Figure 5 The transcriptional response to serum suggests a multifaceted role for fibroblasts in the physiology of wound healing. The features of the transcriptional program of fibroblasts in response to serum stimulation that appear to be related to various aspects of the wound healing process and fibroblast proliferation, are shown using the same convention for representing changes in transcript levels as was used in Figure 2 and 4. The numbers in panels C and G refer to genes whose products serve as signals to: neutrophils (C1), monocytes and macrophages (C2) T-lymphocytes (C3), B-lymphocytes (C4) and melanocytes (G1).