Index

Future Directions

  1. Incorporate more sensitive sequence search results.

  2. More flexible browsing of results.

  3. More sophisticated clustering scheme.

    • Better handling of multi-domain proteins and weak similarities.

  4. Graceful handling of changes in the genomic datasets in the analysis results.

    • New protein coding regions
    • Removal of incorrect ORF predictions
    • Correction of errors in the genomic sequence
    • Sequence name changes

  5. Extended annotation support.

    • Incorporating controlled vocabularies and ontologies for gene function, cellular location, phenotype, etc.
    • Increased granularity of annotations (sequence level).
    • Browsing tools
    • Confirm/refute transitivity

  6. Comparative genomics framework to incorporate additional completed genomes.

Comparing the S. cerevisiae and C. elegans Proteomes
Stephen A. Chervitz
22 Feb 1999
sac@neomorphic.com