APG16 0.1 15 0.3 0.0327 0.40039733 iYMR159C 0.257179042 0.530922609 0.16935224 APG16 -- autophagy -- Coiled-coil autophagyhas similarity to human Sin3 complex component SAP18 YMR245W YMR245W 0.1 20 0.3 0.0327 0.246235403 0.360587002 YMR245W -- unknown -- unknown function YMR290W-A 0.1 17 0.3 0.0327 0.677443607 0.10505962 YNL179C YNL179C 0.1 17 0.3 0.0327 0.16215593 iYNL179C-0 iYNL179C-1 0.342874268 0.926242596 0.197399819 0.198493551 0.797370332 YNL179C -- unknown -- unknown function YNR004W YNR004W 0.1 15 0.3 0.0327 0.732845065 iYNR003C 0.628936417 0.948124501 0.763564003 YNR004W -- unknown -- unknown function YNR073C YNR073C 0.1 20 0.3 0.0327 0.454103934 iYNR073C 0.523150397 0.675775606 YNR073C -- unknown -- similarity to E. coli D-mannonate oxidoreductaseYel070p and Ynr073p are identical proteins YOR019W YOR019W 0.1 21 0.3 0.0327 0.405069052 iYOR018W 0.151044196 0.472226656 0.119572756 "YOR019W -- unknown -- unknown function, contains a UspA ATP-binding domain" YOR135C YOR135C 0.1 17 0.3 0.0327 0.38817781 0.362979207 YOR135C -- unknown -- unknown function YOR386W PHR1 0.1 16 0.3 0.0327 0.362404245 iYOR385W 0.478770729 0.224820431 0.181448993 PHR1 -- DNA repair -- Deoxyribodipyrimidine photolyaseinvolved in light-dependent repair of pyrimidine dimers YPL171C OYE3 0.1 23 0.3 0.0327 0.633591004 iYPL171C 0.844024615 0.708549329 0.453232243 "OYE3 -- unknown -- NAPDH dehydrogenase (old yellow enzyme), isoform 3" YPL174C NIP100 0.1 18 0.3 0.0327 0.4225347 iYPL174C 0.481889484 0.43886672 0.621986341 "NIP100 -- nuclear protein targeting -- Mitotic spindle positioning protein, dynactin complex protein associated with the spindle" YPL197C YPL197C 0.1 20 0.3 0.0327 0.93060054 iYPL197C 0.537927615 0.48931193 0.363048683 "YPL197C -- unknown -- unknown function, questionable ORF" YPR001W CIT3 0.1 18 0.3 0.0327 0.243429577 iYPL001W CEN16 0.522842646 0.66236524 0.471872816 0.203266946 0.401205451 "CIT3 -- TCA cycle -- Citrate synthase, mitochondrial, converts acetyl-CoA and oxaloacetate into citrate plus CoA" YPR061C YPR061C 0.1 23 0.3 0.0327 0.260492799 iYPR061C 0.238698946 0.495371109 0.458014036 YPR061C -- unknown -- similarity to E. coli DnaJ and other DnaJ-like proteins YPR099C YPR099C 0.1 23 0.3 0.0327 0.11407974 0.038085255 YPR099C -- unknown -- unknown function YBL088C TEL1 0.3 63 0.2 0.0094 1 0.699033856 iYBL088C IntYBL087C 0.771712856 0.960251983 0.564373187 0.31580221 0.663786719 TEL1 -- telomere length regulation -- Phosphatidylinositol 3-kinase (PI kinase) homolog involved in controlling telomere length YEL072W YEL072W 0.2 32 0.2 0.0094 1 0.923172033 iYEL073C-0 iYEL073C-1 0.944282165 0.830189082 0.353956602 0.824282952 0.864806001 YEL072W -- unknown -- unknown function YNL025C SSN8 0.1 25 0.2 0.0094 1 0.527429815 iYNL025C SNR66 0.885775978 0.870942204 0.67193039 0.541990537 0.697309056 "SSN8 -- transcription -- Cyclin C homolog, component of RNA polymerase holoenzyme complex and Kornberg's mediator (SRB) subcomplex" YCR006C YCR006C 0.1 12 0.2 0.0094 1 0.604994579 iYCR006C tP(AGG)C 0.602675328 0.668327344 0.868339831 0.654030327 0.282320056 YCR006C -- unknown -- unknown function YIL055C YIL055C 0.1 26 0.2 0.0094 1 0.823714121 iYIL055C 0.977418181 0.424660814 0.322336049 YIL055C -- unknown -- unknown function YCR033W YCR033W 0.6 84 0.2 0.0094 0.641910412 iYCR032W 0.483335998 0.329278118 0.677893057 YCR033W -- unknown -- unknown function YDL234C GYP7 0.6 116 0.2 0.0094 0.445806609 iYDL234C 0.602977709 0.256594337 0.74179215 GYP7 -- vacuole inheritance -- GTPase-activating protein for Ypt7p YHL021C YHL021C 0.6 98 0.2 0.0094 0.502651202 iYHL021C 0.261400443 0.921034242 0.082023061 YHL021C -- unknown -- unknown function YMR191W YMR191W 0.6 108 0.2 0.0094 0.391938669 iYMR190C 0.250838832 0.710121663 0.188916673 YMR191W -- unknown -- unknown function YNR065C YNR065C 0.6 87 0.2 0.0094 0.447281744 0.476235552 YNR065C -- unknown -- similarity to Pep1p YBR212W NGR1 0.4 99 0.2 0.0094 0.105441565 iYBR211C 0.137976929 0.183479532 0.239493426 "NGR1 -- unknown -- Glucose-repressible RNA-binding protein, has 2 RNA recognition (RRM) domains and a glutamine-rich region" YBR225W YBR225W 0.4 87 0.2 0.0094 0.174909788 0.340566266 YBR225W -- unknown -- unknown function YJL155C FBP26 0.4 71 0.2 0.0094 0.191134085 iYJL155C 0.403364569 0.499113761 0.568875893 "FBP26 -- fructose metabolism -- Fructose-2,6-bisphosphatase" YKL224C YKL224C 0.4 88 0.2 0.0094 0.929540386 iYKL224C 0.94036254 0.425844704 0.538905133 YKL224C -- unknown -- Member of seripauperin (PAU) familysubtelomerically encoded YPL070W YPL070W 0.4 86 0.2 0.0094 0.153307011 iYPL071C 0.363290693 0.177816177 0.536960286 YPL070W -- unknown -- unknown function YPL159C YPL159C 0.4 81 0.2 0.0094 0.289351527 iYPL159C 0.507734389 0.46227269 0.668236233 YPL159C -- unknown -- unknown function YCL044C YCL044C 0.3 54 0.2 0.0094 0.109312756 iYCL044C 0.021858719 0.08926845 0.00178353 YCL044C -- unknown -- unknown function YIL144W TID3 0.3 51 0.2 0.0094 0.247146213 iYIL145C 0.320632837 0.343783428 0.357704403 "TID3 -- cytoskeleton -- spindle pole body with similarity to myosin heavy chain, possible coiled-coil" YOR062C YOR062C 0.3 64 0.2 0.0094 0.559945009 iYOR062C 0.452407721 0.575019952 0.740143839 YOR062C -- unknown -- unknown function YBR102C EXO84 0.2 55 0.2 0.0094 0.394616968 iYBR102C 0.469862486 0.644213887 0.425519818 EXO84 -- secretion -- Subunit of exocyst complex YBR297W MAL33 0.2 36 0.2 0.0094 0.473562463 iYBR296C-0 iYBR296C-1 0.84068749 0.438113363 0.855147646 0.501492297 0.29688747 "MAL33 -- maltose metabolism -- Maltose fermentation regulatory protein, has a Zn[2]-Cys[6] fungal-type binuclear cluster domain" YCL039W YCL039W 0.2 50 0.2 0.0094 0.417833208 iYCL040W 0.677456316 0.149447693 0.387546468 "YCL039W -- unknown -- unknown function, member of WD (WD-40) repeat family" YCR068W YCR068W 0.2 31 0.2 0.0094 0.874189813 iYCR067C 0.509386272 0.442935901 0.288108282 YCR068W -- unknown -- unknown function YCR081W SRB8 0.2 48 0.2 0.0094 0.453168139 iYCR079W 0.423723309 0.825857941 0.407084612 SRB8 -- transcription -- Component of RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex YDR082W STN1 0.2 35 0.2 0.0094 0.214662896 iYDR081C 0.258713476 0.556603774 0.251289075 "STN1 -- telomere length regulation -- telomere size regulation, associates with Cdc13p" YDR085C AFR1 0.2 41 0.2 0.0094 0.368033565 iYDR085C 0.077492075 0.760415004 0.233685569 AFR1 -- mating -- morphogenesis of mating projection YDR185C YDR185C 0.2 59 0.2 0.0094 0.527775446 iYDR185C 0.715402651 0.861851556 0.541581511 YDR185C -- unknown -- Putative member of intramitochondrial sorting protein family YDR216W ADR1 0.2 40 0.2 0.0094 0.6332036 iYDR215C 0.454536807 0.523623304 0.425059142 ADR1 -- transcription -- Zinc-finger transcription factor involved in regulation of ADH2 and peroxisomal genes YDR221W YDR221W 0.2 42 0.2 0.0094 0.308961572 0.724430182 YDR221W -- unknown -- similarity to the beta subunit of human glucosidase II YDR425W YDR425W 0.2 48 0.2 0.0094 0.197925709 iYDR424C 0.098426469 0.448992853 0.105590062 YDR425W -- unknown -- unknown function YGR006W PRP18 0.2 43 0.2 0.0094 0.468036357 iYGR005C 0.475248393 0.644643461 0.904879454 PRP18 -- mRNA splicing -- U5 snRNA-associated protein involved exclusively in the second step of pre-mRNA splicing YHR004C NEM1 0.2 40 0.2 0.0094 0.659455409 iYHR004C 0.546378781 0.856429262 0.460049766 NEM1 -- nuclear organization and biogenesis -- nuclear morphology YHR137W ARO9 0.2 54 0.2 0.0094 0.797516841 iYHR136C 0.092128744 0.848679338 0.078066914 ARO9 -- aromatic amino acid metabolism -- Aromatic amino acid aminotransferase II YHR155W YHR155W 0.2 53 0.2 0.0094 0.273373136 iYHR154W 0.290926185 0.793095104 0.741552956 YHR155W -- unknown -- similarity to Sip3p YHR156C YHR156C 0.2 41 0.2 0.0094 0.495754508 iYHR156C 0.318210763 0.455165692 0.549790525 YHR156C -- unknown -- unknown function YJL066C YJL066C 0.2 30 0.2 0.0094 0.267708958 iYJL066C 0.620248149 0.489634589 0.496652416 YJL066C -- unknown -- unknown function YJL082W IML2 0.2 39 0.2 0.0094 0.296007624 iYJL083W 0.407706203 0.555466879 0.230073056 "IML2 -- plasmid maintenance (putative) -- unknown function, has a role in stability of artificial minichromosomes" YKL124W SSH4 0.2 39 0.2 0.0094 0.425759556 iYKL125W 0.44695505 0.590142776 0.760127883 SSH4 -- unknown -- Suppressor of shr3 and overproduction confers resistance to immunosuppressive drug leflunomide YLR011W YLR011W 0.2 54 0.2 0.0094 0.282617521 iYLR010C iYLRCsigma1 0.354397641 0.19087414 0.743889651 0.353770545 0.556341719 YLR011W -- unknown -- similarity to E. coli 20.4 KD unknown function YLR142W PUT1 0.2 35 0.2 0.0094 0.432796343 iYLR141W 0.13979747 0.473642119 0.09553503 "PUT1 -- proline utilization -- Proline oxidase (proline dehydrogenase), first step in synthesis of glutamate from proline" YLR431C YLR431C 0.2 31 0.2 0.0094 0.2604541 iYLR431C 0.623571011 0.408705669 0.449161426 YLR431C -- unknown -- unknown function YMR041C YMR041C 0.2 40 0.2 0.0094 0.330774257 iYMR041C itF(GAA)M 0.513785606 0.442094087 0.596978558 0.612735543 0.305477132 YMR041C -- unknown -- unknown function YMR114C YMR114C 0.2 46 0.2 0.0094 0.394562882 iYMR114C 0.605783542 0.448514614 0.476324917 YMR114C -- unknown -- unknown function YMR196W YMR196W 0.2 40 0.2 0.0094 0.381677503 iYMR195W 0.206534582 0.438154782 0.48314116 YMR196W -- unknown -- unknown function YNL127W YNL127W 0.2 54 0.2 0.0094 0.046868554 iYNL128W 0.200659217 0.314733593 0.214711569 YNL127W -- unknown -- weak similarity to Fus2p YNL218W YNL218W 0.2 44 0.2 0.0094 0.594609099 iYNL219C 0.498269551 0.86528999 0.686408106 YNL218W -- unknown -- similarity to E. coli DNA polymerase III gamma and tau subunits YNL295W YNL295W 0.2 34 0.2 0.0094 0.183542747 iYNL296W 0.125004659 0.341107617 0.247972288 YNL295W -- unknown -- unknown function YNR002C YNR002C 0.2 31 0.2 0.0094 0.659240134 iYNR002C 0.640172837 0.705816997 0.708431903 "YNR002C -- unknown -- unknown function, has strong similarity to Ycr010p and Ydr384p" YNR007C AUT1 0.2 46 0.2 0.0094 0.028804578 iYNR007C 0.195260294 0.303057191 0.106830887 AUT1 -- autophagy -- autophagocytosis during starvation YOL023W IFM1 0.2 34 0.2 0.0094 0.370370217 iYOL024W 0.692339178 0.771433375 0.679420719 "IFM1 -- protein synthesis -- Mitochondrial translation initiation factor 2, homologous to EF2" YOL116W MSN1 0.2 42 0.2 0.0094 0.482689758 iYOL117W 0.518411361 0.66790203 0.192958427 "MSN1 -- nutrient sensing -- Transcriptional activator for genes regulated through Snf1p, involved in response to nutrient limitation" YPL109C YPL109C 0.2 42 0.2 0.0094 0.132309703 iYPL109C 0.336404288 0.40758943 0.594253791 YPL109C -- unknown -- unknown function YPL110C YPL110C 0.2 54 0.2 0.0094 0.437666727 iYPL110C 0.371454984 0.148759609 0.551181738 YPL110C -- unknown -- similarity to Pho81p YPL119C DBP1 0.2 33 0.2 0.0094 0.097195472 iYPL119C 0.250373451 0.276886366 0.148276146 DBP1 -- mRNA processing -- ATP-dependent RNA helicase of DEAD box familysuppressor of spp81/ded1 YPL152W RRD2 0.2 48 0.2 0.0094 0.27603541 iYPL153C 0.564158468 0.620938921 0.511807784 RRD2 -- drug resistance -- rapamycin sensitivity YPL194W DDC1 0.2 42 0.2 0.0094 0.195989283 iYPL195W 0.444063489 0.152603075 0.325820303 "DDC1 -- cell cycle, checkpoint -- DNA damage checkpoint proteindelays the cell cycle at the G1/S boundary in response to UV irradiation, member of RAD24 epistasis group" YPL264C YPL264C 0.2 47 0.2 0.0094 0.128739692 iYPL264C 0.060316296 0.207197764 0.016247379 YPL264C -- unknown -- unknown function YPR002W PDH1 0.2 36 0.2 0.0094 0.165030118 iYPR001W 0.434870151 0.29134178 0.262568913 PDH1 -- proionate metabolism (putative) -- Protein possibly involved in propionate utilization YPR077C YPR077C 0.2 37 0.2 0.0094 0.711786959 0.492059574 YPR077C -- unknown -- unknown function YAR060C YAR060C 0.1 27 0.2 0.0094 0.782798387 iYAR060C 0.558307011 0.640582572 0.898960364 "YAR060C -- unknown -- identical to Yhr212p, has a predicted mitochondrial transit peptide" YBR027C YBR027C 0.1 18 0.2 0.0094 0.576292417 iYBR027C 0.510195924 0.770527603 0.19964913 YBR027C -- unknown -- unknown function YBR089W YBR089W 0.1 11 0.2 0.0094 0.406765217 0.686809617 "YBR089W -- unknown -- unknown function, questionable ORF" YBR132C AGP2 0.1 36 0.2 0.0094 0.421364385 iYBR132C 0.177204283 0.710277298 0.371024434 "AGP2 -- transport -- Plasma membrane carnitine transporter, required for the carnitine-depenent pathway for transport of acetyl-CoA from peroxisomes to mitochondria, member of amino acid-polyamine-choline (APC) family of membrane transporters" YBR226C YBR226C 0.1 35 0.2 0.0094 0.780922518 0.384118117 YBR226C -- unknown -- unknown function YCL021W 0.1 22 0.2 0.0094 YCL026C-A 0.1 22 0.2 0.0094 0.393608721 iYCL026C-A 0.557252532 0.705751666 0.89273743 YCL053C 0.1 23 0.2 0.0094 YCR038C BUD5 0.1 23 0.2 0.0094 0.926788346 iYCR038C 0.941032342 0.079728651 0.033138402 "BUD5 -- bud site selection -- GTP/GDP exchange factor for Rsr1p/Bud1p involved in bud site selection, mutants bud at random sites" YDL094C YDL094C 0.1 19 0.2 0.0094 0.664358932 0.569562819 YDL094C -- unknown -- unknown function YDL204W YDL204W 0.1 25 0.2 0.0094 0.088657952 iYDL205C 0.271826407 0.214631002 0.261355695 YDL204W -- unknown -- unknown function YDL214C YDL214C 0.1 19 0.2 0.0094 iYDL214C 0.550823558 0.556353498 YDL214C -- unknown -- Serine/threonine protein kinase with similarity members of NPR1 subfamily YDR008C 0.1 16 0.2 0.0094 0.128788488 iYDR008C 0.574483479 0.066558859 0.626522546 YDR132C YDR132C 0.1 16 0.2 0.0094 0.316476615 iYDR132C 0.411736979 0.632452465 0.319345018 "YDR132C -- unknown -- unknown function, putative pseudogene" YDR255C YDR255C 0.1 29 0.2 0.0094 0.653626266 iYDR255C 0.197248843 0.708379888 0.216503993 YDR255C -- unknown -- unknown function YGL158W RCK1 0.1 16 0.2 0.0094 0.241044532 iYGL159W YGLWtau2 0.620957204 0.770583256 0.623961162 0.589472795 0.791779729 "RCK1 -- unknown -- Serine/threonine protein kinase with similarity to Cmk1p, Cmk2p, and Cmk3p" YGL175C SAE2 0.1 14 0.2 0.0094 0.287680104 iYGL175C 0.347700356 0.467118915 0.624488503 "SAE2 -- meiosis, recombination -- meiotic recombination" YGL227W VID30 0.1 22 0.2 0.0094 0.188237045 iYGL228W 0.849663463 0.498724595 0.445733564 "VID30 -- signaling? -- unknown function, null mutant is starvation-sensitive and exhibits vacuolar degradation of cytosolic proteins" YGR043C YGR043C 0.1 19 0.2 0.0094 0.390695073 iYGR043C-0 iYGR043C-1 0.254708366 0.590265326 0.850160454 0.379793748 0.589884696 "YGR043C -- unknown -- unknown function, may be involved in signal transductionhas strong similarity to Tal1p" YGR188C BUB1 0.1 23 0.2 0.0094 0.311914656 iYGR188C iYGRWdelta31 0.474456104 0.742257072 0.393695132 0.695617145 0.549281632 "BUB1 -- cell cycle, checkpoint -- Serine/threonine protein kinase and checkpoint cell cycle arrest in response to loss of microtubule function" YHL012W YHL012W 0.1 16 0.2 0.0094 0.671091191 iYHL013C 0.294803303 0.939501492 0.02997076 YHL012W -- unknown -- similarity to UTP glucose-1-phosphate uridylyltransferase YHL042W YHL042W 0.1 15 0.2 0.0094 0.490583931 iYHL043W 0.445374824 0.806243446 0.353948288 "YHL042W -- unknown -- similarity to subtelomerically-encoded proteins such as Cos5p, Ybr302p, Cos3p, Cos1p, Cos4p, Cos8p, Cos6p, Cos9p" YHR101C BIG1 0.1 38 0.2 0.0094 0.795087367 iYHR101C 0.123080693 0.895131684 0.396199252 "BIG1 -- signaling (putative) -- normal growth on glucose, suppressor of rot1 rot2 synthetic lethality" YHR173C YHR173C 0.1 24 0.2 0.0094 0.51286281 iYHR173C 0.846153169 0.628135839 0.591965096 YHR173C -- unknown -- unknown function YIL082W 0.1 15 0.2 0.0094 0.195142003 iYIL083C 0.288970845 0.167641326 0.702873105 YIL099W SGA1 0.1 21 0.2 0.0094 0.33023878 iYIL100W 0.393428677 0.551139636 0.120289149 "SGA1 -- sporulation -- Glucoamylase (glucan-alpha-1,4-glucosidase), sporulation-specific" YIL168W SDL1 0.1 18 0.2 0.0094 0.118739449 iYIL169C-0 iYIL169C-1 0.819254512 0.767069585 0.28045809 0.759668063 0.597491958 "SDL1 -- gluconeogenesis -- Serine dehydratase, converts serine to pyruvate and ammonia for gluconeogenesis" YIR032C DAL3 0.1 21 0.2 0.0094 0.709795683 iYIR032C 0.303295619 0.828616352 0.272404614 DAL3 -- purine metabolism -- Ureidoglycolate hydrolaseinvolved in utilization of purines as nitrogen sources by converting (-)-ureidoglycolate + H20 to glyoxylate + 2 NH3 + CO2 YJL015C YJL015C 0.1 23 0.2 0.0094 0.742842372 0.888340327 "YJL015C -- unknown -- unknown function, overlaps with YJL016W" YJL103C YJL103C 0.1 22 0.2 0.0094 0.149137684 iYJL103C 0.224583493 0.48901656 0.106550634 "YJL103C -- unknown -- similarity to transcription factors, has Zn[2]-Cys[6] fungal-type binuclear cluster domain in the N-terminal region" YJL120W YJL120W 0.1 22 0.2 0.0094 0.561990889 0.51394052 YJL120W -- unknown -- unknown function YJR162C YJR162C 0.1 16 0.2 0.0094 0.998669655 0.033979734 YJR162C -- unknown -- similarity to subtelomerically-encoded proteins including Gin11p and Ykl225p YKR019C IRS4 0.1 21 0.2 0.0094 0.093922925 iYKR019C 0.126674289 0.14709993 0.329347077 IRS4 -- silencing (rDNA) -- silencing of ribosomal DNA YKR097W PCK1 0.1 30 0.2 0.0094 0.374073849 iYKR096W 0.381406378 0.93055108 0.224577648 "PCK1 -- TCA cycle -- Phosphoenolpyruvate carboxykinase (ATP), rate limiting gluconeogenic enzyme" YKR103W YKR103W 0.1 22 0.2 0.0094 0.350603206 iYKR102W-0 iYKR102W-1 0.70674337 0.590835963 0.283128069 0.86009577 0.372305319 YKR103W -- unknown -- Member of ATP-binding cassette (ABC) superfamilypossible pseudogene YLL033W YLL033W 0.1 23 0.2 0.0094 0.452929382 iYLL034C 0.206500119 0.523234201 0.220354126 YLL033W -- unknown -- unknown function YLR054C YLR054C 0.1 20 0.2 0.0094 0.458778531 iYLR054C 0.41433358 0.753979857 0.591078067 YLR054C -- unknown -- unknown function YLR156W YLR156W 0.1 29 0.2 0.0094 0.59271237 iYLR155C-0 iYLR155C-A 0.081218203 0.169040735 0.578541261 0.441736548 0.233778303 YLR156W -- unknown -- unknown function YLR213C CRR1 0.1 18 0.2 0.0094 0.345824881 iYLR213C 0.897660006 0.248363927 0.601580879 CRR1 -- unknown -- Sporulation specific similarity to Crh1p cell wall protein YLR269C YLR269C 0.1 20 0.2 0.0094 0.114629119 0.138904574 YLR269C -- unknown -- unknown function YLR365W YLR365W 0.1 17 0.2 0.0094 0.552407242 iYLR364W 0.666558415 0.767438148 0.878930567 "YLR365W -- unknown -- unknown function, possible pseudogene" YLR453C RIF2 0.1 26 0.2 0.0094 0.945683441 iYLR453C 0.743011893 0.924298527 0.76579117 RIF2 -- silencing -- Rap1p-interacting factorinvolved with Rap1p in transcriptional silencing and telomere length regulation YML095C RAD10 0.1 23 0.2 0.0094 0.201947401 iYML095C 0.128959575 0.489035088 0.055508618 "RAD10 -- DNA repair -- Component of nucleotide excision repairosome, homolog of mammalian ERCC-1 gene product" YMR007W YMR007W 0.1 23 0.2 0.0094 0.515060486 iYMR006C 0.304412494 0.842852315 0.549145988 YMR007W -- unknown -- tunicamycin sensitivity YMR025W YMR025W 0.1 16 0.2 0.0094 0.263458652 iYMR024W 0.404815221 0.425763483 0.459957765 YMR025W -- unknown -- unknown function YMR137C PSO2 0.1 29 0.2 0.0094 0.320154205 iYMR137C 0.396282689 0.333120511 0.162930474 PSO2 -- DNA repair -- DNA repair protein for interstrand crosslinks YNL077W YNL077W 0.1 32 0.2 0.0094 0.803493021 iYNL078W 0.588815377 0.56148473 0.735367899 YNL077W -- unknown -- induced by cell stresssimilar to E. coli DnaJ and other DnaJ-like proteins YNL195C YNL195C 0.1 20 0.2 0.0094 0.273925102 iYNL195C 0.582092044 0.531364725 0.468783209 "YNL195C -- unknown -- unknown function, induced during aerobic growth" YNL203C YNL203C 0.1 19 0.2 0.0094 0.16468185 0.244763132 YNL203C -- unknown -- weak similarity to Bacillus subtilis CDPdiacylglycerol--serine O-phosphatidyltransferase YNL210W MER1 0.1 16 0.2 0.0094 0.338689368 iYNL211C 0.431966882 0.811320755 0.490496174 "MER1 -- meiosis, MER2 mRNA splicing -- Meiosis-specific splicing of REC107 mRNA and mRNA for at least one other gene" YNL260C YNL260C 0.1 23 0.2 0.0094 0.782750735 iYNL260C 0.71524368 0.77891488 0.395663025 YNL260C -- unknown -- Essential unknown function YOL114C YOL114C 0.1 27 0.2 0.0094 0.422633273 iYOL114C 0.200373468 0.668047433 0.349978741 YOL114C -- unknown -- similarity to human DS-1 protein YOR137C YOR137C 0.1 29 0.2 0.0094 0.271008906 iYOR137C 0.59750703 0.661134386 0.504788508 YOR137C -- unknown -- unknown function YOR173W YOR173W 0.1 21 0.2 0.0094 0.613451214 iYOR172W 0.34273353 0.462213986 0.293375898 YOR173W -- unknown -- unknown function YOR318C YOR318C 0.1 28 0.2 0.0094 0.423710228 iYOR318C 0.388225874 0.456265943 0.133580705 YOR318C -- unknown -- unknown function YOR333C YOR333C 0.1 21 0.2 0.0094 0.015354459 0.120817844 YOR333C -- unknown -- unknown function YPL035C YPL035C 0.1 19 0.2 0.0094 0.16115191 0.256908555 YPL035C -- unknown -- unknown function YPR087W YPR087W 0.1 39 0.2 0.0094 0.400281305 iYPR086W 0.040437334 0.140286513 0.050351126 YPR087W -- unknown -- unknown function YPR184W YPR184W 0.1 28 0.2 0.0094 0.105890385 iYPR183W 0.342966298 0.139381244 0.063402436 YPR184W -- unknown -- Glycogen debranching enzyme YKR102W FLO10 0.2 45 0.1 0 1 0.263718186 iYKR101W-0 iYKR101W-1 0.933569401 0.624687518 0.463447725 0.548842777 0.469934774 FLO10 -- unknown -- similarity to flocculation protein Flo1p YIL054W YIL054W 0.1 46 0.1 0 1 0.964728186 iYIL055C 0.977418181 0.879793748 0.322336049 YIL054W -- unknown -- unknown function YNR069C YNR069C 0.1 27 0.1 0 1 0.820312639 iYNR069C-0 iYNR069C-1 0.971946364 0.883135635 0.733725901 0.896442495 0.27326586 "YNR069C -- unknown -- similarity to Bul1p ubiquitin ligase binding protein, may be a pseudogene or separated from YNR068C by sequencing errors" YGR127W YGR127W 0.3 112 0.1 0 0.501585962 iYGR126W 0.355780354 0.980827779 0.259457302 YGR127W -- unknown -- similarity to mouse T10 protein PIR YJL088W ARG3 0.3 77 0.1 0 0.446207352 iYJL089W 0.336039889 0.844426974 0.14022398 "ARG3 -- arginine biosynthesis -- Ornithine carbamyltransferase, catalyzes the sixth step in the arginine biosynthesis pathway" YBL049W YBL049W 0.2 62 0.1 0 0.575570737 iYBL050W 0.847143356 0.661687631 0.749401437 YBL049W -- unknown -- unknown function YCR024C YCR024C 0.2 68 0.1 0 0.577764374 iYCR024C 0.723467166 0.720915243 0.091620112 "YCR024C -- protein synthesis -- Asparaginyl-tRNA synthetase, mitochondrial" YEL011W GLC3 0.2 80 0.1 0 0.461733631 iYEL012W 0.2860866 0.591859537 0.529005184 "GLC3 -- cell wall biogenesis -- alpha-1,4-glucan branching enzyme" YKR091W SRL3 0.2 80 0.1 0 0.38138249 iYKR090W 0.551052101 0.404795126 0.372272641 SRL3 -- unknown -- unknown function YLL052C 0.2 60 0.1 0 0.60346793 iYLL052C 0.338105859 0.354668795 0.424105704 YNL057W YNL057W 0.2 48 0.1 0 0.298805026 0.274774423 YNL057W -- unknown -- unknown functionquestionable ORF YNL230C ELA1 0.2 85 0.1 0 0.177756192 iYNL230C 0.625814451 0.439701079 0.670081471 "ELA1 -- transcription (putative) -- Elongin A transcription elongation factor, contains an F-box domain" YPL005W YPL005W 0.2 74 0.1 0 0.59046213 iYPL006W 0.327769325 0.407741421 0.28858739 YPL005W -- unknown -- unknown function YPL123C RNY1 0.2 54 0.1 0 0.422369527 iYPL123C 0.500565748 0.39249568 0.561372706 RNY1 -- unknown -- Ribonuclease of ribonuclease T2 family YPR158W YPR158W 0.2 96 0.1 0 0.435780817 iYPR157W 0.237625737 0.542056075 0.272800516 YPR158W -- unknown -- unknown function YBR148W YSW1 0.1 23 0.1 0 0.348690441 iYBR147W 0.413251191 0.337415404 0.381114605 YSW1 -- unknown -- Spore-specific protein YCL007C CWH36 0.1 38 0.1 0 0.279117856 iYCL007C SNR43 0.751388435 0.750580437 0.103431252 0.395740905 0.402428372 CWH36 -- cell wall biogenesis -- generation of mannolayer of cell wall YCL023C YCL023C 0.1 27 0.1 0 0.889185702 0.416851806 "YCL023C -- unknown -- unknown function, may be required for resistance to certain drugs" YDL243C AAD4 0.1 39 0.1 0 0.738801809 iYDL243C 0.382350274 0.723942538 0.580625437 "AAD4 -- unknown -- Putative aryl-alcohol dehydrogenase, may participates in late steps of degradation of aromatic compounds that arise from the degradation of lignocellulose" YDR043C NRG1 0.1 64 0.1 0 0.795612757 iYDR043C-0 iYDR043C-1 0.37678677 0.30698206 0.733593242 0.329945269 0.797566746 "NRG1 -- unknown -- Transcriptional repressor involved in STA1 glucose repression, suppressor of snf mutations, has two tandem C2H2-type zinc fingers" YDR070C YDR070C 0.1 55 0.1 0 0.733213866 iYDR070C 0.548092013 0.843941347 0.4957756 YDR070C -- unknown -- unknown function YDR250C YDR250C 0.1 55 0.1 0 0.272791048 iYDR250C 0.320325545 0.505726383 0.461582196 YDR250C -- unknown -- unknown function YDR254W CHL4 0.1 21 0.1 0 0.546942221 iYDR253C 0.275739997 0.797747291 0.247725796 "CHL4 -- mitosis, chromosome segregation -- Chromosome segregation stable maintenance and transmission of normal and artificial chromosomes" YDR403W DIT1 0.1 31 0.1 0 0.710018465 iYDR402C 0.305355066 0.817998711 0.209486166 "DIT1 -- sporulation, spore wall biogenesis -- First enzyme in the pathway for biosynthesis of dityrosine in the outer layer of spore wallexpressed late (10-16 hr) in sporulation" YER135C YER135C 0.1 19 0.1 0 0.862529912 iYER135C itV(AAC)E1 0.799137616 0.35467646 0.709896249 0.827442056 0.383560539 YER135C -- unknown -- unknown function YER184C YER184C 0.1 39 0.1 0 0.24940202 iYER184C 0.497586884 0.568685972 0.695211492 "YER184C -- unknown -- similarity to transcription factors, has Zn[2]-Cys[6] fungal-type binuclear cluster domain in the N-terminal region" YGL052W YGL052W 0.1 25 0.1 0 0.738578872 iYGL053W 0.240403883 0.787705446 0.336552275 YGL052W -- unknown -- unknown function YGR114C YGR114C 0.1 38 0.1 0 0.25182108 0.214599527 "YGR114C -- unknown -- unknown function, questionable ORF" YIL028W YIL028W 0.1 56 0.1 0 0.78264274 iYIL029C 0.362363834 0.864485235 0.649633835 "YIL028W -- unknown -- unknown function, possible pseudogene" YIL071C YIL071C 0.1 35 0.1 0 0.510016589 iYIL071C 0.584523708 0.601836932 0.511233873 YIL071C -- unknown -- unknown function YIL160C POT1 0.1 33 0.1 0 0.515616069 iYIL160C 0.072833161 0.836727835 0.10771003 "POT1 -- fatty acid metabolism -- 3-Ketoacyl-CoA thiolase, peroxisomal (acetyl-CoA acyltransferase), catalyzes last step of peroxisomal fatty acid beta-oxidation" YIR030C DCG1 0.1 15 0.1 0 0.519062162 iYIR030C 0.435704402 0.611182726 0.195047189 DCG1 -- unknown -- Protein possibly involved in cell wall structure or biosynthesis YJL032W YJL032W 0.1 19 0.1 0 0.548334614 iYJL033W 0.671091095 0.6742542 0.674050983 YJL032W -- unknown -- unknown functionquestionable ORF YJL075C YJL075C 0.1 26 0.1 0 0.390001726 iYJL075C 0.807356167 0.448818262 0.503222688 YJL075C -- unknown -- unknown functionquestionable ORF YJR036C HUL4 0.1 31 0.1 0 0.086177932 0.380893607 HUL4 -- unknown -- Putative ubiquitin-protein ligase YKL086W YKL086W 0.1 40 0.1 0 0.681290225 iYKL087C 0.586220757 0.498403831 0.674760023 YKL086W -- unknown -- weak similarity to Rhodobacter sphaeroides bchY chlorophyllide reductase (chlorin reductase) subunit YKR005C YKR005C 0.1 21 0.1 0 0.675331796 iYKR005C 0.137102675 0.916187901 0.121156534 YKR005C -- unknown -- unknown function YLR217W YLR217W 0.1 37 0.1 0 0.546731483 0.673058331 YLR217W -- unknown -- unknown function YLR334C YLR334C 0.1 25 0.1 0 0.988504281 iYLRWdelta20 itE(UUC)L 0.931203095 0.793918361 0.733280128 0.518373824 0.66419295 YLR334C -- unknown -- unknown function YML084W YML084W 0.1 19 0.1 0 0.694649671 iYML085C 0.562090283 0.539114497 0.569403371 YML084W -- unknown -- unknown function YML118W YML118W 0.1 27 0.1 0 0.194760293 iYML119W 0.367158242 0.332741792 0.428651237 YML118W -- unknown -- unknown function YMR018W YMR018W 0.1 57 0.1 0 0.515505826 iYMR017W 0.120887303 0.70015634 0.095999301 YMR018W -- unknown -- similarity to Pex5p/Pas10p YNL093W YPT53 0.1 23 0.1 0 0.365816196 iYNL094W 0.203189555 0.449723847 0.189965314 "YPT53 -- endocytosis -- GTP-binding endocytosis and transport of proteins to the vacuole, member of rab family in the ras superfamily" YNR077C YNR077C 0.1 31 0.1 0 0.994819492 YNR077C -- unknown -- unknown function YOR178C GAC1 0.1 29 0.1 0 0.700443631 iYOR178C-0 iYOR178C-1 0.488610079 0.397239697 0.267907058 0.448695795 0.290183559 GAC1 -- glycogen metabolism -- Regulatory subunit for protein serine/threonine phosphatase Glc7p YOR379C YOR379C 0.1 20 0.1 0 0.484368558 iYOR379C 0.195319815 0.705734243 0.125802636 YOR379C -- unknown -- unknown function YPL166W YPL166W 0.1 27 0.1 0 0.388117667 iYPL167C 0.823782569 0.502445842 0.878842264 YPL166W -- unknown -- unknown function YPL191C YPL191C 0.1 22 0.1 0 0.583211915 iYPL191C 0.096765762 0.021848603 YPL191C -- unknown -- unknown function YGR177C ATF2 0.6 1 0.945740749 iYGR177C 0.613824059 0.841036465 0.677692751 ATF2 -- acetate ester biosynthesis -- Sterol O-acetyltransferaseacetylates certain toxic steroids such as pregnenolone to render them excretable YHL038C CBP2 0.6 1 0.944675191 iYHL038C 0.903132757 0.745457722 0.013741463 "CBP2 -- mRNA splicing, COB mRNA -- splicing of COB aI5 intron and for efficient splicing of 21S mitochondrial rRNA (LSU) intron" YGL141W HUL5 0.6 1 0.527758197 iYGL142C 0.977497167 0.527829499 0.122274336 HUL5 -- unknown -- Putative ubiquitin-protein ligase YJR059W PTK2 0.6 1 0.913919487 iYJR058C 0.983866033 0.344518835 0.144737925 PTK2 -- polyamine transport -- Serine/threonine protein kinase required for high-affinity polyamine transport YJR140C HIR3 0.4 1 0.937968193 iYJR140C 0.56016081 0.516052721 0.301401869 HIR3 -- transcription -- Histone transcription regulator YOL161C YOL161C 0.3 1 0.921578331 iYOL161C-0 iYOL161C-1 0.649630918 0.526782697 0.124742862 YOL161C -- unknown -- Member of seripauperin (PAU) familysubtelomerically-encoded YGL083W SCY1 0.3 1 0.553860005 iYGL084C 0.945305622 0.72048054 0.532003192 SCY1 -- unknown -- suppression of a GTPase mutant YAL034C YAL034C 0.2 1 0.978858214 iYAL034C 0.992893737 0.428109713 0.673907677 YAL034C -- unknown -- unknown function YKL178C STE3 0.1 1 0.94114454 0.95385552 "STE3 -- mating -- Pheromone a-factor G protein-coupled receptor (GPCR), member of GPCR or seven transmembrane segments (7-TMS) superfamily" YMR224C MRE11 0.1 1 0.915907064 iYMR224C 0.96405105 0.788273065 0.319285897 "MRE11 -- meiosis, recombination -- Single-stranded endonuclease and double-stranded exonuclease required for double strand break repair and meiotic recombination" YLR164W YLR164W 21 1 0.352609242 iYLR163C 0.517843662 0.67260899 0.756664006 YLR164W -- unknown -- strong similarity to Sdh4p YNL309W STB1 14 1 0.182426902 0.104210342 "STB1 -- unknown -- Sin3p-binding protein, involved in transcription regulation at Start in the absence of Cln3p" YDL186W YDL186W 1 0.970609726 0.403102664 YDL186W -- unknown -- unknown function YGL007W YGL007W 1 0.978744431 iYGL008C 0.757011612 0.336371703 0.143545117 YGL007W -- unknown -- unknown functionquestionable ORF YGL074C YGL074C 1 0.968592774 0.485412299 YGL074C -- unknown -- unknown function YIR014W YIR014W 1 0.939582329 iYIR013C 0.746523032 0.892976856 0.634078212 YIR014W -- unknown -- unknown function YIR015W RPR2 20 1 0.961746963 iYIR014W 0.907458039 0.183209041 0.444647897 "RPR2 -- tRNA processing -- Subunit of RNase P, which is responsible for pre-tRNA processing, sole protein subunit of RNase P that is not also a subunit of RNase MRP" YKL031W YKL031W 1 0.973206695 iYKL032C 0.899806076 0.124002304 0.165685246 YKL031W -- unknown -- unknown function YLR004C YLR004C 15 1 0.939797383 iYLR004C 0.857989891 0.752359442 0.334814449 YLR004C -- unknown -- similarity to Dal5p and other members of allantoate permease family of major facilitator superfamily (MFS) YLR111W YLR111W 1 0.963283828 iYLR110C 0.910306302 0.491620112 0.321599115 YLR111W -- unknown -- unknown function YCR025C YCR025C 1 0.995238557 iYCR025C 0.978338989 0.609260305 0.559378021 YCR025C -- unknown -- unknown function YCR103C YCR103C 13 1 0.937157814 iYCR103C 0.944820843 0.871418588 0.759135275 YCR103C -- unknown -- unknown function YDL169C UGX2 30 1 0.758612089 iYDL169C 0.962482739 0.416210119 0.820590583 UGX2 -- unknown -- unknown function YDR040C ENA1 1 0.703868518 iYDR040C 0.973324248 0.334320744 0.397645601 "ENA1 -- transport -- P-type ATPase involved in Na+ and Li+ efflux, required for Na+ tolerance" YEL008W YEL008W 25 1 0.994747846 iYEL009C 0.935478602 0.092168869 0.203351955 YEL008W -- unknown -- growth in high salt YEL035C UTR5 1 0.989438072 iYEL035C 0.954231369 0.564617906 0.347897638 UTR5 -- unknown -- unknown function YER033C ZRG8 30 1 0.441676117 iYER033C 0.926078538 0.453444496 0.129172674 ZRG8 -- unknown -- unknown function YFL015C YFL015C 1 0.982384905 iYFL015C 0.962757269 0.148463945 0.294028273 YFL015C -- unknown -- unknown function YFL051C YFL051C 1 0.368053448 iYFL051C-0 iYFL051C-1 0.434731635 0.94103438 0.776315789 0.03617467 0.231507623 YFL051C -- unknown -- similarity to Flo1p family of proteins YGL258W YGL258W 1 0.932451085 iYGL259W-0 iYGL259W-1 0.932255137 0.98721062 0.858784047 0.451579117 0.23930787 YGL258W -- unknown -- unknown function YHL045W YHL045W 1 0.935282198 iYHL046C 0.940629956 0.526667741 0.389762404 YHL045W -- unknown -- unknown function YHR096C HXT5 1 0.780498685 iYHR096C 0.97512235 0.459466 0.563564552 HXT5 -- transport -- member of hexose transporter family of major facilitator superfamily (MFS) YJL027C YJL027C 1 0.952514964 iYJL027C 0.954392896 0.35177063 0.496996626 YJL027C -- unknown -- unknown function YJL028W YJL028W 1 0.969274472 iYJL029C itM(CAU)J1 0.87415968 0.939603142 0.304987005 0.572799871 0.589360587 YJL028W -- unknown -- unknown function YJL089W SIP4 34 1 0.857653812 iYJL090C 0.975509344 0.72417154 0.577893057 "SIP4 -- glucose derepression -- Transcriptional activator of gluconeogenic genes through CSRE elementsactivated by Snf1p kinase, possesses a Zn[2]-Cys[6] fungal-type binuclear cluster domain" YLR255C YLR255C 1 0.956141784 iYLR255C 0.923474956 0.117400419 0.12901318 YLR255C -- unknown -- unknown function YLR400W YLR400W 1 0.998561625 iYLR399C 0.999391224 0.487596087 0.951762523 YLR400W -- unknown -- unknown function YLR402W YLR402W 17 1 0.983666164 iYLR401C 0.984731152 0.511494716 0.352665968 YLR402W -- unknown -- unknown function YNR070W YNR070W 19 1 0.651581403 iYNR069C-0 iYNR069C-1 0.971946364 0.883135635 0.485714286 0.896442495 0.27326586 "YNR070W -- unknown -- Probable multidrug resistance ATP-binding cassette (ABC) family, has similarity to Snq2p, Pdr5p and Candida albicans Cdr1p" YOR100C CRC1 20 1 0.946631959 iYOR100C 0.957059997 0.500241702 0.14051332 "CRC1 -- transport -- Mitochondrial carnitine carrier, member of mitochondrial carrier (MCF) family" YOR343C YOR343C 14 1 0.963895008 iYOR343C YORWdelta22 0.954845195 0.759095889 0.350789558 0.31372865 0.332162809 YOR343C -- unknown -- unknown function YOR387C YOR387C 1 0.799294058 iYOR387C-0 iYOR387C-1 0.954936245 0.949414751 0.453632848 0.636312849 0.442936951 YOR387C -- unknown -- unknown function YPL017C YPL017C 22 1 0.94614079 iYPL017C 0.983360545 0.472783536 0.179478906 YPL017C -- unknown -- similarity to Lpd1p YPL189W GUP2 1 0.867419014 iYPL190C 0.933818228 0.362760185 0.302875244 GUP2 -- unknown -- Putative glycerol transporter involved in active glycerol uptake YPR030W CSR2 20 1 0.803136886 iYPR029C 0.972814298 0.479552374 0.657417117 CSR2 -- unknown -- unknown function YLR391W 8.5 YCL050C APA1 4.3 0.15549724 iYCL050C 0.528619173 0.117776276 0.704577219 APA1 -- purine metabolism -- ATP adenylyltransferase I YCR096C A2 2.5 0.986887396 iYCR096C YCR097W-A 0.988131424 0.971347271 0.498165618 0.256664006 0.57442348 A2 -- unknown -- Regulatory protein A2p (no known function)sequence is the same as the last 119 residues of Alpha2p YKL163W PIR3 2.5 0.475975459 iYKL164C-0 iYKL164C-1 0.276315288 0.282097354 0.695610535 0.355140187 0.379728651 PIR3 -- unknown -- similarity to members of Pir1p/Hsp150p/Pir3p family YCR039C ALPHA2 2.4 0.99141287 iYCR039C 0.984495399 0.532549146 0.232972957 "ALPHA2 -- transcription -- Homeodomain regulatory protein Alpha2p, interacts with Mcm1p to repress a-specific genes and with A1p to repress haploid-specific genes" YBR101C YBR101C 2.2 0.871586633 iYBR101C 0.406575559 0.994569242 0.750199521 YBR101C -- unknown -- resistance to H2O2 YER004W YER004W 2.2 0.389977956 iYER003C 0.322021823 0.569533626 0.321243726 YER004W -- unknown -- unknown function YOL052C-A DDR2 2 0.79971805 iYOL053C-A 0.760012048 0.487592652 0.037686168 "DDR2 -- unknown -- Stress protein induced by DNA damage, heat shock, osmotic shock and oxidative stress" YNL036W NCE103 1.9 0.377286709 iYNL037C 0.850580047 "NCE103 -- secretion, non-classical -- protection against oxidative damage" YDR542C 1.7 YGR143W SKN1 1.5 0.894413994 iYGR142W iYGRWdelta22 0.569725457 0.879274269 0.891122292 0.198802873 0.103070175 "SKN1 -- cell wall biogenesis -- Glucan synthase subunit involved in synthesis of beta-1,6-glucan" YDL020C RPN4 1.3 0.81603625 iYDL020C 0.808369487 0.793375898 0.803999013 "RPN4 -- protein degradation, ubiquitin-mediated -- Subunit of regulatory particle of proteasome, also binds DNA to act as a positive regulator of expression of many proteosome subunit genes" YGR146C YGR146C 1.2 0.216840902 iYGR146C 0.387266886 0.281533892 0.681254368 YGR146C -- unknown -- unknown function YIL143C SSL2 1.2 0.541612893 iYIL143C 0.54870046 0.831811075 0.328708559 SSL2 -- transcription; DNA repair -- DNA helicase component of RNA polymerase II transcription initiation factor TFIIH YCR005C CIT2 1.1 0.656094056 iYCR005C 0.347548254 0.728424179 0.309055752 "CIT2 -- glyoxylate cycle -- Citrate synthase, peroxisomal (nonmitochondrial), converts acetyl-CoA and oxaloacetate into citrate plus CoA" YDR171W HSP42 1 0.344362018 iYDR170W-A-0 iYDR170W-A-1 0.064536694 0.41644882 0.938492734 0.328393183 0.569368353 "HSP42 -- cytoskeleton assembly -- Heat shock similarity to Hsp26p, involved in restoration of cytoskeleton during mild stress" YGL178W MPT5 1 0.220664542 iYGL177W-0 iYGL177W-1 0.051740084 0.183898513 0.424261772 0.200079808 0.251542829 "MPT5 -- unknown -- high temperature growth, recovery from alpha-factor arrest, and normal lifespan of yeast cells" YOR220W YOR220W 1 0.364524287 iYOR219C 0.500093081 0.696089385 0.278293135 YOR220W -- unknown -- unknown function YCL057W PRD1 0.9 0.430558171 iYCL058C 0.423799709 0.74017219 0.340143655 "PRD1 -- protein degradation -- Proteinase yscD (saccharolysin), contains the zinc metalloendoprotease motif HEXXH" YGL016W KAP122 0.9 0.533397148 iYGL017W 0.564921544 0.961036921 0.627215598 "KAP122 -- drug resistance -- Nuclear transport factor, member of karyopherin-beta family" YHR086W NAM8 0.9 0.525899461 iYHR085W 0.115557747 0.886695906 0.145067062 "NAM8 -- RNA splicing, mitochondrial -- U1 snRNA-associated protein, essential for meiotic recombination, suppressor of mitochondrial splicing defects, has 3 RNA recognition (RRM) domains" YHR214W-A YHR214W-A 0.9 0.025893975 iYHR214W 0.01919523 0.051464064 0.020789658 YHR214W-A -- unknown -- unknown function YJR013W YJR013W 0.9 0.45503348 iYJR012C 0.148939615 0.655803824 0.268164239 YJR013W -- unknown -- weak similarity to human angiotensin II type 1b receptor YKR029C YKR029C 0.9 0.216316866 iYKR029C 0.20933946 0.334403028 0.48262402 "YKR029C -- unknown -- similarity to E(z) Enhancer of zeste in the C-terminal domain, contains a PHD finger" YLL040C VPS13 0.9 0.42455262 iYLL040C 0.564270682 0.463583629 0.298006636 VPS13 -- vacuolar protein targeting -- vacuolar sorting YMR113W FOL3 0.9 0.544106566 iYMR112C 0.298669045 0.829358685 0.492635563 FOL3 -- unknown -- Dihydrofolate synthetase YOR065W CYT1 0.9 0.448557042 iYOR064C 0.237199197 0.741466712 0.122703835 "CYT1 -- oxidative phosphorylation -- Cytochrome c1, member of cytochrome bc1 complexhas an intermembrane space (IMS) sorting signal that does not require Imp1p for cleavage" YBL035C POL12 0.8 0.545906465 iYBL035C 0.737869097 0.698436996 0.545772187 "POL12 -- DNA replication -- DNA polymerase alpha 86 kDa subunit, B subunit of polymerase alpha-primase complex" YBL078C AUT7 0.8 0.52270966 iYBL078C 0.542594001 0.714608373 0.411864176 "AUT7 -- autophagy -- mediates attachment of autophagosomes to microtubulesin combination with Aut2p, also required for sporulation" YBR043C YBR043C 0.8 0.740551066 iYBR043C 0.7137033 0.581443423 0.85027933 YBR043C -- unknown -- Member of multidrug-resistance 12-spanner family of major facilitator superfamily (MFS-MDR) YBR140C IRA1 0.8 0.598481308 iYBR140C 0.74956609 0.484531099 0.857781027 "IRA1 -- signaling, Ras pathway -- GTPase-activating protein for Ras1p and Ras2p" YDL073W YDL073W 0.8 0.42136884 iYDL074C 0.417592839 0.390417036 0.772719948 YDL073W -- unknown -- unknown function YDR291W YDR291W 0.8 0.493841562 0.821694319 YDR291W -- unknown -- similarity to Sgs1p and other DNA helicases YDR333C YDR333C 0.8 0.480789242 iYDR333C 0.494748389 0.821005082 0.44820431 YDR333C -- unknown -- unknown function YER027C GAL83 0.8 0.281443973 iYER027C 0.658339913 0.608607245 0.48447205 "GAL83 -- glucose repression -- glucose repression, interacts with Snf1p and Snf4p" YER071C YER071C 0.8 0.558437328 iYER071C 0.563065542 0.589993502 0.768437297 YER071C -- unknown -- unknown function YER103W SSA4 0.8 0.462650802 iYER102W 0.367249474 0.842330003 "SSA4 -- ER and mitochondrial translocation -- chaperone of HSP70 family, cytoplasmic heat-induced form that is not expressed under optimal conditions" YHR080C YHR080C 0.8 0.57494629 iYHR080C 0.513032216 0.691024815 0.187056438 "YHR080C -- unknown -- unknown function, has similarity to Yfl042p" YIL155C GUT2 0.8 0.602699072 iYIL155C 0.113890238 0.508934373 0.095760234 GUT2 -- glycerol metabolism -- Mitochondrial FAD-dependent glycerol-3-phosphate dehydrogenase YLR131C ACE2 0.8 0.482434559 iYLR131C 0.373605304 0.501774248 0.521277963 "ACE2 -- transcription -- Metallothionein expression activator with similarity to Swi5p, has three tandem C2H2-type zinc fingers" YLR327C YLR327C 0.8 0.476017054 iYLR327C tS(GCU)L 0.479010143 0.535666745 0.385173832 0.396401118 0.013239116 YLR327C -- unknown -- strong similarity to Stf2p YAR018C KIN3 0.7 0.630199711 iYAR018C 0.41530057 0.380523067 0.697588126 KIN3 -- unknown -- Serine/threonine protein kinase YCL049C YCL049C 0.7 0.666317323 iYCL049C 0.676930362 0.699604743 0.726681311 YCL049C -- unknown -- unknown function YCR095C YCR095C 0.7 0.743849128 iYCR095C-0 iYCR095C-1 0.376320548 0.845959217 0.780373832 0.523042217 0.410493827 YCR095C -- unknown -- unknown function YDR141C DOP1 0.7 0.283488051 iYDR141C 0.3290574 0.545681598 0.26799441 DOP1 -- unknown -- similarity to Aspergillus nidulans dopA YDR538W PAD1 0.7 0.548564679 0.943096568 PAD1 -- phenylacrylic acid resistance -- Phenylacrylic acid decarboxylase YGL010W YGL010W 0.7 0.670417908 iYGL011C 0.499335276 0.787644639 0.651305189 YGL010W -- unknown -- unknown function YGR197C SNG1 0.7 0.427435154 iYGR197C 0.442105925 0.657094458 0.584803854 "SNG1 -- nitrosoguanidine resistance -- Probable transport protein, confers resistance to MNNG and nitrosoguanidine" YHR043C DOG2 0.7 0.390900147 iYHR043C 0.384719543 0.753730741 0.585867549 "DOG2 -- 2-deoxyglucose resistance -- 2-Deoxyglucose-6-phosphate phosphatase, converts 2-deoxy-D-glucose 6-phosphate to 2-deoxy-D-glucose and orthophosphate" YIL107C PFK26 0.7 0.244212401 iYIL107C 0.348170533 0.637020793 0.373843285 "PFK26 -- fructose and mannose metabolism -- 6-Phosphofructose-2-kinase, isozyme 1" YKL204W EAP1 0.7 0.335149478 iYKL205W 0.64413 0.270056776 0.550119713 "EAP1 -- unknown -- unknown function, probable purine nucleotide-binding associates with translation initiation factor eIF4E" YKR054C DYN1 0.7 0.669617243 iYKR054C 0.569246994 0.514075986 0.789864326 "DYN1 -- cytoskeleton -- Cytoplasmic dynein, heavy chain, mutants have defect in spindle orientation and nuclear migration" YKR089C YKR089C 0.7 0.480363861 iYKR089C 0.678528709 0.55642408 0.661425577 YKR089C -- unknown -- unknown function YAR033W YAR033W 0.6 0.491525049 iYAR031W 0.349353148 0.748227522 0.733040702 "YAR033W -- unknown -- similarity to subtelomerically-encoded proteins such as Cos5p, Ybr302p, Cos3p, Cos1p, Cos4p, Cos8p, Cos6p, Cos9p, and Ycr007p" YCL062W YCL063W 0.6 YCL063W -- Deleted due to sequence correction -- sensitivity to certain drugshas similarity to plant aminocyclopropane-1-carboxylate synthase YDR078C YDR078C 0.6 0.81061274 iYDR078C 0.458068288 0.917072775 0.247181766 YDR078C -- unknown -- unknown function YDR534C YDR534C 0.6 0.192890015 iYDR534C-0 iYDR534C-1 0.692675319 0.300009387 0.419265757 0.672179709 0.399441341 YDR534C -- unknown -- unknown function YEL017W YEL017W 0.6 0.154409891 iYEL017C-A 0.083591889 0.175660444 0.038833387 YEL017W -- unknown -- unknown function YER066W YER066W 0.6 0.188551888 iYER065C YERCdelta10 0.356358921 0.836172699 0.555706305 0.173541734 0.557876906 "YER066W -- unknown -- similarity to Cdc4p, has one WD (WD-40) domain" YER081W SER3 0.6 0.947042956 iYER080W 0.715152987 0.975150169 0.529663458 SER3 -- serine biosynthesis -- 3-phosphoglycerate dehydrogenaseinvolved in synthesis of serine from 3-phosphoglycerate YFL043C 0.6 0.395449795 0.816276803 YGL110C YGL110C 0.6 0.383216616 iYGL110C 0.641324719 0.619988707 0.413325805 YGL110C -- unknown -- unknown function YGR071C YGR071C 0.6 0.507603971 iYGR071C 0.362776588 0.762281197 0.330806065 YGR071C -- unknown -- unknown function YGR098C ESP1 0.6 0.554264793 iYGR098C 0.489558038 0.259870677 0.63877232 "ESP1 -- cytoskeleton -- Separin Mcd1p cleavage and sister chromatid separation, also involved in regulation of spindle pole body duplication" YHR182W YHR182W 0.6 0.31096888 iYHR181W 0.149157317 0.472067039 0.122206986 YHR182W -- unknown -- unknown function YIL067C YIL067C 0.6 0.623080085 iYIL067C 0.378716645 0.86513618 0.369867522 YIL067C -- unknown -- unknown function YIL156W UBP7 0.6 0.282575335 iYIL157C 0.142493844 0.45758789 0.237721678 "UBP7 -- protein degradation, ubiquitin-mediated -- Putative ubiquitin-specific protease (ubiquitin C-terminal hydrolase)" YJR030C YJR030C 0.6 0.248754495 iYJR030C 0.546269036 0.7437696 0.489673332 YJR030C -- unknown -- unknown function YKL032C IXR1 0.6 0.30774729 iYKL032C 0.899806076 0.273902634 0.165685246 "IXR1 -- transcription, oxygen-dependent -- Intrastrand crosslink recognition protein and transcription factor that confers oxygen (O2) regulation on COX5B, has 2 HMG-box DNA-binding domains" YKR027W YKR027W 0.6 0.507210379 iYKR026C YKRCdelta9 0.681586709 0.478148878 0.77931375 0.861612131 0.361374193 YKR027W -- unknown -- unknown function YML016C PPZ1 0.6 0.325649815 iYML016C 0.459519681 0.229775828 0.271784745 "PPZ1 -- stress response -- Protein serine/threonine phosphatase required for normal osmoregulation, member of PPP family of protein phosphatases and related to PP1 phosphatases" YMR126C YMR126C 0.6 iYMR126C 0.189463737 0.207683561 YMR126C -- unknown -- unknown function YOL032W YOL032W 0.6 0.076007771 iYOL033W 0.457315136 0.395787048 YOL032W -- unknown -- unknown function YAR068W YAR068W 0.4 0.189544938 iYAR066W 0.081321333 0.199726072 0.199248777 YAR068W -- unknown -- similarity to ICWP protein YBL105C PKC1 0.4 0.579323679 iYBL105C 0.570403287 0.637345679 0.568137451 PKC1 -- cell wall biogenesis -- kinase Cregulates MAP kinase cascade involved in regulating cell wall metabolism YBR037C SCO1 0.4 0.391533107 iYBR037C 0.179275612 0.916759777 0.290854451 SCO1 -- respiration -- possible role in copper transport or insertion of copper into cytochrome oxidaseparalog of Sco2p YBR169C SSE2 0.4 0.395049784 iYBR169C 0.427317293 0.491300878 0.333145343 "SSE2 -- heat shock response -- Heat shock HSP70 family, present at low abundance at 23 deg but greatly induced after shift to 37 deg" YDL030W PRP9 0.4 0.423483722 iYDL031W 0.552429027 0.54009434 0.584818309 "PRP9 -- mRNA splicing -- Pre-mRNA splicing factor (snRNA-associated protein), required for addition of U2 snRNA to prespliceosomes, has two C2H2-type zinc fingers" YDR323C PEP7 0.4 0.555382435 iYDR323C 0.611391736 0.925276153 0.757838917 "PEP7 -- vacuolar protein targeting -- Vacuolar segregation vacuole inheritance and vacuole protein sorting, has a single C2H2-type zinc finger" YEL048C YEL048C 0.4 0.606603728 iYEL048C 0.819499591 0.664657582 0.730502739 YEL048C -- unknown -- unknown function YGL134W PCL10 0.4 0.886097183 iYGL135W 0.897435288 0.866661289 0.460494812 "PCL10 -- cell cycle -- Cyclin that associates with Pho85p, involved in glycogen accumulation" YGR046W YGR046W 0.4 0.615024049 iYGR045C 0.332604215 0.885984708 0.593780213 YGR046W -- unknown -- Essential unknown functionhas similarity to phage 1C ANTP-139 protein PIR YGR089W YGR089W 0.4 0.183719628 iYGR088W 0.713232898 0.423408889 0.857699805 YGR089W -- unknown -- similarity to human desmoplakin I PIR YGR161C YGR161C 0.4 0.554398179 iYGR161C-0 iYGR161C-1 0.373554233 0.319779914 0.064465409 0.521352752 0.695087521 "YGR161C -- unknown -- unknown function, has phosphopantetheine attachment site" YGR166W KRE11 0.4 0.240807798 iYGR165W 0.445897184 0.714884696 0.736464558 KRE11 -- cell wall biogenesis -- High molecular weight subunit of Transport Protein Particle complex that is involved in vesicular transport from the ER to the Golgi YGR168C YGR168C 0.4 0.713703982 iYGR168C 0.521833465 0.890457369 0.514882633 YGR168C -- unknown -- similarity to human vasoactive intestinal peptide receptor PIR YGR243W YGR243W 0.4 0.546394767 iYGR242W 0.231647658 0.711302188 0.166895217 YGR243W -- unknown -- unknown function YGR247W YGR247W 0.4 0.242033997 iYGR246C 0.49060464 0.473707198 0.633200319 YGR247W -- unknown -- Cyclic nucleotide phosphodiesterase YGR250C YGR250C 0.4 0.467560723 iYGR250C-0 iYGR250C-1 0.290386629 0.47485632 0.738404453 0.426554812 0.745011971 "YGR250C -- unknown -- three RNA Recognition (RRM) domains, has similarity to human 64K polyadenylation factor" YHR209W YHR209W 0.4 0.516057468 iYHR208W 0.230039898 0.801320681 0.356708347 YHR209W -- unknown -- Putative SAM-dependent methyltransferasehas similarity to Yer175p YIL015C-A YIL015C-A 0.4 0.327981112 iYIL015C-A itT(AGU)I2 0.682531813 0.756333031 0.214884696 0.737589785 0.590103751 YIL015C-A -- unknown -- unknown function YIL117C YIL117C 0.4 0.562832294 iYIL117C 0.359909238 0.930031447 0.423702868 YIL117C -- unknown -- unknown function YIR007W YIR007W 0.4 0.231306824 iYIR006C itE(UUC)I 0.506956588 0.792105475 0.783746331 0.493458405 0.426232206 YIR007W -- unknown -- similarity to endoglucanase YJR008W YJR008W 0.4 0.485449378 iYJR007W 0.630857621 0.747881182 0.504309657 YJR008W -- unknown -- unknown function YJR033C RAV1 0.4 0.153042613 iYJR033C 0.573744102 0.38525467 0.329434541 RAV1 -- unknown -- regulation of (H+)-ATPase in vacuolar membrane YJR052W RAD7 0.4 0.21610446 iYJR051W YJLWdelta15 0.554970411 0.590322319 0.323623304 0.465419234 0.73264166 "RAD7 -- DNA repair, nucleotide excision -- Nucleotide excision repair G2 repair of inactive genes" YJR102C YJR102C 0.4 0.768161716 iYJR102C 0.550273905 0.966564615 0.703182268 "YJR102C -- unknown -- normal mating efficiency, pseudohyphal growth, and resistance to NaCL, KCl, and H2O2" YKL005C YKL005C 0.4 0.472587449 iYKL005C 0.243838337 0.740976474 0.361101724 "YKL005C -- unknown -- similarity to Drosophila transcription factor TFIIS, contains a PHD finger" YKL047W YKL047W 0.4 0.382648972 iYKL048C 0.486760095 0.852725367 0.419614282 "YKL047W -- unknown -- unknown function, has 2 predicted transmembrane segments" YKL139W CTK1 0.4 0.361602857 iYKL140W 0.612461931 0.64896874 0.880441845 "CTK1 -- transcription -- C-terminal domain (CTD) kinase alpha subunit, cyclin-dependent protein kinase that phosphorylates C-terminal domain of RNA polymerase II large subunit Rpo21p" YKR046C YKR046C 0.4 0.129431626 iYKR046C 0.184725501 0.351654149 0.250873515 YKR046C -- unknown -- Protein possibly involved in respiration YLR137W YLR137W 0.4 0.364192303 iYLR136C 0.181839503 0.664311241 0.158034369 YLR137W -- unknown -- unknown function YLR212C TUB4 0.4 0.236755033 iYLR212C 0.568501692 0.493345164 0.607315501 "TUB4 -- cytoskeleton -- Gamma tubulin, required for microtubule organization and nuclear division" YLR228C ECM22 0.4 0.151438013 iYLR228C-0 iYLR228C-1 0.060628137 0.490414004 0.427603452 0.13272443 0.763762034 "ECM22 -- unknown -- similarity to transcription factors, has Zn[2]-Cys[6] fungal-type binuclear cluster domain in the N-terminal region" YLR253W YLR253W 0.4 0.455744031 iYLR252W 0.601680941 0.603032721 0.790793152 YLR253W -- unknown -- weak similarity to Abc1p YLR272C LOC7 0.4 0.41924592 iYLR272C itV(AAC)L 0.145484261 0.705953789 0.859571383 0.118012422 0.771579034 "LOC7 -- mitosis, sister chromatid cohesion -- Subunit of condensin protein complex required for proper chromosome condensation and segregation" YML120C NDI1 0.4 0.446417493 iYML120C 0.306104818 0.773318689 0.756767876 NDI1 -- oxidative phosphorylation -- NADH-ubiquinone oxidoreductase YML128C YML128C 0.4 0.456866564 iYML128C 0.421654812 0.801453194 0.44837783 YML128C -- unknown -- unknown function YMR029C YMR029C 0.4 0.325095901 iYMR029C 0.213410108 0.665185551 0.451503886 "YMR029C -- unknown -- unknown function, has potential coiled-coil region" YMR103C YMR103C 0.4 0.790733658 iYMR103C 0.217016237 0.897233202 0.318723816 "YMR103C -- unknown -- unknown function, questionable ORF" YMR109W MYO5 0.4 0.304711806 iYMR108W 0.492077752 0.211799556 0.453874599 "MYO5 -- cytoskeleton -- Myosin type I, may play a role in cell growth or polarity that is partially redundant with Myo3p, has an SH3 domain" YMR176W ECM5 0.4 0.3763955 iYMR175W 0.390504815 0.513352055 0.781429537 ECM5 -- cell wall biogenesis -- cell wall structure or biosynthesis YMR201C RAD14 0.4 0.398663692 iYMR201C 0.234393932 0.05570641 0.334468903 "RAD14 -- DNA repair, nucleotide excision -- Zinc-binding nucleotide excision repairosome, homolog of human XPA xeroderma pigmentosum gene product" YMR216C SKY1 0.4 0.713083959 iYMR216C 0.151475731 0.922665603 0.33811504 SKY1 -- unknown -- Serine/threonine protein kinase involved in phosphorylation of Npl3p YMR227C TAF67 0.4 0.188960878 iYMR227C 0.373876588 0.105220754 0.42974334 "TAF67 -- transcription -- Component of TAF(II) complex (TBP-associated factor), required for activated transcription by RNA polymerase II" YMR250W GAD1 0.4 0.700637226 iYMR247C itA(AGC)M2 0.669269026 0.632236905 0.707196231 0.314534322 0.468903767 GAD1 -- unknown -- Glutamate decarboxylase YOL113W SKM1 0.4 0.491396304 iYOL114C 0.200373468 0.41594668 0.349978741 SKM1 -- unknown -- Serine/threonine protein kinase with similarity to Ste20p and Cla4p YOR181W LAS17 0.4 0.096689982 iYOR180C 0.620153638 0.08665269 0.678793256 LAS17 -- cytoskeleton -- Component of cortical actin cytoskeleton YPL151C PRP46 0.4 0.221299374 iYPL151C 0.41996835 0.553808526 0.404469274 "PRP46 -- mRNA splicing -- Putative spliceosomal similarity to S. pombe prp5p, has four WD (WD-40) repeats" YPR202W YPR202W 0.4 0.98274031 iYPR201W-0 iYPR201W-1 0.295404814 0.992105513 0.702304222 0.233524839 0.081790123 YPR202W -- unknown -- similarity to other subtelomerically-encoded proteins YBL063W KIP1 0.3 0.321198803 iYBL064C 0.434917698 0.329209896 0.542147294 "KIP1 -- mitosis, spindle assembly -- Kinesin-related establishment and maintenance of mitotic spindle" YBR057C MUM2 0.3 0.362920922 iYBR057C 0.868421083 0.578266946 0.584470435 MUM2 -- meiosis -- premeiotic DNA synthesis and sporulation YBR072W HSP26 0.3 0.760378436 iYBR071W 0.459148017 0.703193647 0.446398322 "HSP26 -- diauxic shift -- Heat shock 26kD, expressed during entry to stationary phase and induced by osmostress" YBR296C PHO89 0.3 0.393777487 iYBR296C-0 iYBR296C-1 0.84068749 0.438113363 0.426157486 0.501492297 0.29688747 PHO89 -- phosphate metabolism -- High-affinity Na+-dependent phosphate transporter YBR298C MAL31 0.3 0.368486646 iYBR298C 0.759861897 0.558602888 0.834206848 "MAL31 -- transport -- High affinity maltose/H+ symporter (maltose permease), member of hexose transporter family of major facilitator superfamily (MFS)" YCR015C YCR015C 0.3 0.311945593 iYCR015C SNR33 0.71492119 0.332006864 0.337317718 0.505708919 0.154269753 YCR015C -- unknown -- unknown function YCR021C HSP30 0.3 0.258961029 iYCR021C 0.588674198 0.520866903 0.627167863 "HSP30 -- diauxic shift -- Heat shock protein located in plasma membrane, expressed during entry to stationary phase" YCR030C YCR030C 0.3 0.229422007 iYCR030C SNR65 0.791301552 0.884277009 0.258211041 0.947991481 0.692614181 YCR030C -- unknown -- unknown function YDL089W YDL089W 0.3 0.623265345 iYDL090C 0.202310112 0.658978452 0.350104822 YDL089W -- unknown -- unknown function YDL113C YDL113C 0.3 0.55293341 iYDL113C 0.371309075 0.47614446 0.32555905 YDL113C -- unknown -- unknown function YDL203C YDL203C 0.3 0.190048979 iYDL203C 0.529811989 0.679503706 0.670073375 YDL203C -- unknown -- unknown function YDL205C HEM3 0.3 0.27135182 iYDL205C 0.271826407 0.576376696 0.261355695 "HEM3 -- heme biosynthesis -- Porphobilinogen deaminase (pre-uroporphyrinogen synthase), catalyzes the third step in porphyrin biosynthesis pathway" YDR109C YDR109C 0.3 0.810435886 iYDR109C 0.804485891 0.690247641 0.070055905 YDR109C -- unknown -- similarity to FGGY kinase family YDR181C SAS4 0.3 0.192732358 iYDR181C 0.574142742 0.847833683 0.348183089 "SAS4 -- silencing -- silencing at telomeres and the silent mating-type loci, HML and HMR" YDR273W YDR273W 0.3 0.414042817 iYDR272W 0.405138192 0.656920078 0.434748428 YDR273W -- unknown -- unknown function YEL029C YEL029C 0.3 0.53851628 iYEL029C 0.500213555 0.591675405 0.553903346 YEL029C -- unknown -- similarity to putative Salmonella phosphotransferase system transcriptional regulator ptsJ YER041W YER041W 0.3 0.328385038 iYER040W 0.214232007 0.702376728 0.36465022 YER041W -- unknown -- similarity to DNA repair protein Rad2p YER060W-A FCY22 0.3 0.517474086 iYER060W 0.28857718 0.444852354 0.130255904 "FCY22 -- transport -- Purine/cytosine permease with similarity to Fcy2p, member of purine/cytosine subfamily of nucleobase" YER150W SPI1 0.3 0.120311162 iYER149C 0.288297179 0.315479552 0.332742507 "SPI1 -- unknown -- induced in stationary phase, has similarity to Sed1p" YFR019W FAB1 0.3 0.538502607 iYFR018C 0.333740209 0.388546038 0.110136452 FAB1 -- mitosis -- Phosphatidylinositol-3-phosphate 5-kinase involved in orientation or separation of mitotic chromosomes YFR020W YFR020W 0.3 0.402129458 iYFR019W itS(GCU)F 0.255134566 0.565419797 0.620695257 0.095633258 0.136158556 YFR020W -- unknown -- unknown function YGL003C CDH1 0.3 0.599636198 iYGL003C 0.35550903 0.904689011 0.372428813 "CDH1 -- cell cycle -- Clb2p cyclin proteolysis, has WD (WD-40) repeats" YGL025C PGD1 0.3 0.294075086 0.362596087 "PGD1 -- transcription -- Component of RNA polymerase II holoenzyme and mediator subcomplex, involved in both positive and negative regulation of transcription" YGL102C YGL102C 0.3 0.939160112 iYGL102C 0.706060111 0.630636444 0.236397432 YGL102C -- unknown -- unknown function YGL136C YGL136C 0.3 0.96921429 iYGL136C 0.991967285 0.654351859 0.908959072 "YGL136C -- unknown -- similarity to E. coli ftsJ protein, putative SAM-dependent methyltransferase" YGR013W SNU71 0.3 0.210213188 iYGR012W 0.309679576 0.311327304 0.303335482 SNU71 -- mRNA splicing -- U1 snRNA-associated protein YGR050C YGR050C 0.3 0.828274503 iYGR050C 0.80709268 0.825620756 0.489146049 YGR050C -- unknown -- unknown function YGR122W YGR122W 0.3 0.72555603 iYGR121C 0.378607501 0.961771748 0.744639376 YGR122W -- unknown -- unknown function YGR142W BTN2 0.3 0.583989608 iYGR141W 0.329870379 0.338382211 0.364605171 BTN2 -- unknown -- elevated expression in yhc3 mutants YGR196C YGR196C 0.3 0.237830537 iYGR196C 0.596561287 0.494846232 0.537468742 YGR196C -- unknown -- unknown function YGR271W YGR271W 0.3 0.375847116 iYGR270W 0.44826934 0.689816307 0.514683092 YGR271W -- unknown -- strong similarity to U5 snRNP-associated Brr2p YHR061C GIC1 0.3 0.602112703 iYHR061C 0.765143471 0.820601758 0.316344232 "GIC1 -- bud emergence -- Putative effector of Cdc42p, important for bud emergence" YHR166C CDC23 0.3 0.310375139 iYHR166C 0.255674108 0.821135539 0.515227199 CDC23 -- mitosis -- Component of anaphase-promoting complex (APC)required for Clb2p degradation and for the metaphase-anaphase transition YIL056W YIL056W 0.3 0.702082155 iYIL057C itS(UGA)I 0.79949363 0.277043817 0.878504673 0.190241093 0.146036387 YIL056W -- unknown -- unknown function YJL018W YJL018W 0.3 0.707152716 0.836871508 "YJL018W -- unknown -- unknown function, overlaps with YJL018W" YJL084C YJL084C 0.3 0.253279878 iYJL084C 0.114800199 0.527932961 0.227268987 YJL084C -- unknown -- unknown function YJL139C YUR1 0.3 0.48887648 iYJL139C 0.547665545 0.606783719 0.310087214 YUR1 -- protein glycosylation -- Mannosyltransferase of KRE2 family involved in N-linked glycosylation YJL201W ECM25 0.3 0.362780834 iYJL202C 0.519412499 0.891425345 ECM25 -- cell wall biogenesis -- Protein possibly involved in cell wall structure or biosynthesis YJR039W YJR039W 0.3 0.29979089 0.707431125 YJR039W -- unknown -- similarity to Paramecium tetraurelia NADH dehydrogenase chain 4 YJR110W YJR110W 0.3 0.329860062 iYJR109C 0.55621808 0.364765901 0.606114383 "YJR110W -- unknown -- Protein tyrosine phosphatase (PTPase) of unknown function, has similarity to human myotubularin MTM1" YKL079W SMY1 0.3 0.480691187 iYKL080W 0.690867308 0.743083004 0.337261145 "SMY1 -- cytoskeleton -- kinesin family, can interact with or substitute for Myo2p" YKL091C YKL091C 0.3 0.178808306 iYKL091C 0.413268101 0.871754514 0.507529028 YKL091C -- unknown -- similarity to Sec14p YKL134C 1-Oct 0.3 0.204075948 iYKL134C 0.463475454 0.739981897 0.704434698 OCT1 -- mitochondrial protein targeting -- Mitochondrial intermediate peptidase YKL169C YKL169C 0.3 0.732283423 iYKL169C 0.233215949 0.845391557 0.255559136 YKL169C -- unknown -- unknown functionquestionable ORF YKR011C YKR011C 0.3 0.701139348 iYKR011C 0.549361386 0.84127376 0.731045491 YKR011C -- unknown -- unknown function YKR017C YKR017C 0.3 0.257369321 iYKR017C 0.428651821 0.60763777 0.540181691 "YKR017C -- unknown -- unknown function, has a TRIAD composite zinc finger domain" YKR045C YKR045C 0.3 0.194308698 iYKR045C 0.306022285 0.399545772 0.219601677 YKR045C -- unknown -- unknown function YKR077W YKR077W 0.3 0.066921888 iYKR076W 0.339613287 0.175429935 0.315226558 YKR077W -- unknown -- unknown function YLR067C PET309 0.3 0.482630582 iYLR067C 0.333615938 0.816759777 0.066507205 PET309 -- RNA processing -- stability and translation of COX1 mRNA YLR145W YLR145W 0.3 0.163494381 iYLR144C 0.415404529 0.231581615 0.207782791 YLR145W -- unknown -- unknown function YLR187W YLR187W 0.3 0.107629596 iYLR186W 0.512706016 0.268081761 0.660989056 YLR187W -- unknown -- unknown function YLR247C YLR247C 0.3 0.182103408 iYLR247C 0.104758594 0.359243015 0.229046975 YLR247C -- unknown -- similarity to Rad16p YLR254C YLR254C 0.3 0.26445348 iYLR254C 0.273924194 0.103842673 0.011530398 YLR254C -- unknown -- unknown function YLR455W YLR455W 0.3 0.222436639 iYLR454W itI(AAU)L2 0.731796878 0.838589176 0.221020615 0.532436561 0.833344243 YLR455W -- unknown -- unknown function YMR037C MSN2 0.3 0.238427389 iYMR037C 0.3216972 0.248427673 0.237246681 "MSN2 -- stress response -- Zinc-finger transcriptional activator for genes involved in the multistress response and genes regulated through Snf1p, has two tandem C2H2-type zinc fingers" YMR040W YMR040W 0.3 0.297786462 iYMR039C 0.088594506 0.419814038 0.038695505 YMR040W -- unknown -- similarity to Ykl065p YMR086W YMR086W 0.3 0.563946 iYMR085W 0.371849258 0.53045809 0.196592931 YMR086W -- unknown -- unknown function YMR105C PGM2 0.3 0.524351094 iYMR105C 0.151837371 0.551505722 0.115856167 "PGM2 -- glycolysis -- Phosphoglucomutasemajor isozyme, interconverts Glc-1-P and Glc-6-P" YMR111C YMR111C 0.3 0.180563449 iYMR111C 0.345860923 0.542560104 0.297482258 YMR111C -- unknown -- similarity to Msn1p YMR162C YMR162C 0.3 0.750720909 iYMR162C 0.370672623 0.522626442 0.415404447 YMR162C -- unknown -- Member of Drs2p family of P-type ATPase superfamily YMR192W YMR192W 0.3 0.39275982 iYMR191W 0.170524718 0.402436073 0.106918239 YMR192W -- unknown -- similarity to mouse Tbc1 protein YNL095C YNL095C 0.3 0.918926249 iYNL095C 0.160741191 0.77565842 0.316759777 YNL095C -- unknown -- similarity to Ecm3p YOL138C YOL138C 0.3 0.163609321 iYOL138C 0.435265297 0.411712511 0.836988304 "YOL138C -- unknown -- unknown function, has WD (WD-40) repeats" YOR035C SHE4 0.3 0.743564837 iYOR035C 0.085732813 0.028359652 SHE4 -- asymmetric HO expression -- mother cell-specific expression of HO and receptor mediated as well as membrane lipid endocytosis YPL247C YPL247C 0.3 0.233612086 iYPL247C 0.1944467 0.419549266 0.241348713 "YPL247C -- unknown -- unknown function, has WD (WD-40) repeats" YPR018W RLF2 0.3 0.056592011 iYPR017C 0.095229418 0.013823747 0.06505848 RLF2 -- chromatin structure -- Chromatin assembly complex subunit 1involved in nucleosome assembly linked with DNA replication YPR154W YPR154W 0.3 0.434120293 iYPR153W 0.43743265 0.146049481 0.458820647 "YPR154W -- unknown -- one SH3 domain, has similarity to myosin ID and IC heavy chains, human growth factor receptor-bound grb2 protein, C. elegans sex muscle abnormal protein 5" YAL061W YAL061W 0.2 0.620088399 iYAL062W 0.545176995 0.580653021 0.646043398 YAL061W -- unknown -- similarity to alcohol/sorbitol dehydrogenasemember of zinc-containing alcohol dehydrogenase family YAR023C YAR023C 0.2 0.619581337 iYAR023C itL(CAA)A 0.228411829 0.70893782 0.872623268 0.721303541 0.789725974 "YAR023C -- unknown -- strong similarity to subtelomerically-encoded proteins such as Cos5p, Ybr302p, Cos3p, Cos1p, Cos4p, Cos8p, Cos6p, Cos9p" YBL048W YBL048W 0.2 0.457129554 0.35082651 YBL048W -- unknown -- unknown function YBL075C SSA3 0.2 0.68188441 iYBL075C 0.250774884 0.894537544 0.180110742 "SSA3 -- ER and mitochondrial translocation -- Chaperone of HSP70 family, heat-induced cytoplasmic form not expressed under optimal conditions" YBL080C PET112 0.2 0.505730214 iYBL080C 0.375361259 0.682282522 0.502643533 PET112 -- protein synthesis -- may have a general role in mitochondrial translation YBL103C RTG3 0.2 0.287348618 iYBL103C 0.455717456 0.686193136 0.811260224 RTG3 -- glyoxylate cycle -- Basic helix-loop-helix (bHLH)-leucine zipper transcription factor involved in controlling metabolic interactions between mitochondria and peroxisomes YBR020W GAL1 0.2 0.319568027 iYBR019C 0.431727605 0.796045961 0.778898121 "GAL1 -- galactose metabolism -- Galactokinase, first step in galactose metabolism" YBR099C YBR099C 0.2 0.736116841 0.822591041 YBR099C -- unknown -- unknown function YBR228W YBR228W 0.2 0.225383332 iYBR227C 0.120427687 0.303142954 0.031813404 YBR228W -- unknown -- unknown function YBR275C RIF1 0.2 0.583028222 iYBR275C 0.782709522 0.497379455 0.925153078 "RIF1 -- silencing -- telomere length regulation and transcriptional silencing, interacts with Rap1p" YBR300C YBR300C 0.2 0.803116751 0.835349296 YBR300C -- unknown -- unknown function YCL051W LRE1 0.2 0.12596354 iYCL052C 0.209317817 0.540861931 0.231791814 LRE1 -- laminarase resistance -- laminarinase resistance YCL068C YCL068C 0.2 0.979307188 iYCL068C 0.954911446 0.182739343 0.008853151 YCL068C -- unknown -- strong similarity to the N-terminal third of Bud5p YCR032W BPH1 0.2 0.690357823 iYCR031C SNR189 0.391235882 0.982725285 0.460604472 0.415987739 0.583870448 "BPH1 -- transport -- Probable acetic acid export pump, has WD (WD-40) repeats in the C-terminal domain" YCR063W YCR063W 0.2 0.749677329 0.825146054 "YCR063W -- unknown -- similarity to Xenopus G10, a developmentally-regulated is thought to be involved in translation during oocyte maturation" YDL027C YDL027C 0.2 0.453343902 0.224489796 YDL027C -- unknown -- unknown function YDL139C SCM3 0.2 0.395939112 iYDL139C 0.48320887 0.470459266 0.588028731 SCM3 -- unknown -- unknown function YDL154W MSH5 0.2 0.413974337 iYDL155W 0.557470988 0.785189965 0.689494038 MSH5 -- DNA repair -- Meiosis-specific reciprocal recombinationnot involved in mismatch repair YDL233W YDL233W 0.2 0.196889095 iYDL234C 0.602977709 0.164657516 0.74179215 YDL233W -- unknown -- unknown function YDR026C YDR026C 0.2 0.376196041 iYDR026C 0.412405166 0.282488629 0.373012 YDR026C -- unknown -- similarity to Reb1p YDR081C PDC2 0.2 0.390486284 iYDR081C 0.258713476 0.623457288 0.251289075 PDC2 -- glycolysis -- Pyruvate decarboxylase regulatory protein YDR118W APC4 0.2 0.225888892 iYDR117C 0.517986659 0.447850286 0.360651771 "APC4 -- cell cycle -- Component of anaphase-promoting complex (APC), required for Clb2p degradation and for the metaphase-anaphase transition" YDR217C RAD9 0.2 0.591497273 iYDR217C 0.360706088 0.472189285 0.389067252 RAD9 -- DNA repair; DNA damage checkpoint -- DNA repair checkpoint cell cycle arrest following DNA damage YDR240C SNU56 0.2 0.64072471 YDRWdelta12 0.436143921 0.929181437 0.138549444 SNU56 -- mRNA splicing -- U1 snRNA-associated protein YDR252W BTT1 0.2 0.386071974 iYDR251W 0.628380924 0.781500944 0.515346005 "BTT1 -- transcription -- Alternate beta subunit of nascent polypeptide-associated complex, localized bound to ribosomes" YDR253C MET32 0.2 0.190216493 iYDR253C 0.275739997 0.248308089 0.247725796 "MET32 -- methionine metabolism -- Zinc-finger transcriptional regulation of methionine metabolism, has two tandem C2H2-type zinc fingers" YDR396W YDR396W 0.2 0.595121832 iYDR395W 0.75862069 0.826112153 0.45612293 YDR396W -- unknown -- unknown function YDR443C SRB9 0.2 0.564305534 iYDR443C 0.499859176 0.624989917 0.673480084 SRB9 -- transcription -- Component of RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex YDR541C YDR541C 0.2 0.738784065 iYDR541C-0 iYDR541C-1 0.894468176 0.920168083 0.799951267 0.752417016 0.690489635 YDR541C -- unknown -- weak similarity to dihydroflavonol-4-reductases YDR543C YDR543C 0.2 0.999023559 iYDR543C 0.997607301 0.078850758 0.025298099 YDR543C -- unknown -- similarity to other subtelomerically-encoded proteins YEL028W YEL028W 0.2 0.771406897 iYEL029C 0.500213555 0.913609364 0.553903346 YEL028W -- unknown -- unknown function YEL033W YEL033W 0.2 0.876884983 0.615239036 YEL033W -- unknown -- invasive growth and pseudohyphal development YEL053C MAK10 0.2 0.932452271 iYEL053C 0.846048718 0.63386849 0.776818502 MAK10 -- dsRNA virus propagation -- Glucose-repressible replication of double-stranded RNA (dsRNA) virus YER018C SPC25 0.2 0.669667057 iYER018C 0.128924161 0.687985806 0.040566115 SPC25 -- cytoskeleton -- spindle pole body YER039C HVG1 0.2 0.065434999 YER039C-A 0.37221044 0.404248264 0.23852545 "HVG1 -- protein glycosylation (putative) -- Member of nucleotide sugar transporter (NST) family of membrane transporters, has strong similarity to vanadate resistance protein Gog5p" YER051W YER051W 0.2 0.279857108 iYER050C 0.770974514 0.288417804 0.784809057 YER051W -- unknown -- unknown function YER073W ALD5 0.2 0.933783859 iYER072W 0.860631437 0.83270146 0.932127883 ALD5 -- fermentation -- Mitochondrial aldehyde dehydrogenase YER116C YER116C 0.2 0.959547371 iYER116C 0.988975343 0.538864481 0.286687631 YER116C -- unknown -- unknown function YER153C PET122 0.2 0.659606551 iYER153C 0.051573364 0.776816911 0.070175439 PET122 -- protein synthesis -- Translational activator required for mitochondrial translation of COX3 mRNA YGL051W YGL051W 0.2 0.659800458 0.913913024 "YGL051W -- unknown -- strong similarity to subtelomerically-encoded proteins such as Cos5p, Ybr302p, Cos3p, Cos1p, Cos4p, Cos8p, Cos6p, Cos9p, and Ycr007p" YGL053W YGL053W 0.2 0.663522019 iYGL054C iYGLWdelta7 0.567861576 0.356137067 0.902273688 0.460763777 0.363599742 "YGL053W -- unknown -- strong similarity to subtelomerically-encoded proteins such as Cos5p, Ybr302p, Cos3p, Cos1p, Cos4p, Cos8p, Cos6p, Cos9p, and Ycr007p" YGL063W PUS2 0.2 0.837879778 iYGL064C 0.65038292 0.915123457 0.516406758 PUS2 -- tRNA processing -- Pseudouridine synthase YGL066W YGL066W 0.2 0.086674442 iYGL067W 0.43028461 0.028970471 0.378507364 YGL066W -- unknown -- similarity to Dictyostelium discoideum G-box-binding factor YGL160W YGL160W 0.2 0.345804435 iYGL161C 0.463002287 0.621739488 0.450999753 YGL160W -- unknown -- unknown function YGL176C YGL176C 0.2 iYGL177W-2 iYGL176C 0.219286622 0.116290008 0.304469274 0.099646178 YGL176C -- unknown -- weak similarity to Discopyge ommata Ca2+ channel alpha1 subunit protein B47447 YGL212W VAM7 0.2 0.166666667 iYGL213C 0.412285552 0.739605171 0.318315788 VAM7 -- vacuole biogenesis -- Subunit of vacuolar SNARE complex involved in morphogenesis of vacuolehomologous to SNAP-25 YGR056W RSC1 0.2 0.321353408 iYGR055W 0.46970892 0.763087844 0.289392463 RSC1 -- chromatin structure -- Component of abundant RSC complex involved in chromatin remodeling YGR068C YGR068C 0.2 0.445425334 0.802553871 YGR068C -- unknown -- similarity to Rod1p YGR160W YGR160W 0.2 0.878056559 0.479489226 YGR160W -- unknown -- unknown function YGR238C KEL2 0.2 0.675531838 iYGR238C 0.169812097 0.785714286 0.295766047 KEL2 -- unknown -- cell fusion and morphologycontains six Kelch repeats YHR006W STP2 0.2 0.576610896 iYHR005C-A itT(AGU)H 0.343910098 0.60212854 0.458516391 0.248340321 0.351556322 "STP2 -- tRNA splicing -- strong similarity to Stp1p, which is involved in tRNA splicing and branched-chain amino acid uptake" YHR011W YHR011W 0.2 0.664601937 iYHR010W 0.484300116 0.783757654 0.279727096 "YHR011W -- unknown -- similarity to seryl-tRNA synthetase, member of class II family of aminoacyl-tRNA synthetases" YHR118C ORC6 0.2 0.253961178 iYHR118C 0.266759969 0.290935673 0.241146849 "ORC6 -- DNA replication -- Origin recognition complex (ORC), sixth subunit, binds domain A consensus sequence" YHR212C YHR212C 0.2 0.440310798 iYHR212C 0.399400827 0.806155334 0.5414301 YHR212C -- unknown -- identical to Yar060p/Raa19p YIL153W RRD1 0.2 0.669043193 iYIL154C 0.197914728 0.773065225 0.225890985 RRD1 -- drug resistance -- Phosphotyrosyl phosphatase activator involved in sensitivity to rapamycin and resistance to vanadate YJL146W IDS2 0.2 0.626540515 iYJL147C 0.893216281 "IDS2 -- signaling, meiosis pathway -- affects the function of Ime2p" YJL147C YJL147C 0.2 0.786904189 iYJL147C 0.88150359 YJL147C -- unknown -- unknown function YJL202C YJL202C 0.2 0.168756761 iYJL202C 0.519412499 0.271511441 YJL202C -- unknown -- unknown function YJR010W MET3 0.2 0.623455866 iYJR009C-0 iYJR009C-1 0.440022378 0.374192569 0.968901063 0.541841521 0.866065627 MET3 -- methionine biosynthesis -- ATP-sulfurylase YJR098C YJR098C 0.2 0.697176072 iYJR098C 0.245683753 0.830690938 0.306145251 YJR098C -- unknown -- unknown function YJR119C YJR119C 0.2 0.661792343 iYJR119C 0.433232257 0.909976057 0.483080889 YJR119C -- unknown -- similarity to human retinoblastoma binding protein 2 YKL017C HCS1 0.2 0.425051323 iYKL017C 0.608181003 0.591541183 0.113569419 HCS1 -- DNA replication -- DNA helicase A and Dom34p-interacting protein YKL023W YKL023W 0.2 0.063373165 iYKL024C 0.386514489 0.06717024 0.207138253 YKL023W -- unknown -- unknown function YKL048C ELM1 0.2 0.234153783 iYKL048C 0.486760095 0.595984531 0.419614282 ELM1 -- pseudohyphal growth -- Serine/threonine protein kinase regulating pseudohyphal growth YKL115C YKL115C 0.2 0.642905164 iYKL115C 0.388958026 0.724701901 0.123267996 YKL115C -- unknown -- unknown functionquestionable ORF YKL129C MYO3 0.2 0.193449976 iYKL129C 0.29813254 0.497539727 0.519803178 "MYO3 -- cytoskeleton -- Myosin type I, may play a role in cell growth or polarity that is partially redundant with Myo5p, has an SH3 domain" YKL159C RCN1 0.2 0.67886825 iYKL159C 0.258157263 0.545762166 0.238731656 RCN1 -- signaling -- inhibits calcineurin YKL187C YKL187C 0.2 0.453232034 iYKL187C 0.192543156 0.796079697 0.282761373 YKL187C -- unknown -- similarity to 4-mycarosyl isovaleryl-CoA transferase YKR020W YKR020W 0.2 0.031387099 iYKR019C 0.126674289 0.081625936 0.329347077 YKR020W -- unknown -- unknown function YLL032C YLL032C 0.2 0.453814432 iYLL032C 0.471470298 0.538442041 0.520448496 YLL032C -- unknown -- unknown function YLL044W YLL044W 0.2 0.947811473 0.721189591 YLL044W -- unknown -- unknown function YLR024C UBR2 0.2 0.468900837 iYLR024C 0.183715985 0.494555134 0.404229848 UBR2 -- unknown -- similarity to ubiquitin-protein ligase (E3) Ubr1p YLR062C YLR062C 0.2 0.925051522 iYLR062C 0.720923065 0.439057837 0.331612487 YLR062C -- unknown -- unknown function YLR091W YLR091W 0.2 0.049323985 iYLR090W 0.26036184 0.2097141 0.224718762 YLR091W -- unknown -- unknown function YLR127C APC2 0.2 0.487487769 iYLR127C 0.628976541 0.749444582 0.260089823 "APC2 -- mitosis -- Component of anaphase-promoting complex, required for Clb2p degradation and for the metaphase-anaphase transition" YLR176C RFX1 0.2 0.343447656 iYLR176C 0.597985655 0.12383041 0.552795031 RFX1 -- unknown -- Repressor of DNA damage-inducible genes YLR266C YLR266C 0.2 0.795956784 iYLR266C 0.451181063 0.891939346 0.803685291 "YLR266C -- unknown -- similarity to transcription factors, has Zn[2]-Cys[6] fungal-type binuclear cluster domain in the N-terminal region" YLR345W YLR345W 0.2 0.850094448 iYLR344W 0.834022778 0.909120206 0.862503086 "YLR345W -- unknown -- similarity to rat fructose-2,6-bisphosphatase" YLR352W YLR352W 0.2 0.383599836 iYLR351C 0.405853704 0.701250422 0.70351273 YLR352W -- unknown -- unknown function YLR360W VPS38 0.2 0.588981094 iYLR359W 0.392826187 0.727787173 0.511562073 VPS38 -- vacuolar protein targeting -- vacuolar sorting YLR369W SSQ1 0.2 0.318605031 iYLR368W 0.748054214 0.836336707 0.675727999 SSQ1 -- DNA replication (mitochondrial) -- Mitochondrial heat shock protein 70 with possible involvement in mitochondrial DNA replication YLR381W YLR381W 0.2 0.375244863 iYLR380W 0.299286766 0.578235891 0.281681052 YLR381W -- unknown -- unknown function YLR392C YLR392C 0.2 0.731017607 iYLR392C 0.816586532 0.435434956 0.780615533 YLR392C -- unknown -- unknown function YLR404W YLR404W 0.2 0.707655561 iYLR403W 0.576180975 0.783839381 0.332703452 YLR404W -- unknown -- unknown function YML002W YML002W 0.2 0.76098605 iYML003W 0.259834871 0.945810056 0.431233363 YML002W -- unknown -- unknown function YML017W PSP2 0.2 0.493025603 iYML018C 0.304058164 0.339114302 0.693820456 "PSP2 -- mRNA splicing, putative -- High-copy suppressor of temperature-sensitive mutations in DNA polymerase alpha" YMR141C YMR141C 0.2 0.872369773 iYMR141C 0.52723689 0.693477247 0.383040936 YMR141C -- unknown -- unknown function YMR144W YMR144W 0.2 0.946208399 iYMR143W 0.967051274 0.728571429 0.581673655 "YMR144W -- unknown -- unknown function, probable coiled-coil protein" YMR168C CEP3 0.2 0.350221027 iYMR168C 0.36193271 0.65082846 0.250591416 CEP3 -- mitosis -- Component (subunit b) of Cbf3 kinetochore protein complex YMR172W HOT1 0.2 0.272868344 iYMR171C 0.386499444 0.68109497 0.551636073 HOT1 -- osmotic stress response (putative) -- Protein required with Msn1p for hyperosmotic stress-induced gene expression YMR180C CTL1 0.2 0.7534076 iYMR180C 0.11366619 0.89928525 0.07157775 CTL1 -- unknown -- RNA 5'-triphosphatase with manganese- or cobalt-dependent NTPase activities YMR213W CEF1 0.2 0.150574307 iYMR212C 0.209125343 0.105241504 0.431266903 "CEF1 -- unknown -- Pre-mRNA splicing factor, also required for transition into mitosis, member of family of eukaryotic Myb-like proteins related to S. pombe Cdc5p" YMR223W UBP8 0.2 0.612092282 iYMR222C 0.604416095 0.814465409 0.768127618 "UBP8 -- protein degradation, ubiquitin-mediated -- Putative ubiquitin-specific protease, ubiquitin C-terminal hydrolase" YNL043C YNL043C 0.2 0.556416182 iYNL043C YNLWsigma2 0.607668503 0.653233339 0.7716383 0.760223813 0.744096108 "YNL043C -- unknown -- unknown function, probably non-coding" YNL116W YNL116W 0.2 0.223973839 iYNL117W 0.300204108 0.789961014 0.432081856 YNL116W -- unknown -- unknown function YNL214W PEX17 0.2 0.386124287 iYNL215W 0.142458762 0.687963261 0.00742115 PEX17 -- peroxisome biogenesis -- Peroxisomal peripheral membrane peroxisome biogenesis (peroxin) YOL015W YOL015W 0.2 0.290000831 iYOL016C 0.530160256 0.369322152 0.837394319 "YOL015W -- unknown -- unknown function, induced during anaerobic growth" YOR005C DNL4 0.2 0.476849603 iYOR005C 0.476303285 0.667463476 0.486432562 "DNL4 -- DNA repair -- ATP-dependent DNA ligase IV, involved in non-homologous DNA end joining" YOR381W FRE3 0.2 0.571720709 iYOR380W-0 iYOR380W-1 0.385438436 0.177060344 0.308411215 0.280534966 0.09005738 "FRE3 -- unknown -- similarity to Fre2p, subject to regulation by iron" YPL216W YPL216W 0.2 0.214493359 iYPL217C 0.517485328 0.187420783 0.635314996 YPL216W -- unknown -- unknown function YPR026W ATH1 0.2 0.174649432 iYPR025C 0.53341201 0.471404372 0.585866527 "ATH1 -- trehalose metabolism -- Vacuolar acid trehalase (alpha, alpha-trehalase)" YPR095C SYT1 0.2 0.410219195 iYPR095C 0.349318408 0.190138576 0.174031103 "SYT1 -- unknown -- Guanine nucleotide exchange factor, contains a conserved Sec7p-domain" YPR171W YPR171W 0.2 0.025708205 iYPR170C 0.218322547 0.138495005 0.300676764 YPR171W -- unknown -- unknown function YDR426C YDR426C 0.1 43 0.410677449 iYDR426C 0.28111056 0.631764699 0.49324096 YDR426C -- unknown -- unknown function YAL067C SEO1 0.1 0.564221801 iYAL067C 0.464679791 0.557523575 0.629542278 SEO1 -- drug resistance -- similarity to Dal5p and members of allantoate permease family of major facilitator superfamily (MFS) YAR029W YAR029W 0.1 0.516657082 iYAR028W 0.546833318 0.514701105 0.854369721 "YAR029W -- unknown -- strong similarity to subtelomerically-encoded proteins such as Cos5p, Ybr302p, Cos3p, Cos1p, Cos4p, Cos8p, Cos6p, Cos9p, and Ycr007p" YBR033W YBR033W 0.1 0.851111159 iYBR032W 0.39617114 0.882282522 0.281723863 "YBR033W -- unknown -- similarity to transcription factors, has Zn[2]-Cys[6] fungal-type binuclear cluster domain in the N-terminal region" YBR040W FIG1 0.1 0.901645866 iYBR039W 0.549211046 0.953295152 0.736540501 FIG1 -- mating -- efficient mating YBR100W YBR100W 0.1 0.779693321 0.9 YBR100W -- unknown -- unknown function YBR117C TKL2 0.1 0.892077482 iYBR117C 0.987106709 0.796160361 0.476502446 TKL2 -- pentose phosphate cycle -- Transketolase 2 YBR138C HDR1 0.1 0.305865744 iYBR138C 0.703276186 0.499136016 0.661053472 HDR1 -- meiosis -- meiotic segregation YBR223C YBR223C 0.1 0.41160638 0.695939413 "YBR223C -- unknown -- Tyrosyl-DNA phosphodiesterase, involved in DNA repair" YCL004W PGS1 0.1 0.487163129 iYCL005W 0.024244146 0.339669217 0.037110179 "PGS1 -- phospholipid metabolism -- Phosphatidylglycerophosphate synthase, the first enzyme of cardiolipin biosynthetic pathway" YCL014W BUD3 0.1 0.361031655 iYCL016C 0.276130391 0.669066016 0.710935571 "BUD3 -- cell polarity -- localized at the neck filament ring required for axial budding, may provide a memory of previous bud site" YCL074W 0.1 0.985510202 YCLWTy5-1B iYCL075W 0.978790271 0.974260414 0.676764422 0.444269741 0.068773234 YCR007C YCR007C 0.1 0.752976061 iYCR007C tN(GUU)C 0.813106626 0.48500876 0.850225588 0.927712801 0.175819534 "YCR007C -- unknown -- strong similarity to subtelomerically-encoded proteins such as Cos5p, Ybr302p, Cos3p, Cos1p, Cos4p, Cos8p, Cos6p, Cos9p" YCR091W KIN82 0.1 0.175026254 iYCR090C-0 iYCR090C-1 0.599159867 0.081383281 0.441739824 0.77014295 0.091335473 KIN82 -- unknown -- Serine/threonine protein kinase with unknown role YCR098C GIT1 0.1 0.148659921 iYCR098C-0 iYCR098C-1 0.457587378 0.58117462 0.198882682 0.557063049 0.28875282 "GIT1 -- unknown -- inositol metabolism, member of phosphate" YCR099C YCR099C 0.1 0.188889861 0.538092917 YCR099C -- unknown -- strong similarity to Pep1pprobably a fragmented coding region of a pseudogene YDL149W APG9 0.1 0.081835843 iYDL150W 0.172503659 0.641929499 0.372725796 APG9 -- autophagy -- starvation-induced autophagy YDL220C CDC13 0.1 0.340046991 iYDL220C 0.658118106 0.418955213 0.720577559 "CDC13 -- cell cycle, G2/M -- Telomere-binding protection of telomere and required for access of telomerase to the chromosomal terminus" YDL238C YDL238C 0.1 0.388882719 iYDL238C 0.594176005 0.831453432 0.811728644 YDL238C -- unknown -- Putative guanine deaminase YDR024W YDR024W 0.1 0.985867492 iYDR023W 0.954446541 0.755414527 0.719965974 YDR024W -- unknown -- unknown function YDR223W YDR223W 0.1 0.497906328 iYDR222W 0.487369509 0.863928782 0.790422985 YDR223W -- unknown -- unknown function YDR263C DIN7 0.1 0.635731878 iYDR263C 0.396718957 0.785238213 0.539033457 DIN7 -- DNA repair (putative) -- Mitochondrial inner membrane nuclease with a role in stabilizing the mitochondrial genomeexpression is induced by DNA damage YDR313C PIB1 0.1 0.37439045 iYDR313C 0.234020001 0.417439703 0.207195191 "PIB1 -- signaling -- Phosphatidylinositol(3)-phosphate binding proteinhas similarity to Pep7p/Vac1p, Fab1p and human endosomal protein" YDR359C VID21 0.1 0.186298341 0.684604624 VID21 -- unknown -- unknown function YDR369C XRS2 0.1 0.372080028 iYDR369C 0.385310421 0.695419103 0.186556916 XRS2 -- DNA repair and recombinations -- DNA-repair and meiotic recombination YDR417C YDR417C 0.1 0.975209116 0.966161213 YDR417C -- unknown -- unknown function YDR491C YDR491C 0.1 0.66270034 0.929050279 YDR491C -- unknown -- similarity to Yol002p YDR501W PLM2 0.1 0.949871441 iYDR500C 0.989216992 0.832402235 0.149021663 PLM2 -- plasmid maintenance (putative) -- plasmid maintenance YEL014C YEL014C 0.1 0.651011901 iYEL014C 0.674067952 0.687649615 0.56691135 YEL014C -- unknown -- unknown function YEL070W YEL070W 0.1 0.274023655 iYEL071W-0 iYEL071W-1 0.538710491 0.368806203 0.680470512 0.512130886 0.406058653 YEL070W -- unknown -- similarity to E. coli D-mannonate oxidoreductaseYel070p and Ynr073p are identical proteins YEL076WC 0.1 YER015W FAA2 0.1 0.822262948 iYER014W 0.514166024 0.610213184 0.404070231 "FAA2 -- fatty acid metabolism -- Acyl-CoA synthetase (long-chain fatty acid CoA ligase, fatty acid activator 2), activates endogenous but not imported fatty acids, provides substrates for N-myristoylation" YER038C YER038C 0.1 0.715255479 iYER038C 0.450088171 0.890025782 0.332690303 YER038C -- unknown -- unknown function YER066C-A YER066C-A 0.1 0.616323247 0.768867925 YER066C-A -- unknown -- unknown function YER096W SHC1 0.1 0.667041354 iYER095W 0.552290756 0.938014832 0.178930567 SHC1 -- sporulation -- cell wall chitin synthesis or deposition YER097W YER097W 0.1 0.691588606 iYER096W YERWdelta12 0.351544251 0.459494063 0.536062378 0.17507251 0.55852356 YER097W -- unknown -- unknown function YER098W UBP9 0.1 0.242445024 0.492507251 "UBP9 -- protein degradation, ubiquitin-mediated -- Ubiquitin C-terminal hydrolase, has similarity to Ubp13p" YFR015C GSY1 0.1 0.34594462 iYFR015C 0.468575856 0.439408707 0.291229909 GSY1 -- glycogen metabolism -- UDP-glucose-starch glucosyltransferase (glycogen synthetase) isoform 1 YGL059W YGL059W 0.1 0.869653435 iYGL060W 0.440735048 0.96257159 0.195773171 YGL059W -- unknown -- similarity to human branched-chain alpha-ketoacid dehydrogenase kinasetranscription induced by the drug FK506 in a GCN4-dependent manner YGL146C YGL146C 0.1 0.962517779 iYGL146C 0.449903617 0.662330407 0.267080745 YGL146C -- unknown -- similarity to Bunyamwera virus RNA-directed RNA polymerase YGL180W APG1 0.1 0.325180436 iYGL181W 0.148921433 0.841457653 0.255441845 APG1 -- autophagy -- Serine/threonine protein kinase involved in induction of autophagy after nutrient limitation YGL214W YGL214W 0.1 0.246913522 iYGL215W 0.026510313 0.304418454 0.007734451 YGL214W -- unknown -- unknown function YGL251C HFM1 0.1 0.360542539 iYGL251C 0.05512107 0.572306464 0.17047087 "HFM1 -- unknown -- DNA/RNA helicase involved in meiotic recombination, member of DExH-box type helicase family with Ski2p and Brr2p" YGL263W COS12 0.1 0.952080298 TEL6R iYGLWomega1-0 0.995487365 0.971712473 0.879406308 0.007743809 0.54737351 COS12 -- unknown -- Member of COS family of subtelomerically-encoded proteins YGR016W YGR016W 0.1 0.683764241 iYGR015C 0.41131974 0.821772402 0.383909853 YGR016W -- unknown -- unknown function YGR212W YGR212W 0.1 0.667321657 iYGR211W 0.486310428 0.716141002 0.222931547 YGR212W -- unknown -- unknown function YGR288W MAL13 0.1 0.338083076 iYGR287C 0.154848632 0.671688688 0.422118254 "MAL13 -- maltose utilization -- Maltose pathway regulatory protein, contains a Zn[2]-Cys[6] fungal-type binuclear cluster domain" YHL024W NOS1 0.1 0.31178485 iYHL025W 0.087743894 0.719223332 0.150660651 "NOS1 -- sporulation (putative) -- sporulation and formation of meiotic spindle, has two RNA recognition motif (RRM) domains" YHR044C DOG1 0.1 0.611365362 iYHR044C 0.550011383 0.55131684 0.772283617 DOG1 -- 2-deoxyglucose resistance -- 2-Deoxyglucose-6-phosphate phosphatase YHR157W REC104 0.1 0.520209005 iYHR156C 0.318210763 0.880939902 0.549790525 "REC104 -- meiosis, recombination -- Meiosis-specific protein, mutants are defective in synaptonemal complex formation and have reduced recombination" YHR213W YHR213W 0.1 0.179964915 iYHR212C 0.399400827 0.313785593 0.5414301 "YHR213W -- unknown -- similarity to the N-terminus of Flo1p and identical to Yar062p, probable pseudogene" YIL029C YIL029C 0.1 0.405960652 iYIL029C 0.362363834 0.580021394 0.649633835 YIL029C -- unknown -- unknown function YIL073C SPO22 0.1 0.591573772 iYIL073C 0.584694544 0.707809224 0.582105378 "SPO22 -- sporulation -- meiosis and sporulation, has cecropin family signature" YIL092W YIL092W 0.1 0.245880073 iYIL093C 0.201256967 0.344688554 0.181124107 YIL092W -- unknown -- unknown function YIL097W YIL097W 0.1 0.263691422 iYIL098C 0.421690669 0.594217024 0.476526966 YIL097W -- unknown -- unknown function YIR039C YPS6 0.1 0.44694315 iYIR039C 0.867930507 0.545646524 0.734715708 "YPS6 -- protein degradation -- Yapsin 6, GPI-anchored aspartyl protease" YJL023C PET130 0.1 0.323109691 0.718480277 "PET130 -- protein synthesis, mitochondrial -- mitochondrial protein synthesis" YJL047C RTT101 0.1 0.508558953 iYJL047C 0.72290539 0.338148444 0.561096026 "RTT101 -- transposition (putative) -- cullin family, with similarity to Cdc53p" YJL085W EXO70 0.1 0.501773894 0.465662511 EXO70 -- secretion -- Component of exocyst complex (70 kDa) required for exocytosis YJL107C YJL107C 0.1 0.428089237 iYJL107C 0.55094345 0.822618375 0.747050921 YJL107C -- unknown -- unknown function YJL114W 0.1 0.65383421 iYJL115W 0.387434987 0.876705653 0.392824817 YJL150W YJL150W 0.1 0.527047207 iYJL151C 0.125789218 0.060734238 YJL150W -- unknown -- unknown function YJR011C YJR011C 0.1 0.464281717 iYJR011C 0.435977738 0.767241379 0.548177405 YJR011C -- unknown -- unknown function YKL093W MBR1 0.1 0.296453634 iYKL094W 0.462217412 0.763329838 0.317676442 MBR1 -- mitochondrial biogenesis -- mitochondrial biogenesis YKL153W YKL153W 0.1 0.874659625 iYKL154W itR(UCU)K 0.457179861 0.778190123 0.647227637 0.302250544 0.283372761 "YKL153W -- unknown -- unknown function, highly questionable ORF" YKL162C YKL162C 0.1 0.280377959 iYKL162C 0.114478656 0.790370974 0.297868623 YKL162C -- unknown -- unknown function YLL016W 0.1 0.478118192 iYLL017W 0.080581116 0.3471668 0.097525938 YLR047C YLR047C 0.1 0.904682118 iYLR047C 0.984267245 0.790674118 0.287681649 YLR047C -- unknown -- unknown function YLR080W YLR080W 0.1 0.254029874 iYLR079W 0.358883672 0.660577635 0.201673164 YLR080W -- unknown -- similarity to Emp47p YLR122C YLR122C 0.1 0.341240012 0.70866903 YLR122C -- unknown -- unknown function YLR149C YLR149C 0.1 0.195726081 iYLR149C 0.239450312 0.088247157 YLR149C -- unknown -- unknown function YLR329W REC102 0.1 0.802685972 iYLR328W 0.42586564 0.957167057 0.337614059 "REC102 -- meiosis, recombination -- Meiotic recombination protein, required for early meiotic events and for formation of synaptonemal complex but not required for mitosis" YLR358C YLR358C 0.1 0.23841359 iYLR358C 0.653089316 0.206780219 0.627998943 YLR358C -- unknown -- unknown function YLR465C YLR465C 0.1 0.938936872 0.943212067 "YLR465C -- unknown -- unknown function, questionable ORF" YML042W CAT2 0.1 0.246123039 iYML043C 0.244048894 0.868514341 0.572458167 "CAT2 -- fatty acid transport -- Carnitine O-acetyltransferase, peroxisomal and mitochondrial" YML050W YML050W 0.1 0.840698622 iYML051W 0.608696377 0.938291522 0.533119297 YML050W -- unknown -- weak similarity to potato sucrose cleavage protein YMR106C YKU80 0.1 0.379044884 iYMR106C itK(CUU)M 0.685331448 0.229834575 0.463450703 0.710441508 0.453416149 "YKU80 -- DNA repair -- Component of DNA end-joining repair pathway, acts in complex with Yku70p" YMR169C ALD3 0.1 0.4688151 iYMR169C 0.246950641 0.507501995 0.527603075 "ALD3 -- ethanol utilization -- Cytoplasmic, stress inducible aldehyde dehydrogenase, probable isoform of Ald2p" YNL012W SPO1 0.1 0.738632018 iYNL013C 0.575759434 0.763766959 0.547354563 SPO1 -- meiosis (spor.) -- Transcriptional regulator involved in sporulationhas strong similarity to phospholipase B enzymes YNL033W YNL033W 0.1 0.243003348 iYNL034W 0.194257746 0.298281986 0.250361761 YNL033W -- unknown -- unknown function YNL171C YNL171C 0.1 0.681757928 0.765325434 "YNL171C -- unknown -- unknown function, questionable ORF" YNR075W COS10 0.1 0.95240408 iYNR074C 0.326374293 0.224415205 COS10 -- unknown -- Member of COS family of subtelomerically-encoded proteins YOL104C NDJ1 0.1 0.56473826 iYOL104C iYOLWdelta5 0.162452487 0.226478275 0.929959446 0.401843684 0.045360079 "NDJ1 -- meiosis, chromosome segregation -- Meiotic telomere protein, involved in normal chromosomal synapsis and segregation" YOL134C YOL134C 0.1 0.81454783 0.73283859 YOL134C -- unknown -- unknown function YOL153C 0.1 0.551652062 iYOL153C-0 iYOL153C-1 0.401735383 0.663871419 0.289879792 YOR156C NFI1 0.1 0.144596687 iYOR156C 0.558697882 0.212318351 0.401117318 "NFI1 -- unknown -- interacts with Cdc12p, by two-hybrid assay" YOR200W YOR200W 0.1 0.208202934 0.184399451 YOR200W -- unknown -- unknown function YPL014W YPL014W 0.1 0.13183993 iYPL015C 0.272013806 0.063567515 0.280615533 YPL014W -- unknown -- unknown function YPL060W YPL060W 0.1 0.274602384 iYPL061W 0.466009359 0.423703113 0.061408106 YPL060W -- unknown -- similarity to Mrs2p YPL209C IPL1 0.1 0.121538218 iYPL209C 0.588736813 0.12666731 0.405098008 "IPL1 -- mitosis, chromosome segregation -- Serine/threonine protein kinase of mitotic spindle, involved in chromosome segregation" YPL222W YPL222W 0.1 0.488799661 iYPL223C 0.349179495 0.427387914 0.473846654 YPL222W -- unknown -- unknown function YPL230W USV1 0.1 0.097874216 iYPL231W 0.729463253 0.148060797 0.735461339 "USV1 -- unknown -- Putative finger transcripton factor, has a two tandem C2H2-type zinc fingers" YPL251W YPL251W 0.1 0.512303707 0.159116754 YPL251W -- unknown -- unknown function YPL277C YPL277C 0.1 0.213286362 iYPL277C 0.469513258 0.448899371 0.488032844 YPL277C -- unknown -- unknown function YPR083W YPR083W 0.1 0.291826218 iYPR082C 0.203729839 0.502474062 0.118959108 YPR083W -- unknown -- weak similarity to Halobacterium holobium cell surface glycoprotein precursor YPR130C YPR130C 0.1 0.900760887 iYPR130C 0.897333398 0.129903848 0.442360217 YPR130C -- unknown -- unknown functionquestionable ORF YAL004W YAL004W 21 0.750621198 iYAL007C YALCdelta2 0.367046351 0.717986077 0.750174703 0.615041929 0.463905898 YAL004W -- unknown -- unknown functionquestionable ORF YAL018C YAL018C 0.610924983 iYAL018C 0.217685725 0.75722872 0.056773879 "YAL018C -- unknown -- unknown function, has 5 potential transmembrane segments" YAL035W-A 16 YAL043C-A YAL043C-A 0.42622707 0.51583971 YAL043C-A -- unknown -- unknown function YAL045C YAL045C 22 0.331957261 iYAL045C 0.283413954 0.494964263 0.463664196 YAL045C -- unknown -- unknown function YAL063C FLO9 0.151505301 iYAL063C-0 iYAL063C-1 0.479264792 0.542969692 0.247721223 0.540702314 0.851875499 "FLO9 -- flocculation -- strong similarity to flocculation proteins Flo1p, Flo5p, and Flo10p" YAL064W YAL064W 0.599105382 iYAL064C-A-0 iYAL064C-A-1 0.441434199 0.304044788 0.810088044 0.67097141 0.648888173 YAL064W -- unknown -- unknown function YAL065C YAL065C 0.402604798 iYAL065C 0.363443319 0.701056707 0.446448524 YAL065C -- unknown -- similarity to Flo1p YAL065C-A 78 YAL066W YAL066W 14 0.732157811 iYAL067C 0.464679791 0.854828412 0.629542278 YAL066W -- unknown -- unknown function YAL069W YAL069W 0.997369965 0.039984038 YAL069W -- unknown -- unknown functionlikely not a real ORF YAR030C YAR030C 18 0.750178886 0.645766477 "YAR030C -- unknown -- unknown function, probable non-coding ORF" YAR037W YAR040C YAR043C YAR047C YAR047C 20 0.680514607 iYAR047C-0 iYAR047C-1 0.466145356 0.496632856 0.687238157 0.737037857 0.808936065 "YAR047C -- unknown -- unknown function, has potential nuclear targeting sequence" YAR052C YAR061W YAR061W 23 0.64544995 iYAR060C 0.558307011 0.862889066 0.898960364 "YAR061W -- unknown -- similarity to N-terminus of Flo1p, probable pseudogene" YAR062W YAR062W 0.347744518 iYAR061W 0.441285202 0.506289308 0.634547212 "YAR062W -- unknown -- similarity to the N-terminus of Flo1p and identical to Yhr213p, probable pseudogene" YAR064W YAR064W 0.748337672 iYAR062W 0.201233515 0.769577828 0.517033543 YAR064W -- unknown -- unknown function YAR070C YAR070C 22 0.561317698 iYAR070C 0.677761128 0.492098962 0.561670161 "YAR070C -- unknown -- unknown function, has potential mitochondrial transit peptide" YAR074C YBL012C YBL012C 0.551878045 0.863906359 YBL012C -- unknown -- unknown function YBL013W FMT1 0.858007119 iYBL014C 0.620692921 0.877999324 0.333951763 FMT1 -- unknown -- Mitochondrial methionyl-tRNA transformylase YBL044W YBL044W 0.278816055 iYBL045C 0.759867416 0.874485763 0.514985498 YBL044W -- unknown -- unknown function YBL062W YBL062W 25 0.594667133 iYBL063W 0.690477583 0.451740251 0.389524436 "YBL062W -- unknown -- unknown function, probable non-coding ORF" YBL065W YBL065W 0.594391482 0.257573316 YBL065W -- unknown -- unknown functionquestionable ORF YBL070C YBL070C 0.889288585 0.674018955 YBL070C -- unknown -- unknown function YBL073W YBL073W 16 0.500825792 0.277380071 YBL073W -- unknown -- unknown function YBL074C AAR2 29 0.373878117 0.350225588 "AAR2 -- mRNA splicing, MATa1 -- splicing MATA1 pre-mRNA, not required for splicing various other pre-mRNAs" YBL097W BRN1 0.332708184 iYBL098W 0.557511155 0.345272904 0.309057114 BRN1 -- chromosome maintenance -- Subunit of condensin protein complex required for proper chromosome condensation and segregation YBL100C YBL100C 0.570024571 0.828172386 YBL100C -- unknown -- unknown functionquestionable ORF YBL108W YBL108W 0.953945221 iYBL109W-0 iYBL109W-1 0.998446142 0.97328505 0.899491813 0.271401118 0.539566024 YBL108W -- unknown -- unknown function YBR006W UGA5 17 0.698489974 iYBR005W 0.460724447 0.981550113 0.334636872 UGA5 -- unknown -- Probable succinate semialdehyde dehydrogenase YBR019C GAL10 0.446485177 iYBR019C 0.431727605 0.854521517 0.778898121 GAL10 -- galactose metabolism -- UDP-glucose 4-epimerase YBR045C GIP1 14 0.833169336 iYBR045C 0.530580961 0.661372706 GIP1 -- glucose repression -- Glc7p-interacting proteinpossible regulatory subunit for the PP1 family protein phosphatases YBR051W YBR051W 0.688681463 0.744134078 YBR051W -- unknown -- unknown functionquestionable ORF YBR064W YBR064W 0.866482412 0.792046463 YBR064W -- unknown -- unknown function YBR076W ECM8 25 0.480878401 iYBR075W 0.634379879 0.636096715 0.735044845 ECM8 -- cell wall biogenesis -- Protein possibly involved in cell wall structure or biosynthesis YBR098W MMS4 16 0.37690732 iYBR097W 0.697723906 0.289067576 0.491939346 "MMS4 -- methylmethanesulfonate resistance -- normal repair of damage by the DNA alkylating agent methylmethanesulfonate (MMS), not required for repair of UV or X-ray damage, has similarity to clathrin heavy chain, may be a transcriptional activator" YBR108W YBR108W 22 0.16239584 iYBR107C 0.493075036 0.216725749 0.400466693 "YBR108W -- unknown -- clusters of glutamine and proline residuessimilar clusters are present in wheat glutenin, secalin, and Drosophila mastermind protein" YBR116C YBR116C 0.78554498 0.53772731 YBR116C -- unknown -- unknown function YBR124W YBR124W 0.763244448 0.92136642 YBR124W -- unknown -- unknown functionquestionable ORF YBR134W YBR134W 30 0.858203256 0.55932887 YBR134W -- unknown -- unknown function YBR144C YBR144C 33 0.489032865 iYBR144C 0.655678305 0.874889086 0.63619466 YBR144C -- unknown -- unknown function YBR147W YBR147W 20 0.602205521 iYBR146W 0.549577978 0.956010313 0.84827044 "YBR147W -- unknown -- unknown function, has 7 potential transmembrane segmentstranscription induced by the drug FK506 in a GCN4-dependent manner" YBR152W SPP381 17 0.137236687 iYBR151W 0.52831067 0.151360232 0.503142121 "SPP381 -- mRNA processing (putative) -- efficient pre-mRNA splicing, component of U4/U6.U5 tri-snRNP complex" YBR174C YBR174C 34 0.353437424 0.615068162 YBR174C -- unknown -- unknown function YBR178W YBR178W 0.417294962 0.69265757 YBR178W -- unknown -- unknown function YBR182C SMP1 0.97374093 iYBR182C 0.592805753 0.972043184 0.8111505 "SMP1 -- cell wall organization -- Transcription factor of MADS (Mcm1p, Agamous, Deficiens, SRF) box family" YBR184W YBR184W 16 0.385170903 iYBR183W 0.607858038 0.67810071 0.12985806 YBR184W -- unknown -- unknown function YBR186W PCH2 12 0.630780205 iYBR185C 0.339734032 0.835033 0.107045387 "PCH2 -- meiosis, checkpoint -- cell cycle arrest at the pachytene stage of meiosis in a zip1 mutant, has similarity to Rpt5p and NSF vesicular fusion protein and other members of AAA family of ATPases" YBR209W YBR209W 0.495548237 iYBR208C 0.247330995 0.400178687 0.621032142 YBR209W -- unknown -- unknown function YBR224W YBR224W 0.465805592 0.395789658 YBR224W -- unknown -- unknown function YBR232C YBR232C 23 0.234217614 0.164650704 YBR232C -- unknown -- unknown functionquestionable ORF YBR240C THI2 19 0.32719998 iYBR240C 0.20822232 0.71245012 0.467941999 THI2 -- thiamine biosynthesis -- Zinc-finger regulatory protein for thiamine pyrophosphokinase (THI80) expression YBR250W YBR250W 16 0.546381739 iYBR249C 0.175940978 0.202304222 YBR250W -- unknown -- unknown function YBR266C YBR266C 0.202297521 0.425903069 YBR266C -- unknown -- unknown function YBR277C YBR277C 0.489793503 0.597525938 "YBR277C -- unknown -- unknown function, questionable ORF" YBR284W YBR284W 52 0.327714427 iYBR283C 0.371552176 0.686250309 0.38531514 YBR284W -- unknown -- similarity to AMP deaminase YBR285W YBR285W 14 0.154055084 iYBR284W 0.311652661 0.451904879 0.346616117 YBR285W -- unknown -- unknown function YBR294W SUL1 0.429304615 iYBR293W 0.251499114 0.661306043 0.373078267 "SUL1 -- transport -- Sulfate permease (high-affinity sulfate transporter), member of sulfate permease family of membrane transporters" YBR299W MAL32 23 0.512156999 iYBR298C 0.759861897 0.785231497 0.834206848 MAL32 -- maltose metabolism -- Maltase YCL004W PGS1 0.487163129 iYCL005W 0.024244146 0.339669217 0.037110179 "PGS1 -- phospholipid metabolism -- Phosphatidylglycerophosphate synthase, the first enzyme of cardiolipin biosynthetic pathway" YCL022C YCL022C 0.296453662 iYCL022C tE(UUC)C 0.700121395 0.793162827 0.104007241 0.546458739 0.541089268 YCL022C -- unknown -- unknown function YCL026C 29 YCL041C YCL041C 40 0.374699508 0.147187282 YCL041C -- unknown -- similarity to human papilloma virus (HPV) E6 protein YCL046W YCL046W 0.260252496 0.137465896 YCL046W -- unknown -- unknown function YCL048W YCL048W 0.482246806 iYCL049C 0.676930362 0.740905058 0.726681311 YCL048W -- unknown -- similarity to Ecm33p and Sps2p YCL058C YCL058C 24 0.623297146 iYCL058C 0.423799709 0.3924703 0.340143655 YCL058C -- unknown -- unknown function YCL065W YCL065W 0.990568844 0.538840042 YCL065W -- unknown -- unknown functionquestionable ORF YCL069W YCL069W 0.97877752 iYCL073C 0.862365535 0.915802075 0.126576217 YCL069W -- unknown -- Member of multidrug-resistance 14 spanner family of major facilitator superfamily (MFS-MDR) YCL075W 0.986578307 YCLWTy5-1A 0.990963 0.580977908 0.43955276 YCL076W YCL076W 0.994100511 YCLWomega1 0.993458076 0.709445834 0.210607537 YCL076W -- unknown -- unknown function YCR001W YCR001W 0.803332244 YCL001W-A iYCL001W-A 0.524567961 0.435780598 0.466161168 0.646551724 0.389412998 YCR001W -- unknown -- unknown function YCR010C YCR010C 0.458096227 iYCR010C 0.40576166 0.557541899 0.232003192 "YCR010C -- unknown -- unknown function, has strong similarity to Ydr384p and Ynr002p" YCR022C YCR022C 0.118099401 iYCR022C 0.665809557 0.204353476 0.698717432 YCR022C -- unknown -- unknown function YCR040W ALPHA1 0.993050575 iYCR039C 0.984495399 0.677306693 0.232972957 "ALPHA1 -- transcription -- Regulatory protein Alpha1p, with Mcm1p, activates alpha-specific genes" YCR040W ALPHA1 0.993050575 iYCR039C 0.984495399 0.677306693 0.232972957 "ALPHA1 -- transcription -- Regulatory protein Alpha1p, with Mcm1p, activates alpha-specific genes" YCR041W YCR041W 45 0.984383181 0.564168751 YCR041W -- unknown -- unknown function YCR045C YCR045C 0.658875923 iYCR045C 0.802141549 0.803032721 0.702542582 YCR045C -- unknown -- similarity to protease B (Prb1p) and subtilisin family proteases YCR049C YCR049C 0.744674009 0.421934365 YCR049C -- unknown -- unknown function YCR050C YCR050C 21 0.81968887 iYCR050C 0.871142118 0.571747805 0.823344358 YCR050C -- mitochondrial function (putative) -- mitochondrial function YCR056W 43 YCR064C YCR064C 0.258143807 0.099415205 YCR064C -- unknown -- unknown function YCR074C YCR081W SRB8 35 0.453168139 iYCR079W 0.423723309 0.825857941 0.407084612 SRB8 -- transcription -- Component of RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex YCR085W YCR085W 16 0.493260942 iYCR084C 0.310011711 0.364523675 0.10001747 YCR085W -- unknown -- unknown function YCR100C YCR100C 0.544155646 iYCR100C 0.654397575 0.709796971 0.913906365 YCR100C -- unknown -- similarity to Pep1pprobably represents a fragmented coding region of a pseudogene YCR101C YCR101C 0.520232847 iYCR101C 0.187849357 0.835953878 0.267278532 "YCR101C -- unknown -- similarity to Pep1p, probably represents a fragmented coding region of a pseudogene" YCR107W AAD3 15 0.911900621 iYCR106W 0.676637311 0.720658224 0.149371069 "AAD3 -- unknown -- Putative aryl alcohol dehydrogenase, homolog of Phanerochaete chrysosporium (white-rot fungus) ligninolytic aryl-alcohol dehydrogenase (PHAAD)" YDL011C YDL011C 52 0.471264368 0.711338532 YDL011C -- unknown -- unknown function YDL016C YDL016C 0.674761211 iYDL016C 0.765054048 0.709233 0.870511349 YDL016C -- unknown -- unknown function YDL023C YDL023C 0.97124243 0.103598882 YDL023C -- unknown -- unknown function YDL024C YDL024C 9 0.461464712 iYDL024C itA(AGC)D 0.862300561 0.97702593 0.787561146 0.500402836 0.159492282 YDL024C -- unknown -- similarity to acid phosphatases YDL026W YDL026W 0.252220294 0.07662178 YDL026W -- unknown -- unknown functionquestionable ORF YDL032W YDL032W 0.453493046 0.229971333 YDL032W -- unknown -- unknown function YDL034W YDL034W 0.840628618 0.335984283 YDL034W -- unknown -- unknown function YDL037C YDL037C 11 0.042865545 iYDL037C-0 iYDL037C-1 0.411886053 0.293190532 0.045032105 0.815501128 0.614197531 "YDL037C -- unknown -- similarity to glucan 1,4-alpha-glucosidase" YDL049C KNH1 19 0.616966165 iYDL049C 0.531112748 0.614405414 0.442904433 KNH1 -- cell wall biogenesis -- Putative secreted similarity to Kre9p YDL062W YDL062W 23 0.896695876 0.674427973 "YDL062W -- unknown -- unknown function, questionable ORF" YDL068W YDL068W 79 0.234563868 0.054842333 YDL068W -- unknown -- unknown function YDL071C YDL071C 0.559824822 0.38056447 YDL071C -- unknown -- unknown function YDL085W YDL085W 19 0.556220764 iYDL086W 0.363791553 0.691022793 0.213341927 YDL085W -- unknown -- Mitochondrial NADH dehydrogenase that catalyzes the oxidation of cytosolic NADH YDL087C LUC7 14 0.341493291 iYDL087C 0.43022246 0.380503145 0.417226866 LUC7 -- mRNA processing (putative) -- exit from mitosis YDL096C YDL096C 21 0.450327476 0.45566176 YDL096C -- unknown -- unknown function YDL114W YDL114W 0.523386109 iYDL115C 0.264362105 0.699132216 0.387345679 YDL114W -- unknown -- similarity to proteins of short-chain alcohol dehydrogenase family YDL118W YDL118W 13 0.475519564 0.243058467 YDL118W -- unknown -- unknown functionquestionable ORF YDL151C YDL151C 0.110338523 0.261030895 YDL151C -- unknown -- unknown function YDL162C YDL162C 0.316518029 0.262527427 YDL162C -- unknown -- unknown function YDL163W YDL163W 24 0.618874568 0.87295318 YDL163W -- unknown -- unknown function YDL172C YDL172C 15 0.201025738 iYDL172C 0.440802728 0.232966457 0.060814046 YDL172C -- unknown -- unknown function YDL187C YDL187C 0.984311186 0.749187784 YDL187C -- unknown -- unknown functionquestionable ORF YDL196W YDL196W 30 0.192045754 iYDL197C 0.336763405 0.150768693 0.336936356 YDL196W -- unknown -- unknown function YDL199C YDL199C 0.405255349 iYDL199C 0.502963384 0.900877893 0.314373187 YDL199C -- unknown -- Member of hexose transporter family of major facilitator superfamily (MFS) YDL218W YDL218W 0.108246736 iYDL219W 0.248495206 0.297582398 0.636715214 "YDL218W -- unknown -- unknown function induced during aerobic growth, has weak similarity to Ynr061p" YDL221W YDL221W 0.127401866 iYDL222C 0.516233873 0.265871737 0.50862069 YDL221W -- unknown -- unknown function YDL222C YDL222C 0.173449711 iYDL222C 0.516233873 0.484854362 0.50862069 YDL222C -- unknown -- similarity to Sur7p YDL239C YDL239C 30 0.910142298 iYDL239C 0.365611889 0.307182761 0.410087013 "YDL239C -- unknown -- Putative coiled-coil protein, has similarity to S. cerevisiae Cnm67p, a spindle pole body and nuclear migration protein" YDL242W YDL242W 30 0.299982733 iYDL243C 0.382350274 0.312779044 0.580625437 YDL242W -- unknown -- unknown function YDL245C HXT15 0.234019853 iYDL245C-0 iYDL245C-1 0.49437682 0.345011897 0.39034805 0.764179826 0.703241157 "HXT15 -- transport -- member of sugar transporter family of major facilitator superfamily (MFS), has strong similarity to Hxt16p, Hxt17p, Hxt13p, and Hxt7p" YDL247W YDL247W 0.300777213 iYDL248W-0 iYDL248W-1 0.877210415 0.388820914 0.551057352 0.489305666 0.614261515 "YDL247W -- unknown -- similarity to maltose permeases including Yjr160p, Mal31p, Mal61p, member of hexose transporter family of major facilitator superfamily (MFS)" YDR009W GAL3 26 0.522620428 iYDR008C 0.574483479 0.780377997 0.626522546 GAL3 -- galactose metabolism -- Regulatory rapid induction of galactose pathwaybinds Gal80p YDR010C YDR010C 0.140558641 iYDR010C 0.470414755 0.203380215 0.444828437 YDR010C -- unknown -- unknown function YDR015C YDR015C 0.411948831 iYDR015C 0.366577728 0.600319234 YDR015C -- unknown -- unknown function YDR018C YDR018C 0.470234422 iYDR018C 0.765334834 0.777424989 0.688028731 YDR018C -- unknown -- Putative acyltransferase with similarity to Ybr042p YDR029W YDR029W 0.791036555 iYDR028C 0.63661389 0.664938698 0.591768884 YDR029W -- unknown -- unknown function YDR048C 0.599174679 0.347222222 YDR053W YDR053W 15 0.368701917 0.436764585 YDR053W -- unknown -- unknown function YDR095C YDR095C 0.728294694 iYDR095C 0.412909881 0.732658603 0.532721468 YDR095C -- unknown -- unknown function YDR102C YDR102C 0.682441985 iYDR102C 0.334157515 0.802952913 0.295379251 YDR102C -- unknown -- unknown function YDR106W ARP10 41 0.603041837 iYDR105C 0.173825663 0.691449814 0.19479385 ARP10 -- cytoskeleton (putative) -- similarity to actin and actin-related proteins Arp1p-Arp9p YDR112W 0.676264501 0.622338628 YDR114C YDR114C 12 0.152591413 0.26893329 YDR114C -- unknown -- unknown function YDR122W KIN1 18 0.09158074 iYDR121W 0.174322034 0.465893195 0.240621832 "KIN1 -- unknown -- Serine/threonine protein kinase, related to Kin2p and S. pombe KIN1" YDR124W YDR124W 0.169490668 iYDR123C 0.166241562 0.41281988 0.366799681 YDR124W -- unknown -- unknown function YDR125C ECM18 0.669558751 iYDR125C 0.608321271 0.923791822 0.871420505 ECM18 -- cell wall biogenesis -- Protein possibly involved in cell wall structure or biosynthesis YDR136C YDR136C 0.780303645 0.820924417 YDR136C -- unknown -- unknown function YDR149C 0.110290277 0.181404629 YDR187C 0.972991508 0.406384677 YDR193W 18 0.789378612 0.916693522 YDR199W 0.712315502 iYDR198C 0.364130876 0.654513189 0.258207631 YDR203W 0.394752042 0.659856345 YDR215C YDR215C 0.243834382 iYDR215C 0.454536807 0.479976343 0.425059142 YDR215C -- unknown -- unknown function YDR218C SPR28 0.218769038 iYDR218C 0.429901247 0.568144899 0.551827055 SPR28 -- sporulation -- Septin-related protein expressed during sporulation YDR230W 0.581376618 iYDR229W 0.478067415 0.530747729 0.164086193 YDR241W YDR241W 21 0.470716754 0.17960067 YDR241W -- unknown -- unknown function YDR256C CTA1 17 0.284648577 iYDR256C 0.293230544 0.927968651 0.126482213 "CTA1 -- oxidative stress response -- Catalase A, peroxisomal" YDR269C YDR269C 0.533464379 0.391569201 "YDR269C -- unknown -- unknown function, questionable ORF" YDR271C YDR271C 24 0.493796705 iYDR271C 0.518442116 0.654786862 0.311757512 "YDR271C -- unknown -- unknown function, questionable ORF" YDR274C YDR274C 0.327662902 iYDR274C 0.440126783 0.271920626 0.306606962 YDR274C -- unknown -- unknown function YDR278C YDR278C 0.891694406 itE(CUC)D-0 itE(CUC)D-1 0.613369892 0.19944925 0.80906671 0.973251692 0.596149099 "YDR278C -- unknown -- unknown function, may not be coding because a tRNA-Glu is contained within the ORF" YDR290W YDR290W 44 0.65005965 0.573842514 YDR290W -- unknown -- unknown function YDR314C YDR314C 0.306367254 iYDR314C 0.143650737 0.847947084 0.136015799 YDR314C -- unknown -- unknown function YDR340W YDR340W 0.710061754 iYDR339C 0.644579552 0.392765066 0.610960257 YDR340W -- unknown -- similarity to Hap1p transcription activator YDR344C YDR344C 0.854023403 iYDR344C 0.677694036 0.925753183 0.490602565 YDR344C -- unknown -- unknown function YDR355C YDR355C 0.772216966 0.984366 YDR355C -- unknown -- unknown function YDR360W YDR360W 0.457358116 0.780573026 YDR360W -- unknown -- unknown function YDR366C YDR366C 21 0.878267438 0.978070175 YDR366C -- unknown -- unknown function YDR374C YDR374C 25 0.380708604 iYDR374C 0.481666227 0.857315501 0.519685705 YDR374C -- unknown -- unknown function YDR401W YDR401W 0.330003823 iYDR400W 0.695078517 0.132797271 0.406953295 YDR401W -- unknown -- unknown function YDR402C DIT2 23 0.168480539 iYDR402C 0.305355066 0.282003711 0.209486166 "DIT2 -- sporulation, spore wall biogenesis -- Cytochrome P450 56, second enzyme in the pathway for biosynthesis of dityrosine in the outer layer of spore wall" YDR413C YDR413C 0.451507126 iYDR413C 0.647255554 0.361781076 0.410454908 YDR413C -- unknown -- unknown function YDR431W YDR431W 31 0.88541256 0.822239693 YDR431W -- unknown -- unknown function YDR437W YDR437W 0.780330441 iYDR436W 0.385860838 0.805586592 0.389381244 YDR437W -- unknown -- unknown function YDR442W YDR442W 0.833091125 iYDR441C 0.600396592 0.937430168 0.441601689 YDR442W -- unknown -- unknown function YDR445C YDR445C 22 0.834713401 itK(CUU)D2 YDRWdelta30 0.672939982 0.702830233 0.907841685 0.472929638 0.509881423 YDR445C -- unknown -- unknown function YDR446W ECM11 0.793810942 itK(CUU)D2 YDRWdelta30 0.672939982 0.702830233 0.399613277 0.472929638 0.509881423 ECM11 -- cell wall biogenesis -- Protein possibly involved in cell wall structure or biosynthesis YDR455C YDR455C 0.80065402 0.961972285 YDR455C -- unknown -- unknown function YDR475C YDR475C 19 0.402497363 iYDR475C 0.406063925 0.54069533 0.321890287 "YDR475C -- unknown -- unknown function, may be a pseudogene or may be separated from YDR474C by sequencing errors" YDR509W YDR509W 17 0.690409197 0.240994525 YDR509W -- unknown -- unknown function YDR521W YDR521W 39 0.250590378 0.509018356 YDR521W -- unknown -- unknown functionquestionable ORF YDR522C SPS2 0.352036345 iYDR522C 0.477399525 0.861862116 0.515722267 SPS2 -- meiosis -- middle/late stage of sporulation YDR523C SPS1 0.278055152 iYDR523C 0.479494316 0.598617625 0.454560103 SPS1 -- meiosis -- Serine/threonine protein kinase involved in middle/late stage of meiosis YDR525W YDR525W 0.827914383 iYDR524C 0.856616742 0.788180026 0.653158234 YDR525W -- unknown -- unknown function YDR526C YDR526C 13 0.480216358 0.60125072 YDR526C -- unknown -- unknown function YDR532C YDR532C 19 0.288798709 iYDR532C 0.416809179 0.370525796 0.556254368 YDR532C -- unknown -- unknown function YDR535C YDR535C 0.740165129 iYDR535C 0.41367758 0.858313619 0.728327425 YDR535C -- unknown -- unknown function YDR536W STL1 0.677304917 iYDR535C 0.41367758 0.953092243 0.728327425 STL1 -- transport -- member of hexose transporter family of major facilitator superfamily (MFS) YDR537C YDR537C 0.52726483 0.772067039 YDR537C -- unknown -- unknown functionquestionable ORF YDR540C YDR540C 0.675733578 iYDR540C YDRWdelta31 0.535395443 0.722554692 0.521430873 0.594344183 0.206904896 YDR540C -- unknown -- unknown function YDR544C YDR544C 0.999757164 iYDR544C 0.997659272 0.428411812 0.12959763 YDR544C -- unknown -- unknown function YEL010W YEL010W 0.574643863 iYEL011W itK(CUU)E1 0.815176821 0.689011794 0.829191033 0.688667199 0.551077414 YEL010W -- unknown -- unknown function YEL019C MMS21 0.188840408 iYEL019C 0.117619882 0.308169513 0.069681771 MMS21 -- DNA repair -- DNA repair YEL041W YEL041W 27 0.369920673 iYEL042W 0.390471039 0.654527876 0.196499153 YEL041W -- unknown -- similarity to Fre2p YEL045C YEL045C 29 0.965431305 iYEL045C 0.917222031 0.074282952 0.332196231 "YEL045C -- unknown -- unknown function, has motifs typical of ATP/GTP binding sites" YEL059W YEL059W 0.455502854 0.212712997 YEL059W -- unknown -- unknown function YEL067C YEL067C 13 0.611520878 0.75904695 YEL067C -- unknown -- unknown function YEL069C HXT13 0.316739865 iYEL069C-0 iYEL069C-1 0.575461979 0.703475373 0.715356107 0.458266194 0.616280926 HXT13 -- transport -- Member of hexose transporter family of major facilitator superfamily (MFS) YEL073C YEL073C 0.935634905 iYEL073C-0 iYEL073C-1 0.944282165 0.830189082 0.751976499 0.824282952 0.864806001 YEL073C -- unknown -- unknown function YEL074W YEL074W 0.990626344 iYEL075C 0.982131152 0.035207863 0.505881405 YEL074W -- unknown -- unknown function YER044C-A MEI4 14 0.320565175 iYER044C-A 0.14346372 0.668546568 0.258853151 "MEI4 -- meiosis, chromosome pairing and recombination -- Protein required early in meiosis for meiotic recombination, chromosome synapsis, and viable spore formation" YER054C GIP2 0.420990126 iYER054C 0.223819266 0.558579409 0.185367428 "GIP2 -- glucose repression -- Glc7p-interacting protein, possible regulatory subunit for the PP1 family protein phosphatase Glc7p" YER085C YER085C 16 0.252624516 iYER085C 0.38118724 0.163607342 0.329096828 YER085C -- unknown -- unknown function YER106W YER106W 14 0.269311156 iYER105C 0.723079462 0.635115722 0.261490368 "YER106W -- unknown -- unknown function, putative coiled-coil protein induced in sporulation" YER119C-A YER119C-A 45 0.269326087 0.160893855 YER119C-A -- unknown -- unknown function YER181C YER181C 0.858611508 iYER181C YERCdelta26 0.221191648 0.366181712 0.880454949 0.159039639 0.338626858 YER181C -- unknown -- unknown function YER187W YER187W 14 0.712491064 iYER186C YERComega1 0.393573506 0.709729267 0.7755398 0.605118078 0.385419238 YER187W -- unknown -- Degenerate open reading frame with similarity to KHS killer toxin YFL003C MSH4 0.447892845 iYFL003C itN(GUU)F 0.57735445 0.873806055 0.052028717 0.268090521 "MSH4 -- meiosis, recombination -- Meiosis-specific protein homologous to E. coli MutS" YFL011W HXT10 14 0.414559577 iYFL012W 0.251903973 0.410099218 0.311365653 "HXT10 -- transport -- Hexose transporter, member of hexose transporter family of major facilitator superfamily (MFS)" YFL012W YFL012W 37 0.512233515 iYFL013W-A 0.587902272 0.384267259 0.417966212 YFL012W -- unknown -- unknown function YFL013W-A YFL013W-A 0.210784748 0.145277083 "YFL013W-A -- unknown -- unknown function, questionable ORF" YFL019C YFL019C 15 0.433532705 iYFLWdelta1 itP(UGG)F 0.868209473 0.650326589 0.220091247 0.876855547 0.187690282 YFL019C -- unknown -- unknown function YFL030W YFL030W 11 0.508197912 iYFL031W 0.137756094 0.807789794 0.044042914 YFL030W -- unknown -- Putative alanine glyoxylate aminotransferase (serine pyruvate aminotransferase) YFL032W YFL032W 18 0.403884559 iYFL033C 0.227393724 0.596512683 YFL032W -- unknown -- unknown function YFL040W YFL040W 0.855598647 iYFL041W 0.751776707 0.999274018 0.722290792 "YFL040W -- unknown -- Putative hexose transporter, member of hexose transport family of major facilitator superfamily (MFS)" YFL052W YFL052W 0.549470143 iYFL053W-0 iYFL053W-1 0.271490915 0.155908161 0.710932424 0.365334633 0.478074773 "YFL052W -- unknown -- strong similarity to MAL regulatory proteins, Mal63p, Mal33p, and Mal23p" YFL053W DAK2 20 0.278386629 iYFL054C 0.196952449 0.810760668 0.613993711 DAK2 -- carbohydrate metabolism; stress response -- Dihydroxyacetone kinase YFL061W YFL061W 0.871173378 iYFL062W-0 iYFL062W-1 0.852610665 0.676141939 0.93886672 0.111186212 0.43111505 "YFL061W -- unknown -- Protein strongly induced after DNA alkylation damage, has similarity to Myrothecium verrucaria cyanamide hydratase (nitrile hydratase, urea hydrolyase), identical to Ynl335p" YFL063W YFL063W 0.997638402 iYFL064C 0.996902638 0.059861424 0.103860936 YFL063W -- unknown -- similarity to Gin11p and Ykl225p YFL067W YFL067W 0.855474234 iYFL068W 0.518779343 0.387064922 0.031205108 YFL067W -- unknown -- similarity to periodic clock protein YFL068W YFL068W 0.961631024 0.12345679 "YFL068W -- unknown -- similarity to other subtelomerically-encoded proteinsincluding Yhr219p, Yll066p, and Yhl050p" YFR012W YFR012W 43 0.267281659 iYFR011C itY(GUA)F1 0.708943017 0.77874145 0.240223464 0.252980986 0.690219143 YFR012W -- unknown -- unknown function YFR023W PES4 11 0.643751291 iYFR022W 0.620467168 0.811405985 0.467724801 "PES4 -- DNA replication -- Suppressor of DNA polymerase epsilon mutation (PAB-like protein), contains 4 RNA recognition (RRM) domains" YFR027W YFR027W 13 0.354644519 iYFR026C YFRWdelta10 0.239995996 0.118686747 0.539808018 0.362410656 0.031770185 "YFR027W -- mitosis, sister chromatid cohesion (putative) -- Protein required to establish cohesion between sister chromatids during DNA replication" YFR032C YFR032C 0.978537913 iYFR032C YFR032C-A 0.852388052 0.846748877 0.497605746 0.502262816 0.460380153 YFR032C -- unknown -- weak similarity to S. pombe poly(A)-binding protein (SP YFR046C YFR046C 19 0.184070135 iYFR046C 0.244293346 0.631114605 YFR046C -- unknown -- unknown function YFR054C YFR054C 0.524540683 iYFR054C-0 iYFR054C-1 0.750902412 0.485106039 0.824876986 0.439703154 0.661289022 YFR054C -- unknown -- unknown function YFR056C YFR056C 0.850387278 0.9675728 YFR056C -- unknown -- unknown function YFR057W YFR057W 45 0.996546366 iYFR055W-0 iYFR055W-1 0.529545087 0.863536103 0.963341927 0.104566645 0.347141001 YFR057W -- unknown -- unknown function YGL015C YGL015C 18 0.116295787 iYGL015C 0.10140639 0.522800516 0.247559894 YGL015C -- unknown -- unknown function YGL018C JAC1 0.211184981 iYGL018C 0.239824931 0.52120229 0.161287597 JAC1 -- protein folding -- Homolog of E. coli Hsc20 co-chaperonin YGL024W YGL024W 29 0.304439637 0.14111742 YGL024W -- unknown -- unknown functionquestionable ORF YGL033W HOP2 20 0.636159369 iYGL034C-0 iYGL034C-1 0.224385398 0.293285827 0.81832098 0.124578293 0.478810828 "HOP2 -- meiosis, chromosome pairing (putative) -- pairing of homologous chromosomes in meiosis" YGL034C YGL034C 0.316165155 iYGL034C-0 iYGL034C-1 0.224385398 0.293285827 0.367305833 0.124578293 0.478810828 YGL034C -- unknown -- unknown function YGL046W YGL046W 0.340935383 iYGL047W itV(AAC)G1 0.413557084 0.482794677 0.588125406 0.050111084 0.345094279 YGL046W -- unknown -- unknown function YGL069C YGL069C 0.834709406 0.91458899 YGL069C -- unknown -- unknown functionquestionable ORF YGL089C MFALPHA2 16 0.832822326 iYGL089C 0.704456952 0.81071089 0.556264964 "MFALPHA2 -- mating -- Mating pheromone alpha-factor, processed from a precursor polypeptide to produce two nearly identical mature alpha-factor peptides, one of which is identical to alpha-factor encoded by MFALPHA1" YGL090W LIF1 20 0.627356949 iYGL091C 0.440600717 0.335403727 0.32334308 LIF1 -- DNA replication (putative) -- interacts with DNA ligase protein Dnl4pinvolved in non-homologous DNA end joining YGL109W YGL109W 10 0.254744823 iYGL110C 0.641324719 0.19785575 0.413325805 YGL109W -- unknown -- unknown function YGL118C YGL118C 0.668597454 iYGL118C 0.324778981 0.629369513 0.107929338 YGL118C -- unknown -- similarity to Autographa californica late expression factor eight protein YGL132W YGL132W 0.353674303 iYGL133W 0.56683001 YGL132W -- unknown -- unknown functionquestionable ORF YGL138C YGL138C 17 0.758015505 iYGL138C 0.581727278 0.889327738 0.703990423 YGL138C -- unknown -- Protein possibly involved in sporulation YGL149W YGL149W 0.122203019 0.094623132 YGL149W -- unknown -- unknown function YGL152C YGL152C 0.298850575 iYGL152C 0.515541525 0.1075364 YGL152C -- unknown -- similarity to rat G protein-coupled glutamate receptor YGL165C YGL165C 0.365063947 0.737842508 YGL165C -- unknown -- unknown function YGL170C YGL170C 11 0.660212233 iYGL170C itK(CUU)G2 0.536029752 0.602557876 0.84972067 0.467934257 0.656134288 YGL170C -- unknown -- similarity to phosphoribulokinase precursor YGL177W 0.247574204 IntYGL178W iYGL179C-0 0.284364768 0.413787312 0.740621832 0.306367771 0.850689683 YGL182C YGL182C 18 0.152992365 iYGL182C 0.614027371 0.180730259 0.636468362 YGL182C -- unknown -- unknown functionquestionable ORF YGL183C YGL183C 0.47447544 iYGL183C 0.137738122 0.587535857 0.073018194 YGL183C -- unknown -- unknown function YGL184C STR3 14 0.540125398 iYGL184C 0.24620678 0.899122807 0.428571429 STR3 -- unknown -- strong similarity to cystathionine beta-lyasetranscription induced by the drug FK506 in a GCN4-dependent manner YGL192W IME4 0.745817486 0.90342755 "IME4 -- meiosis -- Positive transcription factor for IME1 and IME2, mediates control of meiosis by carrying signals regarding mating type (a/alpha) and nutritional status" YGL205W POX1 0.56978855 iYGL206C 0.298483591 0.892281663 0.832943454 "POX1 -- fatty acid metabolism -- Acyl-CoA oxidase, first and rate-limiting enzyme of peroxisomal beta-oxidation" YGL217C YGL217C 19 0.480824499 0.627893845 YGL217C -- unknown -- similarity to mouse kinesin-related protein KIF3 YGL218W YGL218W 21 0.602866039 0.832480029 YGL218W -- unknown -- unknown function YGL222C YGL222C 20 0.285318233 iYGL222C 0.10196798 0.394136503 0.129018169 YGL222C -- unknown -- unknown function YGL230C YGL230C 11 0.303104439 iYGL230C 0.258607618 0.764619883 0.226895451 YGL230C -- unknown -- unknown function YGL235W YGL235W 0.642321873 0.850386723 YGL235W -- unknown -- unknown function YGL239C YGL239C 16 0.837520993 0.821151121 YGL239C -- unknown -- unknown function YGL240W DOC1 0.292197775 0.353448276 DOC1 -- cell cycle -- Component of anaphase-promoting complex (APC)required for Clb2p degradation and for the metaphase-anaphase transition YGL259W YPS5 0.7679702 iYGL260W 0.767362797 0.65027933 0.131660169 "YPS5 -- protein degradation -- Yapsin 5, GPI-anchored aspartyl protease" YGL260W YGL260W 0.949716708 iYGL261C 0.911466841 0.775016244 0.448667966 YGL260W -- unknown -- strong similarity to Yir040p and members of Ybl108p/Ycr103p/Ykl223p family YGL262W YGL262W 0.865182089 iYGL263W 0.541734727 0.747969461 0.657316661 YGL262W -- unknown -- unknown function YGR018C YGR018C 0.446962884 iYGR018C 0.681369969 0.398563448 0.624234612 YGR018C -- unknown -- unknown function YGR022C YGR022C 0.19296908 0.417235218 YGR022C -- unknown -- unknown function YGR023W MTL1 0.04941332 0.159925276 "MTL1 -- signaling (putative) -- acts with Mid2p in signal transduction of cell wall stress during pheromone-induced morphorgenesis, has similarity to Mid2p and Kai1p" YGR039W YGR039W 0.415412551 iYGRCdelta16 iYGRCdelta18 0.435648373 0.756610549 0.539372994 0.738748817 0.450495245 YGR039W -- unknown -- unknown function YGR051C YGR051C 0.569900634 iYGR051C 0.659881478 0.680161277 0.488121766 YGR051C -- unknown -- unknown functionquestionable ORF YGR052W YGR052W 23 0.83446657 iYGR051C 0.659881478 0.986273554 0.488121766 YGR052W -- unknown -- Serine/threonine protein kinase of unknown function YGR053C YGR053C 21 0.460016106 iYGR053C 0.483706469 0.829449322 0.750431992 YGR053C -- unknown -- unknown function YGR059W SPR3 14 0.323662578 iYGR058W 0.769505561 0.674186271 0.63471668 SPR3 -- sporulation -- Sporulation-specific septin YGR066C YGR066C 0.605277695 iYGR066C 0.792402928 0.914582629 0.823623304 YGR066C -- unknown -- similarity to Vid24p YGR067C YGR067C 21 0.189319994 iYGR067C 0.271724926 0.675904022 0.509686418 "YGR067C -- unknown -- unknown function, has two tandem zinc finger domains" YGR069W YGR069W YGR069W -- unknown -- unknown function YGR087C PDC6 15 0.400544402 iYGR087C-0 iYGR087C-1 0.603275538 0.020492481 0.680953916 0.643780573 0.234509998 PDC6 -- glycolysis -- Pyruvate decarboxylase isozyme 3 YGR107W YGR107W 17 0.134702796 iYGR106C tL(GAG)G 0.431358265 0.64373521 0.873517787 0.784302654 0.514238295 YGR107W -- unknown -- unknown function YGR115C YGR115C 0.227722209 0.226677149 "YGR115C -- unknown -- unknown function, questionable ORF" YGR139W YGR139W 0.817191647 iYGR138C 0.35767977 0.785552061 0.089814089 YGR139W -- unknown -- unknown function YGR164W YGR164W 0.818145585 0.568927966 YGR164W -- unknown -- similarity to Hansenula wingei mitochondrial site-specific nuclease PIR YGR176W YGR176W 0.895390376 iYGR175C 0.468855649 0.94795539 0.411338764 YGR176W -- unknown -- unknown function YGR190C YGR190C 38 0.431340069 0.690942886 YGR190C -- unknown -- unknown function YGR203W YGR203W 13 0.908760248 iYGR202C 0.71424276 0.946852478 0.771825887 "YGR203W -- unknown -- unknown function, with strong similarity to arsenate reductase Arr2p" YGR213C RTA1 29 0.941158428 iYGR213C 0.96418684 0.89514295 0.395019385 RTA1 -- 7-aminocholesterol resistance -- 7-aminocholesterol resistance YGR221C YGR221C 0.244376371 iYGR221C SNR7-L 0.557391218 0.734869784 0.656903432 0.49597164 0.620776478 YGR221C -- unknown -- unknown function YGR224W AZR1 23 0.346346781 iYGR223C 0.253309916 0.865740741 0.24715657 AZR1 -- unknown -- Member of major facilitator superfamily (MFS) multidrug-resistance (MFS-MDR) protein family YGR225W SPO70 0.177834308 iYGR224W 0.539206275 0.565378721 0.32322336 "SPO70 -- sporulation -- sporulation, has similarity to C. elegans CDC20 protein" YGR226C YGR226C 0.485695075 iYGR226C 0.216694051 0.843432242 0.178639019 YGR226C -- unknown -- unknown function YGR236C YGR236C 0.37725885 iYGR236C 0.280122707 0.631485659 0.165879252 "YGR236C -- unknown -- unknown function, induced during aerobic growth" YGR242W YGR242W 0.565110849 0.783979995 YGR242W -- unknown -- unknown function YGR249W MGA1 15 0.449420076 iYGR248W 0.336354144 0.231147277 0.692388619 MGA1 -- pseudohyphal growth (putative) -- similarity to heat shock transcription factors YGR259C YGR259C 0.869030274 0.596170557 YGR259C -- unknown -- unknown function YGR265W YGR265W 0.60525624 0.789707187 YGR265W -- unknown -- unknown function YGR269W YGR269W 0.233101272 0.125219473 "YGR269W -- unknown -- unknown function, questionable ORF" YGR273C YGR273C 0.535734973 iYGR273C 0.34152508 0.54398091 0.123144453 YGR273C -- unknown -- unknown function YGR290W YGR290W 0.443324036 0.455246914 YGR290W -- unknown -- unknown function YGR291C YGR291C 0.814914704 iYGR291C 0.466488587 0.96231319 0.471727031 YGR291C -- unknown -- unknown function YGR292W MAL12 19 0.626224621 iYGR291C 0.466488587 0.674830809 0.471727031 MAL12 -- maltose utilization -- Alpha-glucosidase (maltase) of MAL1 locus YGR293C YGR293C 15 0.884821899 0.829688747 YGR293C -- unknown -- unknown function YHL005C YHL005C 20 0.822892603 0.973794549 YHL005C -- unknown -- unknown function YHL018W YHL018W 0.054858407 iYHL019C 0.183002194 0.539717349 0.11380534 YHL018W -- unknown -- weak similarity to human pterin-4-alpha-carbinolamine dehydratase YHL022C SPO11 0.875122509 iYHL022C 0.359213665 0.924427973 0.431938029 "SPO11 -- meiosis, recombination -- Catalytic subunit of meiotic double strand break transesterase" YHL028W WSC4 15 0.416780734 iYHL029C 0.08757653 0.473095737 0.056707268 "WSC4 -- cell wall integrity and stress response -- secretory protein translocation, for maintenance of cell wall integrity, and for the stress response" YHL037C YHL037C 16 0.952012029 iYHL037C 0.413917021 0.362662148 0.244494636 YHL037C -- unknown -- unknown function YHL041W YHL041W 29 0.824028199 iYHL042W 0.335245959 0.906854275 0.569242162 YHL041W -- unknown -- unknown function YHL043W ECM34 0.552979732 iYHL044W 0.441317324 0.680555556 0.586439562 ECM34 -- cell wall biogenesis -- Protein possibly involved in cell wall structure or biosynthesis YHR014W SPO13 14 0.815413813 iYHR013C 0.409046184 0.427141112 0.447851153 SPO13 -- meiosis -- Meiosis-specific meiosis I chromosome division YHR015W MIP6 9 0.618311827 iYHR014W itS(AGA)H 0.492037297 0.630591205 0.641526176 0.276364033 0.473665026 "MIP6 -- mRNA export, putative -- similarity to Pes4p and Pab1p in the N-terminal region, has 4 RNA recognition (RRM) domains" YHR079C-A 21 0.793305991 iYHR079C-B 0.576386404 0.587176799 0.411512928 YHR093W AHT1 0.449069106 iYHR092C 0.425806929 0.394493216 0.644254475 "AHT1 -- unknown -- unknown function, probable non-functional ORF upstream of HXT4" YHR095W YHR095W 0.815760167 iYHR094C 0.628592348 0.476616121 0.501995211 YHR095W -- unknown -- unknown function YHR109W CTM1 0.496395443 iYHR108W 0.223668535 0.756584198 0.04985077 CTM1 -- unknown -- Cytochrome c methyltransferase YHR124W NDT80 13 0.533036312 iYHR123W 0.58967401 0.859297686 0.628255991 NDT80 -- meiosis -- Meiosis-specific exit from pachytene YHR125W YHR125W 41 0.615993616 itF(GAA)H2 YHRCdelta8 0.632799998 0.732713911 0.797531661 0.462450593 0.521718353 YHR125W -- unknown -- unknown function YHR126C YHR126C 10 0.661074248 iYHR126C 0.233181345 0.830003223 0.167708685 YHR126C -- unknown -- similarity to members of Pir1p/Hsp150p/Pir3p family YHR139C-A YHR139C-A 0.639735133 iYHR139C-A 0.492957746 0.593022299 0.27384185 YHR139C-A -- unknown -- unknown function YHR140W YHR140W 20 0.702869119 iYHR139C-A 0.492957746 0.847198548 0.27384185 "YHR140W -- unknown -- unknown function, has 6 potential transmembrane segments" YHR145C YHR145C 22 0.820838975 iYHRCdelta10 YHRCdelta11 0.434300107 0.676096339 0.963687151 0.478598651 0.679286296 YHR145C -- unknown -- unknown function YHR153C SPO16 0.394444716 iYHR153C 0.124452672 0.771361274 0.141179453 "SPO16 -- meiosis, spore formation -- Early meiotic efficient spore formation" YHR159W YHR159W 38 0.220908882 iYHR158C 0.133325513 0.66218176 0.172169811 YHR159W -- unknown -- unknown function YHR160C PEX18 17 0.514063141 iYHR160C 0.086624286 0.810971349 0.04632601 PEX18 -- peroxisome biogenesis (putative) -- Peroxisomal biogenesis protein (peroxin) involved with Pex21p in Pex7p-mediated peroxisomal protein targeting YHR177W YHR177W 16 0.239890666 iYHR176W 0.277186528 0.258647799 0.168209877 YHR177W -- unknown -- unknown function YHR180W YHR180W 0.724335218 iYHR179W YHRCdelta12 0.541365759 0.704842175 0.945730247 0.511231795 0.680961663 YHR180W -- unknown -- unknown function YHR185C ADY1 25 0.659948195 iYHR185C itV(CAC)H 0.548397684 0.550940077 0.886193136 0.199510832 0.378746374 ADY1 -- meiosis (putative) -- sporulation YHR189W YHR189W 0.146846775 iYHR188C 0.5206696 0.516894087 0.677408959 YHR189W -- protein synthesis -- Putative peptidyl-tRNA hydrolase YHR210C YHR210C 12 0.840945227 iYHR210C-0 iYHR210C-A 0.580642249 0.736198802 0.951754386 0.885272317 0.664565044 "YHR210C -- unknown -- similarity to Gal10p, has strong similarity to mutarotase proteins" YHR217C YHR217C 25.5 0.998291419 iYHR217C 0.995206987 0.020430966 0.159259885 YHR217C -- unknown -- unknown function YIL006W YIL006W 0.785306751 iYIL007C 0.226800462 0.938308061 0.417103424 "YIL006W -- unknown -- Member of mitochondrial carrier (MCF) family of membrane transporters, has similarity to Flx1p and Yel006p" YIL012W YIL012W 26 0.590647073 iYIL013C 0.225661549 0.664166002 0.175555914 YIL012W -- unknown -- unknown function YIL017C YIL017C 17 0.368180333 iYIL017C 0.308125964 0.240219408 0.740582399 YIL017C -- unknown -- similarity with adenylate cyclase YIL025C YIL025C 0.620101572 0.717068484 YIL025C -- unknown -- unknown function YIL032C YIL032C 0.850840861 iYIL032C 0.389152196 0.609896249 0.152428372 YIL032C -- unknown -- unknown function YIL037C YIL037C 0.447813919 iYIL037C 0.582909831 0.729370009 0.718820496 YIL037C -- unknown -- unknown function YIL057C YIL057C 0.895855107 iYIL057C itS(UGA)I 0.79949363 0.277043817 0.675099761 0.190241093 0.146036387 YIL057C -- unknown -- unknown function YIL058W YIL058W 0.542246805 0.859623138 YIL058W -- unknown -- unknown function YIL060W YIL060W 37 0.644055993 iYIL061C YILCdelta2 0.299517206 0.815455735 0.941580208 0.039026337 0.941347083 YIL060W -- unknown -- unknown function YIL072W HOP1 41 0.437178322 iYIL073C 0.584694544 0.624344599 0.582105378 "HOP1 -- meiosis, synapsis -- Meiosis-specific protein associated with lateral elements of synaptonemal complex, involved in homologous chromosome synapsis and chiasmata formation" YIL086C YIL086C 44 0.589736231 0.811332801 YIL086C -- unknown -- unknown function YIL089W YIL089W 0.675296727 iYIL090W 0.451625005 0.943469786 0.675818037 YIL089W -- unknown -- unknown function YIL100W YIL100W 14 0.598522367 iYIL101C 0.468158769 0.147697023 0.034796488 "YIL100W -- unknown -- unknown function, questionable ORF" YIL102C YIL102C 0.789036432 iYIL102C itT(AGU)I1 0.630677707 0.647309147 0.983403158 0.845305686 0.542803769 YIL102C -- unknown -- unknown function YIL113W YIL113W 32 0.702789613 iYIL114C 0.593536458 0.73554256 0.879723672 YIL113W -- unknown -- Dual-specificity protein phosphatase YIL122W YIL122W 15 0.639115816 iYIL123W 0.376253273 0.378212291 0.142937808 YIL122W -- unknown -- Possible transcription factorpromotes growth in the presence of alpha mating pheromone YIL132C YIL132C 18 0.989779367 iYIL132C 0.886883371 0.62150594 0.405864198 YIL132C -- unknown -- unknown function YIL163C YIL163C 0.677790085 iYIL163C 0.650148962 0.829418723 0.293022181 YIL163C -- unknown -- unknown function YIL170W 16 0.518952425 0.813567438 YIL175W 0.951399773 0.771206489 YIR013C GAT4 0.672245924 iYIR013C 0.746523032 0.781866825 0.634078212 GAT4 -- transcription (putative) -- Putative GATA zinc finger transcription factor YIR017C MET28 0.749027685 iYIR017C 0.663222735 0.621645576 0.300718276 "MET28 -- sulfur amino acid metbolism -- Transcriptional activator regulating sulfur amino acid metabolism that functions with Met4p and Cbf1p, member of basic leucine zipper (bZIP) family" YIR018W YAP5 0.719426287 iYIR017C 0.663222735 0.659935789 0.300718276 "YAP5 -- transcription -- Transcription factor of basic leucine zipper (bZIP) type, one of eight members of a novel fungal-specific family of bZIP proteins" YIR019C MUC1 20 0.586196452 iYIR019C 0.706317003 0.403726708 0.556899531 "MUC1 -- flocculation and invasive growth -- Cell surface flocculin, required for invasive and pseudohyphal growth" YIR027C DAL1 0.094948415 iYIR027C 0.374065439 0.404359581 0.861268823 DAL1 -- allantoin utilization -- Allantoinasefirst step in the degradation of allantoin as a nitrogen source YIR040C YIR040C 0.939486172 iYIR040C 0.894784592 0.767677574 0.37394412 "YIR040C -- unknown -- similarity to Yil174p, Yil175p, and Ycr103p, member of Ybl108p/Ycr103p/Ykl223p family" YJL007C YJL007C 15 0.914926134 itM(CAU)J2 0.810264667 0.924750242 0.705050961 YJL007C -- unknown -- unknown function YJL022W YJL022W 14 0.711485309 0.806142442 "YJL022W -- unknown -- unknown function, overlaps PET130" YJL037W YJL037W 11 0.100457762 iYJL038C 0.162391358 0.272360734 0.484404692 YJL037W -- unknown -- unknown function YJL038C YJL038C 0.234658546 iYJL038C 0.162391358 0.225698324 0.484404692 YJL038C -- unknown -- unknown function YJL043W YJL043W 32 0.677260212 iYJL044C 0.543826389 0.619101395 0.309619723 YJL043W -- unknown -- unknown function YJL056C ZAP1 16 0.4039753 iYJL056C 0.739039973 0.452274541 0.221892746 "ZAP1 -- transport (Zn) -- Zinc-responsive transcriptional activator, regulates genes involved in zinc uptake, has eight C2H2-type zinc fingers" YJL059W YHC3 22 0.309041563 iYJL060W 0.516268996 0.692738791 0.454161968 YHC3 -- unknown -- similarity to human Batten's disease YJL064W YJL064W 0.156937265 0.30766066 YJL064W -- unknown -- unknown function YJL067W YJL067W 24 0.370160917 iYJL068C 0.842210276 0.531875849 0.437340574 YJL067W -- unknown -- unknown function YJL077C ICS3 0.747774599 iYJL077C 0.489889409 0.529563604 0.392619718 "ICS3 -- Cu2+ ion homeostasis (putative) -- normal resistance to copper, has a possible role in signal transduction" YJL086C YJL086C 18 0.782386573 0.933451499 YJL086C -- unknown -- unknown function YJL088W ARG3 16 0.446207352 iYJL089W 0.336039889 0.844426974 0.14022398 "ARG3 -- arginine biosynthesis -- Ornithine carbamyltransferase, catalyzes the sixth step in the arginine biosynthesis pathway" YJL105W YJL105W 42 0.199954547 iYJL106W-0 iYJL106W-1 0.338107433 0.249083822 0.443055086 0.766999678 0.670235421 YJL105W -- unknown -- similarity to Ykr029p YJL144W YJL144W 0.017448288 iYJL145W 0.068746005 0.114951041 0.186620588 YJL144W -- unknown -- unknown function YJL152W YJL152W 14 0.625946854 iYJL153C 0.282827775 0.661894183 0.147947009 YJL152W -- unknown -- unknown function YJL153C INO1 24 0.512652161 iYJL153C 0.282827775 0.945053174 0.147947009 "INO1 -- inositol biosynthesis -- Inositol-1-phosphate synthase (L-myo-inositol-1-phosphate synthase), functions in the inositol biosynthesis pathway" YJL161W YJL161W 0.655592149 iYJL162C itE(UUC)J 0.573567427 0.390702899 0.734014675 0.618790132 0.407145353 YJL161W -- unknown -- unknown function YJL175W YJL175W 19 0.044134637 0.174940144 YJL175W -- unknown -- unknown function YJL182C YJL182C 0.686797504 0.767033543 YJL182C -- unknown -- unknown functionquestionable ORF YJL195C YJL195C 0.528492796 0.641855357 "YJL195C -- unknown -- unknown function, questionable ORF" YJL211C YJL211C 0.233700458 0.602580995 YJL211C -- unknown -- unknown function YJL215C YJL215C 0.631075171 iYJL215C 0.694107172 0.828272854 0.394516931 YJL215C -- unknown -- unknown function YJL216C YJL216C 0.407736048 iYJL216C 0.577668429 0.767443736 0.548681133 YJL216C -- unknown -- similarity to Mal62p (glucosidase P1) YJL219W HXT9 13 0.484358225 iYJL220W 0.38866062 0.94769014 0.61297088 "HXT9 -- transport -- Hexose transporter, member of hexose transporter family of major facilitator superfamily (MFS)" YJL220W YJL220W 16 0.189168914 0.38482781 YJL220W -- unknown -- similarity to alpha-D-glucosidase YJR018W YJR018W 0.300103592 0.48814165 YJR018W -- unknown -- unknown function YJR020W YJR020W 73 0.43792843 0.81469596 YJR020W -- unknown -- unknown function YJR023C YJR023C 0.385578438 0.483839972 YJR023C -- unknown -- weak similarity to sodium channel proteins YJR037W YJR037W 13 0.017699115 0.068954509 YJR037W -- unknown -- unknown function YJR038C YJR038C 0.084740819 0.064839957 "YJR038C -- unknown -- unknown function, questionable ORF" YJR061W YJR061W 14 0.631125794 iYJR060W 0.268586517 0.841580208 0.267957781 YJR061W -- unknown -- unknown function YJR071W YJR071W 15 0.713895807 0.917976939 YJR071W -- unknown -- unknown function YJR094C IME1 0.467635189 iYJR094C-0 iYJR094C-1 0.736135422 0.967842065 0.304769392 0.587077519 0.378826942 "IME1 -- meiosis -- Transcription factor required for sporulation, positive regulator of IME2 and many sporulation genes" YJR108W ABM1 22 0.441544016 iYJR107W 0.461400938 0.592857731 0.559732193 ABM1 -- cytoskeleton (putative) -- normal microtubule structure YJR120W YJR120W 0.73781695 iYJR119C 0.433232257 0.544634225 0.483080889 "YJR120W -- unknown -- respiratory growth, also has a role in stress resistance and mating" YJR128W YJR128W 0.132097193 0.37274747 YJR128W -- unknown -- unknown function YJR150C DAN1 0.394071266 iYJR150C-0 iYJR150C-1 0.318776403 0.628727795 0.607417568 0.514213775 0.61943553 "DAN1 -- unknown -- Cell wall mannoprotein induced during anaerobic growth, member of seripauperin (PAU) family of possible cell wall mannoproteins" YJR157W YJR157W 0.668919039 iYJR156C 0.411945666 0.852222312 0.637031125 YJR157W -- unknown -- unknown function YJR158W HXT16 37 0.333860364 iYJR157W-0 iYJR157W-1 0.288285039 0.400960398 0.363291892 0.607762625 0.59788914 HXT16 -- transport -- Member of hexose transporter family of major facilitator superfamily [MFS] YKL030W YKL030W 0.740453851 0.348603352 YKL030W -- unknown -- unknown functionquestionable ORF YKL036C YKL036C 0.377147661 0.701390603 YKL036C -- unknown -- unknown functionquestionable ORF YKL037W YKL037W 16 0.312289829 iYKL038W 0.540191677 0.367353836 0.763367917 YKL037W -- unknown -- unknown function YKL050C YKL050C 27 0.125426819 iYKL050C 0.407628438 0.5203835 0.464789869 "YKL050C -- unknown -- unknown function, has significant similarity to Ymr031p" YKL053W YKL053W 14 0.479660131 iYKL053C-A YKL053C-A 0.422374104 0.487910611 0.58524009 0.288986355 0.670550678 YKL053W -- unknown -- unknown functionquestionable ORF YKL070W YKL070W 0.406001133 iYKL071W 0.601720829 0.859457302 0.500675904 YKL070W -- unknown -- similarity to Bacillus subtilis transcriptional regulatory protein 2 YKL097C YKL097C 0.963028089 iYKL097C 0.80700764 0.854561587 0.361309965 YKL097C -- unknown -- unknown function YKL102C YKL102C 0.608758735 iYKL102C 0.395260608 0.888751749 0.455607477 YKL102C -- unknown -- unknown function YKL107W YKL107W 0.46693938 iYKL108W 0.246118071 0.882066277 0.472533091 YKL107W -- unknown -- unknown function YKL118W YKL118W 19 0.82144867 0.777094972 YKL118W -- unknown -- unknown functionquestionable ORF YKL131W YKL131W 0.309522475 0.539584996 YKL131W -- unknown -- unknown functionquestionable ORF YKL147C YKL147C 16 0.467253101 0.429467072 "YKL147C -- unknown -- unknown function, highly questionable ORF" YKL171W YKL171W 0.472004474 iYKL172W 0.071876518 0.400726597 0.050946266 YKL171W -- unknown -- Serine/threonine protein kinase of unknown function YKL177W YKL177W 17 0.903044806 0.821196412 YKL177W -- unknown -- unknown functionquestionable ORF YKL188C PXA2 16 0.267750269 iYKL188C 0.42039007 0.711135519 0.689246264 "PXA2 -- transport -- long-chain fatty acid transport across the peroxisomal membrane, member of ATP-binding cassette (ABC) superfamily, has similarity to a human gene associated with adrenoleukodystrophy" YKL202W YKL202W 40 0.228595689 iYKL203C 0.233027596 0.160812117 0.269566737 YKL202W -- unknown -- unknown functionquestionable ORF YKL221W YKL221W 0.340634542 iYKL222C 0.570414504 0.652992817 0.393081761 "YKL221W -- unknown -- similarity to mammalian monocarboxylate transporters MCT1 and MCT2, member of monocarboxylate porter (MCP) family of major facilitator superfamily (MFS)" YKL223W YKL223W 0.934531266 iYKL224C 0.94036254 0.820351157 0.538905133 "YKL223W -- unknown -- unknown function, has similarity to other subtelomerically encoded proteins" YKR009C FOX2 0.495643682 iYKR009C iYKRCdelta8 0.289107365 0.605050404 0.786255237 0.33822699 0.254711155 "FOX2 -- fatty acid metabolism -- 3-hydroxyacyl-CoA epimerase (hydratase-dehydrogenase-epimerase), second trifunctional enzyme of fatty acid beta-oxidation pathway" YKR012C YKR012C 0.48103353 0.912849162 YKR012C -- unknown -- unknown functionquestionable ORF YKR015C YKR015C 0.101748365 iYKR015C 0.300065338 0.068308875 0.341211583 YKR015C -- unknown -- unknown function YKR032W YKR032W 0.139996729 iYKR031C 0.003858833 0.084277733 0.003373653 YKR032W -- unknown -- unknown function YKR033C YKR033C 11 0.055225365 0.153871472 YKR033C -- unknown -- unknown functionquestionable ORF YKR034W DAL80 0.143574827 0.155214425 DAL80 -- nitrogen catabolism -- GATA-type zinc finger transcriptional repressor for allantoin and 4-aminobutyric acid (GABA) catabolic genes YKR041W YKR041W 0.358867198 0.603143257 YKR041W -- unknown -- unknown function YKR105C YKR105C 19 0.967915365 iYKR105C 0.939092153 0.491027152 0.323623797 YKR105C -- unknown -- Member of multidrug-resistance 14-spanner family of major facilitator superfamily (MFS-MDR) YLL005C YLL005C 18 0.646049464 iYLL005C 0.274780931 0.677813248 0.42514363 YLL005C -- unknown -- unknown function YLL013C YLL013C 19 0.307469246 iYLL013C 0.224673608 0.212370311 0.171763966 YLL013C -- unknown -- similarity to Drosophila pumilio protein YLL017W SDC25 0.178442939 iYLL018C 0.370187354 0.422428373 0.725541353 "SDC25 -- unknown -- GDP/GTP exchange factor for Ras, has an SH3 domain" YLL030C YLL030C 0.826533916 iYLL030C 0.292979564 0.831211731 0.412672241 YLL030C -- unknown -- similarity to Ca2+-transporting ATPase YLL037W YLL037W 28 0.762687272 0.841130604 YLL037W -- unknown -- weak similarity to human platelet-activating factor receptor YLL046C RNP1 18 0.603872259 iYLL046C 0.802523132 0.536081626 0.699498066 "RNP1 -- unknown -- Ribonucleoprotein 1, contains two RNA recognition (RRM) domains which include RNP-1 octamer and RNP-2 hexamer motifs" YLL047W YLL047W 17 0.119932219 iYLL048C 0.633126429 0.210167715 0.293680297 YLL047W -- unknown -- unknown function YLL054C YLL054C 23 0.401559611 iYLL054C 0.628242047 0.733836907 0.344523986 "YLL054C -- unknown -- similarity to transcription factors, has Zn[2]-Cys[6] fungal-type binuclear cluster domain in the N-terminal region" YLL057C YLL057C 29 0.533045092 iYLL057C 0.58513812 0.707057686 0.655252981 YLL057C -- unknown -- similarity to C-terminal half E. coli dioxygenase YLL059C YLL059C 0.527240111 iYLL059C 0.528945398 0.500766314 0.551738142 YLL059C -- unknown -- unknown function YLL065W GIN11 0.999153668 iYLL066C-0 iYLL066C-1 0.983384079 0.997405681 0.045331205 0.843510527 0.029375463 "GIN11 -- unknown -- similarity to other subtelomerically-encoded proteins including Yjr162p, Ykl225p, and Yfl063p" YLR012C YLR012C 16 0.35492976 iYLR012C 0.18193134 0.520942826 0.220562544 YLR012C -- unknown -- unknown function YLR013W GAT3 0.342780137 iYLR012C 0.18193134 0.379223522 0.220562544 GAT3 -- transcription (putative) -- Putative GATA zinc finger transcription factor YLR030W YLR030W 32 0.653932201 iYLR029C 0.885812264 0.33338711 0.422169811 YLR030W -- unknown -- unknown function YLR031W YLR031W 16 0.485081398 iYLR030W 0.355373734 0.66419814 0.221424538 YLR031W -- unknown -- unknown function YLR035C MLH2 0.289722802 iYLR035C itA(UGC)L 0.149110339 0.438965938 0.65758943 0.170834741 0.296733054 MLH2 -- unknown -- Mismatch repair protein and homolog of E. coli MutL YLR041W YLR041W 43 0.473479962 0.416999202 YLR041W -- unknown -- unknown function YLR053C YLR053C 0.701020162 iYLR053C 0.547955213 0.721491228 0.379165638 YLR053C -- unknown -- similarity to xylose isomerase YLR124W YLR124W 14 0.468200916 iYLR123C 0.61148272 0.818469786 0.78869415 YLR124W -- unknown -- unknown function YLR125W YLR125W 0.153002197 iYLR124W-0 iYLR124W-1 0.558065787 0.417206439 0.402678067 0.646527386 0.891395424 YLR125W -- unknown -- unknown function YLR140W YLR140W 0.3232843 0.102664068 YLR140W -- unknown -- unknown function YLR141W RRN5 0.750939492 0.568201984 "RRN5 -- transcription -- Component of Upstream Activation Factor (UAF) complex, involved in activation of RNA polymerase I" YLR162W YLR162W 0.173032903 iYLR161W 0.023283113 0.368075761 0.004854768 YLR162W -- unknown -- unknown function YLR169W YLR169W 15 0.515482224 iYLR168C 0.641054126 0.292191229 0.368375842 YLR169W -- unknown -- unknown function YLR174W IDP2 0.455975997 iYLR173W 0.454573253 0.789944134 0.381165204 "IDP2 -- TCA cycle -- Isocitrate dehydrogenase (NADP+), cytosolic" YLR184W YLR184W 10 0.977057501 iYLR183C 0.949892415 0.838467678 0.685308355 YLR184W -- unknown -- unknown function YLR232W YLR232W 14 0.549805245 0.797978241 YLR232W -- unknown -- unknown function YLR235C 0.638333824 0.851756365 YLR236C 0.202050896 iYLR236C 0.303846762 0.349442379 0.180284703 YLR267W BOP2 0.36120259 iYLR266C 0.451181063 0.721867518 0.803685291 BOP2 -- unknown -- unknown function YLR279W YLR279W 18 0.372576278 iYLR278C 0.581149283 0.549084456 0.238060429 YLR279W -- unknown -- unknown function YLR280C YLR280C 0.43785407 0.491247883 YLR280C -- unknown -- unknown function YLR281C YLR281C 0.356766826 iYLR281C 0.522289452 0.6528332 0.603673029 YLR281C -- unknown -- unknown function YLR282C YLR282C 0.696586877 0.966685488 YLR282C -- unknown -- unknown function YLR296W YLR296W 43 0.685007512 iYLR295C 0.419459284 0.743379763 0.753229655 YLR296W -- unknown -- unknown function YLR302C YLR302C 0.814805748 0.648529909 YLR302C -- unknown -- unknown function YLR307W CDA1 0.5133123 iYLR306W 0.678335872 0.751013856 0.536076377 "CDA1 -- sporulation -- Chitin deacetylase, responsible along with Cda2p for the synthesis of chitosan for the ascospore wall" YLR308W CDA2 27 0.246928899 iYLR307W 0.454553681 0.333415618 0.615074467 "CDA2 -- sporulation -- Chitin deacetylase, responsible along with Cda1p for the synthesis of chitosan for the ascospore wall" YLR311C YLR311C 50 0.550509738 0.393973574 YLR311C -- unknown -- unknown function YLR312C YLR312C 0.201807232 iYLR312C 0.744579128 0.269574399 0.485953711 YLR312C -- unknown -- unknown function YLR315W YLR315W 0.603179194 iYLR314C 0.543653259 0.790175265 0.495926434 YLR315W -- unknown -- unknown function YLR322W YLR322W 14 0.438405264 0.460030653 YLR322W -- unknown -- unknown function YLR331C YLR331C 0.155643556 0.134548681 YLR331C -- unknown -- unknown function YLR337C VRP1 0.088850642 0.133447044 "VRP1 -- cytoskeleton -- Proline-rich protein verprolin, involved in cytoskeletal organization and cellular growth" YLR338W YLR338W 30 0.230628023 YLR337C 0.088850642 0.033078252 0.133447044 YLR338W -- unknown -- unknown function YLR341W YLR341W 37 0.734638256 iYLR340W 0.707878465 0.744089952 0.787609906 YLR341W -- unknown -- unknown function YLR343W YLR343W 0.794112338 iYLR342W 0.573675765 0.860324042 0.498642311 YLR343W -- unknown -- strong similarity to Gas1p YLR366W YLR366W 0.700538074 0.764096189 "YLR366W -- unknown -- unknown function, possible pseudogene" YLR374C YLR374C 0.426980732 0.45802075 YLR374C -- unknown -- unknown function YLR377C FBP1 0.516880689 iYLR377C itK(UUU)L 0.461880158 0.780953937 0.774895263 0.48106671 0.669597483 "FBP1 -- gluconeogenesis -- Fructose-1,6-bisphosphatasegluconeogenic enzyme inhibited by protein kinase A-mediated phosphorylation" YLR379W YLR379W 0.264194324 0.606568833 YLR379W -- unknown -- unknown function YLR385C YLR385C 0.635180883 iYLR385C 0.209421979 0.836431227 0.374010776 YLR385C -- unknown -- unknown function YLR393W ATP10 0.700714417 iYLR392C 0.816586532 0.672946942 0.780615533 ATP10 -- ATP synthesis -- F1-F0 ATP synthase assembly YLR415C YLR415C 22 0.273940712 0.185103964 YLR415C -- unknown -- unknown functionquestionable ORF YLR416C YLR416C 11 0.391334873 iYLR416C 0.248525178 0.201419698 0.174074373 YLR416C -- unknown -- unknown function YLR428C YLR428C 16 0.543371654 YLR428C -- unknown -- unknown function YLR445W YLR445W 0.289882044 iYLR444C 0.576839399 0.342091923 0.493527437 YLR445W -- unknown -- unknown function YLR446W YLR446W 0.51338087 iYLR445W 0.451697601 0.573113208 0.343242365 YLR446W -- unknown -- similarity to human hexokinase I YLR458W 0.172812977 0.099756071 YLR463C YLR463C 0.962204835 0.904527876 YLR463C -- unknown -- unknown function with similarity to other subtelomerically-coded proteins YML003W YML003W 0.734837852 iYML004C 0.183732396 0.609976057 0.1836932 YML003W -- unknown -- unknown function YML013C-A 0.61636877 iYML013C-A 0.276714442 0.50164207 0.13782921 YML032C-A 16 YML035C-A 22 0.399554832 0.420484081 YML047C YML047C 0.201236896 iYML047C 0.389429252 0.719948018 0.327516299 YML047C -- unknown -- unknown function YML048W-A 24 0.782287524 iYML048W 0.099967331 0.413631969 0.058301253 YML058C-A 22 0.227668348 0.077941388 YML066C YML066C 49 0.760792944 iYML066C 0.52794502 0.70920384 0.407232704 YML066C -- unknown -- unknown function YML083C YML083C 15 0.323516803 iYML083C 0.722986022 0.239529334 0.848775379 "YML083C -- unknown -- unknown function, induced during anaerobic growth" YML087C YML087C 0.782425151 iYML087C 0.741138774 0.826104613 0.902050296 YML087C -- unknown -- unknown function YML089C YML089C 25 0.860406449 iYML089C 0.961832185 0.393883069 0.887749783 YML089C -- unknown -- unknown function YML090W YML090W 17 0.729258878 0.331131163 YML090W -- unknown -- unknown function YML095C-A YML095C-A 16 0.567508499 "YML095C-A -- unknown -- unknown function, questionable ORF" YML100W-A 0.753387343 iYML100W 0.810528166 0.496113552 0.633943696 YML102C-A 0.715893561 0.599341641 YML122C YML122C 0.349078518 iYML122C 0.463110053 0.718337093 0.291814373 "YML122C -- unknown -- unknown function, questionable ORF" YMR017W SPO20 44 0.309373835 iYMR016C-0 iYMR016C-1 0.212346786 0.281134473 0.270391061 0.357154367 0.435941743 SPO20 -- sporulation -- DBF2-interacting protein YMR031W-A 0.665326795 0.491883682 YMR052C-A 0.674837622 0.367152144 YMR057C YMR057C 0.300716401 iYMR057C 0.618276262 0.674276035 0.266799681 "YMR057C -- unknown -- unknown function, questionable ORF" YMR063W RIM9 0.341563117 iYMR062C 0.336338519 0.918754988 0.609813084 RIM9 -- sporulation -- Sporulation stimulates expression of IME1 YMR068W YMR068W 0.293799971 iYMR067C 0.473282092 0.821973058 0.491298743 YMR068W -- unknown -- similarity to mouse I kappa B gamma and p70 YMR069W YMR069W 15 0.844943885 iYMR068W 0.779434604 0.921513269 0.685028726 YMR069W -- unknown -- unknown function YMR075C-A 0.427365544 iYMR075C-A 0.268440636 0.244987068 0.143179802 YMR081C ISF1 14 0.139096275 iYMR081C 0.406502997 0.272067039 0.214018843 "ISF1 -- RNA splicing, mitochondrial -- participates with Nam7p/Upf1p in suppression of mitochondrial splicing defect" YMR082C YMR082C 0.412738173 iYMR082C-0 iYMR082C-1 0.899019639 0.922161626 0.506735501 0.50052432 0.474231159 YMR082C -- unknown -- unknown function YMR086C-A 0.831931148 iYMR086C-A 0.875446284 0.281905702 0.068555467 YMR095C SNO1 0.468682862 iYMR095C 0.483400674 0.802368675 0.297606569 "SNO1 -- unknown -- Putative pyridoxine (vitamin B6) biosynthetic enzyme with similarity to glutamine aminotransferases, has strong similarity to Sno1p and Sno3p" YMR101C YMR101C 0.851765084 iYMR101C 0.531217521 0.911107526 0.788174139 YMR101C -- protein glycosylation -- Suppressor of rer2has similarity to Rer2p YMR107W YMR107W 0.322292789 iYMR106C itK(CUU)M 0.685331448 0.229834575 0.684224319 0.710441508 0.453416149 "YMR107W -- unknown -- unknown function, induced during aerobic growth" YMR118C YMR118C 33 0.654634617 iYMR118C YMRWdelta16 0.595212409 0.764073371 0.526057183 0.750100831 0.861111111 "YMR118C -- unknown -- Putative succinate dehydrogenase, has similarity to Sdh3p" YMR122C YMR122C 12 0.414630186 iYMR122C-0 iYMR122C-1 0.377522607 0.033755916 0.625971612 0.221787709 0.177650661 "YMR122C -- unknown -- unknown function, questionable ORF" YMR133W REC114 41 0.250829981 iYMR132C 0.706884635 0.284925276 0.733509347 "REC114 -- meiosis, recombination -- Meiotic recombination protein, mutants are defective in double-strand break formation" YMR135W-A 0.347739977 0.150557621 YMR147W YMR147W 0.326019456 iYMR146C 0.142160826 0.379538404 0.087470072 YMR147W -- unknown -- unknown function YMR151W YIM2 17 0.187246632 0.708570468 YIM2 -- unknown -- unknown function YMR158W-A 0.665377414 YMR158C-B iYMR158C-B 0.680880871 0.245518128 0.564203354 0.886561392 0.634557063 YMR172C-A 40 0.478088855 iYMR172C-A 0.266441126 0.084065563 0.158739026 YMR175W SIP18 33 0.325354056 iYMR174C 0.117453171 0.382075472 0.146383609 SIP18 -- unknown -- induced by osmotic stress YMR182C RGM1 0.024607415 iYMR182C-0 iYMR182C-1 0.216265623 0.556553484 0.153343551 0.601835595 "RGM1 -- transcription -- Transcriptional repressor homologous to mammalian EGR (early growth response) factor, has two tandem C2H2-type zinc fingers" YMR190C SGS1 25 0.463305219 iYMR190C 0.250838832 0.359161793 0.188916673 "SGS1 -- mitosis, chromosome segregation -- DNA helicase of DEAD/DEAH family, has similarity to the human Werner's and Bloom's syndromes genes and to E. coli RecQ 3'-5' DNA helicase" YMR193C-A 27 0.932793509 0.228488559 YMR206W YMR206W 0.456468474 iYMR205C 0.796796572 0.376572327 0.418937806 YMR206W -- unknown -- unknown function YMR244W YMR244W 17 0.867977192 iYMR243C 0.970519638 0.865049952 0.646629858 YMR244W -- unknown -- similarity to Nca3p YMR251W YMR251W 0.703809556 iYMR250W 0.621988137 0.585706219 0.123106671 YMR251W -- unknown -- Putative paralog of Ecm4p YMR254C YMR254C 17 0.532084275 iYMR254C 0.474592522 0.645572829 0.189999866 "YMR254C -- unknown -- unknown function, questionable ORF" YMR279C YMR279C 0.122556742 iYMR279C 0.336403853 0.474862174 0.791831409 YMR279C -- unknown -- Member of multidrug-resistance 14-spanner family of major facilitator superfamily (MFS-MDR) YMR280C CAT8 15 0.36997323 iYMR280C 0.578205364 0.457940942 0.893867925 CAT8 -- gluconeogenesis -- Transcription factor required for derepression of gluconeogenic enzymeshas a Zn[2]-Cys[6] fungal-type binuclear cluster domain in the N-terminal region YMR294W-A 0.715132991 iYMR294W 0.495417241 0.296634576 0.135703645 YMR306C-A 0.541934045 iYMR306C-A 0.089535669 0.342767296 0.147987822 YMR306W FKS3 0.323992572 iYMR305C 0.599325234 0.279489226 0.824349442 FKS3 -- unknown -- similarity to Fks1p and Gsc2p YMR317W YMR317W 0.179128929 0.359974009 YMR317W -- unknown -- unknown function YMR322C YMR322C 16 0.65604321 iYMR322C 0.755106709 0.427634756 0.301981806 YMR322C -- unknown -- unknown function YMR323W YMR323W 12 0.898265879 iYMR322C 0.755106709 0.361372706 0.301981806 YMR323W -- unknown -- similarity to enolases YMR324C YMR324C 0.810528296 iYMR324C 0.921821347 0.318581262 0.298802873 YMR324C -- unknown -- similarity to members of Ybl108p/Ycr103p/Ykl223p family YMR326C YMR326C 0.997334711 0.047964884 YMR326C -- unknown -- similarity to members of PAU1 family YNL017C YNL017C 0.33378889 itI(AAU)N2 0.128118783 YNL017C -- unknown -- unknown function YNL018C YNL018C 0.178524772 iYNL018C 0.127298207 0.254431196 0.12150594 "YNL018C -- unknown -- unknown function, nearly identical to Ynl034p" YNL019C YNL019C 17 0.208654705 iYNL019C 0.183659716 0.450136589 0.201841838 YNL019C -- unknown -- unknown function YNL028W YNL028W 29 0.760047429 0.773403177 "YNL028W -- unknown -- unknown function, questionable ORF" YNL034W YNL034W 16 0.160061098 iYNL035C itI(AAU)N1 0.34094979 0.026225481 0.189919887 0.132477188 0.033242821 "YNL034W -- unknown -- unknown function, nearly identical to Ynl018p" YNL089C YNL089C 0.525117866 iYNL089C 0.302978792 0.478719948 0.288134226 "YNL089C -- unknown -- unknown function, questionable ORF" YNL092W YNL092W 19 0.819285253 iYNL093W 0.247574869 0.983755686 0.292976939 YNL092W -- unknown -- Putative methyltransferase unknown role YNL105W YNL105W 0.299318263 0.720398256 "YNL105W -- unknown -- unknown function, questionable ORF" YNL109W YNL109W 19 0.31374098 iYNL110C 0.248269586 0.307302586 0.14574762 YNL109W -- unknown -- unknown function YNL117W MLS1 18 0.298631279 iYNL118C 0.294260326 0.776155521 0.445617145 "MLS1 -- glyoxylate cycle -- Malate synthase 1, functions in glyoxylate cycle, has near identity to Dal7p" YNL120C YNL120C 0.418450283 0.863288109 "YNL120C -- unknown -- unknown function, questionable ORF" YNL128W TEP1 24 0.050671285 iYNL129W 0.031406832 0.265531145 0.005162539 "TEP1 -- unknown -- Protein tyrosine phosphatase (PTPase), has similarity to human tumor suppressor gene TEP1/MMAC/PTEN1" YNL139C RLR1 18 0.31640587 iYNL139C 0.331354701 0.692344922 0.727924589 RLR1 -- transcription -- transcription and transcription-associated recombinationhas pleiotropic regulatory properties YNL194C YNL194C 0.319448037 iYNL194C 0.65893599 0.696342249 0.805188527 YNL194C -- unknown -- similarity to Sur7p YNL196C SLZ1 0.210095483 iYNL196C 0.704916694 0.182127883 0.691520468 SLZ1 -- meiosis -- Sporulation-specific protein YNL205C YNL205C 0.665016992 0.525458899 YNL205C -- unknown -- unknown function YNL226W YNL226W 0.650889015 0.70280956 YNL226W -- unknown -- unknown functionquestionable ORF YNL228W YNL228W 52 0.198709572 iYNL229C 0.23403912 0.327090008 0.293103448 "YNL228W -- unknown -- unknown function, questionable ORF" YNL235C YNL235C 52 0.331651389 iYNL235C 0.310167388 0.433521661 0.231167661 "YNL235C -- unknown -- unknown function, questionable ORF" YNL269W YNL269W 0.18338644 0.156973461 YNL269W -- unknown -- unknown function YNL270C ALP1 0.324151569 0.445751358 ALP1 -- transport -- strong similarity to permeases Can1p and Lyp1p for basic amino acids YNL276C YNL276C 0.474791649 iYNL276C 0.487849138 0.868186583 0.252969951 "YNL276C -- unknown -- unknown function, questionable ORF" YNL285W YNL285W 27 0.77874932 iYNL286W itG(UCC)N 0.522979404 0.517047286 0.763132452 0.062459389 0.425531738 YNL285W -- unknown -- unknown function YNL296W YNL296W 0.673612524 0.887102014 "YNL296W -- unknown -- unknown function, questionable ORF" YNL318C HXT14 0.47028878 iYNL318C 0.112218229 0.50402836 0.096491228 HXT14 -- transport -- Member of hexose transporter family of major facilitator superfamily [MFS] YNL319W YNL319W 0.363066172 iYNL320W 0.502508398 0.493211553 0.090799227 "YNL319W -- unknown -- unknown function, questionable ORF" YNL324W YNL324W 0.866887963 0.476456504 YNL324W -- unknown -- unknown function YNL335W YNL335W iYNL336W-0 iYNL336W-1 0.913134334 0.663586609 0.358524009 0.640074212 "YNL335W -- unknown -- induced after DNA alkylation damage, has similarity to Myrothecium verrucaria cyanamide hydratase (nitrile hydratase, urea hydrolyase), identical to Yfl061p" YNR005C YNR005C 0.75123792 0.932484692 "YNR005C -- unknown -- unknown function, questionable ORF" YNR025C YNR025C 18 0.280562549 iYNR025C 0.652677495 0.354898485 0.451432565 "YNR025C -- unknown -- unknown function, questionable ORF" YNR042W YNR042W 13 0.171557199 0.255998648 YNR042W -- unknown -- unknown function YNR056C BIO5 18 0.130405191 0.343161144 "BIO5 -- biotin biosynthesis -- Transmembrane regulator of KAPA/DAPA transport, involved in biotin biosynthesis" YNR060W FRE4 11 0.62731212 iYNR059W 0.277733643 0.927875244 0.549493952 "FRE4 -- unknown -- similarity to ferric reductases Fre1p and Fre2p, subject to regulation by iron" YNR062C YNR062C 0.386804821 iYNR062C-0 iYNR062C-1 0.397830819 0.483512655 0.591705752 YNR062C -- unknown -- weak similarity to Haemophilus influenzae L-lactate permease (lctP) homolog YNR063W YNR063W 26 0.371767994 iYNR062C-0 iYNR062C-1 0.397830819 0.629929757 0.591705752 "YNR063W -- unknown -- similarity to transcription factors, has Zn[2]-Cys[6] fungal-type binuclear cluster domain in the N-terminal region" YNR064C YNR064C 30 0.14289056 iYNR064C 0.021165568 0.37571717 0.068794892 "YNR064C -- unknown -- similarity to haloalkane dehalogenase, induced by methylmethanesulfonate (MMS) treatment" YNR066C YNR066C 0.422401888 iYNR066C 0.45023192 0.634364662 0.630921689 YNR066C -- unknown -- similarity to Pep1p YNR072W HXT17 14 0.846188126 iYNR071C 0.33966574 0.971897336 0.356903432 "HXT17 -- transport -- Putative hexose transporter, member of hexose transporter family of major facilitator superfamily (MFS)" YOL024W YOL024W 23 0.576007771 iYOL025W 0.127246236 0.880255237 0.307283274 YOL024W -- unknown -- unknown function YOL035C YOL035C 20 0.598895269 iYOL035C SNR50 0.594941747 0.867863443 0.750324886 0.445580014 0.418291098 YOL035C -- unknown -- unknown function YOL037C YOL037C 0.338131873 0.345841455 YOL037C -- unknown -- unknown function YOL046C YOL046C 0.241902894 0.462649641 YOL046C -- unknown -- unknown function YOL047C YOL047C 17 0.148647401 iYOL047C 0.38195999 0.608699122 0.605782669 YOL047C -- unknown -- unknown function YOL050C YOL050C 0.678066971 iYOL050C 0.089338728 0.777972865 0.131659999 YOL050C -- unknown -- unknown function YOL069W NUF2 0.393542216 iYOL070C 0.545533763 0.360054786 0.321947326 "NUF2 -- cytoskeleton -- Coiled-coil spindle pole body, required for nuclear division" YOL079W YOL079W 0.499187485 0.588946181 YOL079W -- unknown -- similarity to NADH dehydrogenase chain 4 from honeybee mitochondrion YOL084W YOL084W 0.549800525 iYOL085C 0.566707674 0.490167037 0.268774704 YOL084W -- unknown -- unknown function YOL085C YOL085C 50 0.718921696 iYOL085C 0.566707674 0.398727038 0.268774704 YOL085C -- unknown -- unknown function YOL091W SPO21 0.35010742 iYOL092W 0.832979418 0.543276599 0.256732202 SPO21 -- sporulation -- sporulation YOL099C YOL099C 14 0.19762864 iYOL099C 0.386242898 0.362829717 0.157940942 YOL099C -- unknown -- unknown function YOL118C YOL118C 0.897672445 iYOL118C 0.671356218 0.910812117 0.728873529 YOL118C -- unknown -- unknown function YOL131W YOL131W 58 0.342360025 iYOL132W 0.364486868 0.570737995 0.298488195 YOL131W -- unknown -- unknown function YOL132W YOL132W 10 0.388101378 iYOL133W 0.716854607 0.607182761 0.865326124 YOL132W -- unknown -- similarity to glycophospholipid-anchored surface glycoprotein GAS1 YOL156W HXT11 11 0.348470131 iYOL157C 0.228508985 0.6983676 0.291666667 "HXT11 -- transport -- Low-affinity glucose permease, member of hexose transporter family of major facilitator superfamily (MFS)" YOL160W YOL160W 32 0.798628326 iYOL161C-0 iYOL161C-1 0.649630918 0.672117373 0.124742862 YOL160W -- unknown -- unknown function YOL162W YOL162W 0.636474017 0.585928837 YOL162W -- unknown -- unknown function YOL163W YOL163W 31 0.250495245 iYOL164W 0.161822096 0.44612929 0.281823418 YOL163W -- unknown -- weak similarity to Pseudomonas putida phthalate transporter YOL166C YOL166C 0.992200662 iYOL166C 0.973997267 0.695214309 0.614278752 YOL166C -- unknown -- unknown function YOR024W YOR024W 0.404789808 iYOR023C 0.200981889 0.760918161 0.130667325 YOR024W -- unknown -- unknown function YOR029W YOR029W 0.307673628 iYOR028C 0.442425046 0.197715628 YOR029W -- unknown -- unknown function YOR032C HMS1 19 0.720258915 iYOR032C 0.89568449 0.173564454 0.085342418 "HMS1 -- pseudohyphal growth -- Regulator of pseudohyphal differentiation, probable transcription factor of myc family" YOR041C YOR041C 23 0.656815783 0.453187889 YOR041C -- unknown -- unknown function YOR050C YOR050C 0.530217463 iYOR050C 0.443679592 0.841101357 0.401790756 YOR050C -- unknown -- unknown function YOR055W YOR055W 0.67151092 0.693602984 YOR055W -- unknown -- unknown function YOR068C YOR068C 0.282576723 iYOR068C 0.291961717 0.357505848 0.276137271 YOR068C -- unknown -- unknown function YOR082C YOR082C 18 0.109170393 0.140432099 YOR082C -- unknown -- unknown function YOR083W YOR083W 0.51280311 0.861111111 YOR083W -- unknown -- unknown function YOR121C YOR121C 44 0.335474743 iYOR121C 0.378419578 0.325330325 0.327131377 YOR121C -- unknown -- unknown function YOR134W BAG7 34 0.302081696 iYOR133W 0.27931022 0.764338024 0.898653867 BAG7 -- signaling -- Putative GTPase-activating protein (GAP) YOR139C YOR139C 35 0.365635698 0.54824265 YOR139C -- unknown -- unknown function YOR140W SFL1 16 0.212949526 0.190545809 SFL1 -- cell surface assembly -- Transcriptional repressor interacting with SRB mediator subcomplex of RNA polymerase IIhas domains homologous to myc oncoprotein and yeast Hsf1p YOR170W YOR170W 0.758501143 0.597164035 YOR170W -- unknown -- unknown function YOR177C YOR177C 20 0.38371092 iYOR177C 0.257305353 0.604596147 0.055130917 "YOR177C -- unknown -- unknown function, putative coiled-coil protein induced early in sporulation" YOR183W YOR183W 11 0.97987616 iYOR182C 0.820741405 0.069210293 0.42985365 YOR183W -- unknown -- unknown function YOR186W YOR186W 16 0.776833414 iYOR185C 0.416727269 0.87346981 0.492202729 YOR186W -- unknown -- unknown function YOR190W SPR1 14 0.163050447 iYOR189W 0.258491027 0.304856744 0.166249899 "SPR1 -- sporulation -- Sporulation-specific exo-beta-1,3-glucanase, involved in late sporulation" YOR192C YOR192C 16 0.111428455 iYOR192C-0 iYOR192C-1 0.437448356 0.390150651 0.137426901 0.777668065 0.297666599 YOR192C -- unknown -- Probable low affinity thiamine transporter YOR199W YOR199W 0.593691564 iYOR198C 0.314674164 0.38281514 0.021206489 YOR199W -- unknown -- unknown function YOR214C YOR214C 0.271383486 iYOR214C 0.249856285 0.477893057 0.130354118 YOR214C -- unknown -- unknown function YOR235W 0.987736951 iYOR234C 0.988788132 0.250625151 0.38624208 YOR255W YOR255W 0.160373739 iYOR254C 0.125487127 0.271882393 0.039606356 YOR255W -- unknown -- unknown function YOR263C YOR263C 12 0.480781642 0.431364725 YOR263C -- unknown -- weak similarity to adenosine A1 receptors YOR268C YOR268C 13 0.418202581 iYOR268C 0.881708208 0.064633322 0.349036057 YOR268C -- unknown -- unknown function YOR277C YOR277C 0.406175189 iYOR277C 0.796308348 0.607566347 0.796629299 YOR277C -- unknown -- unknown function YOR282W YOR282W 27 0.152450409 0.086744639 YOR282W -- unknown -- unknown function YOR298W YOR298W 28 0.346619851 iYOR297C 0.890437441 0.384931838 0.866045688 YOR298W -- unknown -- Putative acyltransferase YOR300W YOR300W 12 0.669027619 0.535936114 YOR300W -- unknown -- unknown function YOR314W YOR314W 10 0.724993722 iYOR313C 0.648962339 0.629954882 0.189864326 YOR314W -- unknown -- unknown function YOR325W YOR325W 0.294390418 0.561507266 YOR325W -- unknown -- unknown function YOR339C UBC11 28 0.677469698 iYOR339C 0.659511577 0.177167257 0.224285646 "UBC11 -- protein degradation, ubiquitin-mediated (putative) -- similarity to ubiquitin-conjugating enzymes" YOR345C YOR345C 21 0.321531954 0.766596842 YOR345C -- unknown -- unknown function YOR348C PUT4 17 0.735381924 iYOR348C 0.632199375 0.433048663 0.502782931 PUT4 -- transport -- Proline permease required for high-affinity proline transport YOR351C MEK1 0.37234958 iYOR351C 0.193993972 0.551643571 0.352673583 MEK1 -- meiosis -- Serine/threonine protein kinase required for meiotic recombination YOR358W HAP5 37 0.529677942 iYOR357C 0.453573438 0.047904698 0.28158234 "HAP5 -- respiration -- Component (with Hap2p, Hap3p, and Hap4p) of heterotrimeric CCAAT-binding factor" YOR364W YOR364W 21 0.630932501 iYOR363C 0.407628226 0.330288818 0.301835595 YOR364W -- unknown -- unknown function YOR365C YOR365C 15 0.854253039 0.523543496 YOR365C -- unknown -- unknown function YOR376W YOR376W 0.780623431 iYOR375C 0.446154014 0.715872624 0.503333965 YOR376W -- unknown -- weak similarity to Na+/K+-exchanging ATPases YOR378W YOR378W 33 0.350742351 iYOR377W-0 iYOR377W-1 0.301344791 0.355646811 0.483255163 0.159217877 0.452568134 YOR378W -- unknown -- Member of multidrug-resistance 14-spanner family of major facilitator superfamily (MFS-MDR) YOR384W FRE5 14 0.39019043 iYOR383C 0.299554502 0.229449322 0.082442139 "FRE5 -- unknown -- similarity to Fre2p, subject to regulation by iron" YOR391C YOR391C 21 0.555108018 0.158368274 YOR391C -- unknown -- unknown function YOR392W YOR392W 27 0.780770158 0.20726257 YOR392W -- unknown -- unknown function YOR393W ERR1 23 0.848075781 iYOR392W 0.464410715 0.167235218 0.05232355 "ERR1 -- unknown -- Enolase-related subtelomeric sequence, identical to Err2p" YPL021W SRD2 17 0.435536702 iYPL022W 0.432037671 0.513626834 0.712745824 SRD2 -- cell wall biogenesis (putative) -- similarity to Srd1p YPL025C YPL025C 0.404013569 iYPL025C 0.122477117 0.36632083 0.241720176 YPL025C -- unknown -- unknown function YPL027W YPL027W 0.149097087 iYPL028W 0.537208999 0.17683339 0.507117584 YPL027W -- unknown -- unknown function YPL033C YPL033C 0.046386365 iYPL033C 0.16777876 0.473889997 0.159523042 YPL033C -- unknown -- unknown function YPL044C YPL044C 0.090827107 0.01379366 YPL044C -- unknown -- unknown function YPL054W LEE1 0.047160844 iYPL055C 0.265548855 0.087150838 0.129433062 LEE1 -- unknown -- unknown function YPL062W YPL062W 0.067913226 iYPL063W 0.168852504 0.01799441 0.14953271 YPL062W -- unknown -- unknown function YPL073C YPL073C 0.403483462 0.499274895 YPL073C -- unknown -- unknown function YPL102C YPL102C 15 0.328681034 0.44663869 YPL102C -- unknown -- unknown function YPL121C MEI5 11 0.519554797 iYPL121C 0.296925912 0.173283683 0.472123751 "MEI5 -- meiosis, synapsis and recombination -- Meiotic synapsis and meiotic recombination" YPL130W SPO19 0.443062426 iYPL131W 0.80542935 0.668722541 0.70464067 "SPO19 -- sporulaiton -- Sporulation specific protein, putative glycophosphatidylinositol (GPI)-anchored spore wall protein" YPL136W YPL136W 0.294047156 0.816649196 YPL136W -- unknown -- unknown function YPL147W PXA1 26 0.411662376 iYPL148C 0.382908594 0.765025991 0.712529928 "PXA1 -- transport -- long-chain fatty acid transport across the peroxisomal membrane, member of ATP-binding cassette (ABC) superfamily, has similarity to a human gene associated with adrenoleukodystrophy" YPL165C YPL165C 0.792586473 iYPL165C 0.459064858 0.936951317 0.244978624 YPL165C -- unknown -- unknown function YPL185W YPL185W 0.42386888 0.205936865 YPL185W -- unknown -- unknown function YPL186C YPL186C 20 0.337046309 0.174951267 YPL186C -- unknown -- unknown function YPL187W MFALPHA1 20 0.856256125 iYPL188W 0.701505724 0.272645684 0.50154321 "MFALPHA1 -- mating -- Mating pheromone alpha-factor, identical or nearly identical to the two forms of alpha-factor encoded by MFALPHA2" YPL200W YPL200W 0.667729496 iYPL201C 0.536093713 0.319368353 0.0970029 YPL200W -- unknown -- unknown function YPL201C YPL201C 30 0.418763613 iYPL201C 0.536093713 0.360936408 0.0970029 "YPL201C -- unknown -- unknown function, induced during aerobic growth" YPL205C YPL205C 18 0.319357062 0.225146199 YPL205C -- unknown -- unknown function YPL223C GRE1 23 0.269411668 iYPL223C 0.349179495 0.125625087 0.473846654 GRE1 -- unknown -- induced by osmotic stress YPL248C GAL4 0.480243052 iYPL248C 0.224648859 0.19792498 0.162997904 GAL4 -- galactose regulation -- Transcription factor involved in expression of galactose-induced genesphosphorylation correlates with activity YPL257W YPL257W 18 0.420819565 iYPL258C YPLCdelta1 0.200088897 0.567580056 0.760814046 0.365652981 0.45580014 YPL257W -- unknown -- unknown function YPL269W KAR9 0.161796654 iYPL270W 0.112442664 0.538068635 0.076538833 "KAR9 -- cytoskeleton -- cell cortex required for the congression (nuclear migration) step of karyogamy, involved in proper orientation of cytoplasmic microtubules" YPL276W YPL276W 0.331871866 iYPL277C 0.469513258 0.258948408 0.488032844 YPL276W -- unknown -- similarity to formate dehydrogenases YPL280W YPL280W 17 0.582912217 iYPL281C 0.779128079 0.250555418 0.090021779 YPL280W -- unknown -- unknown function YPL281C ERR2 0.798901836 iYPL281C 0.779128079 0.166572558 0.090021779 "ERR2 -- unknown -- Enolase-related subtelomeric sequence, identical to Err1p" YPR007C SPO69 13 0.190032732 iYPR007C YPRCdelta13 0.517242556 0.542050384 0.352201258 0.255147646 0.43485975 SPO69 -- sporulation -- meiosis and sporulation YPR014C YPR014C 0.171959161 iYPR014C-0 iYPR014C-1 0.577779564 0.550948898 0.505848189 0.907058001 0.57524891 YPR014C -- unknown -- unknown function YPR015C YPR015C 0.041081346 iYPR015C 0.253887934 0.069694726 0.225778132 YPR015C -- unknown -- similarity to human GT box-binding protein (SP YPR027C YPR027C 34 0.650064145 iYPR027C tF(GAA)P2 0.514966005 0.682154939 0.724146671 0.502872592 0.402553871 YPR027C -- unknown -- similarity to Ynl019p and Ynl033p YPR038W 0.178068977 0.035006498 YPR039W 0.172441515 0.01600065 YPR054W SMK1 27 0.500527289 0.788994521 SMK1 -- sporulation -- Sporulation-specific protein kinase of MAP family required for completion of sporulation YPR059C 17 0.611614129 iYPR059C 0.424372818 0.696648045 0.40613922 YPR064W YPR064W 0.232254222 iYPR063C 0.395372382 0.153346329 0.83345676 YPR064W -- unknown -- unknown function YPR076W YPR076W 0.631006721 0.757634828 YPR076W -- unknown -- unknown function YPR078C YPR078C 60 0.618846841 iYPR078C 0.663966903 0.400069881 0.173300032 YPR078C -- unknown -- unknown function YPR089W YPR089W 0.36360133 iYPR088C 0.070565175 0.352987421 0.053197065 YPR089W -- unknown -- unknown function YPR092W YPR092W 27 0.77747117 0.520329186 YPR092W -- unknown -- unknown function YPR096C YPR096C 19 0.757846356 iYPR096C 0.314670834 0.670045401 0.127369525 YPR096C -- unknown -- unknown function YPR112C MRD1 13 0.485706942 iYPR112C 0.202915079 0.269854681 0.151904263 "MRD1 -- unknown -- similarity to Pab1p, Pub1p, Nsr1p, Nop4p and other RNA-binding proteins, contains four RNA recognition (RRM) domains" YPR116W YPR116W 0.714855326 iYPR115W 0.144356305 0.841893781 0.120020964 YPR116W -- unknown -- unknown function YPR123C YPR123C 18 0.1547864 0.246588694 YPR123C -- unknown -- unknown function YPR136C YPR136C 0.316733974 0.339641771 YPR136C -- unknown -- unknown function YPR142C YPR142C 26 0.069495798 0.171133853 YPR142C -- unknown -- unknown function YPR150W YPR150W 0.441760331 iYPR149W 0.599010122 0.312656288 0.36223123 YPR150W -- unknown -- unknown function YPR151C YPR151C 34 0.115192328 iYPR151C 0.585305453 0.276264905 0.344785575 "YPR151C -- unknown -- unknown function, induced during aerobic growth" YPR157W YPR157W 0.10371517 iYPR156C 0.294502549 0.316764133 0.613277473 YPR157W -- unknown -- unknown function YPR168W NUT2 0.449249907 iYPR167C 0.500002663 0.522985705 0.519953921 NUT2 -- mating type switching -- Subunit of RNA polymerase II holoenzyme mediator (SRB) subcomplex YPR170C 0.558273161 iYPR170C 0.218322547 0.80035485 0.300676764 YPR177C YPR177C 0.17672699 0.195987654 YPR177C -- unknown -- unknown functionquestionable ORF YPR192W AQY1 0.312370446 iYPR191W 0.738291204 0.432732659 0.44711051 "AQY1 -- transport, water -- Aquaporin water channel protein, member of MIP (major intrinsic protein) family of aquaglyceroporin transmembrane channels" YPR193C HPA2 0.168583065 iYPR193C 0.432861293 0.284756584 0.350495181 "HPA2 -- chromatin structure -- Histone and other protein acetyltransferase, member of GCN5 N-acetyltransferase (GNAT) superfamily" YPR195C YPR195C 11 0.345294853 iYPR195C-0 iYPR195C-1 0.203664471 0.586841833 0.219545601 0.585296807 0.523574426 YPR195C -- unknown -- unknown function YPR196W YPR196W 18 0.246593028 iYPR195C-0 iYPR195C-1 0.203664471 0.586841833 0.673423783 0.585296807 0.523574426 "YPR196W -- unknown -- Positive regulator of maltose pathway MAL genes, contains a Zn[2]-Cys[6] fungal-type binuclear cluster domain in the N-terminal region" YPR197C 0.08900639 0.080047885 YPR200C ARR2 0.25147182 iYPR200C 0.499354162 0.377069956 0.350862877 ARR2 -- arsenic resistance -- Arsenic-resistance protein YPR201W ARR3 0.368030369 iYPR200C 0.499354162 0.465762171 0.350862877 ARR3 -- arsenic resistance -- Arsenic-resistance protein