pT181


Vector IG Sequence Link :
General : plasmid ds-DNA 4437 BP
Functions : (cloning)
Selection : ()
Copy Number :
Hosts : (Staphylococcus aureus)(Staphylococcus)
Suppliers : ()
Misc.Comments : pT181 occurs naturally in staphylococcus aureus and encodes inducible resistance to tetracycline. it contains four open reading frames encoding four putative polypeptides a, 37.5 kda; b, 35 kda; c, 23 kda, and d, 18 kda [3]. polypeptide a is the repc protein [2] (bases 3563-557). polypeptides b and d (bases 2595-3482 and 2180-2638, respectively) are involved in tetracycline resistance [3]. there is no known function for polypeptide c and deletion of a large portion of it causes no noticeable changes [3]. Replication, originating in a 168 bp span, proceeds unidirectionally and clockwise (anticlockwise as the map is conventionally drawn) [2].
Parents : (Staphylococcus)
Siblings : (pC221)(pE194)
Descendents : (pSA series from pRN5101 from pE194)

NCBI ENTREZ Link :


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