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Chromosome sizes

Calculation of novel band sizes from PFG in Figure 1.

Figure 2 datafiles

Each file includes filtered log(base2)ratios of evolved strain (labeled red unless otherwise noted) to ancestor strain (green unless otherwise noted) for two experiments, the average of those two experiments, a running average over nine genes, conversion to a copy number, and separation into "high" and "low" categories, colored red and green, respectively, in Figure 2 of the paper. CP1ABaCGH.xls also contains the values used as cutoffs to separate the data into "high" and "low." I've also included the raw, unprocessed data files for each experiment. The raw data files are named with the Experiment ID from the Stanford Microarray Database, in which the data are deposited.

Comparison Filtered data with analysis Raw data
CP1AB vs CP1AB CP1ABaCGH.xls 13020.xls
13021.xls
E1 vs CP1AB E1aCGH.xls 11568.xls
12140.xls
E2 vs CP1AB E2aCGH.xls11569.xls
12141.xls
E3 vs CP1AB E3aCGH.xls 11570.xls
13019.xls
E4 vs CP1AB E4aCGH.xls 29591.xls
29598.xls (dyes reversed)
E5 vs CP1AB E5aCGH.xls 29593.xls
29599.xls (dyes reversed)
E6 vs CP1AB E6aCGH.xls 29594.xls
29613.xls (dyes reversed)
E7 vs CP1AB E7aCGH.xls 29595.xls
29614.xls (dyes reversed)
E8 vs CP1AB E8aCGH.xls 29596.xls
29615.xls (dyes reversed)

Figure 4 datafiles

Each file contains the log(base2)ratio of DNA eluted from the excised PFGE band from the evolved strain to DNA eluted from a CP1AB plug containing whole genome DNA and a running average of these data over three genes. For each comparison, there are files with the filtered data, the division into enriched and unenriched for the relevant chromosomes, and the raw data.

Comparison Filtered data analysis Raw data
E1 lower band vs CP1AB E1lowerband.xls Chromosome 1428119.xls
E4 band vs CP1AB E4band.xlsChromosome 7, Chromosome 15 28120.xls
E5 band vs CP1AB E5band.xlsChromosome 4, Chromosome 14 32126.xls
E6 band vs CP1AB E6band.xlsChromosome 14 28170.xls
E7 band vs CP1AB E7band.xlsChromosome 15 28171.xls
E8 band vs CP1AB E8band.xlsChromosome 4, Chromosome 15 28172.xls

Spore array CGH

These files have the array CGH data for the E1 and E4 spores (red) vs the ancestor strain (green). These are raw data files. The names reflect the Experiment ID number in SMD.

Strain comparisonRaw data
E1 spores
E1.1B vs CP1AB11925.xls
E1.1C vs CP1AB12559.xls
E1.2C vs CP1AB11927.xls
E1.2D vs CP1AB12562.xls
E1.4C vs CP1AB11929.xls
E1.4D vs CP1AB12563.xls
E1.5A vs CP1AB11931.xls
E1.5B vs CP1AB12564.xls
E1.6A vs CP1AB11932.xls
E1.6B vs CP1AB12576.xls
E1.7A vs CP1AB12565.xls
E1.7D vs CP1AB12577.xls
E4 spores
E4.1A vs CP1AB28173.xls
E4.1B vs CP1AB28174.xls
E4.2A vs CP1AB28175.xls
E4.2B vs CP1AB28181.xls
E4.3A vs CP1AB28187.xls
E4.3B vs CP1AB28189.xls
E4.4A vs CP1AB28190.xls
E4.4B vs CP1AB28191.xls

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